Incidental Mutation 'R0630:Gcn1'
| ID |
57824 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gcn1
|
| Ensembl Gene |
ENSMUSG00000041638 |
| Gene Name |
GCN1 activator of EIF2AK4 |
| Synonyms |
Gcn1l1, G431004K08Rik, GCN1L |
| MMRRC Submission |
038819-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.948)
|
| Stock # |
R0630 (G1)
|
| Quality Score |
145 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
115703313-115760713 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 115719148 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Threonine
at position 334
(A334T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000069432
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064454]
|
| AlphaFold |
E9PVA8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064454
AA Change: A334T
PolyPhen 2
Score 0.058 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000069432
Gene: ENSMUSG00000041638
AA Change: A334T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
64 |
84 |
N/A |
INTRINSIC |
|
low complexity region
|
108 |
117 |
N/A |
INTRINSIC |
|
low complexity region
|
142 |
154 |
N/A |
INTRINSIC |
|
Pfam:DUF3554
|
357 |
705 |
2e-61 |
PFAM |
|
coiled coil region
|
806 |
866 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1028 |
1068 |
6e-11 |
BLAST |
|
coiled coil region
|
1180 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1457 |
1466 |
N/A |
INTRINSIC |
|
low complexity region
|
1501 |
1510 |
N/A |
INTRINSIC |
|
ARM
|
1527 |
1567 |
3.69e1 |
SMART |
|
Blast:ARM
|
1602 |
1644 |
1e-5 |
BLAST |
|
Blast:EZ_HEAT
|
1671 |
1704 |
1e-7 |
BLAST |
|
low complexity region
|
1926 |
1934 |
N/A |
INTRINSIC |
|
low complexity region
|
1956 |
1972 |
N/A |
INTRINSIC |
|
ARM
|
2034 |
2070 |
9.27e1 |
SMART |
|
low complexity region
|
2326 |
2334 |
N/A |
INTRINSIC |
|
ARM
|
2416 |
2455 |
2.16e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125299
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129424
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000136041
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141472
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000184777
|
| Meta Mutation Damage Score |
0.0966 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 99.0%
- 10x: 97.9%
- 20x: 96.2%
|
| Validation Efficiency |
97% (108/111) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700056E22Rik |
C |
T |
1: 183,766,104 (GRCm39) |
|
probably benign |
Het |
| 4930562C15Rik |
T |
A |
16: 4,668,803 (GRCm39) |
N731K |
possibly damaging |
Het |
| Adgra1 |
A |
T |
7: 139,432,500 (GRCm39) |
K113* |
probably null |
Het |
| Adgrl2 |
T |
C |
3: 148,544,880 (GRCm39) |
I659M |
probably damaging |
Het |
| Adm |
G |
T |
7: 110,227,755 (GRCm39) |
R41L |
probably damaging |
Het |
| Aimp2 |
T |
C |
5: 143,843,419 (GRCm39) |
E97G |
probably benign |
Het |
| Aox1 |
T |
C |
1: 58,376,480 (GRCm39) |
|
probably benign |
Het |
| Arhgap20 |
G |
A |
9: 51,760,684 (GRCm39) |
R809H |
probably damaging |
Het |
| Arsa |
T |
C |
15: 89,358,207 (GRCm39) |
|
probably benign |
Het |
| Atg2a |
G |
T |
19: 6,294,547 (GRCm39) |
A88S |
probably damaging |
Het |
| Atm |
G |
A |
9: 53,442,922 (GRCm39) |
|
probably benign |
Het |
| Atp1a2 |
A |
T |
1: 172,118,842 (GRCm39) |
I100N |
possibly damaging |
Het |
| Camta2 |
G |
C |
11: 70,569,131 (GRCm39) |
L605V |
probably damaging |
Het |
| Cand2 |
G |
A |
6: 115,780,766 (GRCm39) |
E1217K |
probably damaging |
Het |
| Ccdc60 |
A |
G |
5: 116,274,440 (GRCm39) |
V388A |
possibly damaging |
Het |
| Cdk14 |
C |
T |
5: 5,185,422 (GRCm39) |
|
probably benign |
Het |
| Cdyl2 |
C |
T |
8: 117,350,774 (GRCm39) |
G119E |
probably benign |
Het |
| Celsr3 |
A |
G |
9: 108,704,891 (GRCm39) |
N458S |
probably damaging |
Het |
| Chd3 |
A |
C |
11: 69,238,021 (GRCm39) |
H1808Q |
probably damaging |
Het |
| Cntnap2 |
T |
C |
6: 46,965,694 (GRCm39) |
V835A |
probably damaging |
Het |
| Col4a1 |
C |
A |
8: 11,249,889 (GRCm39) |
|
probably benign |
Het |
| Cpsf1 |
A |
G |
15: 76,486,171 (GRCm39) |
V357A |
probably damaging |
Het |
| Cryzl1 |
A |
G |
16: 91,504,107 (GRCm39) |
|
probably benign |
Het |
| Cts8 |
T |
C |
13: 61,401,256 (GRCm39) |
K90R |
possibly damaging |
Het |
| Cux1 |
A |
G |
5: 136,315,689 (GRCm39) |
V1117A |
probably damaging |
Het |
| Dbx1 |
T |
C |
7: 49,282,444 (GRCm39) |
T254A |
probably damaging |
Het |
| Dgki |
C |
A |
6: 36,977,133 (GRCm39) |
C659F |
probably damaging |
Het |
| Dnajc1 |
T |
G |
2: 18,236,612 (GRCm39) |
D332A |
probably damaging |
Het |
| Dock8 |
C |
A |
19: 25,038,524 (GRCm39) |
T70K |
probably benign |
Het |
| Dsc1 |
T |
A |
18: 20,218,919 (GRCm39) |
T828S |
probably damaging |
Het |
| Dst |
T |
G |
1: 34,232,531 (GRCm39) |
V3510G |
probably benign |
Het |
| Dst |
T |
C |
1: 34,238,554 (GRCm39) |
V1738A |
probably damaging |
Het |
| Ehmt2 |
A |
G |
17: 35,118,818 (GRCm39) |
T167A |
probably benign |
Het |
| Eri2 |
A |
T |
7: 119,385,640 (GRCm39) |
V287E |
probably benign |
Het |
| Fat4 |
T |
A |
3: 39,054,321 (GRCm39) |
L4121H |
probably damaging |
Het |
| Fbn1 |
T |
A |
2: 125,236,690 (GRCm39) |
D330V |
possibly damaging |
Het |
| Fign |
A |
G |
2: 63,810,485 (GRCm39) |
Y262H |
possibly damaging |
Het |
| Fnd3c2 |
C |
T |
X: 105,282,763 (GRCm39) |
M593I |
probably benign |
Het |
| Fndc7 |
T |
A |
3: 108,783,931 (GRCm39) |
E226V |
probably damaging |
Het |
| Gad2 |
A |
T |
2: 22,580,348 (GRCm39) |
Q583L |
probably benign |
Het |
| Ggt1 |
A |
G |
10: 75,421,336 (GRCm39) |
|
probably null |
Het |
| Gli2 |
C |
T |
1: 118,769,648 (GRCm39) |
G635R |
possibly damaging |
Het |
| Gm10253 |
T |
C |
3: 88,646,420 (GRCm39) |
E93G |
unknown |
Het |
| Gm10428 |
A |
G |
11: 62,644,256 (GRCm39) |
|
probably benign |
Het |
| Gm7104 |
T |
C |
12: 88,252,479 (GRCm39) |
|
noncoding transcript |
Het |
| Gm8258 |
T |
G |
5: 104,924,385 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr107 |
A |
G |
2: 31,104,309 (GRCm39) |
N538S |
possibly damaging |
Het |
| Hars1 |
T |
C |
18: 36,904,442 (GRCm39) |
E190G |
probably damaging |
Het |
| Hoxc10 |
C |
T |
15: 102,875,917 (GRCm39) |
P209S |
probably benign |
Het |
| Ighg3 |
T |
C |
12: 113,323,714 (GRCm39) |
|
probably benign |
Het |
| Igsf10 |
C |
A |
3: 59,233,483 (GRCm39) |
W1750L |
probably damaging |
Het |
| Igsf5 |
C |
A |
16: 96,174,023 (GRCm39) |
|
probably benign |
Het |
| Itga10 |
T |
C |
3: 96,563,615 (GRCm39) |
|
probably benign |
Het |
| Ldhd |
T |
C |
8: 112,353,934 (GRCm39) |
K422R |
probably benign |
Het |
| Masp1 |
T |
C |
16: 23,271,169 (GRCm39) |
K693R |
probably benign |
Het |
| Mb21d2 |
G |
A |
16: 28,748,324 (GRCm39) |
A31V |
probably benign |
Het |
| Mbd1 |
T |
A |
18: 74,409,798 (GRCm39) |
|
probably benign |
Het |
| Mdm4 |
G |
A |
1: 132,919,491 (GRCm39) |
T459I |
possibly damaging |
Het |
| Megf10 |
A |
T |
18: 57,421,067 (GRCm39) |
I902F |
probably benign |
Het |
| Mta3 |
A |
G |
17: 84,022,056 (GRCm39) |
N37S |
probably damaging |
Het |
| Mterf3 |
T |
A |
13: 67,060,372 (GRCm39) |
Y372F |
probably damaging |
Het |
| Nbeal2 |
A |
G |
9: 110,465,102 (GRCm39) |
|
probably benign |
Het |
| Nbr1 |
T |
C |
11: 101,457,913 (GRCm39) |
|
probably benign |
Het |
| Ndst3 |
A |
G |
3: 123,355,720 (GRCm39) |
M103T |
probably damaging |
Het |
| Notch3 |
C |
A |
17: 32,366,446 (GRCm39) |
|
probably benign |
Het |
| Npr2 |
A |
T |
4: 43,641,219 (GRCm39) |
E415V |
probably benign |
Het |
| Or2n1c |
A |
G |
17: 38,519,304 (GRCm39) |
H56R |
probably damaging |
Het |
| Or4k40 |
T |
C |
2: 111,251,191 (GRCm39) |
Y35C |
probably damaging |
Het |
| Or52h9 |
G |
C |
7: 104,202,998 (GRCm39) |
V291L |
probably benign |
Het |
| Or5be3 |
A |
T |
2: 86,863,653 (GRCm39) |
M304K |
probably benign |
Het |
| Or8b50 |
T |
A |
9: 38,518,192 (GRCm39) |
F144I |
probably benign |
Het |
| Pappa2 |
T |
A |
1: 158,660,343 (GRCm39) |
D1246V |
probably benign |
Het |
| Pcdhgc5 |
A |
T |
18: 37,954,931 (GRCm39) |
D735V |
probably benign |
Het |
| Pik3ca |
A |
G |
3: 32,504,176 (GRCm39) |
Y622C |
possibly damaging |
Het |
| Plppr2 |
A |
G |
9: 21,859,197 (GRCm39) |
D438G |
probably benign |
Het |
| Ppfibp2 |
A |
T |
7: 107,337,806 (GRCm39) |
|
probably null |
Het |
| Prdm15 |
A |
T |
16: 97,638,907 (GRCm39) |
L77Q |
probably null |
Het |
| Prdm8 |
T |
C |
5: 98,332,380 (GRCm39) |
S94P |
probably damaging |
Het |
| Prkdc |
A |
T |
16: 15,628,665 (GRCm39) |
Q3470L |
probably damaging |
Het |
| Prl3c1 |
T |
C |
13: 27,384,674 (GRCm39) |
|
probably benign |
Het |
| Ptchd4 |
A |
T |
17: 42,688,076 (GRCm39) |
H206L |
probably benign |
Het |
| Rack1 |
G |
A |
11: 48,694,804 (GRCm39) |
|
probably benign |
Het |
| Rere |
T |
C |
4: 150,703,545 (GRCm39) |
L1509P |
probably damaging |
Het |
| Rgma |
T |
A |
7: 73,067,366 (GRCm39) |
L301Q |
probably damaging |
Het |
| Rgs6 |
T |
A |
12: 83,094,324 (GRCm39) |
|
probably benign |
Het |
| Rictor |
C |
A |
15: 6,823,973 (GRCm39) |
R1613S |
probably damaging |
Het |
| Ripk1 |
T |
G |
13: 34,211,764 (GRCm39) |
F358C |
probably damaging |
Het |
| Robo2 |
T |
C |
16: 73,713,093 (GRCm39) |
D1217G |
probably benign |
Het |
| Shc2 |
A |
T |
10: 79,461,975 (GRCm39) |
W357R |
probably null |
Het |
| Slc25a45 |
T |
C |
19: 5,930,556 (GRCm39) |
L81P |
probably damaging |
Het |
| Slc9c1 |
A |
T |
16: 45,363,483 (GRCm39) |
|
probably benign |
Het |
| Spats2 |
T |
C |
15: 99,083,909 (GRCm39) |
|
probably null |
Het |
| Stac3 |
A |
T |
10: 127,343,632 (GRCm39) |
E258V |
probably damaging |
Het |
| Thada |
A |
G |
17: 84,536,603 (GRCm39) |
S1648P |
probably damaging |
Het |
| Tmem168 |
T |
C |
6: 13,583,064 (GRCm39) |
T222A |
probably benign |
Het |
| Tmtc4 |
T |
C |
14: 123,163,502 (GRCm39) |
|
probably benign |
Het |
| Trappc14 |
A |
G |
5: 138,260,551 (GRCm39) |
S292P |
probably damaging |
Het |
| Trim38 |
T |
G |
13: 23,975,115 (GRCm39) |
Y351* |
probably null |
Het |
| Trip12 |
T |
C |
1: 84,771,636 (GRCm39) |
R213G |
possibly damaging |
Het |
| Vav3 |
C |
T |
3: 109,331,328 (GRCm39) |
R76W |
probably damaging |
Het |
| Vmn1r63 |
G |
T |
7: 5,806,263 (GRCm39) |
P123H |
probably damaging |
Het |
| Wdr5 |
A |
G |
2: 27,410,619 (GRCm39) |
N130S |
probably benign |
Het |
| Wnk4 |
C |
A |
11: 101,156,212 (GRCm39) |
R27S |
probably damaging |
Het |
| Ykt6 |
G |
A |
11: 5,909,323 (GRCm39) |
S44N |
probably benign |
Het |
| Ythdc1 |
T |
A |
5: 86,957,207 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Gcn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00869:Gcn1
|
APN |
5 |
115,726,202 (GRCm39) |
splice site |
probably benign |
|
|
IGL00974:Gcn1
|
APN |
5 |
115,751,852 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01566:Gcn1
|
APN |
5 |
115,749,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01843:Gcn1
|
APN |
5 |
115,757,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01885:Gcn1
|
APN |
5 |
115,714,174 (GRCm39) |
splice site |
probably null |
|
|
IGL02081:Gcn1
|
APN |
5 |
115,723,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02118:Gcn1
|
APN |
5 |
115,748,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02150:Gcn1
|
APN |
5 |
115,747,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02190:Gcn1
|
APN |
5 |
115,752,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02219:Gcn1
|
APN |
5 |
115,751,826 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02507:Gcn1
|
APN |
5 |
115,723,940 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02644:Gcn1
|
APN |
5 |
115,713,250 (GRCm39) |
missense |
probably benign |
|
|
IGL02678:Gcn1
|
APN |
5 |
115,751,814 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02748:Gcn1
|
APN |
5 |
115,748,859 (GRCm39) |
splice site |
probably null |
|
|
IGL02755:Gcn1
|
APN |
5 |
115,742,065 (GRCm39) |
splice site |
probably null |
|
|
IGL02896:Gcn1
|
APN |
5 |
115,757,707 (GRCm39) |
splice site |
probably benign |
|
|
cusp
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
farthing
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
IGL03147:Gcn1
|
UTSW |
5 |
115,748,917 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0362:Gcn1
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
R0540:Gcn1
|
UTSW |
5 |
115,727,015 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0569:Gcn1
|
UTSW |
5 |
115,733,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0570:Gcn1
|
UTSW |
5 |
115,730,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Gcn1
|
UTSW |
5 |
115,733,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0656:Gcn1
|
UTSW |
5 |
115,727,362 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0801:Gcn1
|
UTSW |
5 |
115,729,065 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0890:Gcn1
|
UTSW |
5 |
115,717,852 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1400:Gcn1
|
UTSW |
5 |
115,752,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1485:Gcn1
|
UTSW |
5 |
115,712,676 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1673:Gcn1
|
UTSW |
5 |
115,720,356 (GRCm39) |
missense |
probably benign |
|
|
R1894:Gcn1
|
UTSW |
5 |
115,727,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2114:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2116:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2117:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2152:Gcn1
|
UTSW |
5 |
115,747,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2162:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2216:Gcn1
|
UTSW |
5 |
115,731,720 (GRCm39) |
missense |
probably benign |
|
|
R2218:Gcn1
|
UTSW |
5 |
115,757,720 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2278:Gcn1
|
UTSW |
5 |
115,749,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2280:Gcn1
|
UTSW |
5 |
115,750,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Gcn1
|
UTSW |
5 |
115,717,876 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3729:Gcn1
|
UTSW |
5 |
115,721,453 (GRCm39) |
splice site |
probably benign |
|
|
R3833:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R3932:Gcn1
|
UTSW |
5 |
115,725,893 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4067:Gcn1
|
UTSW |
5 |
115,737,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Gcn1
|
UTSW |
5 |
115,751,413 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4179:Gcn1
|
UTSW |
5 |
115,726,109 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4292:Gcn1
|
UTSW |
5 |
115,714,207 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4350:Gcn1
|
UTSW |
5 |
115,741,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4493:Gcn1
|
UTSW |
5 |
115,732,203 (GRCm39) |
missense |
probably benign |
|
|
R4672:Gcn1
|
UTSW |
5 |
115,744,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Gcn1
|
UTSW |
5 |
115,752,461 (GRCm39) |
missense |
probably benign |
|
|
R4753:Gcn1
|
UTSW |
5 |
115,754,537 (GRCm39) |
missense |
probably benign |
|
|
R4826:Gcn1
|
UTSW |
5 |
115,731,752 (GRCm39) |
missense |
probably benign |
|
|
R4873:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4875:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4932:Gcn1
|
UTSW |
5 |
115,730,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4992:Gcn1
|
UTSW |
5 |
115,737,225 (GRCm39) |
missense |
probably benign |
0.29 |
|
R5049:Gcn1
|
UTSW |
5 |
115,744,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5211:Gcn1
|
UTSW |
5 |
115,757,371 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5226:Gcn1
|
UTSW |
5 |
115,726,126 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5338:Gcn1
|
UTSW |
5 |
115,721,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5914:Gcn1
|
UTSW |
5 |
115,748,194 (GRCm39) |
synonymous |
silent |
|
|
R5932:Gcn1
|
UTSW |
5 |
115,730,435 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6422:Gcn1
|
UTSW |
5 |
115,747,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6435:Gcn1
|
UTSW |
5 |
115,749,081 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6607:Gcn1
|
UTSW |
5 |
115,747,537 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6724:Gcn1
|
UTSW |
5 |
115,747,217 (GRCm39) |
splice site |
probably null |
|
|
R6861:Gcn1
|
UTSW |
5 |
115,749,108 (GRCm39) |
missense |
probably benign |
|
|
R6875:Gcn1
|
UTSW |
5 |
115,726,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Gcn1
|
UTSW |
5 |
115,744,597 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6975:Gcn1
|
UTSW |
5 |
115,751,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7027:Gcn1
|
UTSW |
5 |
115,754,605 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7038:Gcn1
|
UTSW |
5 |
115,749,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Gcn1
|
UTSW |
5 |
115,728,352 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7276:Gcn1
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7456:Gcn1
|
UTSW |
5 |
115,743,005 (GRCm39) |
nonsense |
probably null |
|
|
R7473:Gcn1
|
UTSW |
5 |
115,719,863 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7517:Gcn1
|
UTSW |
5 |
115,757,755 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7714:Gcn1
|
UTSW |
5 |
115,733,359 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7752:Gcn1
|
UTSW |
5 |
115,753,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7812:Gcn1
|
UTSW |
5 |
115,731,751 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7922:Gcn1
|
UTSW |
5 |
115,752,527 (GRCm39) |
missense |
probably benign |
|
|
R8070:Gcn1
|
UTSW |
5 |
115,727,057 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8218:Gcn1
|
UTSW |
5 |
115,719,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8329:Gcn1
|
UTSW |
5 |
115,747,921 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8413:Gcn1
|
UTSW |
5 |
115,717,698 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8795:Gcn1
|
UTSW |
5 |
115,752,454 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8802:Gcn1
|
UTSW |
5 |
115,747,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8899:Gcn1
|
UTSW |
5 |
115,717,220 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8946:Gcn1
|
UTSW |
5 |
115,733,404 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8963:Gcn1
|
UTSW |
5 |
115,727,153 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9006:Gcn1
|
UTSW |
5 |
115,719,566 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9163:Gcn1
|
UTSW |
5 |
115,742,944 (GRCm39) |
missense |
probably benign |
|
|
R9177:Gcn1
|
UTSW |
5 |
115,719,867 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9187:Gcn1
|
UTSW |
5 |
115,752,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Gcn1
|
UTSW |
5 |
115,733,098 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9541:Gcn1
|
UTSW |
5 |
115,754,416 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9574:Gcn1
|
UTSW |
5 |
115,713,341 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9630:Gcn1
|
UTSW |
5 |
115,741,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9651:Gcn1
|
UTSW |
5 |
115,747,665 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9761:Gcn1
|
UTSW |
5 |
115,729,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9765:Gcn1
|
UTSW |
5 |
115,735,131 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Gcn1
|
UTSW |
5 |
115,752,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1191:Gcn1
|
UTSW |
5 |
115,713,352 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGTAATCCTGGAAACCCCGTGATG -3'
(R):5'- TTCTTAAAGACACGGACACTGCCC -3'
Sequencing Primer
(F):5'- TTGATAGTTGAGGTCAGAGAGCC -3'
(R):5'- GACACTGCCCTCCGTTCG -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation