Incidental Mutation 'R7219:Umodl1'
| ID |
561697 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
045291-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7219 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
critical splice acceptor site |
| DNA Base Change (assembly) |
A to G
at 31201236 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066554]
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000066981]
[ENSMUST00000066981]
[ENSMUST00000114555]
[ENSMUST00000114555]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000066554
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000066554
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000066554
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000066981
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000066981
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000066981
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000114555
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000114555
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000114555
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.9480 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
97% (77/79) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
T |
C |
16: 4,667,508 (GRCm39) |
S300P |
unknown |
Het |
| Abhd17a |
T |
A |
10: 80,420,008 (GRCm39) |
K226* |
probably null |
Het |
| Alkbh7 |
T |
A |
17: 57,305,508 (GRCm39) |
H108Q |
probably damaging |
Het |
| Ankrd44 |
A |
C |
1: 54,806,069 (GRCm39) |
H112Q |
probably damaging |
Het |
| Capn3 |
A |
G |
2: 120,333,935 (GRCm39) |
E790G |
probably damaging |
Het |
| Cd47 |
C |
A |
16: 49,728,440 (GRCm39) |
N330K |
possibly damaging |
Het |
| Cd55 |
A |
G |
1: 130,390,343 (GRCm39) |
S22P |
possibly damaging |
Het |
| Cdc25a |
A |
G |
9: 109,718,154 (GRCm39) |
I373V |
probably damaging |
Het |
| Cfap43 |
T |
C |
19: 47,779,912 (GRCm39) |
I514V |
probably benign |
Het |
| Cfap73 |
A |
T |
5: 120,768,200 (GRCm39) |
M186K |
probably benign |
Het |
| Chd9 |
A |
G |
8: 91,728,394 (GRCm39) |
D1270G |
unknown |
Het |
| Ciita |
A |
G |
16: 10,330,121 (GRCm39) |
T802A |
probably benign |
Het |
| Dlgap2 |
A |
G |
8: 14,793,296 (GRCm39) |
E430G |
probably benign |
Het |
| Dlx1 |
C |
A |
2: 71,360,513 (GRCm39) |
S59* |
probably null |
Het |
| Dnaaf3 |
T |
C |
7: 4,531,076 (GRCm39) |
N119S |
probably damaging |
Het |
| Dnah11 |
T |
G |
12: 118,004,830 (GRCm39) |
I2164L |
possibly damaging |
Het |
| Dnah11 |
T |
C |
12: 118,090,624 (GRCm39) |
K1079R |
probably benign |
Het |
| Dnah12 |
C |
T |
14: 26,576,837 (GRCm39) |
T3029I |
probably damaging |
Het |
| Dppa3 |
A |
T |
6: 122,606,918 (GRCm39) |
Y136F |
probably damaging |
Het |
| Enox1 |
T |
A |
14: 77,958,284 (GRCm39) |
M611K |
probably benign |
Het |
| Fam149a |
A |
T |
8: 45,803,600 (GRCm39) |
I378N |
possibly damaging |
Het |
| Farp2 |
T |
C |
1: 93,488,040 (GRCm39) |
F89S |
probably damaging |
Het |
| Fbn2 |
C |
T |
18: 58,186,099 (GRCm39) |
V1750M |
probably benign |
Het |
| Frs3 |
A |
G |
17: 48,013,620 (GRCm39) |
T181A |
probably damaging |
Het |
| Heatr4 |
T |
A |
12: 84,004,644 (GRCm39) |
I726F |
possibly damaging |
Het |
| Ighg1 |
T |
G |
12: 113,290,216 (GRCm39) |
E375A |
|
Het |
| Ikzf4 |
G |
T |
10: 128,470,252 (GRCm39) |
Q476K |
possibly damaging |
Het |
| Kcnh1 |
G |
T |
1: 192,187,945 (GRCm39) |
C829F |
probably benign |
Het |
| Krtap19-4 |
T |
C |
16: 88,681,797 (GRCm39) |
Y53C |
unknown |
Het |
| Loricrin |
C |
A |
3: 91,988,705 (GRCm39) |
G194C |
unknown |
Het |
| Lrp1 |
A |
C |
10: 127,393,097 (GRCm39) |
D2720E |
probably benign |
Het |
| Lrp4 |
A |
G |
2: 91,322,368 (GRCm39) |
Y1068C |
probably damaging |
Het |
| Mbnl1 |
A |
G |
3: 60,511,244 (GRCm39) |
N67D |
probably benign |
Het |
| Mrpl21 |
A |
G |
19: 3,336,998 (GRCm39) |
E123G |
probably benign |
Het |
| Mst1 |
A |
T |
9: 107,958,485 (GRCm39) |
D65V |
probably damaging |
Het |
| Myo15b |
T |
A |
11: 115,767,921 (GRCm39) |
|
probably null |
Het |
| Myo5a |
A |
G |
9: 75,028,052 (GRCm39) |
Y79C |
probably damaging |
Het |
| Oas1c |
A |
T |
5: 120,940,957 (GRCm39) |
W279R |
probably damaging |
Het |
| Or4f4-ps1 |
A |
T |
2: 111,330,532 (GRCm39) |
M312L |
probably benign |
Het |
| Or4k77 |
A |
T |
2: 111,199,882 (GRCm39) |
I302L |
probably benign |
Het |
| Or51f5 |
A |
G |
7: 102,430,913 (GRCm39) |
I77V |
probably benign |
Het |
| Pcdh9 |
C |
T |
14: 93,253,216 (GRCm39) |
G1149D |
possibly damaging |
Het |
| Pcid2 |
G |
A |
8: 13,129,907 (GRCm39) |
T283I |
probably benign |
Het |
| Pdhx |
A |
G |
2: 102,858,760 (GRCm39) |
V348A |
probably benign |
Het |
| Pi16 |
C |
A |
17: 29,538,208 (GRCm39) |
P7Q |
possibly damaging |
Het |
| Psmb3 |
T |
A |
11: 97,602,023 (GRCm39) |
M131K |
probably null |
Het |
| Raph1 |
A |
G |
1: 60,542,032 (GRCm39) |
Y309H |
unknown |
Het |
| Rasgrf1 |
A |
G |
9: 89,866,341 (GRCm39) |
N593S |
probably damaging |
Het |
| Rbm38 |
A |
C |
2: 172,863,990 (GRCm39) |
E53A |
possibly damaging |
Het |
| Rufy3 |
A |
G |
5: 88,797,715 (GRCm39) |
T631A |
probably benign |
Het |
| Sbno1 |
A |
T |
5: 124,543,722 (GRCm39) |
D272E |
probably benign |
Het |
| Scamp1 |
T |
A |
13: 94,361,415 (GRCm39) |
Y207F |
probably damaging |
Het |
| Scn8a |
T |
A |
15: 100,866,984 (GRCm39) |
S263R |
probably damaging |
Het |
| Setbp1 |
T |
G |
18: 78,798,960 (GRCm39) |
T1407P |
probably damaging |
Het |
| Skor2 |
T |
C |
18: 76,948,096 (GRCm39) |
L606P |
possibly damaging |
Het |
| Slc35f6 |
A |
G |
5: 30,814,796 (GRCm39) |
N241S |
probably benign |
Het |
| Slc36a2 |
T |
G |
11: 55,059,744 (GRCm39) |
D247A |
probably benign |
Het |
| Smim10l1 |
T |
A |
6: 133,084,895 (GRCm39) |
F87L |
unknown |
Het |
| Son |
T |
C |
16: 91,461,889 (GRCm39) |
S2265P |
unknown |
Het |
| Spta1 |
A |
G |
1: 174,050,203 (GRCm39) |
N1748D |
probably damaging |
Het |
| Sptbn2 |
A |
G |
19: 4,774,201 (GRCm39) |
D84G |
probably damaging |
Het |
| Tasor2 |
T |
A |
13: 3,640,521 (GRCm39) |
L205F |
probably damaging |
Het |
| Tbc1d24 |
G |
A |
17: 24,404,266 (GRCm39) |
R293C |
probably damaging |
Het |
| Tex15 |
A |
G |
8: 34,036,268 (GRCm39) |
T65A |
probably benign |
Het |
| Thyn1 |
A |
G |
9: 26,916,506 (GRCm39) |
Y97C |
probably damaging |
Het |
| Tmem64 |
T |
C |
4: 15,266,700 (GRCm39) |
L250P |
probably damaging |
Het |
| Tnfrsf9 |
A |
T |
4: 151,019,991 (GRCm39) |
K217N |
probably damaging |
Het |
| Tnxb |
A |
G |
17: 34,898,039 (GRCm39) |
T896A |
probably benign |
Het |
| Trpm1 |
T |
A |
7: 63,854,333 (GRCm39) |
I285N |
possibly damaging |
Het |
| Try5 |
T |
A |
6: 41,288,637 (GRCm39) |
D194V |
probably damaging |
Het |
| U2surp |
G |
A |
9: 95,372,215 (GRCm39) |
R316* |
probably null |
Het |
| Ubr2 |
G |
T |
17: 47,246,360 (GRCm39) |
S1618* |
probably null |
Het |
| Ugp2 |
T |
C |
11: 21,273,271 (GRCm39) |
I449M |
probably damaging |
Het |
| Vmn2r31 |
C |
T |
7: 7,390,105 (GRCm39) |
V538I |
probably benign |
Het |
| Vmn2r31 |
A |
T |
7: 7,397,397 (GRCm39) |
M287K |
probably damaging |
Het |
| Wwc2 |
A |
G |
8: 48,311,919 (GRCm39) |
V748A |
unknown |
Het |
| Zfp800 |
A |
C |
6: 28,243,662 (GRCm39) |
H434Q |
probably benign |
Het |
| Zfp869 |
A |
G |
8: 70,159,356 (GRCm39) |
C406R |
probably damaging |
Het |
| Zhx1 |
A |
G |
15: 57,917,733 (GRCm39) |
V171A |
probably benign |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
31,215,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,205,478 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,227,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
31,187,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7231:Umodl1
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
31,217,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGTCAGTGTTACCATTCCTTG -3'
(R):5'- TGCGTCCTTGTTCCGAGTAC -3'
Sequencing Primer
(F):5'- GTCAGTGTTACCATTCCTTGTATAG -3'
(R):5'- TCCGAGTACTTGAGGGCAG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation