Incidental Mutation 'R0616:Arap1'
| ID |
58324 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap1
|
| Ensembl Gene |
ENSMUSG00000032812 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| Synonyms |
Centd2, 2410002L19Rik |
| MMRRC Submission |
038805-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0616 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
100997296-101061793 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 101050857 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glycine
at position 1152
(R1152G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102624
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000084895]
[ENSMUST00000084896]
[ENSMUST00000098243]
[ENSMUST00000107010]
|
| AlphaFold |
Q4LDD4 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000084895
AA Change: R904G
PolyPhen 2
Score 0.619 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000081957
Gene: ENSMUSG00000032812
AA Change: R904G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
37 |
N/A |
INTRINSIC |
|
PH
|
82 |
175 |
2.62e-17 |
SMART |
|
PH
|
195 |
285 |
3.6e-6 |
SMART |
|
ArfGap
|
289 |
415 |
2.4e-22 |
SMART |
|
PH
|
498 |
606 |
1.23e-13 |
SMART |
|
PH
|
616 |
710 |
1.08e0 |
SMART |
|
RhoGAP
|
722 |
904 |
1.35e-63 |
SMART |
|
Pfam:RA
|
926 |
1015 |
1.5e-10 |
PFAM |
|
PH
|
1029 |
1141 |
8.58e-13 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000084896
AA Change: R1152G
PolyPhen 2
Score 0.638 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000081958
Gene: ENSMUSG00000032812
AA Change: R1152G
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
1.72e-7 |
SMART |
|
low complexity region
|
92 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
135 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
167 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
227 |
N/A |
INTRINSIC |
|
low complexity region
|
267 |
285 |
N/A |
INTRINSIC |
|
PH
|
330 |
423 |
2.62e-17 |
SMART |
|
PH
|
443 |
533 |
3.6e-6 |
SMART |
|
ArfGap
|
537 |
663 |
2.4e-22 |
SMART |
|
PH
|
746 |
854 |
1.23e-13 |
SMART |
|
PH
|
864 |
958 |
1.08e0 |
SMART |
|
RhoGAP
|
970 |
1152 |
1.35e-63 |
SMART |
|
Pfam:RA
|
1174 |
1263 |
6.6e-13 |
PFAM |
|
PH
|
1277 |
1400 |
8e-13 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098243
AA Change: R438G
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000095844
Gene: ENSMUSG00000032812
AA Change: R438G
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
32 |
140 |
1.23e-13 |
SMART |
|
PH
|
150 |
244 |
1.08e0 |
SMART |
|
RhoGAP
|
256 |
438 |
1.35e-63 |
SMART |
|
Pfam:RA
|
460 |
549 |
1.2e-11 |
PFAM |
|
PH
|
563 |
675 |
8.58e-13 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000107010
AA Change: R1152G
PolyPhen 2
Score 0.638 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000102624
Gene: ENSMUSG00000032812
AA Change: R1152G
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
1.72e-7 |
SMART |
|
low complexity region
|
92 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
115 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
135 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
167 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
227 |
N/A |
INTRINSIC |
|
low complexity region
|
267 |
285 |
N/A |
INTRINSIC |
|
PH
|
330 |
423 |
2.62e-17 |
SMART |
|
PH
|
443 |
533 |
3.6e-6 |
SMART |
|
ArfGap
|
537 |
663 |
2.4e-22 |
SMART |
|
PH
|
746 |
854 |
1.23e-13 |
SMART |
|
PH
|
864 |
958 |
1.08e0 |
SMART |
|
RhoGAP
|
970 |
1152 |
1.35e-63 |
SMART |
|
Pfam:RA
|
1174 |
1263 |
1.9e-10 |
PFAM |
|
PH
|
1277 |
1389 |
8.58e-13 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125284
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153340
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156017
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000210162
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.5%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca12 |
G |
T |
1: 71,341,830 (GRCm39) |
Q1044K |
probably damaging |
Het |
| Abi3bp |
A |
T |
16: 56,474,433 (GRCm39) |
T723S |
probably damaging |
Het |
| Ackr3 |
G |
A |
1: 90,142,191 (GRCm39) |
V217I |
probably benign |
Het |
| Acnat2 |
A |
G |
4: 49,380,269 (GRCm39) |
S370P |
probably damaging |
Het |
| Arhgap15 |
G |
A |
2: 44,006,729 (GRCm39) |
|
probably null |
Het |
| Arhgap5 |
C |
T |
12: 52,563,848 (GRCm39) |
T273I |
possibly damaging |
Het |
| Armh4 |
G |
T |
14: 50,011,113 (GRCm39) |
T198K |
possibly damaging |
Het |
| C1s2 |
T |
C |
6: 124,605,723 (GRCm39) |
E332G |
probably damaging |
Het |
| Camp |
G |
A |
9: 109,677,707 (GRCm39) |
R88W |
probably benign |
Het |
| Cdkl2 |
A |
G |
5: 92,156,863 (GRCm39) |
M564T |
probably benign |
Het |
| Ceacam20 |
A |
G |
7: 19,704,321 (GRCm39) |
H124R |
probably benign |
Het |
| Cep19 |
C |
T |
16: 31,922,829 (GRCm39) |
R32C |
probably damaging |
Het |
| Cep295 |
G |
A |
9: 15,243,618 (GRCm39) |
Q1565* |
probably null |
Het |
| Chd3 |
T |
C |
11: 69,236,313 (GRCm39) |
E1932G |
probably damaging |
Het |
| Cibar1 |
G |
A |
4: 12,168,234 (GRCm39) |
R210* |
probably null |
Het |
| Cnr2 |
G |
T |
4: 135,644,873 (GRCm39) |
W317L |
probably benign |
Het |
| Cntnap5a |
C |
T |
1: 116,508,279 (GRCm39) |
H1264Y |
possibly damaging |
Het |
| Depdc7 |
T |
A |
2: 104,557,650 (GRCm39) |
N200I |
probably benign |
Het |
| Dock4 |
T |
C |
12: 40,754,414 (GRCm39) |
S468P |
probably benign |
Het |
| Dscc1 |
C |
A |
15: 54,946,966 (GRCm39) |
C253F |
probably benign |
Het |
| Fam217a |
C |
A |
13: 35,097,666 (GRCm39) |
S55I |
probably benign |
Het |
| Farp1 |
G |
A |
14: 121,514,434 (GRCm39) |
R921H |
probably damaging |
Het |
| Fat4 |
A |
G |
3: 38,997,019 (GRCm39) |
D1746G |
probably damaging |
Het |
| Fbxw5 |
T |
C |
2: 25,392,517 (GRCm39) |
F100L |
probably damaging |
Het |
| Gli3 |
C |
A |
13: 15,836,991 (GRCm39) |
T458K |
possibly damaging |
Het |
| Gm4841 |
T |
C |
18: 60,404,009 (GRCm39) |
Y28C |
probably benign |
Het |
| Gprc5d |
T |
C |
6: 135,093,430 (GRCm39) |
E159G |
probably benign |
Het |
| Grm4 |
A |
T |
17: 27,653,538 (GRCm39) |
I757N |
probably damaging |
Het |
| Hagh |
A |
G |
17: 25,076,551 (GRCm39) |
Y94C |
probably damaging |
Het |
| Hycc1 |
T |
C |
5: 24,191,770 (GRCm39) |
T44A |
probably damaging |
Het |
| Itpkb |
T |
C |
1: 180,249,301 (GRCm39) |
I892T |
probably damaging |
Het |
| Kcmf1 |
T |
C |
6: 72,827,467 (GRCm39) |
I58V |
probably benign |
Het |
| Khdrbs2 |
A |
G |
1: 32,506,856 (GRCm39) |
I167V |
possibly damaging |
Het |
| Kmt2c |
A |
G |
5: 25,504,250 (GRCm39) |
I275T |
probably benign |
Het |
| Lingo4 |
A |
G |
3: 94,310,388 (GRCm39) |
K442R |
probably benign |
Het |
| Mak |
T |
C |
13: 41,195,661 (GRCm39) |
N382D |
probably benign |
Het |
| Maob |
G |
A |
X: 16,576,402 (GRCm39) |
T480I |
possibly damaging |
Het |
| Mcoln1 |
A |
G |
8: 3,565,025 (GRCm39) |
E573G |
probably benign |
Het |
| Ms4a6b |
G |
A |
19: 11,504,262 (GRCm39) |
|
probably null |
Het |
| Muc5ac |
A |
G |
7: 141,349,981 (GRCm39) |
M576V |
probably benign |
Het |
| Nme8 |
T |
A |
13: 19,875,029 (GRCm39) |
D126V |
probably benign |
Het |
| Npy2r |
T |
A |
3: 82,448,670 (GRCm39) |
D35V |
possibly damaging |
Het |
| Nrxn1 |
T |
C |
17: 90,670,285 (GRCm39) |
D193G |
probably damaging |
Het |
| Or2g7 |
A |
C |
17: 38,378,131 (GRCm39) |
E23A |
probably damaging |
Het |
| Or2y1e |
T |
C |
11: 49,218,583 (GRCm39) |
L115P |
probably damaging |
Het |
| Or4c10b |
T |
A |
2: 89,711,935 (GRCm39) |
V255E |
probably benign |
Het |
| Or4d5 |
A |
T |
9: 40,012,283 (GRCm39) |
F168I |
probably damaging |
Het |
| Or52b4i |
T |
A |
7: 102,191,761 (GRCm39) |
M206K |
possibly damaging |
Het |
| Or6d14 |
A |
G |
6: 116,533,889 (GRCm39) |
I168V |
probably benign |
Het |
| Or8b3b |
A |
T |
9: 38,584,776 (GRCm39) |
M1K |
probably null |
Het |
| Or8c17 |
G |
T |
9: 38,180,630 (GRCm39) |
V266L |
probably benign |
Het |
| Or8g18 |
G |
A |
9: 39,148,946 (GRCm39) |
T258M |
probably benign |
Het |
| Pabpc2 |
A |
T |
18: 39,906,792 (GRCm39) |
H19L |
possibly damaging |
Het |
| Pcdhb9 |
A |
T |
18: 37,535,028 (GRCm39) |
K341* |
probably null |
Het |
| Pde4dip |
T |
C |
3: 97,654,849 (GRCm39) |
I859M |
probably benign |
Het |
| Pfkfb2 |
T |
C |
1: 130,634,159 (GRCm39) |
|
probably null |
Het |
| Pigg |
C |
T |
5: 108,461,951 (GRCm39) |
T94M |
probably damaging |
Het |
| Pik3c2b |
T |
C |
1: 133,028,569 (GRCm39) |
F1353L |
probably damaging |
Het |
| Prg4 |
T |
C |
1: 150,336,462 (GRCm39) |
D87G |
probably damaging |
Het |
| Prkdc |
A |
T |
16: 15,508,271 (GRCm39) |
D974V |
probably damaging |
Het |
| Prmt3 |
A |
G |
7: 49,437,076 (GRCm39) |
Y217C |
probably damaging |
Het |
| Proser1 |
A |
G |
3: 53,382,118 (GRCm39) |
T192A |
probably damaging |
Het |
| Rab3d |
G |
A |
9: 21,826,060 (GRCm39) |
T118M |
probably damaging |
Het |
| Rb1cc1 |
A |
G |
1: 6,314,486 (GRCm39) |
K386R |
possibly damaging |
Het |
| Rcn2 |
A |
G |
9: 55,963,534 (GRCm39) |
D221G |
probably benign |
Het |
| Rhbdl3 |
T |
G |
11: 80,222,687 (GRCm39) |
H245Q |
probably damaging |
Het |
| Ribc1 |
T |
C |
X: 150,788,787 (GRCm39) |
E204G |
probably damaging |
Het |
| Rpap1 |
G |
A |
2: 119,608,601 (GRCm39) |
L254F |
probably damaging |
Het |
| Rrp12 |
A |
G |
19: 41,880,988 (GRCm39) |
F148L |
possibly damaging |
Het |
| Rusf1 |
A |
T |
7: 127,871,803 (GRCm39) |
|
probably null |
Het |
| Setdb1 |
A |
T |
3: 95,249,109 (GRCm39) |
I333K |
probably damaging |
Het |
| Simc1 |
A |
G |
13: 54,694,845 (GRCm39) |
I1210V |
probably benign |
Het |
| Smchd1 |
T |
A |
17: 71,686,569 (GRCm39) |
D1379V |
probably benign |
Het |
| Snap29 |
A |
T |
16: 17,240,370 (GRCm39) |
K159* |
probably null |
Het |
| Spdye4c |
A |
T |
2: 128,436,132 (GRCm39) |
K176M |
possibly damaging |
Het |
| Stk31 |
T |
A |
6: 49,400,419 (GRCm39) |
W415R |
probably damaging |
Het |
| Supt6 |
C |
T |
11: 78,100,321 (GRCm39) |
R1497Q |
probably damaging |
Het |
| Tenm3 |
A |
G |
8: 48,729,191 (GRCm39) |
I1605T |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,676,967 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
G |
2: 76,728,011 (GRCm39) |
|
probably benign |
Het |
| Ucp3 |
A |
T |
7: 100,129,368 (GRCm39) |
T68S |
probably benign |
Het |
| Ugt2b36 |
T |
C |
5: 87,237,336 (GRCm39) |
N316D |
probably benign |
Het |
| Usp4 |
T |
G |
9: 108,244,003 (GRCm39) |
S247A |
probably benign |
Het |
| Utp20 |
A |
T |
10: 88,606,613 (GRCm39) |
V1653D |
probably benign |
Het |
| Vmn1r183 |
A |
G |
7: 23,754,250 (GRCm39) |
I18V |
probably benign |
Het |
| Vmn1r237 |
A |
G |
17: 21,534,885 (GRCm39) |
M203V |
probably damaging |
Het |
| Vmn1r61 |
A |
T |
7: 5,613,998 (GRCm39) |
F105L |
possibly damaging |
Het |
| Zfp462 |
T |
C |
4: 55,011,951 (GRCm39) |
C158R |
probably damaging |
Het |
| Zfyve16 |
C |
G |
13: 92,657,637 (GRCm39) |
R758P |
probably damaging |
Het |
|
| Other mutations in Arap1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00517:Arap1
|
APN |
7 |
101,037,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01311:Arap1
|
APN |
7 |
101,037,343 (GRCm39) |
nonsense |
probably null |
|
|
IGL01349:Arap1
|
APN |
7 |
101,036,359 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL01521:Arap1
|
APN |
7 |
101,049,812 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01869:Arap1
|
APN |
7 |
101,049,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02156:Arap1
|
APN |
7 |
101,037,937 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02320:Arap1
|
APN |
7 |
101,034,236 (GRCm39) |
missense |
probably benign |
|
|
IGL02478:Arap1
|
APN |
7 |
101,049,332 (GRCm39) |
splice site |
probably null |
|
|
R0133:Arap1
|
UTSW |
7 |
101,035,436 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0233:Arap1
|
UTSW |
7 |
101,049,448 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0233:Arap1
|
UTSW |
7 |
101,049,448 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0412:Arap1
|
UTSW |
7 |
101,039,429 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0838:Arap1
|
UTSW |
7 |
101,049,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0962:Arap1
|
UTSW |
7 |
101,034,121 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1186:Arap1
|
UTSW |
7 |
101,053,476 (GRCm39) |
splice site |
probably benign |
|
|
R1405:Arap1
|
UTSW |
7 |
101,047,643 (GRCm39) |
splice site |
probably null |
|
|
R1405:Arap1
|
UTSW |
7 |
101,047,643 (GRCm39) |
splice site |
probably null |
|
|
R1724:Arap1
|
UTSW |
7 |
101,049,733 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1793:Arap1
|
UTSW |
7 |
101,037,829 (GRCm39) |
missense |
probably benign |
|
|
R1959:Arap1
|
UTSW |
7 |
101,022,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Arap1
|
UTSW |
7 |
101,022,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Arap1
|
UTSW |
7 |
101,050,725 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2128:Arap1
|
UTSW |
7 |
101,058,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3737:Arap1
|
UTSW |
7 |
101,049,484 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3851:Arap1
|
UTSW |
7 |
101,039,372 (GRCm39) |
nonsense |
probably null |
|
|
R4034:Arap1
|
UTSW |
7 |
101,049,484 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4386:Arap1
|
UTSW |
7 |
101,034,778 (GRCm39) |
missense |
probably benign |
|
|
R4435:Arap1
|
UTSW |
7 |
101,039,461 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4779:Arap1
|
UTSW |
7 |
101,053,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4786:Arap1
|
UTSW |
7 |
101,034,212 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4850:Arap1
|
UTSW |
7 |
101,047,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Arap1
|
UTSW |
7 |
101,051,009 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5253:Arap1
|
UTSW |
7 |
101,037,851 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5342:Arap1
|
UTSW |
7 |
101,054,167 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5367:Arap1
|
UTSW |
7 |
101,058,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5397:Arap1
|
UTSW |
7 |
101,034,119 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5968:Arap1
|
UTSW |
7 |
101,043,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6052:Arap1
|
UTSW |
7 |
101,053,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6574:Arap1
|
UTSW |
7 |
101,053,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6645:Arap1
|
UTSW |
7 |
101,057,318 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R7060:Arap1
|
UTSW |
7 |
101,058,564 (GRCm39) |
splice site |
probably null |
|
|
R7191:Arap1
|
UTSW |
7 |
101,034,199 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7323:Arap1
|
UTSW |
7 |
101,049,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7349:Arap1
|
UTSW |
7 |
101,039,435 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7516:Arap1
|
UTSW |
7 |
101,058,538 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7922:Arap1
|
UTSW |
7 |
101,053,621 (GRCm39) |
nonsense |
probably null |
|
|
R8034:Arap1
|
UTSW |
7 |
101,043,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8293:Arap1
|
UTSW |
7 |
101,050,141 (GRCm39) |
missense |
probably benign |
|
|
R8493:Arap1
|
UTSW |
7 |
101,035,725 (GRCm39) |
nonsense |
probably null |
|
|
R8810:Arap1
|
UTSW |
7 |
101,053,585 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8811:Arap1
|
UTSW |
7 |
101,036,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8928:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8930:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8931:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8941:Arap1
|
UTSW |
7 |
101,057,324 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9014:Arap1
|
UTSW |
7 |
101,053,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9144:Arap1
|
UTSW |
7 |
101,047,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9164:Arap1
|
UTSW |
7 |
101,041,090 (GRCm39) |
nonsense |
probably null |
|
|
R9215:Arap1
|
UTSW |
7 |
101,049,214 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9340:Arap1
|
UTSW |
7 |
101,037,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9519:Arap1
|
UTSW |
7 |
101,043,946 (GRCm39) |
start gained |
probably benign |
|
|
R9790:Arap1
|
UTSW |
7 |
101,037,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9791:Arap1
|
UTSW |
7 |
101,037,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGGAAGACCTCATCAACCACTACG -3'
(R):5'- TGACTATGTCTGCCCTGGTACAGC -3'
Sequencing Primer
(F):5'- ACGTGGTGGTGTTCAGTG -3'
(R):5'- TGGTACAGCCTGGCTCAAC -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation