Mutagenetix > Incidental Mutation

Incidental Mutation 'R7260:Utp20'

564557

Institutional Source

Beutler Lab

Gene Symbol

Utp20

Ensembl Gene

ENSMUSG00000004356

Gene Name

UTP20 small subunit processome component

Synonyms

DRIM, 3830408P06Rik, mDRIM

MMRRC Submission

045352-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.962) question?

Stock #

R7260 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

88582469-88662666 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 88587334 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 2487 (I2487T)

Ref Sequence

ENSEMBL: ENSMUSP00000004470 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000004470]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000004470
AA Change: I2487T

PolyPhen 2 Score 0.390 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000004470
Gene: ENSMUSG00000004356
AA Change: I2487T

Domain	Start	End	E-Value	Type
low complexity region	244	255	N/A	INTRINSIC
low complexity region	442	454	N/A	INTRINSIC
low complexity region	571	581	N/A	INTRINSIC
low complexity region	695	704	N/A	INTRINSIC
Pfam:DRIM	910	1534	2.6e-176	PFAM
low complexity region	1585	1598	N/A	INTRINSIC
low complexity region	1705	1719	N/A	INTRINSIC
low complexity region	2503	2513	N/A	INTRINSIC
low complexity region	2589	2605	N/A	INTRINSIC
low complexity region	2727	2737	N/A	INTRINSIC
low complexity region	2746	2764	N/A	INTRINSIC

Meta Mutation Damage Score

0.4582

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

98% (78/80)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] UTP20 is a component of the U3 small nucleolar RNA (snoRNA) (SNORD3A; MIM 180710) protein complex (U3 snoRNP) and is involved in 18S rRNA processing (Wang et al., 2007 [PubMed 17498821]).[supplied by OMIM, Jun 2009]

Allele List at MGI

Other mutations in this stock

Total: 81 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310057J18Rik	A	G	10: 28,849,882 (GRCm39)	S293P	probably benign	Het
Actn2	T	C	13: 12,291,376 (GRCm39)	N676S	probably benign	Het
Amfr	C	T	8: 94,702,776 (GRCm39)	M463I	possibly damaging	Het
Ankdd1a	G	T	9: 65,411,834 (GRCm39)	A325D	probably damaging	Het
Apba2	A	G	7: 64,389,493 (GRCm39)	D463G	probably damaging	Het
Arid5b	A	G	10: 67,933,637 (GRCm39)	V755A	probably damaging	Het
Boc	A	T	16: 44,310,533 (GRCm39)	F796I		Het
Ccnt1	G	A	15: 98,463,005 (GRCm39)	Q56*	probably null	Het
Cd248	T	A	19: 5,119,383 (GRCm39)	Y410*	probably null	Het
Chd9	T	A	8: 91,721,171 (GRCm39)	N986K	unknown	Het
Col6a6	T	C	9: 105,661,168 (GRCm39)	T314A	probably benign	Het
Cpped1	A	G	16: 11,646,327 (GRCm39)	F142L	possibly damaging	Het
Csmd1	C	T	8: 16,050,574 (GRCm39)	A2221T	probably damaging	Het
Cyp2c69	C	A	19: 39,831,344 (GRCm39)	V490L	probably benign	Het
Cyrib	A	T	15: 63,829,438 (GRCm39)	F23L	possibly damaging	Het
Dcst2	T	C	3: 89,273,593 (GRCm39)	F157S	probably damaging	Het
Ddx54	G	T	5: 120,764,985 (GRCm39)	R788L	probably benign	Het
Dnah1	T	C	14: 30,991,343 (GRCm39)	Y3145C	probably damaging	Het
Dnah14	A	T	1: 181,534,309 (GRCm39)	R2320W	probably damaging	Het
Dnai3	T	A	3: 145,752,295 (GRCm39)	M794L	probably benign	Het
Emilin2	T	C	17: 71,581,785 (GRCm39)	T314A	probably benign	Het
Eml2	A	G	7: 18,934,515 (GRCm39)	S405G	probably benign	Het
Ephb2	A	G	4: 136,498,885 (GRCm39)	F65L	probably damaging	Het
Fbn2	T	C	18: 58,199,188 (GRCm39)	D1360G	probably benign	Het
Fbxo22	A	G	9: 55,125,754 (GRCm39)	T206A	probably benign	Het
Filip1l	A	G	16: 57,391,287 (GRCm39)	E625G	probably damaging	Het
Gen1	A	C	12: 11,306,849 (GRCm39)	M172R	probably damaging	Het
Gk5	A	G	9: 96,001,663 (GRCm39)	K54E	probably benign	Het
Glis3	T	C	19: 28,508,802 (GRCm39)	E394G	probably benign	Het
Helq	T	A	5: 100,939,793 (GRCm39)	E373D	probably damaging	Het
Ighv1-74	A	G	12: 115,766,372 (GRCm39)	F83L	probably benign	Het
Ints15	A	G	5: 143,297,594 (GRCm39)	V151A	probably benign	Het
Iqcn	T	C	8: 71,161,397 (GRCm39)	Y197H	probably benign	Het
Kdm4d	T	C	9: 14,374,454 (GRCm39)	D468G	probably benign	Het
Kif20b	A	G	19: 34,927,610 (GRCm39)	I957M	probably damaging	Het
Ldhal6b	A	G	17: 5,468,535 (GRCm39)	F133S	possibly damaging	Het
Loxhd1	T	C	18: 77,420,338 (GRCm39)	Y321H	possibly damaging	Het
Ltbp1	A	T	17: 75,373,139 (GRCm39)	M261L	probably benign	Het
Mical2	A	T	7: 111,919,001 (GRCm39)	Q430L	probably benign	Het
Mroh4	A	T	15: 74,479,978 (GRCm39)	N885K	possibly damaging	Het
Ms4a7	A	G	19: 11,299,710 (GRCm39)	Y231H	probably damaging	Het
Msh2	G	T	17: 88,025,047 (GRCm39)	V642F	probably damaging	Het
Muc5b	G	T	7: 141,396,385 (GRCm39)	A166S	unknown	Het
Myo18b	T	C	5: 112,923,154 (GRCm39)	I1868V	probably benign	Het
Nfatc3	T	C	8: 106,835,578 (GRCm39)	S975P	probably benign	Het
Oacyl	T	C	18: 65,831,438 (GRCm39)	L25P	probably damaging	Het
Or12e10	A	G	2: 87,640,731 (GRCm39)	N189S	probably damaging	Het
Or5b109	T	C	19: 13,212,388 (GRCm39)	F258S	probably damaging	Het
Or5w15	T	C	2: 87,568,852 (GRCm39)		probably null	Het
Or6c69	T	A	10: 129,748,156 (GRCm39)		probably benign	Het
Or8a1	T	A	9: 37,642,049 (GRCm39)	I77F	probably damaging	Het
Patj	A	G	4: 98,304,970 (GRCm39)	I275V	possibly damaging	Het
Pdcd11	G	A	19: 47,117,673 (GRCm39)	R1674Q	possibly damaging	Het
Peg10	CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG	CCACATCAGGATCCACATCAGGATGCACATCAG	6: 4,756,398 (GRCm39)		probably benign	Het
Phkb	T	A	8: 86,604,759 (GRCm39)	Y55N	probably benign	Het
Pias4	A	G	10: 80,993,302 (GRCm39)	V207A	possibly damaging	Het
Plxna4	C	A	6: 32,216,455 (GRCm39)	R540L	possibly damaging	Het
Psapl1	G	A	5: 36,362,556 (GRCm39)	V383M	probably benign	Het
Rars1	C	A	11: 35,725,281 (GRCm39)	A10S	probably benign	Het
Rhobtb1	A	T	10: 69,106,610 (GRCm39)	K454*	probably null	Het
Rmnd1	A	T	10: 4,364,803 (GRCm39)		probably null	Het
Rnf213	A	G	11: 119,343,401 (GRCm39)	I3589V		Het
Rngtt	T	C	4: 33,356,176 (GRCm39)	S338P	possibly damaging	Het
Sh3bgr	A	G	16: 96,025,681 (GRCm39)	E189G	unknown	Het
Slc30a3	G	A	5: 31,245,690 (GRCm39)	T281I	probably damaging	Het
Smok3c	T	A	5: 138,063,885 (GRCm39)	D457E	possibly damaging	Het
Stard9	C	A	2: 120,537,419 (GRCm39)	Q4274K	possibly damaging	Het
Syne2	G	T	12: 75,991,853 (GRCm39)	L1938F	probably damaging	Het
Tmem70	C	A	1: 16,735,590 (GRCm39)	T20K	possibly damaging	Het
Tnrc6a	A	G	7: 122,785,813 (GRCm39)	E1502G	probably benign	Het
Tpp1	A	T	7: 105,396,704 (GRCm39)	S438T	probably benign	Het
Tubb2a	T	A	13: 34,259,397 (GRCm39)	Q131L	probably damaging	Het
Ube2v1	A	G	2: 167,471,114 (GRCm39)	S26P	probably benign	Het
Unc13a	G	T	8: 72,113,229 (GRCm39)	S207R	possibly damaging	Het
Usp35	T	G	7: 96,969,286 (GRCm39)	D362A	probably damaging	Het
Vmn2r111	T	C	17: 22,778,032 (GRCm39)	N549S	possibly damaging	Het
Vmn2r117	T	A	17: 23,694,359 (GRCm39)	H496L	probably benign	Het
Vmn2r92	C	T	17: 18,387,138 (GRCm39)	A159V	probably damaging	Het
Wiz	T	C	17: 32,578,085 (GRCm39)	K467E	probably damaging	Het
Zfp534	T	C	4: 147,759,461 (GRCm39)	T403A	probably benign	Het
Zswim5	T	C	4: 116,819,843 (GRCm39)	L416P	probably damaging	Het

Other mutations in Utp20

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00530:Utp20	APN	10	88,661,306 (GRCm39)	missense	possibly damaging	0.90
IGL00858:Utp20	APN	10	88,644,987 (GRCm39)	missense	possibly damaging	0.69
IGL00858:Utp20	APN	10	88,645,000 (GRCm39)	missense	probably benign
IGL00946:Utp20	APN	10	88,584,177 (GRCm39)	missense	possibly damaging	0.82
IGL01061:Utp20	APN	10	88,606,566 (GRCm39)	missense	probably benign	0.13
IGL01399:Utp20	APN	10	88,594,164 (GRCm39)	critical splice donor site	probably null
IGL01548:Utp20	APN	10	88,600,643 (GRCm39)	missense	probably damaging	1.00
IGL01587:Utp20	APN	10	88,623,397 (GRCm39)	missense	probably damaging	0.98
IGL01789:Utp20	APN	10	88,634,141 (GRCm39)	critical splice donor site	probably null
IGL01819:Utp20	APN	10	88,628,549 (GRCm39)	missense	probably damaging	1.00
IGL02070:Utp20	APN	10	88,657,739 (GRCm39)	splice site	probably benign
IGL02231:Utp20	APN	10	88,627,030 (GRCm39)	missense	probably damaging	1.00
IGL02244:Utp20	APN	10	88,651,818 (GRCm39)	splice site	probably benign
IGL02367:Utp20	APN	10	88,607,715 (GRCm39)	unclassified	probably benign
IGL02553:Utp20	APN	10	88,600,657 (GRCm39)	missense	probably damaging	0.99
IGL02748:Utp20	APN	10	88,653,157 (GRCm39)	missense	probably benign	0.00
IGL02831:Utp20	APN	10	88,651,770 (GRCm39)	missense	probably benign
IGL02986:Utp20	APN	10	88,611,147 (GRCm39)	missense	probably damaging	1.00
IGL02997:Utp20	APN	10	88,649,896 (GRCm39)	missense	probably benign
IGL03105:Utp20	APN	10	88,626,958 (GRCm39)	missense	probably benign	0.10
IGL03251:Utp20	APN	10	88,653,188 (GRCm39)	critical splice acceptor site	probably null
IGL03337:Utp20	APN	10	88,590,428 (GRCm39)	missense	probably benign
IGL03348:Utp20	APN	10	88,594,179 (GRCm39)	missense	probably benign	0.09
IGL03381:Utp20	APN	10	88,657,867 (GRCm39)	missense	probably damaging	0.99
Bell	UTSW	10	88,628,487 (GRCm39)	missense	probably benign	0.29
elite	UTSW	10	88,606,670 (GRCm39)	missense	probably benign
Margin	UTSW	10	88,604,541 (GRCm39)	missense	probably benign	0.04
Percentile	UTSW	10	88,611,180 (GRCm39)	missense	probably damaging	1.00
R0037:Utp20	UTSW	10	88,634,266 (GRCm39)	missense	probably benign	0.05
R0107:Utp20	UTSW	10	88,614,253 (GRCm39)	missense	probably benign	0.03
R0197:Utp20	UTSW	10	88,613,378 (GRCm39)	missense	probably benign	0.22
R0219:Utp20	UTSW	10	88,600,537 (GRCm39)	missense	probably damaging	1.00
R0315:Utp20	UTSW	10	88,643,283 (GRCm39)	missense	probably damaging	1.00
R0328:Utp20	UTSW	10	88,602,969 (GRCm39)	missense	possibly damaging	0.82
R0329:Utp20	UTSW	10	88,653,841 (GRCm39)	missense	probably benign	0.00
R0330:Utp20	UTSW	10	88,653,841 (GRCm39)	missense	probably benign	0.00
R0395:Utp20	UTSW	10	88,654,457 (GRCm39)	missense	probably damaging	1.00
R0399:Utp20	UTSW	10	88,656,841 (GRCm39)	missense	probably damaging	1.00
R0454:Utp20	UTSW	10	88,657,931 (GRCm39)	missense	probably benign	0.00
R0456:Utp20	UTSW	10	88,590,435 (GRCm39)	missense	possibly damaging	0.92
R0491:Utp20	UTSW	10	88,596,774 (GRCm39)	missense	probably damaging	1.00
R0557:Utp20	UTSW	10	88,584,173 (GRCm39)	missense	probably damaging	0.99
R0600:Utp20	UTSW	10	88,603,323 (GRCm39)	missense	probably damaging	1.00
R0616:Utp20	UTSW	10	88,606,613 (GRCm39)	missense	probably benign	0.14
R1076:Utp20	UTSW	10	88,608,405 (GRCm39)	missense	possibly damaging	0.86
R1076:Utp20	UTSW	10	88,608,321 (GRCm39)	missense	probably benign	0.36
R1330:Utp20	UTSW	10	88,637,051 (GRCm39)	missense	probably damaging	0.96
R1440:Utp20	UTSW	10	88,655,201 (GRCm39)	missense	probably benign	0.19
R1529:Utp20	UTSW	10	88,588,868 (GRCm39)	missense	probably damaging	1.00
R1554:Utp20	UTSW	10	88,600,599 (GRCm39)	nonsense	probably null
R1621:Utp20	UTSW	10	88,598,733 (GRCm39)	missense	probably benign
R1641:Utp20	UTSW	10	88,593,834 (GRCm39)	missense	possibly damaging	0.82
R1709:Utp20	UTSW	10	88,585,159 (GRCm39)	missense	probably benign	0.29
R1734:Utp20	UTSW	10	88,603,323 (GRCm39)	missense	probably damaging	1.00
R1755:Utp20	UTSW	10	88,645,631 (GRCm39)	missense	probably benign	0.01
R1775:Utp20	UTSW	10	88,606,670 (GRCm39)	missense	probably benign
R1866:Utp20	UTSW	10	88,598,632 (GRCm39)	nonsense	probably null
R1867:Utp20	UTSW	10	88,585,305 (GRCm39)	missense	probably benign
R1901:Utp20	UTSW	10	88,588,888 (GRCm39)	missense	probably benign	0.02
R1902:Utp20	UTSW	10	88,588,888 (GRCm39)	missense	probably benign	0.02
R1967:Utp20	UTSW	10	88,652,841 (GRCm39)	missense	probably benign	0.03
R2060:Utp20	UTSW	10	88,610,657 (GRCm39)	missense	probably damaging	0.98
R2102:Utp20	UTSW	10	88,608,779 (GRCm39)	missense	probably damaging	0.99
R2110:Utp20	UTSW	10	88,603,313 (GRCm39)	critical splice donor site	probably null
R2115:Utp20	UTSW	10	88,621,865 (GRCm39)	missense	probably benign	0.02
R2128:Utp20	UTSW	10	88,649,917 (GRCm39)	missense	probably damaging	0.99
R2129:Utp20	UTSW	10	88,649,917 (GRCm39)	missense	probably damaging	0.99
R2180:Utp20	UTSW	10	88,656,801 (GRCm39)	missense	probably damaging	0.98
R2280:Utp20	UTSW	10	88,661,365 (GRCm39)	splice site	probably null
R2435:Utp20	UTSW	10	88,656,753 (GRCm39)	missense	possibly damaging	0.89
R2914:Utp20	UTSW	10	88,590,337 (GRCm39)	critical splice donor site	probably null
R3005:Utp20	UTSW	10	88,613,317 (GRCm39)	missense	probably damaging	0.97
R3546:Utp20	UTSW	10	88,618,551 (GRCm39)	missense	probably damaging	1.00
R3547:Utp20	UTSW	10	88,618,551 (GRCm39)	missense	probably damaging	1.00
R3622:Utp20	UTSW	10	88,593,855 (GRCm39)	unclassified	probably benign
R3737:Utp20	UTSW	10	88,598,668 (GRCm39)	missense	probably benign	0.00
R3738:Utp20	UTSW	10	88,598,668 (GRCm39)	missense	probably benign	0.00
R3841:Utp20	UTSW	10	88,611,065 (GRCm39)	unclassified	probably benign
R4034:Utp20	UTSW	10	88,598,668 (GRCm39)	missense	probably benign	0.00
R4035:Utp20	UTSW	10	88,598,668 (GRCm39)	missense	probably benign	0.00
R4157:Utp20	UTSW	10	88,597,729 (GRCm39)	missense	probably benign
R4243:Utp20	UTSW	10	88,643,187 (GRCm39)	critical splice donor site	probably null
R4295:Utp20	UTSW	10	88,590,381 (GRCm39)	missense	possibly damaging	0.54
R4632:Utp20	UTSW	10	88,614,123 (GRCm39)	missense	probably damaging	1.00
R4633:Utp20	UTSW	10	88,588,814 (GRCm39)	missense	probably benign
R4684:Utp20	UTSW	10	88,643,307 (GRCm39)	nonsense	probably null
R4731:Utp20	UTSW	10	88,590,382 (GRCm39)	missense	possibly damaging	0.93
R4735:Utp20	UTSW	10	88,652,780 (GRCm39)	missense	possibly damaging	0.91
R4772:Utp20	UTSW	10	88,645,797 (GRCm39)	missense	probably benign	0.09
R4912:Utp20	UTSW	10	88,607,822 (GRCm39)	missense	probably benign	0.01
R4974:Utp20	UTSW	10	88,652,811 (GRCm39)	missense	probably benign	0.08
R4991:Utp20	UTSW	10	88,582,796 (GRCm39)	missense	probably benign	0.09
R5004:Utp20	UTSW	10	88,584,135 (GRCm39)	missense	probably damaging	0.98
R5037:Utp20	UTSW	10	88,611,192 (GRCm39)	missense	probably benign	0.00
R5043:Utp20	UTSW	10	88,634,608 (GRCm39)	missense	possibly damaging	0.70
R5108:Utp20	UTSW	10	88,604,735 (GRCm39)	missense	probably benign	0.00
R5138:Utp20	UTSW	10	88,583,239 (GRCm39)	missense	probably damaging	0.96
R5252:Utp20	UTSW	10	88,586,532 (GRCm39)	missense	probably benign	0.01
R5394:Utp20	UTSW	10	88,608,777 (GRCm39)	nonsense	probably null
R5470:Utp20	UTSW	10	88,653,758 (GRCm39)	missense	probably benign	0.14
R5558:Utp20	UTSW	10	88,587,329 (GRCm39)	missense	probably damaging	1.00
R5678:Utp20	UTSW	10	88,644,979 (GRCm39)	missense	probably benign	0.00
R5822:Utp20	UTSW	10	88,653,147 (GRCm39)	missense	probably benign	0.00
R5866:Utp20	UTSW	10	88,608,421 (GRCm39)	missense	possibly damaging	0.82
R5924:Utp20	UTSW	10	88,651,784 (GRCm39)	missense	probably benign	0.00
R6026:Utp20	UTSW	10	88,604,541 (GRCm39)	missense	probably benign	0.04
R6363:Utp20	UTSW	10	88,592,942 (GRCm39)	missense	probably damaging	1.00
R6434:Utp20	UTSW	10	88,608,395 (GRCm39)	nonsense	probably null
R6477:Utp20	UTSW	10	88,604,780 (GRCm39)	missense	probably benign	0.05
R6480:Utp20	UTSW	10	88,591,048 (GRCm39)	critical splice donor site	probably null
R6989:Utp20	UTSW	10	88,614,102 (GRCm39)	missense	probably benign	0.00
R7033:Utp20	UTSW	10	88,590,337 (GRCm39)	critical splice donor site	probably null
R7192:Utp20	UTSW	10	88,608,321 (GRCm39)	missense	probably benign	0.09
R7236:Utp20	UTSW	10	88,585,204 (GRCm39)	missense	probably benign	0.28
R7296:Utp20	UTSW	10	88,606,586 (GRCm39)	missense	probably benign	0.21
R7317:Utp20	UTSW	10	88,598,797 (GRCm39)	missense	possibly damaging	0.83
R7318:Utp20	UTSW	10	88,649,811 (GRCm39)	missense	possibly damaging	0.89
R7330:Utp20	UTSW	10	88,623,424 (GRCm39)	frame shift	probably null
R7367:Utp20	UTSW	10	88,631,305 (GRCm39)	missense	probably benign	0.21
R7432:Utp20	UTSW	10	88,634,260 (GRCm39)	missense	probably benign	0.00
R7447:Utp20	UTSW	10	88,608,354 (GRCm39)	missense	probably damaging	1.00
R7473:Utp20	UTSW	10	88,656,572 (GRCm39)	splice site	probably null
R7520:Utp20	UTSW	10	88,654,457 (GRCm39)	missense	probably damaging	1.00
R7530:Utp20	UTSW	10	88,588,868 (GRCm39)	missense	probably damaging	1.00
R7539:Utp20	UTSW	10	88,627,607 (GRCm39)	missense	probably damaging	1.00
R7651:Utp20	UTSW	10	88,590,457 (GRCm39)	missense	probably benign	0.41
R7728:Utp20	UTSW	10	88,634,203 (GRCm39)	missense	probably damaging	1.00
R7831:Utp20	UTSW	10	88,598,632 (GRCm39)	nonsense	probably null
R7833:Utp20	UTSW	10	88,636,998 (GRCm39)	missense	possibly damaging	0.92
R7909:Utp20	UTSW	10	88,611,192 (GRCm39)	missense	probably benign
R7956:Utp20	UTSW	10	88,618,476 (GRCm39)	missense	probably benign	0.23
R7999:Utp20	UTSW	10	88,606,250 (GRCm39)	missense	probably benign
R8080:Utp20	UTSW	10	88,618,577 (GRCm39)	missense	possibly damaging	0.82
R8098:Utp20	UTSW	10	88,588,810 (GRCm39)	missense	probably benign	0.13
R8104:Utp20	UTSW	10	88,593,766 (GRCm39)	missense	probably damaging	1.00
R8129:Utp20	UTSW	10	88,628,487 (GRCm39)	missense	probably benign	0.29
R8147:Utp20	UTSW	10	88,594,306 (GRCm39)	missense	probably benign	0.02
R8199:Utp20	UTSW	10	88,634,337 (GRCm39)	missense	probably benign
R8222:Utp20	UTSW	10	88,614,234 (GRCm39)	missense	probably damaging	1.00
R8415:Utp20	UTSW	10	88,662,466 (GRCm39)	critical splice donor site	probably null
R8466:Utp20	UTSW	10	88,654,365 (GRCm39)	missense	probably damaging	1.00
R8505:Utp20	UTSW	10	88,653,870 (GRCm39)	missense	probably benign	0.03
R8774:Utp20	UTSW	10	88,588,763 (GRCm39)	splice site	probably benign
R8802:Utp20	UTSW	10	88,583,157 (GRCm39)	missense	probably damaging	1.00
R8923:Utp20	UTSW	10	88,627,604 (GRCm39)	nonsense	probably null
R8945:Utp20	UTSW	10	88,628,532 (GRCm39)	nonsense	probably null
R9065:Utp20	UTSW	10	88,592,972 (GRCm39)	missense	probably benign	0.32
R9092:Utp20	UTSW	10	88,611,180 (GRCm39)	missense	probably damaging	1.00
R9092:Utp20	UTSW	10	88,604,679 (GRCm39)	missense	probably benign
R9094:Utp20	UTSW	10	88,611,180 (GRCm39)	missense	probably damaging	1.00
R9095:Utp20	UTSW	10	88,611,180 (GRCm39)	missense	probably damaging	1.00
R9096:Utp20	UTSW	10	88,611,180 (GRCm39)	missense	probably damaging	1.00
R9229:Utp20	UTSW	10	88,594,239 (GRCm39)	missense	possibly damaging	0.86
R9323:Utp20	UTSW	10	88,583,170 (GRCm39)	missense	probably damaging	1.00
R9336:Utp20	UTSW	10	88,649,798 (GRCm39)	missense	probably damaging	1.00
R9467:Utp20	UTSW	10	88,640,390 (GRCm39)	missense	possibly damaging	0.68
R9545:Utp20	UTSW	10	88,618,511 (GRCm39)	missense	probably benign	0.38
R9659:Utp20	UTSW	10	88,653,171 (GRCm39)	missense	probably damaging	1.00
R9788:Utp20	UTSW	10	88,653,171 (GRCm39)	missense	probably damaging	1.00
RF005:Utp20	UTSW	10	88,661,319 (GRCm39)	missense	probably damaging	1.00
RF024:Utp20	UTSW	10	88,661,319 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GTCAGCTTGATTTTAGGCTAGCTAG -3'
(R):5'- TTCATAGGGAACGGTGGGAC -3'

Sequencing Primer
(F):5'- TGTTAGGAACCTGACTGC -3'
(R):5'- AAGCAGGGACCGTCATTTTC -3'

Posted On

2019-06-26