Mutagenetix > Incidental Mutation

Incidental Mutation 'R7454:Hmcn1'

577956

Institutional Source

Beutler Lab

Gene Symbol

Hmcn1

Ensembl Gene

ENSMUSG00000066842

Gene Name

hemicentin 1

Synonyms

EG545370, LOC240793

MMRRC Submission

045528-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7454 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

150438275-150869186 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 150439355 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 5610 (S5610P)

Ref Sequence

ENSEMBL: ENSMUSP00000074340 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074783] [ENSMUST00000137197] [ENSMUST00000177036]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000074783
AA Change: S5610P

PolyPhen 2 Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000074340
Gene: ENSMUSG00000066842
AA Change: S5610P

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
Pfam:G2F	4869	5051	1.5e-57	PFAM
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5354	4.32e-10	SMART
low complexity region	5384	5400	N/A	INTRINSIC
low complexity region	5401	5412	N/A	INTRINSIC
EGF_CA	5431	5470	2.78e-13	SMART
EGF	5474	5516	1.44e1	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000137197
AA Change: S5493P

PolyPhen 2 Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000121500
Gene: ENSMUSG00000066842
AA Change: S5493P

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
PDB:1GL4\|A	4869	5082	3e-6	PDB
SCOP:d1gl4a1	4869	5082	3e-79	SMART
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5353	2.78e-13	SMART
EGF	5357	5399	1.44e1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000177036

SMART Domains

Protein: ENSMUSP00000134985
Gene: ENSMUSG00000066842

Domain	Start	End	E-Value	Type
EGF_CA	16	57	6.8e-8	SMART
EGF_CA	58	100	3.51e-10	SMART
EGF_CA	101	140	2.78e-13	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

100% (90/90)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(4) : Targeted(3) Gene trapped(1)

Other mutations in this stock

Total: 89 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2510002D24Rik	A	G	16: 18,655,601 (GRCm39)	E57G	possibly damaging	Het
4932414N04Rik	C	A	2: 68,518,648 (GRCm39)	T159K	unknown	Het
Adamts10	T	A	17: 33,763,979 (GRCm39)	F616L	possibly damaging	Het
Adtrp	G	A	13: 41,981,791 (GRCm39)	S26L	unknown	Het
Alpk3	A	C	7: 80,728,310 (GRCm39)	E480A	probably benign	Het
Anks6	T	C	4: 47,038,919 (GRCm39)	T529A	unknown	Het
Arl4d	A	G	11: 101,557,486 (GRCm39)	H4R	probably benign	Het
Ash1l	A	G	3: 88,891,172 (GRCm39)	H1017R	probably benign	Het
Bbs12	T	C	3: 37,375,102 (GRCm39)	S517P	possibly damaging	Het
Bcl11b	C	A	12: 107,882,467 (GRCm39)	R616L	possibly damaging	Het
Bean1	G	A	8: 104,937,658 (GRCm39)	G79D	probably damaging	Het
Bicra	C	G	7: 15,706,059 (GRCm39)	G1461R	probably benign	Het
Bptf	T	C	11: 106,935,466 (GRCm39)	T124A	probably benign	Het
Btnl4	A	T	17: 34,691,348 (GRCm39)	V312E	probably benign	Het
Ccdc7a	A	G	8: 129,670,997 (GRCm39)	M503T	unknown	Het
Celf5	T	C	10: 81,318,357 (GRCm39)	E28G	probably damaging	Het
Cilp2	G	A	8: 70,336,040 (GRCm39)	L350F	probably damaging	Het
Clec4a2	T	C	6: 123,119,411 (GRCm39)	I245T	probably damaging	Het
Ctnnal1	A	T	4: 56,844,544 (GRCm39)	V140D	probably damaging	Het
Dennd4a	A	C	9: 64,759,852 (GRCm39)	H319P	probably damaging	Het
Dlgap3	G	T	4: 127,128,852 (GRCm39)	L857F	probably null	Het
Dnah6	T	A	6: 73,189,475 (GRCm39)	T58S	probably damaging	Het
Dnah7a	T	A	1: 53,557,923 (GRCm39)	M2164L	probably benign	Het
Dspp	T	A	5: 104,323,476 (GRCm39)	H206Q	probably benign	Het
Dzip1l	G	A	9: 99,541,727 (GRCm39)	V443M	possibly damaging	Het
Erc2	A	G	14: 28,024,948 (GRCm39)	H939R	possibly damaging	Het
Fam149a	G	T	8: 45,801,583 (GRCm39)	H513N	probably benign	Het
Fam171a2	T	C	11: 102,330,543 (GRCm39)	T280A	possibly damaging	Het
Fkbp5	A	C	17: 28,634,999 (GRCm39)	V170G	probably damaging	Het
Fnbp4	ACCACCTCCACCTCCACCTCC	ACCACCTCCACCTCCACCTCCACCTCC	2: 90,608,159 (GRCm39)		probably benign	Het
Fzd2	T	C	11: 102,495,955 (GRCm39)	F133S	probably damaging	Het
Galm	A	G	17: 80,445,550 (GRCm39)	N100S	possibly damaging	Het
Gbp2b	T	A	3: 142,303,920 (GRCm39)	I5N	possibly damaging	Het
Gga2	T	C	7: 121,601,369 (GRCm39)	R245G	probably benign	Het
Gm10053	A	G	19: 24,853,264 (GRCm39)	T50A	probably benign	Het
Gm1110	T	C	9: 26,831,945 (GRCm39)	T69A	probably benign	Het
Heatr5a	T	C	12: 52,008,326 (GRCm39)	S6G	probably benign	Het
Hmgb4	A	G	4: 128,154,199 (GRCm39)	V123A	probably damaging	Het
Itgal	C	A	7: 126,926,936 (GRCm39)	Q943K	probably benign	Het
Jakmip1	C	A	5: 37,332,498 (GRCm39)	D1059E	probably damaging	Het
Jazf1	T	C	6: 52,870,929 (GRCm39)		probably null	Het
Kat6a	A	G	8: 23,425,788 (GRCm39)	E1111G	possibly damaging	Het
Kdm4b	C	A	17: 56,696,639 (GRCm39)	P452T	probably benign	Het
Krit1	T	C	5: 3,862,474 (GRCm39)	Y210H	probably damaging	Het
Krtap6-2	A	T	16: 89,216,800 (GRCm39)	Y56N	unknown	Het
Lig1	A	T	7: 13,022,647 (GRCm39)	D158V	probably damaging	Het
Lmo1	A	T	7: 108,739,873 (GRCm39)	L94Q	probably benign	Het
Lrrc30	A	T	17: 67,939,238 (GRCm39)	L114H	probably damaging	Het
Ltn1	T	C	16: 87,194,700 (GRCm39)	I1400V	probably benign	Het
Mark3	T	C	12: 111,570,961 (GRCm39)	I87T	probably damaging	Het
Mfrp	G	T	9: 44,016,480 (GRCm39)	V392F	possibly damaging	Het
Mrgprg	A	G	7: 143,318,872 (GRCm39)	L80P	probably damaging	Het
Ndufaf3	A	T	9: 108,444,125 (GRCm39)	M1K	probably null	Het
Nme7	T	A	1: 164,208,217 (GRCm39)	L295*	probably null	Het
Noct	G	T	3: 51,157,151 (GRCm39)	C163F	probably damaging	Het
Or11h4b	T	A	14: 50,918,281 (GRCm39)	Q270L	possibly damaging	Het
Or13a26	A	T	7: 140,284,547 (GRCm39)	I128F	probably damaging	Het
Or4b1	T	A	2: 89,979,763 (GRCm39)	I196F	possibly damaging	Het
Or5ak22	T	A	2: 85,229,955 (GRCm39)	K307N	probably damaging	Het
Or6c203	T	A	10: 129,010,324 (GRCm39)	T189S	probably damaging	Het
Or8g2	A	G	9: 39,821,200 (GRCm39)	I34V	probably benign	Het
Patz1	C	T	11: 3,248,297 (GRCm39)		probably benign	Het
Per3	A	G	4: 151,097,185 (GRCm39)	L780P	probably benign	Het
Pira1	T	G	7: 3,738,509 (GRCm39)	E622D	probably benign	Het
Pla2g4a	T	C	1: 149,748,441 (GRCm39)	M256V	possibly damaging	Het
Pnliprp1	A	G	19: 58,729,532 (GRCm39)	K395R	probably benign	Het
Poc5	G	T	13: 96,537,340 (GRCm39)	G242V	possibly damaging	Het
Ppfia4	A	G	1: 134,251,873 (GRCm39)	S434P	possibly damaging	Het
Prss42	A	G	9: 110,627,897 (GRCm39)	N110S	probably benign	Het
Ralgapb	T	A	2: 158,274,822 (GRCm39)	I241N	possibly damaging	Het
Rbak	A	C	5: 143,159,528 (GRCm39)	Y508*	probably null	Het
S1pr2	G	T	9: 20,878,845 (GRCm39)	R328S	possibly damaging	Het
Sap130	T	C	18: 31,783,565 (GRCm39)	M214T	probably benign	Het
Slc46a1	T	A	11: 78,357,337 (GRCm39)	V130E	probably damaging	Het
Smc4	A	T	3: 68,925,457 (GRCm39)	H343L	probably benign	Het
Tarbp1	C	A	8: 127,184,416 (GRCm39)	R500L	probably benign	Het
Tasor2	A	G	13: 3,635,332 (GRCm39)	S492P	probably benign	Het
Tgfbr3	A	T	5: 107,362,894 (GRCm39)	H39Q	probably damaging	Het
Tpp2	T	C	1: 43,993,819 (GRCm39)	S235P	probably benign	Het
Trbc2	G	T	6: 41,523,763 (GRCm39)	R33M		Het
Trim3	C	T	7: 105,268,765 (GRCm39)	R63Q	probably damaging	Het
Ttc28	T	C	5: 111,433,350 (GRCm39)	V2128A	probably benign	Het
Ttn	C	T	2: 76,556,162 (GRCm39)	R30281H	probably damaging	Het
Ttn	T	A	2: 76,774,483 (GRCm39)	Q2187L	unknown	Het
Ttyh3	T	C	5: 140,615,180 (GRCm39)	S403G	possibly damaging	Het
Vmn2r112	A	T	17: 22,822,288 (GRCm39)	D322V	probably benign	Het
Wdr38	C	T	2: 38,888,352 (GRCm39)		probably benign	Het
Xrn1	T	A	9: 95,930,411 (GRCm39)	S1543R	probably benign	Het
Zbtb8b	G	A	4: 129,326,562 (GRCm39)	T201I	possibly damaging	Het

Other mutations in Hmcn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00417:Hmcn1	APN	1	150,553,029 (GRCm39)	missense	probably benign
IGL00571:Hmcn1	APN	1	150,514,750 (GRCm39)	missense	probably benign	0.05
IGL00726:Hmcn1	APN	1	150,682,117 (GRCm39)	critical splice donor site	probably null
IGL00802:Hmcn1	APN	1	150,540,687 (GRCm39)	missense	probably benign	0.19
IGL00824:Hmcn1	APN	1	150,532,485 (GRCm39)	missense	probably damaging	1.00
IGL00834:Hmcn1	APN	1	150,506,091 (GRCm39)	missense	probably benign	0.00
IGL00843:Hmcn1	APN	1	150,486,464 (GRCm39)	missense	possibly damaging	0.95
IGL00845:Hmcn1	APN	1	150,480,757 (GRCm39)	missense	probably damaging	0.98
IGL00851:Hmcn1	APN	1	150,458,052 (GRCm39)	missense	probably benign	0.02
IGL00909:Hmcn1	APN	1	150,514,620 (GRCm39)	missense	probably benign	0.12
IGL01074:Hmcn1	APN	1	150,502,784 (GRCm39)	missense	possibly damaging	0.82
IGL01112:Hmcn1	APN	1	150,508,303 (GRCm39)	splice site	probably benign
IGL01304:Hmcn1	APN	1	150,498,675 (GRCm39)	missense	probably damaging	0.99
IGL01307:Hmcn1	APN	1	150,620,752 (GRCm39)	missense	possibly damaging	0.84
IGL01318:Hmcn1	APN	1	150,594,991 (GRCm39)	missense	probably damaging	1.00
IGL01403:Hmcn1	APN	1	150,468,848 (GRCm39)	missense	probably damaging	1.00
IGL01417:Hmcn1	APN	1	150,734,990 (GRCm39)	missense	probably damaging	1.00
IGL01503:Hmcn1	APN	1	150,480,823 (GRCm39)	missense	probably benign	0.38
IGL01509:Hmcn1	APN	1	150,485,382 (GRCm39)	missense	probably damaging	1.00
IGL01550:Hmcn1	APN	1	150,474,148 (GRCm39)	missense	probably damaging	1.00
IGL01601:Hmcn1	APN	1	150,503,164 (GRCm39)	missense	probably benign	0.01
IGL01617:Hmcn1	APN	1	150,547,783 (GRCm39)	missense	probably benign	0.05
IGL01636:Hmcn1	APN	1	150,455,984 (GRCm39)	missense	probably damaging	1.00
IGL01662:Hmcn1	APN	1	150,613,050 (GRCm39)	missense	possibly damaging	0.46
IGL01693:Hmcn1	APN	1	150,459,031 (GRCm39)	missense	probably damaging	1.00
IGL01723:Hmcn1	APN	1	150,620,711 (GRCm39)	missense	probably benign	0.01
IGL01776:Hmcn1	APN	1	150,547,789 (GRCm39)	missense	possibly damaging	0.70
IGL01783:Hmcn1	APN	1	150,491,051 (GRCm39)	missense	possibly damaging	0.60
IGL01789:Hmcn1	APN	1	150,566,352 (GRCm39)	missense	probably damaging	1.00
IGL01900:Hmcn1	APN	1	150,618,011 (GRCm39)	splice site	probably benign
IGL01906:Hmcn1	APN	1	150,543,638 (GRCm39)	missense	probably benign	0.01
IGL01947:Hmcn1	APN	1	150,608,643 (GRCm39)	missense	possibly damaging	0.93
IGL01958:Hmcn1	APN	1	150,479,622 (GRCm39)	missense	probably benign	0.01
IGL02002:Hmcn1	APN	1	150,491,049 (GRCm39)	missense	probably damaging	1.00
IGL02058:Hmcn1	APN	1	150,579,932 (GRCm39)	missense	probably benign	0.02
IGL02115:Hmcn1	APN	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
IGL02127:Hmcn1	APN	1	150,598,358 (GRCm39)	missense	probably benign
IGL02155:Hmcn1	APN	1	150,439,349 (GRCm39)	missense	probably damaging	1.00
IGL02222:Hmcn1	APN	1	150,682,152 (GRCm39)	missense	probably benign	0.05
IGL02293:Hmcn1	APN	1	150,540,666 (GRCm39)	missense	probably damaging	0.97
IGL02398:Hmcn1	APN	1	150,678,648 (GRCm39)	missense	possibly damaging	0.78
IGL02420:Hmcn1	APN	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
IGL02553:Hmcn1	APN	1	150,868,774 (GRCm39)	missense	probably benign	0.12
IGL02561:Hmcn1	APN	1	150,685,477 (GRCm39)	missense	probably benign	0.32
IGL02569:Hmcn1	APN	1	150,573,244 (GRCm39)	missense	probably benign	0.01
IGL02607:Hmcn1	APN	1	150,620,746 (GRCm39)	missense	possibly damaging	0.88
IGL02676:Hmcn1	APN	1	150,494,760 (GRCm39)	missense	probably benign	0.01
IGL02725:Hmcn1	APN	1	150,480,654 (GRCm39)	missense	possibly damaging	0.92
IGL02726:Hmcn1	APN	1	150,532,445 (GRCm39)	nonsense	probably null
IGL02735:Hmcn1	APN	1	150,522,583 (GRCm39)	missense	probably benign	0.02
IGL02737:Hmcn1	APN	1	150,439,579 (GRCm39)	missense	probably damaging	1.00
IGL02892:Hmcn1	APN	1	150,551,725 (GRCm39)	critical splice donor site	probably null
IGL02927:Hmcn1	APN	1	150,453,029 (GRCm39)	missense	probably damaging	1.00
IGL02931:Hmcn1	APN	1	150,532,958 (GRCm39)	missense	probably benign	0.37
IGL02936:Hmcn1	APN	1	150,573,273 (GRCm39)	missense	probably damaging	0.98
IGL02985:Hmcn1	APN	1	150,547,668 (GRCm39)	missense	probably damaging	1.00
IGL03027:Hmcn1	APN	1	150,684,290 (GRCm39)	missense	probably benign
IGL03195:Hmcn1	APN	1	150,678,660 (GRCm39)	missense	probably benign	0.06
IGL03217:Hmcn1	APN	1	150,619,418 (GRCm39)	missense	possibly damaging	0.58
IGL03232:Hmcn1	APN	1	150,646,103 (GRCm39)	splice site	probably benign
IGL03268:Hmcn1	APN	1	150,648,261 (GRCm39)	missense	probably damaging	1.00
IGL03271:Hmcn1	APN	1	150,474,175 (GRCm39)	missense	possibly damaging	0.92
IGL03304:Hmcn1	APN	1	150,505,982 (GRCm39)	missense	probably damaging	0.97
IGL03329:Hmcn1	APN	1	150,608,661 (GRCm39)	missense	probably damaging	1.00
IGL03339:Hmcn1	APN	1	150,577,720 (GRCm39)	missense	probably benign	0.04
IGL03368:Hmcn1	APN	1	150,539,623 (GRCm39)	missense	probably damaging	1.00
Backbone	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
Cambrian	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
chordate	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
Justamere	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
Lancelet	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
notochord	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
wippoorwill	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
BB004:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
BB014:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
IGL02991:Hmcn1	UTSW	1	150,614,409 (GRCm39)	missense	possibly damaging	0.56
P0017:Hmcn1	UTSW	1	150,596,440 (GRCm39)	missense	possibly damaging	0.49
PIT1430001:Hmcn1	UTSW	1	150,684,488 (GRCm39)	missense	probably benign	0.00
PIT4514001:Hmcn1	UTSW	1	150,545,238 (GRCm39)	missense	possibly damaging	0.93
R0006:Hmcn1	UTSW	1	150,684,427 (GRCm39)	missense	probably damaging	0.99
R0018:Hmcn1	UTSW	1	150,528,302 (GRCm39)	missense	probably benign	0.16
R0052:Hmcn1	UTSW	1	150,553,157 (GRCm39)	missense	probably damaging	1.00
R0107:Hmcn1	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
R0115:Hmcn1	UTSW	1	150,684,398 (GRCm39)	missense	possibly damaging	0.88
R0149:Hmcn1	UTSW	1	150,553,075 (GRCm39)	missense	probably benign	0.00
R0152:Hmcn1	UTSW	1	150,539,630 (GRCm39)	missense	probably benign	0.01
R0381:Hmcn1	UTSW	1	150,479,562 (GRCm39)	missense	probably damaging	1.00
R0398:Hmcn1	UTSW	1	150,674,565 (GRCm39)	missense	possibly damaging	0.83
R0414:Hmcn1	UTSW	1	150,591,573 (GRCm39)	missense	possibly damaging	0.72
R0494:Hmcn1	UTSW	1	150,608,543 (GRCm39)	splice site	probably benign
R0503:Hmcn1	UTSW	1	150,735,003 (GRCm39)	missense	probably damaging	1.00
R0504:Hmcn1	UTSW	1	150,752,170 (GRCm39)	splice site	probably benign
R0506:Hmcn1	UTSW	1	150,618,092 (GRCm39)	missense	possibly damaging	0.69
R0554:Hmcn1	UTSW	1	150,594,868 (GRCm39)	missense	probably benign	0.34
R0576:Hmcn1	UTSW	1	150,525,768 (GRCm39)	nonsense	probably null
R0599:Hmcn1	UTSW	1	150,485,552 (GRCm39)	missense	possibly damaging	0.91
R0605:Hmcn1	UTSW	1	150,533,127 (GRCm39)	critical splice donor site	probably null
R0607:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R0620:Hmcn1	UTSW	1	150,469,767 (GRCm39)	missense	probably benign	0.04
R0626:Hmcn1	UTSW	1	150,674,470 (GRCm39)	splice site	probably null
R0699:Hmcn1	UTSW	1	150,695,161 (GRCm39)	missense	probably damaging	1.00
R0765:Hmcn1	UTSW	1	150,684,538 (GRCm39)	missense	probably damaging	1.00
R0782:Hmcn1	UTSW	1	150,629,416 (GRCm39)	missense	possibly damaging	0.82
R0783:Hmcn1	UTSW	1	150,525,824 (GRCm39)	missense	probably damaging	1.00
R0841:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R0975:Hmcn1	UTSW	1	150,453,128 (GRCm39)	missense	probably benign	0.00
R1070:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1118:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1119:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1233:Hmcn1	UTSW	1	150,624,777 (GRCm39)	missense	probably benign
R1234:Hmcn1	UTSW	1	150,629,405 (GRCm39)	nonsense	probably null
R1291:Hmcn1	UTSW	1	150,623,942 (GRCm39)	missense	probably damaging	1.00
R1334:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1372:Hmcn1	UTSW	1	150,556,466 (GRCm39)	missense	probably benign	0.22
R1424:Hmcn1	UTSW	1	150,522,545 (GRCm39)	missense	probably benign	0.00
R1450:Hmcn1	UTSW	1	150,528,257 (GRCm39)	splice site	probably benign
R1458:Hmcn1	UTSW	1	150,485,451 (GRCm39)	missense	probably damaging	1.00
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1473:Hmcn1	UTSW	1	150,648,303 (GRCm39)	missense	probably benign	0.03
R1517:Hmcn1	UTSW	1	150,545,172 (GRCm39)	missense	probably damaging	1.00
R1527:Hmcn1	UTSW	1	150,649,554 (GRCm39)	missense	probably benign	0.00
R1557:Hmcn1	UTSW	1	150,610,283 (GRCm39)	missense	possibly damaging	0.86
R1576:Hmcn1	UTSW	1	150,532,992 (GRCm39)	missense	possibly damaging	0.77
R1617:Hmcn1	UTSW	1	150,620,778 (GRCm39)	missense	probably damaging	0.98
R1635:Hmcn1	UTSW	1	150,545,309 (GRCm39)	missense	probably benign	0.00
R1655:Hmcn1	UTSW	1	150,506,084 (GRCm39)	missense	probably benign	0.03
R1698:Hmcn1	UTSW	1	150,441,120 (GRCm39)	nonsense	probably null
R1710:Hmcn1	UTSW	1	150,551,735 (GRCm39)	missense	probably damaging	1.00
R1717:Hmcn1	UTSW	1	150,734,937 (GRCm39)	missense	probably damaging	1.00
R1753:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1756:Hmcn1	UTSW	1	150,474,781 (GRCm39)	missense	probably damaging	1.00
R1772:Hmcn1	UTSW	1	150,439,319 (GRCm39)	missense	probably damaging	0.99
R1793:Hmcn1	UTSW	1	150,624,834 (GRCm39)	missense	probably benign	0.01
R1794:Hmcn1	UTSW	1	150,502,903 (GRCm39)	missense	probably damaging	0.98
R1794:Hmcn1	UTSW	1	150,474,036 (GRCm39)	missense	probably benign	0.00
R1856:Hmcn1	UTSW	1	150,597,415 (GRCm39)	missense	probably benign	0.02
R1859:Hmcn1	UTSW	1	150,532,944 (GRCm39)	missense	probably damaging	1.00
R1862:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1865:Hmcn1	UTSW	1	150,479,563 (GRCm39)	missense	probably damaging	1.00
R1874:Hmcn1	UTSW	1	150,596,446 (GRCm39)	missense	probably damaging	1.00
R1880:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1881:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1886:Hmcn1	UTSW	1	150,453,046 (GRCm39)	missense	probably benign	0.02
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1899:Hmcn1	UTSW	1	150,533,202 (GRCm39)	missense	probably damaging	1.00
R1905:Hmcn1	UTSW	1	150,868,606 (GRCm39)	missense	probably damaging	1.00
R1912:Hmcn1	UTSW	1	150,480,633 (GRCm39)	missense	probably benign	0.28
R1959:Hmcn1	UTSW	1	150,525,427 (GRCm39)	missense	probably benign	0.00
R1960:Hmcn1	UTSW	1	150,553,127 (GRCm39)	missense	possibly damaging	0.72
R1960:Hmcn1	UTSW	1	150,551,742 (GRCm39)	missense	probably benign	0.00
R2001:Hmcn1	UTSW	1	150,614,364 (GRCm39)	missense	possibly damaging	0.81
R2011:Hmcn1	UTSW	1	150,553,085 (GRCm39)	missense	probably benign	0.01
R2075:Hmcn1	UTSW	1	150,453,074 (GRCm39)	missense	possibly damaging	0.86
R2136:Hmcn1	UTSW	1	150,509,410 (GRCm39)	missense	probably damaging	1.00
R2192:Hmcn1	UTSW	1	150,591,566 (GRCm39)	missense	probably damaging	0.97
R2267:Hmcn1	UTSW	1	150,474,761 (GRCm39)	missense	probably benign	0.00
R2268:Hmcn1	UTSW	1	150,500,349 (GRCm39)	splice site	probably benign
R2303:Hmcn1	UTSW	1	150,579,977 (GRCm39)	missense	probably damaging	1.00
R2330:Hmcn1	UTSW	1	150,528,429 (GRCm39)	splice site	probably benign
R2338:Hmcn1	UTSW	1	150,498,685 (GRCm39)	missense	possibly damaging	0.89
R2380:Hmcn1	UTSW	1	150,441,135 (GRCm39)	missense	probably benign	0.01
R2405:Hmcn1	UTSW	1	150,736,092 (GRCm39)	missense	probably damaging	1.00
R2443:Hmcn1	UTSW	1	150,474,783 (GRCm39)	missense	probably benign	0.01
R2496:Hmcn1	UTSW	1	150,490,972 (GRCm39)	missense	probably benign	0.01
R2504:Hmcn1	UTSW	1	150,562,618 (GRCm39)	nonsense	probably null
R2519:Hmcn1	UTSW	1	150,649,571 (GRCm39)	nonsense	probably null
R2520:Hmcn1	UTSW	1	150,619,398 (GRCm39)	missense	possibly damaging	0.72
R2679:Hmcn1	UTSW	1	150,528,326 (GRCm39)	missense	possibly damaging	0.67
R2831:Hmcn1	UTSW	1	150,506,403 (GRCm39)	critical splice donor site	probably null
R2847:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2849:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2873:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2897:Hmcn1	UTSW	1	150,678,624 (GRCm39)	missense	probably damaging	1.00
R2905:Hmcn1	UTSW	1	150,624,786 (GRCm39)	missense	probably damaging	1.00
R3498:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3499:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3724:Hmcn1	UTSW	1	150,565,269 (GRCm39)	missense	possibly damaging	0.82
R3765:Hmcn1	UTSW	1	150,620,776 (GRCm39)	missense	possibly damaging	0.72
R3778:Hmcn1	UTSW	1	150,678,575 (GRCm39)	missense	possibly damaging	0.95
R3790:Hmcn1	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
R3796:Hmcn1	UTSW	1	150,462,169 (GRCm39)	missense	probably damaging	1.00
R3811:Hmcn1	UTSW	1	150,525,328 (GRCm39)	critical splice donor site	probably null
R3825:Hmcn1	UTSW	1	150,462,716 (GRCm39)	missense	probably benign	0.28
R3890:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3891:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3892:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3918:Hmcn1	UTSW	1	150,566,361 (GRCm39)	missense	probably benign	0.00
R3964:Hmcn1	UTSW	1	150,449,320 (GRCm39)	missense	probably benign	0.00
R4005:Hmcn1	UTSW	1	150,598,204 (GRCm39)	missense	possibly damaging	0.88
R4026:Hmcn1	UTSW	1	150,598,120 (GRCm39)	missense	probably benign	0.03
R4037:Hmcn1	UTSW	1	150,648,253 (GRCm39)	missense	probably benign	0.00
R4088:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R4096:Hmcn1	UTSW	1	150,534,259 (GRCm39)	missense	probably benign	0.20
R4169:Hmcn1	UTSW	1	150,471,750 (GRCm39)	splice site	probably null
R4441:Hmcn1	UTSW	1	150,533,210 (GRCm39)	missense	probably null
R4493:Hmcn1	UTSW	1	150,577,650 (GRCm39)	missense	probably damaging	1.00
R4501:Hmcn1	UTSW	1	150,509,417 (GRCm39)	missense	probably damaging	1.00
R4535:Hmcn1	UTSW	1	150,439,531 (GRCm39)	missense	probably damaging	0.99
R4576:Hmcn1	UTSW	1	150,610,238 (GRCm39)	missense	probably benign
R4601:Hmcn1	UTSW	1	150,614,396 (GRCm39)	missense	probably damaging	0.99
R4627:Hmcn1	UTSW	1	150,471,645 (GRCm39)	missense	probably benign	0.11
R4647:Hmcn1	UTSW	1	150,551,262 (GRCm39)	critical splice donor site	probably null
R4657:Hmcn1	UTSW	1	150,500,301 (GRCm39)	missense	probably damaging	1.00
R4717:Hmcn1	UTSW	1	150,494,816 (GRCm39)	missense	probably benign	0.00
R4721:Hmcn1	UTSW	1	150,648,322 (GRCm39)	splice site	probably null
R4724:Hmcn1	UTSW	1	150,570,584 (GRCm39)	splice site	probably null
R4737:Hmcn1	UTSW	1	150,565,346 (GRCm39)	missense	possibly damaging	0.90
R4744:Hmcn1	UTSW	1	150,453,363 (GRCm39)	missense	probably damaging	1.00
R4795:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4796:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4871:Hmcn1	UTSW	1	150,468,836 (GRCm39)	missense	probably benign	0.02
R4895:Hmcn1	UTSW	1	150,553,130 (GRCm39)	missense	probably benign	0.00
R4934:Hmcn1	UTSW	1	150,598,286 (GRCm39)	missense	probably damaging	1.00
R4953:Hmcn1	UTSW	1	150,752,111 (GRCm39)	intron	probably benign
R4968:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.67
R4974:Hmcn1	UTSW	1	150,695,200 (GRCm39)	missense	probably benign	0.01
R5024:Hmcn1	UTSW	1	150,556,439 (GRCm39)	missense	possibly damaging	0.65
R5031:Hmcn1	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
R5093:Hmcn1	UTSW	1	150,613,007 (GRCm39)	missense	probably benign	0.14
R5096:Hmcn1	UTSW	1	150,486,420 (GRCm39)	missense	probably damaging	1.00
R5185:Hmcn1	UTSW	1	150,532,492 (GRCm39)	missense	probably benign	0.03
R5228:Hmcn1	UTSW	1	150,522,452 (GRCm39)	missense	probably benign	0.00
R5260:Hmcn1	UTSW	1	150,471,612 (GRCm39)	missense	possibly damaging	0.65
R5264:Hmcn1	UTSW	1	150,555,265 (GRCm39)	missense	probably benign	0.01
R5282:Hmcn1	UTSW	1	150,458,047 (GRCm39)	missense	probably damaging	1.00
R5334:Hmcn1	UTSW	1	150,631,123 (GRCm39)	missense	probably damaging	0.99
R5346:Hmcn1	UTSW	1	150,498,995 (GRCm39)	missense	probably damaging	1.00
R5423:Hmcn1	UTSW	1	150,577,723 (GRCm39)	missense	probably damaging	1.00
R5484:Hmcn1	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
R5491:Hmcn1	UTSW	1	150,485,576 (GRCm39)	splice site	probably null
R5531:Hmcn1	UTSW	1	150,619,539 (GRCm39)	missense	probably damaging	1.00
R5536:Hmcn1	UTSW	1	150,631,042 (GRCm39)	missense	probably benign	0.01
R5547:Hmcn1	UTSW	1	150,613,257 (GRCm39)	missense	possibly damaging	0.64
R5580:Hmcn1	UTSW	1	150,453,290 (GRCm39)	missense	probably benign	0.43
R5626:Hmcn1	UTSW	1	150,532,318 (GRCm39)	missense	probably damaging	1.00
R5657:Hmcn1	UTSW	1	150,534,313 (GRCm39)	missense	probably benign	0.02
R5677:Hmcn1	UTSW	1	150,485,529 (GRCm39)	missense	probably benign	0.00
R5718:Hmcn1	UTSW	1	150,566,351 (GRCm39)	nonsense	probably null
R5718:Hmcn1	UTSW	1	150,485,417 (GRCm39)	missense	probably damaging	1.00
R5723:Hmcn1	UTSW	1	150,570,600 (GRCm39)	missense	possibly damaging	0.95
R5739:Hmcn1	UTSW	1	150,634,225 (GRCm39)	splice site	probably null
R5739:Hmcn1	UTSW	1	150,684,448 (GRCm39)	missense	probably benign	0.45
R5751:Hmcn1	UTSW	1	150,449,305 (GRCm39)	missense	probably damaging	1.00
R5772:Hmcn1	UTSW	1	150,570,629 (GRCm39)	missense	possibly damaging	0.47
R5804:Hmcn1	UTSW	1	150,550,098 (GRCm39)	nonsense	probably null
R5809:Hmcn1	UTSW	1	150,525,358 (GRCm39)	missense	probably damaging	1.00
R5817:Hmcn1	UTSW	1	150,613,275 (GRCm39)	missense	possibly damaging	0.77
R5824:Hmcn1	UTSW	1	150,868,774 (GRCm39)	missense	probably benign	0.12
R5881:Hmcn1	UTSW	1	150,506,078 (GRCm39)	missense	probably damaging	0.99
R5928:Hmcn1	UTSW	1	150,474,648 (GRCm39)	missense	possibly damaging	0.64
R5929:Hmcn1	UTSW	1	150,453,047 (GRCm39)	nonsense	probably null
R5940:Hmcn1	UTSW	1	150,532,973 (GRCm39)	missense	probably benign	0.41
R5973:Hmcn1	UTSW	1	150,439,568 (GRCm39)	missense	probably damaging	1.00
R5997:Hmcn1	UTSW	1	150,579,924 (GRCm39)	missense	possibly damaging	0.74
R6027:Hmcn1	UTSW	1	150,678,646 (GRCm39)	missense	possibly damaging	0.79
R6029:Hmcn1	UTSW	1	150,508,188 (GRCm39)	missense	probably benign	0.13
R6056:Hmcn1	UTSW	1	150,539,660 (GRCm39)	missense	probably damaging	1.00
R6065:Hmcn1	UTSW	1	150,646,081 (GRCm39)	missense	probably benign	0.06
R6083:Hmcn1	UTSW	1	150,631,045 (GRCm39)	missense	probably damaging	1.00
R6083:Hmcn1	UTSW	1	150,631,044 (GRCm39)	missense	probably damaging	1.00
R6108:Hmcn1	UTSW	1	150,506,978 (GRCm39)	missense	possibly damaging	0.95
R6112:Hmcn1	UTSW	1	150,494,687 (GRCm39)	missense	probably damaging	1.00
R6140:Hmcn1	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
R6144:Hmcn1	UTSW	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
R6152:Hmcn1	UTSW	1	150,441,176 (GRCm39)	missense	probably damaging	1.00
R6174:Hmcn1	UTSW	1	150,522,535 (GRCm39)	missense	probably benign	0.06
R6185:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6187:Hmcn1	UTSW	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
R6276:Hmcn1	UTSW	1	150,614,432 (GRCm39)	missense	possibly damaging	0.69
R6278:Hmcn1	UTSW	1	150,573,170 (GRCm39)	critical splice donor site	probably null
R6427:Hmcn1	UTSW	1	150,573,227 (GRCm39)	missense	possibly damaging	0.85
R6431:Hmcn1	UTSW	1	150,620,711 (GRCm39)	missense	probably benign	0.01
R6441:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R6451:Hmcn1	UTSW	1	150,868,670 (GRCm39)	missense	probably damaging	1.00
R6478:Hmcn1	UTSW	1	150,540,535 (GRCm39)	missense	probably damaging	1.00
R6479:Hmcn1	UTSW	1	150,553,053 (GRCm39)	nonsense	probably null
R6490:Hmcn1	UTSW	1	150,459,029 (GRCm39)	missense	probably benign	0.00
R6525:Hmcn1	UTSW	1	150,573,317 (GRCm39)	missense	probably damaging	1.00
R6571:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6612:Hmcn1	UTSW	1	150,470,869 (GRCm39)	critical splice donor site	probably null
R6616:Hmcn1	UTSW	1	150,599,008 (GRCm39)	critical splice donor site	probably null
R6617:Hmcn1	UTSW	1	150,619,547 (GRCm39)	missense	probably benign	0.01
R6623:Hmcn1	UTSW	1	150,634,057 (GRCm39)	missense	probably benign
R6687:Hmcn1	UTSW	1	150,620,784 (GRCm39)	missense	probably benign	0.30
R6714:Hmcn1	UTSW	1	150,579,926 (GRCm39)	missense	probably damaging	0.97
R6751:Hmcn1	UTSW	1	150,610,269 (GRCm39)	missense	probably damaging	0.98
R6831:Hmcn1	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
R6971:Hmcn1	UTSW	1	150,868,802 (GRCm39)	start codon destroyed	probably benign	0.00
R7048:Hmcn1	UTSW	1	150,475,404 (GRCm39)	critical splice acceptor site	probably null
R7058:Hmcn1	UTSW	1	150,649,641 (GRCm39)	missense	probably benign	0.43
R7071:Hmcn1	UTSW	1	150,479,853 (GRCm39)	missense	probably damaging	1.00
R7078:Hmcn1	UTSW	1	150,736,118 (GRCm39)	missense	probably damaging	1.00
R7092:Hmcn1	UTSW	1	150,479,997 (GRCm39)	missense	probably damaging	1.00
R7120:Hmcn1	UTSW	1	150,576,292 (GRCm39)	missense	probably damaging	0.98
R7129:Hmcn1	UTSW	1	150,452,961 (GRCm39)	splice site	probably null
R7144:Hmcn1	UTSW	1	150,539,624 (GRCm39)	missense	probably damaging	1.00
R7148:Hmcn1	UTSW	1	150,562,605 (GRCm39)	missense	probably benign	0.00
R7162:Hmcn1	UTSW	1	150,624,744 (GRCm39)	missense	probably benign	0.18
R7172:Hmcn1	UTSW	1	150,629,450 (GRCm39)	missense	possibly damaging	0.92
R7193:Hmcn1	UTSW	1	150,525,331 (GRCm39)	missense	probably null	1.00
R7231:Hmcn1	UTSW	1	150,514,627 (GRCm39)	missense	probably benign	0.00
R7237:Hmcn1	UTSW	1	150,598,394 (GRCm39)	missense	probably damaging	0.98
R7258:Hmcn1	UTSW	1	150,591,574 (GRCm39)	missense	probably benign	0.12
R7286:Hmcn1	UTSW	1	150,458,088 (GRCm39)	missense	probably damaging	0.98
R7289:Hmcn1	UTSW	1	150,559,466 (GRCm39)	missense	possibly damaging	0.52
R7292:Hmcn1	UTSW	1	150,608,880 (GRCm39)	splice site	probably null
R7316:Hmcn1	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
R7327:Hmcn1	UTSW	1	150,479,565 (GRCm39)	missense	probably benign	0.01
R7328:Hmcn1	UTSW	1	150,514,617 (GRCm39)	missense	possibly damaging	0.95
R7346:Hmcn1	UTSW	1	150,559,496 (GRCm39)	missense	probably damaging	1.00
R7351:Hmcn1	UTSW	1	150,543,640 (GRCm39)	missense	probably damaging	0.98
R7354:Hmcn1	UTSW	1	150,682,196 (GRCm39)	nonsense	probably null
R7360:Hmcn1	UTSW	1	150,494,597 (GRCm39)	missense	probably damaging	1.00
R7396:Hmcn1	UTSW	1	150,439,382 (GRCm39)	missense	possibly damaging	0.83
R7398:Hmcn1	UTSW	1	150,522,421 (GRCm39)	missense	probably benign	0.00
R7400:Hmcn1	UTSW	1	150,550,181 (GRCm39)	missense	probably damaging	1.00
R7404:Hmcn1	UTSW	1	150,596,510 (GRCm39)	missense	probably benign	0.00
R7424:Hmcn1	UTSW	1	150,506,017 (GRCm39)	nonsense	probably null
R7476:Hmcn1	UTSW	1	150,456,018 (GRCm39)	missense	probably damaging	0.99
R7480:Hmcn1	UTSW	1	150,552,985 (GRCm39)	critical splice donor site	probably null
R7516:Hmcn1	UTSW	1	150,498,718 (GRCm39)	missense	probably benign	0.35
R7526:Hmcn1	UTSW	1	150,532,324 (GRCm39)	missense	probably damaging	1.00
R7531:Hmcn1	UTSW	1	150,562,531 (GRCm39)	missense	probably benign	0.06
R7555:Hmcn1	UTSW	1	150,480,625 (GRCm39)	missense	probably benign	0.40
R7564:Hmcn1	UTSW	1	150,531,586 (GRCm39)	missense	probably benign
R7588:Hmcn1	UTSW	1	150,532,885 (GRCm39)	missense	possibly damaging	0.90
R7719:Hmcn1	UTSW	1	150,441,080 (GRCm39)	missense	possibly damaging	0.95
R7720:Hmcn1	UTSW	1	150,522,460 (GRCm39)	missense	probably benign	0.00
R7722:Hmcn1	UTSW	1	150,543,631 (GRCm39)	missense	probably damaging	0.98
R7761:Hmcn1	UTSW	1	150,598,196 (GRCm39)	missense	possibly damaging	0.70
R7787:Hmcn1	UTSW	1	150,632,343 (GRCm39)	missense	probably damaging	1.00
R7803:Hmcn1	UTSW	1	150,646,030 (GRCm39)	missense	probably benign	0.32
R7862:Hmcn1	UTSW	1	150,682,172 (GRCm39)	missense	probably damaging	0.96
R7876:Hmcn1	UTSW	1	150,620,722 (GRCm39)	missense	probably benign	0.03
R7886:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.94
R7891:Hmcn1	UTSW	1	150,468,940 (GRCm39)	missense	probably damaging	1.00
R7892:Hmcn1	UTSW	1	150,540,643 (GRCm39)	missense	probably benign	0.00
R7927:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
R7941:Hmcn1	UTSW	1	150,525,835 (GRCm39)	missense	possibly damaging	0.95
R7960:Hmcn1	UTSW	1	150,531,606 (GRCm39)	missense	probably damaging	1.00
R8001:Hmcn1	UTSW	1	150,540,629 (GRCm39)	nonsense	probably null
R8015:Hmcn1	UTSW	1	150,474,062 (GRCm39)	missense	possibly damaging	0.83
R8070:Hmcn1	UTSW	1	150,525,743 (GRCm39)	nonsense	probably null
R8072:Hmcn1	UTSW	1	150,532,256 (GRCm39)	missense	possibly damaging	0.62
R8113:Hmcn1	UTSW	1	150,624,841 (GRCm39)	missense	possibly damaging	0.50
R8143:Hmcn1	UTSW	1	150,734,957 (GRCm39)	missense	probably benign	0.03
R8145:Hmcn1	UTSW	1	150,629,411 (GRCm39)	missense	probably benign	0.33
R8155:Hmcn1	UTSW	1	150,480,705 (GRCm39)	missense	probably damaging	1.00
R8165:Hmcn1	UTSW	1	150,522,409 (GRCm39)	missense	probably benign	0.09
R8179:Hmcn1	UTSW	1	150,598,265 (GRCm39)	missense	probably benign	0.19
R8193:Hmcn1	UTSW	1	150,453,228 (GRCm39)	nonsense	probably null
R8234:Hmcn1	UTSW	1	150,469,761 (GRCm39)	missense	possibly damaging	0.83
R8249:Hmcn1	UTSW	1	150,695,117 (GRCm39)	missense	probably benign	0.24
R8267:Hmcn1	UTSW	1	150,735,005 (GRCm39)	missense	probably damaging	1.00
R8312:Hmcn1	UTSW	1	150,614,515 (GRCm39)	missense	probably damaging	0.99
R8338:Hmcn1	UTSW	1	150,614,485 (GRCm39)	missense	probably benign	0.35
R8354:Hmcn1	UTSW	1	150,634,142 (GRCm39)	missense	possibly damaging	0.79
R8440:Hmcn1	UTSW	1	150,570,671 (GRCm39)	missense	probably damaging	1.00
R8473:Hmcn1	UTSW	1	150,479,551 (GRCm39)	missense	possibly damaging	0.64
R8497:Hmcn1	UTSW	1	150,455,990 (GRCm39)	missense	probably benign	0.01
R8509:Hmcn1	UTSW	1	150,449,302 (GRCm39)	nonsense	probably null
R8559:Hmcn1	UTSW	1	150,551,789 (GRCm39)	missense	probably benign	0.25
R8701:Hmcn1	UTSW	1	150,631,008 (GRCm39)	missense	probably benign	0.00
R8755:Hmcn1	UTSW	1	150,509,371 (GRCm39)	missense	probably benign	0.19
R8765:Hmcn1	UTSW	1	150,556,413 (GRCm39)	missense	probably damaging	0.98
R8782:Hmcn1	UTSW	1	150,540,636 (GRCm39)	missense	probably benign	0.08
R8794:Hmcn1	UTSW	1	150,591,469 (GRCm39)	missense	probably benign	0.00
R8803:Hmcn1	UTSW	1	150,610,248 (GRCm39)	missense	probably damaging	1.00
R8808:Hmcn1	UTSW	1	150,531,570 (GRCm39)	missense	possibly damaging	0.64
R8853:Hmcn1	UTSW	1	150,547,726 (GRCm39)	missense	probably damaging	1.00
R8877:Hmcn1	UTSW	1	150,514,659 (GRCm39)	missense	probably benign	0.00
R8881:Hmcn1	UTSW	1	150,525,723 (GRCm39)	missense	probably damaging	1.00
R8916:Hmcn1	UTSW	1	150,649,530 (GRCm39)	missense	probably damaging	1.00
R9008:Hmcn1	UTSW	1	150,630,795 (GRCm39)	intron	probably benign
R9030:Hmcn1	UTSW	1	150,692,870 (GRCm39)	missense	probably benign	0.00
R9072:Hmcn1	UTSW	1	150,565,320 (GRCm39)	missense	probably benign	0.04
R9090:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9096:Hmcn1	UTSW	1	150,532,869 (GRCm39)	missense	probably benign	0.04
R9102:Hmcn1	UTSW	1	150,573,331 (GRCm39)	missense	probably benign	0.01
R9146:Hmcn1	UTSW	1	150,474,141 (GRCm39)	missense	probably benign	0.02
R9157:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9169:Hmcn1	UTSW	1	150,506,092 (GRCm39)	missense	probably damaging	0.99
R9182:Hmcn1	UTSW	1	150,488,405 (GRCm39)	missense	probably damaging	1.00
R9182:Hmcn1	UTSW	1	150,500,337 (GRCm39)	nonsense	probably null
R9204:Hmcn1	UTSW	1	150,610,262 (GRCm39)	missense	probably benign	0.40
R9219:Hmcn1	UTSW	1	150,594,844 (GRCm39)	critical splice donor site	probably null
R9267:Hmcn1	UTSW	1	150,473,740 (GRCm39)	missense	probably benign	0.26
R9271:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9274:Hmcn1	UTSW	1	150,506,046 (GRCm39)	missense	probably benign	0.01
R9313:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9414:Hmcn1	UTSW	1	150,545,187 (GRCm39)	missense	probably damaging	1.00
R9456:Hmcn1	UTSW	1	150,506,053 (GRCm39)	nonsense	probably null
R9464:Hmcn1	UTSW	1	150,599,248 (GRCm39)	missense	possibly damaging	0.80
R9474:Hmcn1	UTSW	1	150,506,471 (GRCm39)	missense	probably damaging	1.00
R9476:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9482:Hmcn1	UTSW	1	150,610,281 (GRCm39)	missense	probably benign	0.06
R9496:Hmcn1	UTSW	1	150,579,971 (GRCm39)	missense	probably benign	0.00
R9501:Hmcn1	UTSW	1	150,470,990 (GRCm39)	missense	possibly damaging	0.67
R9510:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9529:Hmcn1	UTSW	1	150,545,175 (GRCm39)	missense	probably damaging	1.00
R9566:Hmcn1	UTSW	1	150,498,660 (GRCm39)	missense	probably benign	0.00
R9608:Hmcn1	UTSW	1	150,475,303 (GRCm39)	missense	probably damaging	1.00
R9609:Hmcn1	UTSW	1	150,555,346 (GRCm39)	missense	probably damaging	0.96
R9616:Hmcn1	UTSW	1	150,684,473 (GRCm39)	missense	probably benign	0.16
R9627:Hmcn1	UTSW	1	150,506,054 (GRCm39)	missense	probably damaging	1.00
R9668:Hmcn1	UTSW	1	150,619,492 (GRCm39)	missense	probably benign	0.02
R9686:Hmcn1	UTSW	1	150,613,356 (GRCm39)	missense	probably damaging	0.99
R9717:Hmcn1	UTSW	1	150,485,378 (GRCm39)	missense	probably damaging	1.00
R9727:Hmcn1	UTSW	1	150,674,566 (GRCm39)	missense	probably benign	0.06
R9744:Hmcn1	UTSW	1	150,623,941 (GRCm39)	missense	probably damaging	1.00
R9749:Hmcn1	UTSW	1	150,632,339 (GRCm39)	missense	possibly damaging	0.94
R9761:Hmcn1	UTSW	1	150,868,625 (GRCm39)	missense	probably damaging	0.98
R9783:Hmcn1	UTSW	1	150,598,380 (GRCm39)	missense	probably benign	0.16
R9788:Hmcn1	UTSW	1	150,528,333 (GRCm39)	missense	probably benign	0.00
R9792:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9793:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9795:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9802:Hmcn1	UTSW	1	150,684,391 (GRCm39)	missense	probably benign	0.07
RF003:Hmcn1	UTSW	1	150,500,312 (GRCm39)	missense	probably damaging	1.00
RF005:Hmcn1	UTSW	1	150,510,897 (GRCm39)	nonsense	probably null
X0022:Hmcn1	UTSW	1	150,576,281 (GRCm39)	missense	probably benign	0.04
X0027:Hmcn1	UTSW	1	150,736,127 (GRCm39)	missense	probably damaging	1.00
X0028:Hmcn1	UTSW	1	150,539,652 (GRCm39)	missense	probably damaging	1.00
Z1088:Hmcn1	UTSW	1	150,524,688 (GRCm39)	missense	probably damaging	1.00
Z1176:Hmcn1	UTSW	1	150,539,668 (GRCm39)	missense	probably benign	0.12
Z1176:Hmcn1	UTSW	1	150,531,672 (GRCm39)	missense	possibly damaging	0.65
Z1176:Hmcn1	UTSW	1	150,462,196 (GRCm39)	missense	probably null	0.92

Predicted Primers

PCR Primer
(F):5'- AGCACCATTTTCAAGTTGCC -3'
(R):5'- TCCCATTTGGAATAGCCGCC -3'

Sequencing Primer
(F):5'- GTTGCCAAGATTGCAACTGTTC -3'
(R):5'- GCCAATCAAGATTTAATCCGGCTGG -3'

Posted On

2019-10-07