Mutagenetix > Incidental Mutation

Incidental Mutation 'R7468:Efcab3'

578977

Institutional Source

Beutler Lab

Gene Symbol

Efcab3

Ensembl Gene

ENSMUSG00000020690

Gene Name

EF-hand calcium binding domain 3

Synonyms

Gm11639, Efcab13, 4921510J17Rik, Efcab15, Gm11639

MMRRC Submission

045542-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7468 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

104954418-105008363 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 104640526 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Isoleucine at position 1088 (S1088I)

Ref Sequence

ENSEMBL: ENSMUSP00000148433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000148007] [ENSMUST00000212287]

AlphaFold

Q80X60

Predicted Effect

possibly damaging
Transcript: ENSMUST00000148007
AA Change: S1036I

PolyPhen 2 Score 0.905 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000116040
Gene: ENSMUSG00000040838
AA Change: S1036I

Domain	Start	End	E-Value	Type
low complexity region	40	55	N/A	INTRINSIC
low complexity region	116	129	N/A	INTRINSIC
internal_repeat_4	146	233	3.42e-6	PROSPERO
internal_repeat_3	165	247	2.21e-6	PROSPERO
low complexity region	331	348	N/A	INTRINSIC
internal_repeat_2	349	361	4.38e-8	PROSPERO
internal_repeat_2	371	383	4.38e-8	PROSPERO
low complexity region	385	640	N/A	INTRINSIC
Pfam:EF-hand_8	677	729	8.7e-6	PFAM
low complexity region	835	842	N/A	INTRINSIC
internal_repeat_1	879	1106	2.47e-14	PROSPERO
internal_repeat_4	1015	1108	3.42e-6	PROSPERO

Predicted Effect

probably benign
Transcript: ENSMUST00000212287
AA Change: S1088I

PolyPhen 2 Score 0.168 (Sensitivity: 0.92; Specificity: 0.87)

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

98% (86/88)

Allele List at MGI

Other mutations in this stock

Total: 88 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abl2	T	G	1: 156,450,104 (GRCm39)	N90K	possibly damaging	Het
Acox1	T	C	11: 116,069,001 (GRCm39)	T415A	possibly damaging	Het
Acy1	T	C	9: 106,314,921 (GRCm39)	M1V	probably null	Het
Akap13	G	A	7: 75,380,213 (GRCm39)	R462H	probably damaging	Het
Alpk3	C	A	7: 80,750,746 (GRCm39)	Y1505*	probably null	Het
Ankrd17	T	C	5: 90,390,902 (GRCm39)	N2256S	probably benign	Het
Ankrd22	C	A	19: 34,126,692 (GRCm39)	C46F	possibly damaging	Het
Arhgef5	A	T	6: 43,257,605 (GRCm39)	K1291*	probably null	Het
Arl9	T	A	5: 77,158,276 (GRCm39)	Y119*	probably null	Het
Asb14	T	C	14: 26,622,805 (GRCm39)	V89A	probably benign	Het
Banp	T	G	8: 122,676,588 (GRCm39)		probably null	Het
Btn2a2	T	C	13: 23,666,933 (GRCm39)	N224S	probably benign	Het
C1ra	C	T	6: 124,499,403 (GRCm39)	Q530*	probably null	Het
C2cd6	A	C	1: 59,107,844 (GRCm39)	S273A	probably benign	Het
Cd1d2	A	T	3: 86,895,583 (GRCm39)		probably null	Het
Cdc42bpb	T	C	12: 111,306,307 (GRCm39)	D132G	probably damaging	Het
Cfap45	C	A	1: 172,362,877 (GRCm39)	Y289*	probably null	Het
Chrdl2	T	C	7: 99,659,332 (GRCm39)		probably null	Het
Cilk1	A	G	9: 78,065,221 (GRCm39)	K377R	probably benign	Het
Cst5	C	T	2: 149,247,496 (GRCm39)	L71F	probably benign	Het
Dcaf11	T	C	14: 55,802,966 (GRCm39)	F292L	possibly damaging	Het
Dgcr8	A	G	16: 18,077,487 (GRCm39)	F641S	probably damaging	Het
Dnm3	G	A	1: 162,149,198 (GRCm39)		probably null	Het
Eral1	T	C	11: 77,966,219 (GRCm39)	K320E	probably damaging	Het
Eva1a	A	G	6: 82,069,002 (GRCm39)	T110A	possibly damaging	Het
Fbxo42	A	G	4: 140,926,917 (GRCm39)	D399G	possibly damaging	Het
Frs2	T	C	10: 116,910,007 (GRCm39)	T452A	possibly damaging	Het
Git2	T	A	5: 114,871,958 (GRCm39)	D542V	probably damaging	Het
Grk2	T	A	19: 4,356,063 (GRCm39)		probably benign	Het
Gsg1l2	A	G	11: 67,676,110 (GRCm39)	N158S	possibly damaging	Het
Hc	T	C	2: 34,918,063 (GRCm39)	N740S	probably benign	Het
Hectd1	T	C	12: 51,791,588 (GRCm39)		probably null	Het
Hemk1	A	G	9: 107,208,288 (GRCm39)		probably null	Het
Hormad2	G	T	11: 4,362,245 (GRCm39)	Y126*	probably null	Het
Hr	A	G	14: 70,795,652 (GRCm39)	E399G	possibly damaging	Het
Ilf3	C	A	9: 21,314,707 (GRCm39)	H780N	unknown	Het
Inpp5e	A	T	2: 26,298,161 (GRCm39)	S147T	probably benign	Het
Irag2	C	A	6: 145,119,427 (GRCm39)		probably null	Het
Jmjd6	T	C	11: 116,733,275 (GRCm39)	D134G	probably damaging	Het
Kif23	G	T	9: 61,844,457 (GRCm39)	Y120*	probably null	Het
Klk12	T	A	7: 43,422,780 (GRCm39)	Y236N	probably damaging	Het
Kmt5b	C	A	19: 3,852,799 (GRCm39)	Y186*	probably null	Het
Krtap9-5	A	G	11: 99,840,132 (GRCm39)	T278A	unknown	Het
Lca5	T	A	9: 83,305,509 (GRCm39)	D99V	probably damaging	Het
Leng9	A	G	7: 4,151,800 (GRCm39)	V292A	probably benign	Het
Lime1	A	G	2: 181,025,135 (GRCm39)	R231G	probably benign	Het
Mctp2	T	A	7: 71,861,438 (GRCm39)	E402D	probably damaging	Het
Mrpl28	T	A	17: 26,343,589 (GRCm39)	S116R	probably damaging	Het
Muc15	A	T	2: 110,561,862 (GRCm39)	R99S	probably benign	Het
Myh2	G	A	11: 67,083,368 (GRCm39)	A1444T	probably benign	Het
Mynn	T	A	3: 30,657,825 (GRCm39)	Y48N	probably damaging	Het
Myo1b	A	T	1: 51,836,639 (GRCm39)	V274E	possibly damaging	Het
Nemp1	T	A	10: 127,528,923 (GRCm39)	M209K	possibly damaging	Het
Nlrc4	G	T	17: 74,752,507 (GRCm39)	D625E	probably benign	Het
Or10al6	C	T	17: 38,082,910 (GRCm39)	A122V	probably damaging	Het
Or11a4	T	C	17: 37,536,276 (GRCm39)	F87L	probably benign	Het
Or4p4	T	C	2: 88,482,622 (GRCm39)	L42P	probably damaging	Het
Otog	T	C	7: 45,913,543 (GRCm39)	V792A	probably benign	Het
Paqr8	T	C	1: 21,005,442 (GRCm39)	Y199H	probably damaging	Het
Popdc3	A	G	10: 45,191,117 (GRCm39)	D76G	probably damaging	Het
Ppme1	T	C	7: 99,991,069 (GRCm39)	N210D	probably benign	Het
Prdm15	A	C	16: 97,636,842 (GRCm39)	Y158*	probably null	Het
Prrg2	A	T	7: 44,709,687 (GRCm39)	L70Q	probably benign	Het
Psmg4	C	T	13: 34,361,966 (GRCm39)	R85W	probably damaging	Het
Rab11fip4	A	T	11: 79,580,478 (GRCm39)	T437S	probably benign	Het
Rap2a	T	A	14: 120,716,338 (GRCm39)	M67K	probably damaging	Het
Rnf123	A	T	9: 107,946,208 (GRCm39)	H322Q	probably benign	Het
Rxfp2	A	T	5: 149,990,801 (GRCm39)	T521S	possibly damaging	Het
Scrn2	T	G	11: 96,923,992 (GRCm39)	V292G	possibly damaging	Het
Serpina3n	C	A	12: 104,377,656 (GRCm39)	P303H	probably benign	Het
Spop	C	T	11: 95,376,727 (GRCm39)	T260M	probably damaging	Het
Surf2	G	A	2: 26,809,354 (GRCm39)	G224D	probably benign	Het
Synm	T	G	7: 67,382,971 (GRCm39)	N669T	unknown	Het
Tmprss13	T	C	9: 45,239,721 (GRCm39)	S10P	unknown	Het
Trav9d-1	T	A	14: 53,029,970 (GRCm39)	S25T	probably benign	Het
Trpc3	A	T	3: 36,678,565 (GRCm39)	I840K	probably damaging	Het
Tsbp1	T	A	17: 34,636,539 (GRCm39)		probably null	Het
Tssc4	C	A	7: 142,622,999 (GRCm39)		probably benign	Het
Ttc39d	G	T	17: 80,523,579 (GRCm39)	R79S	possibly damaging	Het
Txlnb	T	A	10: 17,675,082 (GRCm39)	S78R	probably damaging	Het
Vmn1r142	T	A	7: 21,862,784 (GRCm39)	Q226L	possibly damaging	Het
Vmn1r230	T	C	17: 21,067,146 (GRCm39)	S112P	probably damaging	Het
Wrnip1	T	C	13: 33,000,360 (GRCm39)	F456L	possibly damaging	Het
Zc3h8	G	T	2: 128,775,215 (GRCm39)	H148Q	probably benign	Het
Zcchc3	A	G	2: 152,256,615 (GRCm39)	V28A	probably benign	Het
Zdbf2	T	A	1: 63,346,669 (GRCm39)	C1683S	probably benign	Het
Zfp874a	T	C	13: 67,573,723 (GRCm39)		probably null	Het
Zmym4	A	G	4: 126,776,029 (GRCm39)	S1260P	probably benign	Het

Other mutations in Efcab3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00897:Efcab3	APN	11	104,990,847 (GRCm39)	missense	probably damaging	1.00
IGL01308:Efcab3	APN	11	104,611,523 (GRCm39)	missense	probably benign	0.03
IGL01483:Efcab3	APN	11	104,630,173 (GRCm39)	missense	probably benign	0.03
IGL01695:Efcab3	APN	11	104,626,889 (GRCm39)	missense	probably damaging	1.00
IGL01860:Efcab3	APN	11	104,581,747 (GRCm39)	missense	probably benign	0.16
IGL01981:Efcab3	APN	11	104,612,258 (GRCm39)	intron	probably benign
IGL01984:Efcab3	APN	11	104,629,134 (GRCm39)	missense	probably benign	0.20
IGL02023:Efcab3	APN	11	104,612,258 (GRCm39)	intron	probably benign
IGL02252:Efcab3	APN	11	104,644,753 (GRCm39)	missense	possibly damaging	0.68
IGL02886:Efcab3	APN	11	104,986,700 (GRCm39)	missense	possibly damaging	0.95
IGL03116:Efcab3	APN	11	104,612,359 (GRCm39)	missense	probably benign	0.02
IGL03141:Efcab3	APN	11	104,986,696 (GRCm39)	missense	probably damaging	0.99
IGL03242:Efcab3	APN	11	104,997,230 (GRCm39)	missense	probably damaging	1.00
IGL03274:Efcab3	APN	11	104,611,919 (GRCm39)	missense	probably benign	0.03
IGL03408:Efcab3	APN	11	104,601,447 (GRCm39)	missense	probably benign	0.03
PIT4812001:Efcab3	UTSW	11	104,990,805 (GRCm39)	missense	probably null	0.00
R0018:Efcab3	UTSW	11	104,612,378 (GRCm39)	critical splice donor site	probably null
R0068:Efcab3	UTSW	11	104,611,648 (GRCm39)	missense	probably benign	0.29
R0350:Efcab3	UTSW	11	104,581,706 (GRCm39)	missense	probably benign	0.03
R0388:Efcab3	UTSW	11	105,000,227 (GRCm39)	missense	possibly damaging	0.61
R0646:Efcab3	UTSW	11	104,611,327 (GRCm39)	missense	probably benign	0.03
R0668:Efcab3	UTSW	11	104,611,318 (GRCm39)	missense	probably benign	0.16
R0715:Efcab3	UTSW	11	104,611,706 (GRCm39)	missense	possibly damaging	0.90
R0944:Efcab3	UTSW	11	104,601,556 (GRCm39)	splice site	probably null
R1330:Efcab3	UTSW	11	104,637,116 (GRCm39)	missense	possibly damaging	0.84
R1440:Efcab3	UTSW	11	104,999,581 (GRCm39)	splice site	probably benign
R1508:Efcab3	UTSW	11	104,601,503 (GRCm39)	missense	probably benign	0.03
R1540:Efcab3	UTSW	11	104,999,726 (GRCm39)	missense	probably benign	0.07
R1643:Efcab3	UTSW	11	104,589,804 (GRCm39)	missense	probably benign	0.16
R1651:Efcab3	UTSW	11	104,611,492 (GRCm39)	missense	probably benign	0.03
R1665:Efcab3	UTSW	11	104,611,940 (GRCm39)	missense	probably benign	0.07
R1702:Efcab3	UTSW	11	104,581,832 (GRCm39)	missense	probably benign	0.03
R1711:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1779:Efcab3	UTSW	11	104,611,765 (GRCm39)	missense	probably benign	0.15
R1813:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1818:Efcab3	UTSW	11	104,612,333 (GRCm39)	missense	probably benign	0.10
R1896:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1969:Efcab3	UTSW	11	104,637,090 (GRCm39)	missense	probably damaging	1.00
R2029:Efcab3	UTSW	11	104,990,851 (GRCm39)	missense	probably damaging	0.99
R2139:Efcab3	UTSW	11	104,642,737 (GRCm39)	missense	possibly damaging	0.53
R2165:Efcab3	UTSW	11	104,642,688 (GRCm39)	missense	possibly damaging	0.93
R2359:Efcab3	UTSW	11	104,630,106 (GRCm39)	missense	possibly damaging	0.80
R2394:Efcab3	UTSW	11	104,629,121 (GRCm39)	missense	probably benign	0.17
R2401:Efcab3	UTSW	11	104,963,144 (GRCm39)	critical splice donor site	probably null
R2406:Efcab3	UTSW	11	104,611,457 (GRCm39)	missense	probably benign	0.03
R2570:Efcab3	UTSW	11	104,624,490 (GRCm39)	missense	probably damaging	1.00
R3795:Efcab3	UTSW	11	104,624,501 (GRCm39)	missense	possibly damaging	0.94
R3901:Efcab3	UTSW	11	104,974,713 (GRCm39)	missense	possibly damaging	0.68
R4244:Efcab3	UTSW	11	105,002,629 (GRCm39)	missense	probably damaging	1.00
R4352:Efcab3	UTSW	11	104,630,140 (GRCm39)	missense	probably null	0.25
R4359:Efcab3	UTSW	11	104,624,547 (GRCm39)	splice site	probably null
R4424:Efcab3	UTSW	11	104,626,940 (GRCm39)	critical splice donor site	probably null
R4895:Efcab3	UTSW	11	105,008,227 (GRCm39)	unclassified	probably benign
R4895:Efcab3	UTSW	11	104,640,496 (GRCm39)	missense	probably damaging	1.00
R4895:Efcab3	UTSW	11	104,611,112 (GRCm39)	missense	probably benign	0.16
R5006:Efcab3	UTSW	11	104,620,503 (GRCm39)	splice site	probably null
R5066:Efcab3	UTSW	11	104,611,490 (GRCm39)	missense	probably benign	0.03
R5316:Efcab3	UTSW	11	104,967,286 (GRCm39)	missense	possibly damaging	0.80
R5329:Efcab3	UTSW	11	104,644,632 (GRCm39)	splice site	probably null
R5405:Efcab3	UTSW	11	104,612,018 (GRCm39)	missense	probably benign	0.07
R5814:Efcab3	UTSW	11	104,626,940 (GRCm39)	critical splice donor site	probably benign
R5888:Efcab3	UTSW	11	104,612,227 (GRCm39)	splice site	probably benign
R5910:Efcab3	UTSW	11	104,581,760 (GRCm39)	missense	probably benign	0.01
R5975:Efcab3	UTSW	11	104,578,375 (GRCm39)	start gained	probably benign
R6019:Efcab3	UTSW	11	104,933,728 (GRCm39)	critical splice donor site	probably null
R6028:Efcab3	UTSW	11	104,660,481 (GRCm39)	critical splice donor site	probably null
R6048:Efcab3	UTSW	11	104,835,259 (GRCm39)	missense	unknown
R6059:Efcab3	UTSW	11	104,927,595 (GRCm39)	missense	probably benign	0.03
R6147:Efcab3	UTSW	11	104,858,566 (GRCm39)	missense	unknown
R6176:Efcab3	UTSW	11	104,683,383 (GRCm39)	missense	probably benign	0.16
R6181:Efcab3	UTSW	11	104,722,159 (GRCm39)	missense	probably benign	0.25
R6196:Efcab3	UTSW	11	104,746,386 (GRCm39)	missense	probably benign	0.07
R6245:Efcab3	UTSW	11	104,675,834 (GRCm39)	missense	probably benign	0.03
R6262:Efcab3	UTSW	11	104,784,579 (GRCm39)	missense	probably benign	0.24
R6263:Efcab3	UTSW	11	104,810,312 (GRCm39)	missense	unknown
R6277:Efcab3	UTSW	11	104,901,148 (GRCm39)	missense	possibly damaging	0.49
R6338:Efcab3	UTSW	11	104,734,034 (GRCm39)	nonsense	probably null
R6355:Efcab3	UTSW	11	104,896,511 (GRCm39)	missense	probably benign	0.29
R6356:Efcab3	UTSW	11	104,784,533 (GRCm39)	missense	probably benign	0.19
R6365:Efcab3	UTSW	11	104,815,412 (GRCm39)	missense	unknown
R6378:Efcab3	UTSW	11	104,999,620 (GRCm39)	missense	possibly damaging	0.83
R6391:Efcab3	UTSW	11	104,885,143 (GRCm39)	missense	possibly damaging	0.92
R6494:Efcab3	UTSW	11	104,990,845 (GRCm39)	missense	possibly damaging	0.93
R6556:Efcab3	UTSW	11	104,899,077 (GRCm39)	missense	probably null	0.03
R6573:Efcab3	UTSW	11	104,971,461 (GRCm39)	missense	possibly damaging	0.91
R6604:Efcab3	UTSW	11	104,589,772 (GRCm39)	nonsense	probably null
R6605:Efcab3	UTSW	11	104,890,107 (GRCm39)	splice site	probably null
R6634:Efcab3	UTSW	11	104,784,609 (GRCm39)	missense	probably benign	0.17
R6723:Efcab3	UTSW	11	105,007,906 (GRCm39)	missense	possibly damaging	0.95
R6851:Efcab3	UTSW	11	104,896,521 (GRCm39)	missense	probably benign	0.03
R6862:Efcab3	UTSW	11	104,612,284 (GRCm39)	nonsense	probably null
R6949:Efcab3	UTSW	11	104,799,896 (GRCm39)	missense	probably damaging	1.00
R6970:Efcab3	UTSW	11	104,667,182 (GRCm39)	missense	probably benign	0.03
R7014:Efcab3	UTSW	11	104,584,248 (GRCm39)	missense	probably benign	0.03
R7097:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R7122:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R7124:Efcab3	UTSW	11	104,629,100 (GRCm39)	missense	probably benign	0.17
R7146:Efcab3	UTSW	11	104,913,764 (GRCm39)	missense	probably benign	0.03
R7146:Efcab3	UTSW	11	104,858,578 (GRCm39)	missense	unknown
R7154:Efcab3	UTSW	11	104,589,966 (GRCm39)	splice site	probably null
R7175:Efcab3	UTSW	11	104,838,237 (GRCm39)	missense	unknown
R7189:Efcab3	UTSW	11	104,986,690 (GRCm39)	missense	probably benign
R7198:Efcab3	UTSW	11	104,642,711 (GRCm39)	missense	probably benign	0.15
R7211:Efcab3	UTSW	11	104,601,539 (GRCm39)	missense	probably benign	0.01
R7211:Efcab3	UTSW	11	104,615,435 (GRCm39)	critical splice donor site	probably null
R7216:Efcab3	UTSW	11	104,771,375 (GRCm39)	missense	possibly damaging	0.49
R7221:Efcab3	UTSW	11	104,791,432 (GRCm39)	missense	probably benign	0.36
R7233:Efcab3	UTSW	11	104,730,669 (GRCm39)	missense	possibly damaging	0.69
R7236:Efcab3	UTSW	11	104,790,093 (GRCm39)	missense	probably benign	0.10
R7262:Efcab3	UTSW	11	104,745,432 (GRCm39)	critical splice donor site	probably null
R7289:Efcab3	UTSW	11	104,929,184 (GRCm39)	missense	probably benign	0.24
R7323:Efcab3	UTSW	11	104,920,837 (GRCm39)	missense	probably benign	0.07
R7378:Efcab3	UTSW	11	104,605,528 (GRCm39)	missense	probably benign	0.03
R7388:Efcab3	UTSW	11	104,611,871 (GRCm39)	missense	probably damaging	0.97
R7390:Efcab3	UTSW	11	104,615,411 (GRCm39)	missense	possibly damaging	0.46
R7411:Efcab3	UTSW	11	104,890,549 (GRCm39)	missense	probably benign	0.10
R7483:Efcab3	UTSW	11	105,000,112 (GRCm39)	missense	probably benign	0.39
R7497:Efcab3	UTSW	11	104,653,516 (GRCm39)	critical splice donor site	probably null
R7612:Efcab3	UTSW	11	104,999,647 (GRCm39)	missense	possibly damaging	0.80
R7620:Efcab3	UTSW	11	104,722,969 (GRCm39)	missense	possibly damaging	0.95
R7638:Efcab3	UTSW	11	104,927,625 (GRCm39)	missense	probably benign	0.03
R7661:Efcab3	UTSW	11	104,617,503 (GRCm39)	missense	probably benign	0.03
R7667:Efcab3	UTSW	11	104,642,737 (GRCm39)	missense	possibly damaging	0.53
R7682:Efcab3	UTSW	11	104,855,174 (GRCm39)	splice site	probably null
R7708:Efcab3	UTSW	11	104,855,397 (GRCm39)	missense	unknown
R7719:Efcab3	UTSW	11	105,002,674 (GRCm39)	missense	probably benign	0.14
R7721:Efcab3	UTSW	11	104,615,366 (GRCm39)	nonsense	probably null
R7735:Efcab3	UTSW	11	104,962,465 (GRCm39)	missense	probably benign
R7747:Efcab3	UTSW	11	104,733,429 (GRCm39)	missense	probably damaging	0.96
R7840:Efcab3	UTSW	11	104,624,539 (GRCm39)	missense	probably benign	0.07
R7846:Efcab3	UTSW	11	104,605,571 (GRCm39)	critical splice donor site	probably null
R7893:Efcab3	UTSW	11	104,870,186 (GRCm39)	missense	unknown
R7895:Efcab3	UTSW	11	105,008,150 (GRCm39)	missense	probably benign	0.29
R7897:Efcab3	UTSW	11	104,889,061 (GRCm39)	missense	probably benign	0.24
R7936:Efcab3	UTSW	11	104,890,524 (GRCm39)	missense	possibly damaging	0.89
R7936:Efcab3	UTSW	11	104,937,385 (GRCm39)	critical splice donor site	probably null
R7959:Efcab3	UTSW	11	104,933,627 (GRCm39)	missense	probably damaging	0.96
R8031:Efcab3	UTSW	11	104,772,295 (GRCm39)	missense	possibly damaging	0.49
R8041:Efcab3	UTSW	11	104,810,305 (GRCm39)	missense	unknown
R8054:Efcab3	UTSW	11	104,621,226 (GRCm39)	missense	probably benign	0.07
R8056:Efcab3	UTSW	11	104,799,896 (GRCm39)	missense	probably damaging	0.98
R8061:Efcab3	UTSW	11	104,997,275 (GRCm39)	missense	probably benign	0.00
R8088:Efcab3	UTSW	11	104,889,072 (GRCm39)	missense	probably benign	0.10
R8112:Efcab3	UTSW	11	104,841,026 (GRCm39)	missense	unknown
R8116:Efcab3	UTSW	11	105,002,677 (GRCm39)	missense	possibly damaging	0.65
R8340:Efcab3	UTSW	11	104,876,856 (GRCm39)	missense	unknown
R8405:Efcab3	UTSW	11	104,612,024 (GRCm39)	missense	probably benign	0.02
R8413:Efcab3	UTSW	11	104,811,135 (GRCm39)	missense	unknown
R8472:Efcab3	UTSW	11	104,709,463 (GRCm39)	missense	probably benign	0.07
R8549:Efcab3	UTSW	11	104,890,521 (GRCm39)	missense	probably damaging	0.99
R8699:Efcab3	UTSW	11	104,672,072 (GRCm39)	missense	probably benign	0.03
R8711:Efcab3	UTSW	11	104,743,371 (GRCm39)	missense	probably benign	0.03
R8732:Efcab3	UTSW	11	104,695,100 (GRCm39)	missense	probably benign	0.03
R8745:Efcab3	UTSW	11	104,749,304 (GRCm39)	missense	possibly damaging	0.57
R8806:Efcab3	UTSW	11	104,928,695 (GRCm39)	missense	probably benign	0.07
R8810:Efcab3	UTSW	11	104,805,721 (GRCm39)	missense	unknown
R8845:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R8870:Efcab3	UTSW	11	104,791,500 (GRCm39)	missense	probably benign	0.07
R8872:Efcab3	UTSW	11	104,760,880 (GRCm39)	missense	probably benign	0.19
R8879:Efcab3	UTSW	11	104,581,781 (GRCm39)	missense	probably benign	0.03
R8924:Efcab3	UTSW	11	104,806,253 (GRCm39)	frame shift	probably null
R8954:Efcab3	UTSW	11	104,909,525 (GRCm39)	critical splice donor site	probably null
R8960:Efcab3	UTSW	11	104,820,772 (GRCm39)	splice site	probably benign
R8975:Efcab3	UTSW	11	104,954,415 (GRCm39)	missense	probably benign	0.17
R8988:Efcab3	UTSW	11	104,911,352 (GRCm39)	missense	probably benign	0.07
R8998:Efcab3	UTSW	11	104,640,477 (GRCm39)	missense	probably benign	0.09
R8999:Efcab3	UTSW	11	104,640,477 (GRCm39)	missense	probably benign	0.09
R9002:Efcab3	UTSW	11	104,920,822 (GRCm39)	missense	probably damaging	0.99
R9012:Efcab3	UTSW	11	104,711,347 (GRCm39)	critical splice donor site	probably null
R9036:Efcab3	UTSW	11	104,927,601 (GRCm39)	missense	probably benign	0.03
R9037:Efcab3	UTSW	11	104,803,791 (GRCm39)	missense	unknown
R9059:Efcab3	UTSW	11	104,642,689 (GRCm39)	missense	possibly damaging	0.73
R9066:Efcab3	UTSW	11	104,631,688 (GRCm39)	intron	probably benign
R9122:Efcab3	UTSW	11	104,856,605 (GRCm39)	missense	unknown
R9125:Efcab3	UTSW	11	104,736,360 (GRCm39)	missense	probably damaging	1.00
R9127:Efcab3	UTSW	11	104,741,407 (GRCm39)	missense	probably benign	0.07
R9171:Efcab3	UTSW	11	104,800,708 (GRCm39)	missense	probably benign	0.36
R9219:Efcab3	UTSW	11	104,836,691 (GRCm39)	missense	unknown
R9224:Efcab3	UTSW	11	104,661,801 (GRCm39)	missense	probably benign	0.07
R9235:Efcab3	UTSW	11	104,907,987 (GRCm39)	missense	probably benign	0.19
R9294:Efcab3	UTSW	11	104,722,126 (GRCm39)	missense	probably benign	0.24
R9318:Efcab3	UTSW	11	104,856,648 (GRCm39)	critical splice donor site	probably null
R9322:Efcab3	UTSW	11	104,765,199 (GRCm39)	missense	probably benign	0.36
R9361:Efcab3	UTSW	11	104,896,524 (GRCm39)	missense	probably benign	0.03
R9408:Efcab3	UTSW	11	104,621,255 (GRCm39)	critical splice donor site	probably null
R9434:Efcab3	UTSW	11	104,899,863 (GRCm39)	missense	probably benign	0.24
R9477:Efcab3	UTSW	11	104,836,698 (GRCm39)	missense	unknown
R9658:Efcab3	UTSW	11	104,611,120 (GRCm39)	missense	probably benign	0.03
R9719:Efcab3	UTSW	11	104,867,912 (GRCm39)	missense	unknown
R9751:Efcab3	UTSW	11	104,783,911 (GRCm39)	missense	probably benign	0.19
R9763:Efcab3	UTSW	11	104,890,485 (GRCm39)	missense	possibly damaging	0.89
X0026:Efcab3	UTSW	11	105,007,937 (GRCm39)	missense	probably benign	0.03
X0026:Efcab3	UTSW	11	104,611,801 (GRCm39)	missense	probably benign	0.07
Z1088:Efcab3	UTSW	11	104,642,728 (GRCm39)	missense	probably damaging	0.96
Z1176:Efcab3	UTSW	11	104,990,872 (GRCm39)	missense	probably damaging	1.00
Z1176:Efcab3	UTSW	11	104,892,793 (GRCm39)	missense	probably benign	0.29
Z1176:Efcab3	UTSW	11	104,999,598 (GRCm39)	nonsense	probably null
Z1177:Efcab3	UTSW	11	104,711,344 (GRCm39)	missense	probably benign	0.03
Z1177:Efcab3	UTSW	11	104,630,164 (GRCm39)	nonsense	probably null
Z1177:Efcab3	UTSW	11	104,814,845 (GRCm39)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- CACACAAACATGTAATTTAGTGATGC -3'
(R):5'- GGACAAGGTATGTGGTTATAAATTACT -3'

Sequencing Primer
(F):5'- TGATGCACACACATGTAATTTAGTG -3'
(R):5'- AGTTCCCATCACACATGTTGAGGG -3'

Posted On

2019-10-07