Incidental Mutation 'R7399:Ptprf'
| ID |
574012 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ptprf
|
| Ensembl Gene |
ENSMUSG00000033295 |
| Gene Name |
protein tyrosine phosphatase receptor type F |
| Synonyms |
RPTP-LAR, LAR |
| MMRRC Submission |
045481-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.657)
|
| Stock # |
R7399 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
118065410-118148602 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 118083720 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 788
(V788I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039368
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000049074]
|
| AlphaFold |
A2A8L5 |
| PDB Structure |
Tandem Ig domains of tyrosine phosphatase LAR [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000049074
AA Change: V788I
PolyPhen 2
Score 0.277 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000039368
Gene: ENSMUSG00000033295
AA Change: V788I
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
45 |
114 |
2.64e-12 |
SMART |
|
IGc2
|
147 |
214 |
1.48e-15 |
SMART |
|
IG
|
238 |
316 |
1.06e-11 |
SMART |
|
FN3
|
319 |
398 |
6.9e-14 |
SMART |
|
FN3
|
414 |
497 |
5.73e-11 |
SMART |
|
FN3
|
512 |
591 |
4.06e-11 |
SMART |
|
FN3
|
606 |
693 |
8.69e-11 |
SMART |
|
FN3
|
709 |
797 |
8.83e-12 |
SMART |
|
FN3
|
812 |
892 |
3.2e-9 |
SMART |
|
FN3
|
907 |
988 |
2.53e-12 |
SMART |
|
FN3
|
1003 |
1079 |
3.48e-1 |
SMART |
|
coiled coil region
|
1146 |
1175 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1253 |
1275 |
N/A |
INTRINSIC |
|
PTPc
|
1342 |
1600 |
1.12e-138 |
SMART |
|
PTPc
|
1629 |
1891 |
3.4e-129 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000119954
Gene: ENSMUSG00000033295
AA Change: V210I
| Domain | Start | End | E-Value | Type |
|---|
|
FN3
|
37 |
116 |
4.06e-11 |
SMART |
|
FN3
|
132 |
220 |
8.83e-12 |
SMART |
|
FN3
|
235 |
315 |
3.2e-9 |
SMART |
|
FN3
|
330 |
411 |
2.53e-12 |
SMART |
|
FN3
|
426 |
502 |
3.48e-1 |
SMART |
|
coiled coil region
|
568 |
597 |
N/A |
INTRINSIC |
|
transmembrane domain
|
676 |
698 |
N/A |
INTRINSIC |
|
PTPc
|
776 |
1034 |
1.12e-138 |
SMART |
|
PTPc
|
1063 |
1325 |
3.4e-129 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000117313
Gene: ENSMUSG00000033295
AA Change: V362I
| Domain | Start | End | E-Value | Type |
|---|
|
FN3
|
14 |
66 |
2.7e1 |
SMART |
|
FN3
|
82 |
165 |
5.73e-11 |
SMART |
|
FN3
|
180 |
259 |
4.06e-11 |
SMART |
|
FN3
|
275 |
372 |
6.69e-12 |
SMART |
|
FN3
|
385 |
461 |
2.83e-1 |
SMART |
|
coiled coil region
|
527 |
556 |
N/A |
INTRINSIC |
|
transmembrane domain
|
635 |
657 |
N/A |
INTRINSIC |
|
PTPc
|
735 |
993 |
1.12e-138 |
SMART |
|
PTPc
|
1022 |
1284 |
3.4e-129 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
99% (74/75) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null females have premature involution of the mammary glands leading to an inability to feed pups. Other characteristics of null mice include defective nerve regeneration and hyperactivity. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 74 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaca |
T |
G |
11: 84,151,505 (GRCm39) |
V801G |
possibly damaging |
Het |
| Actbl2 |
T |
A |
13: 111,392,127 (GRCm39) |
M154K |
probably benign |
Het |
| Adam7 |
A |
T |
14: 68,741,915 (GRCm39) |
|
probably null |
Het |
| Arfgef1 |
T |
A |
1: 10,251,122 (GRCm39) |
T888S |
probably benign |
Het |
| AW554918 |
C |
T |
18: 25,302,117 (GRCm39) |
P10L |
possibly damaging |
Het |
| Bcap29 |
A |
G |
12: 31,680,881 (GRCm39) |
I35T |
probably damaging |
Het |
| Bhlhe40 |
TG |
TGG |
6: 108,641,818 (GRCm39) |
254 |
probably null |
Het |
| Cby2 |
A |
G |
14: 75,830,077 (GRCm39) |
S39P |
probably benign |
Het |
| Cdc25b |
A |
G |
2: 131,036,574 (GRCm39) |
D458G |
probably damaging |
Het |
| Cdc42bpb |
T |
C |
12: 111,272,101 (GRCm39) |
K1104R |
probably benign |
Het |
| Cep89 |
A |
G |
7: 35,137,803 (GRCm39) |
N729S |
probably damaging |
Het |
| Clec4a4 |
T |
A |
6: 122,968,788 (GRCm39) |
M51K |
possibly damaging |
Het |
| Dcdc2b |
A |
G |
4: 129,503,422 (GRCm39) |
L270P |
probably damaging |
Het |
| Dennd5b |
G |
T |
6: 148,937,981 (GRCm39) |
H639N |
probably damaging |
Het |
| Dnah11 |
T |
G |
12: 117,991,212 (GRCm39) |
T2385P |
probably benign |
Het |
| Dnah11 |
T |
C |
12: 118,089,520 (GRCm39) |
E1182G |
probably damaging |
Het |
| Dok7 |
T |
C |
5: 35,223,815 (GRCm39) |
V81A |
probably damaging |
Het |
| Dtx1 |
T |
A |
5: 120,820,458 (GRCm39) |
M494L |
possibly damaging |
Het |
| Foxj1 |
A |
T |
11: 116,223,080 (GRCm39) |
L241Q |
possibly damaging |
Het |
| Gbp10 |
G |
A |
5: 105,384,015 (GRCm39) |
|
probably benign |
Het |
| Hnmt |
T |
A |
2: 23,893,892 (GRCm39) |
T201S |
probably benign |
Het |
| Jup |
G |
T |
11: 100,269,177 (GRCm39) |
T412K |
possibly damaging |
Het |
| Kcnh2 |
G |
A |
5: 24,527,057 (GRCm39) |
S954F |
probably damaging |
Het |
| Klhdc7b |
A |
C |
15: 89,272,847 (GRCm39) |
K585T |
possibly damaging |
Het |
| Klk7 |
T |
A |
7: 43,461,424 (GRCm39) |
S14T |
probably benign |
Het |
| Lama4 |
G |
A |
10: 38,923,944 (GRCm39) |
E451K |
probably damaging |
Het |
| Ldhb |
A |
G |
6: 142,441,399 (GRCm39) |
C164R |
probably damaging |
Het |
| Malrd1 |
G |
A |
2: 15,614,901 (GRCm39) |
D239N |
|
Het |
| Mgam |
T |
A |
6: 40,643,788 (GRCm39) |
V572E |
probably damaging |
Het |
| Mrgprb2 |
G |
T |
7: 48,201,890 (GRCm39) |
N278K |
probably damaging |
Het |
| Msto1 |
A |
G |
3: 88,819,130 (GRCm39) |
Y206H |
probably damaging |
Het |
| Myo6 |
A |
G |
9: 80,169,573 (GRCm39) |
S467G |
unknown |
Het |
| Mysm1 |
T |
A |
4: 94,849,964 (GRCm39) |
I447L |
probably benign |
Het |
| Nav3 |
T |
C |
10: 109,688,795 (GRCm39) |
E494G |
possibly damaging |
Het |
| Nol10 |
T |
G |
12: 17,452,174 (GRCm39) |
V376G |
probably damaging |
Het |
| Nup205 |
T |
A |
6: 35,191,611 (GRCm39) |
I1032N |
probably damaging |
Het |
| Oog2 |
A |
G |
4: 143,921,851 (GRCm39) |
K254E |
probably benign |
Het |
| Or10ac1 |
A |
G |
6: 42,515,662 (GRCm39) |
F98S |
possibly damaging |
Het |
| Or52z12 |
A |
T |
7: 103,233,588 (GRCm39) |
I120L |
possibly damaging |
Het |
| Or5b98 |
A |
G |
19: 12,931,811 (GRCm39) |
N286S |
probably damaging |
Het |
| Or5d41 |
A |
T |
2: 88,055,366 (GRCm39) |
Y3* |
probably null |
Het |
| Or5g25 |
T |
A |
2: 85,477,768 (GRCm39) |
D299V |
possibly damaging |
Het |
| Or5g27 |
A |
G |
2: 85,409,640 (GRCm39) |
D19G |
probably benign |
Het |
| Or6b1 |
T |
G |
6: 42,815,680 (GRCm39) |
Y288* |
probably null |
Het |
| Or6c6 |
A |
T |
10: 129,186,426 (GRCm39) |
|
probably benign |
Het |
| Or8h10 |
G |
A |
2: 86,808,501 (GRCm39) |
T213I |
probably benign |
Het |
| Osbpl11 |
T |
A |
16: 33,056,649 (GRCm39) |
D694E |
probably benign |
Het |
| Pcm1 |
T |
A |
8: 41,746,547 (GRCm39) |
Y1210N |
probably benign |
Het |
| Pdxk |
T |
C |
10: 78,276,697 (GRCm39) |
M293V |
probably benign |
Het |
| Plcb3 |
T |
C |
19: 6,940,235 (GRCm39) |
I451V |
probably benign |
Het |
| Plekhm2 |
A |
G |
4: 141,361,687 (GRCm39) |
F272S |
probably damaging |
Het |
| Pramel32 |
C |
A |
4: 88,546,202 (GRCm39) |
R380L |
probably benign |
Het |
| Ptgdr |
A |
T |
14: 45,095,689 (GRCm39) |
|
probably null |
Het |
| Ralbp1 |
C |
T |
17: 66,161,143 (GRCm39) |
V467I |
probably benign |
Het |
| Ralgds |
A |
C |
2: 28,433,667 (GRCm39) |
Q229P |
possibly damaging |
Het |
| Recql |
T |
C |
6: 142,320,610 (GRCm39) |
D146G |
probably damaging |
Het |
| Reln |
T |
C |
5: 22,256,365 (GRCm39) |
N493S |
probably damaging |
Het |
| Rfxank |
C |
T |
8: 70,587,936 (GRCm39) |
|
probably null |
Het |
| Scn5a |
A |
T |
9: 119,315,596 (GRCm39) |
M1704K |
probably damaging |
Het |
| Slc7a7 |
G |
T |
14: 54,611,725 (GRCm39) |
A316E |
possibly damaging |
Het |
| Slco1a6 |
A |
T |
6: 142,036,794 (GRCm39) |
C538S |
probably benign |
Het |
| Stard6 |
T |
C |
18: 70,631,718 (GRCm39) |
|
probably null |
Het |
| Strip2 |
T |
A |
6: 29,927,612 (GRCm39) |
M219K |
possibly damaging |
Het |
| Tcam1 |
T |
C |
11: 106,174,911 (GRCm39) |
V122A |
probably damaging |
Het |
| Tha1 |
A |
G |
11: 117,760,516 (GRCm39) |
V236A |
possibly damaging |
Het |
| Tmem201 |
A |
T |
4: 149,815,554 (GRCm39) |
I132N |
possibly damaging |
Het |
| Tnc |
T |
C |
4: 63,938,894 (GRCm39) |
|
probably benign |
Het |
| Vmn1r42 |
T |
C |
6: 89,822,495 (GRCm39) |
T25A |
probably benign |
Het |
| Vmn2r94 |
T |
A |
17: 18,464,765 (GRCm39) |
|
probably null |
Het |
| Wdfy4 |
A |
C |
14: 32,790,863 (GRCm39) |
V2188G |
|
Het |
| Zfp623 |
T |
C |
15: 75,819,247 (GRCm39) |
S68P |
probably damaging |
Het |
| Zfp950 |
A |
T |
19: 61,107,593 (GRCm39) |
C497S |
probably damaging |
Het |
| Zkscan2 |
C |
T |
7: 123,079,327 (GRCm39) |
E877K |
probably damaging |
Het |
| Zp3r |
C |
A |
1: 130,504,790 (GRCm39) |
V536L |
probably damaging |
Het |
|
| Other mutations in Ptprf |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Ptprf
|
APN |
4 |
118,080,417 (GRCm39) |
splice site |
probably benign |
|
|
IGL01337:Ptprf
|
APN |
4 |
118,093,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Ptprf
|
APN |
4 |
118,069,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01743:Ptprf
|
APN |
4 |
118,106,095 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01987:Ptprf
|
APN |
4 |
118,134,567 (GRCm39) |
missense |
probably benign |
|
|
IGL02189:Ptprf
|
APN |
4 |
118,070,839 (GRCm39) |
splice site |
probably benign |
|
|
IGL03067:Ptprf
|
APN |
4 |
118,067,910 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
PIT4677001:Ptprf
|
UTSW |
4 |
118,070,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0382:Ptprf
|
UTSW |
4 |
118,080,591 (GRCm39) |
splice site |
probably benign |
|
|
R0788:Ptprf
|
UTSW |
4 |
118,083,663 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1164:Ptprf
|
UTSW |
4 |
118,114,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1478:Ptprf
|
UTSW |
4 |
118,069,302 (GRCm39) |
nonsense |
probably null |
|
|
R1483:Ptprf
|
UTSW |
4 |
118,093,161 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1611:Ptprf
|
UTSW |
4 |
118,093,430 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1721:Ptprf
|
UTSW |
4 |
118,082,096 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1817:Ptprf
|
UTSW |
4 |
118,080,462 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1818:Ptprf
|
UTSW |
4 |
118,067,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1860:Ptprf
|
UTSW |
4 |
118,081,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2208:Ptprf
|
UTSW |
4 |
118,126,369 (GRCm39) |
splice site |
probably benign |
|
|
R2406:Ptprf
|
UTSW |
4 |
118,126,501 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R2912:Ptprf
|
UTSW |
4 |
118,106,177 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3111:Ptprf
|
UTSW |
4 |
118,068,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3498:Ptprf
|
UTSW |
4 |
118,082,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3499:Ptprf
|
UTSW |
4 |
118,082,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3615:Ptprf
|
UTSW |
4 |
118,095,080 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3616:Ptprf
|
UTSW |
4 |
118,095,080 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4038:Ptprf
|
UTSW |
4 |
118,114,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4243:Ptprf
|
UTSW |
4 |
118,083,649 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4260:Ptprf
|
UTSW |
4 |
118,083,280 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4693:Ptprf
|
UTSW |
4 |
118,068,219 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4726:Ptprf
|
UTSW |
4 |
118,069,414 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4746:Ptprf
|
UTSW |
4 |
118,082,236 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4802:Ptprf
|
UTSW |
4 |
118,067,526 (GRCm39) |
intron |
probably benign |
|
|
R4857:Ptprf
|
UTSW |
4 |
118,074,394 (GRCm39) |
splice site |
probably benign |
|
|
R5071:Ptprf
|
UTSW |
4 |
118,069,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5221:Ptprf
|
UTSW |
4 |
118,082,305 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5327:Ptprf
|
UTSW |
4 |
118,093,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5336:Ptprf
|
UTSW |
4 |
118,092,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5356:Ptprf
|
UTSW |
4 |
118,083,535 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5373:Ptprf
|
UTSW |
4 |
118,083,238 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5555:Ptprf
|
UTSW |
4 |
118,082,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5693:Ptprf
|
UTSW |
4 |
118,093,374 (GRCm39) |
nonsense |
probably null |
|
|
R5860:Ptprf
|
UTSW |
4 |
118,068,486 (GRCm39) |
intron |
probably benign |
|
|
R5869:Ptprf
|
UTSW |
4 |
118,067,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5890:Ptprf
|
UTSW |
4 |
118,081,932 (GRCm39) |
missense |
probably benign |
|
|
R5932:Ptprf
|
UTSW |
4 |
118,068,964 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6028:Ptprf
|
UTSW |
4 |
118,070,826 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6030:Ptprf
|
UTSW |
4 |
118,068,245 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6030:Ptprf
|
UTSW |
4 |
118,068,245 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6088:Ptprf
|
UTSW |
4 |
118,067,952 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6089:Ptprf
|
UTSW |
4 |
118,068,281 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6108:Ptprf
|
UTSW |
4 |
118,080,453 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6320:Ptprf
|
UTSW |
4 |
118,070,011 (GRCm39) |
missense |
probably benign |
|
|
R6741:Ptprf
|
UTSW |
4 |
118,080,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6744:Ptprf
|
UTSW |
4 |
118,093,562 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6750:Ptprf
|
UTSW |
4 |
118,088,928 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6906:Ptprf
|
UTSW |
4 |
118,126,474 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7021:Ptprf
|
UTSW |
4 |
118,081,101 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7153:Ptprf
|
UTSW |
4 |
118,088,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7326:Ptprf
|
UTSW |
4 |
118,088,866 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7337:Ptprf
|
UTSW |
4 |
118,068,322 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7374:Ptprf
|
UTSW |
4 |
118,114,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7375:Ptprf
|
UTSW |
4 |
118,070,011 (GRCm39) |
missense |
probably benign |
|
|
R7417:Ptprf
|
UTSW |
4 |
118,069,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7448:Ptprf
|
UTSW |
4 |
118,092,864 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7530:Ptprf
|
UTSW |
4 |
118,069,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7593:Ptprf
|
UTSW |
4 |
118,069,593 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Ptprf
|
UTSW |
4 |
118,068,275 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8239:Ptprf
|
UTSW |
4 |
118,069,309 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8257:Ptprf
|
UTSW |
4 |
118,083,476 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8331:Ptprf
|
UTSW |
4 |
118,083,263 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8441:Ptprf
|
UTSW |
4 |
118,075,255 (GRCm39) |
splice site |
probably benign |
|
|
R8681:Ptprf
|
UTSW |
4 |
118,088,844 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8771:Ptprf
|
UTSW |
4 |
118,068,987 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8815:Ptprf
|
UTSW |
4 |
118,095,125 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8998:Ptprf
|
UTSW |
4 |
118,083,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8999:Ptprf
|
UTSW |
4 |
118,083,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9389:Ptprf
|
UTSW |
4 |
118,093,236 (GRCm39) |
missense |
probably benign |
|
|
R9508:Ptprf
|
UTSW |
4 |
118,126,776 (GRCm39) |
nonsense |
probably null |
|
|
R9581:Ptprf
|
UTSW |
4 |
118,092,257 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0067:Ptprf
|
UTSW |
4 |
118,093,223 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
Z1177:Ptprf
|
UTSW |
4 |
118,126,812 (GRCm39) |
missense |
probably benign |
0.04 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATTGGAGACGGTAGCCCAG -3'
(R):5'- AGGATTTGTCCAGCTTCACCTC -3'
Sequencing Primer
(F):5'- TAGCCCAGCAGCTCTCCAG -3'
(R):5'- GTCCAGCTTCACCTCCCAGG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation