Incidental Mutation 'R7470:Ralgapa2'
| ID |
579091 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapa2
|
| Ensembl Gene |
ENSMUSG00000037110 |
| Gene Name |
Ral GTPase activating protein, alpha subunit 2 (catalytic) |
| Synonyms |
AS250, A230067G21Rik, RGC2 |
| MMRRC Submission |
045544-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.209)
|
| Stock # |
R7470 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
146081799-146354264 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 146266587 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 663
(L663P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105613
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000109986]
[ENSMUST00000131824]
[ENSMUST00000228797]
|
| AlphaFold |
A3KGS3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000109986
AA Change: L663P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000105613
Gene: ENSMUSG00000037110
AA Change: L663P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1296 |
1301 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1701 |
1877 |
6.8e-48 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000131824
AA Change: L663P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000122039
Gene: ENSMUSG00000037110
AA Change: L663P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
990 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1263 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1663 |
1842 |
1.3e-66 |
PFAM |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000122017
Gene: ENSMUSG00000037110
AA Change: L333P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
140 |
151 |
N/A |
INTRINSIC |
|
low complexity region
|
650 |
661 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
934 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1334 |
1511 |
2.4e-48 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000228797
AA Change: L663P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased incidence and severity of induced urothelial bladder tumors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930563M21Rik |
A |
T |
9: 55,898,622 (GRCm39) |
V238E |
possibly damaging |
Het |
| Actn3 |
G |
A |
19: 4,917,842 (GRCm39) |
S375L |
possibly damaging |
Het |
| Adgrg6 |
T |
C |
10: 14,319,810 (GRCm39) |
T476A |
probably benign |
Het |
| Afm |
T |
A |
5: 90,679,486 (GRCm39) |
S327T |
probably damaging |
Het |
| Apol7e |
T |
A |
15: 77,602,143 (GRCm39) |
M247K |
probably benign |
Het |
| Aqp12 |
T |
A |
1: 92,936,385 (GRCm39) |
L237Q |
probably damaging |
Het |
| Arhgef12 |
A |
T |
9: 42,951,848 (GRCm39) |
S63T |
probably damaging |
Het |
| Axdnd1 |
T |
A |
1: 156,204,086 (GRCm39) |
E393V |
|
Het |
| Cacna1g |
T |
A |
11: 94,352,765 (GRCm39) |
D365V |
possibly damaging |
Het |
| Ccdc3 |
T |
A |
2: 5,143,115 (GRCm39) |
V124E |
possibly damaging |
Het |
| Ccr7 |
C |
T |
11: 99,036,383 (GRCm39) |
V180M |
possibly damaging |
Het |
| Cd47 |
T |
A |
16: 49,704,585 (GRCm39) |
I119K |
|
Het |
| Cenpe |
A |
T |
3: 134,947,916 (GRCm39) |
L1158F |
probably damaging |
Het |
| Cfi |
A |
G |
3: 129,648,736 (GRCm39) |
R207G |
probably benign |
Het |
| Cyp2j6 |
T |
C |
4: 96,423,708 (GRCm39) |
Y220C |
probably benign |
Het |
| Ddhd2 |
A |
G |
8: 26,225,087 (GRCm39) |
F577L |
probably benign |
Het |
| Dhx40 |
T |
C |
11: 86,667,528 (GRCm39) |
E537G |
probably damaging |
Het |
| Disp3 |
A |
T |
4: 148,345,527 (GRCm39) |
C438S |
possibly damaging |
Het |
| Dock3 |
A |
G |
9: 106,882,644 (GRCm39) |
S380P |
probably damaging |
Het |
| Ehmt2 |
A |
G |
17: 35,118,372 (GRCm39) |
E106G |
possibly damaging |
Het |
| Fmnl2 |
A |
T |
2: 52,932,377 (GRCm39) |
I119F |
probably damaging |
Het |
| Gm11554 |
A |
C |
11: 99,695,190 (GRCm39) |
S8A |
unknown |
Het |
| Grm7 |
A |
G |
6: 111,478,476 (GRCm39) |
I54V |
|
Het |
| Hbs1l |
T |
C |
10: 21,234,683 (GRCm39) |
F579L |
possibly damaging |
Het |
| Hgf |
C |
A |
5: 16,823,854 (GRCm39) |
Q684K |
probably benign |
Het |
| Igsf3 |
T |
C |
3: 101,358,391 (GRCm39) |
Y741H |
possibly damaging |
Het |
| Il17rb |
C |
A |
14: 29,719,990 (GRCm39) |
G304W |
probably damaging |
Het |
| Ino80c |
C |
T |
18: 24,241,895 (GRCm39) |
W163* |
probably null |
Het |
| Kcnt1 |
A |
C |
2: 25,799,845 (GRCm39) |
D997A |
probably damaging |
Het |
| Klf7 |
C |
T |
1: 64,081,472 (GRCm39) |
|
probably null |
Het |
| Lingo1 |
T |
C |
9: 56,527,908 (GRCm39) |
Y233C |
probably damaging |
Het |
| Lmo7 |
C |
A |
14: 102,138,040 (GRCm39) |
T914K |
possibly damaging |
Het |
| Mark1 |
G |
T |
1: 184,660,241 (GRCm39) |
Y138* |
probably null |
Het |
| Mcm3ap |
C |
A |
10: 76,344,231 (GRCm39) |
T1791K |
probably damaging |
Het |
| Mcts2 |
T |
C |
2: 152,529,582 (GRCm39) |
I131T |
probably benign |
Het |
| Mipep |
A |
G |
14: 61,040,344 (GRCm39) |
D288G |
probably benign |
Het |
| Ms4a8a |
T |
A |
19: 11,053,714 (GRCm39) |
N131Y |
possibly damaging |
Het |
| Nalcn |
T |
C |
14: 123,809,456 (GRCm39) |
E232G |
probably benign |
Het |
| Nat10 |
C |
T |
2: 103,565,226 (GRCm39) |
A452T |
probably benign |
Het |
| Nfatc2 |
G |
A |
2: 168,365,227 (GRCm39) |
Q596* |
probably null |
Het |
| Nudt13 |
G |
T |
14: 20,359,791 (GRCm39) |
G173W |
probably damaging |
Het |
| Or10n1 |
C |
A |
9: 39,524,998 (GRCm39) |
T45K |
probably benign |
Het |
| Or1e16 |
T |
A |
11: 73,286,714 (GRCm39) |
I45F |
probably damaging |
Het |
| Or5l14 |
A |
T |
2: 87,792,793 (GRCm39) |
C148S |
possibly damaging |
Het |
| Or8b4 |
T |
A |
9: 37,830,592 (GRCm39) |
I213N |
probably damaging |
Het |
| Otud4 |
T |
C |
8: 80,399,989 (GRCm39) |
V901A |
probably benign |
Het |
| Pah |
G |
A |
10: 87,399,286 (GRCm39) |
R155Q |
probably damaging |
Het |
| Pkd1l3 |
A |
G |
8: 110,365,008 (GRCm39) |
H1130R |
probably benign |
Het |
| Pnliprp1 |
A |
G |
19: 58,720,457 (GRCm39) |
N111S |
possibly damaging |
Het |
| Ppp1r21 |
T |
C |
17: 88,869,649 (GRCm39) |
Y401H |
probably damaging |
Het |
| Prr14 |
A |
G |
7: 127,074,997 (GRCm39) |
K466R |
probably null |
Het |
| Reg3d |
A |
T |
6: 78,353,071 (GRCm39) |
C171S |
possibly damaging |
Het |
| Reln |
G |
T |
5: 22,147,739 (GRCm39) |
L2404I |
probably damaging |
Het |
| Rnasel |
A |
C |
1: 153,629,777 (GRCm39) |
I98L |
probably benign |
Het |
| Rnf216 |
T |
C |
5: 142,978,480 (GRCm39) |
D886G |
possibly damaging |
Het |
| Rp1l1 |
A |
G |
14: 64,266,015 (GRCm39) |
R534G |
probably benign |
Het |
| Selenon |
A |
C |
4: 134,267,061 (GRCm39) |
S514A |
probably benign |
Het |
| Sema3d |
T |
A |
5: 12,558,152 (GRCm39) |
I228N |
probably damaging |
Het |
| Serpinb9g |
T |
A |
13: 33,670,617 (GRCm39) |
I35N |
probably damaging |
Het |
| Siglec1 |
A |
C |
2: 130,917,744 (GRCm39) |
H1044Q |
probably benign |
Het |
| Skint5 |
T |
A |
4: 113,614,128 (GRCm39) |
I693F |
unknown |
Het |
| Skint5 |
G |
T |
4: 113,743,000 (GRCm39) |
L370M |
unknown |
Het |
| Slc12a1 |
G |
A |
2: 125,059,815 (GRCm39) |
W905* |
probably null |
Het |
| Slc26a9 |
G |
C |
1: 131,691,781 (GRCm39) |
V675L |
probably benign |
Het |
| Slc5a7 |
A |
T |
17: 54,583,990 (GRCm39) |
Y433* |
probably null |
Het |
| Slc7a4 |
A |
G |
16: 17,392,977 (GRCm39) |
I274T |
probably benign |
Het |
| Slmap |
A |
G |
14: 26,148,575 (GRCm39) |
V612A |
probably benign |
Het |
| Spen |
T |
C |
4: 141,206,605 (GRCm39) |
D674G |
unknown |
Het |
| Ssh1 |
T |
C |
5: 114,080,488 (GRCm39) |
T981A |
possibly damaging |
Het |
| Sycp2l |
T |
C |
13: 41,316,580 (GRCm39) |
S180P |
probably benign |
Het |
| Tdrd7 |
C |
A |
4: 45,990,144 (GRCm39) |
S181R |
probably benign |
Het |
| Thada |
T |
C |
17: 84,533,469 (GRCm39) |
N1661D |
probably benign |
Het |
| Tsga13 |
C |
A |
6: 30,876,981 (GRCm39) |
D179Y |
possibly damaging |
Het |
| Ttf2 |
T |
G |
3: 100,870,478 (GRCm39) |
Q198H |
possibly damaging |
Het |
| Ugt2b37 |
T |
G |
5: 87,401,971 (GRCm39) |
Y220S |
probably benign |
Het |
| Unc79 |
C |
T |
12: 103,061,235 (GRCm39) |
T1145I |
probably damaging |
Het |
| Unc80 |
T |
A |
1: 66,661,621 (GRCm39) |
M1682K |
probably benign |
Het |
| Vcp |
A |
G |
4: 42,982,891 (GRCm39) |
S652P |
probably damaging |
Het |
| Vmn2r-ps158 |
T |
A |
7: 42,697,310 (GRCm39) |
M789K |
probably damaging |
Het |
| Wrnip1 |
T |
A |
13: 33,000,310 (GRCm39) |
L439* |
probably null |
Het |
| Zfhx2 |
A |
G |
14: 55,304,207 (GRCm39) |
I1259T |
possibly damaging |
Het |
| Zfp369 |
A |
T |
13: 65,439,960 (GRCm39) |
T215S |
probably benign |
Het |
| Zfp64 |
A |
T |
2: 168,767,731 (GRCm39) |
V627E |
probably damaging |
Het |
| Zfp873 |
T |
C |
10: 81,895,773 (GRCm39) |
I168T |
probably benign |
Het |
|
| Other mutations in Ralgapa2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00666:Ralgapa2
|
APN |
2 |
146,327,056 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL00915:Ralgapa2
|
APN |
2 |
146,184,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01012:Ralgapa2
|
APN |
2 |
146,263,659 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,113 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01902:Ralgapa2
|
APN |
2 |
146,156,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ralgapa2
|
APN |
2 |
146,190,360 (GRCm39) |
splice site |
probably benign |
|
|
IGL02321:Ralgapa2
|
APN |
2 |
146,254,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02412:Ralgapa2
|
APN |
2 |
146,254,052 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03026:Ralgapa2
|
APN |
2 |
146,302,695 (GRCm39) |
splice site |
probably benign |
|
|
IGL03115:Ralgapa2
|
APN |
2 |
146,266,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03256:Ralgapa2
|
APN |
2 |
146,302,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03379:Ralgapa2
|
APN |
2 |
146,199,907 (GRCm39) |
missense |
probably benign |
0.01 |
|
Chow
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
purina
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P4748:Ralgapa2
|
UTSW |
2 |
146,188,731 (GRCm39) |
nonsense |
probably null |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0165:Ralgapa2
|
UTSW |
2 |
146,230,407 (GRCm39) |
splice site |
probably benign |
|
|
R0344:Ralgapa2
|
UTSW |
2 |
146,188,714 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0402:Ralgapa2
|
UTSW |
2 |
146,276,729 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0419:Ralgapa2
|
UTSW |
2 |
146,270,592 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0638:Ralgapa2
|
UTSW |
2 |
146,184,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0704:Ralgapa2
|
UTSW |
2 |
146,293,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0722:Ralgapa2
|
UTSW |
2 |
146,230,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0866:Ralgapa2
|
UTSW |
2 |
146,277,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1065:Ralgapa2
|
UTSW |
2 |
146,292,478 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1212:Ralgapa2
|
UTSW |
2 |
146,199,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1395:Ralgapa2
|
UTSW |
2 |
146,230,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1614:Ralgapa2
|
UTSW |
2 |
146,230,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Ralgapa2
|
UTSW |
2 |
146,199,920 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1799:Ralgapa2
|
UTSW |
2 |
146,184,648 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1905:Ralgapa2
|
UTSW |
2 |
146,229,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1956:Ralgapa2
|
UTSW |
2 |
146,302,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Ralgapa2
|
UTSW |
2 |
146,230,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2148:Ralgapa2
|
UTSW |
2 |
146,273,807 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2219:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2220:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2261:Ralgapa2
|
UTSW |
2 |
146,184,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2402:Ralgapa2
|
UTSW |
2 |
146,195,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Ralgapa2
|
UTSW |
2 |
146,203,320 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3752:Ralgapa2
|
UTSW |
2 |
146,263,551 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3953:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3956:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4177:Ralgapa2
|
UTSW |
2 |
146,327,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4182:Ralgapa2
|
UTSW |
2 |
146,277,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Ralgapa2
|
UTSW |
2 |
146,184,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4332:Ralgapa2
|
UTSW |
2 |
146,102,288 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4507:Ralgapa2
|
UTSW |
2 |
146,195,168 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4574:Ralgapa2
|
UTSW |
2 |
146,277,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4585:Ralgapa2
|
UTSW |
2 |
146,156,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4627:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4647:Ralgapa2
|
UTSW |
2 |
146,229,549 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4677:Ralgapa2
|
UTSW |
2 |
146,187,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4724:Ralgapa2
|
UTSW |
2 |
146,187,453 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4760:Ralgapa2
|
UTSW |
2 |
146,188,669 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4831:Ralgapa2
|
UTSW |
2 |
146,246,987 (GRCm39) |
intron |
probably benign |
|
|
R4962:Ralgapa2
|
UTSW |
2 |
146,276,754 (GRCm39) |
nonsense |
probably null |
|
|
R4993:Ralgapa2
|
UTSW |
2 |
146,289,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5041:Ralgapa2
|
UTSW |
2 |
146,327,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5120:Ralgapa2
|
UTSW |
2 |
146,254,004 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5185:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R5393:Ralgapa2
|
UTSW |
2 |
146,187,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5428:Ralgapa2
|
UTSW |
2 |
146,176,414 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5439:Ralgapa2
|
UTSW |
2 |
146,184,430 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5476:Ralgapa2
|
UTSW |
2 |
146,289,356 (GRCm39) |
missense |
probably benign |
|
|
R5695:Ralgapa2
|
UTSW |
2 |
146,175,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5705:Ralgapa2
|
UTSW |
2 |
146,291,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ralgapa2
|
UTSW |
2 |
146,295,326 (GRCm39) |
splice site |
probably null |
|
|
R5817:Ralgapa2
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Ralgapa2
|
UTSW |
2 |
146,230,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5994:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6048:Ralgapa2
|
UTSW |
2 |
146,276,765 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6158:Ralgapa2
|
UTSW |
2 |
146,266,596 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6169:Ralgapa2
|
UTSW |
2 |
146,292,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6280:Ralgapa2
|
UTSW |
2 |
146,184,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6301:Ralgapa2
|
UTSW |
2 |
146,169,331 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6650:Ralgapa2
|
UTSW |
2 |
146,230,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6959:Ralgapa2
|
UTSW |
2 |
146,184,621 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7020:Ralgapa2
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
R7035:Ralgapa2
|
UTSW |
2 |
146,353,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Ralgapa2
|
UTSW |
2 |
146,190,374 (GRCm39) |
missense |
probably benign |
|
|
R7186:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R7252:Ralgapa2
|
UTSW |
2 |
146,184,671 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7266:Ralgapa2
|
UTSW |
2 |
146,176,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7371:Ralgapa2
|
UTSW |
2 |
146,189,046 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7432:Ralgapa2
|
UTSW |
2 |
146,276,776 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7663:Ralgapa2
|
UTSW |
2 |
146,260,335 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7780:Ralgapa2
|
UTSW |
2 |
146,184,334 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7973:Ralgapa2
|
UTSW |
2 |
146,230,481 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8018:Ralgapa2
|
UTSW |
2 |
146,182,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8063:Ralgapa2
|
UTSW |
2 |
146,285,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8070:Ralgapa2
|
UTSW |
2 |
146,195,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8264:Ralgapa2
|
UTSW |
2 |
146,175,370 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8309:Ralgapa2
|
UTSW |
2 |
146,246,786 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8409:Ralgapa2
|
UTSW |
2 |
146,086,897 (GRCm39) |
missense |
|
|
|
R8474:Ralgapa2
|
UTSW |
2 |
146,266,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8487:Ralgapa2
|
UTSW |
2 |
146,230,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8492:Ralgapa2
|
UTSW |
2 |
146,184,524 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8733:Ralgapa2
|
UTSW |
2 |
146,266,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8856:Ralgapa2
|
UTSW |
2 |
146,184,139 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8858:Ralgapa2
|
UTSW |
2 |
146,102,285 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8862:Ralgapa2
|
UTSW |
2 |
146,266,731 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9146:Ralgapa2
|
UTSW |
2 |
146,184,252 (GRCm39) |
missense |
probably benign |
|
|
R9324:Ralgapa2
|
UTSW |
2 |
146,302,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9439:Ralgapa2
|
UTSW |
2 |
146,254,058 (GRCm39) |
missense |
probably benign |
|
|
R9457:Ralgapa2
|
UTSW |
2 |
146,176,474 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF019:Ralgapa2
|
UTSW |
2 |
146,203,423 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
X0019:Ralgapa2
|
UTSW |
2 |
146,230,572 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
Z1088:Ralgapa2
|
UTSW |
2 |
146,276,825 (GRCm39) |
missense |
probably benign |
0.20 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCACTGGTCACTGTTACTC -3'
(R):5'- GATCCGAGCAAACCTCTGTG -3'
Sequencing Primer
(F):5'- CAGTCTCTTTAGTTATCAGTCAAGGG -3'
(R):5'- CGAGCAAACCTCTGTGTGTAC -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation