Incidental Mutation 'R7310:Itga10'
| ID |
567482 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Itga10
|
| Ensembl Gene |
ENSMUSG00000090210 |
| Gene Name |
integrin, alpha 10 |
| Synonyms |
|
| MMRRC Submission |
045409-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.150)
|
| Stock # |
R7310 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
96552900-96571835 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 96555475 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Aspartic acid
at position 143
(A143D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112393
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029744]
[ENSMUST00000048766]
[ENSMUST00000118557]
[ENSMUST00000119365]
[ENSMUST00000137564]
[ENSMUST00000156015]
[ENSMUST00000165842]
|
| AlphaFold |
E9Q6R1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029744
AA Change: A143D
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000029744
Gene: ENSMUSG00000090210
AA Change: A143D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Int_alpha
|
37 |
93 |
9.03e-3 |
SMART |
|
VWA
|
165 |
355 |
9.6e-43 |
SMART |
|
Int_alpha
|
427 |
481 |
2.01e0 |
SMART |
|
Int_alpha
|
482 |
539 |
5.14e-7 |
SMART |
|
Int_alpha
|
545 |
600 |
5.34e-14 |
SMART |
|
Int_alpha
|
607 |
652 |
8.75e0 |
SMART |
|
transmembrane domain
|
1123 |
1145 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1166 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000048766
|
| SMART Domains |
Protein: ENSMUSP00000037962
Gene: ENSMUSG00000028102
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PEX11
|
1 |
251 |
1.9e-76 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000118557
|
| SMART Domains |
Protein: ENSMUSP00000113365
Gene: ENSMUSG00000028102
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PEX11
|
1 |
251 |
8.3e-77 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000119365
AA Change: A143D
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000112393
Gene: ENSMUSG00000090210
AA Change: A143D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Int_alpha
|
37 |
93 |
9.03e-3 |
SMART |
|
VWA
|
165 |
355 |
9.6e-43 |
SMART |
|
Int_alpha
|
427 |
481 |
2.01e0 |
SMART |
|
Int_alpha
|
482 |
539 |
5.14e-7 |
SMART |
|
Int_alpha
|
545 |
600 |
5.34e-14 |
SMART |
|
Int_alpha
|
607 |
652 |
8.75e0 |
SMART |
|
transmembrane domain
|
1122 |
1144 |
N/A |
INTRINSIC |
|
low complexity region
|
1152 |
1165 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000137564
AA Change: A328D
|
| SMART Domains |
Protein: ENSMUSP00000121011
Gene: ENSMUSG00000106447
AA Change: A328D
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PEX11
|
1 |
172 |
4.5e-57 |
PFAM |
|
low complexity region
|
186 |
204 |
N/A |
INTRINSIC |
|
Int_alpha
|
222 |
278 |
9.03e-3 |
SMART |
|
Blast:VWA
|
292 |
345 |
3e-7 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156015
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165842
|
| SMART Domains |
Protein: ENSMUSP00000126631
Gene: ENSMUSG00000028102
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PEX11
|
3 |
237 |
8.9e-69 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Integrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell-surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP-2epsilon and Ets-1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
PHENOTYPE: Homozygous null mice display slightly shortened long bones and amild abnormalities in ephysiseal plate morphology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810021J22Rik |
A |
T |
11: 58,771,094 (GRCm39) |
Q192L |
possibly damaging |
Het |
| Abat |
G |
A |
16: 8,423,457 (GRCm39) |
R250Q |
probably null |
Het |
| Abcg3 |
A |
C |
5: 105,114,632 (GRCm39) |
F295C |
probably benign |
Het |
| Abl1 |
T |
C |
2: 31,690,604 (GRCm39) |
S708P |
possibly damaging |
Het |
| Acap2 |
A |
T |
16: 30,926,972 (GRCm39) |
Y489* |
probably null |
Het |
| Akr1c6 |
A |
T |
13: 4,486,354 (GRCm39) |
M54L |
probably benign |
Het |
| Arhgap5 |
A |
T |
12: 52,589,270 (GRCm39) |
|
probably null |
Het |
| Asap1 |
A |
G |
15: 63,971,379 (GRCm39) |
|
probably null |
Het |
| Atrnl1 |
A |
T |
19: 57,630,856 (GRCm39) |
N208Y |
possibly damaging |
Het |
| BC028528 |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
3: 95,795,448 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
GTTCTGTGGTCACTG |
GTTCTGTGGTCACTGATTCTGTGGTCACTG |
3: 95,795,485 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
G |
GGGGTCACTGGTTCTT |
3: 95,795,460 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
ACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC |
ACTGGTTCTGTGGTCCCTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC |
3: 95,795,451 (GRCm39) |
|
probably benign |
Het |
| Bmi1 |
T |
C |
2: 18,689,230 (GRCm39) |
S305P |
probably benign |
Het |
| Bpifc |
T |
A |
10: 85,798,891 (GRCm39) |
I431F |
probably damaging |
Het |
| C130050O18Rik |
A |
T |
5: 139,400,993 (GRCm39) |
M349L |
probably benign |
Het |
| Cacna2d1 |
A |
T |
5: 16,519,914 (GRCm39) |
D428V |
probably damaging |
Het |
| Card14 |
A |
C |
11: 119,217,005 (GRCm39) |
Q363P |
probably null |
Het |
| Cdca2 |
A |
T |
14: 67,950,673 (GRCm39) |
L86H |
probably damaging |
Het |
| Cdh22 |
G |
T |
2: 164,954,214 (GRCm39) |
S769* |
probably null |
Het |
| Cdhr17 |
A |
G |
5: 17,075,246 (GRCm39) |
Y872C |
possibly damaging |
Het |
| Cep164 |
T |
C |
9: 45,686,664 (GRCm39) |
E690G |
probably damaging |
Het |
| Cluh |
A |
G |
11: 74,560,285 (GRCm39) |
H1304R |
probably benign |
Het |
| Daxx |
C |
A |
17: 34,129,435 (GRCm39) |
D5E |
possibly damaging |
Het |
| Dnah7c |
A |
G |
1: 46,636,127 (GRCm39) |
M1117V |
possibly damaging |
Het |
| Entpd3 |
T |
A |
9: 120,389,821 (GRCm39) |
|
probably null |
Het |
| Esr1 |
G |
A |
10: 4,889,259 (GRCm39) |
A386T |
probably damaging |
Het |
| Etv5 |
G |
A |
16: 22,220,487 (GRCm39) |
P300L |
probably benign |
Het |
| Exoc3l |
A |
T |
8: 106,020,340 (GRCm39) |
L195Q |
probably damaging |
Het |
| Exog |
T |
C |
9: 119,274,069 (GRCm39) |
L18P |
unknown |
Het |
| Fgfr1 |
T |
A |
8: 26,052,331 (GRCm39) |
V219D |
probably benign |
Het |
| Gna14 |
A |
T |
19: 16,511,113 (GRCm39) |
Q54L |
|
Het |
| Gnb5 |
T |
C |
9: 75,221,570 (GRCm39) |
L48P |
probably benign |
Het |
| Gpbp1 |
A |
G |
13: 111,589,924 (GRCm39) |
I57T |
probably benign |
Het |
| Hnrnpa1 |
T |
A |
15: 103,149,884 (GRCm39) |
D48E |
probably damaging |
Het |
| Hrc |
T |
A |
7: 44,985,227 (GRCm39) |
L126* |
probably null |
Het |
| Hspa8 |
T |
G |
9: 40,714,704 (GRCm39) |
D333E |
probably benign |
Het |
| Igsf3 |
T |
A |
3: 101,338,895 (GRCm39) |
V403D |
probably benign |
Het |
| Kdr |
T |
A |
5: 76,104,985 (GRCm39) |
I1082F |
probably damaging |
Het |
| Klk1b11 |
A |
T |
7: 43,428,254 (GRCm39) |
I242F |
probably damaging |
Het |
| Kng2 |
G |
A |
16: 22,806,522 (GRCm39) |
T559I |
probably benign |
Het |
| Map1b |
G |
A |
13: 99,570,163 (GRCm39) |
P853S |
unknown |
Het |
| Mmp13 |
T |
C |
9: 7,280,880 (GRCm39) |
I421T |
possibly damaging |
Het |
| Mpeg1 |
A |
T |
19: 12,439,615 (GRCm39) |
T358S |
probably damaging |
Het |
| Msantd5l |
A |
C |
11: 51,145,474 (GRCm39) |
W38G |
probably damaging |
Het |
| Mttp |
T |
C |
3: 137,800,783 (GRCm39) |
D759G |
probably damaging |
Het |
| Mup17 |
T |
A |
4: 61,511,929 (GRCm39) |
Y115F |
possibly damaging |
Het |
| Myo1a |
G |
T |
10: 127,541,697 (GRCm39) |
A79S |
probably damaging |
Het |
| Myo9a |
T |
A |
9: 59,778,436 (GRCm39) |
N1397K |
probably benign |
Het |
| Nadk2 |
T |
C |
15: 9,103,469 (GRCm39) |
|
probably null |
Het |
| Ncf1 |
A |
T |
5: 134,250,615 (GRCm39) |
S402T |
probably benign |
Het |
| Ndufb10 |
T |
C |
17: 24,941,188 (GRCm39) |
D145G |
probably damaging |
Het |
| Nlgn2 |
G |
A |
11: 69,721,409 (GRCm39) |
T163M |
possibly damaging |
Het |
| Nol4 |
A |
T |
18: 22,903,801 (GRCm39) |
H172Q |
|
Het |
| Nup205 |
T |
A |
6: 35,202,904 (GRCm39) |
D1370E |
possibly damaging |
Het |
| Or1e32 |
A |
C |
11: 73,705,112 (GRCm39) |
N265K |
probably damaging |
Het |
| Or51ab3 |
T |
A |
7: 103,201,892 (GRCm39) |
I300N |
probably damaging |
Het |
| Or5b97 |
A |
G |
19: 12,878,637 (GRCm39) |
F169S |
probably damaging |
Het |
| Pkd1l2 |
A |
G |
8: 117,750,773 (GRCm39) |
V1746A |
probably benign |
Het |
| Plin2 |
T |
A |
4: 86,586,628 (GRCm39) |
I68F |
probably benign |
Het |
| Proc |
A |
T |
18: 32,268,952 (GRCm39) |
M11K |
probably benign |
Het |
| Rif1 |
T |
C |
2: 51,995,631 (GRCm39) |
V950A |
probably benign |
Het |
| Rmc1 |
A |
G |
18: 12,317,972 (GRCm39) |
K362E |
probably benign |
Het |
| Rnf208 |
C |
A |
2: 25,133,587 (GRCm39) |
P94T |
probably damaging |
Het |
| Rundc3b |
A |
T |
5: 8,571,011 (GRCm39) |
Y269* |
probably null |
Het |
| Senp7 |
T |
C |
16: 56,006,445 (GRCm39) |
V950A |
probably benign |
Het |
| Sipa1l1 |
T |
C |
12: 82,419,269 (GRCm39) |
V649A |
probably damaging |
Het |
| Sipa1l3 |
G |
T |
7: 29,099,121 (GRCm39) |
H383N |
probably benign |
Het |
| Slc12a5 |
G |
A |
2: 164,834,360 (GRCm39) |
V794M |
probably damaging |
Het |
| Slc7a7 |
A |
G |
14: 54,616,482 (GRCm39) |
I200T |
probably damaging |
Het |
| Spdye4b |
A |
C |
5: 143,188,103 (GRCm39) |
I199L |
probably damaging |
Het |
| Styxl2 |
G |
A |
1: 165,926,300 (GRCm39) |
T1104I |
possibly damaging |
Het |
| Tle4 |
A |
T |
19: 14,495,155 (GRCm39) |
H191Q |
probably benign |
Het |
| Tnfsf13b |
C |
A |
8: 10,081,651 (GRCm39) |
S271* |
probably null |
Het |
| Tnks2 |
G |
A |
19: 36,856,839 (GRCm39) |
V855I |
probably benign |
Het |
| Trank1 |
T |
C |
9: 111,196,194 (GRCm39) |
L1406S |
probably damaging |
Het |
| Trhde |
T |
C |
10: 114,636,478 (GRCm39) |
E243G |
probably damaging |
Het |
| Trim25 |
A |
T |
11: 88,906,608 (GRCm39) |
N448I |
probably benign |
Het |
| Trim31 |
T |
A |
17: 37,218,194 (GRCm39) |
M308K |
probably benign |
Het |
| Ugt2b36 |
A |
T |
5: 87,214,138 (GRCm39) |
V502E |
possibly damaging |
Het |
| Usp10 |
A |
C |
8: 120,668,344 (GRCm39) |
D215A |
possibly damaging |
Het |
| Usp33 |
T |
G |
3: 152,066,026 (GRCm39) |
L102* |
probably null |
Het |
| Wdr12 |
A |
T |
1: 60,121,734 (GRCm39) |
C272* |
probably null |
Het |
| Xndc1 |
A |
C |
7: 101,727,938 (GRCm39) |
|
probably null |
Het |
| Zkscan2 |
T |
C |
7: 123,089,276 (GRCm39) |
I332V |
possibly damaging |
Het |
| Zswim5 |
A |
T |
4: 116,841,885 (GRCm39) |
T822S |
probably benign |
Het |
|
| Other mutations in Itga10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01473:Itga10
|
APN |
3 |
96,554,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01694:Itga10
|
APN |
3 |
96,559,833 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01754:Itga10
|
APN |
3 |
96,564,091 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02527:Itga10
|
APN |
3 |
96,562,940 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02956:Itga10
|
APN |
3 |
96,562,429 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL03371:Itga10
|
APN |
3 |
96,562,104 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL03055:Itga10
|
UTSW |
3 |
96,557,836 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4515001:Itga10
|
UTSW |
3 |
96,569,948 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0153:Itga10
|
UTSW |
3 |
96,561,016 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0308:Itga10
|
UTSW |
3 |
96,558,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0331:Itga10
|
UTSW |
3 |
96,559,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0413:Itga10
|
UTSW |
3 |
96,556,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0437:Itga10
|
UTSW |
3 |
96,556,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0511:Itga10
|
UTSW |
3 |
96,565,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Itga10
|
UTSW |
3 |
96,563,615 (GRCm39) |
unclassified |
probably benign |
|
|
R0844:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R0849:Itga10
|
UTSW |
3 |
96,559,846 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0894:Itga10
|
UTSW |
3 |
96,560,976 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0919:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R1027:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R1341:Itga10
|
UTSW |
3 |
96,559,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1350:Itga10
|
UTSW |
3 |
96,564,793 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1370:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R1467:Itga10
|
UTSW |
3 |
96,559,545 (GRCm39) |
nonsense |
probably null |
|
|
R1467:Itga10
|
UTSW |
3 |
96,559,545 (GRCm39) |
nonsense |
probably null |
|
|
R1589:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R1590:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R1601:Itga10
|
UTSW |
3 |
96,560,974 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1659:Itga10
|
UTSW |
3 |
96,570,293 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1665:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R1667:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R1686:Itga10
|
UTSW |
3 |
96,559,141 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1972:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R1976:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R2020:Itga10
|
UTSW |
3 |
96,559,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2040:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R2044:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R2044:Itga10
|
UTSW |
3 |
96,565,006 (GRCm39) |
missense |
probably benign |
|
|
R2045:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R2060:Itga10
|
UTSW |
3 |
96,562,314 (GRCm39) |
nonsense |
probably null |
|
|
R2146:Itga10
|
UTSW |
3 |
96,561,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2146:Itga10
|
UTSW |
3 |
96,558,808 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R2170:Itga10
|
UTSW |
3 |
96,557,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2893:Itga10
|
UTSW |
3 |
96,562,416 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2926:Itga10
|
UTSW |
3 |
96,560,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3622:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R3623:Itga10
|
UTSW |
3 |
96,559,054 (GRCm39) |
splice site |
probably benign |
|
|
R4416:Itga10
|
UTSW |
3 |
96,565,562 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R4633:Itga10
|
UTSW |
3 |
96,555,020 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5074:Itga10
|
UTSW |
3 |
96,559,527 (GRCm39) |
nonsense |
probably null |
|
|
R5095:Itga10
|
UTSW |
3 |
96,555,480 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5495:Itga10
|
UTSW |
3 |
96,554,687 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5813:Itga10
|
UTSW |
3 |
96,559,901 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6114:Itga10
|
UTSW |
3 |
96,556,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6172:Itga10
|
UTSW |
3 |
96,554,753 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6275:Itga10
|
UTSW |
3 |
96,565,501 (GRCm39) |
missense |
probably benign |
0.36 |
|
R6298:Itga10
|
UTSW |
3 |
96,564,078 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6433:Itga10
|
UTSW |
3 |
96,565,357 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6841:Itga10
|
UTSW |
3 |
96,564,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6909:Itga10
|
UTSW |
3 |
96,569,915 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6927:Itga10
|
UTSW |
3 |
96,564,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7124:Itga10
|
UTSW |
3 |
96,559,081 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7387:Itga10
|
UTSW |
3 |
96,560,094 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7464:Itga10
|
UTSW |
3 |
96,555,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7624:Itga10
|
UTSW |
3 |
96,560,269 (GRCm39) |
missense |
probably benign |
|
|
R7638:Itga10
|
UTSW |
3 |
96,564,707 (GRCm39) |
splice site |
probably null |
|
|
R7639:Itga10
|
UTSW |
3 |
96,556,898 (GRCm39) |
missense |
probably benign |
0.36 |
|
R7893:Itga10
|
UTSW |
3 |
96,556,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8297:Itga10
|
UTSW |
3 |
96,562,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8753:Itga10
|
UTSW |
3 |
96,558,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9526:Itga10
|
UTSW |
3 |
96,564,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0064:Itga10
|
UTSW |
3 |
96,560,252 (GRCm39) |
missense |
probably benign |
0.03 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCGTGGTAAGGGAAATTAGTC -3'
(R):5'- ACAGGAGCCTCTTCTGCAAG -3'
Sequencing Primer
(F):5'- TTCAAAACCCTAGAGAGCAAGG -3'
(R):5'- GAGCCTCTTCTGCAAGCACAC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation