Incidental Mutation 'R7549:Phf3'
| ID |
584355 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phf3
|
| Ensembl Gene |
ENSMUSG00000048874 |
| Gene Name |
PHD finger protein 3 |
| Synonyms |
AU020177, 2310061N19Rik |
| MMRRC Submission |
045620-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7549 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
30841417-30912989 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 30870556 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Asparagine
at position 164
(T164N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000085650
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000088310]
[ENSMUST00000186733]
[ENSMUST00000188780]
[ENSMUST00000191064]
|
| AlphaFold |
B2RQG2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000088310
AA Change: T164N
PolyPhen 2
Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000085650
Gene: ENSMUSG00000048874
AA Change: T164N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000186733
AA Change: T164N
PolyPhen 2
Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000139610
Gene: ENSMUSG00000048874
AA Change: T164N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
337 |
344 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
660 |
N/A |
INTRINSIC |
|
PHD
|
697 |
748 |
3.82e-10 |
SMART |
|
low complexity region
|
847 |
859 |
N/A |
INTRINSIC |
|
low complexity region
|
876 |
887 |
N/A |
INTRINSIC |
|
TFS2M
|
908 |
1008 |
1.28e-47 |
SMART |
|
Pfam:SPOC
|
1188 |
1294 |
4.2e-26 |
PFAM |
|
low complexity region
|
1367 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1516 |
1529 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1620 |
N/A |
INTRINSIC |
|
low complexity region
|
1796 |
1811 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1846 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000188780
AA Change: T110N
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000140935
Gene: ENSMUSG00000048874
AA Change: T110N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
158 |
169 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191064
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A530084C06Rik |
G |
T |
13: 31,742,978 (GRCm39) |
R92S |
unknown |
Het |
| Adam1b |
A |
G |
5: 121,639,981 (GRCm39) |
C355R |
probably damaging |
Het |
| Adamtsl3 |
T |
C |
7: 82,223,117 (GRCm39) |
L966P |
probably damaging |
Het |
| Aldh18a1 |
A |
G |
19: 40,553,291 (GRCm39) |
C486R |
probably damaging |
Het |
| Aqp11 |
C |
A |
7: 97,387,284 (GRCm39) |
|
probably benign |
Het |
| Arhgap28 |
A |
G |
17: 68,178,961 (GRCm39) |
L350P |
probably damaging |
Het |
| Art3 |
A |
G |
5: 92,551,514 (GRCm39) |
Q291R |
probably benign |
Het |
| Asb15 |
A |
G |
6: 24,559,029 (GRCm39) |
|
probably null |
Het |
| Bmp8b |
T |
C |
4: 122,999,448 (GRCm39) |
I102T |
possibly damaging |
Het |
| Bsn |
T |
C |
9: 107,992,014 (GRCm39) |
D1246G |
probably benign |
Het |
| Cass4 |
G |
A |
2: 172,268,718 (GRCm39) |
G267S |
probably benign |
Het |
| Cass4 |
G |
T |
2: 172,268,719 (GRCm39) |
G267V |
probably benign |
Het |
| Ccr7 |
T |
C |
11: 99,036,727 (GRCm39) |
Y65C |
probably damaging |
Het |
| Clstn2 |
A |
C |
9: 97,464,597 (GRCm39) |
I186S |
probably benign |
Het |
| Cyp2r1 |
A |
G |
7: 114,153,879 (GRCm39) |
I105T |
possibly damaging |
Het |
| Efr3a |
T |
A |
15: 65,687,262 (GRCm39) |
|
probably null |
Het |
| Erg |
A |
C |
16: 95,170,179 (GRCm39) |
|
probably null |
Het |
| Eya4 |
A |
T |
10: 22,987,557 (GRCm39) |
V524E |
probably damaging |
Het |
| Farp1 |
C |
A |
14: 121,472,589 (GRCm39) |
N241K |
possibly damaging |
Het |
| Fat1 |
A |
T |
8: 45,442,031 (GRCm39) |
Y1111F |
probably benign |
Het |
| Fbn1 |
T |
C |
2: 125,185,947 (GRCm39) |
E1607G |
probably damaging |
Het |
| Fbn2 |
A |
T |
18: 58,153,536 (GRCm39) |
C2575* |
probably null |
Het |
| Fsip2 |
A |
T |
2: 82,824,337 (GRCm39) |
D6690V |
probably damaging |
Het |
| Fzd4 |
T |
C |
7: 89,056,346 (GRCm39) |
V131A |
possibly damaging |
Het |
| Gfral |
T |
A |
9: 76,106,257 (GRCm39) |
N110I |
probably benign |
Het |
| Glce |
T |
C |
9: 61,968,275 (GRCm39) |
D292G |
probably damaging |
Het |
| Gm19410 |
T |
A |
8: 36,266,500 (GRCm39) |
I1051K |
probably benign |
Het |
| Gm5773 |
A |
T |
3: 93,680,323 (GRCm39) |
|
probably benign |
Het |
| Hcn3 |
A |
T |
3: 89,057,307 (GRCm39) |
H430Q |
probably null |
Het |
| Hspa8 |
T |
A |
9: 40,714,255 (GRCm39) |
|
probably null |
Het |
| Ifna7 |
A |
T |
4: 88,734,664 (GRCm39) |
D67V |
possibly damaging |
Het |
| Kif5c |
T |
A |
2: 49,591,105 (GRCm39) |
M319K |
probably benign |
Het |
| Klk7 |
G |
T |
7: 43,462,197 (GRCm39) |
|
probably null |
Het |
| Kmt2c |
T |
C |
5: 25,619,968 (GRCm39) |
K102E |
possibly damaging |
Het |
| Krt1 |
AAGCTGCCACCCCCAAAGCCACCACCGCCGTAGCTGCCACCCCCAAAGCCACCACCGCCGTAGCTGCCACCCCCAAAGCCACCAC |
AAGCTGCCACCCCCAAAGCCACCACCGCCGTAGCTGCCACCCCCAAAGCCACCAC |
15: 101,758,813 (GRCm39) |
|
probably benign |
Het |
| Lrp1b |
C |
T |
2: 40,765,134 (GRCm39) |
M2897I |
|
Het |
| Lysmd2 |
T |
C |
9: 75,544,519 (GRCm39) |
S211P |
probably damaging |
Het |
| Magi1 |
T |
G |
6: 93,685,095 (GRCm39) |
E761A |
probably benign |
Het |
| Mbd5 |
T |
A |
2: 49,141,355 (GRCm39) |
I106N |
probably damaging |
Het |
| Mdc1 |
G |
A |
17: 36,159,749 (GRCm39) |
A669T |
probably null |
Het |
| Mmp1b |
A |
G |
9: 7,384,753 (GRCm39) |
I265T |
probably benign |
Het |
| Mmp2 |
T |
A |
8: 93,563,594 (GRCm39) |
L356Q |
probably null |
Het |
| Mroh8 |
A |
G |
2: 157,111,492 (GRCm39) |
L154P |
probably benign |
Het |
| Muc13 |
T |
C |
16: 33,619,806 (GRCm39) |
S185P |
unknown |
Het |
| Nuak1 |
T |
A |
10: 84,210,403 (GRCm39) |
I562F |
probably benign |
Het |
| Obscn |
C |
A |
11: 58,933,664 (GRCm39) |
|
probably null |
Het |
| Or51t4 |
T |
C |
7: 102,597,798 (GRCm39) |
I42T |
possibly damaging |
Het |
| Or5w14 |
A |
T |
2: 87,542,115 (GRCm39) |
M45K |
probably damaging |
Het |
| Or9k7 |
T |
C |
10: 130,046,853 (GRCm39) |
M49V |
probably benign |
Het |
| Pex3 |
T |
C |
10: 13,418,414 (GRCm39) |
M81V |
probably benign |
Het |
| Pex5l |
T |
A |
3: 33,136,184 (GRCm39) |
I12F |
probably benign |
Het |
| Phpt1 |
G |
T |
2: 25,464,844 (GRCm39) |
A3E |
probably benign |
Het |
| Pja2 |
A |
T |
17: 64,616,410 (GRCm39) |
L162M |
probably damaging |
Het |
| Pkdrej |
T |
A |
15: 85,703,994 (GRCm39) |
K647N |
probably damaging |
Het |
| Ppp2r1a |
T |
C |
17: 21,182,944 (GRCm39) |
S543P |
possibly damaging |
Het |
| Prdm13 |
C |
A |
4: 21,679,072 (GRCm39) |
D473Y |
probably damaging |
Het |
| Prl6a1 |
A |
T |
13: 27,502,954 (GRCm39) |
E183D |
probably damaging |
Het |
| Psmd3 |
C |
T |
11: 98,581,787 (GRCm39) |
T304M |
probably benign |
Het |
| Ptpn5 |
C |
T |
7: 46,735,874 (GRCm39) |
|
probably null |
Het |
| Rassf6 |
T |
G |
5: 90,754,661 (GRCm39) |
I206L |
probably damaging |
Het |
| Rif1 |
A |
G |
2: 51,968,519 (GRCm39) |
H234R |
possibly damaging |
Het |
| Rint1 |
T |
C |
5: 24,020,702 (GRCm39) |
V575A |
probably benign |
Het |
| Ros1 |
G |
A |
10: 52,021,930 (GRCm39) |
T639I |
probably damaging |
Het |
| Ryr2 |
A |
G |
13: 11,752,871 (GRCm39) |
F1817L |
probably benign |
Het |
| Ska1 |
T |
C |
18: 74,333,088 (GRCm39) |
D110G |
probably benign |
Het |
| Slc25a41 |
G |
A |
17: 57,340,791 (GRCm39) |
T227I |
probably damaging |
Het |
| Slc6a15 |
T |
C |
10: 103,224,998 (GRCm39) |
S29P |
probably benign |
Het |
| Slc8a3 |
A |
T |
12: 81,361,544 (GRCm39) |
I425K |
probably benign |
Het |
| Sox8 |
T |
A |
17: 25,786,935 (GRCm39) |
Q256L |
probably damaging |
Het |
| Tars3 |
T |
C |
7: 65,297,341 (GRCm39) |
V152A |
probably damaging |
Het |
| Tbx10 |
A |
T |
19: 4,046,651 (GRCm39) |
T44S |
probably benign |
Het |
| Terb1 |
T |
A |
8: 105,224,716 (GRCm39) |
I52F |
possibly damaging |
Het |
| Tes |
AGCCGGCC |
AGCC |
6: 17,099,740 (GRCm39) |
|
probably null |
Het |
| Tgm1 |
A |
G |
14: 55,943,360 (GRCm39) |
V527A |
probably benign |
Het |
| Tmed10 |
G |
T |
12: 85,391,036 (GRCm39) |
Y167* |
probably null |
Het |
| Tmem165 |
T |
G |
5: 76,356,415 (GRCm39) |
S318R |
possibly damaging |
Het |
| Trim9 |
G |
T |
12: 70,393,715 (GRCm39) |
S76R |
probably damaging |
Het |
| Tti1 |
A |
G |
2: 157,849,088 (GRCm39) |
V717A |
probably damaging |
Het |
| Vmn2r86 |
T |
A |
10: 130,282,697 (GRCm39) |
I640F |
probably damaging |
Het |
| Vwf |
A |
G |
6: 125,603,230 (GRCm39) |
N860S |
|
Het |
| Xirp2 |
A |
G |
2: 67,339,241 (GRCm39) |
K494R |
possibly damaging |
Het |
| Zkscan4 |
G |
A |
13: 21,668,419 (GRCm39) |
S319N |
probably damaging |
Het |
|
| Other mutations in Phf3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00234:Phf3
|
APN |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00704:Phf3
|
APN |
1 |
30,843,919 (GRCm39) |
missense |
probably benign |
|
|
IGL01147:Phf3
|
APN |
1 |
30,843,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01360:Phf3
|
APN |
1 |
30,847,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01376:Phf3
|
APN |
1 |
30,869,566 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01396:Phf3
|
APN |
1 |
30,843,386 (GRCm39) |
nonsense |
probably null |
|
|
IGL01830:Phf3
|
APN |
1 |
30,853,148 (GRCm39) |
nonsense |
probably null |
|
|
IGL02108:Phf3
|
APN |
1 |
30,869,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02156:Phf3
|
APN |
1 |
30,847,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02576:Phf3
|
APN |
1 |
30,869,117 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03031:Phf3
|
APN |
1 |
30,843,734 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03334:Phf3
|
APN |
1 |
30,844,810 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03411:Phf3
|
APN |
1 |
30,843,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4976:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
utr 3 prime |
probably benign |
|
|
PIT4458001:Phf3
|
UTSW |
1 |
30,855,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Phf3
|
UTSW |
1 |
30,843,999 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0052:Phf3
|
UTSW |
1 |
30,847,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0114:Phf3
|
UTSW |
1 |
30,844,524 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0123:Phf3
|
UTSW |
1 |
30,844,146 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0225:Phf3
|
UTSW |
1 |
30,844,146 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0715:Phf3
|
UTSW |
1 |
30,850,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0835:Phf3
|
UTSW |
1 |
30,869,632 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0848:Phf3
|
UTSW |
1 |
30,902,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Phf3
|
UTSW |
1 |
30,845,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1522:Phf3
|
UTSW |
1 |
30,844,729 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1549:Phf3
|
UTSW |
1 |
30,843,923 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1555:Phf3
|
UTSW |
1 |
30,844,958 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1780:Phf3
|
UTSW |
1 |
30,851,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Phf3
|
UTSW |
1 |
30,845,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Phf3
|
UTSW |
1 |
30,869,704 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1912:Phf3
|
UTSW |
1 |
30,843,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1957:Phf3
|
UTSW |
1 |
30,870,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2019:Phf3
|
UTSW |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2259:Phf3
|
UTSW |
1 |
30,843,424 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2305:Phf3
|
UTSW |
1 |
30,844,556 (GRCm39) |
nonsense |
probably null |
|
|
R2345:Phf3
|
UTSW |
1 |
30,844,432 (GRCm39) |
nonsense |
probably null |
|
|
R2424:Phf3
|
UTSW |
1 |
30,845,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2497:Phf3
|
UTSW |
1 |
30,869,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Phf3
|
UTSW |
1 |
30,849,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3522:Phf3
|
UTSW |
1 |
30,844,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3816:Phf3
|
UTSW |
1 |
30,844,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Phf3
|
UTSW |
1 |
30,870,539 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4403:Phf3
|
UTSW |
1 |
30,843,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4658:Phf3
|
UTSW |
1 |
30,902,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Phf3
|
UTSW |
1 |
30,860,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4669:Phf3
|
UTSW |
1 |
30,869,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4706:Phf3
|
UTSW |
1 |
30,844,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4757:Phf3
|
UTSW |
1 |
30,859,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4766:Phf3
|
UTSW |
1 |
30,853,020 (GRCm39) |
unclassified |
probably benign |
|
|
R4786:Phf3
|
UTSW |
1 |
30,855,638 (GRCm39) |
nonsense |
probably null |
|
|
R5107:Phf3
|
UTSW |
1 |
30,870,566 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5155:Phf3
|
UTSW |
1 |
30,863,457 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5310:Phf3
|
UTSW |
1 |
30,842,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5823:Phf3
|
UTSW |
1 |
30,843,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5944:Phf3
|
UTSW |
1 |
30,859,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5979:Phf3
|
UTSW |
1 |
30,844,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6007:Phf3
|
UTSW |
1 |
30,843,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Phf3
|
UTSW |
1 |
30,902,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6072:Phf3
|
UTSW |
1 |
30,869,769 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6533:Phf3
|
UTSW |
1 |
30,845,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6649:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6653:Phf3
|
UTSW |
1 |
30,844,104 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6852:Phf3
|
UTSW |
1 |
30,843,711 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6855:Phf3
|
UTSW |
1 |
30,859,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6862:Phf3
|
UTSW |
1 |
30,853,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6930:Phf3
|
UTSW |
1 |
30,850,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7135:Phf3
|
UTSW |
1 |
30,870,190 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7323:Phf3
|
UTSW |
1 |
30,852,211 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7352:Phf3
|
UTSW |
1 |
30,843,407 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7455:Phf3
|
UTSW |
1 |
30,876,239 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7609:Phf3
|
UTSW |
1 |
30,844,582 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7720:Phf3
|
UTSW |
1 |
30,868,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7745:Phf3
|
UTSW |
1 |
30,843,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8134:Phf3
|
UTSW |
1 |
30,863,552 (GRCm39) |
missense |
unknown |
|
|
R8264:Phf3
|
UTSW |
1 |
30,870,138 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8545:Phf3
|
UTSW |
1 |
30,863,391 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8821:Phf3
|
UTSW |
1 |
30,860,347 (GRCm39) |
nonsense |
probably null |
|
|
R8831:Phf3
|
UTSW |
1 |
30,860,347 (GRCm39) |
nonsense |
probably null |
|
|
R8873:Phf3
|
UTSW |
1 |
30,843,773 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R9101:Phf3
|
UTSW |
1 |
30,843,026 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9402:Phf3
|
UTSW |
1 |
30,850,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9426:Phf3
|
UTSW |
1 |
30,870,625 (GRCm39) |
nonsense |
probably null |
|
|
R9594:Phf3
|
UTSW |
1 |
30,869,003 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9707:Phf3
|
UTSW |
1 |
30,868,923 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9803:Phf3
|
UTSW |
1 |
30,869,872 (GRCm39) |
missense |
probably benign |
0.16 |
|
Z1177:Phf3
|
UTSW |
1 |
30,851,049 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,844,132 (GRCm39) |
missense |
unknown |
|
|
Z1177:Phf3
|
UTSW |
1 |
30,843,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGGGATCAAACTCAGCCTC -3'
(R):5'- TGATCAGGTAAGTTTCAGATGTCAG -3'
Sequencing Primer
(F):5'- TCCTTCATTCCAGCACAAGACG -3'
(R):5'- GGTAAGTTTCAGATGTCAGAATAAGG -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation