Incidental Mutation 'R7356:Virma'
| ID |
570943 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Virma
|
| Ensembl Gene |
ENSMUSG00000040720 |
| Gene Name |
vir like m6A methyltransferase associated |
| Synonyms |
1110037F02Rik |
| MMRRC Submission |
045442-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7356 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
11485958-11550684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 11513595 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 483
(I483N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000063188
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055372]
[ENSMUST00000059914]
[ENSMUST00000108307]
|
| AlphaFold |
A2AIV2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000055372
AA Change: I483N
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000063188
Gene: ENSMUSG00000040720
AA Change: I483N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
139 |
153 |
N/A |
INTRINSIC |
|
low complexity region
|
172 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1008 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1124 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000059914
AA Change: I483N
PolyPhen 2
Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000058078
Gene: ENSMUSG00000040720
AA Change: I483N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
139 |
153 |
N/A |
INTRINSIC |
|
low complexity region
|
172 |
198 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1008 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1124 |
N/A |
INTRINSIC |
|
low complexity region
|
1224 |
1232 |
N/A |
INTRINSIC |
|
low complexity region
|
1443 |
1458 |
N/A |
INTRINSIC |
|
low complexity region
|
1460 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1618 |
1634 |
N/A |
INTRINSIC |
|
low complexity region
|
1684 |
1697 |
N/A |
INTRINSIC |
|
low complexity region
|
1750 |
1757 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1808 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108307
AA Change: I483N
PolyPhen 2
Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000103943
Gene: ENSMUSG00000040720
AA Change: I483N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:VIR_N
|
5 |
266 |
2e-110 |
PFAM |
|
low complexity region
|
276 |
297 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1070 |
N/A |
INTRINSIC |
|
low complexity region
|
1162 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1274 |
1282 |
N/A |
INTRINSIC |
|
low complexity region
|
1493 |
1508 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1524 |
N/A |
INTRINSIC |
|
low complexity region
|
1668 |
1684 |
N/A |
INTRINSIC |
|
low complexity region
|
1734 |
1747 |
N/A |
INTRINSIC |
|
low complexity region
|
1800 |
1807 |
N/A |
INTRINSIC |
|
low complexity region
|
1846 |
1858 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acnat2 |
A |
T |
4: 49,383,507 (GRCm39) |
D15E |
probably damaging |
Het |
| Adamts16 |
G |
A |
13: 70,984,399 (GRCm39) |
T88I |
probably benign |
Het |
| Akap6 |
A |
C |
12: 52,958,647 (GRCm39) |
N801H |
probably damaging |
Het |
| Ankfn1 |
G |
T |
11: 89,325,599 (GRCm39) |
N524K |
probably damaging |
Het |
| Ap5s1 |
A |
G |
2: 131,054,582 (GRCm39) |
N131S |
probably damaging |
Het |
| Astn2 |
A |
T |
4: 66,103,503 (GRCm39) |
D303E |
unknown |
Het |
| Babam1 |
T |
C |
8: 71,852,208 (GRCm39) |
V132A |
probably benign |
Het |
| BC028528 |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
3: 95,795,448 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
CACTGGTT |
CACTGGTTCTATGGTGACTGGTT |
3: 95,795,495 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
TCTGTGGTCACTGGT |
TCTGTGGTCACTGGTCCTGTGGTCACTGGT |
3: 95,795,487 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
GGTCACTGGTTCTGT |
GGTCACTGGTTCTGTAGTCACTGGTTCTGT |
3: 95,795,477 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
GTTCTGTGGTCACTGGTTCTGTGGTCACTG |
GTTCTGTGGTCACTGCTTCTGTGGTCACTGGTTCTGTGGTCACTG |
3: 95,795,470 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
TGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCAC |
TGGTTCTGTGGTCACGGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCAC |
3: 95,795,453 (GRCm39) |
|
probably benign |
Het |
| Cnst |
C |
T |
1: 179,434,095 (GRCm39) |
P304S |
probably benign |
Het |
| Cog4 |
A |
T |
8: 111,576,498 (GRCm39) |
|
probably null |
Het |
| Cyp2j13 |
A |
T |
4: 95,965,655 (GRCm39) |
H17Q |
probably benign |
Het |
| Dock6 |
G |
A |
9: 21,721,195 (GRCm39) |
T1662I |
probably damaging |
Het |
| Dysf |
T |
C |
6: 84,044,443 (GRCm39) |
F270S |
probably damaging |
Het |
| Erbb4 |
A |
G |
1: 68,378,514 (GRCm39) |
|
probably null |
Het |
| Fam120b |
A |
T |
17: 15,627,958 (GRCm39) |
Q550L |
probably benign |
Het |
| Fam83b |
A |
T |
9: 76,400,135 (GRCm39) |
F323I |
probably benign |
Het |
| Far1 |
T |
A |
7: 113,167,349 (GRCm39) |
I478N |
possibly damaging |
Het |
| Gdpd5 |
T |
A |
7: 99,108,085 (GRCm39) |
I554N |
probably damaging |
Het |
| Glrx3 |
T |
C |
7: 137,054,453 (GRCm39) |
S79P |
probably damaging |
Het |
| Hltf |
T |
C |
3: 20,163,534 (GRCm39) |
I888T |
probably damaging |
Het |
| Hpx |
A |
G |
7: 105,240,917 (GRCm39) |
V452A |
probably damaging |
Het |
| Itk |
T |
G |
11: 46,258,659 (GRCm39) |
Q81P |
possibly damaging |
Het |
| Kdm6b |
G |
A |
11: 69,292,991 (GRCm39) |
Q1262* |
probably null |
Het |
| Lpcat2 |
T |
C |
8: 93,591,611 (GRCm39) |
V85A |
probably benign |
Het |
| Lrrk2 |
A |
T |
15: 91,622,947 (GRCm39) |
H1039L |
probably benign |
Het |
| Mapk3 |
T |
C |
7: 126,360,087 (GRCm39) |
|
probably null |
Het |
| Masp1 |
A |
T |
16: 23,288,993 (GRCm39) |
N602K |
possibly damaging |
Het |
| Myo7a |
T |
A |
7: 97,751,890 (GRCm39) |
Q40L |
probably benign |
Het |
| Nek1 |
A |
T |
8: 61,573,994 (GRCm39) |
M1081L |
probably benign |
Het |
| Nes |
T |
C |
3: 87,885,058 (GRCm39) |
S1106P |
possibly damaging |
Het |
| Nkpd1 |
A |
T |
7: 19,257,699 (GRCm39) |
I493F |
probably damaging |
Het |
| Npsr1 |
C |
G |
9: 24,009,557 (GRCm39) |
S21C |
probably benign |
Het |
| Oog1 |
G |
A |
12: 87,653,047 (GRCm39) |
|
probably null |
Het |
| Or11g1 |
G |
A |
14: 50,651,159 (GRCm39) |
V53M |
probably damaging |
Het |
| Or5g24-ps1 |
G |
A |
2: 85,463,782 (GRCm39) |
R3K |
probably benign |
Het |
| Or5k8 |
A |
T |
16: 58,644,718 (GRCm39) |
M118K |
probably damaging |
Het |
| Osbpl9 |
G |
T |
4: 108,925,677 (GRCm39) |
Y340* |
probably null |
Het |
| Pcyox1l |
A |
T |
18: 61,840,621 (GRCm39) |
L11Q |
probably null |
Het |
| Pdxdc1 |
G |
A |
16: 13,677,867 (GRCm39) |
R255C |
probably damaging |
Het |
| Pgap1 |
A |
G |
1: 54,569,293 (GRCm39) |
S358P |
probably benign |
Het |
| Pgm2l1 |
A |
G |
7: 99,917,326 (GRCm39) |
Y481C |
possibly damaging |
Het |
| Plekhf1 |
T |
C |
7: 37,921,545 (GRCm39) |
T8A |
possibly damaging |
Het |
| Plg |
G |
T |
17: 12,629,798 (GRCm39) |
G611C |
probably damaging |
Het |
| Prf1 |
A |
C |
10: 61,139,059 (GRCm39) |
D339A |
possibly damaging |
Het |
| Prph |
A |
G |
15: 98,954,807 (GRCm39) |
Y291C |
probably damaging |
Het |
| Rasal1 |
A |
G |
5: 120,792,890 (GRCm39) |
S48G |
possibly damaging |
Het |
| Rigi |
A |
G |
4: 40,226,600 (GRCm39) |
S231P |
probably benign |
Het |
| Ripk4 |
T |
A |
16: 97,544,349 (GRCm39) |
Q766L |
probably damaging |
Het |
| Scaf1 |
T |
C |
7: 44,657,208 (GRCm39) |
D557G |
unknown |
Het |
| Scaper |
A |
T |
9: 55,799,495 (GRCm39) |
M190K |
unknown |
Het |
| Scn8a |
A |
T |
15: 100,855,460 (GRCm39) |
I202F |
probably damaging |
Het |
| Siglecf |
A |
G |
7: 43,005,855 (GRCm39) |
I505V |
probably benign |
Het |
| Sirpb1c |
A |
G |
3: 15,886,297 (GRCm39) |
S360P |
probably benign |
Het |
| Sla2 |
C |
A |
2: 156,720,623 (GRCm39) |
|
probably null |
Het |
| Slc11a1 |
G |
T |
1: 74,424,648 (GRCm39) |
V544L |
probably benign |
Het |
| Slco1a5 |
T |
A |
6: 142,180,458 (GRCm39) |
K648I |
probably benign |
Het |
| Sorcs1 |
T |
A |
19: 50,163,595 (GRCm39) |
I1020F |
possibly damaging |
Het |
| Spen |
C |
A |
4: 141,199,235 (GRCm39) |
E3131* |
probably null |
Het |
| Sult2a7 |
A |
T |
7: 14,211,031 (GRCm39) |
W162R |
probably damaging |
Het |
| Sult3a1 |
G |
A |
10: 33,742,579 (GRCm39) |
E69K |
probably benign |
Het |
| Tcof1 |
G |
T |
18: 60,951,166 (GRCm39) |
D1119E |
unknown |
Het |
| Tom1l2 |
A |
T |
11: 60,139,853 (GRCm39) |
I272K |
probably damaging |
Het |
| Tspan5 |
C |
T |
3: 138,448,193 (GRCm39) |
|
probably benign |
Het |
| Ttn |
A |
G |
2: 76,698,244 (GRCm39) |
L186P |
|
Het |
| Uap1l1 |
T |
C |
2: 25,251,696 (GRCm39) |
E496G |
possibly damaging |
Het |
| Ube2v1 |
A |
T |
2: 167,451,115 (GRCm39) |
I117N |
possibly damaging |
Het |
| Usp42 |
A |
G |
5: 143,702,842 (GRCm39) |
V593A |
possibly damaging |
Het |
| Vwde |
T |
A |
6: 13,192,641 (GRCm39) |
I421F |
probably damaging |
Het |
| Zfp345 |
G |
A |
2: 150,314,209 (GRCm39) |
H443Y |
probably damaging |
Het |
| Zfp760 |
A |
G |
17: 21,941,601 (GRCm39) |
T259A |
probably benign |
Het |
| Zfp941 |
T |
C |
7: 140,392,028 (GRCm39) |
I444V |
possibly damaging |
Het |
| Zfyve9 |
A |
C |
4: 108,576,212 (GRCm39) |
S290A |
probably benign |
Het |
|
| Other mutations in Virma |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00428:Virma
|
APN |
4 |
11,519,424 (GRCm39) |
splice site |
probably benign |
|
|
IGL00477:Virma
|
APN |
4 |
11,519,006 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01293:Virma
|
APN |
4 |
11,521,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Virma
|
APN |
4 |
11,518,929 (GRCm39) |
nonsense |
probably null |
|
|
IGL01531:Virma
|
APN |
4 |
11,528,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01672:Virma
|
APN |
4 |
11,527,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01724:Virma
|
APN |
4 |
11,528,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01747:Virma
|
APN |
4 |
11,526,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01776:Virma
|
APN |
4 |
11,527,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02064:Virma
|
APN |
4 |
11,513,163 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02243:Virma
|
APN |
4 |
11,546,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02244:Virma
|
APN |
4 |
11,546,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02445:Virma
|
APN |
4 |
11,527,029 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02546:Virma
|
APN |
4 |
11,494,804 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02807:Virma
|
APN |
4 |
11,507,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL02967:Virma
|
APN |
4 |
11,514,096 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03211:Virma
|
APN |
4 |
11,548,770 (GRCm39) |
nonsense |
probably null |
|
|
IGL03242:Virma
|
APN |
4 |
11,527,669 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL03256:Virma
|
APN |
4 |
11,542,207 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Virma
|
APN |
4 |
11,518,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03346:Virma
|
APN |
4 |
11,518,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4802001:Virma
|
UTSW |
4 |
11,546,008 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0142:Virma
|
UTSW |
4 |
11,548,783 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0355:Virma
|
UTSW |
4 |
11,528,626 (GRCm39) |
nonsense |
probably null |
|
|
R0522:Virma
|
UTSW |
4 |
11,519,416 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0600:Virma
|
UTSW |
4 |
11,498,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1435:Virma
|
UTSW |
4 |
11,528,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1489:Virma
|
UTSW |
4 |
11,521,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1568:Virma
|
UTSW |
4 |
11,528,776 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Virma
|
UTSW |
4 |
11,544,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1655:Virma
|
UTSW |
4 |
11,494,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1695:Virma
|
UTSW |
4 |
11,494,814 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1835:Virma
|
UTSW |
4 |
11,540,511 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1951:Virma
|
UTSW |
4 |
11,513,907 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1991:Virma
|
UTSW |
4 |
11,519,242 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2145:Virma
|
UTSW |
4 |
11,548,726 (GRCm39) |
splice site |
probably benign |
|
|
R2172:Virma
|
UTSW |
4 |
11,527,843 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2217:Virma
|
UTSW |
4 |
11,544,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2218:Virma
|
UTSW |
4 |
11,544,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2248:Virma
|
UTSW |
4 |
11,518,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2342:Virma
|
UTSW |
4 |
11,501,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3424:Virma
|
UTSW |
4 |
11,513,177 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Virma
|
UTSW |
4 |
11,513,901 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4449:Virma
|
UTSW |
4 |
11,498,828 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4660:Virma
|
UTSW |
4 |
11,513,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4698:Virma
|
UTSW |
4 |
11,528,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4878:Virma
|
UTSW |
4 |
11,544,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4937:Virma
|
UTSW |
4 |
11,521,147 (GRCm39) |
nonsense |
probably null |
|
|
R5031:Virma
|
UTSW |
4 |
11,542,116 (GRCm39) |
nonsense |
probably null |
|
|
R5040:Virma
|
UTSW |
4 |
11,528,746 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5061:Virma
|
UTSW |
4 |
11,494,840 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5091:Virma
|
UTSW |
4 |
11,519,392 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5137:Virma
|
UTSW |
4 |
11,546,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5262:Virma
|
UTSW |
4 |
11,539,926 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5297:Virma
|
UTSW |
4 |
11,494,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5730:Virma
|
UTSW |
4 |
11,542,154 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5818:Virma
|
UTSW |
4 |
11,513,319 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5835:Virma
|
UTSW |
4 |
11,514,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6125:Virma
|
UTSW |
4 |
11,521,172 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6197:Virma
|
UTSW |
4 |
11,505,498 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6222:Virma
|
UTSW |
4 |
11,527,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6793:Virma
|
UTSW |
4 |
11,539,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7028:Virma
|
UTSW |
4 |
11,519,249 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7383:Virma
|
UTSW |
4 |
11,514,026 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7391:Virma
|
UTSW |
4 |
11,508,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7425:Virma
|
UTSW |
4 |
11,546,211 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7556:Virma
|
UTSW |
4 |
11,518,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7715:Virma
|
UTSW |
4 |
11,513,016 (GRCm39) |
splice site |
probably null |
|
|
R7715:Virma
|
UTSW |
4 |
11,549,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7986:Virma
|
UTSW |
4 |
11,540,023 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7990:Virma
|
UTSW |
4 |
11,513,983 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8048:Virma
|
UTSW |
4 |
11,539,918 (GRCm39) |
nonsense |
probably null |
|
|
R8050:Virma
|
UTSW |
4 |
11,528,643 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8165:Virma
|
UTSW |
4 |
11,542,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8412:Virma
|
UTSW |
4 |
11,521,261 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8544:Virma
|
UTSW |
4 |
11,516,949 (GRCm39) |
missense |
probably benign |
|
|
R8551:Virma
|
UTSW |
4 |
11,513,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8699:Virma
|
UTSW |
4 |
11,528,678 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8739:Virma
|
UTSW |
4 |
11,540,643 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8950:Virma
|
UTSW |
4 |
11,519,047 (GRCm39) |
nonsense |
probably null |
|
|
R9015:Virma
|
UTSW |
4 |
11,540,494 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9038:Virma
|
UTSW |
4 |
11,526,922 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9115:Virma
|
UTSW |
4 |
11,498,744 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9294:Virma
|
UTSW |
4 |
11,513,507 (GRCm39) |
nonsense |
probably null |
|
|
R9404:Virma
|
UTSW |
4 |
11,513,626 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9477:Virma
|
UTSW |
4 |
11,528,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9532:Virma
|
UTSW |
4 |
11,507,078 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9649:Virma
|
UTSW |
4 |
11,486,045 (GRCm39) |
start codon destroyed |
probably null |
0.08 |
|
R9657:Virma
|
UTSW |
4 |
11,544,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9780:Virma
|
UTSW |
4 |
11,513,442 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R9800:Virma
|
UTSW |
4 |
11,546,007 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0020:Virma
|
UTSW |
4 |
11,486,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACGGCTCTAGAAGAAATTCCAAG -3'
(R):5'- CCCTCACAGTCTGATCCAGAAG -3'
Sequencing Primer
(F):5'- AGCTATTTGCAATTGAAAAACACAG -3'
(R):5'- CAGTCTGATCCAGAAGTATGAGTTCC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation