Incidental Mutation 'R0645:Zdbf2'
| ID |
57022 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zdbf2
|
| Ensembl Gene |
ENSMUSG00000027520 |
| Gene Name |
zinc finger, DBF-type containing 2 |
| Synonyms |
4930431J08Rik, 9330107J05Rik |
| MMRRC Submission |
038830-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.096)
|
| Stock # |
R0645 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
63312424-63353735 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 63344109 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 829
(D829E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109767
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029025]
[ENSMUST00000114132]
|
| AlphaFold |
Q5SS00 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000029025
AA Change: D829E
PolyPhen 2
Score 0.805 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000029025
Gene: ENSMUSG00000027520
AA Change: D829E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
405 |
N/A |
INTRINSIC |
|
internal_repeat_6
|
407 |
565 |
7.68e-5 |
PROSPERO |
|
internal_repeat_5
|
418 |
768 |
5.53e-5 |
PROSPERO |
|
internal_repeat_1
|
618 |
873 |
3.17e-15 |
PROSPERO |
|
internal_repeat_4
|
621 |
885 |
2.09e-6 |
PROSPERO |
|
internal_repeat_3
|
642 |
886 |
1.52e-7 |
PROSPERO |
|
internal_repeat_2
|
650 |
912 |
5.87e-11 |
PROSPERO |
|
internal_repeat_6
|
722 |
891 |
7.68e-5 |
PROSPERO |
|
low complexity region
|
965 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1061 |
1328 |
2.09e-6 |
PROSPERO |
|
internal_repeat_2
|
1215 |
1484 |
5.87e-11 |
PROSPERO |
|
internal_repeat_3
|
1287 |
1507 |
1.52e-7 |
PROSPERO |
|
internal_repeat_1
|
1307 |
1536 |
3.17e-15 |
PROSPERO |
|
internal_repeat_5
|
1388 |
1758 |
5.53e-5 |
PROSPERO |
|
low complexity region
|
1767 |
1778 |
N/A |
INTRINSIC |
|
low complexity region
|
2211 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2240 |
2399 |
N/A |
INTRINSIC |
|
low complexity region
|
2402 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2446 |
2458 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000083151
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114132
AA Change: D829E
PolyPhen 2
Score 0.805 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000109767
Gene: ENSMUSG00000027520
AA Change: D829E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
405 |
N/A |
INTRINSIC |
|
internal_repeat_6
|
407 |
565 |
7.68e-5 |
PROSPERO |
|
internal_repeat_5
|
418 |
768 |
5.53e-5 |
PROSPERO |
|
internal_repeat_1
|
618 |
873 |
3.17e-15 |
PROSPERO |
|
internal_repeat_4
|
621 |
885 |
2.09e-6 |
PROSPERO |
|
internal_repeat_3
|
642 |
886 |
1.52e-7 |
PROSPERO |
|
internal_repeat_2
|
650 |
912 |
5.87e-11 |
PROSPERO |
|
internal_repeat_6
|
722 |
891 |
7.68e-5 |
PROSPERO |
|
low complexity region
|
965 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1061 |
1328 |
2.09e-6 |
PROSPERO |
|
internal_repeat_2
|
1215 |
1484 |
5.87e-11 |
PROSPERO |
|
internal_repeat_3
|
1287 |
1507 |
1.52e-7 |
PROSPERO |
|
internal_repeat_1
|
1307 |
1536 |
3.17e-15 |
PROSPERO |
|
internal_repeat_5
|
1388 |
1758 |
5.53e-5 |
PROSPERO |
|
low complexity region
|
1767 |
1778 |
N/A |
INTRINSIC |
|
low complexity region
|
2211 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2240 |
2399 |
N/A |
INTRINSIC |
|
low complexity region
|
2402 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2446 |
2458 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1369 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.5%
|
| Validation Efficiency |
99% (94/95) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam18 |
G |
T |
8: 25,162,136 (GRCm39) |
Y46* |
probably null |
Het |
| Adam26b |
A |
C |
8: 43,973,524 (GRCm39) |
C493G |
probably damaging |
Het |
| Ak5 |
A |
T |
3: 152,359,252 (GRCm39) |
L182Q |
probably damaging |
Het |
| Akt1s1 |
T |
C |
7: 44,498,645 (GRCm39) |
|
probably benign |
Het |
| Amhr2 |
G |
T |
15: 102,354,863 (GRCm39) |
G133C |
probably damaging |
Het |
| Btbd9 |
A |
T |
17: 30,743,941 (GRCm39) |
L187Q |
probably damaging |
Het |
| Ccdc117 |
A |
T |
11: 5,484,385 (GRCm39) |
|
probably benign |
Het |
| Ccdc138 |
A |
T |
10: 58,411,542 (GRCm39) |
I637F |
probably damaging |
Het |
| Ccdc162 |
A |
G |
10: 41,462,407 (GRCm39) |
|
probably benign |
Het |
| Cdc25b |
C |
A |
2: 131,033,533 (GRCm39) |
H157Q |
probably benign |
Het |
| Cdon |
A |
G |
9: 35,388,379 (GRCm39) |
|
probably null |
Het |
| Cdt1 |
G |
A |
8: 123,298,884 (GRCm39) |
|
probably benign |
Het |
| Cep350 |
C |
T |
1: 155,816,458 (GRCm39) |
|
probably null |
Het |
| Cfb |
T |
C |
17: 35,078,992 (GRCm39) |
K831R |
probably benign |
Het |
| Cldn4 |
C |
A |
5: 134,975,645 (GRCm39) |
|
probably benign |
Het |
| Cntnap5b |
T |
C |
1: 99,999,767 (GRCm39) |
|
probably benign |
Het |
| Cyp27b1 |
T |
G |
10: 126,884,967 (GRCm39) |
S77A |
probably benign |
Het |
| Dlc1 |
T |
C |
8: 37,041,203 (GRCm39) |
D1342G |
possibly damaging |
Het |
| Dlgap4 |
A |
G |
2: 156,603,799 (GRCm39) |
H887R |
probably damaging |
Het |
| Duox2 |
A |
G |
2: 122,123,139 (GRCm39) |
I503T |
probably damaging |
Het |
| Eml4 |
T |
C |
17: 83,770,922 (GRCm39) |
|
probably benign |
Het |
| Ermap |
A |
G |
4: 119,042,888 (GRCm39) |
S212P |
probably benign |
Het |
| Esrrg |
T |
A |
1: 187,775,538 (GRCm39) |
C22S |
probably benign |
Het |
| Evx2 |
T |
A |
2: 74,488,238 (GRCm39) |
Y194F |
possibly damaging |
Het |
| Fbn2 |
T |
G |
18: 58,191,461 (GRCm39) |
D1554A |
probably damaging |
Het |
| Flrt1 |
G |
A |
19: 7,074,508 (GRCm39) |
|
probably benign |
Het |
| Fndc5 |
A |
G |
4: 129,033,630 (GRCm39) |
|
probably benign |
Het |
| Frem1 |
A |
T |
4: 82,907,403 (GRCm39) |
I837N |
probably damaging |
Het |
| Fzd10 |
G |
T |
5: 128,679,662 (GRCm39) |
A461S |
possibly damaging |
Het |
| Ganab |
T |
A |
19: 8,888,477 (GRCm39) |
Y511N |
probably damaging |
Het |
| Gbp7 |
A |
G |
3: 142,243,926 (GRCm39) |
|
probably null |
Het |
| Gm5919 |
T |
A |
9: 83,765,436 (GRCm39) |
C91S |
unknown |
Het |
| Gpr31b |
A |
T |
17: 13,271,093 (GRCm39) |
C25* |
probably null |
Het |
| Grb10 |
A |
G |
11: 11,886,755 (GRCm39) |
S505P |
probably damaging |
Het |
| Grm4 |
A |
T |
17: 27,654,183 (GRCm39) |
V542E |
probably damaging |
Het |
| Gsta5 |
T |
C |
9: 78,206,303 (GRCm39) |
I75T |
possibly damaging |
Het |
| Hivep3 |
G |
A |
4: 119,954,531 (GRCm39) |
R949H |
possibly damaging |
Het |
| Hycc1 |
C |
T |
5: 24,184,506 (GRCm39) |
G242D |
probably damaging |
Het |
| Invs |
A |
T |
4: 48,407,653 (GRCm39) |
M543L |
probably benign |
Het |
| Kcnk2 |
T |
C |
1: 188,988,927 (GRCm39) |
|
probably null |
Het |
| Kdm6b |
A |
T |
11: 69,295,844 (GRCm39) |
S808T |
unknown |
Het |
| Klhl30 |
C |
T |
1: 91,283,228 (GRCm39) |
R277W |
probably damaging |
Het |
| Lama1 |
A |
G |
17: 68,080,707 (GRCm39) |
Q1245R |
probably benign |
Het |
| Lingo3 |
G |
T |
10: 80,671,169 (GRCm39) |
H254N |
probably benign |
Het |
| Lzts1 |
A |
T |
8: 69,588,392 (GRCm39) |
H521Q |
possibly damaging |
Het |
| Map3k19 |
A |
C |
1: 127,749,919 (GRCm39) |
I1144S |
possibly damaging |
Het |
| Mast2 |
A |
G |
4: 116,165,184 (GRCm39) |
S1411P |
probably damaging |
Het |
| Mast2 |
T |
C |
4: 116,170,043 (GRCm39) |
|
probably benign |
Het |
| Mesp1 |
G |
T |
7: 79,442,328 (GRCm39) |
S225R |
possibly damaging |
Het |
| Micu1 |
A |
G |
10: 59,675,503 (GRCm39) |
T366A |
possibly damaging |
Het |
| Mideas |
G |
T |
12: 84,205,077 (GRCm39) |
N834K |
possibly damaging |
Het |
| Mknk2 |
T |
C |
10: 80,507,742 (GRCm39) |
|
probably null |
Het |
| Msh5 |
A |
G |
17: 35,258,199 (GRCm39) |
L309P |
probably damaging |
Het |
| Myo7b |
T |
C |
18: 32,127,962 (GRCm39) |
I577V |
probably benign |
Het |
| Myom2 |
T |
A |
8: 15,167,698 (GRCm39) |
D1094E |
probably damaging |
Het |
| Nedd1 |
T |
C |
10: 92,527,693 (GRCm39) |
|
probably null |
Het |
| Neu4 |
T |
C |
1: 93,950,191 (GRCm39) |
L50S |
probably damaging |
Het |
| Noa1 |
T |
C |
5: 77,457,722 (GRCm39) |
Y61C |
probably benign |
Het |
| Nr1h4 |
A |
T |
10: 89,342,390 (GRCm39) |
M30K |
probably benign |
Het |
| Nsd3 |
A |
G |
8: 26,199,096 (GRCm39) |
I1219V |
probably benign |
Het |
| Nup188 |
T |
A |
2: 30,233,478 (GRCm39) |
|
probably null |
Het |
| Or10ag2 |
T |
A |
2: 87,248,612 (GRCm39) |
Y71* |
probably null |
Het |
| Or5al5 |
A |
G |
2: 85,961,378 (GRCm39) |
S210P |
probably damaging |
Het |
| Or6c208 |
T |
A |
10: 129,224,162 (GRCm39) |
I220N |
possibly damaging |
Het |
| Or6k2 |
A |
T |
1: 173,986,920 (GRCm39) |
T194S |
probably benign |
Het |
| Pbk |
G |
A |
14: 66,051,245 (GRCm39) |
|
probably benign |
Het |
| Pcnx2 |
G |
A |
8: 126,487,459 (GRCm39) |
T1848M |
possibly damaging |
Het |
| Pdzd7 |
C |
T |
19: 45,033,914 (GRCm39) |
G57R |
possibly damaging |
Het |
| Pik3r4 |
C |
A |
9: 105,546,386 (GRCm39) |
|
probably benign |
Het |
| Plce1 |
A |
G |
19: 38,766,433 (GRCm39) |
S2153G |
probably damaging |
Het |
| Potefam1 |
C |
T |
2: 111,044,928 (GRCm39) |
|
probably null |
Het |
| Pphln1 |
G |
A |
15: 93,318,192 (GRCm39) |
V34M |
possibly damaging |
Het |
| Prrc2a |
T |
C |
17: 35,375,308 (GRCm39) |
D1114G |
probably damaging |
Het |
| Prss16 |
T |
C |
13: 22,193,546 (GRCm39) |
|
probably benign |
Het |
| Rtp3 |
T |
C |
9: 110,816,168 (GRCm39) |
K128E |
probably damaging |
Het |
| Scn3a |
T |
A |
2: 65,355,194 (GRCm39) |
I241F |
possibly damaging |
Het |
| Setd1a |
G |
A |
7: 127,386,382 (GRCm39) |
V336I |
probably damaging |
Het |
| Sfpq |
A |
G |
4: 126,916,762 (GRCm39) |
I320V |
possibly damaging |
Het |
| Skint5 |
A |
T |
4: 113,620,679 (GRCm39) |
D678E |
unknown |
Het |
| Slc12a9 |
G |
A |
5: 137,313,638 (GRCm39) |
P774S |
probably benign |
Het |
| Slc25a54 |
C |
G |
3: 109,019,481 (GRCm39) |
L362V |
possibly damaging |
Het |
| Smarcd1 |
A |
G |
15: 99,605,267 (GRCm39) |
|
probably null |
Het |
| Spata31e5 |
T |
A |
1: 28,816,011 (GRCm39) |
N674Y |
probably damaging |
Het |
| Suco |
A |
T |
1: 161,661,683 (GRCm39) |
M916K |
probably damaging |
Het |
| Tiam2 |
T |
C |
17: 3,564,973 (GRCm39) |
S1404P |
possibly damaging |
Het |
| Topors |
T |
C |
4: 40,260,333 (GRCm39) |
T984A |
unknown |
Het |
| Trabd2b |
A |
T |
4: 114,443,767 (GRCm39) |
K308M |
probably damaging |
Het |
| Trmo |
A |
T |
4: 46,377,083 (GRCm39) |
|
probably benign |
Het |
| Trpc3 |
A |
T |
3: 36,725,654 (GRCm39) |
D107E |
probably benign |
Het |
| Ugcg |
C |
T |
4: 59,207,798 (GRCm39) |
P46S |
probably benign |
Het |
| Uggt2 |
A |
C |
14: 119,295,010 (GRCm39) |
Y539D |
probably benign |
Het |
| Wwc2 |
T |
G |
8: 48,353,674 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Zdbf2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Zdbf2
|
APN |
1 |
63,345,673 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL00796:Zdbf2
|
APN |
1 |
63,346,364 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00801:Zdbf2
|
APN |
1 |
63,342,197 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02803:Zdbf2
|
APN |
1 |
63,342,236 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0143:Zdbf2
|
UTSW |
1 |
63,347,233 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0147:Zdbf2
|
UTSW |
1 |
63,343,165 (GRCm39) |
nonsense |
probably null |
|
|
R0148:Zdbf2
|
UTSW |
1 |
63,343,165 (GRCm39) |
nonsense |
probably null |
|
|
R0433:Zdbf2
|
UTSW |
1 |
63,345,302 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0502:Zdbf2
|
UTSW |
1 |
63,344,449 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0765:Zdbf2
|
UTSW |
1 |
63,344,882 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1068:Zdbf2
|
UTSW |
1 |
63,342,589 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1216:Zdbf2
|
UTSW |
1 |
63,342,161 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1235:Zdbf2
|
UTSW |
1 |
63,348,232 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1352:Zdbf2
|
UTSW |
1 |
63,342,212 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1402:Zdbf2
|
UTSW |
1 |
63,342,786 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1402:Zdbf2
|
UTSW |
1 |
63,342,786 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1435:Zdbf2
|
UTSW |
1 |
63,342,199 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1562:Zdbf2
|
UTSW |
1 |
63,342,747 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1624:Zdbf2
|
UTSW |
1 |
63,343,018 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1635:Zdbf2
|
UTSW |
1 |
63,343,493 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1644:Zdbf2
|
UTSW |
1 |
63,348,131 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1662:Zdbf2
|
UTSW |
1 |
63,343,408 (GRCm39) |
nonsense |
probably null |
|
|
R1700:Zdbf2
|
UTSW |
1 |
63,341,900 (GRCm39) |
missense |
unknown |
|
|
R1720:Zdbf2
|
UTSW |
1 |
63,342,436 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1853:Zdbf2
|
UTSW |
1 |
63,344,701 (GRCm39) |
frame shift |
probably null |
|
|
R1854:Zdbf2
|
UTSW |
1 |
63,344,701 (GRCm39) |
frame shift |
probably null |
|
|
R1973:Zdbf2
|
UTSW |
1 |
63,348,860 (GRCm39) |
missense |
unknown |
|
|
R2336:Zdbf2
|
UTSW |
1 |
63,342,623 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2428:Zdbf2
|
UTSW |
1 |
63,344,774 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3010:Zdbf2
|
UTSW |
1 |
63,342,224 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3034:Zdbf2
|
UTSW |
1 |
63,343,364 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3079:Zdbf2
|
UTSW |
1 |
63,346,636 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3196:Zdbf2
|
UTSW |
1 |
63,347,579 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3711:Zdbf2
|
UTSW |
1 |
63,347,830 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R3845:Zdbf2
|
UTSW |
1 |
63,347,483 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4093:Zdbf2
|
UTSW |
1 |
63,348,940 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4250:Zdbf2
|
UTSW |
1 |
63,342,020 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4592:Zdbf2
|
UTSW |
1 |
63,345,750 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4721:Zdbf2
|
UTSW |
1 |
63,347,951 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4779:Zdbf2
|
UTSW |
1 |
63,342,397 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4928:Zdbf2
|
UTSW |
1 |
63,347,973 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4943:Zdbf2
|
UTSW |
1 |
63,342,073 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5025:Zdbf2
|
UTSW |
1 |
63,342,809 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5095:Zdbf2
|
UTSW |
1 |
63,348,232 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5149:Zdbf2
|
UTSW |
1 |
63,344,062 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5326:Zdbf2
|
UTSW |
1 |
63,343,570 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5341:Zdbf2
|
UTSW |
1 |
63,347,092 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5511:Zdbf2
|
UTSW |
1 |
63,344,836 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5809:Zdbf2
|
UTSW |
1 |
63,345,035 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5902:Zdbf2
|
UTSW |
1 |
63,345,685 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6162:Zdbf2
|
UTSW |
1 |
63,319,977 (GRCm39) |
start gained |
probably benign |
|
|
R6245:Zdbf2
|
UTSW |
1 |
63,343,592 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Zdbf2
|
UTSW |
1 |
63,346,981 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6361:Zdbf2
|
UTSW |
1 |
63,342,480 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6489:Zdbf2
|
UTSW |
1 |
63,346,637 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6517:Zdbf2
|
UTSW |
1 |
63,344,679 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6624:Zdbf2
|
UTSW |
1 |
63,343,073 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6643:Zdbf2
|
UTSW |
1 |
63,343,667 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6786:Zdbf2
|
UTSW |
1 |
63,343,679 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6808:Zdbf2
|
UTSW |
1 |
63,347,687 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6896:Zdbf2
|
UTSW |
1 |
63,348,031 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6997:Zdbf2
|
UTSW |
1 |
63,329,925 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7011:Zdbf2
|
UTSW |
1 |
63,345,925 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7058:Zdbf2
|
UTSW |
1 |
63,346,563 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7066:Zdbf2
|
UTSW |
1 |
63,346,718 (GRCm39) |
missense |
probably benign |
|
|
R7177:Zdbf2
|
UTSW |
1 |
63,334,120 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7184:Zdbf2
|
UTSW |
1 |
63,345,664 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7273:Zdbf2
|
UTSW |
1 |
63,342,563 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7387:Zdbf2
|
UTSW |
1 |
63,343,198 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7468:Zdbf2
|
UTSW |
1 |
63,346,669 (GRCm39) |
missense |
probably benign |
|
|
R7695:Zdbf2
|
UTSW |
1 |
63,346,529 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7712:Zdbf2
|
UTSW |
1 |
63,344,530 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7735:Zdbf2
|
UTSW |
1 |
63,343,264 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7736:Zdbf2
|
UTSW |
1 |
63,347,166 (GRCm39) |
nonsense |
probably null |
|
|
R7759:Zdbf2
|
UTSW |
1 |
63,347,535 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7796:Zdbf2
|
UTSW |
1 |
63,342,583 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7908:Zdbf2
|
UTSW |
1 |
63,345,986 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7970:Zdbf2
|
UTSW |
1 |
63,343,330 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8076:Zdbf2
|
UTSW |
1 |
63,345,260 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8152:Zdbf2
|
UTSW |
1 |
63,345,572 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8195:Zdbf2
|
UTSW |
1 |
63,343,225 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8272:Zdbf2
|
UTSW |
1 |
63,345,142 (GRCm39) |
missense |
probably benign |
|
|
R8306:Zdbf2
|
UTSW |
1 |
63,343,234 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8309:Zdbf2
|
UTSW |
1 |
63,345,750 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8323:Zdbf2
|
UTSW |
1 |
63,342,073 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8400:Zdbf2
|
UTSW |
1 |
63,344,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8443:Zdbf2
|
UTSW |
1 |
63,345,166 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8460:Zdbf2
|
UTSW |
1 |
63,348,729 (GRCm39) |
small deletion |
probably benign |
|
|
R8528:Zdbf2
|
UTSW |
1 |
63,342,545 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8812:Zdbf2
|
UTSW |
1 |
63,347,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8962:Zdbf2
|
UTSW |
1 |
63,347,162 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9061:Zdbf2
|
UTSW |
1 |
63,346,296 (GRCm39) |
missense |
|
|
|
R9072:Zdbf2
|
UTSW |
1 |
63,344,923 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9232:Zdbf2
|
UTSW |
1 |
63,347,168 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9257:Zdbf2
|
UTSW |
1 |
63,345,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Zdbf2
|
UTSW |
1 |
63,343,288 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9470:Zdbf2
|
UTSW |
1 |
63,344,784 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9606:Zdbf2
|
UTSW |
1 |
63,342,536 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9621:Zdbf2
|
UTSW |
1 |
63,342,635 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
RF021:Zdbf2
|
UTSW |
1 |
63,341,811 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
X0018:Zdbf2
|
UTSW |
1 |
63,344,510 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
X0027:Zdbf2
|
UTSW |
1 |
63,347,166 (GRCm39) |
nonsense |
probably null |
|
|
X0057:Zdbf2
|
UTSW |
1 |
63,344,549 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
X0063:Zdbf2
|
UTSW |
1 |
63,344,696 (GRCm39) |
missense |
probably benign |
0.04 |
|
Z1176:Zdbf2
|
UTSW |
1 |
63,343,404 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1177:Zdbf2
|
UTSW |
1 |
63,348,362 (GRCm39) |
missense |
unknown |
|
|
Z1177:Zdbf2
|
UTSW |
1 |
63,343,245 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCTGTCAGTTACTGAGCGGTCTCTG -3'
(R):5'- AGGTTCTGTCACTGGGTGAGAAGC -3'
Sequencing Primer
(F):5'- CCTGGAAGATGAAAACTGTGTGTC -3'
(R):5'- TGGGATCTTCAGAACATCCG -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation