Incidental Mutation 'R7502:St18'
| ID |
581508 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
St18
|
| Ensembl Gene |
ENSMUSG00000033740 |
| Gene Name |
suppression of tumorigenicity 18 |
| Synonyms |
Nzf3, Myt3 |
| MMRRC Submission |
045575-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7502 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
6557455-6931164 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 6898194 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 665
(N665K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042056
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043578]
[ENSMUST00000131494]
[ENSMUST00000140079]
[ENSMUST00000150761]
[ENSMUST00000151281]
[ENSMUST00000163727]
|
| AlphaFold |
Q80TY4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043578
AA Change: N665K
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000042056
Gene: ENSMUSG00000033740
AA Change: N665K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131494
AA Change: N665K
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000117789
Gene: ENSMUSG00000033740
AA Change: N665K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140079
AA Change: N665K
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000118322
Gene: ENSMUSG00000033740
AA Change: N665K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150761
AA Change: N665K
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000120298
Gene: ENSMUSG00000033740
AA Change: N665K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151281
AA Change: N665K
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000122055
Gene: ENSMUSG00000033740
AA Change: N665K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163727
AA Change: N665K
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000131417
Gene: ENSMUSG00000033740
AA Change: N665K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acan |
A |
G |
7: 78,743,951 (GRCm39) |
T661A |
probably damaging |
Het |
| Actrt2 |
T |
C |
4: 154,751,383 (GRCm39) |
Y251C |
probably benign |
Het |
| Adat3 |
T |
A |
10: 80,442,255 (GRCm39) |
V31D |
probably damaging |
Het |
| Adgrf4 |
T |
C |
17: 42,980,548 (GRCm39) |
H179R |
possibly damaging |
Het |
| Ahcyl1 |
A |
T |
3: 107,578,513 (GRCm39) |
Y241* |
probably null |
Het |
| Anks1 |
C |
A |
17: 28,227,114 (GRCm39) |
T589K |
possibly damaging |
Het |
| Arhgap15 |
A |
G |
2: 43,670,630 (GRCm39) |
T5A |
probably benign |
Het |
| Cacna1e |
A |
T |
1: 154,344,734 (GRCm39) |
M1130K |
probably null |
Het |
| Ccdc121rt1 |
G |
A |
1: 181,338,443 (GRCm39) |
Q170* |
probably null |
Het |
| Ceacam18 |
A |
T |
7: 43,286,298 (GRCm39) |
D57V |
probably damaging |
Het |
| Celf1 |
C |
T |
2: 90,835,100 (GRCm39) |
Q194* |
probably null |
Het |
| Celsr2 |
T |
A |
3: 108,306,218 (GRCm39) |
T2029S |
probably benign |
Het |
| Cep170 |
T |
C |
1: 176,583,595 (GRCm39) |
D163G |
probably damaging |
Het |
| Cfap210 |
A |
T |
2: 69,606,488 (GRCm39) |
D309E |
probably benign |
Het |
| Cftr |
T |
C |
6: 18,214,295 (GRCm39) |
F157S |
probably damaging |
Het |
| Chchd3 |
T |
C |
6: 32,945,164 (GRCm39) |
E114G |
probably damaging |
Het |
| Cntnap2 |
T |
A |
6: 46,460,963 (GRCm39) |
S666R |
possibly damaging |
Het |
| Col6a5 |
C |
T |
9: 105,753,075 (GRCm39) |
V2266I |
probably benign |
Het |
| Ctr9 |
A |
G |
7: 110,633,133 (GRCm39) |
D127G |
probably benign |
Het |
| Ctsl |
A |
T |
13: 64,514,882 (GRCm39) |
F141I |
probably damaging |
Het |
| Dcpp1 |
T |
A |
17: 24,101,615 (GRCm39) |
Y121* |
probably null |
Het |
| Ddx42 |
T |
C |
11: 106,138,565 (GRCm39) |
V788A |
probably benign |
Het |
| Ehd4 |
T |
C |
2: 119,921,874 (GRCm39) |
I461V |
probably benign |
Het |
| Elp6 |
C |
A |
9: 110,134,376 (GRCm39) |
L5I |
possibly damaging |
Het |
| Faap20 |
T |
C |
4: 155,334,793 (GRCm39) |
S2P |
|
Het |
| Fam98b |
A |
C |
2: 117,094,344 (GRCm39) |
Y218S |
probably damaging |
Het |
| Fbxl4 |
T |
A |
4: 22,376,655 (GRCm39) |
D30E |
probably benign |
Het |
| Fcrlb |
T |
C |
1: 170,736,210 (GRCm39) |
T189A |
probably damaging |
Het |
| Gfpt1 |
A |
G |
6: 87,043,671 (GRCm39) |
D302G |
probably benign |
Het |
| Gzmg |
T |
G |
14: 56,394,284 (GRCm39) |
E203D |
not run |
Het |
| Hsph1 |
A |
C |
5: 149,553,838 (GRCm39) |
V210G |
probably damaging |
Het |
| Il20rb |
A |
T |
9: 100,350,479 (GRCm39) |
M138K |
probably damaging |
Het |
| Itpr1 |
A |
T |
6: 108,360,639 (GRCm39) |
E688D |
probably benign |
Het |
| Jmjd1c |
T |
G |
10: 67,067,794 (GRCm39) |
S1585A |
probably damaging |
Het |
| Kcnk3 |
A |
T |
5: 30,780,062 (GRCm39) |
T371S |
possibly damaging |
Het |
| Kif11 |
T |
A |
19: 37,398,255 (GRCm39) |
S694T |
possibly damaging |
Het |
| Kpna7 |
T |
A |
5: 144,942,731 (GRCm39) |
H85L |
probably benign |
Het |
| Lipf |
A |
T |
19: 33,954,006 (GRCm39) |
I366F |
probably damaging |
Het |
| Lrrc27 |
A |
G |
7: 138,794,748 (GRCm39) |
H37R |
probably benign |
Het |
| Mki67 |
T |
C |
7: 135,302,512 (GRCm39) |
T841A |
possibly damaging |
Het |
| Mtss1 |
A |
G |
15: 58,820,210 (GRCm39) |
S120P |
probably damaging |
Het |
| Nav1 |
A |
G |
1: 135,397,404 (GRCm39) |
W922R |
probably damaging |
Het |
| Nwd1 |
A |
G |
8: 73,434,021 (GRCm39) |
E1206G |
probably damaging |
Het |
| Obscn |
T |
C |
11: 58,885,635 (GRCm39) |
S7933G |
unknown |
Het |
| Or13j1 |
T |
C |
4: 43,706,316 (GRCm39) |
H84R |
probably damaging |
Het |
| Or1p4-ps1 |
T |
C |
11: 74,208,010 (GRCm39) |
V53A |
probably benign |
Het |
| Or2g25 |
T |
A |
17: 37,971,122 (GRCm39) |
Y34F |
probably damaging |
Het |
| Or2k2 |
T |
C |
4: 58,785,648 (GRCm39) |
I25V |
probably benign |
Het |
| Or4c52 |
T |
C |
2: 89,845,355 (GRCm39) |
L27S |
probably benign |
Het |
| Otog |
A |
T |
7: 45,948,039 (GRCm39) |
I162F |
probably damaging |
Het |
| Paf1 |
G |
A |
7: 28,095,293 (GRCm39) |
V153I |
possibly damaging |
Het |
| Pcdhga11 |
T |
A |
18: 37,889,554 (GRCm39) |
D187E |
probably benign |
Het |
| Peg10 |
CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG |
CCACATCAGGATCCACATCAGGATGCACATCAG |
6: 4,756,398 (GRCm39) |
|
probably benign |
Het |
| Pitrm1 |
G |
T |
13: 6,610,658 (GRCm39) |
R424L |
probably damaging |
Het |
| Pla2g4e |
T |
A |
2: 120,004,819 (GRCm39) |
|
probably null |
Het |
| Plaat1 |
T |
C |
16: 29,046,919 (GRCm39) |
V146A |
probably benign |
Het |
| Prorp |
T |
C |
12: 55,351,206 (GRCm39) |
Y172H |
probably damaging |
Het |
| Prrc2a |
T |
C |
17: 35,381,286 (GRCm39) |
N61S |
unknown |
Het |
| Ror1 |
T |
A |
4: 100,190,827 (GRCm39) |
D61E |
probably benign |
Het |
| Ryr3 |
G |
A |
2: 112,542,706 (GRCm39) |
P3168S |
probably benign |
Het |
| Serinc4 |
T |
A |
2: 121,284,250 (GRCm39) |
I289F |
probably damaging |
Het |
| Sez6l |
A |
T |
5: 112,623,347 (GRCm39) |
L68H |
possibly damaging |
Het |
| Sez6l2 |
A |
G |
7: 126,560,915 (GRCm39) |
E460G |
probably benign |
Het |
| Sh3tc1 |
C |
T |
5: 35,863,406 (GRCm39) |
G927D |
probably damaging |
Het |
| Slc22a27 |
G |
C |
19: 7,903,747 (GRCm39) |
T130S |
probably damaging |
Het |
| Slc38a8 |
C |
A |
8: 120,227,820 (GRCm39) |
A37S |
possibly damaging |
Het |
| Slc40a1 |
T |
C |
1: 45,958,134 (GRCm39) |
N100D |
probably damaging |
Het |
| Slc49a3 |
G |
A |
5: 108,591,646 (GRCm39) |
|
probably null |
Het |
| Snx30 |
T |
C |
4: 59,894,567 (GRCm39) |
F382L |
possibly damaging |
Het |
| Sox1 |
A |
G |
8: 12,446,913 (GRCm39) |
N185D |
possibly damaging |
Het |
| Spsb1 |
C |
T |
4: 149,991,385 (GRCm39) |
R61H |
possibly damaging |
Het |
| Sptbn2 |
T |
C |
19: 4,798,110 (GRCm39) |
V1945A |
probably benign |
Het |
| Syne1 |
A |
G |
10: 5,283,446 (GRCm39) |
S1540P |
probably damaging |
Het |
| Syne2 |
G |
A |
12: 76,141,100 (GRCm39) |
V1331M |
probably damaging |
Het |
| Tfap2c |
T |
C |
2: 172,393,639 (GRCm39) |
S185P |
probably benign |
Het |
| Tnfsf8 |
T |
A |
4: 63,769,398 (GRCm39) |
D71V |
probably damaging |
Het |
| Tnn |
T |
C |
1: 159,937,929 (GRCm39) |
D1196G |
probably benign |
Het |
| Ttll8 |
A |
G |
15: 88,817,639 (GRCm39) |
|
probably null |
Het |
| Tubgcp3 |
A |
G |
8: 12,691,207 (GRCm39) |
F444L |
probably damaging |
Het |
| Txndc11 |
G |
A |
16: 10,905,742 (GRCm39) |
P596L |
probably benign |
Het |
| Ubr4 |
C |
T |
4: 139,139,983 (GRCm39) |
P1189S |
possibly damaging |
Het |
| Usp32 |
T |
C |
11: 84,913,724 (GRCm39) |
D869G |
possibly damaging |
Het |
| Vmn1r202 |
G |
T |
13: 22,686,188 (GRCm39) |
N76K |
probably damaging |
Het |
| Wfdc6a |
C |
T |
2: 164,421,761 (GRCm39) |
M132I |
probably benign |
Het |
| Wnk2 |
A |
T |
13: 49,300,720 (GRCm39) |
|
probably null |
Het |
| Xbp1 |
A |
G |
11: 5,474,683 (GRCm39) |
|
probably null |
Het |
| Zfp551 |
A |
T |
7: 12,149,725 (GRCm39) |
Y561* |
probably null |
Het |
|
| Other mutations in St18 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:St18
|
APN |
1 |
6,872,796 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00840:St18
|
APN |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01016:St18
|
APN |
1 |
6,914,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01116:St18
|
APN |
1 |
6,872,856 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01719:St18
|
APN |
1 |
6,916,020 (GRCm39) |
splice site |
probably benign |
|
|
IGL01885:St18
|
APN |
1 |
6,914,596 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02486:St18
|
APN |
1 |
6,890,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02611:St18
|
APN |
1 |
6,839,114 (GRCm39) |
splice site |
probably benign |
|
|
IGL02742:St18
|
APN |
1 |
6,872,540 (GRCm39) |
splice site |
probably benign |
|
|
IGL02953:St18
|
APN |
1 |
6,914,337 (GRCm39) |
splice site |
probably benign |
|
|
IGL02999:St18
|
APN |
1 |
6,887,829 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03092:St18
|
APN |
1 |
6,839,118 (GRCm39) |
splice site |
probably benign |
|
|
Smallish
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03055:St18
|
UTSW |
1 |
6,872,959 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0089:St18
|
UTSW |
1 |
6,919,172 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0257:St18
|
UTSW |
1 |
6,890,186 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0383:St18
|
UTSW |
1 |
6,873,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0588:St18
|
UTSW |
1 |
6,887,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0989:St18
|
UTSW |
1 |
6,898,105 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1068:St18
|
UTSW |
1 |
6,865,786 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1311:St18
|
UTSW |
1 |
6,915,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:St18
|
UTSW |
1 |
6,915,793 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1723:St18
|
UTSW |
1 |
6,880,909 (GRCm39) |
splice site |
probably benign |
|
|
R1926:St18
|
UTSW |
1 |
6,872,913 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1927:St18
|
UTSW |
1 |
6,872,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2035:St18
|
UTSW |
1 |
6,872,552 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:St18
|
UTSW |
1 |
6,898,195 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2139:St18
|
UTSW |
1 |
6,880,839 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2261:St18
|
UTSW |
1 |
6,915,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2300:St18
|
UTSW |
1 |
6,925,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2322:St18
|
UTSW |
1 |
6,914,348 (GRCm39) |
nonsense |
probably null |
|
|
R2846:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3738:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3739:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3772:St18
|
UTSW |
1 |
6,914,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3805:St18
|
UTSW |
1 |
6,872,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3953:St18
|
UTSW |
1 |
6,873,117 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4034:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4036:St18
|
UTSW |
1 |
6,898,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4407:St18
|
UTSW |
1 |
6,898,061 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4527:St18
|
UTSW |
1 |
6,925,647 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4740:St18
|
UTSW |
1 |
6,887,828 (GRCm39) |
missense |
probably benign |
|
|
R4838:St18
|
UTSW |
1 |
6,873,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5182:St18
|
UTSW |
1 |
6,887,877 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5186:St18
|
UTSW |
1 |
6,872,541 (GRCm39) |
splice site |
probably null |
|
|
R5354:St18
|
UTSW |
1 |
6,914,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5423:St18
|
UTSW |
1 |
6,872,840 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5724:St18
|
UTSW |
1 |
6,841,174 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6182:St18
|
UTSW |
1 |
6,914,342 (GRCm39) |
splice site |
probably null |
|
|
R6491:St18
|
UTSW |
1 |
6,898,209 (GRCm39) |
nonsense |
probably null |
|
|
R6503:St18
|
UTSW |
1 |
6,865,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7037:St18
|
UTSW |
1 |
6,873,260 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7098:St18
|
UTSW |
1 |
6,898,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7132:St18
|
UTSW |
1 |
6,929,351 (GRCm39) |
missense |
|
|
|
R7144:St18
|
UTSW |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7150:St18
|
UTSW |
1 |
6,873,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7334:St18
|
UTSW |
1 |
6,872,783 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7729:St18
|
UTSW |
1 |
6,872,761 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7848:St18
|
UTSW |
1 |
6,927,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8088:St18
|
UTSW |
1 |
6,898,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8299:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8338:St18
|
UTSW |
1 |
6,879,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8690:St18
|
UTSW |
1 |
6,872,788 (GRCm39) |
missense |
probably benign |
|
|
R8753:St18
|
UTSW |
1 |
6,916,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8808:St18
|
UTSW |
1 |
6,880,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8880:St18
|
UTSW |
1 |
6,865,619 (GRCm39) |
nonsense |
probably null |
|
|
R9055:St18
|
UTSW |
1 |
6,873,206 (GRCm39) |
nonsense |
probably null |
|
|
R9292:St18
|
UTSW |
1 |
6,898,106 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9322:St18
|
UTSW |
1 |
6,865,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9530:St18
|
UTSW |
1 |
6,872,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9603:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9611:St18
|
UTSW |
1 |
6,873,147 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9639:St18
|
UTSW |
1 |
6,929,246 (GRCm39) |
missense |
|
|
|
R9644:St18
|
UTSW |
1 |
6,929,276 (GRCm39) |
missense |
|
|
|
R9740:St18
|
UTSW |
1 |
6,873,287 (GRCm39) |
nonsense |
probably null |
|
|
R9750:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCACATTGGACTTAAGCATG -3'
(R):5'- TGTGAGGACAACTTCTACCATC -3'
Sequencing Primer
(F):5'- CGAATCCACGACAAGTCTAT -3'
(R):5'- ATACAGTGGCTCATGGTCATC -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation