Incidental Mutation 'R7326:Nwd2'
| ID |
568887 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nwd2
|
| Ensembl Gene |
ENSMUSG00000090061 |
| Gene Name |
NACHT and WD repeat domain containing 2 |
| Synonyms |
3110047P20Rik, B830017A01Rik |
| MMRRC Submission |
045378-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.120)
|
| Stock # |
R7326 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
63806446-63967889 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 63957752 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Tyrosine
at position 361
(N361Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124712
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159584]
[ENSMUST00000162166]
|
| AlphaFold |
Q6P5U7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000159584
AA Change: N361Y
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000124712
Gene: ENSMUSG00000090061
AA Change: N361Y
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4062
|
42 |
145 |
1.5e-8 |
PFAM |
|
Blast:AAA
|
408 |
691 |
3e-29 |
BLAST |
|
WD40
|
939 |
995 |
1.06e2 |
SMART |
|
WD40
|
998 |
1037 |
8.96e-2 |
SMART |
|
Blast:WD40
|
1091 |
1126 |
9e-19 |
BLAST |
|
Blast:WD40
|
1129 |
1170 |
1e-17 |
BLAST |
|
Blast:WD40
|
1220 |
1260 |
3e-16 |
BLAST |
|
WD40
|
1263 |
1302 |
3.4e-2 |
SMART |
|
WD40
|
1347 |
1385 |
2.65e1 |
SMART |
|
WD40
|
1386 |
1425 |
1.58e2 |
SMART |
|
Blast:WD40
|
1466 |
1507 |
3e-19 |
BLAST |
|
Blast:WD40
|
1606 |
1644 |
4e-18 |
BLAST |
|
Blast:KR
|
1686 |
1730 |
2e-16 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162166
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162757
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 112 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb4 |
T |
C |
5: 8,984,226 (GRCm39) |
V652A |
probably benign |
Het |
| Acvrl1 |
G |
T |
15: 101,038,953 (GRCm39) |
V417L |
probably damaging |
Het |
| Add1 |
A |
G |
5: 34,776,715 (GRCm39) |
R479G |
probably benign |
Het |
| Adgb |
A |
T |
10: 10,276,318 (GRCm39) |
L350Q |
possibly damaging |
Het |
| Adgrl2 |
A |
T |
3: 148,552,506 (GRCm39) |
S666T |
probably benign |
Het |
| Akap9 |
T |
A |
5: 4,095,930 (GRCm39) |
D2268E |
possibly damaging |
Het |
| Amigo3 |
C |
A |
9: 107,931,265 (GRCm39) |
H229Q |
probably benign |
Het |
| Ano6 |
G |
C |
15: 95,762,125 (GRCm39) |
Q31H |
possibly damaging |
Het |
| Ap4m1 |
G |
A |
5: 138,173,281 (GRCm39) |
D180N |
probably damaging |
Het |
| Apc2 |
A |
T |
10: 80,147,574 (GRCm39) |
D876V |
probably damaging |
Het |
| Apcdd1 |
T |
A |
18: 63,085,259 (GRCm39) |
Y485* |
probably null |
Het |
| Aqp1 |
G |
T |
6: 55,313,836 (GRCm39) |
D121Y |
probably benign |
Het |
| Bicd2 |
C |
A |
13: 49,523,085 (GRCm39) |
R141S |
probably benign |
Het |
| Brpf3 |
C |
A |
17: 29,025,267 (GRCm39) |
H113Q |
probably benign |
Het |
| Cacng2 |
A |
T |
15: 77,897,520 (GRCm39) |
Y96* |
probably null |
Het |
| Catsperg1 |
G |
T |
7: 28,910,184 (GRCm39) |
N52K |
possibly damaging |
Het |
| Celsr2 |
A |
C |
3: 108,302,311 (GRCm39) |
F2606V |
possibly damaging |
Het |
| Cerkl |
A |
T |
2: 79,162,949 (GRCm39) |
N516K |
probably benign |
Het |
| Ciita |
G |
A |
16: 10,330,152 (GRCm39) |
R812H |
probably damaging |
Het |
| Cldn3 |
T |
A |
5: 135,015,837 (GRCm39) |
L180Q |
probably damaging |
Het |
| Cnot6l |
T |
C |
5: 96,225,158 (GRCm39) |
I512V |
probably benign |
Het |
| Col5a2 |
A |
T |
1: 45,482,027 (GRCm39) |
D32E |
unknown |
Het |
| Coro7 |
A |
G |
16: 4,449,912 (GRCm39) |
V616A |
probably damaging |
Het |
| Cyp4f18 |
T |
C |
8: 72,742,498 (GRCm39) |
D494G |
probably benign |
Het |
| Ddx39a |
T |
A |
8: 84,449,100 (GRCm39) |
V296E |
probably benign |
Het |
| Dgkg |
A |
T |
16: 22,367,440 (GRCm39) |
H593Q |
probably damaging |
Het |
| Dhx16 |
T |
C |
17: 36,197,052 (GRCm39) |
L645P |
probably damaging |
Het |
| Dnah14 |
A |
G |
1: 181,425,968 (GRCm39) |
M171V |
probably benign |
Het |
| Dnhd1 |
G |
A |
7: 105,370,137 (GRCm39) |
V4521I |
probably damaging |
Het |
| Dok7 |
A |
T |
5: 35,221,866 (GRCm39) |
M60L |
probably benign |
Het |
| Donson |
A |
T |
16: 91,485,599 (GRCm39) |
M1K |
probably null |
Het |
| Dsp |
C |
T |
13: 38,376,859 (GRCm39) |
T1548M |
probably benign |
Het |
| Dyrk1a |
A |
G |
16: 94,492,902 (GRCm39) |
T712A |
probably damaging |
Het |
| Eef2 |
A |
G |
10: 81,017,116 (GRCm39) |
T708A |
probably benign |
Het |
| Epn3 |
G |
A |
11: 94,384,606 (GRCm39) |
T289I |
probably benign |
Het |
| Fam171a1 |
C |
T |
2: 3,227,509 (GRCm39) |
R881* |
probably null |
Het |
| Fat2 |
T |
A |
11: 55,173,130 (GRCm39) |
R2528W |
probably damaging |
Het |
| Fbxl9 |
T |
C |
8: 106,039,530 (GRCm39) |
D127G |
probably damaging |
Het |
| Fgfr1 |
T |
G |
8: 26,063,855 (GRCm39) |
F707C |
probably damaging |
Het |
| Frem2 |
G |
C |
3: 53,562,174 (GRCm39) |
P778A |
probably damaging |
Het |
| Ganc |
A |
G |
2: 120,261,080 (GRCm39) |
Y255C |
probably damaging |
Het |
| Garin4 |
G |
A |
1: 190,896,550 (GRCm39) |
T31M |
probably benign |
Het |
| Ginm1 |
A |
T |
10: 7,653,614 (GRCm39) |
Y65* |
probably null |
Het |
| Gm11559 |
T |
A |
11: 99,755,707 (GRCm39) |
C119S |
unknown |
Het |
| Gnai1 |
T |
A |
5: 18,494,549 (GRCm39) |
H188L |
|
Het |
| H2bc6 |
T |
C |
13: 23,769,906 (GRCm39) |
K12E |
probably benign |
Het |
| H6pd |
C |
T |
4: 150,080,807 (GRCm39) |
A13T |
probably benign |
Het |
| Hoxd12 |
A |
T |
2: 74,505,590 (GRCm39) |
T54S |
possibly damaging |
Het |
| Hs3st5 |
T |
A |
10: 36,709,190 (GRCm39) |
L242M |
probably damaging |
Het |
| Il9r |
C |
A |
11: 32,144,389 (GRCm39) |
V139L |
possibly damaging |
Het |
| Immt |
A |
G |
6: 71,823,353 (GRCm39) |
D68G |
probably damaging |
Het |
| Itsn2 |
A |
G |
12: 4,682,985 (GRCm39) |
I304V |
unknown |
Het |
| Lgr4 |
G |
A |
2: 109,826,974 (GRCm39) |
W159* |
probably null |
Het |
| Lin52 |
G |
A |
12: 84,504,728 (GRCm39) |
G38S |
probably damaging |
Het |
| Lpgat1 |
A |
T |
1: 191,451,565 (GRCm39) |
M64L |
probably benign |
Het |
| Lrrc10b |
G |
T |
19: 10,434,142 (GRCm39) |
R180S |
possibly damaging |
Het |
| Lrrc36 |
A |
T |
8: 106,176,401 (GRCm39) |
L258F |
possibly damaging |
Het |
| Ltbp4 |
T |
A |
7: 27,029,180 (GRCm39) |
Q235L |
unknown |
Het |
| Maml2 |
A |
G |
9: 13,532,903 (GRCm39) |
M706V |
|
Het |
| Mc5r |
G |
T |
18: 68,472,739 (GRCm39) |
C366F |
probably damaging |
Het |
| Mlip |
T |
C |
9: 77,072,124 (GRCm39) |
R244G |
probably benign |
Het |
| Muc16 |
T |
A |
9: 18,496,309 (GRCm39) |
R6658S |
probably benign |
Het |
| Mup4 |
G |
T |
4: 59,960,046 (GRCm39) |
H73N |
possibly damaging |
Het |
| Nf1 |
A |
G |
11: 79,455,769 (GRCm39) |
M565V |
probably benign |
Het |
| Nphp1 |
G |
A |
2: 127,603,137 (GRCm39) |
T382I |
possibly damaging |
Het |
| Nrcam |
C |
T |
12: 44,610,809 (GRCm39) |
T503I |
possibly damaging |
Het |
| Or10a3 |
A |
T |
7: 108,480,023 (GRCm39) |
H263Q |
probably damaging |
Het |
| Or4f15 |
A |
T |
2: 111,813,672 (GRCm39) |
L249* |
probably null |
Het |
| Or5ak23 |
A |
T |
2: 85,244,788 (GRCm39) |
V145E |
probably damaging |
Het |
| Or6f1 |
A |
G |
7: 85,970,782 (GRCm39) |
I126T |
probably damaging |
Het |
| Or7g21 |
A |
G |
9: 19,032,965 (GRCm39) |
Y235C |
probably benign |
Het |
| Or8j3 |
A |
G |
2: 86,028,917 (GRCm39) |
Y60H |
probably damaging |
Het |
| Or9a7 |
G |
T |
6: 40,521,829 (GRCm39) |
A28E |
probably damaging |
Het |
| Orc5 |
A |
G |
5: 22,728,582 (GRCm39) |
F308L |
probably benign |
Het |
| Padi1 |
T |
A |
4: 140,559,715 (GRCm39) |
Y54F |
probably benign |
Het |
| Parp1 |
A |
G |
1: 180,396,665 (GRCm39) |
K23E |
possibly damaging |
Het |
| Pate1 |
A |
T |
9: 35,597,268 (GRCm39) |
V79D |
possibly damaging |
Het |
| Pcdh18 |
T |
C |
3: 49,711,309 (GRCm39) |
H2R |
probably benign |
Het |
| Pcnx2 |
G |
A |
8: 126,613,822 (GRCm39) |
S543F |
probably damaging |
Het |
| Pcp4l1 |
G |
A |
1: 171,002,034 (GRCm39) |
A42V |
possibly damaging |
Het |
| Pnkp |
T |
A |
7: 44,509,158 (GRCm39) |
F169L |
probably damaging |
Het |
| Ppp6r3 |
A |
T |
19: 3,557,325 (GRCm39) |
N254K |
probably damaging |
Het |
| Psd |
A |
G |
19: 46,312,893 (GRCm39) |
L159P |
probably benign |
Het |
| Ptprf |
A |
G |
4: 118,088,866 (GRCm39) |
Y646H |
probably damaging |
Het |
| Rab3ip |
A |
T |
10: 116,773,538 (GRCm39) |
S92T |
probably benign |
Het |
| Rabgef1 |
A |
G |
5: 130,216,192 (GRCm39) |
|
probably benign |
Het |
| Ralgapa1 |
C |
A |
12: 55,755,789 (GRCm39) |
W1129L |
probably damaging |
Het |
| Rhpn2 |
T |
A |
7: 35,084,888 (GRCm39) |
L594Q |
probably benign |
Het |
| Rnf38 |
C |
A |
4: 44,158,989 (GRCm39) |
|
probably benign |
Het |
| Ryr2 |
T |
A |
13: 11,753,080 (GRCm39) |
H1747L |
possibly damaging |
Het |
| Sec16a |
A |
G |
2: 26,329,729 (GRCm39) |
L13P |
unknown |
Het |
| Spef1l |
A |
T |
7: 139,558,458 (GRCm39) |
|
probably null |
Het |
| Sppl3 |
C |
A |
5: 115,220,394 (GRCm39) |
T102K |
probably damaging |
Het |
| Srgap2 |
A |
T |
1: 131,219,351 (GRCm39) |
Y264* |
probably null |
Het |
| Stxbp2 |
T |
C |
8: 3,691,151 (GRCm39) |
M465T |
|
Het |
| Sumf2 |
A |
G |
5: 129,891,551 (GRCm39) |
K305R |
probably benign |
Het |
| Susd2 |
T |
A |
10: 75,478,399 (GRCm39) |
Y59F |
probably benign |
Het |
| Taco1 |
T |
C |
11: 105,963,443 (GRCm39) |
V198A |
probably benign |
Het |
| Tas2r136 |
A |
T |
6: 132,754,869 (GRCm39) |
M86K |
possibly damaging |
Het |
| Tbc1d10c |
T |
C |
19: 4,234,897 (GRCm39) |
E388G |
possibly damaging |
Het |
| Tmem132c |
C |
T |
5: 127,641,123 (GRCm39) |
T1098I |
possibly damaging |
Het |
| Trim3 |
G |
T |
7: 105,267,007 (GRCm39) |
Y457* |
probably null |
Het |
| Ttc38 |
A |
G |
15: 85,737,062 (GRCm39) |
T316A |
probably benign |
Het |
| Ubqln4 |
T |
A |
3: 88,463,217 (GRCm39) |
N127K |
probably benign |
Het |
| Wdr91 |
A |
T |
6: 34,881,561 (GRCm39) |
F262Y |
probably damaging |
Het |
| Zdhhc6 |
A |
T |
19: 55,291,187 (GRCm39) |
C343S |
possibly damaging |
Het |
| Zfp248 |
A |
G |
6: 118,407,170 (GRCm39) |
C140R |
probably damaging |
Het |
| Zfp266 |
T |
C |
9: 20,413,391 (GRCm39) |
T90A |
probably benign |
Het |
| Zfp407 |
A |
T |
18: 84,577,167 (GRCm39) |
D1315E |
possibly damaging |
Het |
| Zfp644 |
T |
C |
5: 106,786,143 (GRCm39) |
S135G |
probably benign |
Het |
| Zscan29 |
A |
T |
2: 120,991,469 (GRCm39) |
I773N |
probably damaging |
Het |
| Zswim5 |
T |
A |
4: 116,838,031 (GRCm39) |
V787E |
possibly damaging |
Het |
|
| Other mutations in Nwd2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Nwd2
|
APN |
5 |
63,962,818 (GRCm39) |
missense |
probably benign |
|
|
IGL01111:Nwd2
|
APN |
5 |
63,964,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01152:Nwd2
|
APN |
5 |
63,963,872 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01307:Nwd2
|
APN |
5 |
63,965,626 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01449:Nwd2
|
APN |
5 |
63,962,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01624:Nwd2
|
APN |
5 |
63,964,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01997:Nwd2
|
APN |
5 |
63,961,938 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02007:Nwd2
|
APN |
5 |
63,962,042 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02143:Nwd2
|
APN |
5 |
63,948,996 (GRCm39) |
splice site |
probably null |
|
|
IGL02184:Nwd2
|
APN |
5 |
63,963,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02379:Nwd2
|
APN |
5 |
63,962,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02489:Nwd2
|
APN |
5 |
63,962,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02580:Nwd2
|
APN |
5 |
63,965,512 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,020 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02891:Nwd2
|
APN |
5 |
63,882,570 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03135:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03149:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0113:Nwd2
|
UTSW |
5 |
63,965,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0172:Nwd2
|
UTSW |
5 |
63,963,712 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0196:Nwd2
|
UTSW |
5 |
63,963,694 (GRCm39) |
missense |
probably benign |
0.37 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0309:Nwd2
|
UTSW |
5 |
63,964,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0311:Nwd2
|
UTSW |
5 |
63,962,341 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0335:Nwd2
|
UTSW |
5 |
63,962,116 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0384:Nwd2
|
UTSW |
5 |
63,963,025 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0496:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0497:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0498:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0505:Nwd2
|
UTSW |
5 |
63,962,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0655:Nwd2
|
UTSW |
5 |
63,948,928 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0762:Nwd2
|
UTSW |
5 |
63,957,757 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0835:Nwd2
|
UTSW |
5 |
63,957,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0926:Nwd2
|
UTSW |
5 |
63,965,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0948:Nwd2
|
UTSW |
5 |
63,964,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1015:Nwd2
|
UTSW |
5 |
63,964,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1086:Nwd2
|
UTSW |
5 |
63,963,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1186:Nwd2
|
UTSW |
5 |
63,807,367 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1305:Nwd2
|
UTSW |
5 |
63,902,540 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1542:Nwd2
|
UTSW |
5 |
63,964,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1548:Nwd2
|
UTSW |
5 |
63,957,525 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Nwd2
|
UTSW |
5 |
63,957,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1636:Nwd2
|
UTSW |
5 |
63,964,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1658:Nwd2
|
UTSW |
5 |
63,964,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Nwd2
|
UTSW |
5 |
63,965,614 (GRCm39) |
missense |
probably benign |
|
|
R1800:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1813:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1861:Nwd2
|
UTSW |
5 |
63,962,197 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1889:Nwd2
|
UTSW |
5 |
63,965,009 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1896:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1919:Nwd2
|
UTSW |
5 |
63,963,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1922:Nwd2
|
UTSW |
5 |
63,951,585 (GRCm39) |
missense |
probably benign |
|
|
R2258:Nwd2
|
UTSW |
5 |
63,962,499 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2292:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R2504:Nwd2
|
UTSW |
5 |
63,961,717 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2958:Nwd2
|
UTSW |
5 |
63,963,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3034:Nwd2
|
UTSW |
5 |
63,957,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3422:Nwd2
|
UTSW |
5 |
63,882,536 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3423:Nwd2
|
UTSW |
5 |
63,957,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3439:Nwd2
|
UTSW |
5 |
63,961,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4193:Nwd2
|
UTSW |
5 |
63,964,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4254:Nwd2
|
UTSW |
5 |
63,963,889 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4384:Nwd2
|
UTSW |
5 |
63,963,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Nwd2
|
UTSW |
5 |
63,951,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4713:Nwd2
|
UTSW |
5 |
63,961,803 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4735:Nwd2
|
UTSW |
5 |
63,965,594 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4744:Nwd2
|
UTSW |
5 |
63,964,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Nwd2
|
UTSW |
5 |
63,962,776 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4835:Nwd2
|
UTSW |
5 |
63,965,189 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4839:Nwd2
|
UTSW |
5 |
63,962,893 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4896:Nwd2
|
UTSW |
5 |
63,962,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5017:Nwd2
|
UTSW |
5 |
63,807,484 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5170:Nwd2
|
UTSW |
5 |
63,963,380 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5312:Nwd2
|
UTSW |
5 |
63,963,415 (GRCm39) |
nonsense |
probably null |
|
|
R5330:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5331:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5419:Nwd2
|
UTSW |
5 |
63,965,051 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5434:Nwd2
|
UTSW |
5 |
63,964,991 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5445:Nwd2
|
UTSW |
5 |
63,962,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Nwd2
|
UTSW |
5 |
63,882,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5788:Nwd2
|
UTSW |
5 |
63,965,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5907:Nwd2
|
UTSW |
5 |
63,963,326 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5959:Nwd2
|
UTSW |
5 |
63,965,413 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6002:Nwd2
|
UTSW |
5 |
63,962,143 (GRCm39) |
missense |
probably benign |
|
|
R6027:Nwd2
|
UTSW |
5 |
63,965,563 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6082:Nwd2
|
UTSW |
5 |
63,962,374 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6163:Nwd2
|
UTSW |
5 |
63,963,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6172:Nwd2
|
UTSW |
5 |
63,964,249 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6334:Nwd2
|
UTSW |
5 |
63,957,596 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6447:Nwd2
|
UTSW |
5 |
63,964,898 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6649:Nwd2
|
UTSW |
5 |
63,882,527 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6855:Nwd2
|
UTSW |
5 |
63,961,794 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7034:Nwd2
|
UTSW |
5 |
63,962,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7168:Nwd2
|
UTSW |
5 |
63,964,837 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7561:Nwd2
|
UTSW |
5 |
63,964,434 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Nwd2
|
UTSW |
5 |
63,964,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7580:Nwd2
|
UTSW |
5 |
63,965,624 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7723:Nwd2
|
UTSW |
5 |
63,965,347 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7769:Nwd2
|
UTSW |
5 |
63,961,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8293:Nwd2
|
UTSW |
5 |
63,962,663 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8517:Nwd2
|
UTSW |
5 |
63,948,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8792:Nwd2
|
UTSW |
5 |
63,963,047 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8888:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8895:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8901:Nwd2
|
UTSW |
5 |
63,963,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Nwd2
|
UTSW |
5 |
63,963,440 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8920:Nwd2
|
UTSW |
5 |
63,948,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9052:Nwd2
|
UTSW |
5 |
63,961,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Nwd2
|
UTSW |
5 |
63,961,747 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9368:Nwd2
|
UTSW |
5 |
63,962,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9377:Nwd2
|
UTSW |
5 |
63,957,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9430:Nwd2
|
UTSW |
5 |
63,964,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Nwd2
|
UTSW |
5 |
63,964,568 (GRCm39) |
nonsense |
probably null |
|
|
R9661:Nwd2
|
UTSW |
5 |
63,957,780 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9736:Nwd2
|
UTSW |
5 |
63,951,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9793:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9795:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF020:Nwd2
|
UTSW |
5 |
63,963,066 (GRCm39) |
nonsense |
probably null |
|
|
X0023:Nwd2
|
UTSW |
5 |
63,964,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,963,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nwd2
|
UTSW |
5 |
63,964,669 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Nwd2
|
UTSW |
5 |
63,962,327 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCAGAAGCTCAAGAGAAGCTG -3'
(R):5'- CAGTAGAGTCTTCCCAGTGC -3'
Sequencing Primer
(F):5'- GCTGATAAAACTCAGGGATGAATTC -3'
(R):5'- CCAGTGCATGGTCCCCC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation