Incidental Mutation 'R7417:Prdm2'
| ID |
575374 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prdm2
|
| Ensembl Gene |
ENSMUSG00000057637 |
| Gene Name |
PR domain containing 2, with ZNF domain |
| Synonyms |
KMT8, LOC381568, Riz, E330024L24Rik, 4833427P12Rik, Riz1 |
| MMRRC Submission |
045495-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7417 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
142833961-142939560 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 142905869 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Asparagine
at position 73
(Y73N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101404
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000105778]
[ENSMUST00000134791]
[ENSMUST00000154280]
|
| AlphaFold |
A2A7B5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105778
AA Change: Y73N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000101404
Gene: ENSMUSG00000057637
AA Change: Y73N
| Domain | Start | End | E-Value | Type |
|---|
|
SET
|
29 |
146 |
2.79e-21 |
SMART |
|
coiled coil region
|
254 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
333 |
346 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
356 |
378 |
2.95e-3 |
SMART |
|
ZnF_C2H2
|
386 |
408 |
4.79e-3 |
SMART |
|
ZnF_C2H2
|
477 |
500 |
4.17e-3 |
SMART |
|
low complexity region
|
517 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
697 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
744 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
951 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
992 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1035 |
1080 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1126 |
1148 |
3.52e-1 |
SMART |
|
ZnF_C2H2
|
1154 |
1177 |
7.55e-1 |
SMART |
|
ZnF_C2H2
|
1183 |
1206 |
4.72e-2 |
SMART |
|
low complexity region
|
1239 |
1253 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1324 |
1344 |
5.12e1 |
SMART |
|
low complexity region
|
1406 |
1423 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1446 |
1466 |
1.86e1 |
SMART |
|
low complexity region
|
1475 |
1507 |
N/A |
INTRINSIC |
|
low complexity region
|
1551 |
1568 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000134791
|
| SMART Domains |
Protein: ENSMUSP00000116458
Gene: ENSMUSG00000057637
| Domain | Start | End | E-Value | Type |
|---|
|
SET
|
29 |
137 |
1.35e-19 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000154280
AA Change: Y73N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000117741
Gene: ENSMUSG00000057637
AA Change: Y73N
| Domain | Start | End | E-Value | Type |
|---|
|
SET
|
29 |
146 |
2.79e-21 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
100% (79/79) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
PHENOTYPE: Homozygous null mice have shortened life spans, becoming moribund due to increased incidence of tumors. Mice had a broad spectrum of unusual tumors in multiple organs, with a high incidence of diffuse large B cell lymphomas. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A530064D06Rik |
G |
A |
17: 48,460,057 (GRCm39) |
T213I |
probably damaging |
Het |
| Akr1b7 |
G |
A |
6: 34,394,300 (GRCm39) |
|
probably null |
Het |
| Aldh6a1 |
T |
C |
12: 84,488,556 (GRCm39) |
Q110R |
probably benign |
Het |
| Alg11 |
A |
T |
8: 22,552,044 (GRCm39) |
T63S |
probably benign |
Het |
| Ankrd13b |
A |
G |
11: 77,367,020 (GRCm39) |
Y271H |
probably damaging |
Het |
| Ano8 |
T |
A |
8: 71,933,477 (GRCm39) |
D605V |
unknown |
Het |
| Best2 |
C |
T |
8: 85,736,295 (GRCm39) |
|
probably null |
Het |
| Brca1 |
A |
G |
11: 101,415,807 (GRCm39) |
S776P |
probably damaging |
Het |
| Capn7 |
T |
C |
14: 31,092,663 (GRCm39) |
Y737H |
probably damaging |
Het |
| Cblc |
A |
T |
7: 19,522,899 (GRCm39) |
S333T |
probably benign |
Het |
| Ccm2 |
T |
A |
11: 6,543,091 (GRCm39) |
M257K |
probably benign |
Het |
| Cd320 |
T |
A |
17: 34,066,530 (GRCm39) |
C103* |
probably null |
Het |
| Cd53 |
A |
G |
3: 106,676,235 (GRCm39) |
F44S |
probably benign |
Het |
| Col9a2 |
G |
A |
4: 120,911,489 (GRCm39) |
R610H |
not run |
Het |
| Cubn |
T |
C |
2: 13,431,778 (GRCm39) |
I1272V |
probably benign |
Het |
| Cyp2j7 |
C |
T |
4: 96,090,225 (GRCm39) |
|
probably null |
Het |
| Dmrt2 |
A |
T |
19: 25,655,962 (GRCm39) |
R520S |
probably benign |
Het |
| Dnai3 |
A |
T |
3: 145,798,835 (GRCm39) |
|
probably null |
Het |
| Drg2 |
A |
G |
11: 60,345,506 (GRCm39) |
M1V |
probably null |
Het |
| Ect2 |
A |
G |
3: 27,152,568 (GRCm39) |
S908P |
probably damaging |
Het |
| Eipr1 |
A |
G |
12: 28,916,954 (GRCm39) |
T341A |
probably benign |
Het |
| Ell3 |
A |
C |
2: 121,270,891 (GRCm39) |
I214R |
probably benign |
Het |
| Emsy |
A |
T |
7: 98,264,693 (GRCm39) |
L568Q |
probably damaging |
Het |
| Foxd4 |
T |
C |
19: 24,877,826 (GRCm39) |
T125A |
probably damaging |
Het |
| Fthl17b |
C |
T |
X: 8,829,043 (GRCm39) |
R9Q |
possibly damaging |
Het |
| Fthl17b |
C |
T |
X: 8,829,047 (GRCm39) |
V8M |
possibly damaging |
Het |
| Gcsam |
C |
A |
16: 45,440,240 (GRCm39) |
H94Q |
probably damaging |
Het |
| Ginm1 |
T |
A |
10: 7,649,844 (GRCm39) |
I150F |
probably damaging |
Het |
| H2bw2 |
G |
A |
X: 135,828,471 (GRCm39) |
R120K |
unknown |
Het |
| Hk2 |
G |
A |
6: 82,720,326 (GRCm39) |
A205V |
probably damaging |
Het |
| Il3ra |
A |
T |
14: 14,349,345 (GRCm38) |
H147L |
probably benign |
Het |
| Map3k6 |
T |
A |
4: 132,975,707 (GRCm39) |
S732T |
probably benign |
Het |
| Masp2 |
A |
G |
4: 148,690,178 (GRCm39) |
E229G |
probably benign |
Het |
| Mccc2 |
A |
G |
13: 100,108,285 (GRCm39) |
|
probably null |
Het |
| Mia3 |
A |
G |
1: 183,108,508 (GRCm39) |
V359A |
|
Het |
| Mob1a |
A |
T |
6: 83,309,492 (GRCm39) |
T80S |
probably benign |
Het |
| Msantd2 |
G |
A |
9: 37,434,590 (GRCm39) |
G478S |
probably damaging |
Het |
| Mtf1 |
A |
G |
4: 124,718,974 (GRCm39) |
E329G |
probably null |
Het |
| Myh9 |
T |
A |
15: 77,648,065 (GRCm39) |
K1804* |
probably null |
Het |
| Ndst3 |
A |
G |
3: 123,465,313 (GRCm39) |
W220R |
probably damaging |
Het |
| Nln |
A |
G |
13: 104,173,478 (GRCm39) |
L576P |
probably damaging |
Het |
| Nlrc4 |
A |
G |
17: 74,753,483 (GRCm39) |
M300T |
probably benign |
Het |
| Obscn |
G |
T |
11: 59,020,403 (GRCm39) |
D880E |
possibly damaging |
Het |
| Oprd1 |
T |
C |
4: 131,844,763 (GRCm39) |
T82A |
probably damaging |
Het |
| Or2n1d |
T |
A |
17: 38,646,183 (GRCm39) |
I45N |
probably damaging |
Het |
| Or4f60 |
A |
C |
2: 111,902,445 (GRCm39) |
V161G |
probably benign |
Het |
| Orc3 |
A |
G |
4: 34,595,136 (GRCm39) |
C278R |
probably damaging |
Het |
| Pde4d |
T |
A |
13: 109,769,322 (GRCm39) |
|
probably null |
Het |
| Pms1 |
T |
C |
1: 53,236,231 (GRCm39) |
E683G |
probably benign |
Het |
| Prkaa2 |
T |
C |
4: 104,932,740 (GRCm39) |
Q36R |
probably benign |
Het |
| Psg22 |
A |
G |
7: 18,456,891 (GRCm39) |
E258G |
probably damaging |
Het |
| Ptprf |
T |
C |
4: 118,069,369 (GRCm39) |
D1566G |
probably damaging |
Het |
| Rfwd3 |
T |
A |
8: 111,999,701 (GRCm39) |
Y759F |
probably benign |
Het |
| Ripor2 |
A |
G |
13: 24,880,533 (GRCm39) |
D411G |
probably damaging |
Het |
| Ryr2 |
A |
C |
13: 11,571,634 (GRCm39) |
|
probably null |
Het |
| Sdr42e1 |
T |
C |
8: 118,389,490 (GRCm39) |
T384A |
probably benign |
Het |
| Sec1 |
A |
T |
7: 45,334,149 (GRCm39) |
|
probably null |
Het |
| Sec16a |
A |
T |
2: 26,311,409 (GRCm39) |
F616I |
|
Het |
| Sipa1l2 |
T |
C |
8: 126,208,845 (GRCm39) |
D521G |
possibly damaging |
Het |
| Smc1b |
T |
A |
15: 84,981,743 (GRCm39) |
Q759L |
probably benign |
Het |
| Snph |
A |
T |
2: 151,442,263 (GRCm39) |
S57R |
probably damaging |
Het |
| Sqor |
A |
T |
2: 122,629,450 (GRCm39) |
T103S |
probably benign |
Het |
| Srbd1 |
A |
G |
17: 86,443,749 (GRCm39) |
V159A |
probably benign |
Het |
| Srsf2 |
A |
T |
11: 116,743,727 (GRCm39) |
V10E |
probably damaging |
Het |
| Swap70 |
T |
A |
7: 109,863,316 (GRCm39) |
|
probably null |
Het |
| Synm |
A |
C |
7: 67,382,954 (GRCm39) |
*675G |
probably null |
Het |
| Tek |
A |
G |
4: 94,699,582 (GRCm39) |
E320G |
probably benign |
Het |
| Tenm3 |
T |
C |
8: 48,689,218 (GRCm39) |
D2123G |
probably damaging |
Het |
| Tmod4 |
A |
G |
3: 95,033,174 (GRCm39) |
K56R |
possibly damaging |
Het |
| Top3b |
G |
A |
16: 16,695,714 (GRCm39) |
|
probably benign |
Het |
| Tssc4 |
G |
T |
7: 142,624,425 (GRCm39) |
E244D |
possibly damaging |
Het |
| Twnk |
G |
A |
19: 44,999,003 (GRCm39) |
|
probably null |
Het |
| Ube4a |
A |
C |
9: 44,868,011 (GRCm39) |
I45S |
probably benign |
Het |
| Unc79 |
A |
T |
12: 103,055,017 (GRCm39) |
M954L |
possibly damaging |
Het |
| Vcpip1 |
A |
T |
1: 9,816,540 (GRCm39) |
D614E |
probably benign |
Het |
| Vmn1r45 |
T |
A |
6: 89,910,035 (GRCm39) |
I312L |
probably benign |
Het |
| Vmn1r77 |
A |
G |
7: 11,775,611 (GRCm39) |
Y129C |
probably damaging |
Het |
| Zer1 |
A |
G |
2: 29,992,834 (GRCm39) |
L600P |
probably damaging |
Het |
| Zfp266 |
T |
C |
9: 20,412,232 (GRCm39) |
T114A |
probably benign |
Het |
| Zrsr2-ps1 |
T |
C |
11: 22,924,662 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Prdm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00530:Prdm2
|
APN |
4 |
142,860,329 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00843:Prdm2
|
APN |
4 |
142,860,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01419:Prdm2
|
APN |
4 |
142,860,218 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01662:Prdm2
|
APN |
4 |
142,860,138 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01892:Prdm2
|
APN |
4 |
142,860,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02104:Prdm2
|
APN |
4 |
142,859,997 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02208:Prdm2
|
APN |
4 |
142,862,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02260:Prdm2
|
APN |
4 |
142,861,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02479:Prdm2
|
APN |
4 |
142,861,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Prdm2
|
APN |
4 |
142,858,542 (GRCm39) |
missense |
probably benign |
|
|
IGL02972:Prdm2
|
APN |
4 |
142,858,736 (GRCm39) |
missense |
probably benign |
|
|
IGL03038:Prdm2
|
APN |
4 |
142,860,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Prdm2
|
APN |
4 |
142,861,658 (GRCm39) |
missense |
probably benign |
0.07 |
|
G1patch:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
PIT4677001:Prdm2
|
UTSW |
4 |
142,861,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0088:Prdm2
|
UTSW |
4 |
142,861,524 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0153:Prdm2
|
UTSW |
4 |
142,860,338 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0320:Prdm2
|
UTSW |
4 |
142,905,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0384:Prdm2
|
UTSW |
4 |
142,862,258 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0400:Prdm2
|
UTSW |
4 |
142,838,240 (GRCm39) |
missense |
probably benign |
|
|
R0658:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0850:Prdm2
|
UTSW |
4 |
142,858,773 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1118:Prdm2
|
UTSW |
4 |
142,858,953 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1355:Prdm2
|
UTSW |
4 |
142,858,533 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1519:Prdm2
|
UTSW |
4 |
142,862,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Prdm2
|
UTSW |
4 |
142,861,032 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1987:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2006:Prdm2
|
UTSW |
4 |
142,858,447 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2008:Prdm2
|
UTSW |
4 |
142,861,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Prdm2
|
UTSW |
4 |
142,859,334 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R2112:Prdm2
|
UTSW |
4 |
142,858,506 (GRCm39) |
missense |
probably benign |
|
|
R2221:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2223:Prdm2
|
UTSW |
4 |
142,861,469 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2426:Prdm2
|
UTSW |
4 |
142,838,320 (GRCm39) |
nonsense |
probably null |
|
|
R2430:Prdm2
|
UTSW |
4 |
142,859,733 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2484:Prdm2
|
UTSW |
4 |
142,861,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Prdm2
|
UTSW |
4 |
142,860,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Prdm2
|
UTSW |
4 |
142,858,385 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4209:Prdm2
|
UTSW |
4 |
142,861,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4411:Prdm2
|
UTSW |
4 |
142,860,240 (GRCm39) |
missense |
probably benign |
0.18 |
|
R4647:Prdm2
|
UTSW |
4 |
142,859,525 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4898:Prdm2
|
UTSW |
4 |
142,860,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Prdm2
|
UTSW |
4 |
142,905,937 (GRCm39) |
nonsense |
probably null |
|
|
R5181:Prdm2
|
UTSW |
4 |
142,861,536 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5513:Prdm2
|
UTSW |
4 |
142,862,463 (GRCm39) |
small deletion |
probably benign |
|
|
R5539:Prdm2
|
UTSW |
4 |
142,859,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5563:Prdm2
|
UTSW |
4 |
142,861,200 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5618:Prdm2
|
UTSW |
4 |
142,860,107 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5900:Prdm2
|
UTSW |
4 |
142,861,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5990:Prdm2
|
UTSW |
4 |
142,896,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6148:Prdm2
|
UTSW |
4 |
142,859,477 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6166:Prdm2
|
UTSW |
4 |
142,861,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6223:Prdm2
|
UTSW |
4 |
142,868,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6530:Prdm2
|
UTSW |
4 |
142,860,617 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6631:Prdm2
|
UTSW |
4 |
142,861,454 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6725:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6847:Prdm2
|
UTSW |
4 |
142,859,520 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7193:Prdm2
|
UTSW |
4 |
142,907,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Prdm2
|
UTSW |
4 |
142,862,391 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7292:Prdm2
|
UTSW |
4 |
142,859,471 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7748:Prdm2
|
UTSW |
4 |
142,862,459 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7885:Prdm2
|
UTSW |
4 |
142,861,140 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7936:Prdm2
|
UTSW |
4 |
142,862,434 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7976:Prdm2
|
UTSW |
4 |
142,859,812 (GRCm39) |
nonsense |
probably null |
|
|
R8124:Prdm2
|
UTSW |
4 |
142,861,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Prdm2
|
UTSW |
4 |
142,859,303 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8156:Prdm2
|
UTSW |
4 |
142,861,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8178:Prdm2
|
UTSW |
4 |
142,859,018 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8235:Prdm2
|
UTSW |
4 |
142,859,037 (GRCm39) |
nonsense |
probably null |
|
|
R8404:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8498:Prdm2
|
UTSW |
4 |
142,907,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8502:Prdm2
|
UTSW |
4 |
142,861,584 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8688:Prdm2
|
UTSW |
4 |
142,838,310 (GRCm39) |
missense |
probably benign |
|
|
R8732:Prdm2
|
UTSW |
4 |
142,862,580 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Prdm2
|
UTSW |
4 |
142,860,017 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8874:Prdm2
|
UTSW |
4 |
142,859,785 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8887:Prdm2
|
UTSW |
4 |
142,860,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9119:Prdm2
|
UTSW |
4 |
142,858,449 (GRCm39) |
nonsense |
probably null |
|
|
R9139:Prdm2
|
UTSW |
4 |
142,858,752 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9165:Prdm2
|
UTSW |
4 |
142,858,674 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9342:Prdm2
|
UTSW |
4 |
142,861,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9518:Prdm2
|
UTSW |
4 |
142,860,579 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9546:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Prdm2
|
UTSW |
4 |
142,861,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9680:Prdm2
|
UTSW |
4 |
142,859,079 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9730:Prdm2
|
UTSW |
4 |
142,858,659 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
X0017:Prdm2
|
UTSW |
4 |
142,861,277 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGCAGCTTCAAACTACACAG -3'
(R):5'- CCCCTGGAGGACTTTAGTTG -3'
Sequencing Primer
(F):5'- GGCAGCTTCAAACTACACAGACATG -3'
(R):5'- CCCCTGGAGGACTTTAGTTGATTTG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation