Incidental Mutation 'R7486:Med13l'
| ID |
580156 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Med13l
|
| Ensembl Gene |
ENSMUSG00000018076 |
| Gene Name |
mediator complex subunit 13-like |
| Synonyms |
9030618F05Rik, Trap240L, 6330591G05Rik, Thrap2, 2210413I17Rik |
| MMRRC Submission |
045560-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.966)
|
| Stock # |
R7486 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
118698744-118903503 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 118866539 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 531
(T531I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000098379
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100816]
[ENSMUST00000201010]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100816
AA Change: T531I
PolyPhen 2
Score 0.170 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000098379
Gene: ENSMUSG00000018076
AA Change: T531I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med13_N
|
1 |
380 |
2.5e-116 |
PFAM |
|
low complexity region
|
442 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1031 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1541 |
1593 |
N/A |
INTRINSIC |
|
low complexity region
|
1601 |
1611 |
N/A |
INTRINSIC |
|
Pfam:Med13_C
|
1675 |
2197 |
1e-142 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201010
AA Change: T531I
PolyPhen 2
Score 0.293 (Sensitivity: 0.91; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000144092
Gene: ENSMUSG00000018076
AA Change: T531I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Med13_N
|
1 |
380 |
1e-112 |
PFAM |
|
low complexity region
|
442 |
460 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
1020 |
1031 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1541 |
1593 |
N/A |
INTRINSIC |
|
low complexity region
|
1601 |
1611 |
N/A |
INTRINSIC |
|
Pfam:Med13_C
|
1675 |
2206 |
1.7e-138 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam21 |
T |
C |
12: 81,605,657 (GRCm39) |
I702V |
probably benign |
Het |
| Adgre5 |
T |
C |
8: 84,450,515 (GRCm39) |
E815G |
probably damaging |
Het |
| Adgrl2 |
A |
G |
3: 148,523,330 (GRCm39) |
V298A |
|
Het |
| Akp3 |
A |
G |
1: 87,053,201 (GRCm39) |
D91G |
probably damaging |
Het |
| Ano8 |
A |
G |
8: 71,937,642 (GRCm39) |
|
probably null |
Het |
| Blvra |
T |
C |
2: 126,929,243 (GRCm39) |
S136P |
unknown |
Het |
| Cacul1 |
T |
A |
19: 60,568,868 (GRCm39) |
M97L |
probably benign |
Het |
| Ccdc80 |
T |
C |
16: 44,946,542 (GRCm39) |
V827A |
probably damaging |
Het |
| Cep68 |
T |
C |
11: 20,192,166 (GRCm39) |
E11G |
probably benign |
Het |
| Cfap221 |
A |
T |
1: 119,851,322 (GRCm39) |
V813E |
possibly damaging |
Het |
| Chd6 |
A |
G |
2: 160,791,923 (GRCm39) |
V2478A |
probably damaging |
Het |
| Chmp6 |
T |
C |
11: 119,807,783 (GRCm39) |
F148S |
probably benign |
Het |
| Clca3a2 |
T |
A |
3: 144,503,362 (GRCm39) |
I863F |
probably damaging |
Het |
| Cnnm2 |
T |
C |
19: 46,750,513 (GRCm39) |
V101A |
possibly damaging |
Het |
| Cpne8 |
A |
T |
15: 90,400,109 (GRCm39) |
|
probably null |
Het |
| Dmbt1 |
T |
G |
7: 130,668,192 (GRCm39) |
C483G |
unknown |
Het |
| Dnah7b |
G |
A |
1: 46,329,894 (GRCm39) |
G3246D |
probably damaging |
Het |
| Dnajc3 |
C |
A |
14: 119,209,816 (GRCm39) |
T297K |
probably benign |
Het |
| Dpm3 |
A |
G |
3: 89,174,034 (GRCm39) |
|
probably null |
Het |
| Eef2k |
A |
G |
7: 120,457,793 (GRCm39) |
N51D |
probably benign |
Het |
| Erc1 |
G |
A |
6: 119,571,907 (GRCm39) |
Q1022* |
probably null |
Het |
| Ercc5 |
T |
A |
1: 44,187,224 (GRCm39) |
M1K |
probably null |
Het |
| Fam114a2 |
C |
T |
11: 57,404,515 (GRCm39) |
G83D |
probably damaging |
Het |
| Fat4 |
C |
A |
3: 39,011,576 (GRCm39) |
Y2225* |
probably null |
Het |
| Frk |
G |
A |
10: 34,423,292 (GRCm39) |
W123* |
probably null |
Het |
| Gm11568 |
T |
A |
11: 99,749,292 (GRCm39) |
C166S |
unknown |
Het |
| Gpr153 |
A |
G |
4: 152,366,858 (GRCm39) |
D337G |
probably benign |
Het |
| Gpt2 |
T |
C |
8: 86,252,235 (GRCm39) |
F517L |
probably damaging |
Het |
| Gsg1 |
C |
T |
6: 135,214,427 (GRCm39) |
E361K |
probably benign |
Het |
| Hsfy2 |
G |
A |
1: 56,676,130 (GRCm39) |
R136* |
probably null |
Het |
| Insm1 |
G |
A |
2: 146,065,738 (GRCm39) |
R518H |
probably damaging |
Het |
| Kank1 |
G |
A |
19: 25,388,193 (GRCm39) |
C622Y |
probably damaging |
Het |
| Katnb1 |
T |
A |
8: 95,825,357 (GRCm39) |
S640R |
probably damaging |
Het |
| Kcnmb4 |
A |
G |
10: 116,254,180 (GRCm39) |
V199A |
probably benign |
Het |
| Lamb1 |
T |
G |
12: 31,337,441 (GRCm39) |
S391A |
probably benign |
Het |
| Larp7-ps |
A |
T |
4: 92,079,506 (GRCm39) |
V105E |
probably benign |
Het |
| Macf1 |
T |
G |
4: 123,303,374 (GRCm39) |
D376A |
probably benign |
Het |
| Map7d1 |
C |
A |
4: 126,128,179 (GRCm39) |
R614L |
unknown |
Het |
| Mcm8 |
C |
T |
2: 132,681,440 (GRCm39) |
R667W |
probably damaging |
Het |
| Mstn |
G |
T |
1: 53,103,128 (GRCm39) |
A155S |
probably damaging |
Het |
| Mycbp2 |
C |
T |
14: 103,434,690 (GRCm39) |
R2251K |
probably damaging |
Het |
| Myo19 |
T |
C |
11: 84,796,463 (GRCm39) |
S692P |
probably benign |
Het |
| Nipbl |
A |
T |
15: 8,325,120 (GRCm39) |
N2514K |
probably benign |
Het |
| Nkd2 |
T |
A |
13: 73,995,561 (GRCm39) |
|
probably benign |
Het |
| Nox3 |
T |
A |
17: 3,720,219 (GRCm39) |
Y322F |
probably damaging |
Het |
| Nt5dc1 |
A |
G |
10: 34,275,805 (GRCm39) |
Y135H |
probably benign |
Het |
| Oog3 |
T |
A |
4: 143,884,742 (GRCm39) |
H398L |
probably benign |
Het |
| Or10g9 |
T |
A |
9: 39,912,181 (GRCm39) |
Y114F |
probably benign |
Het |
| Or12j4 |
C |
T |
7: 140,045,947 (GRCm39) |
|
probably benign |
Het |
| Or1e29 |
T |
C |
11: 73,667,847 (GRCm39) |
Y102C |
probably damaging |
Het |
| Otogl |
A |
G |
10: 107,657,849 (GRCm39) |
L1027P |
probably damaging |
Het |
| Pcdh20 |
T |
A |
14: 88,706,050 (GRCm39) |
I417F |
possibly damaging |
Het |
| Pcdha12 |
T |
A |
18: 37,154,610 (GRCm39) |
V443E |
probably damaging |
Het |
| Pcdhga2 |
A |
G |
18: 37,803,461 (GRCm39) |
D435G |
probably benign |
Het |
| Pcnt |
G |
T |
10: 76,254,270 (GRCm39) |
T853K |
probably benign |
Het |
| Pcnt |
T |
C |
10: 76,254,271 (GRCm39) |
T853A |
probably benign |
Het |
| Pgghg |
T |
A |
7: 140,522,393 (GRCm39) |
S57R |
probably benign |
Het |
| Ppm1m |
T |
C |
9: 106,073,810 (GRCm39) |
D301G |
probably damaging |
Het |
| Ppp6r1 |
A |
G |
7: 4,642,899 (GRCm39) |
V519A |
probably benign |
Het |
| Prss41 |
ACAGCAGCAGCAGCAGCAGCA |
ACAGCAGCAGCAGCAGCA |
17: 24,063,072 (GRCm39) |
|
probably benign |
Het |
| Rasa3 |
C |
T |
8: 13,640,201 (GRCm39) |
|
probably null |
Het |
| Robo4 |
T |
C |
9: 37,316,870 (GRCm39) |
V395A |
probably damaging |
Het |
| Scrib |
A |
G |
15: 75,929,499 (GRCm39) |
S1123P |
probably damaging |
Het |
| Setd1b |
A |
G |
5: 123,301,655 (GRCm39) |
K45E |
probably benign |
Het |
| Slc14a1 |
T |
C |
18: 78,154,739 (GRCm39) |
S216G |
probably benign |
Het |
| Slc25a45 |
A |
G |
19: 5,934,997 (GRCm39) |
Y282C |
probably damaging |
Het |
| Slc6a5 |
T |
C |
7: 49,567,078 (GRCm39) |
S255P |
possibly damaging |
Het |
| Smc2 |
A |
T |
4: 52,462,861 (GRCm39) |
Q617L |
possibly damaging |
Het |
| Spo11 |
G |
A |
2: 172,825,870 (GRCm39) |
D103N |
probably benign |
Het |
| Tcf20 |
A |
T |
15: 82,737,935 (GRCm39) |
M1172K |
possibly damaging |
Het |
| Tesc |
T |
A |
5: 118,184,382 (GRCm39) |
S21T |
probably benign |
Het |
| Tie1 |
C |
A |
4: 118,337,101 (GRCm39) |
|
probably null |
Het |
| Trim24 |
T |
G |
6: 37,934,774 (GRCm39) |
|
probably null |
Het |
| Trpm7 |
A |
G |
2: 126,673,115 (GRCm39) |
|
probably null |
Het |
| Unc13d |
T |
C |
11: 115,965,259 (GRCm39) |
D193G |
possibly damaging |
Het |
| Upk3a |
A |
T |
15: 84,902,225 (GRCm39) |
|
probably null |
Het |
| Vmn2r25 |
T |
C |
6: 123,800,101 (GRCm39) |
N747S |
probably damaging |
Het |
| Wipf1 |
GCCTCCTCCTCCTCCTCCTCCTCC |
GCCTCCTCCTCCTCCTCCTCC |
2: 73,270,418 (GRCm39) |
|
probably benign |
Het |
| Zbtb2 |
G |
A |
10: 4,319,025 (GRCm39) |
Q334* |
probably null |
Het |
| Zfp653 |
T |
C |
9: 21,967,824 (GRCm39) |
N494D |
probably damaging |
Het |
| Zfp865 |
A |
G |
7: 5,034,259 (GRCm39) |
D748G |
possibly damaging |
Het |
| Zzef1 |
T |
C |
11: 72,755,612 (GRCm39) |
S1014P |
possibly damaging |
Het |
|
| Other mutations in Med13l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Med13l
|
APN |
5 |
118,862,136 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01012:Med13l
|
APN |
5 |
118,872,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01316:Med13l
|
APN |
5 |
118,900,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01529:Med13l
|
APN |
5 |
118,880,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01731:Med13l
|
APN |
5 |
118,880,472 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01790:Med13l
|
APN |
5 |
118,731,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02394:Med13l
|
APN |
5 |
118,886,898 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL02432:Med13l
|
APN |
5 |
118,876,465 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02698:Med13l
|
APN |
5 |
118,900,894 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02801:Med13l
|
APN |
5 |
118,883,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03242:Med13l
|
APN |
5 |
118,885,510 (GRCm39) |
missense |
probably benign |
|
|
IGL03270:Med13l
|
APN |
5 |
118,869,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Basics
|
UTSW |
5 |
118,897,329 (GRCm39) |
critical splice donor site |
probably null |
|
|
firmament
|
UTSW |
5 |
118,883,071 (GRCm39) |
splice site |
probably null |
|
|
Fundament
|
UTSW |
5 |
118,859,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Root
|
UTSW |
5 |
118,731,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0035:Med13l
|
UTSW |
5 |
118,880,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0051:Med13l
|
UTSW |
5 |
118,880,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0051:Med13l
|
UTSW |
5 |
118,880,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0136:Med13l
|
UTSW |
5 |
118,862,115 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0158:Med13l
|
UTSW |
5 |
118,880,514 (GRCm39) |
missense |
unknown |
|
|
R0197:Med13l
|
UTSW |
5 |
118,809,067 (GRCm39) |
splice site |
probably benign |
|
|
R0370:Med13l
|
UTSW |
5 |
118,879,891 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0492:Med13l
|
UTSW |
5 |
118,876,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Med13l
|
UTSW |
5 |
118,897,188 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0726:Med13l
|
UTSW |
5 |
118,886,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0738:Med13l
|
UTSW |
5 |
118,889,698 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0827:Med13l
|
UTSW |
5 |
118,864,312 (GRCm39) |
splice site |
probably benign |
|
|
R0883:Med13l
|
UTSW |
5 |
118,809,067 (GRCm39) |
splice site |
probably benign |
|
|
R0959:Med13l
|
UTSW |
5 |
118,892,350 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1458:Med13l
|
UTSW |
5 |
118,876,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1562:Med13l
|
UTSW |
5 |
118,876,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1577:Med13l
|
UTSW |
5 |
118,859,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1661:Med13l
|
UTSW |
5 |
118,887,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1665:Med13l
|
UTSW |
5 |
118,887,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1720:Med13l
|
UTSW |
5 |
118,880,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1929:Med13l
|
UTSW |
5 |
118,866,898 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1967:Med13l
|
UTSW |
5 |
118,899,387 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2301:Med13l
|
UTSW |
5 |
118,731,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3691:Med13l
|
UTSW |
5 |
118,859,562 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3895:Med13l
|
UTSW |
5 |
118,899,388 (GRCm39) |
missense |
probably null |
0.99 |
|
R4043:Med13l
|
UTSW |
5 |
118,731,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4593:Med13l
|
UTSW |
5 |
118,880,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Med13l
|
UTSW |
5 |
118,883,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4995:Med13l
|
UTSW |
5 |
118,869,014 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5010:Med13l
|
UTSW |
5 |
118,731,615 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5057:Med13l
|
UTSW |
5 |
118,856,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5369:Med13l
|
UTSW |
5 |
118,862,075 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5446:Med13l
|
UTSW |
5 |
118,880,462 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5564:Med13l
|
UTSW |
5 |
118,880,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Med13l
|
UTSW |
5 |
118,866,730 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5580:Med13l
|
UTSW |
5 |
118,889,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5634:Med13l
|
UTSW |
5 |
118,698,915 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5748:Med13l
|
UTSW |
5 |
118,731,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5764:Med13l
|
UTSW |
5 |
118,866,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5765:Med13l
|
UTSW |
5 |
118,866,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6083:Med13l
|
UTSW |
5 |
118,859,551 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6504:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6546:Med13l
|
UTSW |
5 |
118,859,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6797:Med13l
|
UTSW |
5 |
118,897,329 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6911:Med13l
|
UTSW |
5 |
118,893,723 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6942:Med13l
|
UTSW |
5 |
118,883,071 (GRCm39) |
splice site |
probably null |
|
|
R7018:Med13l
|
UTSW |
5 |
118,890,051 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7096:Med13l
|
UTSW |
5 |
118,859,991 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7113:Med13l
|
UTSW |
5 |
118,864,330 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7136:Med13l
|
UTSW |
5 |
118,859,587 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7140:Med13l
|
UTSW |
5 |
118,880,037 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7345:Med13l
|
UTSW |
5 |
118,880,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7409:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7410:Med13l
|
UTSW |
5 |
118,698,897 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7432:Med13l
|
UTSW |
5 |
118,890,003 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7509:Med13l
|
UTSW |
5 |
118,886,995 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7722:Med13l
|
UTSW |
5 |
118,885,472 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7802:Med13l
|
UTSW |
5 |
118,866,655 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8081:Med13l
|
UTSW |
5 |
118,866,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Med13l
|
UTSW |
5 |
118,886,794 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8266:Med13l
|
UTSW |
5 |
118,880,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8347:Med13l
|
UTSW |
5 |
118,880,662 (GRCm39) |
missense |
probably benign |
|
|
R8365:Med13l
|
UTSW |
5 |
118,866,709 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8508:Med13l
|
UTSW |
5 |
118,892,386 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8920:Med13l
|
UTSW |
5 |
118,885,543 (GRCm39) |
nonsense |
probably null |
|
|
R8970:Med13l
|
UTSW |
5 |
118,883,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8994:Med13l
|
UTSW |
5 |
118,866,226 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9045:Med13l
|
UTSW |
5 |
118,880,816 (GRCm39) |
missense |
probably benign |
|
|
R9401:Med13l
|
UTSW |
5 |
118,883,089 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9445:Med13l
|
UTSW |
5 |
118,862,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9446:Med13l
|
UTSW |
5 |
118,876,567 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9714:Med13l
|
UTSW |
5 |
118,866,438 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9777:Med13l
|
UTSW |
5 |
118,887,024 (GRCm39) |
missense |
probably benign |
|
|
R9781:Med13l
|
UTSW |
5 |
118,868,032 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R9797:Med13l
|
UTSW |
5 |
118,880,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0065:Med13l
|
UTSW |
5 |
118,867,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Med13l
|
UTSW |
5 |
118,887,706 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAAAGAGACCCTTGGTGCC -3'
(R):5'- TACAAGGCTGTCTCACTGGC -3'
Sequencing Primer
(F):5'- AAAGAGACCCTTGGTGCCCTTTC -3'
(R):5'- CCTCTATAGTAGACAGCTGCTGAAG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation