Incidental Mutation 'R7395:Plb1'
| ID |
573719 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plb1
|
| Ensembl Gene |
ENSMUSG00000029134 |
| Gene Name |
phospholipase B1 |
| Synonyms |
4632413E21Rik, 4930433E17Rik, 4930539A06Rik |
| MMRRC Submission |
045477-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.055)
|
| Stock # |
R7395 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
32390035-32521700 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 32511028 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 1298
(K1298E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000098927
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000101376]
[ENSMUST00000202220]
|
| AlphaFold |
Q3TTY0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101376
AA Change: K1298E
PolyPhen 2
Score 0.297 (Sensitivity: 0.91; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000098927
Gene: ENSMUSG00000029134
AA Change: K1298E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
69 |
N/A |
INTRINSIC |
|
Pfam:Lipase_GDSL
|
398 |
672 |
4e-20 |
PFAM |
|
Pfam:Lipase_GDSL
|
745 |
1019 |
1.7e-17 |
PFAM |
|
Pfam:Lipase_GDSL
|
1101 |
1367 |
4.6e-15 |
PFAM |
|
transmembrane domain
|
1420 |
1442 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000202220
AA Change: K1298E
PolyPhen 2
Score 0.297 (Sensitivity: 0.91; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000144040
Gene: ENSMUSG00000029134
AA Change: K1298E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
69 |
N/A |
INTRINSIC |
|
Pfam:Lipase_GDSL
|
398 |
672 |
4e-20 |
PFAM |
|
Pfam:Lipase_GDSL
|
745 |
1019 |
1.7e-17 |
PFAM |
|
Pfam:Lipase_GDSL
|
1101 |
1367 |
4.6e-15 |
PFAM |
|
transmembrane domain
|
1420 |
1442 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
99% (92/93) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3830403N18Rik |
G |
T |
X: 55,184,140 (GRCm39) |
|
probably null |
Het |
| 4930433I11Rik |
A |
T |
7: 40,639,102 (GRCm39) |
T13S |
probably damaging |
Het |
| Abca13 |
A |
G |
11: 9,241,658 (GRCm39) |
I1174V |
probably benign |
Het |
| Acoxl |
G |
A |
2: 127,726,336 (GRCm39) |
V237M |
probably damaging |
Het |
| Adam33 |
A |
C |
2: 130,903,089 (GRCm39) |
W52G |
probably benign |
Het |
| Adgrv1 |
T |
C |
13: 81,707,467 (GRCm39) |
H1313R |
probably damaging |
Het |
| Ap3d1 |
T |
C |
10: 80,566,716 (GRCm39) |
T89A |
probably benign |
Het |
| Armc8 |
T |
C |
9: 99,415,185 (GRCm39) |
E165G |
probably damaging |
Het |
| Atp6v1c1 |
T |
C |
15: 38,691,949 (GRCm39) |
*383Q |
probably null |
Het |
| Atp8b4 |
A |
T |
2: 126,217,614 (GRCm39) |
L634Q |
possibly damaging |
Het |
| B3glct |
A |
G |
5: 149,649,069 (GRCm39) |
|
probably null |
Het |
| Bhlhe40 |
TG |
TGG |
6: 108,641,818 (GRCm39) |
254 |
probably null |
Het |
| Bicd2 |
A |
G |
13: 49,531,706 (GRCm39) |
D316G |
possibly damaging |
Het |
| Bop1 |
A |
T |
15: 76,338,041 (GRCm39) |
S610T |
probably damaging |
Het |
| Car11 |
T |
A |
7: 45,350,745 (GRCm39) |
Y80* |
probably null |
Het |
| Ccdc121rt2 |
A |
T |
5: 112,598,035 (GRCm39) |
E194V |
possibly damaging |
Het |
| Ccdc96 |
T |
C |
5: 36,642,609 (GRCm39) |
I205T |
probably benign |
Het |
| Ces2a |
A |
G |
8: 105,466,273 (GRCm39) |
E390G |
probably benign |
Het |
| Cfap54 |
C |
A |
10: 92,720,565 (GRCm39) |
V2630L |
unknown |
Het |
| Chek2 |
G |
T |
5: 111,019,974 (GRCm39) |
|
probably null |
Het |
| Cntn3 |
C |
T |
6: 102,314,355 (GRCm39) |
|
probably null |
Het |
| Cpne3 |
A |
T |
4: 19,528,239 (GRCm39) |
D339E |
probably damaging |
Het |
| Crocc2 |
C |
T |
1: 93,143,829 (GRCm39) |
Q1403* |
probably null |
Het |
| Crppa |
A |
T |
12: 36,551,994 (GRCm39) |
I283F |
possibly damaging |
Het |
| Csnka2ip |
G |
A |
16: 64,299,803 (GRCm39) |
T187I |
|
Het |
| Ctu1 |
A |
G |
7: 43,326,019 (GRCm39) |
H226R |
possibly damaging |
Het |
| Cubn |
G |
T |
2: 13,291,875 (GRCm39) |
Q3317K |
probably damaging |
Het |
| Cyp17a1 |
A |
G |
19: 46,659,134 (GRCm39) |
L169P |
probably benign |
Het |
| Dcc |
T |
A |
18: 71,507,640 (GRCm39) |
K911* |
probably null |
Het |
| Dcun1d2 |
G |
A |
8: 13,328,675 (GRCm39) |
R75* |
probably null |
Het |
| Defb19 |
A |
T |
2: 152,421,943 (GRCm39) |
|
probably null |
Het |
| Dffb |
A |
T |
4: 154,053,570 (GRCm39) |
S257R |
probably damaging |
Het |
| Dip2c |
A |
C |
13: 9,664,413 (GRCm39) |
N942T |
probably damaging |
Het |
| Dnah3 |
T |
A |
7: 119,565,474 (GRCm39) |
I169F |
|
Het |
| Dnah3 |
T |
C |
7: 119,660,183 (GRCm39) |
M830V |
probably benign |
Het |
| Dnajc5g |
G |
A |
5: 31,269,009 (GRCm39) |
S130N |
possibly damaging |
Het |
| Dscaml1 |
C |
A |
9: 45,613,703 (GRCm39) |
Q939K |
possibly damaging |
Het |
| Evpl |
G |
C |
11: 116,117,905 (GRCm39) |
N761K |
possibly damaging |
Het |
| Fbxw8 |
A |
T |
5: 118,206,280 (GRCm39) |
I556N |
probably damaging |
Het |
| Fry |
G |
T |
5: 150,304,348 (GRCm39) |
M579I |
possibly damaging |
Het |
| Ggt7 |
A |
T |
2: 155,337,800 (GRCm39) |
M488K |
probably benign |
Het |
| Gnpnat1 |
T |
A |
14: 45,619,038 (GRCm39) |
H107L |
probably benign |
Het |
| Golga2 |
C |
A |
2: 32,195,599 (GRCm39) |
P798Q |
possibly damaging |
Het |
| Gpr35 |
G |
A |
1: 92,910,929 (GRCm39) |
A214T |
probably damaging |
Het |
| Greb1 |
A |
T |
12: 16,759,431 (GRCm39) |
|
probably null |
Het |
| Hdac10 |
G |
A |
15: 89,012,487 (GRCm39) |
T32I |
probably benign |
Het |
| Hkdc1 |
G |
A |
10: 62,221,478 (GRCm39) |
T860I |
probably damaging |
Het |
| Icam5 |
C |
A |
9: 20,946,738 (GRCm39) |
P422Q |
possibly damaging |
Het |
| Ist1 |
A |
C |
8: 110,404,159 (GRCm39) |
S238A |
probably benign |
Het |
| Lrig2 |
T |
C |
3: 104,404,836 (GRCm39) |
N91D |
probably benign |
Het |
| Mapt |
A |
C |
11: 104,218,949 (GRCm39) |
D352A |
probably damaging |
Het |
| Micall2 |
G |
A |
5: 139,702,124 (GRCm39) |
P373L |
possibly damaging |
Het |
| Mocs1 |
A |
G |
17: 49,761,585 (GRCm39) |
S560G |
possibly damaging |
Het |
| Mpo |
A |
G |
11: 87,691,950 (GRCm39) |
D461G |
probably damaging |
Het |
| Myo1a |
G |
T |
10: 127,546,309 (GRCm39) |
V271L |
probably damaging |
Het |
| Ncoa1 |
G |
A |
12: 4,345,188 (GRCm39) |
P720S |
not run |
Het |
| Ncr1 |
T |
A |
7: 4,341,150 (GRCm39) |
I47N |
probably damaging |
Het |
| Ndufb6 |
G |
A |
4: 40,277,730 (GRCm39) |
R66C |
probably damaging |
Het |
| Obox5 |
A |
T |
7: 15,492,668 (GRCm39) |
S208C |
probably damaging |
Het |
| Or10q1 |
T |
C |
19: 13,726,502 (GRCm39) |
S11P |
probably damaging |
Het |
| Or2n1d |
A |
T |
17: 38,646,755 (GRCm39) |
K236* |
probably null |
Het |
| Or5p75-ps1 |
T |
A |
7: 108,107,611 (GRCm39) |
F116Y |
unknown |
Het |
| Or7d9 |
T |
A |
9: 20,197,826 (GRCm39) |
M285K |
probably damaging |
Het |
| Padi4 |
A |
C |
4: 140,488,983 (GRCm39) |
V152G |
probably damaging |
Het |
| Pdzd7 |
A |
T |
19: 45,025,450 (GRCm39) |
D348E |
probably damaging |
Het |
| Pdzph1 |
T |
A |
17: 59,186,154 (GRCm39) |
K1212N |
possibly damaging |
Het |
| Piezo2 |
C |
T |
18: 63,160,634 (GRCm39) |
G2341R |
probably damaging |
Het |
| Prr14l |
A |
G |
5: 32,985,982 (GRCm39) |
L1171P |
probably benign |
Het |
| Rab11fip5 |
T |
C |
6: 85,318,850 (GRCm39) |
T680A |
probably benign |
Het |
| Rev1 |
A |
T |
1: 38,127,146 (GRCm39) |
N371K |
possibly damaging |
Het |
| Rsf1 |
CGGCGGCGG |
CGGCGGCGGGGGCGGCGG |
7: 97,229,133 (GRCm39) |
|
probably benign |
Het |
| Ryr2 |
A |
G |
13: 11,799,997 (GRCm39) |
C917R |
probably damaging |
Het |
| Sall1 |
A |
T |
8: 89,757,549 (GRCm39) |
S852T |
possibly damaging |
Het |
| Serpine2 |
A |
G |
1: 79,779,272 (GRCm39) |
F296L |
probably damaging |
Het |
| Slc12a6 |
A |
T |
2: 112,182,887 (GRCm39) |
N754I |
probably damaging |
Het |
| Slc39a6 |
A |
T |
18: 24,718,332 (GRCm39) |
L575Q |
probably damaging |
Het |
| Smarcc2 |
T |
A |
10: 128,321,475 (GRCm39) |
L890Q |
probably damaging |
Het |
| Smg5 |
T |
A |
3: 88,268,378 (GRCm39) |
V1006D |
probably damaging |
Het |
| Ssh2 |
T |
C |
11: 77,283,899 (GRCm39) |
V51A |
probably damaging |
Het |
| St14 |
T |
C |
9: 31,008,195 (GRCm39) |
K547E |
probably benign |
Het |
| Stag1 |
T |
G |
9: 100,678,781 (GRCm39) |
V234G |
probably damaging |
Het |
| Stag3 |
A |
T |
5: 138,280,207 (GRCm39) |
Q24L |
probably benign |
Het |
| Stra6 |
T |
C |
9: 58,048,380 (GRCm39) |
Y158H |
probably damaging |
Het |
| Tcstv1a |
A |
T |
13: 120,355,666 (GRCm39) |
|
probably null |
Het |
| Tmem196 |
G |
A |
12: 119,975,002 (GRCm39) |
C62Y |
probably damaging |
Het |
| Tmem265 |
T |
A |
7: 127,164,039 (GRCm39) |
F84L |
|
Het |
| Tph1 |
C |
T |
7: 46,306,627 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
G |
2: 76,776,834 (GRCm39) |
I1522T |
unknown |
Het |
| Ulk4 |
T |
A |
9: 121,084,178 (GRCm39) |
Q129L |
probably benign |
Het |
| Usp17la |
T |
A |
7: 104,510,792 (GRCm39) |
S466T |
probably benign |
Het |
| Vmn2r31 |
A |
T |
7: 7,387,744 (GRCm39) |
V609E |
probably damaging |
Het |
| Vmn2r52 |
C |
T |
7: 9,904,744 (GRCm39) |
C365Y |
probably benign |
Het |
| Zbtb4 |
A |
T |
11: 69,666,937 (GRCm39) |
T81S |
possibly damaging |
Het |
| Zfp605 |
A |
T |
5: 110,259,885 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Plb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00096:Plb1
|
APN |
5 |
32,503,080 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00542:Plb1
|
APN |
5 |
32,427,178 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00835:Plb1
|
APN |
5 |
32,521,516 (GRCm39) |
missense |
unknown |
|
|
IGL00954:Plb1
|
APN |
5 |
32,455,858 (GRCm39) |
splice site |
probably benign |
|
|
IGL01350:Plb1
|
APN |
5 |
32,474,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01527:Plb1
|
APN |
5 |
32,474,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01599:Plb1
|
APN |
5 |
32,499,888 (GRCm39) |
splice site |
probably benign |
|
|
IGL01690:Plb1
|
APN |
5 |
32,471,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01813:Plb1
|
APN |
5 |
32,486,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01826:Plb1
|
APN |
5 |
32,438,489 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02263:Plb1
|
APN |
5 |
32,478,692 (GRCm39) |
splice site |
probably benign |
|
|
IGL02314:Plb1
|
APN |
5 |
32,438,492 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02649:Plb1
|
APN |
5 |
32,519,912 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02701:Plb1
|
APN |
5 |
32,521,541 (GRCm39) |
missense |
unknown |
|
|
IGL02704:Plb1
|
APN |
5 |
32,511,011 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL03170:Plb1
|
APN |
5 |
32,442,246 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03182:Plb1
|
APN |
5 |
32,502,259 (GRCm39) |
splice site |
probably benign |
|
|
IGL03326:Plb1
|
APN |
5 |
32,488,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03046:Plb1
|
UTSW |
5 |
32,485,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Plb1
|
UTSW |
5 |
32,506,959 (GRCm39) |
splice site |
probably benign |
|
|
R0013:Plb1
|
UTSW |
5 |
32,506,959 (GRCm39) |
splice site |
probably benign |
|
|
R0034:Plb1
|
UTSW |
5 |
32,430,457 (GRCm39) |
missense |
probably benign |
0.16 |
|
R0034:Plb1
|
UTSW |
5 |
32,430,457 (GRCm39) |
missense |
probably benign |
0.16 |
|
R0330:Plb1
|
UTSW |
5 |
32,512,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0413:Plb1
|
UTSW |
5 |
32,512,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0721:Plb1
|
UTSW |
5 |
32,521,539 (GRCm39) |
missense |
unknown |
|
|
R0735:Plb1
|
UTSW |
5 |
32,442,264 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1423:Plb1
|
UTSW |
5 |
32,450,601 (GRCm39) |
missense |
probably benign |
|
|
R1428:Plb1
|
UTSW |
5 |
32,422,256 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1469:Plb1
|
UTSW |
5 |
32,512,170 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1469:Plb1
|
UTSW |
5 |
32,512,170 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1694:Plb1
|
UTSW |
5 |
32,474,621 (GRCm39) |
missense |
probably null |
0.01 |
|
R1801:Plb1
|
UTSW |
5 |
32,450,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1804:Plb1
|
UTSW |
5 |
32,511,041 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1900:Plb1
|
UTSW |
5 |
32,444,191 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1903:Plb1
|
UTSW |
5 |
32,448,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:Plb1
|
UTSW |
5 |
32,507,004 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2153:Plb1
|
UTSW |
5 |
32,471,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2207:Plb1
|
UTSW |
5 |
32,473,984 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2270:Plb1
|
UTSW |
5 |
32,450,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Plb1
|
UTSW |
5 |
32,450,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2311:Plb1
|
UTSW |
5 |
32,427,162 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2850:Plb1
|
UTSW |
5 |
32,450,568 (GRCm39) |
missense |
probably benign |
|
|
R3103:Plb1
|
UTSW |
5 |
32,485,373 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4444:Plb1
|
UTSW |
5 |
32,487,909 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4559:Plb1
|
UTSW |
5 |
32,490,175 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4577:Plb1
|
UTSW |
5 |
32,404,901 (GRCm39) |
nonsense |
probably null |
|
|
R4578:Plb1
|
UTSW |
5 |
32,404,901 (GRCm39) |
nonsense |
probably null |
|
|
R4739:Plb1
|
UTSW |
5 |
32,507,023 (GRCm39) |
splice site |
probably null |
|
|
R4747:Plb1
|
UTSW |
5 |
32,507,003 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4806:Plb1
|
UTSW |
5 |
32,447,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5406:Plb1
|
UTSW |
5 |
32,499,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Plb1
|
UTSW |
5 |
32,521,543 (GRCm39) |
missense |
unknown |
|
|
R5574:Plb1
|
UTSW |
5 |
32,487,291 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5588:Plb1
|
UTSW |
5 |
32,487,293 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5619:Plb1
|
UTSW |
5 |
32,490,841 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5769:Plb1
|
UTSW |
5 |
32,474,866 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6366:Plb1
|
UTSW |
5 |
32,471,429 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R6700:Plb1
|
UTSW |
5 |
32,490,808 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7162:Plb1
|
UTSW |
5 |
32,507,007 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7379:Plb1
|
UTSW |
5 |
32,502,983 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7426:Plb1
|
UTSW |
5 |
32,478,591 (GRCm39) |
splice site |
probably null |
|
|
R7643:Plb1
|
UTSW |
5 |
32,404,901 (GRCm39) |
nonsense |
probably null |
|
|
R7657:Plb1
|
UTSW |
5 |
32,487,211 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7780:Plb1
|
UTSW |
5 |
32,483,610 (GRCm39) |
splice site |
probably null |
|
|
R8040:Plb1
|
UTSW |
5 |
32,430,413 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8212:Plb1
|
UTSW |
5 |
32,422,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8312:Plb1
|
UTSW |
5 |
32,485,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Plb1
|
UTSW |
5 |
32,460,023 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8770:Plb1
|
UTSW |
5 |
32,404,853 (GRCm39) |
missense |
unknown |
|
|
R8857:Plb1
|
UTSW |
5 |
32,521,556 (GRCm39) |
missense |
unknown |
|
|
R9029:Plb1
|
UTSW |
5 |
32,439,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9110:Plb1
|
UTSW |
5 |
32,521,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9765:Plb1
|
UTSW |
5 |
32,512,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0018:Plb1
|
UTSW |
5 |
32,443,227 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0019:Plb1
|
UTSW |
5 |
32,511,041 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0027:Plb1
|
UTSW |
5 |
32,427,702 (GRCm39) |
missense |
probably benign |
|
|
X0028:Plb1
|
UTSW |
5 |
32,460,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Plb1
|
UTSW |
5 |
32,468,261 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Plb1
|
UTSW |
5 |
32,468,191 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Plb1
|
UTSW |
5 |
32,442,241 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAACCACATTCCTGAGTTAAGGC -3'
(R):5'- CCCCAGGTAAATAGTGTGAGG -3'
Sequencing Primer
(F):5'- GACTTAGACCCAAGTGTTTTAGGC -3'
(R):5'- TAAATAGTGTGAGGAATAGGATCTCC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation