Incidental Mutation 'R7454:Ltn1'
| ID |
578029 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ltn1
|
| Ensembl Gene |
ENSMUSG00000052299 |
| Gene Name |
listerin E3 ubiquitin protein ligase 1 |
| Synonyms |
Listerin, Zfp294, Rnf160, 4930528H02Rik |
| MMRRC Submission |
045528-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7454 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
87173539-87229500 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 87194700 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 1400
(I1400V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000038775
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039449]
|
| AlphaFold |
Q6A009 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000039449
AA Change: I1400V
PolyPhen 2
Score 0.033 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000038775
Gene: ENSMUSG00000052299
AA Change: I1400V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
160 |
176 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
410 |
N/A |
INTRINSIC |
|
low complexity region
|
509 |
522 |
N/A |
INTRINSIC |
|
low complexity region
|
553 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
832 |
N/A |
INTRINSIC |
|
low complexity region
|
1380 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1451 |
N/A |
INTRINSIC |
|
RING
|
1716 |
1762 |
1.05e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (90/90) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 [PubMed 19196968]).[supplied by OMIM, Nov 2010]
PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Mice homozygous for a point mutation display progressive neuron degeneration and age dependent motor deficits. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510002D24Rik |
A |
G |
16: 18,655,601 (GRCm39) |
E57G |
possibly damaging |
Het |
| 4932414N04Rik |
C |
A |
2: 68,518,648 (GRCm39) |
T159K |
unknown |
Het |
| Adamts10 |
T |
A |
17: 33,763,979 (GRCm39) |
F616L |
possibly damaging |
Het |
| Adtrp |
G |
A |
13: 41,981,791 (GRCm39) |
S26L |
unknown |
Het |
| Alpk3 |
A |
C |
7: 80,728,310 (GRCm39) |
E480A |
probably benign |
Het |
| Anks6 |
T |
C |
4: 47,038,919 (GRCm39) |
T529A |
unknown |
Het |
| Arl4d |
A |
G |
11: 101,557,486 (GRCm39) |
H4R |
probably benign |
Het |
| Ash1l |
A |
G |
3: 88,891,172 (GRCm39) |
H1017R |
probably benign |
Het |
| Bbs12 |
T |
C |
3: 37,375,102 (GRCm39) |
S517P |
possibly damaging |
Het |
| Bcl11b |
C |
A |
12: 107,882,467 (GRCm39) |
R616L |
possibly damaging |
Het |
| Bean1 |
G |
A |
8: 104,937,658 (GRCm39) |
G79D |
probably damaging |
Het |
| Bicra |
C |
G |
7: 15,706,059 (GRCm39) |
G1461R |
probably benign |
Het |
| Bptf |
T |
C |
11: 106,935,466 (GRCm39) |
T124A |
probably benign |
Het |
| Btnl4 |
A |
T |
17: 34,691,348 (GRCm39) |
V312E |
probably benign |
Het |
| Ccdc7a |
A |
G |
8: 129,670,997 (GRCm39) |
M503T |
unknown |
Het |
| Celf5 |
T |
C |
10: 81,318,357 (GRCm39) |
E28G |
probably damaging |
Het |
| Cilp2 |
G |
A |
8: 70,336,040 (GRCm39) |
L350F |
probably damaging |
Het |
| Clec4a2 |
T |
C |
6: 123,119,411 (GRCm39) |
I245T |
probably damaging |
Het |
| Ctnnal1 |
A |
T |
4: 56,844,544 (GRCm39) |
V140D |
probably damaging |
Het |
| Dennd4a |
A |
C |
9: 64,759,852 (GRCm39) |
H319P |
probably damaging |
Het |
| Dlgap3 |
G |
T |
4: 127,128,852 (GRCm39) |
L857F |
probably null |
Het |
| Dnah6 |
T |
A |
6: 73,189,475 (GRCm39) |
T58S |
probably damaging |
Het |
| Dnah7a |
T |
A |
1: 53,557,923 (GRCm39) |
M2164L |
probably benign |
Het |
| Dspp |
T |
A |
5: 104,323,476 (GRCm39) |
H206Q |
probably benign |
Het |
| Dzip1l |
G |
A |
9: 99,541,727 (GRCm39) |
V443M |
possibly damaging |
Het |
| Erc2 |
A |
G |
14: 28,024,948 (GRCm39) |
H939R |
possibly damaging |
Het |
| Fam149a |
G |
T |
8: 45,801,583 (GRCm39) |
H513N |
probably benign |
Het |
| Fam171a2 |
T |
C |
11: 102,330,543 (GRCm39) |
T280A |
possibly damaging |
Het |
| Fkbp5 |
A |
C |
17: 28,634,999 (GRCm39) |
V170G |
probably damaging |
Het |
| Fnbp4 |
ACCACCTCCACCTCCACCTCC |
ACCACCTCCACCTCCACCTCCACCTCC |
2: 90,608,159 (GRCm39) |
|
probably benign |
Het |
| Fzd2 |
T |
C |
11: 102,495,955 (GRCm39) |
F133S |
probably damaging |
Het |
| Galm |
A |
G |
17: 80,445,550 (GRCm39) |
N100S |
possibly damaging |
Het |
| Gbp2b |
T |
A |
3: 142,303,920 (GRCm39) |
I5N |
possibly damaging |
Het |
| Gga2 |
T |
C |
7: 121,601,369 (GRCm39) |
R245G |
probably benign |
Het |
| Gm10053 |
A |
G |
19: 24,853,264 (GRCm39) |
T50A |
probably benign |
Het |
| Gm1110 |
T |
C |
9: 26,831,945 (GRCm39) |
T69A |
probably benign |
Het |
| Heatr5a |
T |
C |
12: 52,008,326 (GRCm39) |
S6G |
probably benign |
Het |
| Hmcn1 |
A |
G |
1: 150,439,355 (GRCm39) |
S5610P |
probably damaging |
Het |
| Hmgb4 |
A |
G |
4: 128,154,199 (GRCm39) |
V123A |
probably damaging |
Het |
| Itgal |
C |
A |
7: 126,926,936 (GRCm39) |
Q943K |
probably benign |
Het |
| Jakmip1 |
C |
A |
5: 37,332,498 (GRCm39) |
D1059E |
probably damaging |
Het |
| Jazf1 |
T |
C |
6: 52,870,929 (GRCm39) |
|
probably null |
Het |
| Kat6a |
A |
G |
8: 23,425,788 (GRCm39) |
E1111G |
possibly damaging |
Het |
| Kdm4b |
C |
A |
17: 56,696,639 (GRCm39) |
P452T |
probably benign |
Het |
| Krit1 |
T |
C |
5: 3,862,474 (GRCm39) |
Y210H |
probably damaging |
Het |
| Krtap6-2 |
A |
T |
16: 89,216,800 (GRCm39) |
Y56N |
unknown |
Het |
| Lig1 |
A |
T |
7: 13,022,647 (GRCm39) |
D158V |
probably damaging |
Het |
| Lmo1 |
A |
T |
7: 108,739,873 (GRCm39) |
L94Q |
probably benign |
Het |
| Lrrc30 |
A |
T |
17: 67,939,238 (GRCm39) |
L114H |
probably damaging |
Het |
| Mark3 |
T |
C |
12: 111,570,961 (GRCm39) |
I87T |
probably damaging |
Het |
| Mfrp |
G |
T |
9: 44,016,480 (GRCm39) |
V392F |
possibly damaging |
Het |
| Mrgprg |
A |
G |
7: 143,318,872 (GRCm39) |
L80P |
probably damaging |
Het |
| Ndufaf3 |
A |
T |
9: 108,444,125 (GRCm39) |
M1K |
probably null |
Het |
| Nme7 |
T |
A |
1: 164,208,217 (GRCm39) |
L295* |
probably null |
Het |
| Noct |
G |
T |
3: 51,157,151 (GRCm39) |
C163F |
probably damaging |
Het |
| Or11h4b |
T |
A |
14: 50,918,281 (GRCm39) |
Q270L |
possibly damaging |
Het |
| Or13a26 |
A |
T |
7: 140,284,547 (GRCm39) |
I128F |
probably damaging |
Het |
| Or4b1 |
T |
A |
2: 89,979,763 (GRCm39) |
I196F |
possibly damaging |
Het |
| Or5ak22 |
T |
A |
2: 85,229,955 (GRCm39) |
K307N |
probably damaging |
Het |
| Or6c203 |
T |
A |
10: 129,010,324 (GRCm39) |
T189S |
probably damaging |
Het |
| Or8g2 |
A |
G |
9: 39,821,200 (GRCm39) |
I34V |
probably benign |
Het |
| Patz1 |
C |
T |
11: 3,248,297 (GRCm39) |
|
probably benign |
Het |
| Per3 |
A |
G |
4: 151,097,185 (GRCm39) |
L780P |
probably benign |
Het |
| Pira1 |
T |
G |
7: 3,738,509 (GRCm39) |
E622D |
probably benign |
Het |
| Pla2g4a |
T |
C |
1: 149,748,441 (GRCm39) |
M256V |
possibly damaging |
Het |
| Pnliprp1 |
A |
G |
19: 58,729,532 (GRCm39) |
K395R |
probably benign |
Het |
| Poc5 |
G |
T |
13: 96,537,340 (GRCm39) |
G242V |
possibly damaging |
Het |
| Ppfia4 |
A |
G |
1: 134,251,873 (GRCm39) |
S434P |
possibly damaging |
Het |
| Prss42 |
A |
G |
9: 110,627,897 (GRCm39) |
N110S |
probably benign |
Het |
| Ralgapb |
T |
A |
2: 158,274,822 (GRCm39) |
I241N |
possibly damaging |
Het |
| Rbak |
A |
C |
5: 143,159,528 (GRCm39) |
Y508* |
probably null |
Het |
| S1pr2 |
G |
T |
9: 20,878,845 (GRCm39) |
R328S |
possibly damaging |
Het |
| Sap130 |
T |
C |
18: 31,783,565 (GRCm39) |
M214T |
probably benign |
Het |
| Slc46a1 |
T |
A |
11: 78,357,337 (GRCm39) |
V130E |
probably damaging |
Het |
| Smc4 |
A |
T |
3: 68,925,457 (GRCm39) |
H343L |
probably benign |
Het |
| Tarbp1 |
C |
A |
8: 127,184,416 (GRCm39) |
R500L |
probably benign |
Het |
| Tasor2 |
A |
G |
13: 3,635,332 (GRCm39) |
S492P |
probably benign |
Het |
| Tgfbr3 |
A |
T |
5: 107,362,894 (GRCm39) |
H39Q |
probably damaging |
Het |
| Tpp2 |
T |
C |
1: 43,993,819 (GRCm39) |
S235P |
probably benign |
Het |
| Trbc2 |
G |
T |
6: 41,523,763 (GRCm39) |
R33M |
|
Het |
| Trim3 |
C |
T |
7: 105,268,765 (GRCm39) |
R63Q |
probably damaging |
Het |
| Ttc28 |
T |
C |
5: 111,433,350 (GRCm39) |
V2128A |
probably benign |
Het |
| Ttn |
C |
T |
2: 76,556,162 (GRCm39) |
R30281H |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,774,483 (GRCm39) |
Q2187L |
unknown |
Het |
| Ttyh3 |
T |
C |
5: 140,615,180 (GRCm39) |
S403G |
possibly damaging |
Het |
| Vmn2r112 |
A |
T |
17: 22,822,288 (GRCm39) |
D322V |
probably benign |
Het |
| Wdr38 |
C |
T |
2: 38,888,352 (GRCm39) |
|
probably benign |
Het |
| Xrn1 |
T |
A |
9: 95,930,411 (GRCm39) |
S1543R |
probably benign |
Het |
| Zbtb8b |
G |
A |
4: 129,326,562 (GRCm39) |
T201I |
possibly damaging |
Het |
|
| Other mutations in Ltn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00328:Ltn1
|
APN |
16 |
87,215,378 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01139:Ltn1
|
APN |
16 |
87,212,897 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01359:Ltn1
|
APN |
16 |
87,202,581 (GRCm39) |
splice site |
probably benign |
|
|
IGL01503:Ltn1
|
APN |
16 |
87,217,695 (GRCm39) |
critical splice donor site |
probably benign |
|
|
IGL01529:Ltn1
|
APN |
16 |
87,178,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02437:Ltn1
|
APN |
16 |
87,194,889 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02658:Ltn1
|
APN |
16 |
87,212,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02890:Ltn1
|
APN |
16 |
87,206,185 (GRCm39) |
splice site |
probably null |
|
|
IGL02899:Ltn1
|
APN |
16 |
87,179,547 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02902:Ltn1
|
APN |
16 |
87,176,693 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL03128:Ltn1
|
APN |
16 |
87,212,832 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03392:Ltn1
|
APN |
16 |
87,222,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03046:Ltn1
|
UTSW |
16 |
87,202,509 (GRCm39) |
missense |
probably benign |
0.10 |
|
PIT4305001:Ltn1
|
UTSW |
16 |
87,217,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4366001:Ltn1
|
UTSW |
16 |
87,177,728 (GRCm39) |
nonsense |
probably null |
|
|
R0126:Ltn1
|
UTSW |
16 |
87,222,528 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0164:Ltn1
|
UTSW |
16 |
87,202,407 (GRCm39) |
splice site |
probably benign |
|
|
R0165:Ltn1
|
UTSW |
16 |
87,202,407 (GRCm39) |
splice site |
probably benign |
|
|
R0280:Ltn1
|
UTSW |
16 |
87,194,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0565:Ltn1
|
UTSW |
16 |
87,212,898 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0733:Ltn1
|
UTSW |
16 |
87,209,395 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1034:Ltn1
|
UTSW |
16 |
87,194,025 (GRCm39) |
splice site |
probably null |
|
|
R1252:Ltn1
|
UTSW |
16 |
87,212,918 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1524:Ltn1
|
UTSW |
16 |
87,178,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1746:Ltn1
|
UTSW |
16 |
87,208,669 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1826:Ltn1
|
UTSW |
16 |
87,212,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Ltn1
|
UTSW |
16 |
87,197,034 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1839:Ltn1
|
UTSW |
16 |
87,213,152 (GRCm39) |
nonsense |
probably null |
|
|
R1860:Ltn1
|
UTSW |
16 |
87,213,231 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1997:Ltn1
|
UTSW |
16 |
87,178,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Ltn1
|
UTSW |
16 |
87,212,530 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2134:Ltn1
|
UTSW |
16 |
87,179,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2135:Ltn1
|
UTSW |
16 |
87,179,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2193:Ltn1
|
UTSW |
16 |
87,224,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2307:Ltn1
|
UTSW |
16 |
87,229,312 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2376:Ltn1
|
UTSW |
16 |
87,217,695 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3054:Ltn1
|
UTSW |
16 |
87,200,961 (GRCm39) |
missense |
probably benign |
0.32 |
|
R3404:Ltn1
|
UTSW |
16 |
87,213,103 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3405:Ltn1
|
UTSW |
16 |
87,213,103 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3618:Ltn1
|
UTSW |
16 |
87,217,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4065:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4066:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4067:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4288:Ltn1
|
UTSW |
16 |
87,194,876 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4436:Ltn1
|
UTSW |
16 |
87,202,502 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4535:Ltn1
|
UTSW |
16 |
87,223,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4581:Ltn1
|
UTSW |
16 |
87,198,912 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4669:Ltn1
|
UTSW |
16 |
87,215,375 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4715:Ltn1
|
UTSW |
16 |
87,215,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4830:Ltn1
|
UTSW |
16 |
87,176,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Ltn1
|
UTSW |
16 |
87,195,697 (GRCm39) |
nonsense |
probably null |
|
|
R4961:Ltn1
|
UTSW |
16 |
87,194,679 (GRCm39) |
missense |
probably benign |
|
|
R4992:Ltn1
|
UTSW |
16 |
87,202,475 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5073:Ltn1
|
UTSW |
16 |
87,224,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5288:Ltn1
|
UTSW |
16 |
87,212,899 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5802:Ltn1
|
UTSW |
16 |
87,212,569 (GRCm39) |
missense |
probably benign |
0.17 |
|
R5907:Ltn1
|
UTSW |
16 |
87,178,391 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6180:Ltn1
|
UTSW |
16 |
87,224,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6194:Ltn1
|
UTSW |
16 |
87,212,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6257:Ltn1
|
UTSW |
16 |
87,208,662 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6301:Ltn1
|
UTSW |
16 |
87,217,194 (GRCm39) |
missense |
probably benign |
|
|
R6481:Ltn1
|
UTSW |
16 |
87,175,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6525:Ltn1
|
UTSW |
16 |
87,217,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6958:Ltn1
|
UTSW |
16 |
87,194,679 (GRCm39) |
missense |
probably benign |
|
|
R6969:Ltn1
|
UTSW |
16 |
87,212,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Ltn1
|
UTSW |
16 |
87,220,361 (GRCm39) |
missense |
probably benign |
|
|
R7038:Ltn1
|
UTSW |
16 |
87,221,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7062:Ltn1
|
UTSW |
16 |
87,224,491 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7152:Ltn1
|
UTSW |
16 |
87,224,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ltn1
|
UTSW |
16 |
87,215,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7247:Ltn1
|
UTSW |
16 |
87,206,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7471:Ltn1
|
UTSW |
16 |
87,194,787 (GRCm39) |
missense |
probably benign |
|
|
R7511:Ltn1
|
UTSW |
16 |
87,205,716 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7691:Ltn1
|
UTSW |
16 |
87,195,574 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7702:Ltn1
|
UTSW |
16 |
87,223,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7761:Ltn1
|
UTSW |
16 |
87,208,681 (GRCm39) |
missense |
probably benign |
|
|
R8002:Ltn1
|
UTSW |
16 |
87,212,835 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8101:Ltn1
|
UTSW |
16 |
87,215,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8142:Ltn1
|
UTSW |
16 |
87,178,529 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8214:Ltn1
|
UTSW |
16 |
87,177,691 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8674:Ltn1
|
UTSW |
16 |
87,195,673 (GRCm39) |
missense |
probably benign |
|
|
R8783:Ltn1
|
UTSW |
16 |
87,207,247 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8839:Ltn1
|
UTSW |
16 |
87,215,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8885:Ltn1
|
UTSW |
16 |
87,178,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8889:Ltn1
|
UTSW |
16 |
87,229,230 (GRCm39) |
intron |
probably benign |
|
|
R8892:Ltn1
|
UTSW |
16 |
87,229,230 (GRCm39) |
intron |
probably benign |
|
|
R8919:Ltn1
|
UTSW |
16 |
87,178,381 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8970:Ltn1
|
UTSW |
16 |
87,212,926 (GRCm39) |
missense |
probably benign |
|
|
R9113:Ltn1
|
UTSW |
16 |
87,224,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Ltn1
|
UTSW |
16 |
87,197,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9208:Ltn1
|
UTSW |
16 |
87,197,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9234:Ltn1
|
UTSW |
16 |
87,194,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9421:Ltn1
|
UTSW |
16 |
87,215,375 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9558:Ltn1
|
UTSW |
16 |
87,220,295 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9654:Ltn1
|
UTSW |
16 |
87,207,227 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9738:Ltn1
|
UTSW |
16 |
87,222,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0028:Ltn1
|
UTSW |
16 |
87,199,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Ltn1
|
UTSW |
16 |
87,198,925 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGCCAAACCTTGTCCTC -3'
(R):5'- GCAATGCTGAAACCCATGTGTG -3'
Sequencing Primer
(F):5'- TAATGGGATCTGATGCCCAC -3'
(R):5'- GTGTGAAACACTAACATACATCTCC -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation