Incidental Mutation 'R7447:Ppp4r4'
| ID |
577381 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ppp4r4
|
| Ensembl Gene |
ENSMUSG00000021209 |
| Gene Name |
protein phosphatase 4, regulatory subunit 4 |
| Synonyms |
8430415E04Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.154)
|
| Stock # |
R7447 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
103498542-103580090 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 103551985 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Methionine
at position 293
(I293M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000021631
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000021631]
[ENSMUST00000187155]
[ENSMUST00000189871]
[ENSMUST00000190664]
|
| AlphaFold |
Q8C0Y0 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000021631
AA Change: I293M
PolyPhen 2
Score 0.460 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000021631
Gene: ENSMUSG00000021209
AA Change: I293M
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
55 |
577 |
6e-27 |
SMART |
|
PDB:3FGA|A
|
178 |
666 |
8e-6 |
PDB |
|
coiled coil region
|
690 |
726 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000187155
AA Change: I184M
PolyPhen 2
Score 0.460 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000140874
Gene: ENSMUSG00000021209
AA Change: I184M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HEAT
|
145 |
175 |
2.8e-3 |
PFAM |
|
low complexity region
|
484 |
495 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
617 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000189871
AA Change: I293M
PolyPhen 2
Score 0.892 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000139786
Gene: ENSMUSG00000021209
AA Change: I293M
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
95 |
577 |
7e-26 |
SMART |
|
PDB:1B3U|B
|
178 |
666 |
2e-6 |
PDB |
|
coiled coil region
|
690 |
726 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000190664
AA Change: I77M
PolyPhen 2
Score 0.617 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000140295
Gene: ENSMUSG00000021209
AA Change: I77M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:HEAT
|
38 |
68 |
5.8e-4 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The encoded protein binds protein serine/threonine phosphatase 4c in the cytoplasm. [provided by RefSeq, Jan 2017]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adck5 |
A |
T |
15: 76,479,396 (GRCm39) |
I484F |
possibly damaging |
Het |
| Ago2 |
A |
T |
15: 73,009,881 (GRCm39) |
N100K |
probably benign |
Het |
| Appl1 |
T |
A |
14: 26,681,409 (GRCm39) |
K130* |
probably null |
Het |
| Arhgap39 |
G |
A |
15: 76,649,797 (GRCm39) |
|
probably benign |
Het |
| Axdnd1 |
A |
G |
1: 156,245,802 (GRCm39) |
|
probably null |
Het |
| Camta1 |
A |
T |
4: 151,168,327 (GRCm39) |
V1332E |
probably benign |
Het |
| Cd3g |
A |
G |
9: 44,884,857 (GRCm39) |
L129P |
probably damaging |
Het |
| Cd80 |
T |
G |
16: 38,294,251 (GRCm39) |
S45A |
probably benign |
Het |
| Cdk12 |
A |
T |
11: 98,136,106 (GRCm39) |
Q1120L |
unknown |
Het |
| Clip1 |
G |
A |
5: 123,791,696 (GRCm39) |
S158F |
probably benign |
Het |
| Cntn3 |
C |
A |
6: 102,255,416 (GRCm39) |
E161* |
probably null |
Het |
| Cyp3a59 |
A |
C |
5: 146,024,215 (GRCm39) |
K67T |
probably benign |
Het |
| Dmxl1 |
T |
C |
18: 49,997,681 (GRCm39) |
L623P |
probably damaging |
Het |
| Drd3 |
T |
A |
16: 43,637,426 (GRCm39) |
Y208* |
probably null |
Het |
| Dusp10 |
A |
T |
1: 183,801,153 (GRCm39) |
M307L |
probably benign |
Het |
| Dync2li1 |
A |
T |
17: 84,955,141 (GRCm39) |
I267L |
possibly damaging |
Het |
| Dynlt2b |
T |
A |
16: 32,244,089 (GRCm39) |
V95E |
probably damaging |
Het |
| Edn3 |
C |
A |
2: 174,603,544 (GRCm39) |
C97* |
probably null |
Het |
| Ehbp1l1 |
T |
A |
19: 5,769,456 (GRCm39) |
T616S |
possibly damaging |
Het |
| Eif2a |
C |
T |
3: 58,452,963 (GRCm39) |
T246I |
probably damaging |
Het |
| Enpp5 |
G |
A |
17: 44,396,155 (GRCm39) |
G356S |
probably damaging |
Het |
| Errfi1 |
A |
G |
4: 150,951,108 (GRCm39) |
T179A |
probably damaging |
Het |
| Esyt3 |
G |
A |
9: 99,203,615 (GRCm39) |
L450F |
probably damaging |
Het |
| Evx2 |
A |
G |
2: 74,489,448 (GRCm39) |
S106P |
probably benign |
Het |
| Fam83a |
T |
G |
15: 57,873,086 (GRCm39) |
V305G |
probably benign |
Het |
| Fem1al |
T |
C |
11: 29,774,122 (GRCm39) |
D445G |
probably benign |
Het |
| Gpr171 |
T |
A |
3: 59,005,860 (GRCm39) |
|
probably null |
Het |
| Grip1 |
A |
G |
10: 119,922,871 (GRCm39) |
T1106A |
probably benign |
Het |
| Hecw1 |
A |
G |
13: 14,531,789 (GRCm39) |
Y162H |
probably damaging |
Het |
| Hephl1 |
C |
T |
9: 15,009,178 (GRCm39) |
|
probably null |
Het |
| Hsp90aa1 |
A |
G |
12: 110,658,562 (GRCm39) |
I693T |
possibly damaging |
Het |
| Ifit1bl2 |
T |
A |
19: 34,596,974 (GRCm39) |
D214V |
probably damaging |
Het |
| Igsf10 |
T |
C |
3: 59,239,222 (GRCm39) |
M320V |
probably benign |
Het |
| Kcnq2 |
A |
G |
2: 180,754,887 (GRCm39) |
L220P |
probably damaging |
Het |
| Kpna1 |
C |
A |
16: 35,850,009 (GRCm39) |
Q372K |
probably damaging |
Het |
| Lilrb4a |
T |
G |
10: 51,367,149 (GRCm39) |
|
probably null |
Het |
| Ly75 |
C |
A |
2: 60,164,818 (GRCm39) |
E787* |
probably null |
Het |
| Magi1 |
T |
G |
6: 93,722,562 (GRCm39) |
S666R |
possibly damaging |
Het |
| Mif |
C |
A |
10: 75,695,687 (GRCm39) |
A39S |
possibly damaging |
Het |
| Mob4 |
G |
A |
1: 55,170,625 (GRCm39) |
|
probably benign |
Het |
| Mtmr4 |
G |
T |
11: 87,502,727 (GRCm39) |
C927F |
probably damaging |
Het |
| Myh1 |
A |
G |
11: 67,110,006 (GRCm39) |
K1398R |
probably benign |
Het |
| Myo3a |
T |
C |
2: 22,436,464 (GRCm39) |
V873A |
probably benign |
Het |
| Naip5 |
G |
T |
13: 100,356,205 (GRCm39) |
Q1137K |
not run |
Het |
| Naip5 |
T |
C |
13: 100,356,204 (GRCm39) |
Q1137R |
probably benign |
Het |
| Nckap5l |
G |
A |
15: 99,325,357 (GRCm39) |
P382L |
probably damaging |
Het |
| Ngly1 |
T |
C |
14: 16,290,844 (GRCm38) |
I442T |
probably damaging |
Het |
| Nhsl3 |
C |
A |
4: 129,115,835 (GRCm39) |
R988L |
possibly damaging |
Het |
| Nlrp1a |
T |
C |
11: 70,983,237 (GRCm39) |
Y1243C |
probably damaging |
Het |
| Or8k53 |
T |
A |
2: 86,177,150 (GRCm39) |
H320L |
possibly damaging |
Het |
| Pcsk5 |
C |
T |
19: 17,487,600 (GRCm39) |
G1027D |
probably benign |
Het |
| Pla2g2c |
T |
A |
4: 138,458,927 (GRCm39) |
I11N |
probably benign |
Het |
| Polr3d |
A |
G |
14: 70,677,240 (GRCm39) |
I331T |
probably damaging |
Het |
| Prkce |
G |
T |
17: 86,866,687 (GRCm39) |
V516F |
probably damaging |
Het |
| Prss27 |
T |
A |
17: 24,264,683 (GRCm39) |
L282Q |
probably damaging |
Het |
| Pxdn |
A |
G |
12: 30,034,926 (GRCm39) |
Y261C |
probably damaging |
Het |
| R3hcc1l |
T |
C |
19: 42,551,101 (GRCm39) |
S33P |
probably benign |
Het |
| Rab11fip3 |
G |
C |
17: 26,287,848 (GRCm39) |
R102G |
possibly damaging |
Het |
| Rabggta |
A |
T |
14: 55,956,773 (GRCm39) |
N310K |
probably null |
Het |
| Rbbp8 |
T |
A |
18: 11,793,934 (GRCm39) |
D15E |
probably benign |
Het |
| Rbm5 |
T |
C |
9: 107,623,378 (GRCm39) |
Y486C |
probably damaging |
Het |
| Rptor |
T |
A |
11: 119,775,805 (GRCm39) |
F992Y |
probably benign |
Het |
| Slc29a2 |
T |
G |
19: 5,076,445 (GRCm39) |
L111R |
probably damaging |
Het |
| Slc39a11 |
T |
A |
11: 113,452,849 (GRCm39) |
I31L |
probably benign |
Het |
| Slc6a20a |
T |
A |
9: 123,485,289 (GRCm39) |
N311I |
possibly damaging |
Het |
| Slc8a1 |
A |
G |
17: 81,956,435 (GRCm39) |
F201S |
probably damaging |
Het |
| Smtn |
C |
A |
11: 3,480,196 (GRCm39) |
V342L |
probably benign |
Het |
| Syne2 |
A |
G |
12: 76,074,853 (GRCm39) |
T4598A |
probably benign |
Het |
| Tchp |
A |
G |
5: 114,853,716 (GRCm39) |
T267A |
probably benign |
Het |
| Tes3-ps |
A |
G |
13: 49,647,508 (GRCm39) |
E128G |
possibly damaging |
Het |
| Tigar |
C |
T |
6: 127,065,129 (GRCm39) |
G173E |
probably benign |
Het |
| Tmem171 |
T |
C |
13: 98,824,862 (GRCm39) |
N256S |
probably benign |
Het |
| Tmem204 |
A |
G |
17: 25,277,270 (GRCm39) |
I205T |
probably damaging |
Het |
| Tmem63a |
A |
G |
1: 180,785,588 (GRCm39) |
K240R |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,019,351 (GRCm39) |
T446M |
probably damaging |
Het |
| Tnxb |
A |
T |
17: 34,937,444 (GRCm39) |
N2931I |
probably damaging |
Het |
| Trrap |
G |
T |
5: 144,776,284 (GRCm39) |
R2941L |
probably damaging |
Het |
| Ttc8 |
A |
T |
12: 98,910,131 (GRCm39) |
R179S |
probably damaging |
Het |
| Ttll12 |
G |
T |
15: 83,471,176 (GRCm39) |
T234N |
probably damaging |
Het |
| Ttn |
G |
T |
2: 76,577,576 (GRCm39) |
T24439K |
probably damaging |
Het |
| Ube2z |
A |
T |
11: 95,946,736 (GRCm39) |
I246N |
possibly damaging |
Het |
| Usp15 |
A |
G |
10: 123,011,786 (GRCm39) |
Y104H |
probably damaging |
Het |
| Usp29 |
A |
C |
7: 6,964,219 (GRCm39) |
T21P |
possibly damaging |
Het |
| Usp5 |
G |
A |
6: 124,798,077 (GRCm39) |
A436V |
probably damaging |
Het |
| Utp20 |
A |
G |
10: 88,608,354 (GRCm39) |
L1561S |
probably damaging |
Het |
| Xrn1 |
A |
G |
9: 95,927,547 (GRCm39) |
M1444V |
probably benign |
Het |
| Zfp236 |
G |
T |
18: 82,651,815 (GRCm39) |
Q885K |
probably damaging |
Het |
| Zfp831 |
C |
A |
2: 174,487,896 (GRCm39) |
P857Q |
possibly damaging |
Het |
|
| Other mutations in Ppp4r4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00827:Ppp4r4
|
APN |
12 |
103,545,335 (GRCm39) |
missense |
probably benign |
|
|
IGL01388:Ppp4r4
|
APN |
12 |
103,543,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01662:Ppp4r4
|
APN |
12 |
103,569,225 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01768:Ppp4r4
|
APN |
12 |
103,547,664 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL01894:Ppp4r4
|
APN |
12 |
103,559,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01921:Ppp4r4
|
APN |
12 |
103,542,569 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
IGL01960:Ppp4r4
|
APN |
12 |
103,547,753 (GRCm39) |
splice site |
probably benign |
|
|
IGL02084:Ppp4r4
|
APN |
12 |
103,566,657 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02287:Ppp4r4
|
APN |
12 |
103,553,747 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02315:Ppp4r4
|
APN |
12 |
103,566,620 (GRCm39) |
splice site |
probably benign |
|
|
IGL03137:Ppp4r4
|
APN |
12 |
103,547,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03170:Ppp4r4
|
APN |
12 |
103,557,033 (GRCm39) |
intron |
probably benign |
|
|
cataract
|
UTSW |
12 |
103,579,074 (GRCm39) |
nonsense |
probably null |
|
|
downfall
|
UTSW |
12 |
103,559,357 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0114:Ppp4r4
|
UTSW |
12 |
103,542,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0390:Ppp4r4
|
UTSW |
12 |
103,567,619 (GRCm39) |
splice site |
probably benign |
|
|
R0403:Ppp4r4
|
UTSW |
12 |
103,550,361 (GRCm39) |
missense |
probably benign |
|
|
R0548:Ppp4r4
|
UTSW |
12 |
103,579,074 (GRCm39) |
nonsense |
probably null |
|
|
R0601:Ppp4r4
|
UTSW |
12 |
103,566,779 (GRCm39) |
splice site |
probably benign |
|
|
R0894:Ppp4r4
|
UTSW |
12 |
103,566,754 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1127:Ppp4r4
|
UTSW |
12 |
103,545,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1177:Ppp4r4
|
UTSW |
12 |
103,542,582 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1378:Ppp4r4
|
UTSW |
12 |
103,547,751 (GRCm39) |
splice site |
probably benign |
|
|
R1442:Ppp4r4
|
UTSW |
12 |
103,564,504 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1497:Ppp4r4
|
UTSW |
12 |
103,573,204 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1651:Ppp4r4
|
UTSW |
12 |
103,550,331 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1797:Ppp4r4
|
UTSW |
12 |
103,564,410 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1880:Ppp4r4
|
UTSW |
12 |
103,571,294 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R2008:Ppp4r4
|
UTSW |
12 |
103,552,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2038:Ppp4r4
|
UTSW |
12 |
103,542,539 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2404:Ppp4r4
|
UTSW |
12 |
103,547,749 (GRCm39) |
splice site |
probably null |
|
|
R2696:Ppp4r4
|
UTSW |
12 |
103,547,653 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2849:Ppp4r4
|
UTSW |
12 |
103,573,192 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2965:Ppp4r4
|
UTSW |
12 |
103,579,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3030:Ppp4r4
|
UTSW |
12 |
103,573,215 (GRCm39) |
missense |
probably benign |
|
|
R3805:Ppp4r4
|
UTSW |
12 |
103,566,625 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3862:Ppp4r4
|
UTSW |
12 |
103,562,680 (GRCm39) |
nonsense |
probably null |
|
|
R4194:Ppp4r4
|
UTSW |
12 |
103,524,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4320:Ppp4r4
|
UTSW |
12 |
103,564,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4558:Ppp4r4
|
UTSW |
12 |
103,573,192 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4783:Ppp4r4
|
UTSW |
12 |
103,557,117 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4866:Ppp4r4
|
UTSW |
12 |
103,566,706 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4903:Ppp4r4
|
UTSW |
12 |
103,557,030 (GRCm39) |
splice site |
probably null |
|
|
R5309:Ppp4r4
|
UTSW |
12 |
103,573,147 (GRCm39) |
splice site |
probably null |
|
|
R5312:Ppp4r4
|
UTSW |
12 |
103,573,147 (GRCm39) |
splice site |
probably null |
|
|
R5381:Ppp4r4
|
UTSW |
12 |
103,559,357 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5383:Ppp4r4
|
UTSW |
12 |
103,550,427 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5447:Ppp4r4
|
UTSW |
12 |
103,550,410 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5942:Ppp4r4
|
UTSW |
12 |
103,553,706 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6339:Ppp4r4
|
UTSW |
12 |
103,571,228 (GRCm39) |
nonsense |
probably null |
|
|
R6386:Ppp4r4
|
UTSW |
12 |
103,559,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6712:Ppp4r4
|
UTSW |
12 |
103,562,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6755:Ppp4r4
|
UTSW |
12 |
103,551,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6868:Ppp4r4
|
UTSW |
12 |
103,557,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6879:Ppp4r4
|
UTSW |
12 |
103,518,179 (GRCm39) |
splice site |
probably null |
|
|
R7355:Ppp4r4
|
UTSW |
12 |
103,570,841 (GRCm39) |
nonsense |
probably null |
|
|
R7397:Ppp4r4
|
UTSW |
12 |
103,579,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7576:Ppp4r4
|
UTSW |
12 |
103,562,708 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7653:Ppp4r4
|
UTSW |
12 |
103,550,404 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7683:Ppp4r4
|
UTSW |
12 |
103,553,364 (GRCm39) |
nonsense |
probably null |
|
|
R7748:Ppp4r4
|
UTSW |
12 |
103,571,320 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7831:Ppp4r4
|
UTSW |
12 |
103,557,080 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7833:Ppp4r4
|
UTSW |
12 |
103,564,407 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8238:Ppp4r4
|
UTSW |
12 |
103,557,066 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8559:Ppp4r4
|
UTSW |
12 |
103,559,420 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8674:Ppp4r4
|
UTSW |
12 |
103,562,720 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8799:Ppp4r4
|
UTSW |
12 |
103,567,623 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8847:Ppp4r4
|
UTSW |
12 |
103,562,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8968:Ppp4r4
|
UTSW |
12 |
103,566,706 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9075:Ppp4r4
|
UTSW |
12 |
103,570,290 (GRCm39) |
nonsense |
probably null |
|
|
R9106:Ppp4r4
|
UTSW |
12 |
103,570,315 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9393:Ppp4r4
|
UTSW |
12 |
103,571,296 (GRCm39) |
nonsense |
probably null |
|
|
R9508:Ppp4r4
|
UTSW |
12 |
103,542,561 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9520:Ppp4r4
|
UTSW |
12 |
103,500,378 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9636:Ppp4r4
|
UTSW |
12 |
103,564,688 (GRCm39) |
missense |
unknown |
|
|
R9641:Ppp4r4
|
UTSW |
12 |
103,567,811 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9765:Ppp4r4
|
UTSW |
12 |
103,550,346 (GRCm39) |
nonsense |
probably null |
|
|
R9766:Ppp4r4
|
UTSW |
12 |
103,562,735 (GRCm39) |
missense |
probably benign |
0.40 |
|
X0025:Ppp4r4
|
UTSW |
12 |
103,566,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTCACAGTTTCTGGTGATCTCAC -3'
(R):5'- TAAGTTCTCCTAAGGCTGCGC -3'
Sequencing Primer
(F):5'- GATCTCACCCCTTGCCTCCAG -3'
(R):5'- TAAGGCTGCGCACACTTGAG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation