Incidental Mutation 'R7567:Kirrel1'
| ID |
585488 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kirrel1
|
| Ensembl Gene |
ENSMUSG00000041734 |
| Gene Name |
kirre like nephrin family adhesion molecule 1 |
| Synonyms |
6720469N11Rik, Neph1, Kirrel1, Kirrel |
| MMRRC Submission |
045629-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7567 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
86985900-87082054 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 87002988 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Lysine
at position 135
(T135K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041732]
[ENSMUST00000107618]
[ENSMUST00000159976]
|
| AlphaFold |
Q80W68 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041732
AA Change: T135K
PolyPhen 2
Score 0.975 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000043756
Gene: ENSMUSG00000041734
AA Change: T135K
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107618
AA Change: T135K
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000103243
Gene: ENSMUSG00000041734
AA Change: T135K
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000159976
AA Change: T135K
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000125525
Gene: ENSMUSG00000041734
AA Change: T135K
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit postnatal lethality and are small and sickly. Glomerular and tubular defects in the kidney result in severe proteinuria. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(121) : Targeted, other(2) Gene trapped(119) |
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
A |
T |
17: 9,226,838 (GRCm39) |
Q464H |
probably damaging |
Het |
| Abcc5 |
A |
T |
16: 20,224,260 (GRCm39) |
S108T |
probably damaging |
Het |
| Acss3 |
T |
C |
10: 106,959,174 (GRCm39) |
S91G |
probably benign |
Het |
| Adgrf4 |
T |
A |
17: 42,978,333 (GRCm39) |
I337L |
probably benign |
Het |
| Adgrv1 |
A |
G |
13: 81,581,648 (GRCm39) |
S4799P |
probably benign |
Het |
| Adgrv1 |
T |
C |
13: 81,727,596 (GRCm39) |
D348G |
probably damaging |
Het |
| Afdn |
A |
G |
17: 14,109,070 (GRCm39) |
D1546G |
probably benign |
Het |
| Agr2 |
A |
T |
12: 36,045,946 (GRCm39) |
R64S |
probably benign |
Het |
| Ankrd13a |
T |
A |
5: 114,927,545 (GRCm39) |
|
probably null |
Het |
| Apon |
T |
A |
10: 128,090,922 (GRCm39) |
M200K |
possibly damaging |
Het |
| Art4 |
T |
C |
6: 136,831,428 (GRCm39) |
S238G |
possibly damaging |
Het |
| Atp2a2 |
A |
T |
5: 122,629,847 (GRCm39) |
V74D |
probably benign |
Het |
| Atrnl1 |
T |
C |
19: 57,687,955 (GRCm39) |
S807P |
probably damaging |
Het |
| C2cd3 |
T |
C |
7: 100,080,022 (GRCm39) |
V936A |
|
Het |
| Car15 |
T |
A |
16: 17,654,652 (GRCm39) |
H122L |
probably damaging |
Het |
| Cav3 |
A |
T |
6: 112,449,428 (GRCm39) |
R149W |
probably benign |
Het |
| Ccdc8 |
A |
T |
7: 16,728,687 (GRCm39) |
I59F |
probably damaging |
Het |
| Ccng2 |
G |
A |
5: 93,418,731 (GRCm39) |
V119I |
probably benign |
Het |
| Ceacam2 |
A |
G |
7: 25,227,333 (GRCm39) |
I178T |
probably benign |
Het |
| Ces2a |
A |
G |
8: 105,467,930 (GRCm39) |
D520G |
probably benign |
Het |
| Cln8 |
T |
C |
8: 14,945,057 (GRCm39) |
S124P |
probably benign |
Het |
| Coro2a |
T |
A |
4: 46,546,674 (GRCm39) |
D227V |
probably damaging |
Het |
| Cpa4 |
A |
C |
6: 30,573,889 (GRCm39) |
R32S |
probably benign |
Het |
| Creb3l4 |
G |
T |
3: 90,149,729 (GRCm39) |
D45E |
probably benign |
Het |
| Crybb2 |
C |
T |
5: 113,213,759 (GRCm39) |
|
probably null |
Het |
| Cul7 |
T |
A |
17: 46,965,521 (GRCm39) |
H566Q |
probably benign |
Het |
| Cyp2b10 |
A |
G |
7: 25,614,204 (GRCm39) |
Y226C |
probably damaging |
Het |
| Dennd2a |
A |
T |
6: 39,499,743 (GRCm39) |
V274D |
probably benign |
Het |
| Dmbt1 |
G |
A |
7: 130,663,093 (GRCm39) |
|
probably null |
Het |
| Drc7 |
T |
C |
8: 95,794,684 (GRCm39) |
I363T |
probably benign |
Het |
| Drd3 |
G |
A |
16: 43,643,047 (GRCm39) |
V396I |
probably benign |
Het |
| Dync2i1 |
A |
T |
12: 116,218,130 (GRCm39) |
|
probably null |
Het |
| Eif2ak4 |
A |
G |
2: 118,280,795 (GRCm39) |
N1054S |
probably benign |
Het |
| Epc1 |
A |
C |
18: 6,450,084 (GRCm39) |
V458G |
probably damaging |
Het |
| Exoc1 |
T |
A |
5: 76,685,562 (GRCm39) |
D91E |
probably damaging |
Het |
| Fat4 |
T |
A |
3: 38,943,485 (GRCm39) |
F793I |
probably damaging |
Het |
| Fhod1 |
T |
C |
8: 106,074,469 (GRCm39) |
E6G |
unknown |
Het |
| Galnt16 |
G |
A |
12: 80,628,084 (GRCm39) |
|
probably null |
Het |
| Ganc |
A |
T |
2: 120,286,582 (GRCm39) |
T804S |
probably benign |
Het |
| Gpam |
A |
T |
19: 55,070,062 (GRCm39) |
V398E |
possibly damaging |
Het |
| Gpr68 |
A |
G |
12: 100,844,623 (GRCm39) |
V307A |
probably benign |
Het |
| Grm7 |
C |
T |
6: 111,335,722 (GRCm39) |
S711L |
probably damaging |
Het |
| Hemgn |
T |
A |
4: 46,397,034 (GRCm39) |
R67S |
probably damaging |
Het |
| Hmg20b |
T |
C |
10: 81,182,493 (GRCm39) |
D281G |
possibly damaging |
Het |
| Ifi211 |
A |
C |
1: 173,729,401 (GRCm39) |
F277V |
probably damaging |
Het |
| Ighmbp2 |
T |
C |
19: 3,322,981 (GRCm39) |
I322V |
probably benign |
Het |
| Iqce |
A |
T |
5: 140,671,830 (GRCm39) |
L265H |
probably damaging |
Het |
| Itgal |
G |
T |
7: 126,898,960 (GRCm39) |
A101S |
probably benign |
Het |
| Kif5a |
C |
T |
10: 127,073,248 (GRCm39) |
M647I |
probably benign |
Het |
| Klf16 |
T |
C |
10: 80,412,622 (GRCm39) |
Y138C |
probably benign |
Het |
| Klhl7 |
A |
G |
5: 24,331,844 (GRCm39) |
T49A |
probably benign |
Het |
| Mr1 |
T |
C |
1: 155,022,474 (GRCm39) |
|
probably benign |
Het |
| Mrc1 |
A |
T |
2: 14,330,104 (GRCm39) |
I1238F |
probably damaging |
Het |
| Ncoa5 |
C |
T |
2: 164,846,171 (GRCm39) |
M225I |
possibly damaging |
Het |
| Nf1 |
A |
T |
11: 79,438,052 (GRCm39) |
T121S |
probably damaging |
Het |
| Ngfr |
T |
C |
11: 95,465,147 (GRCm39) |
T234A |
probably benign |
Het |
| Ninj1 |
T |
G |
13: 49,347,356 (GRCm39) |
F74V |
probably damaging |
Het |
| Npffr1 |
T |
C |
10: 61,462,088 (GRCm39) |
V408A |
probably benign |
Het |
| Nsd2 |
T |
C |
5: 34,003,570 (GRCm39) |
V240A |
probably damaging |
Het |
| Obi1 |
T |
C |
14: 104,716,814 (GRCm39) |
T520A |
probably damaging |
Het |
| Or12d13 |
T |
A |
17: 37,648,062 (GRCm39) |
E20D |
probably benign |
Het |
| Or2z2 |
A |
G |
11: 58,345,992 (GRCm39) |
M261T |
probably damaging |
Het |
| Or7a35 |
T |
A |
10: 78,853,379 (GRCm39) |
F74L |
probably benign |
Het |
| Or8b44 |
G |
A |
9: 38,410,369 (GRCm39) |
V135I |
probably benign |
Het |
| Or8g34 |
T |
C |
9: 39,373,173 (GRCm39) |
S146P |
possibly damaging |
Het |
| Ovol1 |
T |
C |
19: 5,601,614 (GRCm39) |
H136R |
probably damaging |
Het |
| Prag1 |
T |
A |
8: 36,569,760 (GRCm39) |
D114E |
possibly damaging |
Het |
| Pramel17 |
T |
C |
4: 101,694,331 (GRCm39) |
N184S |
probably benign |
Het |
| Prss3b |
C |
A |
6: 41,010,127 (GRCm39) |
R69L |
probably benign |
Het |
| Prss57 |
T |
A |
10: 79,623,234 (GRCm39) |
H71L |
probably benign |
Het |
| Ptgs2 |
T |
C |
1: 149,978,448 (GRCm39) |
F187L |
probably damaging |
Het |
| Ptprz1 |
A |
T |
6: 22,959,779 (GRCm39) |
N92I |
probably damaging |
Het |
| Rab23 |
A |
T |
1: 33,773,812 (GRCm39) |
T91S |
possibly damaging |
Het |
| Rag1 |
A |
G |
2: 101,474,006 (GRCm39) |
S379P |
probably damaging |
Het |
| Ribc2 |
G |
T |
15: 85,027,448 (GRCm39) |
D310Y |
probably damaging |
Het |
| Rims1 |
A |
G |
1: 22,507,291 (GRCm39) |
Y620H |
probably damaging |
Het |
| Rock1 |
A |
C |
18: 10,090,820 (GRCm39) |
V938G |
probably benign |
Het |
| Rsph10b |
A |
G |
5: 143,886,244 (GRCm39) |
N314S |
possibly damaging |
Het |
| Sertad1 |
A |
G |
7: 27,189,327 (GRCm39) |
D216G |
possibly damaging |
Het |
| Shisal1 |
G |
A |
15: 84,290,914 (GRCm39) |
T131M |
probably benign |
Het |
| Slco6d1 |
T |
A |
1: 98,425,252 (GRCm39) |
V600D |
probably damaging |
Het |
| Snapc2 |
T |
C |
8: 4,305,314 (GRCm39) |
I232T |
probably damaging |
Het |
| Snx13 |
A |
G |
12: 35,136,913 (GRCm39) |
S125G |
probably damaging |
Het |
| Srcin1 |
C |
T |
11: 97,425,551 (GRCm39) |
R502H |
probably damaging |
Het |
| Tesmin |
A |
G |
19: 3,442,218 (GRCm39) |
E167G |
possibly damaging |
Het |
| Tex10 |
T |
C |
4: 48,468,787 (GRCm39) |
I129M |
possibly damaging |
Het |
| Tmem235 |
A |
G |
11: 117,754,967 (GRCm39) |
S140G |
probably benign |
Het |
| Trim60 |
T |
A |
8: 65,454,177 (GRCm39) |
D24V |
probably damaging |
Het |
| Ttc39c |
A |
G |
18: 12,822,936 (GRCm39) |
E148G |
probably benign |
Het |
| Vmn2r70 |
G |
T |
7: 85,214,243 (GRCm39) |
T303K |
probably benign |
Het |
| Wdr48 |
A |
T |
9: 119,745,894 (GRCm39) |
T426S |
possibly damaging |
Het |
| Xirp2 |
A |
T |
2: 67,346,326 (GRCm39) |
T2856S |
probably benign |
Het |
| Zswim8 |
A |
G |
14: 20,770,001 (GRCm39) |
N1356S |
probably damaging |
Het |
|
| Other mutations in Kirrel1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01310:Kirrel1
|
APN |
3 |
86,997,182 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01865:Kirrel1
|
APN |
3 |
86,993,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Kirrel1
|
APN |
3 |
87,003,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02337:Kirrel1
|
APN |
3 |
86,996,519 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02724:Kirrel1
|
APN |
3 |
86,997,780 (GRCm39) |
nonsense |
probably null |
|
|
IGL02825:Kirrel1
|
APN |
3 |
86,996,595 (GRCm39) |
splice site |
probably benign |
|
|
IGL02826:Kirrel1
|
APN |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Kirrel1
|
APN |
3 |
86,990,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
D4043:Kirrel1
|
UTSW |
3 |
86,990,510 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0360:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0421:Kirrel1
|
UTSW |
3 |
86,990,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0503:Kirrel1
|
UTSW |
3 |
87,005,109 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1112:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1116:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1144:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1190:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1226:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1501:Kirrel1
|
UTSW |
3 |
86,997,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1538:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1546:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1628:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1630:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1631:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1664:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1671:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1695:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1769:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1807:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1808:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1840:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1995:Kirrel1
|
UTSW |
3 |
87,003,093 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2014:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2086:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2108:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2354:Kirrel1
|
UTSW |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2407:Kirrel1
|
UTSW |
3 |
86,992,150 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2904:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2905:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2958:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2959:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2960:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2961:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3026:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3028:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3034:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3149:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3195:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3196:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3499:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3699:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3720:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3721:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3788:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3793:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3877:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3901:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3910:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3911:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3912:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3913:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3930:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3931:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4022:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4067:Kirrel1
|
UTSW |
3 |
86,995,774 (GRCm39) |
nonsense |
probably null |
|
|
R4077:Kirrel1
|
UTSW |
3 |
86,992,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4198:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4328:Kirrel1
|
UTSW |
3 |
86,992,081 (GRCm39) |
intron |
probably benign |
|
|
R4355:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4363:Kirrel1
|
UTSW |
3 |
86,997,792 (GRCm39) |
nonsense |
probably null |
|
|
R4378:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4386:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4460:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4468:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4469:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4650:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4652:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4734:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4748:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4749:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R5304:Kirrel1
|
UTSW |
3 |
86,996,902 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5534:Kirrel1
|
UTSW |
3 |
86,997,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Kirrel1
|
UTSW |
3 |
86,996,462 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7199:Kirrel1
|
UTSW |
3 |
86,990,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7221:Kirrel1
|
UTSW |
3 |
86,993,704 (GRCm39) |
nonsense |
probably null |
|
|
R7284:Kirrel1
|
UTSW |
3 |
86,990,694 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7332:Kirrel1
|
UTSW |
3 |
86,995,705 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7369:Kirrel1
|
UTSW |
3 |
87,048,391 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7371:Kirrel1
|
UTSW |
3 |
86,995,729 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7508:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7566:Kirrel1
|
UTSW |
3 |
86,995,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7621:Kirrel1
|
UTSW |
3 |
86,995,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8030:Kirrel1
|
UTSW |
3 |
87,005,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8141:Kirrel1
|
UTSW |
3 |
86,993,735 (GRCm39) |
nonsense |
probably null |
|
|
R8261:Kirrel1
|
UTSW |
3 |
86,995,309 (GRCm39) |
intron |
probably benign |
|
|
R8477:Kirrel1
|
UTSW |
3 |
86,992,138 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8512:Kirrel1
|
UTSW |
3 |
86,995,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8954:Kirrel1
|
UTSW |
3 |
86,997,173 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8987:Kirrel1
|
UTSW |
3 |
86,992,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kirrel1
|
UTSW |
3 |
86,992,442 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9146:Kirrel1
|
UTSW |
3 |
87,003,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Kirrel1
|
UTSW |
3 |
87,005,123 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9527:Kirrel1
|
UTSW |
3 |
86,996,912 (GRCm39) |
nonsense |
probably null |
|
|
R9629:Kirrel1
|
UTSW |
3 |
87,003,025 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Kirrel1
|
UTSW |
3 |
86,991,182 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCCTAGTTGATGATGAAGTTCATG -3'
(R):5'- TCTGCTGTGAGGAGAAGCTG -3'
Sequencing Primer
(F):5'- ATGAAGTTCATGTAAGGAGTTGC -3'
(R):5'- ACAATGAGTCTTGGGTGGAG -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation