Mutagenetix > Incidental Mutation

Incidental Mutation 'R7426:Fcgbp'

576069

Institutional Source

Beutler Lab

Gene Symbol

Fcgbp

Ensembl Gene

ENSMUSG00000047730

Gene Name

Fc fragment of IgG binding protein

Synonyms

A430096B05Rik

MMRRC Submission

045504-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7426 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

27770661-27820287 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 27785949 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Arginine at position 462 (K462R)

Ref Sequence

ENSEMBL: ENSMUSP00000075945 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000076648] [ENSMUST00000138392]

AlphaFold

E9Q0B5

Predicted Effect

probably benign
Transcript: ENSMUST00000076648
AA Change: K462R

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000075945
Gene: ENSMUSG00000047730
AA Change: K462R

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	1.2e-12	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	6.85e-35	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	4.7e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.7e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	5e-12	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000138392
AA Change: K462R

PolyPhen 2 Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)

SMART Domains

Protein: ENSMUSP00000114271
Gene: ENSMUSG00000047730
AA Change: K462R

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	8.4e-13	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	7.99e-36	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	3.3e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.9e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	1e-11	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Meta Mutation Damage Score

0.0846

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.0%

Validation Efficiency

97% (114/118)

Allele List at MGI

Other mutations in this stock

Total: 117 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca15	C	A	7: 119,945,221 (GRCm39)	N432K	possibly damaging	Het
Abitram	A	G	4: 56,804,230 (GRCm39)	I82V	probably null	Het
Adamtsl5	G	A	10: 80,180,693 (GRCm39)	T123I	probably benign	Het
Aff4	T	C	11: 53,263,702 (GRCm39)	S241P	probably damaging	Het
Agl	A	G	3: 116,552,404 (GRCm39)	L510P		Het
Aox1	A	T	1: 58,329,142 (GRCm39)	K196*	probably null	Het
Arhgef37	A	G	18: 61,637,456 (GRCm39)	L402P	probably damaging	Het
Arid4b	T	C	13: 14,355,891 (GRCm39)		probably null	Het
Atp5pb	A	G	3: 105,851,118 (GRCm39)	V193A	probably benign	Het
Atp8b3	A	G	10: 80,365,463 (GRCm39)		probably null	Het
Baz2a	G	T	10: 127,951,947 (GRCm39)	R555L	probably damaging	Het
Casp4	G	T	9: 5,321,345 (GRCm39)	S32I	possibly damaging	Het
Cd300lb	A	G	11: 114,819,128 (GRCm39)	V167A	probably damaging	Het
Cdc42bpg	C	T	19: 6,368,428 (GRCm39)	T1042I	probably damaging	Het
Ceacam20	T	C	7: 19,704,159 (GRCm39)	F70S	probably damaging	Het
Cep162	C	T	9: 87,074,819 (GRCm39)	V1388I	probably damaging	Het
Cfap65	A	G	1: 74,959,585 (GRCm39)	V855A	possibly damaging	Het
Chil3	G	T	3: 106,063,022 (GRCm39)	D189E	probably benign	Het
Cln3	A	G	7: 126,180,912 (GRCm39)	I43T	probably benign	Het
Cntnap5a	A	G	1: 116,370,110 (GRCm39)	Q909R	probably benign	Het
Ctsd	C	A	7: 141,937,278 (GRCm39)	A77S	probably damaging	Het
Dnah12	T	A	14: 26,445,781 (GRCm39)	S781T	probably benign	Het
Dnah17	T	A	11: 117,981,543 (GRCm39)	Q1716L	probably null	Het
Dock3	C	A	9: 106,772,782 (GRCm39)	M490I	probably benign	Het
Erg	T	C	16: 95,260,015 (GRCm39)		probably null	Het
Farp2	A	T	1: 93,548,950 (GRCm39)	M1019L	possibly damaging	Het
Fn1	A	T	1: 71,688,384 (GRCm39)	N173K	probably damaging	Het
Fsip2	A	T	2: 82,810,441 (GRCm39)	L2253F	probably damaging	Het
Gabrd	C	T	4: 155,469,970 (GRCm39)	R413H	possibly damaging	Het
Galnt5	A	T	2: 57,907,151 (GRCm39)	D538V	probably damaging	Het
Gje1	T	A	10: 14,592,223 (GRCm39)	L186F	probably damaging	Het
Gm16686	A	T	4: 88,673,563 (GRCm39)	C89S	unknown	Het
Gna15	G	T	10: 81,338,831 (GRCm39)	A336E	probably benign	Het
Golga4	C	T	9: 118,388,563 (GRCm39)	S1895L	probably benign	Het
Gon4l	A	T	3: 88,814,829 (GRCm39)	M1933L	probably benign	Het
Gpr183	T	C	14: 122,192,156 (GRCm39)	S122G	possibly damaging	Het
Gtf2h4	G	A	17: 35,980,250 (GRCm39)	T348I	probably damaging	Het
Hace1	T	C	10: 45,481,636 (GRCm39)	Y120H	probably damaging	Het
Hivep2	C	T	10: 14,007,061 (GRCm39)	H1220Y	possibly damaging	Het
Hmx2	T	C	7: 131,156,232 (GRCm39)	F66S	probably benign	Het
Hoxd12	A	T	2: 74,505,569 (GRCm39)	S47C	possibly damaging	Het
Hp	C	A	8: 110,301,832 (GRCm39)		probably null	Het
Idh3a	T	A	9: 54,508,492 (GRCm39)	D355E	probably benign	Het
Itga2b	A	T	11: 102,347,120 (GRCm39)	M921K	probably benign	Het
Jcad	A	G	18: 4,675,529 (GRCm39)	D1097G	probably benign	Het
Kdm5b	A	T	1: 134,523,571 (GRCm39)	T249S	probably benign	Het
Klhl11	G	T	11: 100,355,178 (GRCm39)	H214Q	probably benign	Het
L3hypdh	A	T	12: 72,131,705 (GRCm39)	Y76N	probably damaging	Het
Lama4	G	T	10: 38,921,751 (GRCm39)	R424L	possibly damaging	Het
Lepr	A	G	4: 101,602,853 (GRCm39)	I214V	probably benign	Het
Lipc	G	T	9: 70,709,450 (GRCm39)	N432K	probably benign	Het
Lipm	C	T	19: 34,093,598 (GRCm39)	A216V	possibly damaging	Het
Lrrc23	A	G	6: 124,756,088 (GRCm39)	S2P	unknown	Het
Lyst	T	A	13: 13,812,109 (GRCm39)	D840E	probably benign	Het
Mmp23	T	A	4: 155,736,041 (GRCm39)	T204S	probably damaging	Het
Mms19	T	C	19: 41,936,717 (GRCm39)	T785A	probably benign	Het
Mov10	A	T	3: 104,707,368 (GRCm39)		probably null	Het
Mtf2	A	G	5: 108,248,836 (GRCm39)	T383A	probably benign	Het
Myo5c	G	A	9: 75,158,809 (GRCm39)		probably null	Het
Nfxl1	A	T	5: 72,681,517 (GRCm39)	C671*	probably null	Het
Npepps	A	G	11: 97,103,982 (GRCm39)	V813A	probably benign	Het
Nrn1	C	A	13: 36,910,825 (GRCm39)	W69L	probably damaging	Het
Oprd1	A	C	4: 131,841,378 (GRCm39)	D193E	probably benign	Het
Or2ag1b	T	A	7: 106,288,417 (GRCm39)	I174F	possibly damaging	Het
Or52p1	C	T	7: 104,267,059 (GRCm39)	H58Y	probably damaging	Het
Or55b3	A	T	7: 102,126,883 (GRCm39)	Y65N	probably damaging	Het
Or56b2j	T	A	7: 104,352,796 (GRCm39)	D7E	probably benign	Het
Or6c202	A	G	10: 128,996,620 (GRCm39)	Y78H	possibly damaging	Het
Or6c209	T	C	10: 129,483,027 (GRCm39)	I10T	probably damaging	Het
Or6k6	A	C	1: 173,944,753 (GRCm39)	F276L	probably benign	Het
Pcdhac1	G	T	18: 37,225,550 (GRCm39)	V788L	probably benign	Het
Pcdhb11	G	A	18: 37,556,313 (GRCm39)	V548M	probably damaging	Het
Pde4c	A	T	8: 71,201,621 (GRCm39)	E517V	possibly damaging	Het
Pdzd7	T	C	19: 45,022,086 (GRCm39)	R521G	possibly damaging	Het
Pik3c2a	T	A	7: 115,972,089 (GRCm39)	K780N	probably damaging	Het
Plb1	T	G	5: 32,478,591 (GRCm39)		probably null	Het
Plcb4	T	A	2: 135,842,139 (GRCm39)	L1041Q	probably benign	Het
Pnpla6	G	A	8: 3,566,540 (GRCm39)		probably null	Het
Ppat	A	T	5: 77,063,826 (GRCm39)	N441K	probably damaging	Het
Ppp1r1b	G	A	11: 98,246,305 (GRCm39)	A132T	probably damaging	Het
Prl2c2	A	C	13: 13,172,065 (GRCm39)		probably null	Het
Prr14	T	C	7: 127,074,458 (GRCm39)	I330T	probably benign	Het
Pycr1	T	C	11: 120,533,749 (GRCm39)	D36G	probably benign	Het
Rabep2	T	A	7: 126,037,891 (GRCm39)	I221N	probably damaging	Het
Rad23b	A	G	4: 55,370,469 (GRCm39)	D165G	probably benign	Het
Reln	G	A	5: 22,176,951 (GRCm39)	T1905I	probably damaging	Het
Ripor2	T	C	13: 24,878,188 (GRCm39)	V321A	probably benign	Het
Rnf43	A	G	11: 87,622,678 (GRCm39)	D466G	probably benign	Het
Rpl6	A	T	5: 121,343,655 (GRCm39)	R63W	possibly damaging	Het
S100a14	A	G	3: 90,435,511 (GRCm39)	T102A	probably benign	Het
Samd11	C	A	4: 156,333,857 (GRCm39)	V195L	probably benign	Het
Scaper	G	A	9: 55,669,561 (GRCm39)	Q372*	probably null	Het
Sec14l5	G	T	16: 4,998,739 (GRCm39)	C593F	probably damaging	Het
Sema6d	T	C	2: 124,496,078 (GRCm39)	Y41H	probably damaging	Het
Serac1	G	A	17: 6,119,589 (GRCm39)	R114W	probably damaging	Het
Slc12a4	T	C	8: 106,677,468 (GRCm39)	E388G	probably benign	Het
Smarcd3	T	C	5: 24,800,810 (GRCm39)	T164A	probably benign	Het
Smtn	C	A	11: 3,480,249 (GRCm39)	R324L	probably benign	Het
Spata31d1c	C	T	13: 65,183,175 (GRCm39)	P239L	probably benign	Het
Srcap	T	C	7: 127,137,689 (GRCm39)	V1013A	possibly damaging	Het
Sv2b	T	C	7: 74,773,812 (GRCm39)	N553S	probably damaging	Het
Tex35	T	A	1: 156,932,656 (GRCm39)	N52I	probably damaging	Het
Ticrr	T	C	7: 79,343,734 (GRCm39)	S1200P	probably benign	Het
Tmem19	A	G	10: 115,183,604 (GRCm39)	L125P	probably damaging	Het
Trio	A	G	15: 27,856,193 (GRCm39)	V666A	probably benign	Het
Ttn	T	C	2: 76,747,627 (GRCm39)	D4474G	probably benign	Het
Usp43	A	T	11: 67,783,842 (GRCm39)	S368T	possibly damaging	Het
Vmn2r72	T	A	7: 85,400,348 (GRCm39)	M234L	probably benign	Het
Wdr93	T	A	7: 79,427,055 (GRCm39)		probably null	Het
Wrap73	T	A	4: 154,240,584 (GRCm39)	W359R	probably damaging	Het
Ywhah	A	G	5: 33,183,985 (GRCm39)	I63V	probably benign	Het
Zbtb7b	G	T	3: 89,288,366 (GRCm39)	P151T	probably damaging	Het
Zfp318	A	G	17: 46,710,995 (GRCm39)	N906S	probably damaging	Het
Zfp423	C	A	8: 88,507,341 (GRCm39)	C1001F	probably damaging	Het
Zmym1	A	G	4: 126,943,191 (GRCm39)	I399T	possibly damaging	Het
Zmynd15	G	A	11: 70,353,014 (GRCm39)	G296D	probably benign	Het
Znfx1	T	A	2: 166,890,475 (GRCm39)	I670F	probably damaging	Het

Other mutations in Fcgbp

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00309:Fcgbp	APN	7	27,784,555 (GRCm39)	missense	probably damaging	1.00
IGL00331:Fcgbp	APN	7	27,800,966 (GRCm39)	splice site	probably benign
IGL00335:Fcgbp	APN	7	27,785,560 (GRCm39)	missense	possibly damaging	0.90
IGL00470:Fcgbp	APN	7	27,774,511 (GRCm39)	nonsense	probably null
IGL00491:Fcgbp	APN	7	27,792,827 (GRCm39)	missense	probably damaging	1.00
IGL00498:Fcgbp	APN	7	27,791,222 (GRCm39)	missense	probably damaging	1.00
IGL01296:Fcgbp	APN	7	27,789,072 (GRCm39)	missense	probably benign	0.15
IGL01582:Fcgbp	APN	7	27,793,067 (GRCm39)	missense	probably benign	0.19
IGL01929:Fcgbp	APN	7	27,803,388 (GRCm39)	missense	probably damaging	1.00
IGL02024:Fcgbp	APN	7	27,805,799 (GRCm39)	missense	probably damaging	1.00
IGL02027:Fcgbp	APN	7	27,774,629 (GRCm39)	missense	probably damaging	1.00
IGL02140:Fcgbp	APN	7	27,791,379 (GRCm39)	missense	probably damaging	1.00
IGL02162:Fcgbp	APN	7	27,774,660 (GRCm39)	missense	probably damaging	1.00
IGL02345:Fcgbp	APN	7	27,771,068 (GRCm39)	splice site	probably benign
IGL02377:Fcgbp	APN	7	27,806,395 (GRCm39)	missense	possibly damaging	0.67
IGL02389:Fcgbp	APN	7	27,774,596 (GRCm39)	missense	probably damaging	1.00
IGL02423:Fcgbp	APN	7	27,789,378 (GRCm39)	missense	probably benign	0.02
IGL02523:Fcgbp	APN	7	27,804,157 (GRCm39)	missense	possibly damaging	0.89
IGL02561:Fcgbp	APN	7	27,800,599 (GRCm39)	intron	probably benign
IGL02631:Fcgbp	APN	7	27,784,723 (GRCm39)	missense	probably damaging	1.00
IGL02716:Fcgbp	APN	7	27,800,859 (GRCm39)	missense	probably damaging	0.98
IGL02836:Fcgbp	APN	7	27,816,783 (GRCm39)	missense	possibly damaging	0.91
IGL02957:Fcgbp	APN	7	27,791,272 (GRCm39)	nonsense	probably null
IGL02971:Fcgbp	APN	7	27,800,898 (GRCm39)	missense	probably damaging	1.00
IGL03284:Fcgbp	APN	7	27,784,857 (GRCm39)	missense	possibly damaging	0.93
IGL03379:Fcgbp	APN	7	27,789,342 (GRCm39)	missense	possibly damaging	0.76
bilge	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R6548_fcgbp_365	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
swill	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
G1citation:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
IGL02796:Fcgbp	UTSW	7	27,800,576 (GRCm39)	intron	probably benign
PIT4486001:Fcgbp	UTSW	7	27,774,698 (GRCm39)	missense	possibly damaging	0.52
R0277:Fcgbp	UTSW	7	27,784,918 (GRCm39)	critical splice donor site	probably null
R0387:Fcgbp	UTSW	7	27,790,879 (GRCm39)	splice site	probably benign
R0586:Fcgbp	UTSW	7	27,789,138 (GRCm39)	missense	probably damaging	1.00
R0981:Fcgbp	UTSW	7	27,784,535 (GRCm39)	nonsense	probably null
R0987:Fcgbp	UTSW	7	27,793,599 (GRCm39)	missense	probably damaging	1.00
R1240:Fcgbp	UTSW	7	27,819,950 (GRCm39)	missense	probably damaging	1.00
R1394:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1395:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1438:Fcgbp	UTSW	7	27,803,158 (GRCm39)	nonsense	probably null
R1474:Fcgbp	UTSW	7	27,791,273 (GRCm39)	missense	probably benign	0.00
R1521:Fcgbp	UTSW	7	27,774,585 (GRCm39)	missense	probably benign	0.00
R1740:Fcgbp	UTSW	7	27,800,674 (GRCm39)	missense	possibly damaging	0.87
R1750:Fcgbp	UTSW	7	27,792,868 (GRCm39)	nonsense	probably null
R1772:Fcgbp	UTSW	7	27,804,600 (GRCm39)	missense	possibly damaging	0.90
R1804:Fcgbp	UTSW	7	27,785,564 (GRCm39)	missense	probably benign
R1808:Fcgbp	UTSW	7	27,784,515 (GRCm39)	missense	probably benign	0.04
R1819:Fcgbp	UTSW	7	27,784,708 (GRCm39)	missense	probably benign	0.00
R1934:Fcgbp	UTSW	7	27,806,518 (GRCm39)	missense	probably damaging	1.00
R1972:Fcgbp	UTSW	7	27,793,617 (GRCm39)	missense	probably benign	0.11
R2051:Fcgbp	UTSW	7	27,819,785 (GRCm39)	missense	probably damaging	0.97
R2072:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2074:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2124:Fcgbp	UTSW	7	27,791,444 (GRCm39)	missense	probably benign	0.03
R2155:Fcgbp	UTSW	7	27,806,628 (GRCm39)	missense	probably benign	0.00
R3015:Fcgbp	UTSW	7	27,774,838 (GRCm39)	splice site	probably benign
R3037:Fcgbp	UTSW	7	27,802,127 (GRCm39)	missense	possibly damaging	0.62
R3151:Fcgbp	UTSW	7	27,816,665 (GRCm39)	missense	probably damaging	1.00
R3176:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3177:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3276:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3277:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3623:Fcgbp	UTSW	7	27,800,701 (GRCm39)	missense	probably damaging	1.00
R3730:Fcgbp	UTSW	7	27,784,882 (GRCm39)	missense	possibly damaging	0.82
R3935:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R3936:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R4041:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	probably benign	0.01
R4056:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4057:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4705:Fcgbp	UTSW	7	27,806,721 (GRCm39)	missense	probably benign	0.44
R4708:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4710:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4779:Fcgbp	UTSW	7	27,794,362 (GRCm39)	missense	probably damaging	1.00
R4820:Fcgbp	UTSW	7	27,813,383 (GRCm39)	missense	probably damaging	1.00
R4863:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.33
R4926:Fcgbp	UTSW	7	27,785,660 (GRCm39)	missense	probably damaging	0.99
R4947:Fcgbp	UTSW	7	27,789,237 (GRCm39)	missense	probably benign	0.00
R4979:Fcgbp	UTSW	7	27,816,995 (GRCm39)	missense	probably benign	0.06
R5002:Fcgbp	UTSW	7	27,785,528 (GRCm39)	splice site	probably null
R5219:Fcgbp	UTSW	7	27,803,510 (GRCm39)	missense	probably damaging	1.00
R5241:Fcgbp	UTSW	7	27,784,624 (GRCm39)	missense	probably damaging	1.00
R5301:Fcgbp	UTSW	7	27,793,099 (GRCm39)	missense	possibly damaging	0.93
R5306:Fcgbp	UTSW	7	27,791,243 (GRCm39)	missense	probably damaging	1.00
R5335:Fcgbp	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
R5399:Fcgbp	UTSW	7	27,804,480 (GRCm39)	missense	probably benign	0.05
R5418:Fcgbp	UTSW	7	27,784,738 (GRCm39)	missense	probably damaging	1.00
R5527:Fcgbp	UTSW	7	27,793,060 (GRCm39)	missense	probably benign
R5583:Fcgbp	UTSW	7	27,791,004 (GRCm39)	missense	probably damaging	1.00
R5698:Fcgbp	UTSW	7	27,791,447 (GRCm39)	missense	possibly damaging	0.95
R5780:Fcgbp	UTSW	7	27,784,643 (GRCm39)	missense	probably benign	0.02
R5813:Fcgbp	UTSW	7	27,800,919 (GRCm39)	missense	possibly damaging	0.64
R5910:Fcgbp	UTSW	7	27,784,928 (GRCm39)	splice site	probably benign
R5936:Fcgbp	UTSW	7	27,786,117 (GRCm39)	missense	probably damaging	0.98
R5992:Fcgbp	UTSW	7	27,819,959 (GRCm39)	missense	probably benign	0.05
R6091:Fcgbp	UTSW	7	27,804,390 (GRCm39)	missense	possibly damaging	0.90
R6372:Fcgbp	UTSW	7	27,806,433 (GRCm39)	missense	probably damaging	1.00
R6488:Fcgbp	UTSW	7	27,792,963 (GRCm39)	missense	probably damaging	0.96
R6548:Fcgbp	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
R6553:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6585:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6695:Fcgbp	UTSW	7	27,785,695 (GRCm39)	nonsense	probably null
R6711:Fcgbp	UTSW	7	27,789,098 (GRCm39)	missense	probably damaging	0.99
R6803:Fcgbp	UTSW	7	27,802,637 (GRCm39)	missense	probably benign	0.00
R6822:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
R6907:Fcgbp	UTSW	7	27,784,443 (GRCm39)	missense	probably damaging	1.00
R6912:Fcgbp	UTSW	7	27,789,129 (GRCm39)	missense	probably benign	0.15
R6924:Fcgbp	UTSW	7	27,793,248 (GRCm39)	missense	probably benign
R6943:Fcgbp	UTSW	7	27,791,477 (GRCm39)	missense	probably benign	0.22
R7060:Fcgbp	UTSW	7	27,791,358 (GRCm39)	missense	probably benign	0.20
R7103:Fcgbp	UTSW	7	27,784,387 (GRCm39)	missense	probably benign	0.00
R7208:Fcgbp	UTSW	7	27,803,446 (GRCm39)	missense	probably benign	0.01
R7291:Fcgbp	UTSW	7	27,800,817 (GRCm39)	missense	probably benign	0.00
R7301:Fcgbp	UTSW	7	27,792,861 (GRCm39)	missense	possibly damaging	0.65
R7404:Fcgbp	UTSW	7	27,800,932 (GRCm39)	missense	probably damaging	1.00
R7459:Fcgbp	UTSW	7	27,806,710 (GRCm39)	missense	possibly damaging	0.65
R7475:Fcgbp	UTSW	7	27,802,401 (GRCm39)	missense	probably damaging	0.99
R7505:Fcgbp	UTSW	7	27,789,099 (GRCm39)	missense	probably damaging	0.97
R7517:Fcgbp	UTSW	7	27,784,794 (GRCm39)	missense	probably damaging	1.00
R7519:Fcgbp	UTSW	7	27,785,724 (GRCm39)	missense	probably damaging	1.00
R7524:Fcgbp	UTSW	7	27,802,391 (GRCm39)	missense	probably damaging	1.00
R7649:Fcgbp	UTSW	7	27,790,928 (GRCm39)	missense	possibly damaging	0.88
R7782:Fcgbp	UTSW	7	27,784,460 (GRCm39)	nonsense	probably null
R7820:Fcgbp	UTSW	7	27,819,784 (GRCm39)	missense	probably benign	0.01
R7831:Fcgbp	UTSW	7	27,806,404 (GRCm39)	missense	probably damaging	0.98
R7835:Fcgbp	UTSW	7	27,816,632 (GRCm39)	missense	possibly damaging	0.64
R7947:Fcgbp	UTSW	7	27,803,595 (GRCm39)	critical splice donor site	probably null
R8086:Fcgbp	UTSW	7	27,813,389 (GRCm39)	missense	probably damaging	1.00
R8137:Fcgbp	UTSW	7	27,804,496 (GRCm39)	missense	probably damaging	1.00
R8154:Fcgbp	UTSW	7	27,784,507 (GRCm39)	missense	probably benign	0.00
R8169:Fcgbp	UTSW	7	27,784,919 (GRCm39)	critical splice donor site	probably null
R8176:Fcgbp	UTSW	7	27,791,174 (GRCm39)	missense	possibly damaging	0.88
R8193:Fcgbp	UTSW	7	27,804,276 (GRCm39)	missense	probably damaging	1.00
R8313:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.00
R8350:Fcgbp	UTSW	7	27,793,614 (GRCm39)	missense	probably benign	0.02
R8382:Fcgbp	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R8393:Fcgbp	UTSW	7	27,806,815 (GRCm39)	missense	probably benign	0.18
R8438:Fcgbp	UTSW	7	27,789,231 (GRCm39)	missense	probably benign	0.25
R8489:Fcgbp	UTSW	7	27,804,435 (GRCm39)	missense	possibly damaging	0.94
R8495:Fcgbp	UTSW	7	27,785,978 (GRCm39)	missense	probably damaging	1.00
R8707:Fcgbp	UTSW	7	27,819,920 (GRCm39)	missense	probably benign	0.01
R8736:Fcgbp	UTSW	7	27,805,621 (GRCm39)	missense	probably benign	0.05
R8816:Fcgbp	UTSW	7	27,784,412 (GRCm39)	missense	probably benign	0.09
R8905:Fcgbp	UTSW	7	27,785,934 (GRCm39)	missense	probably damaging	1.00
R9031:Fcgbp	UTSW	7	27,790,908 (GRCm39)	missense	possibly damaging	0.89
R9063:Fcgbp	UTSW	7	27,791,277 (GRCm39)	missense	probably damaging	1.00
R9180:Fcgbp	UTSW	7	27,803,198 (GRCm39)	nonsense	probably null
R9262:Fcgbp	UTSW	7	27,819,952 (GRCm39)	missense	probably damaging	1.00
R9439:Fcgbp	UTSW	7	27,803,436 (GRCm39)	missense	possibly damaging	0.60
R9526:Fcgbp	UTSW	7	27,790,937 (GRCm39)	missense	probably damaging	1.00
R9603:Fcgbp	UTSW	7	27,802,563 (GRCm39)	missense	probably damaging	1.00
R9635:Fcgbp	UTSW	7	27,800,832 (GRCm39)	missense	probably benign	0.40
R9703:Fcgbp	UTSW	7	27,806,400 (GRCm39)	missense	probably damaging	0.98
R9711:Fcgbp	UTSW	7	27,793,000 (GRCm39)	missense	probably benign	0.00
R9733:Fcgbp	UTSW	7	27,803,012 (GRCm39)	missense	probably damaging	1.00
RF002:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
X0028:Fcgbp	UTSW	7	27,803,445 (GRCm39)	missense	possibly damaging	0.48
Z1186:Fcgbp	UTSW	7	27,791,072 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,785,616 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,803,309 (GRCm39)	missense	probably benign	0.09
Z1186:Fcgbp	UTSW	7	27,792,770 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GTTTGATGATGACCGATGCCG -3'
(R):5'- TGTGGAACTTACCAGCACTCTTC -3'

Sequencing Primer
(F):5'- GCAATGTGCAGAATGGC -3'
(R):5'- AGGATTCTCCCTTCGCACAG -3'

Posted On

2019-10-07