Incidental Mutation 'R7483:Myo15b'
| ID |
579947 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo15b
|
| Ensembl Gene |
ENSMUSG00000034427 |
| Gene Name |
myosin XVB |
| Synonyms |
LOC217328, LOC380737, E330039G21Rik |
| MMRRC Submission |
045557-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.063)
|
| Stock # |
R7483 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
115749232-115783429 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 115749570 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 113
(E113D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091439
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000093911]
[ENSMUST00000103032]
[ENSMUST00000177736]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000091439
Gene: ENSMUSG00000034427
AA Change: E113D
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
1 |
640 |
2.4e-134 |
SMART |
|
IQ
|
660 |
682 |
1.03e1 |
SMART |
|
Pfam:MyTH4
|
837 |
945 |
2.1e-23 |
PFAM |
|
low complexity region
|
1050 |
1068 |
N/A |
INTRINSIC |
|
low complexity region
|
1136 |
1170 |
N/A |
INTRINSIC |
|
low complexity region
|
1207 |
1246 |
N/A |
INTRINSIC |
|
low complexity region
|
1302 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1468 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1509 |
N/A |
INTRINSIC |
|
SH3
|
1735 |
1792 |
1.15e-7 |
SMART |
|
Pfam:MyTH4
|
1928 |
2029 |
8.3e-25 |
PFAM |
|
B41
|
2032 |
2235 |
6.99e-4 |
SMART |
|
low complexity region
|
2243 |
2253 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103032
|
| SMART Domains |
Protein: ENSMUSP00000099321
Gene: ENSMUSG00000020782
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
24 |
60 |
9.17e1 |
SMART |
|
WD40
|
62 |
101 |
7.96e0 |
SMART |
|
Blast:WD40
|
112 |
157 |
6e-20 |
BLAST |
|
WD40
|
181 |
217 |
3.96e1 |
SMART |
|
WD40
|
221 |
258 |
5.7e1 |
SMART |
|
Pfam:LLGL
|
268 |
372 |
3.2e-47 |
PFAM |
|
WD40
|
411 |
451 |
1.38e0 |
SMART |
|
Blast:WD40
|
489 |
532 |
3e-12 |
BLAST |
|
low complexity region
|
536 |
547 |
N/A |
INTRINSIC |
|
Blast:WD40
|
576 |
615 |
2e-10 |
BLAST |
|
low complexity region
|
649 |
668 |
N/A |
INTRINSIC |
|
Blast:WD40
|
830 |
879 |
2e-10 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128826
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177736
|
| SMART Domains |
Protein: ENSMUSP00000136054
Gene: ENSMUSG00000020782
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
24 |
60 |
5.9e-1 |
SMART |
|
WD40
|
62 |
101 |
5.2e-2 |
SMART |
|
Blast:WD40
|
112 |
157 |
6e-20 |
BLAST |
|
WD40
|
181 |
217 |
2.5e-1 |
SMART |
|
WD40
|
221 |
258 |
3.6e-1 |
SMART |
|
Pfam:LLGL
|
271 |
372 |
6.2e-41 |
PFAM |
|
WD40
|
411 |
451 |
8.8e-3 |
SMART |
|
Blast:WD40
|
489 |
532 |
3e-12 |
BLAST |
|
low complexity region
|
536 |
547 |
N/A |
INTRINSIC |
|
Blast:WD40
|
576 |
615 |
2e-10 |
BLAST |
|
low complexity region
|
649 |
668 |
N/A |
INTRINSIC |
|
Blast:WD40
|
854 |
903 |
2e-10 |
BLAST |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acad10 |
A |
T |
5: 121,794,075 (GRCm39) |
|
probably null |
Het |
| Ahnak |
T |
C |
19: 8,982,186 (GRCm39) |
S1157P |
probably damaging |
Het |
| Akap12 |
T |
G |
10: 4,303,967 (GRCm39) |
V364G |
probably benign |
Het |
| Ankrd17 |
A |
G |
5: 90,447,855 (GRCm39) |
S229P |
probably benign |
Het |
| Apof |
A |
T |
10: 128,104,636 (GRCm39) |
Y5F |
probably benign |
Het |
| Arhgap24 |
T |
A |
5: 102,989,174 (GRCm39) |
M94K |
probably benign |
Het |
| Ash2l |
G |
T |
8: 26,312,798 (GRCm39) |
D479E |
probably damaging |
Het |
| Atp8a2 |
A |
T |
14: 60,245,824 (GRCm39) |
C623S |
probably benign |
Het |
| Bmper |
T |
A |
9: 23,395,238 (GRCm39) |
N656K |
probably benign |
Het |
| Braf |
T |
C |
6: 39,604,772 (GRCm39) |
I619V |
possibly damaging |
Het |
| Brwd1 |
T |
C |
16: 95,857,373 (GRCm39) |
R396G |
probably damaging |
Het |
| Car7 |
A |
T |
8: 105,276,216 (GRCm39) |
T234S |
probably benign |
Het |
| Catsper4 |
A |
T |
4: 133,945,552 (GRCm39) |
V169E |
probably damaging |
Het |
| Cemip |
T |
G |
7: 83,647,784 (GRCm39) |
I99L |
probably damaging |
Het |
| Chrna7 |
C |
A |
7: 62,754,738 (GRCm39) |
V290L |
probably damaging |
Het |
| Clip1 |
A |
T |
5: 123,755,447 (GRCm39) |
D944E |
probably benign |
Het |
| Cplane2 |
A |
G |
4: 140,947,153 (GRCm39) |
D178G |
probably damaging |
Het |
| Cyp2c68 |
T |
C |
19: 39,677,581 (GRCm39) |
T470A |
probably benign |
Het |
| Dmbx1 |
G |
T |
4: 115,780,908 (GRCm39) |
A31D |
probably damaging |
Het |
| Dnah7b |
T |
C |
1: 46,214,579 (GRCm39) |
F1115L |
probably damaging |
Het |
| Dock10 |
T |
C |
1: 80,493,283 (GRCm39) |
I1897V |
probably benign |
Het |
| Efcab3 |
A |
G |
11: 105,000,112 (GRCm39) |
I234V |
probably benign |
Het |
| Eid2b |
T |
G |
7: 27,977,243 (GRCm39) |
L13R |
probably damaging |
Het |
| Enam |
A |
G |
5: 88,649,679 (GRCm39) |
Y396C |
probably damaging |
Het |
| Fam161a |
A |
T |
11: 22,971,006 (GRCm39) |
T395S |
probably damaging |
Het |
| Fat1 |
A |
G |
8: 45,476,197 (GRCm39) |
R1748G |
probably benign |
Het |
| Fdxacb1 |
C |
A |
9: 50,681,451 (GRCm39) |
T124K |
possibly damaging |
Het |
| Fer1l6 |
A |
T |
15: 58,513,794 (GRCm39) |
D1563V |
possibly damaging |
Het |
| Gm20834 |
T |
C |
Y: 10,323,226 (GRCm39) |
H70R |
probably damaging |
Het |
| Gucy2d |
T |
A |
7: 98,098,964 (GRCm39) |
M261K |
probably damaging |
Het |
| Hcar2 |
T |
A |
5: 124,002,861 (GRCm39) |
Q214L |
probably benign |
Het |
| Hdac11 |
C |
T |
6: 91,136,214 (GRCm39) |
H75Y |
probably damaging |
Het |
| Hoxa2 |
C |
A |
6: 52,141,279 (GRCm39) |
A116S |
probably benign |
Het |
| Ints2 |
A |
G |
11: 86,106,444 (GRCm39) |
C989R |
probably damaging |
Het |
| Jpt1 |
T |
C |
11: 115,393,950 (GRCm39) |
E36G |
probably damaging |
Het |
| Kdm5d |
G |
A |
Y: 914,044 (GRCm39) |
R327Q |
possibly damaging |
Het |
| Klhl1 |
T |
C |
14: 96,584,304 (GRCm39) |
M309V |
probably benign |
Het |
| Larp4 |
A |
G |
15: 99,889,659 (GRCm39) |
K193E |
probably benign |
Het |
| Lmo3 |
C |
T |
6: 138,393,500 (GRCm39) |
C40Y |
probably damaging |
Het |
| Mcm4 |
A |
G |
16: 15,448,306 (GRCm39) |
V417A |
probably benign |
Het |
| Med8 |
A |
G |
4: 118,268,176 (GRCm39) |
E34G |
probably damaging |
Het |
| Mex3b |
G |
T |
7: 82,517,114 (GRCm39) |
A86S |
possibly damaging |
Het |
| Muc6 |
T |
C |
7: 141,224,245 (GRCm39) |
T1646A |
unknown |
Het |
| Myo7a |
T |
A |
7: 97,712,881 (GRCm39) |
H1698L |
probably benign |
Het |
| Myocos |
T |
A |
1: 162,484,678 (GRCm39) |
M44L |
unknown |
Het |
| Nalcn |
A |
G |
14: 123,551,499 (GRCm39) |
V1036A |
probably damaging |
Het |
| Nfrkb |
C |
T |
9: 31,325,328 (GRCm39) |
Q924* |
probably null |
Het |
| Nol6 |
A |
G |
4: 41,117,424 (GRCm39) |
L923P |
possibly damaging |
Het |
| Nrxn3 |
T |
C |
12: 89,477,232 (GRCm39) |
Y472H |
probably damaging |
Het |
| Nudcd1 |
A |
G |
15: 44,269,253 (GRCm39) |
Y136H |
possibly damaging |
Het |
| Obox2 |
T |
C |
7: 15,131,241 (GRCm39) |
C116R |
probably damaging |
Het |
| Onecut3 |
A |
T |
10: 80,331,310 (GRCm39) |
S157C |
unknown |
Het |
| Or10ak11 |
A |
G |
4: 118,687,517 (GRCm39) |
V39A |
probably damaging |
Het |
| Or11g27 |
T |
A |
14: 50,771,472 (GRCm39) |
V201D |
probably benign |
Het |
| Or2d2b |
T |
A |
7: 106,705,982 (GRCm39) |
I29F |
probably benign |
Het |
| Or4f15 |
T |
C |
2: 111,814,124 (GRCm39) |
I98M |
probably damaging |
Het |
| Oscp1 |
C |
T |
4: 125,967,726 (GRCm39) |
R91* |
probably null |
Het |
| Pclo |
A |
T |
5: 14,762,606 (GRCm39) |
D408V |
|
Het |
| Pde8a |
T |
C |
7: 80,932,581 (GRCm39) |
V81A |
probably benign |
Het |
| Pde8b |
T |
A |
13: 95,164,251 (GRCm39) |
D653V |
probably damaging |
Het |
| Peg10 |
T |
TCCG |
6: 4,756,451 (GRCm39) |
|
probably benign |
Het |
| Pik3cg |
T |
C |
12: 32,245,647 (GRCm39) |
Y867C |
probably damaging |
Het |
| Pkd1l3 |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
8: 110,350,827 (GRCm39) |
|
probably benign |
Het |
| Psd4 |
A |
T |
2: 24,294,768 (GRCm39) |
D776V |
possibly damaging |
Het |
| Ptprb |
A |
G |
10: 116,119,334 (GRCm39) |
E156G |
probably benign |
Het |
| Rad54b |
A |
G |
4: 11,610,372 (GRCm39) |
Y663C |
probably damaging |
Het |
| Ranbp3l |
T |
A |
15: 9,030,955 (GRCm39) |
V78D |
possibly damaging |
Het |
| Rbm12 |
T |
C |
2: 155,940,138 (GRCm39) |
I45V |
unknown |
Het |
| Scn9a |
A |
G |
2: 66,363,692 (GRCm39) |
V862A |
probably damaging |
Het |
| Sdcbp |
T |
C |
4: 6,393,089 (GRCm39) |
I242T |
possibly damaging |
Het |
| Slc25a24 |
A |
G |
3: 109,066,751 (GRCm39) |
T302A |
probably damaging |
Het |
| Slc45a3 |
G |
T |
1: 131,904,549 (GRCm39) |
|
probably benign |
Het |
| Srpk1 |
T |
C |
17: 28,813,192 (GRCm39) |
I517M |
probably benign |
Het |
| Tmx4 |
A |
G |
2: 134,481,581 (GRCm39) |
M114T |
probably benign |
Het |
| Trhr |
T |
A |
15: 44,092,627 (GRCm39) |
V288D |
probably damaging |
Het |
| Tspoap1 |
A |
T |
11: 87,652,351 (GRCm39) |
I42F |
probably benign |
Het |
| Ttn |
A |
T |
2: 76,781,856 (GRCm39) |
D1063E |
unknown |
Het |
| Tusc3 |
A |
G |
8: 39,538,635 (GRCm39) |
I225V |
probably benign |
Het |
| Ugt2b38 |
A |
G |
5: 87,571,973 (GRCm39) |
S20P |
probably damaging |
Het |
| Upf2 |
A |
G |
2: 6,032,219 (GRCm39) |
T922A |
unknown |
Het |
| Usp38 |
C |
T |
8: 81,741,190 (GRCm39) |
|
probably benign |
Het |
| Vmn1r216 |
A |
G |
13: 23,283,738 (GRCm39) |
I140M |
probably damaging |
Het |
| Vmn2r115 |
T |
A |
17: 23,565,371 (GRCm39) |
N419K |
possibly damaging |
Het |
| Vmn2r55 |
C |
T |
7: 12,404,755 (GRCm39) |
G216D |
probably benign |
Het |
| Vwa8 |
A |
C |
14: 79,219,674 (GRCm39) |
|
probably null |
Het |
| Wnt7b |
C |
A |
15: 85,421,615 (GRCm39) |
R349L |
possibly damaging |
Het |
| Xbp1 |
T |
C |
11: 5,471,098 (GRCm39) |
V35A |
probably benign |
Het |
| Zan |
A |
T |
5: 137,445,057 (GRCm39) |
M1734K |
unknown |
Het |
| Zfhx4 |
A |
G |
3: 5,477,237 (GRCm39) |
E3284G |
probably damaging |
Het |
| Zfp458 |
A |
G |
13: 67,404,978 (GRCm39) |
L487S |
possibly damaging |
Het |
| Zfp687 |
C |
T |
3: 94,914,841 (GRCm39) |
R1220H |
probably damaging |
Het |
| Zp1 |
A |
G |
19: 10,895,280 (GRCm39) |
L324P |
possibly damaging |
Het |
|
| Other mutations in Myo15b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00556:Myo15b
|
APN |
11 |
115,782,742 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01409:Myo15b
|
APN |
11 |
115,760,330 (GRCm39) |
nonsense |
probably null |
|
|
IGL01539:Myo15b
|
APN |
11 |
115,754,299 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL01895:Myo15b
|
APN |
11 |
115,774,324 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02254:Myo15b
|
APN |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02343:Myo15b
|
APN |
11 |
115,764,226 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02349:Myo15b
|
APN |
11 |
115,753,931 (GRCm39) |
splice site |
probably benign |
|
|
IGL02368:Myo15b
|
APN |
11 |
115,767,828 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02576:Myo15b
|
APN |
11 |
115,780,879 (GRCm39) |
missense |
probably null |
0.97 |
|
IGL02650:Myo15b
|
APN |
11 |
115,777,337 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02661:Myo15b
|
APN |
11 |
115,774,895 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02716:Myo15b
|
APN |
11 |
115,774,535 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02733:Myo15b
|
APN |
11 |
115,775,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02951:Myo15b
|
APN |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03017:Myo15b
|
APN |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03029:Myo15b
|
APN |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
ANU74:Myo15b
|
UTSW |
11 |
115,769,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0092:Myo15b
|
UTSW |
11 |
115,753,812 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0255:Myo15b
|
UTSW |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0325:Myo15b
|
UTSW |
11 |
115,775,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0614:Myo15b
|
UTSW |
11 |
115,773,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0652:Myo15b
|
UTSW |
11 |
115,755,468 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0711:Myo15b
|
UTSW |
11 |
115,774,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0815:Myo15b
|
UTSW |
11 |
115,757,162 (GRCm39) |
splice site |
probably benign |
|
|
R0961:Myo15b
|
UTSW |
11 |
115,773,280 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1066:Myo15b
|
UTSW |
11 |
115,770,577 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1221:Myo15b
|
UTSW |
11 |
115,777,546 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1240:Myo15b
|
UTSW |
11 |
115,771,327 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1275:Myo15b
|
UTSW |
11 |
115,774,318 (GRCm39) |
small deletion |
probably benign |
|
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1317:Myo15b
|
UTSW |
11 |
115,774,460 (GRCm39) |
missense |
probably null |
0.14 |
|
R1491:Myo15b
|
UTSW |
11 |
115,777,683 (GRCm39) |
splice site |
probably null |
|
|
R1552:Myo15b
|
UTSW |
11 |
115,757,461 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1731:Myo15b
|
UTSW |
11 |
115,782,386 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R1800:Myo15b
|
UTSW |
11 |
115,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1843:Myo15b
|
UTSW |
11 |
115,760,412 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1894:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1917:Myo15b
|
UTSW |
11 |
115,773,080 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1934:Myo15b
|
UTSW |
11 |
115,754,310 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1939:Myo15b
|
UTSW |
11 |
115,778,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1945:Myo15b
|
UTSW |
11 |
115,769,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1986:Myo15b
|
UTSW |
11 |
115,773,701 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2130:Myo15b
|
UTSW |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2138:Myo15b
|
UTSW |
11 |
115,774,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2176:Myo15b
|
UTSW |
11 |
115,757,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2415:Myo15b
|
UTSW |
11 |
115,770,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2483:Myo15b
|
UTSW |
11 |
115,755,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3620:Myo15b
|
UTSW |
11 |
115,762,013 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3716:Myo15b
|
UTSW |
11 |
115,754,239 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4013:Myo15b
|
UTSW |
11 |
115,762,282 (GRCm39) |
nonsense |
probably null |
|
|
R4021:Myo15b
|
UTSW |
11 |
115,764,331 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4119:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4120:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4499:Myo15b
|
UTSW |
11 |
115,781,778 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4653:Myo15b
|
UTSW |
11 |
115,770,813 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4655:Myo15b
|
UTSW |
11 |
115,781,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Myo15b
|
UTSW |
11 |
115,752,761 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4702:Myo15b
|
UTSW |
11 |
115,774,834 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4777:Myo15b
|
UTSW |
11 |
115,770,478 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4833:Myo15b
|
UTSW |
11 |
115,778,428 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5083:Myo15b
|
UTSW |
11 |
115,757,482 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5121:Myo15b
|
UTSW |
11 |
115,776,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5146:Myo15b
|
UTSW |
11 |
115,782,024 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5535:Myo15b
|
UTSW |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5647:Myo15b
|
UTSW |
11 |
115,762,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5849:Myo15b
|
UTSW |
11 |
115,772,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5882:Myo15b
|
UTSW |
11 |
115,760,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5956:Myo15b
|
UTSW |
11 |
115,764,583 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6273:Myo15b
|
UTSW |
11 |
115,753,625 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6302:Myo15b
|
UTSW |
11 |
115,777,065 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6318:Myo15b
|
UTSW |
11 |
115,781,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6462:Myo15b
|
UTSW |
11 |
115,750,268 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6792:Myo15b
|
UTSW |
11 |
115,775,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Myo15b
|
UTSW |
11 |
115,781,540 (GRCm39) |
splice site |
probably null |
|
|
R7015:Myo15b
|
UTSW |
11 |
115,762,670 (GRCm39) |
missense |
|
|
|
R7020:Myo15b
|
UTSW |
11 |
115,757,493 (GRCm39) |
nonsense |
probably null |
|
|
R7096:Myo15b
|
UTSW |
11 |
115,782,324 (GRCm39) |
splice site |
probably null |
|
|
R7219:Myo15b
|
UTSW |
11 |
115,767,921 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7400:Myo15b
|
UTSW |
11 |
115,750,939 (GRCm39) |
missense |
|
|
|
R7413:Myo15b
|
UTSW |
11 |
115,768,970 (GRCm39) |
missense |
|
|
|
R7523:Myo15b
|
UTSW |
11 |
115,781,684 (GRCm39) |
missense |
unknown |
|
|
R7737:Myo15b
|
UTSW |
11 |
115,778,749 (GRCm39) |
missense |
unknown |
|
|
R7784:Myo15b
|
UTSW |
11 |
115,752,166 (GRCm39) |
missense |
|
|
|
R7842:Myo15b
|
UTSW |
11 |
115,762,321 (GRCm39) |
missense |
|
|
|
R7921:Myo15b
|
UTSW |
11 |
115,778,004 (GRCm39) |
nonsense |
probably null |
|
|
R8065:Myo15b
|
UTSW |
11 |
115,778,769 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8183:Myo15b
|
UTSW |
11 |
115,773,843 (GRCm39) |
splice site |
probably null |
|
|
R8193:Myo15b
|
UTSW |
11 |
115,775,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8237:Myo15b
|
UTSW |
11 |
115,767,827 (GRCm39) |
missense |
|
|
|
R8430:Myo15b
|
UTSW |
11 |
115,773,049 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8482:Myo15b
|
UTSW |
11 |
115,774,083 (GRCm39) |
nonsense |
probably null |
|
|
R8515:Myo15b
|
UTSW |
11 |
115,749,610 (GRCm39) |
missense |
|
|
|
R8798:Myo15b
|
UTSW |
11 |
115,754,232 (GRCm39) |
missense |
|
|
|
R8937:Myo15b
|
UTSW |
11 |
115,773,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8975:Myo15b
|
UTSW |
11 |
115,781,780 (GRCm39) |
missense |
unknown |
|
|
R9045:Myo15b
|
UTSW |
11 |
115,783,178 (GRCm39) |
makesense |
probably null |
|
|
R9117:Myo15b
|
UTSW |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9185:Myo15b
|
UTSW |
11 |
115,771,255 (GRCm39) |
missense |
unknown |
|
|
R9226:Myo15b
|
UTSW |
11 |
115,750,924 (GRCm39) |
missense |
|
|
|
R9302:Myo15b
|
UTSW |
11 |
115,776,238 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9318:Myo15b
|
UTSW |
11 |
115,775,965 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9336:Myo15b
|
UTSW |
11 |
115,771,064 (GRCm39) |
missense |
|
|
|
R9337:Myo15b
|
UTSW |
11 |
115,749,861 (GRCm39) |
missense |
|
|
|
R9338:Myo15b
|
UTSW |
11 |
115,762,238 (GRCm39) |
missense |
|
|
|
R9498:Myo15b
|
UTSW |
11 |
115,770,784 (GRCm39) |
missense |
|
|
|
R9500:Myo15b
|
UTSW |
11 |
115,777,466 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9602:Myo15b
|
UTSW |
11 |
115,769,269 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9642:Myo15b
|
UTSW |
11 |
115,772,335 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0020:Myo15b
|
UTSW |
11 |
115,762,625 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,778,751 (GRCm39) |
missense |
unknown |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,774,278 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGACATCGGGAAGTCAGTC -3'
(R):5'- TTCTGACCTGGGATCCGAAG -3'
Sequencing Primer
(F):5'- TCGGGAAGTCAGTCATGGGC -3'
(R):5'- CCATTTTGGGTGGCCGCTC -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation