Mutagenetix > Incidental Mutation

Incidental Mutation 'R7270:Baz2b'

565206

Institutional Source

Beutler Lab

Gene Symbol

Baz2b

Ensembl Gene

ENSMUSG00000026987

Gene Name

bromodomain adjacent to zinc finger domain, 2B

Synonyms

D2Ertd794e, 5830435C13Rik

MMRRC Submission

045390-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.287) question?

Stock #

R7270 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

59729707-60040183 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 59792836 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Tyrosine at position 431 (N431Y)

Ref Sequence

ENSEMBL: ENSMUSP00000088443 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090925] [ENSMUST00000112550]

AlphaFold

A2AUY4

Predicted Effect

possibly damaging
Transcript: ENSMUST00000090925
AA Change: N431Y

PolyPhen 2 Score 0.956 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000088443
Gene: ENSMUSG00000026987
AA Change: N431Y

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	742	1e-12	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000112550
AA Change: N431Y

PolyPhen 2 Score 0.956 (Sensitivity: 0.79; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000108169
Gene: ENSMUSG00000026987
AA Change: N431Y

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	741	3.4e-13	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Pfam:WHIM3	1638	1676	5.1e-14	PFAM
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 72 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Afg1l	A	T	10: 42,301,245 (GRCm39)	Y193N	probably damaging	Het
Ahnak2	A	T	12: 112,780,802 (GRCm38)	V70E		Het
Aimp1	T	C	3: 132,382,772 (GRCm39)	K44E	probably damaging	Het
Arid1b	T	A	17: 5,046,318 (GRCm39)	Y369N	unknown	Het
Art5	A	T	7: 101,747,080 (GRCm39)	V233D	probably damaging	Het
Bik	T	A	15: 83,428,364 (GRCm39)	F131I	possibly damaging	Het
Bmpr1a	A	G	14: 34,163,082 (GRCm39)	Y103H	probably damaging	Het
Cabp7	C	T	11: 4,696,676 (GRCm39)	V18M	possibly damaging	Het
Cacna1a	C	A	8: 85,297,866 (GRCm39)	T1240N	probably damaging	Het
Cacna1h	A	G	17: 25,603,739 (GRCm39)	V1311A	probably damaging	Het
Cbarp	A	C	10: 79,973,151 (GRCm39)	S16A	possibly damaging	Het
Ccng2	C	G	5: 93,421,202 (GRCm39)	S237R	probably benign	Het
Ces2b	A	T	8: 105,564,472 (GRCm39)	H494L	possibly damaging	Het
Cfap43	T	A	19: 47,728,224 (GRCm39)	H1511L	possibly damaging	Het
Cfap54	A	G	10: 92,675,320 (GRCm39)	V2867A	probably benign	Het
Col5a1	C	T	2: 27,887,597 (GRCm39)	P956L	unknown	Het
Dcakd	T	G	11: 102,891,032 (GRCm39)	Q19P	possibly damaging	Het
Ddx47	T	A	6: 135,000,301 (GRCm39)	D432E	probably benign	Het
Dhrs7b	T	C	11: 60,735,055 (GRCm39)	F29L	probably benign	Het
Dis3l2	A	T	1: 86,918,025 (GRCm39)	D558V	possibly damaging	Het
Dtx3l	T	A	16: 35,754,027 (GRCm39)	D193V	probably damaging	Het
Eif1ad12	T	C	12: 87,541,663 (GRCm39)	L58P	probably damaging	Het
Epha4	G	A	1: 77,376,422 (GRCm39)	R486C	probably damaging	Het
Fam186a	T	C	15: 99,842,033 (GRCm39)	T1404A	possibly damaging	Het
Fat1	A	G	8: 45,490,475 (GRCm39)	T3796A	probably damaging	Het
Ffar2	A	T	7: 30,518,929 (GRCm39)	W204R	probably benign	Het
Ftmt	A	G	18: 52,465,091 (GRCm39)	I136V	probably benign	Het
Gm10300	T	C	4: 131,802,167 (GRCm39)	W54R	unknown	Het
Gm10518	C	T	1: 179,630,949 (GRCm39)	P3L	unknown	Het
Grm2	G	A	9: 106,528,257 (GRCm39)	T209M	probably damaging	Het
Gtdc1	C	T	2: 44,525,322 (GRCm39)	M176I	probably benign	Het
Insrr	T	C	3: 87,710,440 (GRCm39)	L382P	probably damaging	Het
Jade2	A	G	11: 51,708,011 (GRCm39)	V734A	possibly damaging	Het
Kcnh4	C	T	11: 100,638,472 (GRCm39)	R586H	probably benign	Het
Kdm1a	A	T	4: 136,279,838 (GRCm39)	D721E	probably damaging	Het
Knl1	G	A	2: 118,933,003 (GRCm39)	C2054Y	possibly damaging	Het
Lrrk2	C	T	15: 91,584,644 (GRCm39)	P354S	probably benign	Het
Luzp2	A	G	7: 54,724,774 (GRCm39)	I112V	probably damaging	Het
Mgl2	T	C	11: 70,026,506 (GRCm39)	S105P	probably damaging	Het
Mocs1	T	A	17: 49,756,143 (GRCm39)	M200K	possibly damaging	Het
Oat	T	A	7: 132,168,927 (GRCm39)	I98L	probably benign	Het
Obscn	T	C	11: 58,920,312 (GRCm39)	Y8C		Het
Or5b108	G	A	19: 13,168,768 (GRCm39)	V246I	possibly damaging	Het
Or6c1b	T	G	10: 129,273,319 (GRCm39)	F213V	probably benign	Het
Pde1b	T	A	15: 103,430,082 (GRCm39)	M137K	possibly damaging	Het
Phf21a	T	C	2: 92,157,484 (GRCm39)	I204T	probably damaging	Het
Plcd4	A	G	1: 74,593,838 (GRCm39)	E321G	possibly damaging	Het
Plpp7	C	T	2: 31,985,662 (GRCm39)		probably benign	Het
Prdm1	A	G	10: 44,317,566 (GRCm39)	I419T	probably benign	Het
Sec16b	A	T	1: 157,392,032 (GRCm39)	R855W	probably damaging	Het
Sec16b	G	T	1: 157,392,033 (GRCm39)	R855M	probably damaging	Het
Sec31b	T	C	19: 44,511,482 (GRCm39)	T640A	probably benign	Het
Siglec1	T	C	2: 130,923,471 (GRCm39)	T425A	possibly damaging	Het
Sirpd	A	T	3: 15,385,704 (GRCm39)	I66N	probably benign	Het
Skil	T	C	3: 31,151,324 (GRCm39)		probably benign	Het
Slc1a5	G	A	7: 16,519,623 (GRCm39)	V200M	probably damaging	Het
Slc25a12	T	C	2: 71,154,369 (GRCm39)	H139R	probably benign	Het
Slc25a32	A	T	15: 38,961,630 (GRCm39)	V187D	probably damaging	Het
Slc35a3	G	A	3: 116,505,455 (GRCm39)		probably benign	Het
Smap2	C	A	4: 120,829,264 (GRCm39)	M328I	probably benign	Het
Spef2	C	T	15: 9,600,066 (GRCm39)		probably null	Het
Srarp	A	G	4: 141,160,389 (GRCm39)	V148A	possibly damaging	Het
Stard9	T	A	2: 120,464,755 (GRCm39)	Y73*	probably null	Het
Tars1	A	G	15: 11,392,105 (GRCm39)	C236R	probably benign	Het
Tchh	G	C	3: 93,351,837 (GRCm39)	D426H	unknown	Het
Tnks2	T	C	19: 36,836,545 (GRCm39)	F17S		Het
Ube2g1	T	C	11: 72,553,939 (GRCm39)	I30T	possibly damaging	Het
Ube2o	C	T	11: 116,434,761 (GRCm39)	D567N	possibly damaging	Het
Unc5b	A	T	10: 60,608,002 (GRCm39)	Y710*	probably null	Het
Vmn1r215	T	C	13: 23,260,089 (GRCm39)	V43A	possibly damaging	Het
Xkr8	A	G	4: 132,455,648 (GRCm39)	F242L	probably benign	Het
Zfp526	T	A	7: 24,925,345 (GRCm39)	C535S	probably damaging	Het

Other mutations in Baz2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00430:Baz2b	APN	2	59,743,139 (GRCm39)	missense	probably benign	0.02
IGL00476:Baz2b	APN	2	59,744,083 (GRCm39)	missense	probably benign	0.06
IGL00489:Baz2b	APN	2	59,788,019 (GRCm39)	nonsense	probably null
IGL00514:Baz2b	APN	2	59,792,821 (GRCm39)	missense	probably benign	0.11
IGL00678:Baz2b	APN	2	59,836,527 (GRCm39)	missense	unknown
IGL01348:Baz2b	APN	2	59,764,031 (GRCm39)	missense	possibly damaging	0.95
IGL01354:Baz2b	APN	2	59,799,233 (GRCm39)	missense	probably benign	0.18
IGL01924:Baz2b	APN	2	59,765,615 (GRCm39)	missense	probably damaging	1.00
IGL02125:Baz2b	APN	2	59,798,984 (GRCm39)	missense	probably benign	0.12
IGL02314:Baz2b	APN	2	59,792,571 (GRCm39)	missense	probably benign
IGL02370:Baz2b	APN	2	59,753,933 (GRCm39)	missense	possibly damaging	0.77
IGL02473:Baz2b	APN	2	59,790,407 (GRCm39)	missense	probably benign	0.40
IGL02499:Baz2b	APN	2	59,731,840 (GRCm39)	missense	possibly damaging	0.60
IGL02609:Baz2b	APN	2	59,747,713 (GRCm39)	missense	possibly damaging	0.77
IGL02705:Baz2b	APN	2	59,778,604 (GRCm39)	missense	possibly damaging	0.92
IGL02711:Baz2b	APN	2	59,747,849 (GRCm39)	unclassified	probably benign
IGL02716:Baz2b	APN	2	59,792,868 (GRCm39)	missense	possibly damaging	0.53
IGL02724:Baz2b	APN	2	59,807,718 (GRCm39)	missense	possibly damaging	0.70
IGL02750:Baz2b	APN	2	59,799,002 (GRCm39)	missense	possibly damaging	0.73
IGL02869:Baz2b	APN	2	59,807,872 (GRCm39)	missense	probably benign	0.00
IGL02886:Baz2b	APN	2	59,788,087 (GRCm39)	splice site	probably null
IGL02892:Baz2b	APN	2	59,731,080 (GRCm39)	missense	probably damaging	1.00
IGL03132:Baz2b	APN	2	59,738,097 (GRCm39)	splice site	probably benign
IGL03183:Baz2b	APN	2	59,733,640 (GRCm39)	missense	probably benign	0.10
IGL03197:Baz2b	APN	2	59,731,898 (GRCm39)	missense	possibly damaging	0.74
R0054:Baz2b	UTSW	2	59,762,510 (GRCm39)	missense	probably damaging	1.00
R0054:Baz2b	UTSW	2	59,762,510 (GRCm39)	missense	probably damaging	1.00
R0122:Baz2b	UTSW	2	59,743,963 (GRCm39)	splice site	probably null
R0136:Baz2b	UTSW	2	59,732,298 (GRCm39)	missense	probably benign	0.22
R0144:Baz2b	UTSW	2	59,737,839 (GRCm39)	missense	probably damaging	0.98
R0403:Baz2b	UTSW	2	59,799,721 (GRCm39)	missense	possibly damaging	0.70
R0498:Baz2b	UTSW	2	59,732,340 (GRCm39)	unclassified	probably benign
R0528:Baz2b	UTSW	2	59,767,083 (GRCm39)	missense	probably damaging	1.00
R1025:Baz2b	UTSW	2	59,792,826 (GRCm39)	missense	probably benign	0.06
R1470:Baz2b	UTSW	2	59,808,890 (GRCm39)	missense	possibly damaging	0.53
R1470:Baz2b	UTSW	2	59,808,890 (GRCm39)	missense	possibly damaging	0.53
R1510:Baz2b	UTSW	2	59,752,553 (GRCm39)	missense	probably damaging	1.00
R1511:Baz2b	UTSW	2	59,792,368 (GRCm39)	missense	probably benign	0.12
R1514:Baz2b	UTSW	2	59,792,670 (GRCm39)	missense	probably benign	0.13
R1519:Baz2b	UTSW	2	59,778,598 (GRCm39)	missense	possibly damaging	0.50
R1523:Baz2b	UTSW	2	59,798,981 (GRCm39)	missense	possibly damaging	0.47
R1630:Baz2b	UTSW	2	59,836,474 (GRCm39)	missense	unknown
R1641:Baz2b	UTSW	2	59,743,234 (GRCm39)	missense	probably damaging	0.99
R1674:Baz2b	UTSW	2	59,743,336 (GRCm39)	missense	possibly damaging	0.53
R1778:Baz2b	UTSW	2	59,836,480 (GRCm39)	missense	unknown
R1826:Baz2b	UTSW	2	59,799,077 (GRCm39)	missense	probably benign	0.12
R1835:Baz2b	UTSW	2	59,732,163 (GRCm39)	missense	probably benign	0.02
R1954:Baz2b	UTSW	2	59,799,087 (GRCm39)	missense	probably benign	0.12
R1981:Baz2b	UTSW	2	59,754,024 (GRCm39)	missense	possibly damaging	0.95
R2029:Baz2b	UTSW	2	59,743,067 (GRCm39)	unclassified	probably benign
R2567:Baz2b	UTSW	2	59,744,255 (GRCm39)	missense	possibly damaging	0.82
R2842:Baz2b	UTSW	2	59,743,348 (GRCm39)	missense	probably benign	0.27
R2848:Baz2b	UTSW	2	59,755,010 (GRCm39)	missense	possibly damaging	0.64
R3809:Baz2b	UTSW	2	59,799,240 (GRCm39)	missense	probably benign	0.12
R3935:Baz2b	UTSW	2	59,743,105 (GRCm39)	missense	possibly damaging	0.81
R3936:Baz2b	UTSW	2	59,743,105 (GRCm39)	missense	possibly damaging	0.81
R4072:Baz2b	UTSW	2	59,742,917 (GRCm39)	splice site	probably null
R4182:Baz2b	UTSW	2	59,928,801 (GRCm39)	intron	probably benign
R4255:Baz2b	UTSW	2	59,750,916 (GRCm39)	unclassified	probably benign
R4359:Baz2b	UTSW	2	59,731,957 (GRCm39)	missense	possibly damaging	0.87
R4716:Baz2b	UTSW	2	59,799,599 (GRCm39)	missense	probably benign	0.06
R4743:Baz2b	UTSW	2	59,744,255 (GRCm39)	missense	probably benign	0.01
R4772:Baz2b	UTSW	2	59,788,795 (GRCm39)	missense	probably damaging	0.96
R4858:Baz2b	UTSW	2	59,738,087 (GRCm39)	missense	probably benign
R4868:Baz2b	UTSW	2	59,755,226 (GRCm39)	missense	possibly damaging	0.65
R4872:Baz2b	UTSW	2	59,773,103 (GRCm39)	splice site	probably null
R4889:Baz2b	UTSW	2	59,767,070 (GRCm39)	missense	probably damaging	1.00
R4890:Baz2b	UTSW	2	59,756,383 (GRCm39)	missense	probably damaging	0.99
R4914:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R4915:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R4918:Baz2b	UTSW	2	59,744,387 (GRCm39)	missense	possibly damaging	0.70
R5027:Baz2b	UTSW	2	59,928,988 (GRCm39)	intron	probably benign
R5031:Baz2b	UTSW	2	59,743,151 (GRCm39)	missense	probably benign	0.00
R5082:Baz2b	UTSW	2	59,731,835 (GRCm39)	nonsense	probably null
R5133:Baz2b	UTSW	2	59,792,368 (GRCm39)	missense	probably benign	0.12
R5276:Baz2b	UTSW	2	59,792,958 (GRCm39)	missense	probably benign	0.40
R5279:Baz2b	UTSW	2	59,762,496 (GRCm39)	missense	probably damaging	1.00
R5294:Baz2b	UTSW	2	59,808,946 (GRCm39)	missense	probably benign	0.11
R5447:Baz2b	UTSW	2	59,744,332 (GRCm39)	missense	probably damaging	0.99
R5903:Baz2b	UTSW	2	59,790,233 (GRCm39)	missense	probably damaging	0.99
R5910:Baz2b	UTSW	2	59,807,770 (GRCm39)	missense	possibly damaging	0.88
R6140:Baz2b	UTSW	2	59,742,871 (GRCm39)	missense	probably damaging	0.99
R6195:Baz2b	UTSW	2	59,737,855 (GRCm39)	missense	possibly damaging	0.89
R6199:Baz2b	UTSW	2	59,809,019 (GRCm39)	missense	probably benign	0.00
R6208:Baz2b	UTSW	2	59,755,150 (GRCm39)	missense	probably damaging	1.00
R6233:Baz2b	UTSW	2	59,737,855 (GRCm39)	missense	possibly damaging	0.89
R6276:Baz2b	UTSW	2	59,778,567 (GRCm39)	missense	probably damaging	1.00
R6324:Baz2b	UTSW	2	59,737,292 (GRCm39)	missense	probably damaging	1.00
R6490:Baz2b	UTSW	2	59,732,073 (GRCm39)	missense	probably damaging	1.00
R6578:Baz2b	UTSW	2	59,799,623 (GRCm39)	missense	possibly damaging	0.47
R6720:Baz2b	UTSW	2	59,755,234 (GRCm39)	missense	probably damaging	1.00
R6760:Baz2b	UTSW	2	59,792,776 (GRCm39)	missense	probably benign	0.40
R6836:Baz2b	UTSW	2	59,747,769 (GRCm39)	missense	probably damaging	1.00
R6859:Baz2b	UTSW	2	59,731,874 (GRCm39)	missense	probably benign	0.01
R6880:Baz2b	UTSW	2	59,743,283 (GRCm39)	missense	probably damaging	0.99
R6916:Baz2b	UTSW	2	59,799,120 (GRCm39)	missense	probably benign
R6978:Baz2b	UTSW	2	59,738,059 (GRCm39)	missense	possibly damaging	0.84
R7037:Baz2b	UTSW	2	59,764,014 (GRCm39)	critical splice donor site	probably null
R7112:Baz2b	UTSW	2	59,792,528 (GRCm39)	missense	possibly damaging	0.53
R7117:Baz2b	UTSW	2	59,742,841 (GRCm39)	missense
R7198:Baz2b	UTSW	2	59,792,550 (GRCm39)	missense	probably benign	0.00
R7282:Baz2b	UTSW	2	59,750,781 (GRCm39)	missense	probably benign	0.17
R7464:Baz2b	UTSW	2	59,807,792 (GRCm39)	missense	possibly damaging	0.53
R7609:Baz2b	UTSW	2	59,792,817 (GRCm39)	missense	probably benign	0.40
R7703:Baz2b	UTSW	2	59,747,769 (GRCm39)	missense	probably damaging	1.00
R7850:Baz2b	UTSW	2	59,767,060 (GRCm39)	missense	probably damaging	0.98
R7851:Baz2b	UTSW	2	59,767,060 (GRCm39)	missense	probably damaging	0.98
R7988:Baz2b	UTSW	2	59,792,485 (GRCm39)	missense	possibly damaging	0.53
R8079:Baz2b	UTSW	2	59,731,112 (GRCm39)	missense	probably damaging	1.00
R8084:Baz2b	UTSW	2	59,792,580 (GRCm39)	missense	probably benign
R8343:Baz2b	UTSW	2	59,731,858 (GRCm39)	missense	probably damaging	1.00
R8348:Baz2b	UTSW	2	59,742,137 (GRCm39)	missense
R8438:Baz2b	UTSW	2	59,747,828 (GRCm39)	nonsense	probably null
R8448:Baz2b	UTSW	2	59,742,137 (GRCm39)	missense
R8511:Baz2b	UTSW	2	59,732,158 (GRCm39)	missense	probably benign
R8893:Baz2b	UTSW	2	59,755,149 (GRCm39)	missense	probably damaging	0.96
R8947:Baz2b	UTSW	2	59,778,583 (GRCm39)	missense	probably benign	0.06
R8998:Baz2b	UTSW	2	59,799,608 (GRCm39)	missense	probably benign	0.02
R9241:Baz2b	UTSW	2	59,743,993 (GRCm39)	missense	probably benign	0.01
R9245:Baz2b	UTSW	2	59,743,331 (GRCm39)	missense	probably benign
R9577:Baz2b	UTSW	2	59,809,031 (GRCm39)	missense	probably benign	0.06
R9581:Baz2b	UTSW	2	59,799,300 (GRCm39)	missense	probably benign
R9601:Baz2b	UTSW	2	59,731,847 (GRCm39)	missense	possibly damaging	0.66
R9613:Baz2b	UTSW	2	59,731,824 (GRCm39)	missense	probably benign	0.09
R9639:Baz2b	UTSW	2	59,731,828 (GRCm39)	missense	probably benign	0.01
X0011:Baz2b	UTSW	2	59,807,705 (GRCm39)	missense	possibly damaging	0.53
X0053:Baz2b	UTSW	2	59,731,019 (GRCm39)	missense	probably damaging	1.00
X0064:Baz2b	UTSW	2	59,799,626 (GRCm39)	missense	probably benign
Z1088:Baz2b	UTSW	2	59,790,359 (GRCm39)	missense	probably damaging	1.00
Z1177:Baz2b	UTSW	2	59,807,864 (GRCm39)	missense	probably benign	0.01
Z1188:Baz2b	UTSW	2	59,807,749 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TGCTCAGATTGACAGGTGAGG -3'
(R):5'- GGACAGCTGTGTTCTGATACTG -3'

Sequencing Primer
(F):5'- GAGAACGGGGTGCTACTTG -3'
(R):5'- CAGCTGTGTTCTGATACTGACAAAC -3'

Posted On

2019-06-26