Incidental Mutation 'R7205:Myh9'
| ID |
560568 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh9
|
| Ensembl Gene |
ENSMUSG00000022443 |
| Gene Name |
myosin, heavy polypeptide 9, non-muscle |
| Synonyms |
Myhn-1, myosin IIA, Fltn, Myhn1, D0Jmb2, E030044M24Rik, NMHC II-A |
| MMRRC Submission |
045283-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7205 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
77644787-77726375 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 77667672 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Arginine
at position 587
(K587R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000016771
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000016771]
[ENSMUST00000231192]
|
| AlphaFold |
Q8VDD5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000016771
AA Change: K587R
PolyPhen 2
Score 0.081 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000016771
Gene: ENSMUSG00000022443
AA Change: K587R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
29 |
69 |
3.4e-11 |
PFAM |
|
MYSc
|
75 |
777 |
N/A |
SMART |
|
IQ
|
778 |
800 |
1.46e-3 |
SMART |
|
Pfam:Myosin_tail_1
|
841 |
1921 |
N/A |
PFAM |
|
low complexity region
|
1948 |
1959 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000231192
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
97% (99/102) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
PHENOTYPE: Homozygous null mice display embryonic lethality. Heterozygous null mice display hearing loss with incomplete penetrance. Mice homozygous or heterozygous for one of several knock-in alleles exhibit macrothrombocytopenia, nephritis, cataracts and deafness. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 101 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca15 |
A |
T |
7: 119,993,587 (GRCm39) |
K1269M |
possibly damaging |
Het |
| Adgrl2 |
A |
T |
3: 148,564,585 (GRCm39) |
Y332N |
probably damaging |
Het |
| Adgrv1 |
C |
T |
13: 81,627,777 (GRCm39) |
V3695I |
probably benign |
Het |
| Aldh1l1 |
A |
T |
6: 90,575,257 (GRCm39) |
Y848F |
probably damaging |
Het |
| Ambra1 |
T |
C |
2: 91,598,103 (GRCm39) |
V88A |
possibly damaging |
Het |
| Ankrd12 |
C |
T |
17: 66,292,160 (GRCm39) |
R1091Q |
probably damaging |
Het |
| Apob |
T |
G |
12: 8,055,087 (GRCm39) |
V1362G |
probably damaging |
Het |
| Arhgap17 |
A |
G |
7: 122,905,661 (GRCm39) |
L328P |
probably damaging |
Het |
| Arhgap27 |
A |
C |
11: 103,235,367 (GRCm39) |
V9G |
probably benign |
Het |
| Arhgap33 |
A |
T |
7: 30,232,434 (GRCm39) |
D34E |
probably damaging |
Het |
| Ash1l |
A |
G |
3: 88,873,259 (GRCm39) |
D14G |
probably benign |
Het |
| Atf6b |
T |
C |
17: 34,872,703 (GRCm39) |
Y575H |
probably damaging |
Het |
| Bcl2l2 |
T |
G |
14: 55,122,058 (GRCm39) |
S74A |
probably benign |
Het |
| Begain |
T |
C |
12: 109,004,794 (GRCm39) |
T73A |
possibly damaging |
Het |
| Bicdl1 |
C |
T |
5: 115,808,340 (GRCm39) |
R264Q |
probably damaging |
Het |
| Ccdc180 |
A |
G |
4: 45,914,588 (GRCm39) |
D701G |
probably benign |
Het |
| Cd200r4 |
G |
T |
16: 44,653,529 (GRCm39) |
V146L |
probably damaging |
Het |
| Cd226 |
G |
A |
18: 89,265,322 (GRCm39) |
C200Y |
probably damaging |
Het |
| Cdcp3 |
T |
C |
7: 130,879,352 (GRCm39) |
|
probably null |
Het |
| Cdhr18 |
T |
C |
14: 13,866,032 (GRCm38) |
T286A |
|
Het |
| Cdk12 |
A |
G |
11: 98,115,451 (GRCm39) |
N864S |
unknown |
Het |
| Cfhr4 |
A |
T |
1: 139,680,788 (GRCm39) |
Y243* |
probably null |
Het |
| Clcnkb |
A |
T |
4: 141,135,946 (GRCm39) |
L413Q |
probably damaging |
Het |
| Cldn10 |
T |
C |
14: 119,099,255 (GRCm39) |
V123A |
possibly damaging |
Het |
| Cnn1 |
T |
A |
9: 22,017,078 (GRCm39) |
|
probably null |
Het |
| Cpa5 |
C |
A |
6: 30,630,829 (GRCm39) |
Q364K |
probably benign |
Het |
| Cstdc5 |
T |
C |
16: 36,187,809 (GRCm39) |
I19V |
probably benign |
Het |
| Ddx11 |
A |
G |
17: 66,437,766 (GRCm39) |
E164G |
probably benign |
Het |
| Dnah12 |
G |
A |
14: 26,500,869 (GRCm39) |
|
probably null |
Het |
| Drc7 |
T |
A |
8: 95,804,549 (GRCm39) |
Y855N |
probably damaging |
Het |
| Fam20b |
C |
A |
1: 156,529,968 (GRCm39) |
|
probably null |
Het |
| Fip1l1 |
T |
A |
5: 74,748,736 (GRCm39) |
|
probably null |
Het |
| Flt4 |
A |
G |
11: 49,525,125 (GRCm39) |
D657G |
probably null |
Het |
| Fmo3 |
T |
A |
1: 162,781,857 (GRCm39) |
T499S |
possibly damaging |
Het |
| Fyco1 |
C |
T |
9: 123,651,491 (GRCm39) |
G1190S |
probably benign |
Het |
| Galnt17 |
C |
A |
5: 131,335,590 (GRCm39) |
|
probably benign |
Het |
| Ggcx |
T |
C |
6: 72,404,987 (GRCm39) |
I465T |
probably damaging |
Het |
| Gm7361 |
T |
A |
5: 26,466,116 (GRCm39) |
N159K |
probably damaging |
Het |
| Golgb1 |
A |
G |
16: 36,695,663 (GRCm39) |
N54S |
unknown |
Het |
| Grin2c |
G |
A |
11: 115,141,876 (GRCm39) |
P848S |
probably damaging |
Het |
| Grina |
T |
C |
15: 76,133,287 (GRCm39) |
V285A |
probably damaging |
Het |
| Gtpbp6 |
A |
G |
5: 110,252,478 (GRCm39) |
L381P |
probably damaging |
Het |
| Herc2 |
G |
T |
7: 55,832,388 (GRCm39) |
G3028V |
probably damaging |
Het |
| Ibsp |
A |
T |
5: 104,458,297 (GRCm39) |
Y278F |
probably damaging |
Het |
| Ints4 |
T |
A |
7: 97,184,433 (GRCm39) |
L846* |
probably null |
Het |
| Kif17 |
A |
G |
4: 138,021,077 (GRCm39) |
K849E |
probably benign |
Het |
| Krt77 |
G |
A |
15: 101,777,806 (GRCm39) |
P83L |
probably benign |
Het |
| Ky |
T |
G |
9: 102,419,491 (GRCm39) |
D499E |
probably damaging |
Het |
| Lrp3 |
A |
T |
7: 34,902,051 (GRCm39) |
M610K |
probably damaging |
Het |
| Lrrfip1 |
T |
A |
1: 91,019,338 (GRCm39) |
D156E |
probably benign |
Het |
| Map6 |
C |
A |
7: 98,918,257 (GRCm39) |
H343Q |
probably benign |
Het |
| Micu2 |
G |
T |
14: 58,191,606 (GRCm39) |
D148E |
probably benign |
Het |
| Mks1 |
T |
A |
11: 87,747,428 (GRCm39) |
S153T |
probably benign |
Het |
| Msantd5f3 |
A |
G |
4: 73,573,157 (GRCm39) |
Y132C |
probably damaging |
Het |
| Muc6 |
AGGCGCAGAAACCCTGGC |
AGGC |
7: 141,214,363 (GRCm39) |
|
probably null |
Het |
| Neb |
T |
C |
2: 52,086,368 (GRCm39) |
Y5478C |
probably damaging |
Het |
| Nelfe |
G |
A |
17: 35,069,912 (GRCm39) |
|
probably null |
Het |
| Nps |
T |
A |
7: 134,870,510 (GRCm39) |
L11I |
probably damaging |
Het |
| Nsd1 |
A |
T |
13: 55,394,283 (GRCm39) |
D731V |
probably damaging |
Het |
| Nup50 |
A |
G |
15: 84,817,859 (GRCm39) |
T93A |
probably benign |
Het |
| Nup98 |
A |
T |
7: 101,844,248 (GRCm39) |
F29Y |
unknown |
Het |
| Oprd1 |
A |
G |
4: 131,841,112 (GRCm39) |
I282T |
probably damaging |
Het |
| Or4c103 |
T |
C |
2: 88,513,767 (GRCm39) |
H103R |
possibly damaging |
Het |
| Or5p50 |
T |
C |
7: 107,421,782 (GRCm39) |
N298S |
probably benign |
Het |
| Or6b3 |
A |
T |
1: 92,439,573 (GRCm39) |
M59K |
probably benign |
Het |
| Or6d12 |
A |
G |
6: 116,492,936 (GRCm39) |
Y66C |
probably damaging |
Het |
| Osbp2 |
T |
C |
11: 3,662,134 (GRCm39) |
I240V |
probably damaging |
Het |
| Otub2 |
C |
A |
12: 103,359,163 (GRCm39) |
P84Q |
probably benign |
Het |
| Parp9 |
A |
T |
16: 35,777,360 (GRCm39) |
I435F |
probably benign |
Het |
| Pcdh18 |
C |
T |
3: 49,709,923 (GRCm39) |
R464H |
probably benign |
Het |
| Pcsk6 |
G |
T |
7: 65,675,156 (GRCm39) |
|
probably null |
Het |
| Ptgs2 |
G |
A |
1: 149,978,512 (GRCm39) |
R208Q |
probably benign |
Het |
| Rab11b |
G |
A |
17: 33,968,841 (GRCm39) |
R51C |
probably damaging |
Het |
| Rad1 |
A |
G |
15: 10,493,343 (GRCm39) |
I257V |
probably benign |
Het |
| Rbms3 |
C |
T |
9: 116,415,085 (GRCm39) |
|
probably null |
Het |
| Rxfp2 |
A |
T |
5: 149,983,364 (GRCm39) |
I300L |
probably benign |
Het |
| Rxfp2 |
C |
A |
5: 149,983,368 (GRCm39) |
T301K |
probably benign |
Het |
| Sars2 |
G |
T |
7: 28,443,733 (GRCm39) |
A112S |
probably benign |
Het |
| Scn10a |
T |
C |
9: 119,442,616 (GRCm39) |
D1543G |
probably damaging |
Het |
| Serpinb1b |
A |
G |
13: 33,271,406 (GRCm39) |
H59R |
probably benign |
Het |
| Sgsm2 |
T |
A |
11: 74,745,319 (GRCm39) |
D661V |
possibly damaging |
Het |
| Smad6 |
C |
A |
9: 63,927,688 (GRCm39) |
V207L |
probably damaging |
Het |
| Son |
TCCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCAGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
TCCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
16: 91,457,183 (GRCm39) |
|
probably benign |
Het |
| Spata31h1 |
A |
T |
10: 82,125,161 (GRCm39) |
D2616E |
probably benign |
Het |
| Tenm2 |
C |
T |
11: 35,939,956 (GRCm39) |
R1390Q |
probably damaging |
Het |
| Tmem132a |
T |
A |
19: 10,844,295 (GRCm39) |
Q101L |
probably damaging |
Het |
| Tmem151a |
A |
G |
19: 5,132,801 (GRCm39) |
V135A |
probably damaging |
Het |
| Trappc10 |
T |
C |
10: 78,046,262 (GRCm39) |
K443E |
probably damaging |
Het |
| Trrap |
A |
T |
5: 144,779,517 (GRCm39) |
N3161I |
possibly damaging |
Het |
| Tspan32 |
G |
T |
7: 142,558,863 (GRCm39) |
R6L |
possibly damaging |
Het |
| Tut7 |
C |
G |
13: 59,936,364 (GRCm39) |
D1246H |
probably damaging |
Het |
| Ugt2a2 |
T |
C |
5: 87,608,468 (GRCm39) |
D457G |
possibly damaging |
Het |
| Ulk2 |
A |
T |
11: 61,725,657 (GRCm39) |
S140T |
possibly damaging |
Het |
| Upf1 |
C |
T |
8: 70,792,695 (GRCm39) |
A338T |
possibly damaging |
Het |
| Usp43 |
C |
T |
11: 67,774,110 (GRCm39) |
R460Q |
probably null |
Het |
| Uxs1 |
A |
G |
1: 43,856,118 (GRCm39) |
|
probably benign |
Het |
| Vmn1r59 |
A |
G |
7: 5,457,725 (GRCm39) |
C12R |
probably damaging |
Het |
| Wdr64 |
A |
G |
1: 175,617,499 (GRCm39) |
D693G |
probably benign |
Het |
| Wnk1 |
A |
T |
6: 119,920,839 (GRCm39) |
|
probably null |
Het |
| Wnt2 |
G |
T |
6: 18,028,046 (GRCm39) |
R63S |
probably benign |
Het |
| Zfp418 |
A |
T |
7: 7,184,562 (GRCm39) |
Q175L |
probably benign |
Het |
|
| Other mutations in Myh9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00796:Myh9
|
APN |
15 |
77,681,195 (GRCm39) |
splice site |
probably benign |
|
|
IGL01105:Myh9
|
APN |
15 |
77,665,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01137:Myh9
|
APN |
15 |
77,653,742 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01399:Myh9
|
APN |
15 |
77,651,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01666:Myh9
|
APN |
15 |
77,646,131 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL01832:Myh9
|
APN |
15 |
77,675,953 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01933:Myh9
|
APN |
15 |
77,665,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02049:Myh9
|
APN |
15 |
77,654,070 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02237:Myh9
|
APN |
15 |
77,670,854 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02243:Myh9
|
APN |
15 |
77,651,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02248:Myh9
|
APN |
15 |
77,670,814 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02292:Myh9
|
APN |
15 |
77,692,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02315:Myh9
|
APN |
15 |
77,654,173 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02427:Myh9
|
APN |
15 |
77,660,004 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02675:Myh9
|
APN |
15 |
77,673,130 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02727:Myh9
|
APN |
15 |
77,675,942 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02749:Myh9
|
APN |
15 |
77,692,186 (GRCm39) |
nonsense |
probably null |
|
|
IGL02887:Myh9
|
APN |
15 |
77,680,220 (GRCm39) |
nonsense |
probably null |
|
|
IGL02926:Myh9
|
APN |
15 |
77,671,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02945:Myh9
|
APN |
15 |
77,646,205 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03137:Myh9
|
APN |
15 |
77,675,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0784:Myh9
|
UTSW |
15 |
77,661,209 (GRCm39) |
splice site |
probably benign |
|
|
R1375:Myh9
|
UTSW |
15 |
77,653,568 (GRCm39) |
splice site |
probably null |
|
|
R1535:Myh9
|
UTSW |
15 |
77,662,013 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1563:Myh9
|
UTSW |
15 |
77,656,057 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1629:Myh9
|
UTSW |
15 |
77,648,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Myh9
|
UTSW |
15 |
77,660,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1635:Myh9
|
UTSW |
15 |
77,655,367 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1693:Myh9
|
UTSW |
15 |
77,697,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Myh9
|
UTSW |
15 |
77,657,464 (GRCm39) |
unclassified |
probably benign |
|
|
R2010:Myh9
|
UTSW |
15 |
77,656,147 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2048:Myh9
|
UTSW |
15 |
77,655,332 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R2078:Myh9
|
UTSW |
15 |
77,648,112 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2092:Myh9
|
UTSW |
15 |
77,648,550 (GRCm39) |
nonsense |
probably null |
|
|
R2376:Myh9
|
UTSW |
15 |
77,667,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2922:Myh9
|
UTSW |
15 |
77,697,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3709:Myh9
|
UTSW |
15 |
77,657,547 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3710:Myh9
|
UTSW |
15 |
77,657,547 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3737:Myh9
|
UTSW |
15 |
77,651,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3738:Myh9
|
UTSW |
15 |
77,651,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3739:Myh9
|
UTSW |
15 |
77,651,012 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4299:Myh9
|
UTSW |
15 |
77,654,164 (GRCm39) |
missense |
probably benign |
|
|
R4384:Myh9
|
UTSW |
15 |
77,675,912 (GRCm39) |
splice site |
probably benign |
|
|
R4514:Myh9
|
UTSW |
15 |
77,648,200 (GRCm39) |
missense |
probably benign |
|
|
R4631:Myh9
|
UTSW |
15 |
77,681,228 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4642:Myh9
|
UTSW |
15 |
77,646,151 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4695:Myh9
|
UTSW |
15 |
77,653,053 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4709:Myh9
|
UTSW |
15 |
77,671,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4766:Myh9
|
UTSW |
15 |
77,692,077 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4826:Myh9
|
UTSW |
15 |
77,673,146 (GRCm39) |
nonsense |
probably null |
|
|
R4842:Myh9
|
UTSW |
15 |
77,653,453 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4946:Myh9
|
UTSW |
15 |
77,657,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5030:Myh9
|
UTSW |
15 |
77,691,998 (GRCm39) |
intron |
probably benign |
|
|
R5055:Myh9
|
UTSW |
15 |
77,648,723 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5202:Myh9
|
UTSW |
15 |
77,665,310 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5413:Myh9
|
UTSW |
15 |
77,692,186 (GRCm39) |
nonsense |
probably null |
|
|
R5435:Myh9
|
UTSW |
15 |
77,653,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5701:Myh9
|
UTSW |
15 |
77,675,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5757:Myh9
|
UTSW |
15 |
77,655,362 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5793:Myh9
|
UTSW |
15 |
77,653,077 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5952:Myh9
|
UTSW |
15 |
77,657,532 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6248:Myh9
|
UTSW |
15 |
77,669,422 (GRCm39) |
nonsense |
probably null |
|
|
R6648:Myh9
|
UTSW |
15 |
77,650,972 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7055:Myh9
|
UTSW |
15 |
77,659,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7106:Myh9
|
UTSW |
15 |
77,659,321 (GRCm39) |
missense |
probably benign |
|
|
R7180:Myh9
|
UTSW |
15 |
77,692,110 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7254:Myh9
|
UTSW |
15 |
77,650,024 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7284:Myh9
|
UTSW |
15 |
77,671,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7417:Myh9
|
UTSW |
15 |
77,648,065 (GRCm39) |
nonsense |
probably null |
|
|
R7695:Myh9
|
UTSW |
15 |
77,650,936 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7750:Myh9
|
UTSW |
15 |
77,667,610 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7854:Myh9
|
UTSW |
15 |
77,675,953 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8220:Myh9
|
UTSW |
15 |
77,648,747 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8324:Myh9
|
UTSW |
15 |
77,673,117 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8837:Myh9
|
UTSW |
15 |
77,661,137 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8944:Myh9
|
UTSW |
15 |
77,655,432 (GRCm39) |
missense |
probably benign |
|
|
R9025:Myh9
|
UTSW |
15 |
77,653,192 (GRCm39) |
missense |
probably benign |
|
|
R9229:Myh9
|
UTSW |
15 |
77,675,017 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9396:Myh9
|
UTSW |
15 |
77,647,496 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Myh9
|
UTSW |
15 |
77,659,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCAGTGTCATGGTCCTTTG -3'
(R):5'- GTTCTTAATGGCCGGCTTCC -3'
Sequencing Primer
(F):5'- ACCAGTGTCATGGTCCTTTGTATGG -3'
(R):5'- ATTTGCAGCCCCTCTGAGAGTG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation