Incidental Mutation 'R7341:Ccdc180'
| ID |
569834 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc180
|
| Ensembl Gene |
ENSMUSG00000035539 |
| Gene Name |
coiled-coil domain containing 180 |
| Synonyms |
LOC381522, E230008N13Rik |
| MMRRC Submission |
045431-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7341 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
45890303-45950774 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 45898644 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 164
(E164G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136714
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000178561]
|
| AlphaFold |
J3QNE4 |
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000119784
Gene: ENSMUSG00000035539
AA Change: E156G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
42 |
N/A |
INTRINSIC |
|
coiled coil region
|
90 |
117 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
141 |
609 |
2e-189 |
PFAM |
|
low complexity region
|
628 |
642 |
N/A |
INTRINSIC |
|
low complexity region
|
658 |
675 |
N/A |
INTRINSIC |
|
coiled coil region
|
710 |
780 |
N/A |
INTRINSIC |
|
coiled coil region
|
945 |
979 |
N/A |
INTRINSIC |
|
low complexity region
|
1100 |
1123 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1169 |
1372 |
9.5e-77 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000178561
AA Change: E164G
PolyPhen 2
Score 0.847 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000136714
Gene: ENSMUSG00000035539
AA Change: E164G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
49 |
N/A |
INTRINSIC |
|
coiled coil region
|
98 |
125 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
148 |
616 |
7.3e-189 |
PFAM |
|
low complexity region
|
635 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
682 |
N/A |
INTRINSIC |
|
coiled coil region
|
718 |
788 |
N/A |
INTRINSIC |
|
coiled coil region
|
1121 |
1155 |
N/A |
INTRINSIC |
|
low complexity region
|
1275 |
1298 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1344 |
1547 |
2.2e-76 |
PFAM |
|
| Meta Mutation Damage Score |
0.0845 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
100% (92/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a coiled-coil domain. Alternative splicing results in multiple transcript variants encoding different isoforms. A single nucleotide polymorphism (SNP) in this gene has been associated with increased susceptibility to Behcet's Disease (PMID: 19442274). [provided by RefSeq, Dec 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb11 |
C |
T |
2: 69,130,211 (GRCm39) |
D282N |
probably damaging |
Het |
| Adam3 |
T |
A |
8: 25,177,996 (GRCm39) |
N639I |
possibly damaging |
Het |
| Adamtsl3 |
T |
A |
7: 82,206,082 (GRCm39) |
C756S |
probably damaging |
Het |
| Arhgap31 |
C |
T |
16: 38,532,876 (GRCm39) |
|
probably null |
Het |
| Ascl4 |
G |
A |
10: 85,764,529 (GRCm39) |
A59T |
possibly damaging |
Het |
| Ash1l |
T |
A |
3: 88,889,066 (GRCm39) |
I315N |
possibly damaging |
Het |
| Atp6v0d2 |
T |
C |
4: 19,887,330 (GRCm39) |
D206G |
possibly damaging |
Het |
| Baz1b |
T |
A |
5: 135,251,970 (GRCm39) |
L923I |
probably damaging |
Het |
| Birc6 |
T |
A |
17: 74,919,069 (GRCm39) |
N1966K |
probably damaging |
Het |
| Bod1l |
T |
C |
5: 41,946,200 (GRCm39) |
N3025S |
probably benign |
Het |
| Bub1b |
C |
A |
2: 118,467,267 (GRCm39) |
H863Q |
possibly damaging |
Het |
| C1rb |
T |
A |
6: 124,554,411 (GRCm39) |
Y397* |
probably null |
Het |
| Ccdc9 |
C |
T |
7: 16,014,552 (GRCm39) |
V230M |
probably damaging |
Het |
| Cchcr1 |
C |
A |
17: 35,837,610 (GRCm39) |
N437K |
probably benign |
Het |
| Cdhr2 |
T |
A |
13: 54,867,305 (GRCm39) |
L408Q |
probably damaging |
Het |
| Cep89 |
G |
A |
7: 35,129,353 (GRCm39) |
R630H |
probably damaging |
Het |
| Chd1 |
T |
C |
17: 15,990,499 (GRCm39) |
S1684P |
probably damaging |
Het |
| CN725425 |
A |
G |
15: 91,126,873 (GRCm39) |
Y221C |
possibly damaging |
Het |
| Col4a2 |
T |
C |
8: 11,448,678 (GRCm39) |
V66A |
probably damaging |
Het |
| Cpd |
C |
A |
11: 76,737,779 (GRCm39) |
R5L |
unknown |
Het |
| Cpeb4 |
C |
T |
11: 31,868,807 (GRCm39) |
T422I |
possibly damaging |
Het |
| Cspg4b |
G |
T |
13: 113,454,706 (GRCm39) |
G251C |
|
Het |
| Cyp1a1 |
G |
T |
9: 57,608,107 (GRCm39) |
R245L |
probably damaging |
Het |
| Cyp4f39 |
A |
G |
17: 32,705,928 (GRCm39) |
T340A |
probably damaging |
Het |
| Cyp4v3 |
A |
T |
8: 45,774,787 (GRCm39) |
F122L |
probably benign |
Het |
| Drc1 |
T |
A |
5: 30,521,812 (GRCm39) |
L728Q |
probably damaging |
Het |
| Dsel |
C |
T |
1: 111,789,303 (GRCm39) |
G411S |
probably damaging |
Het |
| Ecpas |
A |
T |
4: 58,809,415 (GRCm39) |
V1653D |
possibly damaging |
Het |
| Ermp1 |
T |
A |
19: 29,623,654 (GRCm39) |
H112L |
probably benign |
Het |
| Exoc8 |
T |
C |
8: 125,623,320 (GRCm39) |
D349G |
probably damaging |
Het |
| Fam151a |
T |
A |
4: 106,592,707 (GRCm39) |
M63K |
probably benign |
Het |
| Fmo9 |
C |
A |
1: 166,504,115 (GRCm39) |
G149V |
probably damaging |
Het |
| Fndc8 |
A |
G |
11: 82,789,603 (GRCm39) |
T254A |
possibly damaging |
Het |
| Foxi3 |
G |
A |
6: 70,937,862 (GRCm39) |
V365I |
probably benign |
Het |
| Frem2 |
C |
T |
3: 53,561,916 (GRCm39) |
G864S |
probably damaging |
Het |
| Fstl5 |
T |
A |
3: 76,389,704 (GRCm39) |
|
probably null |
Het |
| Garnl3 |
T |
A |
2: 32,924,141 (GRCm39) |
E247V |
probably damaging |
Het |
| Gdi1 |
G |
A |
X: 73,350,461 (GRCm39) |
R55H |
probably benign |
Het |
| Gorasp1 |
T |
A |
9: 119,766,600 (GRCm39) |
|
probably benign |
Het |
| Hcar2 |
T |
C |
5: 124,002,541 (GRCm39) |
N321D |
possibly damaging |
Het |
| Hoxb6 |
G |
T |
11: 96,190,395 (GRCm39) |
M131I |
probably damaging |
Het |
| Kif13a |
A |
G |
13: 46,980,221 (GRCm39) |
V177A |
probably damaging |
Het |
| Limch1 |
C |
T |
5: 67,191,545 (GRCm39) |
T794I |
probably benign |
Het |
| Lmbrd2 |
A |
G |
15: 9,165,906 (GRCm39) |
Y260C |
possibly damaging |
Het |
| Lmo7 |
A |
G |
14: 102,122,948 (GRCm39) |
N379S |
probably benign |
Het |
| Lrp6 |
G |
T |
6: 134,427,781 (GRCm39) |
P1604T |
probably damaging |
Het |
| Lrrc14 |
A |
T |
15: 76,598,711 (GRCm39) |
E449V |
probably damaging |
Het |
| Lrrc8c |
T |
C |
5: 105,755,133 (GRCm39) |
Y303H |
probably damaging |
Het |
| Mecr |
T |
G |
4: 131,570,986 (GRCm39) |
V58G |
probably null |
Het |
| Med12l |
T |
A |
3: 58,949,824 (GRCm39) |
D193E |
possibly damaging |
Het |
| Moap1 |
T |
C |
12: 102,709,438 (GRCm39) |
E37G |
probably damaging |
Het |
| Mrgprb2 |
T |
A |
7: 48,202,644 (GRCm39) |
Y27F |
probably benign |
Het |
| Ms4a6d |
G |
A |
19: 11,567,437 (GRCm39) |
Q155* |
probably null |
Het |
| Ndufs5 |
A |
T |
4: 123,609,744 (GRCm39) |
C43* |
probably null |
Het |
| Oaz2 |
A |
T |
9: 65,596,183 (GRCm39) |
D83V |
|
Het |
| Or2t29 |
A |
T |
11: 58,433,533 (GRCm39) |
Y269* |
probably null |
Het |
| Or5ac22 |
T |
A |
16: 59,135,512 (GRCm39) |
N86I |
possibly damaging |
Het |
| Palm |
A |
G |
10: 79,652,697 (GRCm39) |
T191A |
probably damaging |
Het |
| Pclo |
C |
A |
5: 14,725,850 (GRCm39) |
D1569E |
unknown |
Het |
| Ppid |
T |
A |
3: 79,507,604 (GRCm39) |
D264E |
probably benign |
Het |
| Ppp1r3a |
A |
G |
6: 14,718,749 (GRCm39) |
S722P |
probably damaging |
Het |
| Ranbp2 |
A |
G |
10: 58,321,619 (GRCm39) |
S2639G |
possibly damaging |
Het |
| Rbak |
T |
C |
5: 143,161,827 (GRCm39) |
T68A |
probably benign |
Het |
| Rbm15b |
C |
T |
9: 106,762,246 (GRCm39) |
G641R |
probably benign |
Het |
| Rgsl1 |
A |
G |
1: 153,669,591 (GRCm39) |
I265T |
probably benign |
Het |
| Rmdn1 |
T |
A |
4: 19,586,837 (GRCm39) |
Y98* |
probably null |
Het |
| Sfxn3 |
T |
G |
19: 45,037,701 (GRCm39) |
N52K |
probably benign |
Het |
| Slc17a3 |
G |
T |
13: 24,030,867 (GRCm39) |
G182* |
probably null |
Het |
| Slc29a3 |
A |
T |
10: 60,586,437 (GRCm39) |
Y10N |
probably benign |
Het |
| Slc43a1 |
T |
C |
2: 84,693,278 (GRCm39) |
Y577H |
probably damaging |
Het |
| Smarcd3 |
T |
A |
5: 24,800,435 (GRCm39) |
I210F |
possibly damaging |
Het |
| Snapc4 |
A |
T |
2: 26,259,273 (GRCm39) |
S626T |
probably benign |
Het |
| Sp5 |
T |
A |
2: 70,307,041 (GRCm39) |
L242* |
probably null |
Het |
| Spata25 |
C |
G |
2: 164,669,582 (GRCm39) |
G143A |
probably damaging |
Het |
| Spata6 |
T |
A |
4: 111,625,935 (GRCm39) |
Y101* |
probably null |
Het |
| Tdp2 |
T |
G |
13: 25,016,059 (GRCm39) |
S89A |
probably benign |
Het |
| Tlr6 |
T |
C |
5: 65,110,972 (GRCm39) |
E645G |
probably benign |
Het |
| Tmem209 |
T |
C |
6: 30,494,794 (GRCm39) |
I355V |
probably benign |
Het |
| Trappc8 |
A |
T |
18: 20,985,704 (GRCm39) |
Y646N |
probably damaging |
Het |
| Tspoap1 |
A |
G |
11: 87,657,205 (GRCm39) |
N399S |
probably damaging |
Het |
| Ube4b |
A |
G |
4: 149,427,458 (GRCm39) |
Y897H |
probably damaging |
Het |
| Urb1 |
CACTTAC |
CAC |
16: 90,569,461 (GRCm39) |
|
probably benign |
Het |
| Usp9y |
A |
T |
Y: 1,315,759 (GRCm39) |
|
probably null |
Het |
| Vmn2r1 |
T |
C |
3: 64,012,877 (GRCm39) |
*913Q |
probably null |
Het |
| Vmn2r12 |
T |
A |
5: 109,234,113 (GRCm39) |
T700S |
possibly damaging |
Het |
| Vmn2r12 |
C |
T |
5: 109,239,811 (GRCm39) |
A251T |
possibly damaging |
Het |
| Wdr70 |
A |
C |
15: 7,953,725 (GRCm39) |
F389V |
possibly damaging |
Het |
| Wdr91 |
A |
T |
6: 34,868,395 (GRCm39) |
M442K |
possibly damaging |
Het |
| Ydjc |
T |
C |
16: 16,968,762 (GRCm39) |
C234R |
probably benign |
Het |
| Zfp87 |
A |
G |
13: 74,520,467 (GRCm39) |
Y204H |
possibly damaging |
Het |
|
| Other mutations in Ccdc180 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01369:Ccdc180
|
APN |
4 |
45,900,256 (GRCm39) |
missense |
probably benign |
|
|
IGL01713:Ccdc180
|
APN |
4 |
45,921,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01915:Ccdc180
|
APN |
4 |
45,904,544 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01935:Ccdc180
|
APN |
4 |
45,906,889 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02539:Ccdc180
|
APN |
4 |
45,921,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02982:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03071:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03146:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
PIT4687001:Ccdc180
|
UTSW |
4 |
45,949,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0080:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0082:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0126:Ccdc180
|
UTSW |
4 |
45,912,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0193:Ccdc180
|
UTSW |
4 |
45,914,803 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0276:Ccdc180
|
UTSW |
4 |
45,923,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0362:Ccdc180
|
UTSW |
4 |
45,923,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Ccdc180
|
UTSW |
4 |
45,930,197 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0468:Ccdc180
|
UTSW |
4 |
45,923,271 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0539:Ccdc180
|
UTSW |
4 |
45,922,010 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0543:Ccdc180
|
UTSW |
4 |
45,900,041 (GRCm39) |
nonsense |
probably null |
|
|
R0546:Ccdc180
|
UTSW |
4 |
45,904,597 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0612:Ccdc180
|
UTSW |
4 |
45,927,969 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0792:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1056:Ccdc180
|
UTSW |
4 |
45,916,375 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1099:Ccdc180
|
UTSW |
4 |
45,914,225 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1136:Ccdc180
|
UTSW |
4 |
45,914,589 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1263:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1331:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1522:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1819:Ccdc180
|
UTSW |
4 |
45,926,195 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R2022:Ccdc180
|
UTSW |
4 |
45,944,418 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2056:Ccdc180
|
UTSW |
4 |
45,932,477 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2219:Ccdc180
|
UTSW |
4 |
45,944,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2228:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2229:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2255:Ccdc180
|
UTSW |
4 |
45,921,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2427:Ccdc180
|
UTSW |
4 |
45,929,545 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3001:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3002:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3003:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3110:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3111:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3112:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3898:Ccdc180
|
UTSW |
4 |
45,912,799 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4022:Ccdc180
|
UTSW |
4 |
45,904,560 (GRCm39) |
nonsense |
probably null |
|
|
R4084:Ccdc180
|
UTSW |
4 |
45,950,632 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4377:Ccdc180
|
UTSW |
4 |
45,941,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4595:Ccdc180
|
UTSW |
4 |
45,945,023 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4637:Ccdc180
|
UTSW |
4 |
45,914,443 (GRCm39) |
missense |
probably benign |
|
|
R4811:Ccdc180
|
UTSW |
4 |
45,928,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Ccdc180
|
UTSW |
4 |
45,912,794 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4858:Ccdc180
|
UTSW |
4 |
45,923,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4888:Ccdc180
|
UTSW |
4 |
45,909,308 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,453 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5042:Ccdc180
|
UTSW |
4 |
45,916,255 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5119:Ccdc180
|
UTSW |
4 |
45,914,603 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5177:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5311:Ccdc180
|
UTSW |
4 |
45,917,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5333:Ccdc180
|
UTSW |
4 |
45,890,935 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5448:Ccdc180
|
UTSW |
4 |
45,920,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5510:Ccdc180
|
UTSW |
4 |
45,928,046 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6018:Ccdc180
|
UTSW |
4 |
45,926,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6108:Ccdc180
|
UTSW |
4 |
45,911,389 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6283:Ccdc180
|
UTSW |
4 |
45,902,486 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6483:Ccdc180
|
UTSW |
4 |
45,921,950 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6618:Ccdc180
|
UTSW |
4 |
45,950,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7017:Ccdc180
|
UTSW |
4 |
45,940,934 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7205:Ccdc180
|
UTSW |
4 |
45,914,588 (GRCm39) |
missense |
probably benign |
|
|
R7351:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7418:Ccdc180
|
UTSW |
4 |
45,904,616 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7492:Ccdc180
|
UTSW |
4 |
45,930,009 (GRCm39) |
splice site |
probably null |
|
|
R7573:Ccdc180
|
UTSW |
4 |
45,922,015 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7639:Ccdc180
|
UTSW |
4 |
45,928,043 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7792:Ccdc180
|
UTSW |
4 |
45,890,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7806:Ccdc180
|
UTSW |
4 |
45,912,801 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7812:Ccdc180
|
UTSW |
4 |
45,906,952 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7840:Ccdc180
|
UTSW |
4 |
45,900,461 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7842:Ccdc180
|
UTSW |
4 |
45,909,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8712:Ccdc180
|
UTSW |
4 |
45,920,842 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8818:Ccdc180
|
UTSW |
4 |
45,900,484 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8961:Ccdc180
|
UTSW |
4 |
45,929,573 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R8983:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9035:Ccdc180
|
UTSW |
4 |
45,906,922 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Ccdc180
|
UTSW |
4 |
45,949,466 (GRCm39) |
nonsense |
probably null |
|
|
R9240:Ccdc180
|
UTSW |
4 |
45,917,566 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9293:Ccdc180
|
UTSW |
4 |
45,944,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Ccdc180
|
UTSW |
4 |
45,902,447 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9346:Ccdc180
|
UTSW |
4 |
45,927,953 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9521:Ccdc180
|
UTSW |
4 |
45,916,283 (GRCm39) |
missense |
probably null |
0.50 |
|
R9653:Ccdc180
|
UTSW |
4 |
45,923,495 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9667:Ccdc180
|
UTSW |
4 |
45,920,861 (GRCm39) |
nonsense |
probably null |
|
|
X0017:Ccdc180
|
UTSW |
4 |
45,909,350 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,920,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,916,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTGAAGATGCTCTCTGCCC -3'
(R):5'- AACCTATCCTGGCAAGACCTG -3'
Sequencing Primer
(F):5'- GAAGATGCTCTCTGCCCTGCTC -3'
(R):5'- ATGGGAGCCTACACTTATGC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation