Incidental Mutation 'R7337:Ecpas'
| ID |
569558 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ecpas
|
| Ensembl Gene |
ENSMUSG00000050812 |
| Gene Name |
Ecm29 proteasome adaptor and scaffold |
| Synonyms |
AI314180 |
| MMRRC Submission |
045427-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.366)
|
| Stock # |
R7337 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
58798911-58912749 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 58827047 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1029
(T1029A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099953
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000102889]
[ENSMUST00000107557]
[ENSMUST00000149301]
|
| AlphaFold |
Q6PDI5 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000102889
AA Change: T1029A
PolyPhen 2
Score 0.685 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000099953
Gene: ENSMUSG00000050812
AA Change: T1029A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Ecm29
|
10 |
517 |
1.1e-155 |
PFAM |
|
low complexity region
|
627 |
642 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
665 |
N/A |
INTRINSIC |
|
SCOP:d1qbkb_
|
693 |
1491 |
3e-31 |
SMART |
|
low complexity region
|
1781 |
1797 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107557
|
| SMART Domains |
Protein: ENSMUSP00000103182
Gene: ENSMUSG00000050812
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Ecm29
|
10 |
517 |
7.6e-164 |
PFAM |
|
low complexity region
|
627 |
642 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
665 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135601
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149301
AA Change: T1029A
PolyPhen 2
Score 0.370 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000117585
Gene: ENSMUSG00000050812
AA Change: T1029A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Ecm29
|
10 |
517 |
4e-163 |
PFAM |
|
low complexity region
|
627 |
642 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
665 |
N/A |
INTRINSIC |
|
SCOP:d1qbkb_
|
693 |
1490 |
8e-32 |
SMART |
|
| Meta Mutation Damage Score |
0.0755 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (88/88) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb11 |
A |
T |
2: 69,076,113 (GRCm39) |
H1198Q |
probably damaging |
Het |
| Adamts14 |
A |
G |
10: 61,043,239 (GRCm39) |
V743A |
probably damaging |
Het |
| Adgrg6 |
A |
G |
10: 14,343,095 (GRCm39) |
V284A |
possibly damaging |
Het |
| Alb |
A |
G |
5: 90,622,452 (GRCm39) |
K560R |
probably damaging |
Het |
| Aqp9 |
A |
T |
9: 71,069,764 (GRCm39) |
F8L |
probably benign |
Het |
| Arhgef7 |
T |
C |
8: 11,835,789 (GRCm39) |
L182P |
probably damaging |
Het |
| Atr |
A |
G |
9: 95,753,501 (GRCm39) |
D701G |
probably damaging |
Het |
| Calr3 |
C |
T |
8: 73,185,339 (GRCm39) |
D187N |
probably damaging |
Het |
| Ccdc198 |
A |
G |
14: 49,471,948 (GRCm39) |
M163T |
possibly damaging |
Het |
| Ccdc65 |
A |
G |
15: 98,618,977 (GRCm39) |
T319A |
probably benign |
Het |
| Ccdc66 |
A |
T |
14: 27,222,290 (GRCm39) |
L151H |
probably damaging |
Het |
| Ces2e |
T |
A |
8: 105,657,688 (GRCm39) |
|
probably null |
Het |
| Cfap46 |
A |
G |
7: 139,210,492 (GRCm39) |
|
probably null |
Het |
| Cfap74 |
A |
G |
4: 155,544,472 (GRCm39) |
T1034A |
unknown |
Het |
| Cldnd1 |
T |
G |
16: 58,549,322 (GRCm39) |
|
probably null |
Het |
| Clec4f |
C |
A |
6: 83,630,190 (GRCm39) |
V123L |
probably benign |
Het |
| Cntn6 |
C |
T |
6: 104,627,491 (GRCm39) |
T108I |
probably damaging |
Het |
| Crygn |
T |
G |
5: 24,961,147 (GRCm39) |
D53A |
possibly damaging |
Het |
| Cyp27a1 |
T |
A |
1: 74,774,594 (GRCm39) |
V204E |
probably damaging |
Het |
| Cyp2c67 |
A |
T |
19: 39,597,708 (GRCm39) |
|
probably null |
Het |
| Ddb1 |
T |
C |
19: 10,605,195 (GRCm39) |
V1061A |
possibly damaging |
Het |
| Dnah12 |
G |
T |
14: 26,488,534 (GRCm39) |
|
probably null |
Het |
| Draxin |
T |
C |
4: 148,197,216 (GRCm39) |
T194A |
probably benign |
Het |
| Drosha |
T |
A |
15: 12,846,285 (GRCm39) |
D473E |
possibly damaging |
Het |
| G6pd2 |
T |
A |
5: 61,967,562 (GRCm39) |
C446S |
probably benign |
Het |
| Gm29106 |
C |
T |
1: 118,104,642 (GRCm39) |
S3L |
unknown |
Het |
| Grin3a |
T |
C |
4: 49,702,762 (GRCm39) |
Y908C |
probably damaging |
Het |
| Ints2 |
G |
A |
11: 86,108,668 (GRCm39) |
A893V |
probably benign |
Het |
| Ippk |
C |
T |
13: 49,602,767 (GRCm39) |
T371I |
probably benign |
Het |
| Irf2 |
T |
A |
8: 47,260,316 (GRCm39) |
C83S |
probably damaging |
Het |
| Jph3 |
C |
T |
8: 122,480,441 (GRCm39) |
A373V |
probably benign |
Het |
| Kcnj6 |
C |
T |
16: 94,634,073 (GRCm39) |
V13I |
probably benign |
Het |
| Lama3 |
T |
C |
18: 12,640,097 (GRCm39) |
|
probably null |
Het |
| Lmo7 |
A |
T |
14: 102,121,640 (GRCm39) |
Q235L |
probably damaging |
Het |
| Marchf7 |
A |
G |
2: 60,071,189 (GRCm39) |
|
probably null |
Het |
| Mfsd6l |
A |
T |
11: 68,448,109 (GRCm39) |
Y320F |
possibly damaging |
Het |
| Mroh1 |
T |
A |
15: 76,335,676 (GRCm39) |
W1440R |
probably benign |
Het |
| Mrps17 |
G |
A |
5: 129,793,863 (GRCm39) |
G19D |
probably damaging |
Het |
| Myt1 |
A |
G |
2: 181,444,756 (GRCm39) |
H566R |
possibly damaging |
Het |
| Nav2 |
T |
C |
7: 49,201,521 (GRCm39) |
L176P |
possibly damaging |
Het |
| Nop58 |
T |
A |
1: 59,737,599 (GRCm39) |
C139S |
probably benign |
Het |
| Nsd1 |
A |
G |
13: 55,394,022 (GRCm39) |
D644G |
probably damaging |
Het |
| Nsd2 |
T |
A |
5: 34,042,816 (GRCm39) |
C1027S |
probably damaging |
Het |
| Nsmce2 |
A |
G |
15: 59,473,265 (GRCm39) |
I235V |
probably damaging |
Het |
| Nyap2 |
T |
C |
1: 81,314,230 (GRCm39) |
V642A |
possibly damaging |
Het |
| Or14n1-ps1 |
A |
T |
7: 86,092,328 (GRCm39) |
L46F |
unknown |
Het |
| Or8g51 |
A |
G |
9: 38,609,161 (GRCm39) |
V167A |
probably benign |
Het |
| Paqr7 |
A |
G |
4: 134,234,431 (GRCm39) |
D96G |
probably benign |
Het |
| Parp4 |
A |
G |
14: 56,839,852 (GRCm39) |
Y520C |
probably damaging |
Het |
| Pde5a |
A |
G |
3: 122,542,107 (GRCm39) |
N199S |
probably damaging |
Het |
| Piezo1 |
A |
T |
8: 123,212,463 (GRCm39) |
Y1955N |
|
Het |
| Pnma8a |
A |
G |
7: 16,695,315 (GRCm39) |
K390R |
probably benign |
Het |
| Prdm10 |
G |
T |
9: 31,227,537 (GRCm39) |
Q47H |
probably damaging |
Het |
| Psg22 |
T |
A |
7: 18,453,499 (GRCm39) |
F104I |
probably benign |
Het |
| Ptprf |
T |
C |
4: 118,068,322 (GRCm39) |
E1738G |
probably damaging |
Het |
| Rad21l |
A |
T |
2: 151,500,365 (GRCm39) |
L218Q |
probably damaging |
Het |
| Rad54l2 |
A |
G |
9: 106,583,024 (GRCm39) |
I798T |
probably damaging |
Het |
| Rgs5 |
G |
T |
1: 169,483,149 (GRCm39) |
M1I |
probably null |
Het |
| Rhbdl2 |
T |
C |
4: 123,711,659 (GRCm39) |
V132A |
possibly damaging |
Het |
| Rmi1 |
T |
A |
13: 58,557,393 (GRCm39) |
Y547* |
probably null |
Het |
| Rptn |
A |
T |
3: 93,304,212 (GRCm39) |
D515V |
probably benign |
Het |
| Rsph10b |
A |
G |
5: 143,898,033 (GRCm39) |
N505D |
probably benign |
Het |
| Samhd1 |
T |
C |
2: 156,948,164 (GRCm39) |
D539G |
probably damaging |
Het |
| Scube3 |
A |
T |
17: 28,387,156 (GRCm39) |
I885F |
probably damaging |
Het |
| Sfmbt1 |
A |
G |
14: 30,506,696 (GRCm39) |
I247V |
possibly damaging |
Het |
| Slc25a21 |
T |
C |
12: 56,904,828 (GRCm39) |
I62V |
probably benign |
Het |
| Slc4a11 |
T |
A |
2: 130,527,452 (GRCm39) |
N648Y |
probably damaging |
Het |
| Slc7a11 |
A |
G |
3: 50,397,448 (GRCm39) |
V88A |
possibly damaging |
Het |
| Slc7a8 |
A |
C |
14: 54,964,263 (GRCm39) |
F397V |
possibly damaging |
Het |
| Sox12 |
A |
C |
2: 152,239,377 (GRCm39) |
L81R |
probably damaging |
Het |
| Spg11 |
T |
C |
2: 121,915,474 (GRCm39) |
I1057V |
probably benign |
Het |
| St8sia3 |
G |
A |
18: 64,402,987 (GRCm39) |
V265I |
probably benign |
Het |
| Stxbp5 |
A |
G |
10: 9,684,874 (GRCm39) |
S509P |
possibly damaging |
Het |
| Svep1 |
T |
C |
4: 58,108,323 (GRCm39) |
Y1129C |
probably damaging |
Het |
| Tenm4 |
G |
T |
7: 96,523,333 (GRCm39) |
R1625L |
probably benign |
Het |
| Tlr4 |
T |
C |
4: 66,758,191 (GRCm39) |
F328S |
possibly damaging |
Het |
| Tmprss15 |
T |
C |
16: 78,868,164 (GRCm39) |
T215A |
probably benign |
Het |
| Tmprss9 |
A |
T |
10: 80,718,504 (GRCm39) |
I62L |
probably benign |
Het |
| Trpm5 |
C |
T |
7: 142,642,756 (GRCm39) |
A64T |
probably benign |
Het |
| Txk |
A |
C |
5: 72,889,109 (GRCm39) |
Y148* |
probably null |
Het |
| Uba5 |
C |
T |
9: 103,932,454 (GRCm39) |
G170R |
possibly damaging |
Het |
| Uggt2 |
A |
T |
14: 119,323,587 (GRCm39) |
D231E |
probably benign |
Het |
| Ulk4 |
A |
T |
9: 121,077,993 (GRCm39) |
D525E |
probably benign |
Het |
| Vmn1r158 |
T |
A |
7: 22,489,649 (GRCm39) |
T187S |
probably benign |
Het |
| Vmn1r52 |
T |
A |
6: 90,156,605 (GRCm39) |
M303K |
probably benign |
Het |
| Vmn2r54 |
A |
G |
7: 12,356,044 (GRCm39) |
F454S |
probably benign |
Het |
| Zbp1 |
A |
T |
2: 173,060,546 (GRCm39) |
L8* |
probably null |
Het |
| Zmym2 |
A |
T |
14: 57,181,557 (GRCm39) |
D924V |
probably benign |
Het |
|
| Other mutations in Ecpas |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00799:Ecpas
|
APN |
4 |
58,828,047 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01145:Ecpas
|
APN |
4 |
58,811,501 (GRCm39) |
missense |
probably null |
0.08 |
|
IGL01371:Ecpas
|
APN |
4 |
58,809,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01445:Ecpas
|
APN |
4 |
58,833,988 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01452:Ecpas
|
APN |
4 |
58,836,181 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01626:Ecpas
|
APN |
4 |
58,832,814 (GRCm39) |
splice site |
probably benign |
|
|
IGL01672:Ecpas
|
APN |
4 |
58,814,041 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL01943:Ecpas
|
APN |
4 |
58,849,937 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01944:Ecpas
|
APN |
4 |
58,861,544 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL02190:Ecpas
|
APN |
4 |
58,800,190 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL02272:Ecpas
|
APN |
4 |
58,811,731 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02435:Ecpas
|
APN |
4 |
58,830,325 (GRCm39) |
splice site |
probably benign |
|
|
IGL02516:Ecpas
|
APN |
4 |
58,877,102 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Ecpas
|
APN |
4 |
58,805,534 (GRCm39) |
splice site |
probably benign |
|
|
IGL02709:Ecpas
|
APN |
4 |
58,872,699 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02742:Ecpas
|
APN |
4 |
58,840,757 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02812:Ecpas
|
APN |
4 |
58,864,343 (GRCm39) |
splice site |
probably benign |
|
|
IGL02828:Ecpas
|
APN |
4 |
58,875,512 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL03130:Ecpas
|
APN |
4 |
58,800,288 (GRCm39) |
missense |
probably benign |
|
|
IGL03179:Ecpas
|
APN |
4 |
58,832,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03237:Ecpas
|
APN |
4 |
58,810,668 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL03344:Ecpas
|
APN |
4 |
58,828,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
boone
|
UTSW |
4 |
58,877,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Crockett
|
UTSW |
4 |
58,879,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
frontiersman
|
UTSW |
4 |
58,832,753 (GRCm39) |
missense |
probably benign |
|
|
BB006:Ecpas
|
UTSW |
4 |
58,869,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB016:Ecpas
|
UTSW |
4 |
58,869,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0051:Ecpas
|
UTSW |
4 |
58,832,729 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0051:Ecpas
|
UTSW |
4 |
58,832,729 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0313:Ecpas
|
UTSW |
4 |
58,811,892 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0399:Ecpas
|
UTSW |
4 |
58,827,047 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0487:Ecpas
|
UTSW |
4 |
58,819,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0492:Ecpas
|
UTSW |
4 |
58,864,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0705:Ecpas
|
UTSW |
4 |
58,885,366 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0847:Ecpas
|
UTSW |
4 |
58,841,439 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1467:Ecpas
|
UTSW |
4 |
58,832,753 (GRCm39) |
missense |
probably benign |
|
|
R1467:Ecpas
|
UTSW |
4 |
58,832,753 (GRCm39) |
missense |
probably benign |
|
|
R1482:Ecpas
|
UTSW |
4 |
58,820,163 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1529:Ecpas
|
UTSW |
4 |
58,832,701 (GRCm39) |
splice site |
probably null |
|
|
R1771:Ecpas
|
UTSW |
4 |
58,879,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1776:Ecpas
|
UTSW |
4 |
58,879,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1822:Ecpas
|
UTSW |
4 |
58,805,539 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1864:Ecpas
|
UTSW |
4 |
58,849,942 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R2029:Ecpas
|
UTSW |
4 |
58,844,165 (GRCm39) |
nonsense |
probably null |
|
|
R2061:Ecpas
|
UTSW |
4 |
58,824,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2125:Ecpas
|
UTSW |
4 |
58,833,978 (GRCm39) |
missense |
probably benign |
|
|
R2266:Ecpas
|
UTSW |
4 |
58,830,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2889:Ecpas
|
UTSW |
4 |
58,836,165 (GRCm39) |
missense |
probably benign |
|
|
R2902:Ecpas
|
UTSW |
4 |
58,809,691 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2903:Ecpas
|
UTSW |
4 |
58,828,622 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2925:Ecpas
|
UTSW |
4 |
58,833,928 (GRCm39) |
nonsense |
probably null |
|
|
R4151:Ecpas
|
UTSW |
4 |
58,836,254 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4225:Ecpas
|
UTSW |
4 |
58,847,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4486:Ecpas
|
UTSW |
4 |
58,820,086 (GRCm39) |
intron |
probably benign |
|
|
R4576:Ecpas
|
UTSW |
4 |
58,834,708 (GRCm39) |
intron |
probably benign |
|
|
R4580:Ecpas
|
UTSW |
4 |
58,840,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4654:Ecpas
|
UTSW |
4 |
58,834,523 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4688:Ecpas
|
UTSW |
4 |
58,840,757 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4726:Ecpas
|
UTSW |
4 |
58,844,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Ecpas
|
UTSW |
4 |
58,850,911 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4928:Ecpas
|
UTSW |
4 |
58,827,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5098:Ecpas
|
UTSW |
4 |
58,877,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5284:Ecpas
|
UTSW |
4 |
58,836,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5375:Ecpas
|
UTSW |
4 |
58,809,401 (GRCm39) |
nonsense |
probably null |
|
|
R5382:Ecpas
|
UTSW |
4 |
58,850,934 (GRCm39) |
missense |
probably benign |
0.38 |
|
R5487:Ecpas
|
UTSW |
4 |
58,809,421 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5703:Ecpas
|
UTSW |
4 |
58,877,171 (GRCm39) |
splice site |
probably null |
|
|
R5761:Ecpas
|
UTSW |
4 |
58,853,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5791:Ecpas
|
UTSW |
4 |
58,822,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5791:Ecpas
|
UTSW |
4 |
58,814,027 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5928:Ecpas
|
UTSW |
4 |
58,849,948 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R6062:Ecpas
|
UTSW |
4 |
58,826,453 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6246:Ecpas
|
UTSW |
4 |
58,811,365 (GRCm39) |
splice site |
probably null |
|
|
R6298:Ecpas
|
UTSW |
4 |
58,877,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6326:Ecpas
|
UTSW |
4 |
58,827,068 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6478:Ecpas
|
UTSW |
4 |
58,810,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6707:Ecpas
|
UTSW |
4 |
58,879,101 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R6846:Ecpas
|
UTSW |
4 |
58,814,081 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6857:Ecpas
|
UTSW |
4 |
58,814,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6951:Ecpas
|
UTSW |
4 |
58,853,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7088:Ecpas
|
UTSW |
4 |
58,849,766 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7302:Ecpas
|
UTSW |
4 |
58,834,593 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7341:Ecpas
|
UTSW |
4 |
58,809,415 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7344:Ecpas
|
UTSW |
4 |
58,824,770 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7525:Ecpas
|
UTSW |
4 |
58,847,038 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7530:Ecpas
|
UTSW |
4 |
58,815,317 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7533:Ecpas
|
UTSW |
4 |
58,809,411 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7557:Ecpas
|
UTSW |
4 |
58,849,691 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7698:Ecpas
|
UTSW |
4 |
58,832,660 (GRCm39) |
missense |
unknown |
|
|
R7793:Ecpas
|
UTSW |
4 |
58,853,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7892:Ecpas
|
UTSW |
4 |
58,828,593 (GRCm39) |
missense |
probably benign |
|
|
R7894:Ecpas
|
UTSW |
4 |
58,853,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7929:Ecpas
|
UTSW |
4 |
58,869,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8010:Ecpas
|
UTSW |
4 |
58,832,681 (GRCm39) |
missense |
unknown |
|
|
R8082:Ecpas
|
UTSW |
4 |
58,807,852 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8175:Ecpas
|
UTSW |
4 |
58,872,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8191:Ecpas
|
UTSW |
4 |
58,872,587 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8326:Ecpas
|
UTSW |
4 |
58,847,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8459:Ecpas
|
UTSW |
4 |
58,821,379 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8683:Ecpas
|
UTSW |
4 |
58,834,515 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8747:Ecpas
|
UTSW |
4 |
58,828,632 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8981:Ecpas
|
UTSW |
4 |
58,801,796 (GRCm39) |
missense |
probably benign |
|
|
R9206:Ecpas
|
UTSW |
4 |
58,875,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9208:Ecpas
|
UTSW |
4 |
58,875,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Ecpas
|
UTSW |
4 |
58,875,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9249:Ecpas
|
UTSW |
4 |
58,869,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9355:Ecpas
|
UTSW |
4 |
58,844,114 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9534:Ecpas
|
UTSW |
4 |
58,807,867 (GRCm39) |
missense |
probably benign |
|
|
R9555:Ecpas
|
UTSW |
4 |
58,879,083 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9570:Ecpas
|
UTSW |
4 |
58,832,796 (GRCm39) |
nonsense |
probably null |
|
|
R9673:Ecpas
|
UTSW |
4 |
58,822,060 (GRCm39) |
missense |
probably benign |
|
|
R9707:Ecpas
|
UTSW |
4 |
58,824,816 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9721:Ecpas
|
UTSW |
4 |
58,850,938 (GRCm39) |
missense |
probably benign |
0.39 |
|
X0060:Ecpas
|
UTSW |
4 |
58,840,752 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
Z1177:Ecpas
|
UTSW |
4 |
58,861,614 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCAATGCTTTAACTGTCATAGGAC -3'
(R):5'- GGGTGTCTTAAAGTCCTAGGAGAG -3'
Sequencing Primer
(F):5'- GTAAACAGTATACACTGGGAT -3'
(R):5'- ATTGAGGATTTCTTGTCCATTGAC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation