Mutagenetix > Incidental Mutation

Incidental Mutation 'R7381:Vwa8'

572757

Institutional Source

Beutler Lab

Gene Symbol

Vwa8

Ensembl Gene

ENSMUSG00000058997

Gene Name

von Willebrand factor A domain containing 8

Synonyms

1300010F03Rik, 4932416F07Rik

MMRRC Submission

045463-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7381 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

79086492-79439750 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 79333125 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1293 (T1293A)

Ref Sequence

ENSEMBL: ENSMUSP00000048925 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000040990]

AlphaFold

Q8CC88

Predicted Effect

probably benign
Transcript: ENSMUST00000040990
AA Change: T1293A

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)

SMART Domains

Protein: ENSMUSP00000048925
Gene: ENSMUSG00000058997
AA Change: T1293A

Domain	Start	End	E-Value	Type
low complexity region	5	15	N/A	INTRINSIC
low complexity region	20	33	N/A	INTRINSIC
Pfam:AAA_5	104	260	6.3e-44	PFAM
AAA	438	613	4.69e-2	SMART
AAA	772	904	1.26e-1	SMART
low complexity region	1213	1221	N/A	INTRINSIC
low complexity region	1565	1586	N/A	INTRINSIC
VWA	1712	1901	2.71e-10	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.2%

Validation Efficiency

98% (88/90)

Allele List at MGI

Other mutations in this stock

Total: 93 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930550C14Rik	T	C	9: 53,323,122 (GRCm39)	Y53H	probably damaging	Het
Abca8a	A	T	11: 109,920,913 (GRCm39)		probably null	Het
Acads	C	A	5: 115,249,057 (GRCm39)	Q365H	probably damaging	Het
Acsm3	A	G	7: 119,380,049 (GRCm39)	D462G	probably damaging	Het
Adam39	T	A	8: 41,279,000 (GRCm39)	C464S	probably damaging	Het
Adgra3	A	G	5: 50,216,116 (GRCm39)	M1T	probably null	Het
AI182371	T	C	2: 34,975,371 (GRCm39)	Y276C	probably damaging	Het
Ank2	T	A	3: 126,730,277 (GRCm39)	H719L	possibly damaging	Het
Ano7	G	A	1: 93,323,057 (GRCm39)	V466I	probably benign	Het
Art5	A	G	7: 101,747,377 (GRCm39)	L134P	probably damaging	Het
Atcay	A	G	10: 81,046,431 (GRCm39)	Y298H	possibly damaging	Het
Atp1a4	A	T	1: 172,067,682 (GRCm39)	F527Y	possibly damaging	Het
Bpifb2	A	T	2: 153,734,268 (GRCm39)	M428L	probably benign	Het
Brinp2	A	C	1: 158,073,913 (GRCm39)	V736G	probably benign	Het
Cdc5l	C	T	17: 45,722,849 (GRCm39)	A437T	probably benign	Het
Cdx2	G	A	5: 147,243,440 (GRCm39)	P118L	possibly damaging	Het
Chpt1	G	A	10: 88,311,193 (GRCm39)		probably null	Het
Creb3l2	T	A	6: 37,312,783 (GRCm39)	E417V	probably damaging	Het
Csnk2a1	A	G	2: 152,100,614 (GRCm39)	T129A	probably benign	Het
Dennd6b	A	T	15: 89,070,376 (GRCm39)	L431Q	possibly damaging	Het
Dgkz	C	T	2: 91,775,180 (GRCm39)	A260T	probably benign	Het
Dhx34	T	A	7: 15,949,373 (GRCm39)	T352S	probably benign	Het
Elp4	C	T	2: 105,622,652 (GRCm39)	R349Q	not run	Het
Emsy	A	C	7: 98,240,010 (GRCm39)	F1228V	probably damaging	Het
Eps8l1	T	A	7: 4,473,437 (GRCm39)		probably null	Het
Faf1	T	A	4: 109,719,134 (GRCm39)	D413E	probably damaging	Het
Fat3	T	C	9: 16,158,283 (GRCm39)	Y1109C	probably damaging	Het
Fbp1	T	C	13: 63,012,867 (GRCm39)	K314E	probably benign	Het
Fbxl20	A	G	11: 97,981,614 (GRCm39)	V358A	probably benign	Het
Fbxo34	C	G	14: 47,767,992 (GRCm39)	R502G	probably benign	Het
Fxr2	G	A	11: 69,532,875 (GRCm39)	C151Y	possibly damaging	Het
Garin5b	C	A	7: 4,760,681 (GRCm39)	R677L		Het
Gja8	T	C	3: 96,827,338 (GRCm39)	D108G	probably benign	Het
Gm10722	C	A	9: 3,001,235 (GRCm39)	L104I	probably benign	Het
Grsf1	A	G	5: 88,813,666 (GRCm39)	V361A	probably benign	Het
Gsap	T	A	5: 21,431,785 (GRCm39)	I228N	probably damaging	Het
Hagh	T	C	17: 25,075,686 (GRCm39)	I131T	probably damaging	Het
Heca	A	T	10: 17,791,272 (GRCm39)	Y261*	probably null	Het
Hipk3	A	G	2: 104,269,696 (GRCm39)	F498L	probably damaging	Het
Hps4	T	A	5: 112,523,324 (GRCm39)	I614N	possibly damaging	Het
Icam1	T	C	9: 20,938,886 (GRCm39)	S450P	probably benign	Het
Il22	G	A	10: 118,041,069 (GRCm39)	M58I	possibly damaging	Het
Khdrbs2	T	A	1: 32,372,883 (GRCm39)	S186T	not run	Het
Kif16b	A	G	2: 142,699,343 (GRCm39)	F79S	probably damaging	Het
Kntc1	C	A	5: 123,948,971 (GRCm39)	F1905L	probably benign	Het
Liat1	A	T	11: 75,893,833 (GRCm39)	D70V	probably damaging	Het
Lrp1b	C	T	2: 40,692,929 (GRCm39)	G3423D		Het
Lrp5	G	T	19: 3,643,588 (GRCm39)	Q1346K	probably benign	Het
Map3k21	A	C	8: 126,671,717 (GRCm39)	T1002P	possibly damaging	Het
Mdga2	G	T	12: 66,615,670 (GRCm39)	R646S	probably benign	Het
Mex3b	G	T	7: 82,518,073 (GRCm39)	M129I	possibly damaging	Het
Mfsd10	G	T	5: 34,793,770 (GRCm39)	N85K	probably damaging	Het
Mios	A	G	6: 8,216,064 (GRCm39)	D420G	probably damaging	Het
Mogs	C	A	6: 83,092,613 (GRCm39)	P18T	unknown	Het
Mrgpre	A	G	7: 143,335,150 (GRCm39)	C118R	probably damaging	Het
Muc4	A	T	16: 32,601,285 (GRCm39)	H1321L		Het
Nkapl	T	C	13: 21,651,759 (GRCm39)	K285E	probably damaging	Het
Nphp4	C	T	4: 152,583,460 (GRCm39)	P200S	possibly damaging	Het
Piezo1	A	G	8: 123,228,397 (GRCm39)	F297L		Het
Pkhd1	T	G	1: 20,271,197 (GRCm39)	S3119R	probably damaging	Het
Pla2g15	G	A	8: 106,889,576 (GRCm39)	V283I	probably benign	Het
Ppp1r13l	T	A	7: 19,102,786 (GRCm39)		probably null	Het
Prex1	A	G	2: 166,429,047 (GRCm39)	Y849H	probably damaging	Het
Psg27	C	A	7: 18,301,008 (GRCm39)	W15L	probably benign	Het
Ptar1	A	T	19: 23,686,334 (GRCm39)		probably null	Het
Ptpn6	G	A	6: 124,705,135 (GRCm39)	R264C	probably damaging	Het
Ptprb	A	G	10: 116,177,038 (GRCm39)	I988V	probably benign	Het
Ptpro	G	A	6: 137,376,559 (GRCm39)	V680I	possibly damaging	Het
Rnf170	C	T	8: 26,613,876 (GRCm39)	P28S	probably benign	Het
Rnpepl1	A	G	1: 92,846,917 (GRCm39)	S580G	possibly damaging	Het
Rtel1	C	T	2: 180,972,608 (GRCm39)	R29*	probably null	Het
Rtkn	T	C	6: 83,128,726 (GRCm39)	L26P	probably damaging	Het
Sdk2	A	C	11: 113,729,315 (GRCm39)	S1087R	probably damaging	Het
Sema7a	C	T	9: 57,860,852 (GRCm39)	P71L	probably benign	Het
Sgpp1	C	T	12: 75,763,038 (GRCm39)	C381Y	probably damaging	Het
Sis	A	T	3: 72,820,625 (GRCm39)		probably null	Het
Slc24a5	A	C	2: 124,910,869 (GRCm39)	D100A	probably benign	Het
Slc25a23	A	T	17: 57,360,587 (GRCm39)	I251K	probably damaging	Het
Slc6a5	T	A	7: 49,579,804 (GRCm39)	L394H	probably damaging	Het
Slc7a4	A	T	16: 17,392,920 (GRCm39)	M293K	probably damaging	Het
Syne2	T	A	12: 75,973,263 (GRCm39)	S1089T	probably benign	Het
Tanc1	A	T	2: 59,615,670 (GRCm39)	T226S	probably damaging	Het
Tdrd6	T	C	17: 43,936,984 (GRCm39)	T1355A	probably benign	Het
Tmem101	A	G	11: 102,044,176 (GRCm39)	M237T	possibly damaging	Het
Ttn	G	A	2: 76,749,359 (GRCm39)	H3897Y	possibly damaging	Het
Tubb4a	C	T	17: 57,387,698 (GRCm39)	V443M	unknown	Het
Ucp2	G	A	7: 100,147,576 (GRCm39)	R185H	possibly damaging	Het
Vmn1r116	G	T	7: 20,606,436 (GRCm39)	E86*	probably null	Het
Vmn2r37	T	C	7: 9,213,032 (GRCm39)	E530G	probably benign	Het
Zfc3h1	T	A	10: 115,260,535 (GRCm39)	Y1711N	probably benign	Het
Zfp873	A	T	10: 81,896,805 (GRCm39)	E512V	probably damaging	Het
Zfyve16	T	A	13: 92,657,654 (GRCm39)	K752N	probably damaging	Het
Zhx1	T	C	15: 57,916,561 (GRCm39)	N562D	possibly damaging	Het

Other mutations in Vwa8

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00589:Vwa8	APN	14	79,275,635 (GRCm39)	missense	probably damaging	1.00
IGL01087:Vwa8	APN	14	79,172,669 (GRCm39)	missense	probably benign	0.16
IGL01137:Vwa8	APN	14	79,341,087 (GRCm39)	missense	probably damaging	1.00
IGL01359:Vwa8	APN	14	79,302,353 (GRCm39)	nonsense	probably null
IGL01449:Vwa8	APN	14	79,420,428 (GRCm39)	nonsense	probably null
IGL01604:Vwa8	APN	14	79,418,244 (GRCm39)	missense	possibly damaging	0.82
IGL01636:Vwa8	APN	14	79,435,794 (GRCm39)	missense	possibly damaging	0.68
IGL01815:Vwa8	APN	14	79,435,717 (GRCm39)	missense	possibly damaging	0.92
IGL02024:Vwa8	APN	14	79,331,724 (GRCm39)	missense	possibly damaging	0.91
IGL02033:Vwa8	APN	14	79,221,649 (GRCm39)	missense	possibly damaging	0.89
IGL02154:Vwa8	APN	14	79,086,733 (GRCm39)	missense	possibly damaging	0.53
IGL02286:Vwa8	APN	14	79,184,713 (GRCm39)	critical splice donor site	probably null
IGL02393:Vwa8	APN	14	79,420,417 (GRCm39)	missense	probably damaging	1.00
IGL02430:Vwa8	APN	14	79,172,085 (GRCm39)	critical splice donor site	probably null
IGL02476:Vwa8	APN	14	79,162,781 (GRCm39)	missense	possibly damaging	0.62
IGL02612:Vwa8	APN	14	79,420,552 (GRCm39)	missense	probably benign	0.01
IGL02678:Vwa8	APN	14	79,221,640 (GRCm39)	missense	probably damaging	0.99
IGL02797:Vwa8	APN	14	79,162,702 (GRCm39)	missense	probably benign	0.29
IGL02806:Vwa8	APN	14	79,394,528 (GRCm39)	missense	probably benign	0.35
IGL02811:Vwa8	APN	14	79,231,899 (GRCm39)	missense	probably benign	0.21
IGL02892:Vwa8	APN	14	79,341,140 (GRCm39)	splice site	probably benign
IGL03024:Vwa8	APN	14	79,232,538 (GRCm39)	missense	probably benign	0.03
IGL03075:Vwa8	APN	14	79,171,196 (GRCm39)	missense	probably damaging	0.99
IGL03090:Vwa8	APN	14	79,172,041 (GRCm39)	missense	possibly damaging	0.92
IGL03124:Vwa8	APN	14	79,296,255 (GRCm39)	splice site	probably benign
IGL03181:Vwa8	APN	14	79,246,690 (GRCm39)	missense	probably benign	0.01
IGL03296:Vwa8	APN	14	79,420,540 (GRCm39)	missense	probably damaging	0.98
IGL03376:Vwa8	APN	14	79,420,574 (GRCm39)	splice site	probably null
R6812_Vwa8_870	UTSW	14	79,434,859 (GRCm39)	missense	probably damaging	0.99
IGL03052:Vwa8	UTSW	14	79,302,361 (GRCm39)	missense	probably benign	0.02
PIT4468001:Vwa8	UTSW	14	79,420,501 (GRCm39)	missense	probably damaging	1.00
R0049:Vwa8	UTSW	14	79,331,179 (GRCm39)	missense	probably benign	0.21
R0063:Vwa8	UTSW	14	79,401,656 (GRCm39)	splice site	probably benign
R0063:Vwa8	UTSW	14	79,401,656 (GRCm39)	splice site	probably benign
R0081:Vwa8	UTSW	14	79,320,222 (GRCm39)	missense	probably benign	0.02
R0305:Vwa8	UTSW	14	79,246,713 (GRCm39)	missense	probably damaging	1.00
R0433:Vwa8	UTSW	14	79,300,116 (GRCm39)	missense	probably damaging	1.00
R0514:Vwa8	UTSW	14	79,184,629 (GRCm39)	missense	probably benign
R0602:Vwa8	UTSW	14	79,258,060 (GRCm39)	missense	probably benign	0.00
R0615:Vwa8	UTSW	14	79,145,590 (GRCm39)	missense	probably benign
R0791:Vwa8	UTSW	14	79,232,016 (GRCm39)	splice site	probably benign
R1028:Vwa8	UTSW	14	79,145,670 (GRCm39)	missense	probably damaging	1.00
R1037:Vwa8	UTSW	14	79,324,094 (GRCm39)	nonsense	probably null
R1404:Vwa8	UTSW	14	79,263,471 (GRCm39)	missense	probably damaging	1.00
R1404:Vwa8	UTSW	14	79,263,471 (GRCm39)	missense	probably damaging	1.00
R1412:Vwa8	UTSW	14	79,145,670 (GRCm39)	missense	probably damaging	1.00
R1421:Vwa8	UTSW	14	79,145,670 (GRCm39)	missense	probably damaging	1.00
R1467:Vwa8	UTSW	14	79,341,134 (GRCm39)	nonsense	probably null
R1467:Vwa8	UTSW	14	79,341,134 (GRCm39)	nonsense	probably null
R1539:Vwa8	UTSW	14	79,300,002 (GRCm39)	missense	probably benign	0.00
R1556:Vwa8	UTSW	14	79,324,121 (GRCm39)	missense	probably benign
R1589:Vwa8	UTSW	14	79,145,670 (GRCm39)	missense	probably damaging	1.00
R1590:Vwa8	UTSW	14	79,145,670 (GRCm39)	missense	probably damaging	1.00
R1591:Vwa8	UTSW	14	79,145,670 (GRCm39)	missense	probably damaging	1.00
R1645:Vwa8	UTSW	14	79,420,427 (GRCm39)	missense	probably damaging	1.00
R1673:Vwa8	UTSW	14	79,145,670 (GRCm39)	missense	probably damaging	1.00
R1688:Vwa8	UTSW	14	79,438,543 (GRCm39)	missense	possibly damaging	0.72
R1764:Vwa8	UTSW	14	79,145,635 (GRCm39)	missense	probably damaging	1.00
R1830:Vwa8	UTSW	14	79,318,576 (GRCm39)	missense	probably benign	0.04
R1926:Vwa8	UTSW	14	79,258,075 (GRCm39)	missense	probably benign	0.00
R1959:Vwa8	UTSW	14	79,219,800 (GRCm39)	missense	possibly damaging	0.95
R1971:Vwa8	UTSW	14	79,162,694 (GRCm39)	splice site	probably benign
R2078:Vwa8	UTSW	14	79,145,597 (GRCm39)	missense	probably damaging	1.00
R2103:Vwa8	UTSW	14	79,145,670 (GRCm39)	missense	probably damaging	1.00
R2230:Vwa8	UTSW	14	79,329,843 (GRCm39)	critical splice donor site	probably null
R2281:Vwa8	UTSW	14	79,302,436 (GRCm39)	missense	possibly damaging	0.91
R2313:Vwa8	UTSW	14	79,149,658 (GRCm39)	missense	probably damaging	0.98
R2847:Vwa8	UTSW	14	79,184,582 (GRCm39)	missense	probably benign	0.00
R2848:Vwa8	UTSW	14	79,184,582 (GRCm39)	missense	probably benign	0.00
R2894:Vwa8	UTSW	14	79,275,578 (GRCm39)	missense	probably damaging	1.00
R2991:Vwa8	UTSW	14	79,232,589 (GRCm39)	missense	probably benign	0.00
R3077:Vwa8	UTSW	14	79,335,782 (GRCm39)	missense	probably benign	0.03
R3405:Vwa8	UTSW	14	79,401,660 (GRCm39)	splice site	probably benign
R3406:Vwa8	UTSW	14	79,401,660 (GRCm39)	splice site	probably benign
R3708:Vwa8	UTSW	14	79,300,136 (GRCm39)	splice site	probably benign
R3779:Vwa8	UTSW	14	79,339,762 (GRCm39)	splice site	probably benign
R3799:Vwa8	UTSW	14	79,302,336 (GRCm39)	missense	probably damaging	0.99
R4230:Vwa8	UTSW	14	79,320,292 (GRCm39)	missense	probably benign	0.00
R4425:Vwa8	UTSW	14	79,320,246 (GRCm39)	missense	probably benign	0.00
R4478:Vwa8	UTSW	14	79,106,241 (GRCm39)	missense	probably benign	0.00
R4627:Vwa8	UTSW	14	79,341,137 (GRCm39)	critical splice donor site	probably null
R4835:Vwa8	UTSW	14	79,172,053 (GRCm39)	missense	probably benign	0.11
R4868:Vwa8	UTSW	14	79,420,522 (GRCm39)	missense	probably damaging	1.00
R4988:Vwa8	UTSW	14	79,435,723 (GRCm39)	missense	probably benign	0.05
R5137:Vwa8	UTSW	14	79,302,342 (GRCm39)	missense	probably damaging	1.00
R5156:Vwa8	UTSW	14	79,221,666 (GRCm39)	missense	probably benign	0.00
R5658:Vwa8	UTSW	14	79,219,838 (GRCm39)	critical splice donor site	probably null
R5841:Vwa8	UTSW	14	79,231,958 (GRCm39)	missense	probably benign
R6057:Vwa8	UTSW	14	79,320,313 (GRCm39)	missense	probably benign	0.21
R6244:Vwa8	UTSW	14	79,324,102 (GRCm39)	missense	probably benign
R6264:Vwa8	UTSW	14	79,324,252 (GRCm39)	missense	possibly damaging	0.64
R6290:Vwa8	UTSW	14	79,331,772 (GRCm39)	splice site	probably null
R6332:Vwa8	UTSW	14	79,434,904 (GRCm39)	missense	probably benign
R6395:Vwa8	UTSW	14	79,331,184 (GRCm39)	missense	probably benign	0.02
R6472:Vwa8	UTSW	14	79,246,610 (GRCm39)	missense	possibly damaging	0.71
R6497:Vwa8	UTSW	14	79,333,841 (GRCm39)	missense	probably benign	0.00
R6527:Vwa8	UTSW	14	79,184,653 (GRCm39)	missense	possibly damaging	0.73
R6552:Vwa8	UTSW	14	79,435,662 (GRCm39)	missense	possibly damaging	0.80
R6812:Vwa8	UTSW	14	79,434,859 (GRCm39)	missense	probably damaging	0.99
R6994:Vwa8	UTSW	14	79,145,596 (GRCm39)	missense	possibly damaging	0.90
R7040:Vwa8	UTSW	14	79,149,645 (GRCm39)	missense	probably damaging	1.00
R7357:Vwa8	UTSW	14	79,275,641 (GRCm39)	missense	probably null	1.00
R7363:Vwa8	UTSW	14	79,256,147 (GRCm39)	missense	probably benign	0.05
R7406:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7408:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7409:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7410:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7483:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7484:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7491:Vwa8	UTSW	14	79,320,254 (GRCm39)	missense	probably benign	0.24
R7500:Vwa8	UTSW	14	79,162,686 (GRCm39)	splice site	probably null
R7514:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7582:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7584:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7585:Vwa8	UTSW	14	79,219,674 (GRCm39)	critical splice acceptor site	probably null
R7647:Vwa8	UTSW	14	79,172,669 (GRCm39)	missense	probably damaging	0.99
R7685:Vwa8	UTSW	14	79,335,740 (GRCm39)	missense	probably benign
R7703:Vwa8	UTSW	14	79,263,513 (GRCm39)	missense	probably damaging	1.00
R7730:Vwa8	UTSW	14	79,232,589 (GRCm39)	missense	probably benign	0.00
R7775:Vwa8	UTSW	14	79,275,587 (GRCm39)	missense	probably benign	0.03
R7778:Vwa8	UTSW	14	79,275,587 (GRCm39)	missense	probably benign	0.03
R7824:Vwa8	UTSW	14	79,275,587 (GRCm39)	missense	probably benign	0.03
R7885:Vwa8	UTSW	14	79,258,089 (GRCm39)	missense	probably benign	0.00
R7902:Vwa8	UTSW	14	79,329,731 (GRCm39)	missense	probably benign	0.00
R8262:Vwa8	UTSW	14	79,171,272 (GRCm39)	critical splice donor site	probably null
R8458:Vwa8	UTSW	14	79,302,332 (GRCm39)	missense	probably damaging	1.00
R8495:Vwa8	UTSW	14	79,174,617 (GRCm39)	nonsense	probably null
R8557:Vwa8	UTSW	14	79,246,649 (GRCm39)	missense	probably damaging	1.00
R8841:Vwa8	UTSW	14	79,184,702 (GRCm39)	missense	probably benign	0.04
R8906:Vwa8	UTSW	14	79,329,815 (GRCm39)	missense	probably benign	0.00
R8947:Vwa8	UTSW	14	79,438,552 (GRCm39)	missense	probably damaging	1.00
R9034:Vwa8	UTSW	14	79,296,179 (GRCm39)	missense	probably damaging	1.00
R9051:Vwa8	UTSW	14	79,324,150 (GRCm39)	missense	probably benign	0.00
R9179:Vwa8	UTSW	14	79,335,801 (GRCm39)	missense	probably benign
R9433:Vwa8	UTSW	14	79,335,871 (GRCm39)	critical splice donor site	probably null
R9455:Vwa8	UTSW	14	79,300,115 (GRCm39)	missense	probably damaging	1.00
R9496:Vwa8	UTSW	14	79,258,122 (GRCm39)	missense	probably benign
R9530:Vwa8	UTSW	14	79,172,639 (GRCm39)	missense	probably benign	0.33
R9584:Vwa8	UTSW	14	79,394,549 (GRCm39)	missense	probably benign
R9763:Vwa8	UTSW	14	79,186,988 (GRCm39)	missense	probably damaging	1.00
Z1088:Vwa8	UTSW	14	79,219,686 (GRCm39)	missense	probably benign	0.38
Z1177:Vwa8	UTSW	14	79,296,132 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AACTGTGCCTGTCTTGTATAGG -3'
(R):5'- TCACACAGACTGATGCTCCTG -3'

Sequencing Primer
(F):5'- TCTCTTTACAGTATTGTTGAAAAGGG -3'
(R):5'- ACACAGACTGATGCTCCTGTTCTC -3'

Posted On

2019-09-13