Incidental Mutation 'R7426:Cfap65'
| ID |
576031 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cfap65
|
| Ensembl Gene |
ENSMUSG00000047021 |
| Gene Name |
cilia and flagella associated protein 65 |
| Synonyms |
Ccdc108, B230363K08Rik |
| MMRRC Submission |
045504-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.720)
|
| Stock # |
R7426 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
74941230-74974758 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 74959585 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 855
(V855A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000092440
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094844]
|
| AlphaFold |
Q3V0B4 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000094844
AA Change: V855A
PolyPhen 2
Score 0.917 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000092440
Gene: ENSMUSG00000047021
AA Change: V855A
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
111 |
133 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
745 |
890 |
9.31e-5 |
PROSPERO |
|
internal_repeat_1
|
1167 |
1322 |
9.31e-5 |
PROSPERO |
|
low complexity region
|
1350 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1574 |
1592 |
N/A |
INTRINSIC |
|
coiled coil region
|
1687 |
1724 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
97% (114/118) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. The chicken ortholog of this gene is involved in the Rose-comb mutation, which is a large chromosome inversion, resulting in altered comb morphology and defects in sperm motility. [provided by RefSeq, Aug 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 117 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca15 |
C |
A |
7: 119,945,221 (GRCm39) |
N432K |
possibly damaging |
Het |
| Abitram |
A |
G |
4: 56,804,230 (GRCm39) |
I82V |
probably null |
Het |
| Adamtsl5 |
G |
A |
10: 80,180,693 (GRCm39) |
T123I |
probably benign |
Het |
| Aff4 |
T |
C |
11: 53,263,702 (GRCm39) |
S241P |
probably damaging |
Het |
| Agl |
A |
G |
3: 116,552,404 (GRCm39) |
L510P |
|
Het |
| Aox1 |
A |
T |
1: 58,329,142 (GRCm39) |
K196* |
probably null |
Het |
| Arhgef37 |
A |
G |
18: 61,637,456 (GRCm39) |
L402P |
probably damaging |
Het |
| Arid4b |
T |
C |
13: 14,355,891 (GRCm39) |
|
probably null |
Het |
| Atp5pb |
A |
G |
3: 105,851,118 (GRCm39) |
V193A |
probably benign |
Het |
| Atp8b3 |
A |
G |
10: 80,365,463 (GRCm39) |
|
probably null |
Het |
| Baz2a |
G |
T |
10: 127,951,947 (GRCm39) |
R555L |
probably damaging |
Het |
| Casp4 |
G |
T |
9: 5,321,345 (GRCm39) |
S32I |
possibly damaging |
Het |
| Cd300lb |
A |
G |
11: 114,819,128 (GRCm39) |
V167A |
probably damaging |
Het |
| Cdc42bpg |
C |
T |
19: 6,368,428 (GRCm39) |
T1042I |
probably damaging |
Het |
| Ceacam20 |
T |
C |
7: 19,704,159 (GRCm39) |
F70S |
probably damaging |
Het |
| Cep162 |
C |
T |
9: 87,074,819 (GRCm39) |
V1388I |
probably damaging |
Het |
| Chil3 |
G |
T |
3: 106,063,022 (GRCm39) |
D189E |
probably benign |
Het |
| Cln3 |
A |
G |
7: 126,180,912 (GRCm39) |
I43T |
probably benign |
Het |
| Cntnap5a |
A |
G |
1: 116,370,110 (GRCm39) |
Q909R |
probably benign |
Het |
| Ctsd |
C |
A |
7: 141,937,278 (GRCm39) |
A77S |
probably damaging |
Het |
| Dnah12 |
T |
A |
14: 26,445,781 (GRCm39) |
S781T |
probably benign |
Het |
| Dnah17 |
T |
A |
11: 117,981,543 (GRCm39) |
Q1716L |
probably null |
Het |
| Dock3 |
C |
A |
9: 106,772,782 (GRCm39) |
M490I |
probably benign |
Het |
| Erg |
T |
C |
16: 95,260,015 (GRCm39) |
|
probably null |
Het |
| Farp2 |
A |
T |
1: 93,548,950 (GRCm39) |
M1019L |
possibly damaging |
Het |
| Fcgbp |
A |
G |
7: 27,785,949 (GRCm39) |
K462R |
probably benign |
Het |
| Fn1 |
A |
T |
1: 71,688,384 (GRCm39) |
N173K |
probably damaging |
Het |
| Fsip2 |
A |
T |
2: 82,810,441 (GRCm39) |
L2253F |
probably damaging |
Het |
| Gabrd |
C |
T |
4: 155,469,970 (GRCm39) |
R413H |
possibly damaging |
Het |
| Galnt5 |
A |
T |
2: 57,907,151 (GRCm39) |
D538V |
probably damaging |
Het |
| Gje1 |
T |
A |
10: 14,592,223 (GRCm39) |
L186F |
probably damaging |
Het |
| Gm16686 |
A |
T |
4: 88,673,563 (GRCm39) |
C89S |
unknown |
Het |
| Gna15 |
G |
T |
10: 81,338,831 (GRCm39) |
A336E |
probably benign |
Het |
| Golga4 |
C |
T |
9: 118,388,563 (GRCm39) |
S1895L |
probably benign |
Het |
| Gon4l |
A |
T |
3: 88,814,829 (GRCm39) |
M1933L |
probably benign |
Het |
| Gpr183 |
T |
C |
14: 122,192,156 (GRCm39) |
S122G |
possibly damaging |
Het |
| Gtf2h4 |
G |
A |
17: 35,980,250 (GRCm39) |
T348I |
probably damaging |
Het |
| Hace1 |
T |
C |
10: 45,481,636 (GRCm39) |
Y120H |
probably damaging |
Het |
| Hivep2 |
C |
T |
10: 14,007,061 (GRCm39) |
H1220Y |
possibly damaging |
Het |
| Hmx2 |
T |
C |
7: 131,156,232 (GRCm39) |
F66S |
probably benign |
Het |
| Hoxd12 |
A |
T |
2: 74,505,569 (GRCm39) |
S47C |
possibly damaging |
Het |
| Hp |
C |
A |
8: 110,301,832 (GRCm39) |
|
probably null |
Het |
| Idh3a |
T |
A |
9: 54,508,492 (GRCm39) |
D355E |
probably benign |
Het |
| Itga2b |
A |
T |
11: 102,347,120 (GRCm39) |
M921K |
probably benign |
Het |
| Jcad |
A |
G |
18: 4,675,529 (GRCm39) |
D1097G |
probably benign |
Het |
| Kdm5b |
A |
T |
1: 134,523,571 (GRCm39) |
T249S |
probably benign |
Het |
| Klhl11 |
G |
T |
11: 100,355,178 (GRCm39) |
H214Q |
probably benign |
Het |
| L3hypdh |
A |
T |
12: 72,131,705 (GRCm39) |
Y76N |
probably damaging |
Het |
| Lama4 |
G |
T |
10: 38,921,751 (GRCm39) |
R424L |
possibly damaging |
Het |
| Lepr |
A |
G |
4: 101,602,853 (GRCm39) |
I214V |
probably benign |
Het |
| Lipc |
G |
T |
9: 70,709,450 (GRCm39) |
N432K |
probably benign |
Het |
| Lipm |
C |
T |
19: 34,093,598 (GRCm39) |
A216V |
possibly damaging |
Het |
| Lrrc23 |
A |
G |
6: 124,756,088 (GRCm39) |
S2P |
unknown |
Het |
| Lyst |
T |
A |
13: 13,812,109 (GRCm39) |
D840E |
probably benign |
Het |
| Mmp23 |
T |
A |
4: 155,736,041 (GRCm39) |
T204S |
probably damaging |
Het |
| Mms19 |
T |
C |
19: 41,936,717 (GRCm39) |
T785A |
probably benign |
Het |
| Mov10 |
A |
T |
3: 104,707,368 (GRCm39) |
|
probably null |
Het |
| Mtf2 |
A |
G |
5: 108,248,836 (GRCm39) |
T383A |
probably benign |
Het |
| Myo5c |
G |
A |
9: 75,158,809 (GRCm39) |
|
probably null |
Het |
| Nfxl1 |
A |
T |
5: 72,681,517 (GRCm39) |
C671* |
probably null |
Het |
| Npepps |
A |
G |
11: 97,103,982 (GRCm39) |
V813A |
probably benign |
Het |
| Nrn1 |
C |
A |
13: 36,910,825 (GRCm39) |
W69L |
probably damaging |
Het |
| Oprd1 |
A |
C |
4: 131,841,378 (GRCm39) |
D193E |
probably benign |
Het |
| Or2ag1b |
T |
A |
7: 106,288,417 (GRCm39) |
I174F |
possibly damaging |
Het |
| Or52p1 |
C |
T |
7: 104,267,059 (GRCm39) |
H58Y |
probably damaging |
Het |
| Or55b3 |
A |
T |
7: 102,126,883 (GRCm39) |
Y65N |
probably damaging |
Het |
| Or56b2j |
T |
A |
7: 104,352,796 (GRCm39) |
D7E |
probably benign |
Het |
| Or6c202 |
A |
G |
10: 128,996,620 (GRCm39) |
Y78H |
possibly damaging |
Het |
| Or6c209 |
T |
C |
10: 129,483,027 (GRCm39) |
I10T |
probably damaging |
Het |
| Or6k6 |
A |
C |
1: 173,944,753 (GRCm39) |
F276L |
probably benign |
Het |
| Pcdhac1 |
G |
T |
18: 37,225,550 (GRCm39) |
V788L |
probably benign |
Het |
| Pcdhb11 |
G |
A |
18: 37,556,313 (GRCm39) |
V548M |
probably damaging |
Het |
| Pde4c |
A |
T |
8: 71,201,621 (GRCm39) |
E517V |
possibly damaging |
Het |
| Pdzd7 |
T |
C |
19: 45,022,086 (GRCm39) |
R521G |
possibly damaging |
Het |
| Pik3c2a |
T |
A |
7: 115,972,089 (GRCm39) |
K780N |
probably damaging |
Het |
| Plb1 |
T |
G |
5: 32,478,591 (GRCm39) |
|
probably null |
Het |
| Plcb4 |
T |
A |
2: 135,842,139 (GRCm39) |
L1041Q |
probably benign |
Het |
| Pnpla6 |
G |
A |
8: 3,566,540 (GRCm39) |
|
probably null |
Het |
| Ppat |
A |
T |
5: 77,063,826 (GRCm39) |
N441K |
probably damaging |
Het |
| Ppp1r1b |
G |
A |
11: 98,246,305 (GRCm39) |
A132T |
probably damaging |
Het |
| Prl2c2 |
A |
C |
13: 13,172,065 (GRCm39) |
|
probably null |
Het |
| Prr14 |
T |
C |
7: 127,074,458 (GRCm39) |
I330T |
probably benign |
Het |
| Pycr1 |
T |
C |
11: 120,533,749 (GRCm39) |
D36G |
probably benign |
Het |
| Rabep2 |
T |
A |
7: 126,037,891 (GRCm39) |
I221N |
probably damaging |
Het |
| Rad23b |
A |
G |
4: 55,370,469 (GRCm39) |
D165G |
probably benign |
Het |
| Reln |
G |
A |
5: 22,176,951 (GRCm39) |
T1905I |
probably damaging |
Het |
| Ripor2 |
T |
C |
13: 24,878,188 (GRCm39) |
V321A |
probably benign |
Het |
| Rnf43 |
A |
G |
11: 87,622,678 (GRCm39) |
D466G |
probably benign |
Het |
| Rpl6 |
A |
T |
5: 121,343,655 (GRCm39) |
R63W |
possibly damaging |
Het |
| S100a14 |
A |
G |
3: 90,435,511 (GRCm39) |
T102A |
probably benign |
Het |
| Samd11 |
C |
A |
4: 156,333,857 (GRCm39) |
V195L |
probably benign |
Het |
| Scaper |
G |
A |
9: 55,669,561 (GRCm39) |
Q372* |
probably null |
Het |
| Sec14l5 |
G |
T |
16: 4,998,739 (GRCm39) |
C593F |
probably damaging |
Het |
| Sema6d |
T |
C |
2: 124,496,078 (GRCm39) |
Y41H |
probably damaging |
Het |
| Serac1 |
G |
A |
17: 6,119,589 (GRCm39) |
R114W |
probably damaging |
Het |
| Slc12a4 |
T |
C |
8: 106,677,468 (GRCm39) |
E388G |
probably benign |
Het |
| Smarcd3 |
T |
C |
5: 24,800,810 (GRCm39) |
T164A |
probably benign |
Het |
| Smtn |
C |
A |
11: 3,480,249 (GRCm39) |
R324L |
probably benign |
Het |
| Spata31d1c |
C |
T |
13: 65,183,175 (GRCm39) |
P239L |
probably benign |
Het |
| Srcap |
T |
C |
7: 127,137,689 (GRCm39) |
V1013A |
possibly damaging |
Het |
| Sv2b |
T |
C |
7: 74,773,812 (GRCm39) |
N553S |
probably damaging |
Het |
| Tex35 |
T |
A |
1: 156,932,656 (GRCm39) |
N52I |
probably damaging |
Het |
| Ticrr |
T |
C |
7: 79,343,734 (GRCm39) |
S1200P |
probably benign |
Het |
| Tmem19 |
A |
G |
10: 115,183,604 (GRCm39) |
L125P |
probably damaging |
Het |
| Trio |
A |
G |
15: 27,856,193 (GRCm39) |
V666A |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,747,627 (GRCm39) |
D4474G |
probably benign |
Het |
| Usp43 |
A |
T |
11: 67,783,842 (GRCm39) |
S368T |
possibly damaging |
Het |
| Vmn2r72 |
T |
A |
7: 85,400,348 (GRCm39) |
M234L |
probably benign |
Het |
| Wdr93 |
T |
A |
7: 79,427,055 (GRCm39) |
|
probably null |
Het |
| Wrap73 |
T |
A |
4: 154,240,584 (GRCm39) |
W359R |
probably damaging |
Het |
| Ywhah |
A |
G |
5: 33,183,985 (GRCm39) |
I63V |
probably benign |
Het |
| Zbtb7b |
G |
T |
3: 89,288,366 (GRCm39) |
P151T |
probably damaging |
Het |
| Zfp318 |
A |
G |
17: 46,710,995 (GRCm39) |
N906S |
probably damaging |
Het |
| Zfp423 |
C |
A |
8: 88,507,341 (GRCm39) |
C1001F |
probably damaging |
Het |
| Zmym1 |
A |
G |
4: 126,943,191 (GRCm39) |
I399T |
possibly damaging |
Het |
| Zmynd15 |
G |
A |
11: 70,353,014 (GRCm39) |
G296D |
probably benign |
Het |
| Znfx1 |
T |
A |
2: 166,890,475 (GRCm39) |
I670F |
probably damaging |
Het |
|
| Other mutations in Cfap65 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01107:Cfap65
|
APN |
1 |
74,958,342 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01526:Cfap65
|
APN |
1 |
74,950,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01716:Cfap65
|
APN |
1 |
74,966,353 (GRCm39) |
missense |
probably benign |
|
|
IGL01780:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL01993:Cfap65
|
APN |
1 |
74,959,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02164:Cfap65
|
APN |
1 |
74,967,304 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02350:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL02357:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL02576:Cfap65
|
APN |
1 |
74,942,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02756:Cfap65
|
APN |
1 |
74,944,239 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02792:Cfap65
|
APN |
1 |
74,966,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02874:Cfap65
|
APN |
1 |
74,950,267 (GRCm39) |
nonsense |
probably null |
|
|
IGL03101:Cfap65
|
APN |
1 |
74,967,592 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL03348:Cfap65
|
APN |
1 |
74,966,778 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03396:Cfap65
|
APN |
1 |
74,943,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4131001:Cfap65
|
UTSW |
1 |
74,967,501 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0077:Cfap65
|
UTSW |
1 |
74,971,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0227:Cfap65
|
UTSW |
1 |
74,971,117 (GRCm39) |
nonsense |
probably null |
|
|
R0281:Cfap65
|
UTSW |
1 |
74,966,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0312:Cfap65
|
UTSW |
1 |
74,943,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,968,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,968,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0347:Cfap65
|
UTSW |
1 |
74,965,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0359:Cfap65
|
UTSW |
1 |
74,959,760 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0361:Cfap65
|
UTSW |
1 |
74,964,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Cfap65
|
UTSW |
1 |
74,956,043 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0549:Cfap65
|
UTSW |
1 |
74,957,603 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0646:Cfap65
|
UTSW |
1 |
74,941,328 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0734:Cfap65
|
UTSW |
1 |
74,958,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0763:Cfap65
|
UTSW |
1 |
74,943,841 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0990:Cfap65
|
UTSW |
1 |
74,960,678 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R1079:Cfap65
|
UTSW |
1 |
74,944,872 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1079:Cfap65
|
UTSW |
1 |
74,941,606 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1083:Cfap65
|
UTSW |
1 |
74,957,663 (GRCm39) |
splice site |
probably benign |
|
|
R1159:Cfap65
|
UTSW |
1 |
74,968,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1282:Cfap65
|
UTSW |
1 |
74,964,263 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Cfap65
|
UTSW |
1 |
74,956,334 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1796:Cfap65
|
UTSW |
1 |
74,958,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1950:Cfap65
|
UTSW |
1 |
74,946,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2079:Cfap65
|
UTSW |
1 |
74,956,358 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2132:Cfap65
|
UTSW |
1 |
74,946,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2136:Cfap65
|
UTSW |
1 |
74,956,432 (GRCm39) |
frame shift |
probably null |
|
|
R2219:Cfap65
|
UTSW |
1 |
74,943,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2220:Cfap65
|
UTSW |
1 |
74,943,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2291:Cfap65
|
UTSW |
1 |
74,965,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2417:Cfap65
|
UTSW |
1 |
74,966,345 (GRCm39) |
small insertion |
probably benign |
|
|
R3114:Cfap65
|
UTSW |
1 |
74,966,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4202:Cfap65
|
UTSW |
1 |
74,959,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4214:Cfap65
|
UTSW |
1 |
74,966,840 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4254:Cfap65
|
UTSW |
1 |
74,942,517 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4547:Cfap65
|
UTSW |
1 |
74,946,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4548:Cfap65
|
UTSW |
1 |
74,946,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4588:Cfap65
|
UTSW |
1 |
74,943,215 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4657:Cfap65
|
UTSW |
1 |
74,964,513 (GRCm39) |
intron |
probably benign |
|
|
R4701:Cfap65
|
UTSW |
1 |
74,958,067 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4755:Cfap65
|
UTSW |
1 |
74,967,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4820:Cfap65
|
UTSW |
1 |
74,966,791 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4831:Cfap65
|
UTSW |
1 |
74,956,454 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4866:Cfap65
|
UTSW |
1 |
74,964,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4869:Cfap65
|
UTSW |
1 |
74,958,420 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4881:Cfap65
|
UTSW |
1 |
74,946,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4884:Cfap65
|
UTSW |
1 |
74,942,283 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R4950:Cfap65
|
UTSW |
1 |
74,945,495 (GRCm39) |
nonsense |
probably null |
|
|
R5074:Cfap65
|
UTSW |
1 |
74,962,137 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5083:Cfap65
|
UTSW |
1 |
74,945,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5164:Cfap65
|
UTSW |
1 |
74,965,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5268:Cfap65
|
UTSW |
1 |
74,964,061 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5333:Cfap65
|
UTSW |
1 |
74,942,334 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5417:Cfap65
|
UTSW |
1 |
74,964,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5582:Cfap65
|
UTSW |
1 |
74,946,677 (GRCm39) |
intron |
probably benign |
|
|
R5669:Cfap65
|
UTSW |
1 |
74,964,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6010:Cfap65
|
UTSW |
1 |
74,962,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Cfap65
|
UTSW |
1 |
74,959,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6112:Cfap65
|
UTSW |
1 |
74,942,298 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6425:Cfap65
|
UTSW |
1 |
74,966,868 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6677:Cfap65
|
UTSW |
1 |
74,943,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6693:Cfap65
|
UTSW |
1 |
74,956,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6838:Cfap65
|
UTSW |
1 |
74,971,180 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6861:Cfap65
|
UTSW |
1 |
74,964,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6958:Cfap65
|
UTSW |
1 |
74,971,058 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R7134:Cfap65
|
UTSW |
1 |
74,965,792 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7320:Cfap65
|
UTSW |
1 |
74,965,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7340:Cfap65
|
UTSW |
1 |
74,960,742 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7529:Cfap65
|
UTSW |
1 |
74,965,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7634:Cfap65
|
UTSW |
1 |
74,941,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7654:Cfap65
|
UTSW |
1 |
74,972,303 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7704:Cfap65
|
UTSW |
1 |
74,967,527 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7727:Cfap65
|
UTSW |
1 |
74,965,784 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7895:Cfap65
|
UTSW |
1 |
74,972,321 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8215:Cfap65
|
UTSW |
1 |
74,949,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8344:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8345:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8413:Cfap65
|
UTSW |
1 |
74,956,328 (GRCm39) |
nonsense |
probably null |
|
|
R8431:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8432:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8528:Cfap65
|
UTSW |
1 |
74,945,096 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8809:Cfap65
|
UTSW |
1 |
74,942,382 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8996:Cfap65
|
UTSW |
1 |
74,941,347 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9020:Cfap65
|
UTSW |
1 |
74,959,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9043:Cfap65
|
UTSW |
1 |
74,943,847 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9127:Cfap65
|
UTSW |
1 |
74,958,510 (GRCm39) |
splice site |
probably benign |
|
|
R9187:Cfap65
|
UTSW |
1 |
74,956,517 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9210:Cfap65
|
UTSW |
1 |
74,959,567 (GRCm39) |
missense |
probably benign |
|
|
R9212:Cfap65
|
UTSW |
1 |
74,959,567 (GRCm39) |
missense |
probably benign |
|
|
R9273:Cfap65
|
UTSW |
1 |
74,960,769 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9454:Cfap65
|
UTSW |
1 |
74,944,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9514:Cfap65
|
UTSW |
1 |
74,945,468 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9595:Cfap65
|
UTSW |
1 |
74,946,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9721:Cfap65
|
UTSW |
1 |
74,958,501 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9742:Cfap65
|
UTSW |
1 |
74,943,840 (GRCm39) |
missense |
probably benign |
0.08 |
|
RF009:Cfap65
|
UTSW |
1 |
74,944,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Cfap65
|
UTSW |
1 |
74,949,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTTGACTAAAGCCCACTTGCAG -3'
(R):5'- CAAGAGGTCATGGCATTGTCC -3'
Sequencing Primer
(F):5'- TAAAGCCCACTTGCAGGCTAGG -3'
(R):5'- TCCTCTGGCTCAGGAAGTG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation