Mutagenetix > Incidental Mutation

Incidental Mutation 'R7336:Tenm3'

569499

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Odz3, Ten-m3, 2610100B16Rik

MMRRC Submission

045426-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.584) question?

Stock #

R7336 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

48680717-49296986 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 48689212 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Lysine at position 2125 (M2125K)

Ref Sequence

ENSEMBL: ENSMUSP00000033965 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000033965
AA Change: M2125K

PolyPhen 2 Score 0.933 (Sensitivity: 0.80; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: M2125K

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000190840
AA Change: M2109K

PolyPhen 2 Score 0.663 (Sensitivity: 0.86; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: M2109K

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 98.9%

Validation Efficiency

99% (80/81)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 79 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl2fm1	G	A	3: 59,840,174 (GRCm39)		probably null	Het
Abca15	A	T	7: 119,987,456 (GRCm39)	Q1247H	possibly damaging	Het
Acsf2	G	C	11: 94,462,476 (GRCm39)	Q180E	probably benign	Het
Adamts8	A	G	9: 30,873,363 (GRCm39)	D856G	probably benign	Het
Agrn	A	T	4: 156,259,371 (GRCm39)	C828*	probably null	Het
Ankub1	T	C	3: 57,573,108 (GRCm39)	T205A	probably benign	Het
Atm	A	T	9: 53,373,803 (GRCm39)	Y2150N	possibly damaging	Het
Barhl1	A	G	2: 28,799,855 (GRCm39)	F257L	probably benign	Het
Bcat2	T	A	7: 45,224,909 (GRCm39)	C27S	probably benign	Het
Bod1l	G	A	5: 41,978,867 (GRCm39)	R816C	probably damaging	Het
Btg3	A	G	16: 78,161,695 (GRCm39)	Y172H	probably benign	Het
Cacna1d	T	C	14: 29,767,239 (GRCm39)	D1940G	probably benign	Het
Catsperg2	T	A	7: 29,406,026 (GRCm39)	N624I	possibly damaging	Het
Ccdc146	A	G	5: 21,508,110 (GRCm39)	V646A	probably benign	Het
Ccp110	C	T	7: 118,321,433 (GRCm39)	P363S	probably damaging	Het
Cct4	C	A	11: 22,951,564 (GRCm39)	T377K	possibly damaging	Het
Cemip2	C	A	19: 21,803,509 (GRCm39)	Y847*	probably null	Het
Cep350	T	A	1: 155,738,022 (GRCm39)	H2607L	probably benign	Het
Cfap46	A	G	7: 139,200,020 (GRCm39)	F1954L	unknown	Het
Chat	C	T	14: 32,145,213 (GRCm39)		probably null	Het
Clasp2	A	G	9: 113,705,421 (GRCm39)		probably null	Het
Cldn9	T	C	17: 23,901,989 (GRCm39)	D212G	probably benign	Het
Cp	G	A	3: 20,018,696 (GRCm39)		probably null	Het
Cyfip1	T	A	7: 55,576,148 (GRCm39)	I1108N	possibly damaging	Het
Dnah14	A	G	1: 181,625,299 (GRCm39)	D4060G	probably damaging	Het
Dpyd	A	G	3: 118,858,570 (GRCm39)	T595A	probably damaging	Het
Eps8	G	A	6: 137,486,211 (GRCm39)	R434C	possibly damaging	Het
Fasl	A	G	1: 161,615,557 (GRCm39)	Y100H	probably damaging	Het
Fkbp9	A	T	6: 56,826,712 (GRCm39)	N104I	probably damaging	Het
Frmd4a	A	G	2: 4,478,025 (GRCm39)	T65A	possibly damaging	Het
Gm1110	T	C	9: 26,825,653 (GRCm39)	N102S	probably damaging	Het
Gm2381	T	C	7: 42,471,804 (GRCm39)	Q25R	possibly damaging	Het
Gtpbp2	A	G	17: 46,472,239 (GRCm39)	Y58C	probably damaging	Het
H2-T3	C	A	17: 36,498,237 (GRCm39)	K269N	probably damaging	Het
Icosl	C	A	10: 77,909,707 (GRCm39)	Y217*	probably null	Het
Il17rd	G	T	14: 26,809,503 (GRCm39)	R153L	probably benign	Het
Kif17	C	A	4: 138,025,617 (GRCm39)	T973K	possibly damaging	Het
Klk1b16	A	G	7: 43,790,907 (GRCm39)	I236M	probably benign	Het
Lgmn	G	A	12: 102,389,998 (GRCm39)		probably benign	Het
Lmbr1l	T	C	15: 98,811,468 (GRCm39)	D54G	possibly damaging	Het
Lrrc49	A	T	9: 60,584,474 (GRCm39)	I196N	possibly damaging	Het
Maml1	C	T	11: 50,157,276 (GRCm39)	A300T	possibly damaging	Het
Mapkap1	A	T	2: 34,423,829 (GRCm39)	Q293L	possibly damaging	Het
Mki67	T	C	7: 135,315,568 (GRCm39)	T69A	probably benign	Het
Mlph	G	A	1: 90,849,705 (GRCm39)		probably null	Het
Myh1	A	T	11: 67,111,435 (GRCm39)	M1625L	probably benign	Het
Myh3	G	T	11: 66,981,847 (GRCm39)	R781L	probably benign	Het
Nckap5	A	T	1: 125,953,786 (GRCm39)	I922K	probably benign	Het
Nlrp5	T	A	7: 23,117,059 (GRCm39)	M261K	probably damaging	Het
Or1e1d-ps1	G	A	11: 73,819,663 (GRCm39)	M204I	probably benign	Het
Or4f47	A	T	2: 111,972,514 (GRCm39)	S75C	possibly damaging	Het
Or5af1	T	A	11: 58,722,750 (GRCm39)	Y257N	probably damaging	Het
Or8g52	A	G	9: 39,630,906 (GRCm39)	N128D	probably benign	Het
Pak1	T	A	7: 97,538,179 (GRCm39)	V262E	probably benign	Het
Pigw	A	T	11: 84,767,930 (GRCm39)	D466E	probably damaging	Het
Pira2	A	T	7: 3,847,344 (GRCm39)	L115Q	probably damaging	Het
Rbm15	A	C	3: 107,240,432 (GRCm39)		probably benign	Het
Rfx1	A	G	8: 84,800,385 (GRCm39)		probably benign	Het
Rfx7	A	G	9: 72,500,639 (GRCm39)	Y133C	probably damaging	Het
Serpinb9d	T	A	13: 33,384,702 (GRCm39)	D226E	probably benign	Het
Sgk3	G	A	1: 9,954,701 (GRCm39)	A271T	possibly damaging	Het
Sh2d5	T	A	4: 137,984,150 (GRCm39)	C173S	probably benign	Het
Skint8	T	C	4: 111,796,769 (GRCm39)	V291A	probably benign	Het
Slc22a27	T	A	19: 7,904,054 (GRCm39)	N28Y	probably benign	Het
Slc25a54	G	A	3: 109,023,751 (GRCm39)	V449I	probably benign	Het
Slc39a9	T	C	12: 80,726,316 (GRCm39)	F255S	probably damaging	Het
Spata31d1c	C	T	13: 65,183,942 (GRCm39)	H495Y	probably damaging	Het
Stab2	G	A	10: 86,805,049 (GRCm39)	Q310*	probably null	Het
Supt16	C	A	14: 52,408,948 (GRCm39)	A809S	possibly damaging	Het
Tex2	G	A	11: 106,439,685 (GRCm39)	T565M	unknown	Het
Tll1	G	A	8: 64,478,176 (GRCm39)	A859V	probably damaging	Het
Tmem106c	C	T	15: 97,867,512 (GRCm39)	T232I	possibly damaging	Het
Trim65	T	G	11: 116,019,116 (GRCm39)	D141A	probably benign	Het
Trim80	T	C	11: 115,332,042 (GRCm39)	F78S	probably damaging	Het
Txnrd1	T	A	10: 82,709,051 (GRCm39)	I83N	probably benign	Het
Vnn3	G	A	10: 23,727,806 (GRCm39)	G72D	probably benign	Het
Wasl	G	T	6: 24,619,686 (GRCm39)	P278Q	unknown	Het
Wdr62	A	T	7: 29,943,342 (GRCm39)	L951Q	probably damaging	Het
Zfp760	C	T	17: 21,942,814 (GRCm39)	T663I	unknown	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,870,095 (GRCm39)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,689,060 (GRCm39)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,732,077 (GRCm39)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,729,456 (GRCm39)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,870,167 (GRCm39)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,709,876 (GRCm39)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,689,458 (GRCm39)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,729,680 (GRCm39)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,681,837 (GRCm39)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,707,512 (GRCm39)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,689,793 (GRCm39)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,729,431 (GRCm39)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,729,611 (GRCm39)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,688,511 (GRCm39)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,689,729 (GRCm39)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,732,233 (GRCm39)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,741,051 (GRCm39)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,752,674 (GRCm39)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,751,991 (GRCm39)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,729,938 (GRCm39)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,751,913 (GRCm39)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	49,099,453 (GRCm39)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,688,558 (GRCm39)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,688,381 (GRCm39)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,688,642 (GRCm39)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,746,692 (GRCm39)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,796,380 (GRCm39)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,795,694 (GRCm39)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	49,127,507 (GRCm39)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	49,127,507 (GRCm39)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,689,755 (GRCm39)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,689,755 (GRCm39)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,794,069 (GRCm39)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,689,947 (GRCm39)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,685,140 (GRCm39)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,682,010 (GRCm39)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,740,826 (GRCm39)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,794,195 (GRCm39)	splice site	probably benign
R0573:Tenm3	UTSW	8	49,127,434 (GRCm39)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,730,745 (GRCm39)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,729,191 (GRCm39)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,689,560 (GRCm39)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,689,629 (GRCm39)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,788,777 (GRCm39)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,752,000 (GRCm39)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,681,577 (GRCm39)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,688,617 (GRCm39)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,693,431 (GRCm39)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,740,928 (GRCm39)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,729,435 (GRCm39)	missense	probably benign
R1455:Tenm3	UTSW	8	48,732,083 (GRCm39)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,689,006 (GRCm39)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,763,660 (GRCm39)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,796,351 (GRCm39)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,740,857 (GRCm39)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,848,611 (GRCm39)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,682,016 (GRCm39)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,689,456 (GRCm39)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,682,028 (GRCm39)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,732,109 (GRCm39)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,870,154 (GRCm39)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,763,669 (GRCm39)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,685,139 (GRCm39)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,870,214 (GRCm39)	missense	probably benign	0.05
R1793:Tenm3	UTSW	8	49,127,579 (GRCm39)	missense	probably damaging	0.98
R1801:Tenm3	UTSW	8	48,729,291 (GRCm39)	missense	probably benign	0.39
R1863:Tenm3	UTSW	8	48,729,381 (GRCm39)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,763,796 (GRCm39)	missense	probably damaging	1.00
R1971:Tenm3	UTSW	8	48,689,348 (GRCm39)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,681,626 (GRCm39)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,681,703 (GRCm39)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,795,291 (GRCm39)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,796,384 (GRCm39)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,870,041 (GRCm39)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,848,579 (GRCm39)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	49,127,585 (GRCm39)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,795,372 (GRCm39)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,729,693 (GRCm39)	missense	possibly damaging	0.87
R2419:Tenm3	UTSW	8	48,729,693 (GRCm39)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,740,988 (GRCm39)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,693,305 (GRCm39)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,681,590 (GRCm39)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,730,781 (GRCm39)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,802,258 (GRCm39)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,802,439 (GRCm39)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,848,693 (GRCm39)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,746,761 (GRCm39)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,689,005 (GRCm39)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,766,271 (GRCm39)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,763,656 (GRCm39)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,688,856 (GRCm39)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,729,896 (GRCm39)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,754,006 (GRCm39)	missense	probably damaging	1.00
R4962:Tenm3	UTSW	8	48,731,996 (GRCm39)	nonsense	probably null
R4995:Tenm3	UTSW	8	48,682,172 (GRCm39)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,688,861 (GRCm39)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,795,343 (GRCm39)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,689,390 (GRCm39)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,682,233 (GRCm39)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,689,890 (GRCm39)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,740,866 (GRCm39)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,689,390 (GRCm39)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,689,599 (GRCm39)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,820,412 (GRCm39)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,732,041 (GRCm39)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,689,799 (GRCm39)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,681,797 (GRCm39)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	49,099,533 (GRCm39)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	49,099,482 (GRCm39)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,681,543 (GRCm39)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,796,441 (GRCm39)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,848,608 (GRCm39)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,751,843 (GRCm39)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,707,657 (GRCm39)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,746,700 (GRCm39)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,870,094 (GRCm39)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,820,429 (GRCm39)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,729,884 (GRCm39)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,689,098 (GRCm39)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,870,257 (GRCm39)	missense	probably benign
R6516:Tenm3	UTSW	8	48,870,257 (GRCm39)	missense	probably benign
R6747:Tenm3	UTSW	8	48,796,278 (GRCm39)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	49,099,291 (GRCm39)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	49,127,528 (GRCm39)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,709,872 (GRCm39)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,729,773 (GRCm39)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,751,972 (GRCm39)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	49,127,451 (GRCm39)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,693,514 (GRCm39)	nonsense	probably null
R6968:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R6970:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,693,479 (GRCm39)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	49,127,588 (GRCm39)	missense	probably benign	0.00
R7140:Tenm3	UTSW	8	48,745,271 (GRCm39)	missense	probably damaging	1.00
R7222:Tenm3	UTSW	8	48,754,004 (GRCm39)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,688,970 (GRCm39)	missense	probably damaging	1.00
R7417:Tenm3	UTSW	8	48,689,218 (GRCm39)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,740,847 (GRCm39)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,729,635 (GRCm39)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,794,084 (GRCm39)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,788,762 (GRCm39)	missense	probably benign	0.27
R7734:Tenm3	UTSW	8	49,099,368 (GRCm39)	missense	probably damaging	1.00
R7802:Tenm3	UTSW	8	48,689,500 (GRCm39)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,729,335 (GRCm39)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,682,146 (GRCm39)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,763,738 (GRCm39)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,820,457 (GRCm39)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,746,808 (GRCm39)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,740,907 (GRCm39)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,740,883 (GRCm39)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,746,544 (GRCm39)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,740,907 (GRCm39)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,682,216 (GRCm39)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,795,668 (GRCm39)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,752,680 (GRCm39)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,802,391 (GRCm39)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,795,484 (GRCm39)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,763,759 (GRCm39)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,729,417 (GRCm39)	missense
R8831:Tenm3	UTSW	8	48,729,417 (GRCm39)	missense
R8853:Tenm3	UTSW	8	48,795,382 (GRCm39)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,689,437 (GRCm39)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,688,637 (GRCm39)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,732,095 (GRCm39)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,688,383 (GRCm39)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,729,722 (GRCm39)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,795,688 (GRCm39)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,707,668 (GRCm39)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,745,186 (GRCm39)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,766,271 (GRCm39)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,788,548 (GRCm39)	missense	unknown
R9231:Tenm3	UTSW	8	48,689,231 (GRCm39)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,751,972 (GRCm39)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	49,008,935 (GRCm39)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,870,115 (GRCm39)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,752,690 (GRCm39)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	49,127,559 (GRCm39)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,766,292 (GRCm39)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,688,796 (GRCm39)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,689,246 (GRCm39)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,753,849 (GRCm39)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,788,596 (GRCm39)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,740,864 (GRCm39)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,689,512 (GRCm39)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,729,815 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTCTGTCGCGCAGGTCATAG -3'
(R):5'- GACATCTCTGGCAAAGTCGAGC -3'

Sequencing Primer
(F):5'- TCATAGCGCAGAGGGGTC -3'
(R):5'- CTCTGGCAAAGTCGAGCAGTTTG -3'

Posted On

2019-09-13