Incidental Mutation 'R7492:Ablim2'
| ID |
580831 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ablim2
|
| Ensembl Gene |
ENSMUSG00000029095 |
| Gene Name |
actin-binding LIM protein 2 |
| Synonyms |
|
| MMRRC Submission |
045566-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.156)
|
| Stock # |
R7492 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
35915224-36042317 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 35998673 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 367
(S367G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000050571
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000054598]
[ENSMUST00000101280]
[ENSMUST00000114203]
[ENSMUST00000114204]
[ENSMUST00000114205]
[ENSMUST00000114206]
[ENSMUST00000114210]
[ENSMUST00000129347]
[ENSMUST00000130233]
|
| AlphaFold |
Q8BL65 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000054598
AA Change: S367G
PolyPhen 2
Score 0.140 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000050571
Gene: ENSMUSG00000029095
AA Change: S367G
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
373 |
N/A |
INTRINSIC |
|
low complexity region
|
477 |
489 |
N/A |
INTRINSIC |
|
VHP
|
577 |
612 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101280
AA Change: S386G
PolyPhen 2
Score 0.022 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000098838
Gene: ENSMUSG00000029095
AA Change: S386G
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
297 |
315 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
392 |
N/A |
INTRINSIC |
|
low complexity region
|
511 |
523 |
N/A |
INTRINSIC |
|
VHP
|
572 |
607 |
2.34e-19 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114203
AA Change: S135G
PolyPhen 2
Score 0.576 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000109841
Gene: ENSMUSG00000029095
AA Change: S135G
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1WIG|A
|
1 |
28 |
5e-13 |
PDB |
|
low complexity region
|
35 |
53 |
N/A |
INTRINSIC |
|
low complexity region
|
132 |
141 |
N/A |
INTRINSIC |
|
low complexity region
|
211 |
223 |
N/A |
INTRINSIC |
|
VHP
|
311 |
346 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114204
AA Change: S367G
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000109842
Gene: ENSMUSG00000029095
AA Change: S367G
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
373 |
N/A |
INTRINSIC |
|
low complexity region
|
510 |
522 |
N/A |
INTRINSIC |
|
VHP
|
571 |
606 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114205
AA Change: S367G
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000109843
Gene: ENSMUSG00000029095
AA Change: S367G
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
373 |
N/A |
INTRINSIC |
|
low complexity region
|
477 |
489 |
N/A |
INTRINSIC |
|
VHP
|
538 |
573 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114206
AA Change: S378G
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000109844
Gene: ENSMUSG00000029095
AA Change: S378G
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
521 |
533 |
N/A |
INTRINSIC |
|
VHP
|
582 |
617 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114210
AA Change: S367G
PolyPhen 2
Score 0.115 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000109848
Gene: ENSMUSG00000029095
AA Change: S367G
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
low complexity region
|
278 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
373 |
N/A |
INTRINSIC |
|
low complexity region
|
510 |
522 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125378
|
| SMART Domains |
Protein: ENSMUSP00000115931
Gene: ENSMUSG00000029095
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AbLIM_anchor
|
1 |
115 |
6.3e-29 |
PFAM |
|
low complexity region
|
136 |
148 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129347
AA Change: S386G
PolyPhen 2
Score 0.026 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000123525
Gene: ENSMUSG00000029095
AA Change: S386G
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
23 |
74 |
2.76e-8 |
SMART |
|
LIM
|
82 |
134 |
1.26e-11 |
SMART |
|
LIM
|
152 |
203 |
9.6e-17 |
SMART |
|
LIM
|
211 |
263 |
4.96e-10 |
SMART |
|
Pfam:AbLIM_anchor
|
295 |
513 |
2.1e-78 |
PFAM |
|
Pfam:AbLIM_anchor
|
497 |
628 |
2.6e-37 |
PFAM |
|
VHP
|
629 |
664 |
2.34e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130233
AA Change: S154G
PolyPhen 2
Score 0.140 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000118159
Gene: ENSMUSG00000029095
AA Change: S154G
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:LIM
|
1 |
20 |
3e-6 |
BLAST |
|
PDB:1WIG|A
|
1 |
28 |
7e-13 |
PDB |
|
low complexity region
|
54 |
72 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
160 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000114616
Gene: ENSMUSG00000029095
AA Change: S102G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AbLIM_anchor
|
12 |
164 |
4.3e-55 |
PFAM |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000123616
Gene: ENSMUSG00000029095
AA Change: S112G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AbLIM_anchor
|
22 |
148 |
5.6e-54 |
PFAM |
|
low complexity region
|
171 |
183 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930407I10Rik |
A |
G |
15: 81,948,560 (GRCm39) |
D819G |
possibly damaging |
Het |
| Abca13 |
A |
T |
11: 9,243,167 (GRCm39) |
I1677L |
probably benign |
Het |
| Afdn |
G |
C |
17: 14,068,638 (GRCm39) |
|
probably null |
Het |
| Aldh6a1 |
A |
G |
12: 84,483,640 (GRCm39) |
L302P |
probably damaging |
Het |
| Ank3 |
A |
G |
10: 69,718,357 (GRCm39) |
D536G |
unknown |
Het |
| Ankrd17 |
A |
G |
5: 90,381,807 (GRCm39) |
V2454A |
possibly damaging |
Het |
| Apol7e |
G |
A |
15: 77,601,656 (GRCm39) |
E85K |
possibly damaging |
Het |
| Atmin |
A |
G |
8: 117,683,657 (GRCm39) |
D439G |
probably damaging |
Het |
| AU040320 |
G |
T |
4: 126,741,648 (GRCm39) |
C952F |
possibly damaging |
Het |
| Btbd8 |
G |
A |
5: 107,658,373 (GRCm39) |
E1648K |
probably benign |
Het |
| C6 |
A |
G |
15: 4,761,196 (GRCm39) |
S19G |
probably benign |
Het |
| Ccdc180 |
A |
T |
4: 45,930,009 (GRCm39) |
|
probably null |
Het |
| Cntn1 |
A |
C |
15: 92,212,423 (GRCm39) |
T862P |
probably benign |
Het |
| Col5a1 |
T |
C |
2: 27,859,812 (GRCm39) |
|
probably null |
Het |
| D430041D05Rik |
T |
C |
2: 104,031,650 (GRCm39) |
K964E |
probably damaging |
Het |
| Dnajc18 |
T |
C |
18: 35,819,846 (GRCm39) |
Y145C |
probably damaging |
Het |
| Dsc1 |
C |
T |
18: 20,240,737 (GRCm39) |
C196Y |
possibly damaging |
Het |
| Efcab11 |
A |
C |
12: 99,844,660 (GRCm39) |
I58R |
possibly damaging |
Het |
| Fam81b |
T |
A |
13: 76,419,398 (GRCm39) |
I51F |
probably benign |
Het |
| Fbln1 |
G |
A |
15: 85,111,262 (GRCm39) |
V139M |
probably damaging |
Het |
| Fbxw25 |
A |
G |
9: 109,493,598 (GRCm39) |
|
probably null |
Het |
| Fech |
C |
T |
18: 64,600,842 (GRCm39) |
W220* |
probably null |
Het |
| Fgl1 |
C |
T |
8: 41,644,624 (GRCm39) |
W293* |
probably null |
Het |
| Firrm |
A |
G |
1: 163,786,897 (GRCm39) |
I724T |
probably benign |
Het |
| Foxi2 |
T |
C |
7: 135,012,301 (GRCm39) |
L63P |
probably damaging |
Het |
| Frmpd1 |
A |
G |
4: 45,285,237 (GRCm39) |
R1353G |
possibly damaging |
Het |
| Fthl17b |
C |
T |
X: 8,829,043 (GRCm39) |
R9Q |
possibly damaging |
Het |
| Fthl17b |
C |
T |
X: 8,829,047 (GRCm39) |
V8M |
possibly damaging |
Het |
| Galnt5 |
T |
A |
2: 57,916,048 (GRCm39) |
|
probably null |
Het |
| Glb1 |
A |
T |
9: 114,303,017 (GRCm39) |
I618F |
probably damaging |
Het |
| Hs2st1 |
A |
T |
3: 144,141,357 (GRCm39) |
M237K |
probably benign |
Het |
| Ighm |
T |
C |
12: 113,386,293 (GRCm39) |
D19G |
|
Het |
| Il1f10 |
A |
G |
2: 24,182,829 (GRCm39) |
D35G |
probably benign |
Het |
| Itpr2 |
G |
A |
6: 146,292,436 (GRCm39) |
T419I |
probably damaging |
Het |
| Khdc1a |
A |
T |
1: 21,420,542 (GRCm39) |
E54V |
possibly damaging |
Het |
| Kif19a |
A |
G |
11: 114,681,065 (GRCm39) |
D991G |
probably benign |
Het |
| Klhl18 |
A |
C |
9: 110,257,843 (GRCm39) |
Y532* |
probably null |
Het |
| Lama1 |
T |
C |
17: 68,124,646 (GRCm39) |
F2902S |
|
Het |
| Lrba |
T |
C |
3: 86,571,835 (GRCm39) |
S2380P |
probably damaging |
Het |
| Lrp2 |
T |
A |
2: 69,367,925 (GRCm39) |
I196F |
probably damaging |
Het |
| Macf1 |
T |
C |
4: 123,369,524 (GRCm39) |
K1746E |
possibly damaging |
Het |
| Megf10 |
T |
C |
18: 57,424,866 (GRCm39) |
Y1002H |
probably benign |
Het |
| Megf8 |
A |
G |
7: 25,053,273 (GRCm39) |
T1815A |
probably benign |
Het |
| Mtg1 |
T |
C |
7: 139,724,610 (GRCm39) |
L162P |
probably damaging |
Het |
| Myo6 |
T |
A |
9: 80,195,328 (GRCm39) |
Y899* |
probably null |
Het |
| Nlrp9a |
A |
T |
7: 26,257,081 (GRCm39) |
D233V |
probably damaging |
Het |
| Or10al6 |
A |
T |
17: 38,082,571 (GRCm39) |
Q9L |
possibly damaging |
Het |
| Or2z2 |
T |
A |
11: 58,346,715 (GRCm39) |
N20I |
probably benign |
Het |
| Or4k45 |
C |
A |
2: 111,395,166 (GRCm39) |
V208L |
probably benign |
Het |
| Or6c201 |
T |
A |
10: 128,969,509 (GRCm39) |
I43F |
probably damaging |
Het |
| Or8k36-ps1 |
T |
A |
2: 86,437,063 (GRCm39) |
N284I |
unknown |
Het |
| Parvb |
A |
T |
15: 84,174,651 (GRCm39) |
Q148L |
probably damaging |
Het |
| Pcdhb11 |
C |
T |
18: 37,556,497 (GRCm39) |
T609M |
probably damaging |
Het |
| Pcdhga3 |
A |
T |
18: 37,809,178 (GRCm39) |
T544S |
probably benign |
Het |
| Pkd1 |
C |
G |
17: 24,788,715 (GRCm39) |
I824M |
probably benign |
Het |
| Pkd1l2 |
A |
T |
8: 117,794,849 (GRCm39) |
L370Q |
probably damaging |
Het |
| Plcb1 |
G |
T |
2: 135,093,684 (GRCm39) |
E166* |
probably null |
Het |
| Pnpt1 |
A |
G |
11: 29,085,522 (GRCm39) |
I138V |
probably benign |
Het |
| Pou4f3 |
T |
C |
18: 42,528,996 (GRCm39) |
L313P |
probably damaging |
Het |
| Pramel21 |
C |
A |
4: 143,342,744 (GRCm39) |
Q284K |
not run |
Het |
| Prep |
A |
G |
10: 44,996,910 (GRCm39) |
Y396C |
probably damaging |
Het |
| Prkd3 |
A |
T |
17: 79,269,974 (GRCm39) |
C562* |
probably null |
Het |
| Prss12 |
T |
A |
3: 123,276,425 (GRCm39) |
C351* |
probably null |
Het |
| Rnf41 |
C |
A |
10: 128,274,283 (GRCm39) |
H312N |
probably damaging |
Het |
| Ror1 |
C |
T |
4: 100,298,256 (GRCm39) |
T543I |
probably benign |
Het |
| Rreb1 |
G |
A |
13: 38,115,724 (GRCm39) |
V1028I |
probably benign |
Het |
| Setd2 |
T |
A |
9: 110,423,700 (GRCm39) |
S474T |
|
Het |
| Slc1a2 |
T |
A |
2: 102,570,275 (GRCm39) |
C184* |
probably null |
Het |
| Slc2a4 |
G |
A |
11: 69,837,202 (GRCm39) |
T78I |
probably benign |
Het |
| Slc4a4 |
T |
A |
5: 89,277,509 (GRCm39) |
I317N |
possibly damaging |
Het |
| Smad9 |
G |
A |
3: 54,693,747 (GRCm39) |
|
probably null |
Het |
| Sst |
T |
C |
16: 23,708,576 (GRCm39) |
E85G |
probably damaging |
Het |
| Sting1 |
T |
C |
18: 35,871,766 (GRCm39) |
Y162C |
probably damaging |
Het |
| Svep1 |
T |
G |
4: 58,066,468 (GRCm39) |
E3205D |
possibly damaging |
Het |
| Tmc7 |
G |
T |
7: 118,141,189 (GRCm39) |
S647R |
probably benign |
Het |
| Trnt1 |
T |
C |
6: 106,751,493 (GRCm39) |
S157P |
possibly damaging |
Het |
| Ttc6 |
A |
T |
12: 57,719,922 (GRCm39) |
H831L |
probably benign |
Het |
| Vmn1r121 |
A |
G |
7: 20,832,095 (GRCm39) |
F115S |
probably damaging |
Het |
| Vwa7 |
A |
G |
17: 35,238,020 (GRCm39) |
D207G |
possibly damaging |
Het |
| Vwde |
C |
A |
6: 13,204,980 (GRCm39) |
K300N |
probably null |
Het |
| Zfp418 |
A |
G |
7: 7,184,396 (GRCm39) |
T120A |
possibly damaging |
Het |
| Zfp687 |
C |
T |
3: 94,914,841 (GRCm39) |
R1220H |
probably damaging |
Het |
|
| Other mutations in Ablim2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00939:Ablim2
|
APN |
5 |
35,981,359 (GRCm39) |
unclassified |
probably benign |
|
|
IGL00945:Ablim2
|
APN |
5 |
35,994,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02439:Ablim2
|
APN |
5 |
36,015,206 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02664:Ablim2
|
APN |
5 |
36,006,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02897:Ablim2
|
APN |
5 |
35,990,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03034:Ablim2
|
APN |
5 |
35,985,509 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03096:Ablim2
|
APN |
5 |
36,040,743 (GRCm39) |
nonsense |
probably null |
|
|
IGL03384:Ablim2
|
APN |
5 |
36,032,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0128:Ablim2
|
UTSW |
5 |
35,966,520 (GRCm39) |
splice site |
probably benign |
|
|
R0130:Ablim2
|
UTSW |
5 |
35,966,520 (GRCm39) |
splice site |
probably benign |
|
|
R0212:Ablim2
|
UTSW |
5 |
36,006,254 (GRCm39) |
splice site |
probably null |
|
|
R0344:Ablim2
|
UTSW |
5 |
35,994,277 (GRCm39) |
splice site |
probably benign |
|
|
R0675:Ablim2
|
UTSW |
5 |
36,024,124 (GRCm39) |
splice site |
probably benign |
|
|
R0788:Ablim2
|
UTSW |
5 |
36,015,245 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1148:Ablim2
|
UTSW |
5 |
35,966,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Ablim2
|
UTSW |
5 |
35,966,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1493:Ablim2
|
UTSW |
5 |
35,966,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1809:Ablim2
|
UTSW |
5 |
36,000,614 (GRCm39) |
intron |
probably benign |
|
|
R2070:Ablim2
|
UTSW |
5 |
35,955,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2163:Ablim2
|
UTSW |
5 |
35,959,697 (GRCm39) |
splice site |
probably benign |
|
|
R3962:Ablim2
|
UTSW |
5 |
35,969,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4852:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4853:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4854:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4855:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4866:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4867:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4906:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4908:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4909:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4927:Ablim2
|
UTSW |
5 |
35,959,766 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5210:Ablim2
|
UTSW |
5 |
35,994,416 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5225:Ablim2
|
UTSW |
5 |
36,024,115 (GRCm39) |
splice site |
probably null |
|
|
R5439:Ablim2
|
UTSW |
5 |
36,015,170 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5528:Ablim2
|
UTSW |
5 |
36,013,510 (GRCm39) |
nonsense |
probably null |
|
|
R5629:Ablim2
|
UTSW |
5 |
36,014,507 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5653:Ablim2
|
UTSW |
5 |
36,040,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Ablim2
|
UTSW |
5 |
35,969,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6059:Ablim2
|
UTSW |
5 |
36,014,508 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6241:Ablim2
|
UTSW |
5 |
36,032,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7562:Ablim2
|
UTSW |
5 |
36,030,563 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7960:Ablim2
|
UTSW |
5 |
36,014,493 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8414:Ablim2
|
UTSW |
5 |
36,032,235 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8557:Ablim2
|
UTSW |
5 |
35,985,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8690:Ablim2
|
UTSW |
5 |
36,030,518 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8710:Ablim2
|
UTSW |
5 |
36,030,518 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8713:Ablim2
|
UTSW |
5 |
36,030,518 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R9059:Ablim2
|
UTSW |
5 |
35,959,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9452:Ablim2
|
UTSW |
5 |
36,015,198 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9622:Ablim2
|
UTSW |
5 |
36,006,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ablim2
|
UTSW |
5 |
36,006,202 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
Z1177:Ablim2
|
UTSW |
5 |
35,998,637 (GRCm39) |
small deletion |
probably benign |
|
|
Z1177:Ablim2
|
UTSW |
5 |
35,981,387 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1188:Ablim2
|
UTSW |
5 |
35,994,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTTGAAGAGCCTGTTAGGG -3'
(R):5'- TATGTCTAAGTGGCCAGACATTCC -3'
Sequencing Primer
(F):5'- GTTATGTTGTTTCTGCCCCTGAGATC -3'
(R):5'- TGGCCAGACATTCCATGGC -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation