Incidental Mutation 'R7324:Dennd4c'
| ID |
568735 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4c
|
| Ensembl Gene |
ENSMUSG00000038024 |
| Gene Name |
DENN domain containing 4C |
| Synonyms |
1700065A05Rik |
| MMRRC Submission |
045418-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7324 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
86666792-86768840 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 86747975 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 1615
(L1615P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039860
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045512]
[ENSMUST00000082026]
[ENSMUST00000142837]
|
| AlphaFold |
A6H8H2 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000045512
AA Change: L1615P
|
| SMART Domains |
Protein: ENSMUSP00000039860
Gene: ENSMUSG00000038024
AA Change: L1615P
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
43 |
91 |
2.15e-5 |
PROSPERO |
|
uDENN
|
168 |
275 |
3.96e-24 |
SMART |
|
DENN
|
307 |
491 |
7.16e-72 |
SMART |
|
dDENN
|
557 |
631 |
1.85e-24 |
SMART |
|
low complexity region
|
983 |
1001 |
N/A |
INTRINSIC |
|
low complexity region
|
1013 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1052 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1377 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1472 |
1486 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000082026
|
| SMART Domains |
Protein: ENSMUSP00000080685
Gene: ENSMUSG00000038024
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
43 |
91 |
3.19e-5 |
PROSPERO |
|
uDENN
|
168 |
275 |
3.96e-24 |
SMART |
|
DENN
|
307 |
491 |
7.16e-72 |
SMART |
|
dDENN
|
557 |
631 |
1.85e-24 |
SMART |
|
low complexity region
|
983 |
1001 |
N/A |
INTRINSIC |
|
low complexity region
|
1013 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1052 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1377 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1472 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1724 |
1739 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000142837
|
| SMART Domains |
Protein: ENSMUSP00000123367
Gene: ENSMUSG00000038024
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
43 |
91 |
2.68e-5 |
PROSPERO |
|
uDENN
|
168 |
275 |
3.96e-24 |
SMART |
|
DENN
|
307 |
491 |
7.16e-72 |
SMART |
|
dDENN
|
557 |
631 |
1.85e-24 |
SMART |
|
low complexity region
|
934 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
964 |
976 |
N/A |
INTRINSIC |
|
low complexity region
|
996 |
1003 |
N/A |
INTRINSIC |
|
low complexity region
|
1053 |
1064 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1343 |
N/A |
INTRINSIC |
|
low complexity region
|
1423 |
1437 |
N/A |
INTRINSIC |
|
low complexity region
|
1675 |
1690 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (81/82) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg5 |
T |
C |
17: 84,983,667 (GRCm39) |
D124G |
possibly damaging |
Het |
| Ackr3 |
C |
G |
1: 90,141,923 (GRCm39) |
N127K |
probably damaging |
Het |
| AL732309.1 |
A |
C |
2: 25,136,151 (GRCm39) |
M21R |
possibly damaging |
Het |
| Ankrd52 |
C |
A |
10: 128,222,032 (GRCm39) |
T552K |
possibly damaging |
Het |
| Arhgap28 |
T |
C |
17: 68,202,879 (GRCm39) |
|
probably null |
Het |
| Arid5b |
A |
T |
10: 67,964,752 (GRCm39) |
N306K |
probably benign |
Het |
| C1qtnf3 |
A |
C |
15: 10,952,707 (GRCm39) |
K56N |
probably benign |
Het |
| C2 |
C |
T |
17: 35,100,664 (GRCm39) |
G52D |
probably benign |
Het |
| Casz1 |
C |
T |
4: 149,031,490 (GRCm39) |
T1247M |
probably damaging |
Het |
| Cc2d2b |
A |
G |
19: 40,797,552 (GRCm39) |
D778G |
unknown |
Het |
| Cdh5 |
A |
G |
8: 104,869,425 (GRCm39) |
D717G |
probably damaging |
Het |
| Clca3a2 |
G |
A |
3: 144,514,372 (GRCm39) |
A445V |
probably damaging |
Het |
| Clca3b |
T |
A |
3: 144,547,181 (GRCm39) |
M319L |
possibly damaging |
Het |
| Csmd1 |
G |
A |
8: 16,108,721 (GRCm39) |
S1894L |
probably damaging |
Het |
| Csnk1g3 |
A |
G |
18: 54,052,090 (GRCm39) |
T220A |
probably damaging |
Het |
| Cyp2d10 |
T |
G |
15: 82,287,961 (GRCm39) |
T381P |
probably damaging |
Het |
| Ddb2 |
G |
A |
2: 91,067,229 (GRCm39) |
|
probably benign |
Het |
| Ddx24 |
C |
A |
12: 103,382,518 (GRCm39) |
L688F |
probably damaging |
Het |
| Dnah8 |
T |
A |
17: 31,003,099 (GRCm39) |
D3599E |
probably benign |
Het |
| Dst |
T |
C |
1: 34,045,305 (GRCm39) |
S13P |
possibly damaging |
Het |
| Efcab12 |
T |
C |
6: 115,800,555 (GRCm39) |
D156G |
probably benign |
Het |
| Enpp2 |
A |
G |
15: 54,741,170 (GRCm39) |
|
probably null |
Het |
| Ephx2 |
A |
G |
14: 66,322,803 (GRCm39) |
V490A |
probably damaging |
Het |
| Etnppl |
A |
G |
3: 130,423,224 (GRCm39) |
N308D |
probably damaging |
Het |
| F5 |
TCAGAAGACCTCCTCCCCAGACCTGGGCCAGGTGCCCCTTTCTCCAGATGACAACCAGAAGACCTCCTCCCCAGACCTGGGTCAGGTGTCCCTTTCTCCAGATGATAACCAGAAGACCTCCTCCCCAGACCTGGGTCAGGTGCCCCTTTCTCTAGATGACAACCAGAAGACGACCTCCCCAGACCTGGGTCAGGTGCCCCTTTCTCCAGATGACAACCAGA |
TCAGAAGACCTCCTCCCCAGACCTGGGTCAGGTGTCCCTTTCTCCAGATGATAACCAGAAGACCTCCTCCCCAGACCTGGGTCAGGTGCCCCTTTCTCTAGATGACAACCAGAAGACGACCTCCCCAGACCTGGGTCAGGTGCCCCTTTCTCCAGATGACAACCAGA |
1: 164,021,150 (GRCm39) |
|
probably benign |
Het |
| Fam162b |
A |
T |
10: 51,466,282 (GRCm39) |
|
probably null |
Het |
| Fancl |
A |
G |
11: 26,353,362 (GRCm39) |
E86G |
probably damaging |
Het |
| Flii |
G |
A |
11: 60,609,866 (GRCm39) |
T615I |
probably benign |
Het |
| Fndc7 |
G |
T |
3: 108,779,537 (GRCm39) |
Q336K |
probably benign |
Het |
| Gm26661 |
T |
C |
14: 7,791,911 (GRCm38) |
C109R |
unknown |
Het |
| H2-DMb1 |
T |
C |
17: 34,378,436 (GRCm39) |
|
probably null |
Het |
| H2-T10 |
C |
T |
17: 36,430,189 (GRCm39) |
G251R |
probably damaging |
Het |
| Harbi1 |
T |
C |
2: 91,551,044 (GRCm39) |
I339T |
probably benign |
Het |
| Hsp90aa1 |
A |
G |
12: 110,661,659 (GRCm39) |
M119T |
unknown |
Het |
| Ighe |
T |
A |
12: 113,235,954 (GRCm39) |
Y124F |
|
Het |
| Ighv7-1 |
T |
C |
12: 113,860,149 (GRCm39) |
Y81C |
probably damaging |
Het |
| Ilkap |
A |
T |
1: 91,313,115 (GRCm39) |
|
probably null |
Het |
| Inpp5a |
A |
G |
7: 139,105,586 (GRCm39) |
D179G |
probably damaging |
Het |
| Itgad |
A |
T |
7: 127,788,979 (GRCm39) |
D510V |
probably damaging |
Het |
| Kcnn2 |
A |
T |
18: 45,693,138 (GRCm39) |
H238L |
probably benign |
Het |
| Kctd17 |
T |
A |
15: 78,319,842 (GRCm39) |
C189S |
probably damaging |
Het |
| Larp4b |
C |
A |
13: 9,208,616 (GRCm39) |
A423E |
probably benign |
Het |
| Llgl2 |
A |
G |
11: 115,741,556 (GRCm39) |
E562G |
possibly damaging |
Het |
| Macf1 |
T |
C |
4: 123,268,218 (GRCm39) |
T6734A |
probably benign |
Het |
| Maz |
G |
A |
7: 126,623,765 (GRCm39) |
T377M |
probably damaging |
Het |
| Mmrn1 |
G |
T |
6: 60,921,917 (GRCm39) |
G125* |
probably null |
Het |
| Mvp |
A |
G |
7: 126,592,781 (GRCm39) |
S377P |
probably benign |
Het |
| Nin |
C |
T |
12: 70,090,508 (GRCm39) |
R969Q |
|
Het |
| Nktr |
C |
T |
9: 121,556,427 (GRCm39) |
T35I |
probably damaging |
Het |
| Nktr |
T |
A |
9: 121,577,357 (GRCm39) |
M475K |
possibly damaging |
Het |
| Nod2 |
T |
A |
8: 89,379,694 (GRCm39) |
V65D |
probably damaging |
Het |
| Opa1 |
A |
T |
16: 29,405,799 (GRCm39) |
E121D |
probably benign |
Het |
| Or10w3 |
C |
T |
19: 13,704,270 (GRCm39) |
A215V |
probably benign |
Het |
| Or1r1 |
A |
G |
11: 73,874,669 (GRCm39) |
V255A |
probably benign |
Het |
| Or2n1c |
T |
C |
17: 38,519,607 (GRCm39) |
V157A |
probably benign |
Het |
| Or4a76 |
A |
T |
2: 89,460,447 (GRCm39) |
I265N |
possibly damaging |
Het |
| Or5ac21 |
T |
C |
16: 59,123,611 (GRCm39) |
F32L |
probably benign |
Het |
| Or5b123 |
A |
G |
19: 13,596,942 (GRCm39) |
I96V |
probably benign |
Het |
| Or6c88 |
T |
A |
10: 129,406,718 (GRCm39) |
S65T |
probably damaging |
Het |
| Or7e174 |
A |
T |
9: 20,012,726 (GRCm39) |
I224F |
possibly damaging |
Het |
| Osbpl2 |
A |
G |
2: 179,791,994 (GRCm39) |
T233A |
probably benign |
Het |
| Pcp4l1 |
G |
A |
1: 171,002,034 (GRCm39) |
A42V |
possibly damaging |
Het |
| Plekhh3 |
T |
A |
11: 101,061,600 (GRCm39) |
D38V |
possibly damaging |
Het |
| Prtg |
C |
T |
9: 72,798,122 (GRCm39) |
A696V |
probably damaging |
Het |
| Ptpn14 |
T |
G |
1: 189,595,621 (GRCm39) |
V748G |
possibly damaging |
Het |
| Reg2 |
A |
T |
6: 78,383,137 (GRCm39) |
D28V |
probably benign |
Het |
| Rhpn1 |
A |
T |
15: 75,576,246 (GRCm39) |
I2F |
possibly damaging |
Het |
| Rundc3a |
A |
G |
11: 102,290,799 (GRCm39) |
E294G |
possibly damaging |
Het |
| Scara3 |
T |
A |
14: 66,168,865 (GRCm39) |
I251L |
probably benign |
Het |
| Slc23a2 |
G |
A |
2: 131,931,043 (GRCm39) |
T152I |
probably damaging |
Het |
| Slc39a2 |
T |
G |
14: 52,131,650 (GRCm39) |
S74A |
possibly damaging |
Het |
| Tmprss15 |
T |
C |
16: 78,758,907 (GRCm39) |
Y937C |
probably damaging |
Het |
| Tpp2 |
T |
C |
1: 44,017,938 (GRCm39) |
L779S |
probably damaging |
Het |
| Tssk2 |
T |
C |
16: 17,717,227 (GRCm39) |
V210A |
possibly damaging |
Het |
| Ttn |
T |
A |
2: 76,725,937 (GRCm39) |
T6100S |
unknown |
Het |
| Tufm |
G |
A |
7: 126,088,759 (GRCm39) |
E317K |
possibly damaging |
Het |
| Vinac1 |
T |
C |
2: 128,879,772 (GRCm39) |
D718G |
unknown |
Het |
| Wdfy4 |
A |
G |
14: 32,769,271 (GRCm39) |
S2219P |
|
Het |
| Wtap |
T |
C |
17: 13,199,833 (GRCm39) |
N50S |
possibly damaging |
Het |
|
| Other mutations in Dennd4c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01309:Dennd4c
|
APN |
4 |
86,723,724 (GRCm39) |
splice site |
probably benign |
|
|
IGL01810:Dennd4c
|
APN |
4 |
86,717,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02203:Dennd4c
|
APN |
4 |
86,721,173 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02217:Dennd4c
|
APN |
4 |
86,732,036 (GRCm39) |
missense |
probably benign |
|
|
IGL02236:Dennd4c
|
APN |
4 |
86,725,672 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02256:Dennd4c
|
APN |
4 |
86,717,778 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02396:Dennd4c
|
APN |
4 |
86,743,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02523:Dennd4c
|
APN |
4 |
86,692,490 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02615:Dennd4c
|
APN |
4 |
86,739,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03069:Dennd4c
|
APN |
4 |
86,692,674 (GRCm39) |
nonsense |
probably null |
|
|
IGL03116:Dennd4c
|
APN |
4 |
86,707,057 (GRCm39) |
splice site |
probably benign |
|
|
IGL03117:Dennd4c
|
APN |
4 |
86,696,140 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03273:Dennd4c
|
APN |
4 |
86,696,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03329:Dennd4c
|
APN |
4 |
86,696,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03365:Dennd4c
|
APN |
4 |
86,725,663 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
PIT4486001:Dennd4c
|
UTSW |
4 |
86,717,701 (GRCm39) |
nonsense |
probably null |
|
|
R0010:Dennd4c
|
UTSW |
4 |
86,699,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0032:Dennd4c
|
UTSW |
4 |
86,746,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0032:Dennd4c
|
UTSW |
4 |
86,746,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0092:Dennd4c
|
UTSW |
4 |
86,699,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0103:Dennd4c
|
UTSW |
4 |
86,730,683 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0103:Dennd4c
|
UTSW |
4 |
86,730,683 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0511:Dennd4c
|
UTSW |
4 |
86,744,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0515:Dennd4c
|
UTSW |
4 |
86,731,703 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0578:Dennd4c
|
UTSW |
4 |
86,730,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0759:Dennd4c
|
UTSW |
4 |
86,707,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0784:Dennd4c
|
UTSW |
4 |
86,763,145 (GRCm39) |
missense |
probably benign |
0.37 |
|
R1156:Dennd4c
|
UTSW |
4 |
86,725,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1370:Dennd4c
|
UTSW |
4 |
86,729,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1381:Dennd4c
|
UTSW |
4 |
86,692,769 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1569:Dennd4c
|
UTSW |
4 |
86,704,331 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R1747:Dennd4c
|
UTSW |
4 |
86,725,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1764:Dennd4c
|
UTSW |
4 |
86,721,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Dennd4c
|
UTSW |
4 |
86,743,415 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1997:Dennd4c
|
UTSW |
4 |
86,755,634 (GRCm39) |
missense |
probably benign |
|
|
R2244:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2348:Dennd4c
|
UTSW |
4 |
86,729,764 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2968:Dennd4c
|
UTSW |
4 |
86,699,881 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3033:Dennd4c
|
UTSW |
4 |
86,743,557 (GRCm39) |
small deletion |
probably benign |
|
|
R3401:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3402:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3403:Dennd4c
|
UTSW |
4 |
86,692,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3855:Dennd4c
|
UTSW |
4 |
86,698,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3939:Dennd4c
|
UTSW |
4 |
86,692,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4164:Dennd4c
|
UTSW |
4 |
86,725,764 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4384:Dennd4c
|
UTSW |
4 |
86,729,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4435:Dennd4c
|
UTSW |
4 |
86,716,312 (GRCm39) |
missense |
probably benign |
0.44 |
|
R4788:Dennd4c
|
UTSW |
4 |
86,738,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4801:Dennd4c
|
UTSW |
4 |
86,738,121 (GRCm39) |
nonsense |
probably null |
|
|
R4802:Dennd4c
|
UTSW |
4 |
86,738,121 (GRCm39) |
nonsense |
probably null |
|
|
R4818:Dennd4c
|
UTSW |
4 |
86,743,511 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4923:Dennd4c
|
UTSW |
4 |
86,725,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4958:Dennd4c
|
UTSW |
4 |
86,699,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5025:Dennd4c
|
UTSW |
4 |
86,713,536 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5434:Dennd4c
|
UTSW |
4 |
86,729,693 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5662:Dennd4c
|
UTSW |
4 |
86,713,525 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5802:Dennd4c
|
UTSW |
4 |
86,729,690 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5849:Dennd4c
|
UTSW |
4 |
86,744,223 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5861:Dennd4c
|
UTSW |
4 |
86,709,589 (GRCm39) |
missense |
probably benign |
0.30 |
|
R5970:Dennd4c
|
UTSW |
4 |
86,743,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6163:Dennd4c
|
UTSW |
4 |
86,723,828 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6356:Dennd4c
|
UTSW |
4 |
86,743,686 (GRCm39) |
missense |
probably benign |
|
|
R6661:Dennd4c
|
UTSW |
4 |
86,717,626 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6855:Dennd4c
|
UTSW |
4 |
86,754,694 (GRCm39) |
missense |
probably benign |
|
|
R6983:Dennd4c
|
UTSW |
4 |
86,717,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7035:Dennd4c
|
UTSW |
4 |
86,730,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7126:Dennd4c
|
UTSW |
4 |
86,725,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7185:Dennd4c
|
UTSW |
4 |
86,729,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7212:Dennd4c
|
UTSW |
4 |
86,721,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7329:Dennd4c
|
UTSW |
4 |
86,698,111 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7329:Dennd4c
|
UTSW |
4 |
86,759,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7466:Dennd4c
|
UTSW |
4 |
86,692,568 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7479:Dennd4c
|
UTSW |
4 |
86,717,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7538:Dennd4c
|
UTSW |
4 |
86,692,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7599:Dennd4c
|
UTSW |
4 |
86,729,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7688:Dennd4c
|
UTSW |
4 |
86,713,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7725:Dennd4c
|
UTSW |
4 |
86,704,330 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7751:Dennd4c
|
UTSW |
4 |
86,747,179 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7790:Dennd4c
|
UTSW |
4 |
86,717,754 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8056:Dennd4c
|
UTSW |
4 |
86,763,213 (GRCm39) |
missense |
probably null |
0.71 |
|
R8307:Dennd4c
|
UTSW |
4 |
86,744,109 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8494:Dennd4c
|
UTSW |
4 |
86,759,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8531:Dennd4c
|
UTSW |
4 |
86,744,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9014:Dennd4c
|
UTSW |
4 |
86,754,666 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9014:Dennd4c
|
UTSW |
4 |
86,739,702 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9017:Dennd4c
|
UTSW |
4 |
86,743,349 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9142:Dennd4c
|
UTSW |
4 |
86,755,637 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9224:Dennd4c
|
UTSW |
4 |
86,738,170 (GRCm39) |
nonsense |
probably null |
|
|
R9570:Dennd4c
|
UTSW |
4 |
86,747,208 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9644:Dennd4c
|
UTSW |
4 |
86,713,363 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9649:Dennd4c
|
UTSW |
4 |
86,743,160 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9658:Dennd4c
|
UTSW |
4 |
86,754,625 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTCACAGTGCAGAGCTTGTG -3'
(R):5'- TGGTGCTCAGGATCCAAACG -3'
Sequencing Primer
(F):5'- CGCTCTGGTTTATGATGAGGAAATC -3'
(R):5'- GGATCCAAACGCAGGCTCAG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation