Incidental Mutation 'R7343:Dscaml1'
| ID |
570022 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dscaml1
|
| Ensembl Gene |
ENSMUSG00000032087 |
| Gene Name |
DS cell adhesion molecule like 1 |
| Synonyms |
4921507G06Rik, 4930435C18Rik |
| MMRRC Submission |
045433-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.416)
|
| Stock # |
R7343 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
45338735-45665011 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 45664214 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glycine
at position 2030
(R2030G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000034592
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000034592]
|
| AlphaFold |
Q4VA61 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000034592
AA Change: R2030G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000034592
Gene: ENSMUSG00000032087
AA Change: R2030G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
17 |
N/A |
INTRINSIC |
|
low complexity region
|
28 |
55 |
N/A |
INTRINSIC |
|
IG_like
|
96 |
168 |
1.22e0 |
SMART |
|
IG
|
189 |
277 |
1.15e-3 |
SMART |
|
IGc2
|
296 |
359 |
2.54e-14 |
SMART |
|
IGc2
|
385 |
451 |
8.12e-13 |
SMART |
|
IGc2
|
478 |
550 |
9.55e-10 |
SMART |
|
IGc2
|
575 |
640 |
9.78e-7 |
SMART |
|
IGc2
|
666 |
734 |
5.93e-6 |
SMART |
|
IGc2
|
760 |
832 |
6.75e-10 |
SMART |
|
IG
|
853 |
943 |
1e-3 |
SMART |
|
FN3
|
945 |
1029 |
6.64e-7 |
SMART |
|
FN3
|
1045 |
1133 |
9.46e-12 |
SMART |
|
FN3
|
1148 |
1234 |
3.2e-9 |
SMART |
|
FN3
|
1249 |
1332 |
3.48e-10 |
SMART |
|
IGc2
|
1363 |
1428 |
1.49e-11 |
SMART |
|
FN3
|
1442 |
1522 |
3.42e-9 |
SMART |
|
FN3
|
1537 |
1618 |
2.14e-1 |
SMART |
|
low complexity region
|
1671 |
1683 |
N/A |
INTRINSIC |
|
low complexity region
|
2018 |
2026 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2069 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation. The encoded membrane-bound protein localizes to the cell surface, where it forms aggregates that repel neuronal processes of the same cell type. [provided by RefSeq, Sep 2016]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit impaired self-avoidance in multiple cell types in the retina. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700003E16Rik |
A |
C |
6: 83,139,353 (GRCm39) |
N426T |
probably benign |
Het |
| 6430548M08Rik |
A |
G |
8: 120,872,327 (GRCm39) |
D85G |
probably benign |
Het |
| Abcb11 |
C |
T |
2: 69,130,211 (GRCm39) |
D282N |
probably damaging |
Het |
| Abcg3 |
A |
T |
5: 105,116,100 (GRCm39) |
F245I |
probably benign |
Het |
| Abhd17a |
G |
T |
10: 80,419,991 (GRCm39) |
F231L |
possibly damaging |
Het |
| Adgra1 |
A |
T |
7: 139,456,058 (GRCm39) |
D562V |
probably damaging |
Het |
| Akap7 |
C |
A |
10: 25,165,567 (GRCm39) |
|
probably benign |
Het |
| Akap9 |
A |
G |
5: 4,096,364 (GRCm39) |
D2413G |
probably damaging |
Het |
| Akr1c18 |
A |
T |
13: 4,187,236 (GRCm39) |
C193S |
probably damaging |
Het |
| Aloxe3 |
A |
T |
11: 69,023,569 (GRCm39) |
M231L |
probably benign |
Het |
| Apoh |
A |
G |
11: 108,286,674 (GRCm39) |
T33A |
probably benign |
Het |
| Atp13a5 |
T |
C |
16: 29,140,567 (GRCm39) |
N330D |
probably benign |
Het |
| C1ql3 |
T |
G |
2: 13,015,589 (GRCm39) |
M24L |
probably benign |
Het |
| Cacna1d |
T |
C |
14: 29,845,014 (GRCm39) |
N712S |
probably benign |
Het |
| Cbs |
T |
C |
17: 31,838,113 (GRCm39) |
M379V |
possibly damaging |
Het |
| Ccdc167 |
T |
C |
17: 29,924,517 (GRCm39) |
D28G |
probably damaging |
Het |
| Ccp110 |
A |
T |
7: 118,323,798 (GRCm39) |
Q679L |
probably benign |
Het |
| Ccz1 |
A |
T |
5: 143,935,000 (GRCm39) |
L310H |
probably damaging |
Het |
| Cerkl |
A |
T |
2: 79,259,104 (GRCm39) |
D44E |
probably damaging |
Het |
| Cfap221 |
T |
A |
1: 119,922,828 (GRCm39) |
E38V |
possibly damaging |
Het |
| Chia1 |
T |
A |
3: 106,039,331 (GRCm39) |
*474R |
probably null |
Het |
| Clint1 |
C |
T |
11: 45,774,590 (GRCm39) |
T32M |
probably damaging |
Het |
| Clk3 |
A |
T |
9: 57,668,239 (GRCm39) |
F227L |
probably damaging |
Het |
| Col5a3 |
C |
T |
9: 20,705,242 (GRCm39) |
|
probably null |
Het |
| Cul2 |
T |
C |
18: 3,426,873 (GRCm39) |
I501T |
probably benign |
Het |
| Dag1 |
G |
A |
9: 108,086,292 (GRCm39) |
A283V |
possibly damaging |
Het |
| Ddr2 |
A |
T |
1: 169,809,647 (GRCm39) |
W777R |
probably damaging |
Het |
| Deaf1 |
A |
T |
7: 140,902,871 (GRCm39) |
V151D |
probably damaging |
Het |
| Dido1 |
A |
T |
2: 180,316,914 (GRCm39) |
V631E |
possibly damaging |
Het |
| Dpp4 |
G |
A |
2: 62,189,245 (GRCm39) |
Q429* |
probably null |
Het |
| Dsel |
C |
T |
1: 111,789,303 (GRCm39) |
G411S |
probably damaging |
Het |
| E2f8 |
T |
A |
7: 48,517,713 (GRCm39) |
M697L |
probably damaging |
Het |
| Eef2kmt |
C |
A |
16: 5,065,299 (GRCm39) |
G303W |
probably damaging |
Het |
| Eif2ak1 |
A |
G |
5: 143,814,489 (GRCm39) |
Y182C |
probably damaging |
Het |
| Epha6 |
G |
T |
16: 59,780,793 (GRCm39) |
A636E |
probably damaging |
Het |
| Fancd2 |
G |
A |
6: 113,513,900 (GRCm39) |
V95I |
probably benign |
Het |
| Fbln5 |
A |
T |
12: 101,727,075 (GRCm39) |
C292S |
probably damaging |
Het |
| Fgfr4 |
A |
G |
13: 55,306,968 (GRCm39) |
Y219C |
probably damaging |
Het |
| Frem1 |
T |
G |
4: 82,912,359 (GRCm39) |
K670T |
probably damaging |
Het |
| Fsip2 |
A |
T |
2: 82,809,711 (GRCm39) |
H2010L |
probably benign |
Het |
| Gas2l2 |
A |
T |
11: 83,312,816 (GRCm39) |
L832* |
probably null |
Het |
| Gbe1 |
A |
G |
16: 70,157,903 (GRCm39) |
T101A |
probably benign |
Het |
| Gm5114 |
T |
A |
7: 39,058,180 (GRCm39) |
I480F |
probably damaging |
Het |
| Gm7145 |
A |
T |
1: 117,913,842 (GRCm39) |
R241S |
probably damaging |
Het |
| Gnal |
G |
A |
18: 67,268,596 (GRCm39) |
V161I |
probably benign |
Het |
| Gtpbp1 |
T |
C |
15: 79,575,243 (GRCm39) |
C46R |
probably benign |
Het |
| Gucy2c |
A |
T |
6: 136,679,746 (GRCm39) |
L971Q |
probably damaging |
Het |
| Hsp90b1 |
T |
C |
10: 86,528,047 (GRCm39) |
E740G |
probably damaging |
Het |
| Lingo2 |
G |
A |
4: 35,709,450 (GRCm39) |
L177F |
possibly damaging |
Het |
| Mfsd6l |
A |
G |
11: 68,447,874 (GRCm39) |
T242A |
possibly damaging |
Het |
| Mmadhc |
C |
T |
2: 50,181,457 (GRCm39) |
R71K |
probably damaging |
Het |
| Mrm3 |
G |
T |
11: 76,140,726 (GRCm39) |
V245L |
probably damaging |
Het |
| Nav3 |
T |
A |
10: 109,739,619 (GRCm39) |
I117F |
probably damaging |
Het |
| Noc3l |
A |
T |
19: 38,783,468 (GRCm39) |
V636D |
probably damaging |
Het |
| Nwd1 |
A |
T |
8: 73,438,410 (GRCm39) |
Q1486L |
probably damaging |
Het |
| Or10aa1 |
A |
T |
1: 173,870,419 (GRCm39) |
K301M |
probably damaging |
Het |
| Or2y10 |
A |
G |
11: 49,455,329 (GRCm39) |
T194A |
possibly damaging |
Het |
| Or3a10 |
G |
T |
11: 73,935,726 (GRCm39) |
R125S |
possibly damaging |
Het |
| Or4c11c |
T |
G |
2: 88,662,190 (GRCm39) |
I243R |
probably damaging |
Het |
| Or6c5b |
C |
G |
10: 129,245,852 (GRCm39) |
L206V |
possibly damaging |
Het |
| Pax9 |
T |
A |
12: 56,742,647 (GRCm39) |
M1K |
probably null |
Het |
| Pcdha1 |
T |
C |
18: 37,063,702 (GRCm39) |
V122A |
probably damaging |
Het |
| Pgpep1l |
A |
T |
7: 67,887,469 (GRCm39) |
S44T |
probably damaging |
Het |
| Pla2g3 |
C |
T |
11: 3,443,022 (GRCm39) |
L452F |
possibly damaging |
Het |
| Plbd2 |
G |
A |
5: 120,631,214 (GRCm39) |
R188W |
probably damaging |
Het |
| Ppp1r42 |
G |
A |
1: 10,039,082 (GRCm39) |
P346L |
probably benign |
Het |
| Prdm8 |
T |
A |
5: 98,332,375 (GRCm39) |
V92D |
probably damaging |
Het |
| Ripor2 |
C |
A |
13: 24,885,427 (GRCm39) |
S554* |
probably null |
Het |
| Rps19 |
T |
C |
7: 24,584,571 (GRCm39) |
V4A |
probably damaging |
Het |
| Rrm2b |
T |
A |
15: 37,944,817 (GRCm39) |
I159F |
probably benign |
Het |
| Rusc1 |
C |
A |
3: 88,999,057 (GRCm39) |
G242W |
probably damaging |
Het |
| Sarm1 |
A |
G |
11: 78,388,083 (GRCm39) |
S68P |
possibly damaging |
Het |
| Sctr |
G |
A |
1: 119,949,955 (GRCm39) |
R48Q |
probably benign |
Het |
| Slc22a4 |
A |
G |
11: 53,877,364 (GRCm39) |
F509S |
possibly damaging |
Het |
| Slc39a12 |
G |
A |
2: 14,456,811 (GRCm39) |
A600T |
probably damaging |
Het |
| Spta1 |
A |
T |
1: 174,050,915 (GRCm39) |
H1798L |
probably damaging |
Het |
| Sulf2 |
T |
G |
2: 165,919,536 (GRCm39) |
D804A |
possibly damaging |
Het |
| Suz12 |
A |
T |
11: 79,910,529 (GRCm39) |
E316D |
probably benign |
Het |
| Tbrg4 |
A |
G |
11: 6,570,065 (GRCm39) |
S270P |
probably benign |
Het |
| Tecta |
T |
C |
9: 42,248,628 (GRCm39) |
T1925A |
probably damaging |
Het |
| Thrap3 |
A |
T |
4: 126,072,223 (GRCm39) |
F390I |
probably damaging |
Het |
| Tpr |
C |
A |
1: 150,269,245 (GRCm39) |
A70E |
unknown |
Het |
| Trpv4 |
G |
C |
5: 114,774,520 (GRCm39) |
P188R |
probably benign |
Het |
| Txlna |
A |
C |
4: 129,525,953 (GRCm39) |
L298R |
probably damaging |
Het |
| Ubr4 |
T |
C |
4: 139,140,749 (GRCm39) |
S1223P |
probably benign |
Het |
| Ucp1 |
A |
T |
8: 84,021,881 (GRCm39) |
T238S |
probably damaging |
Het |
| Ush2a |
A |
G |
1: 188,147,943 (GRCm39) |
S957G |
probably benign |
Het |
| Usp34 |
A |
G |
11: 23,438,868 (GRCm39) |
N3496D |
|
Het |
| Vmn2r50 |
T |
C |
7: 9,784,277 (GRCm39) |
|
probably null |
Het |
| Wdr54 |
A |
G |
6: 83,131,921 (GRCm39) |
V130A |
probably benign |
Het |
| Zfp692 |
A |
T |
11: 58,202,331 (GRCm39) |
E362V |
probably damaging |
Het |
| Zfp811 |
A |
G |
17: 33,016,487 (GRCm39) |
Y518H |
probably damaging |
Het |
| Zfp994 |
A |
C |
17: 22,419,049 (GRCm39) |
C633W |
probably benign |
Het |
|
| Other mutations in Dscaml1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00418:Dscaml1
|
APN |
9 |
45,581,498 (GRCm39) |
nonsense |
probably null |
|
|
IGL00497:Dscaml1
|
APN |
9 |
45,663,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00895:Dscaml1
|
APN |
9 |
45,662,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01011:Dscaml1
|
APN |
9 |
45,594,970 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01086:Dscaml1
|
APN |
9 |
45,613,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL01125:Dscaml1
|
APN |
9 |
45,660,930 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01132:Dscaml1
|
APN |
9 |
45,663,626 (GRCm39) |
nonsense |
probably null |
|
|
IGL01356:Dscaml1
|
APN |
9 |
45,658,155 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01459:Dscaml1
|
APN |
9 |
45,653,981 (GRCm39) |
nonsense |
probably null |
|
|
IGL01552:Dscaml1
|
APN |
9 |
45,359,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02033:Dscaml1
|
APN |
9 |
45,595,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02044:Dscaml1
|
APN |
9 |
45,658,241 (GRCm39) |
nonsense |
probably null |
|
|
IGL02095:Dscaml1
|
APN |
9 |
45,359,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02166:Dscaml1
|
APN |
9 |
45,594,999 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,643,378 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,656,414 (GRCm39) |
missense |
probably benign |
|
|
IGL02340:Dscaml1
|
APN |
9 |
45,581,474 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02604:Dscaml1
|
APN |
9 |
45,655,626 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02619:Dscaml1
|
APN |
9 |
45,359,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02805:Dscaml1
|
APN |
9 |
45,359,195 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03409:Dscaml1
|
APN |
9 |
45,581,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D3080:Dscaml1
|
UTSW |
9 |
45,595,623 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL03050:Dscaml1
|
UTSW |
9 |
45,654,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Dscaml1
|
UTSW |
9 |
45,653,978 (GRCm39) |
nonsense |
probably null |
|
|
R0582:Dscaml1
|
UTSW |
9 |
45,579,562 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0629:Dscaml1
|
UTSW |
9 |
45,632,716 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0632:Dscaml1
|
UTSW |
9 |
45,643,432 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0815:Dscaml1
|
UTSW |
9 |
45,656,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1162:Dscaml1
|
UTSW |
9 |
45,663,647 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Dscaml1
|
UTSW |
9 |
45,653,521 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1474:Dscaml1
|
UTSW |
9 |
45,596,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1481:Dscaml1
|
UTSW |
9 |
45,583,941 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1533:Dscaml1
|
UTSW |
9 |
45,361,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1542:Dscaml1
|
UTSW |
9 |
45,660,738 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1572:Dscaml1
|
UTSW |
9 |
45,632,631 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1627:Dscaml1
|
UTSW |
9 |
45,664,445 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1634:Dscaml1
|
UTSW |
9 |
45,584,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Dscaml1
|
UTSW |
9 |
45,663,988 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1777:Dscaml1
|
UTSW |
9 |
45,595,054 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1812:Dscaml1
|
UTSW |
9 |
45,662,584 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1834:Dscaml1
|
UTSW |
9 |
45,594,930 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1907:Dscaml1
|
UTSW |
9 |
45,651,778 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1953:Dscaml1
|
UTSW |
9 |
45,581,522 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2056:Dscaml1
|
UTSW |
9 |
45,661,430 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2193:Dscaml1
|
UTSW |
9 |
45,596,532 (GRCm39) |
missense |
probably benign |
0.21 |
|
R2497:Dscaml1
|
UTSW |
9 |
45,656,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3768:Dscaml1
|
UTSW |
9 |
45,643,435 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3891:Dscaml1
|
UTSW |
9 |
45,628,782 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4110:Dscaml1
|
UTSW |
9 |
45,643,366 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4706:Dscaml1
|
UTSW |
9 |
45,361,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4716:Dscaml1
|
UTSW |
9 |
45,361,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4719:Dscaml1
|
UTSW |
9 |
45,583,993 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4770:Dscaml1
|
UTSW |
9 |
45,581,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Dscaml1
|
UTSW |
9 |
45,656,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5167:Dscaml1
|
UTSW |
9 |
45,628,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Dscaml1
|
UTSW |
9 |
45,361,857 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5737:Dscaml1
|
UTSW |
9 |
45,656,483 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5977:Dscaml1
|
UTSW |
9 |
45,632,596 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6073:Dscaml1
|
UTSW |
9 |
45,361,881 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6276:Dscaml1
|
UTSW |
9 |
45,579,458 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6415:Dscaml1
|
UTSW |
9 |
45,594,975 (GRCm39) |
nonsense |
probably null |
|
|
R6527:Dscaml1
|
UTSW |
9 |
45,623,482 (GRCm39) |
nonsense |
probably null |
|
|
R6582:Dscaml1
|
UTSW |
9 |
45,664,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6655:Dscaml1
|
UTSW |
9 |
45,658,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6772:Dscaml1
|
UTSW |
9 |
45,621,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6799:Dscaml1
|
UTSW |
9 |
45,361,881 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6892:Dscaml1
|
UTSW |
9 |
45,595,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6918:Dscaml1
|
UTSW |
9 |
45,341,805 (GRCm39) |
missense |
probably benign |
|
|
R6967:Dscaml1
|
UTSW |
9 |
45,585,821 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7214:Dscaml1
|
UTSW |
9 |
45,581,437 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7286:Dscaml1
|
UTSW |
9 |
45,654,044 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7315:Dscaml1
|
UTSW |
9 |
45,656,423 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7338:Dscaml1
|
UTSW |
9 |
45,585,802 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7395:Dscaml1
|
UTSW |
9 |
45,613,703 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7439:Dscaml1
|
UTSW |
9 |
45,621,624 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7484:Dscaml1
|
UTSW |
9 |
45,660,744 (GRCm39) |
splice site |
probably null |
|
|
R7545:Dscaml1
|
UTSW |
9 |
45,596,681 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7979:Dscaml1
|
UTSW |
9 |
45,595,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:Dscaml1
|
UTSW |
9 |
45,628,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8181:Dscaml1
|
UTSW |
9 |
45,658,140 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8262:Dscaml1
|
UTSW |
9 |
45,658,438 (GRCm39) |
intron |
probably benign |
|
|
R8428:Dscaml1
|
UTSW |
9 |
45,653,884 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8725:Dscaml1
|
UTSW |
9 |
45,341,759 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8727:Dscaml1
|
UTSW |
9 |
45,341,759 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Dscaml1
|
UTSW |
9 |
45,359,026 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8840:Dscaml1
|
UTSW |
9 |
45,634,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9291:Dscaml1
|
UTSW |
9 |
45,359,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9394:Dscaml1
|
UTSW |
9 |
45,661,354 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9610:Dscaml1
|
UTSW |
9 |
45,579,522 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9611:Dscaml1
|
UTSW |
9 |
45,579,522 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9653:Dscaml1
|
UTSW |
9 |
45,643,466 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9699:Dscaml1
|
UTSW |
9 |
45,654,315 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0058:Dscaml1
|
UTSW |
9 |
45,663,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dscaml1
|
UTSW |
9 |
45,584,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTACTGCAACCTGCCACTG -3'
(R):5'- CATTTCGAGTAGTGAGTCCCTGG -3'
Sequencing Primer
(F):5'- AAGTCTGAGGCCTTCTTCCGAAAG -3'
(R):5'- AGTAGTGAGTCCCTGGAGCCC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation