Incidental Mutation 'R0055:Slfn10-ps'
ID 58978
Institutional Source Beutler Lab
Gene Symbol Slfn10-ps
Ensembl Gene ENSMUSG00000072621
Gene Name schlafen 10, pseudogene
Synonyms
MMRRC Submission 038349-MU
Accession Numbers
Essential gene? Probably non essential (E-score: 0.073) question?
Stock # R0055 (G1)
Quality Score 225
Status Validated
Chromosome 11
Chromosomal Location 82919681-82926992 bp(-) (GRCm39)
Type of Mutation unclassified
DNA Base Change (assembly) A to G at 82921126 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000100716
SMART Domains Protein: ENSMUSP00000098282
Gene: ENSMUSG00000072621

DomainStartEndE-ValueType
Pfam:AlbA_2 142 278 1.3e-13 PFAM
Pfam:DUF2075 529 697 1.6e-7 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000119608
Predicted Effect noncoding transcript
Transcript: ENSMUST00000152760
SMART Domains Protein: ENSMUSP00000130353
Gene: ENSMUSG00000072621

DomainStartEndE-ValueType
Pfam:AAA_4 142 280 1.8e-14 PFAM
Pfam:DUF2075 529 693 1.8e-8 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000185158
Meta Mutation Damage Score 0.3021 question?
Coding Region Coverage
  • 1x: 99.4%
  • 3x: 98.9%
  • 10x: 97.6%
  • 20x: 95.6%
Validation Efficiency 98% (59/60)
Allele List at MGI
Other mutations in this stock
Total: 57 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A2ml1 T C 6: 128,547,057 (GRCm39) probably benign Het
Atp6v1h A T 1: 5,154,677 (GRCm39) T2S probably benign Het
Bcl11b G A 12: 107,932,036 (GRCm39) P179S probably benign Het
Cacna1a C T 8: 85,306,687 (GRCm39) probably benign Het
Ccdc146 C T 5: 21,502,004 (GRCm39) probably null Het
Ccdc61 T C 7: 18,626,461 (GRCm39) D128G probably damaging Het
Cd55 A G 1: 130,387,313 (GRCm39) probably benign Het
Cdk7 C A 13: 100,855,812 (GRCm39) E99* probably null Het
Cfap96 A T 8: 46,421,198 (GRCm39) S108R probably damaging Het
Cox8a A T 19: 7,194,874 (GRCm39) S2T probably damaging Het
Cracdl A C 1: 37,663,337 (GRCm39) S854A probably benign Het
Dennd5a A G 7: 109,498,998 (GRCm39) I955T possibly damaging Het
Dop1a A C 9: 86,394,705 (GRCm39) E602A probably benign Het
Ephx4 T C 5: 107,560,944 (GRCm39) L32S probably damaging Het
Fbxo21 T A 5: 118,138,555 (GRCm39) D493E probably benign Het
Frmd4b A T 6: 97,300,610 (GRCm39) probably benign Het
Fzd1 A T 5: 4,806,037 (GRCm39) M515K possibly damaging Het
Gli2 A G 1: 118,818,138 (GRCm39) probably benign Het
Gm12887 T A 4: 121,473,666 (GRCm39) K61N probably damaging Het
Grin2a A T 16: 9,487,671 (GRCm39) V409D probably damaging Het
Grin2b T C 6: 135,900,201 (GRCm39) I227V probably benign Het
Helz2 T G 2: 180,870,614 (GRCm39) D2879A possibly damaging Het
Itpr2 T C 6: 146,224,631 (GRCm39) N1453S probably benign Het
Itpr3 C A 17: 27,317,296 (GRCm39) S817Y probably damaging Het
Lin7c T A 2: 109,726,798 (GRCm39) probably benign Het
Ly75 T C 2: 60,152,262 (GRCm39) E1097G probably benign Het
Mcm10 T C 2: 4,996,218 (GRCm39) N882D probably damaging Het
Mettl13 A T 1: 162,373,750 (GRCm39) L167Q probably damaging Het
Morn2 A T 17: 80,602,942 (GRCm39) M1L probably benign Het
Mybph G T 1: 134,121,590 (GRCm39) V88L probably damaging Het
Nefm T A 14: 68,358,648 (GRCm39) probably benign Het
Nf1 A G 11: 79,362,377 (GRCm39) E1497G probably damaging Het
Or2j3 T C 17: 38,615,702 (GRCm39) S217G possibly damaging Het
Or4k37 T A 2: 111,158,870 (GRCm39) Y35* probably null Het
Or51ah3 A G 7: 103,210,244 (GRCm39) K187E probably damaging Het
Or52e18 T A 7: 104,609,703 (GRCm39) T79S possibly damaging Het
Phf8-ps A T 17: 33,285,696 (GRCm39) W369R probably damaging Het
Plcd3 C G 11: 102,968,411 (GRCm39) W382S probably damaging Het
Plxna1 T A 6: 89,306,721 (GRCm39) I1370F possibly damaging Het
Qng1 T C 13: 58,531,980 (GRCm39) D192G probably damaging Het
Rarb G A 14: 16,509,066 (GRCm38) R106C probably damaging Het
Rps6ka5 G A 12: 100,644,839 (GRCm39) T37I probably damaging Het
Runx1 G T 16: 92,441,029 (GRCm39) probably benign Het
Scube1 A G 15: 83,518,937 (GRCm39) V301A probably damaging Het
Sema3a A T 5: 13,450,004 (GRCm39) N27I possibly damaging Het
Slc15a3 G T 19: 10,820,406 (GRCm39) E8* probably null Het
Slc22a5 T C 11: 53,782,032 (GRCm39) S112G probably benign Het
Slc25a45 T C 19: 5,930,495 (GRCm39) F3L probably damaging Het
Slc4a4 A C 5: 89,304,195 (GRCm39) H502P possibly damaging Het
Slit2 C A 5: 48,439,068 (GRCm39) C1077* probably null Het
Spn A G 7: 126,735,494 (GRCm39) F82L possibly damaging Het
Tbccd1 A G 16: 22,660,655 (GRCm39) W54R probably damaging Het
Ucp1 G T 8: 84,017,233 (GRCm39) E8* probably null Het
Unc80 A T 1: 66,545,782 (GRCm39) probably benign Het
Vsnl1 A T 12: 11,436,987 (GRCm39) probably null Het
Zdhhc11 C T 13: 74,130,805 (GRCm39) Q295* probably null Het
Zfp457 T A 13: 67,442,098 (GRCm39) H63L probably damaging Het
Other mutations in Slfn10-ps
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00773:Slfn10-ps APN 11 82,926,355 (GRCm39) unclassified noncoding transcript
IGL00826:Slfn10-ps APN 11 82,926,085 (GRCm39) unclassified noncoding transcript
IGL01022:Slfn10-ps APN 11 82,926,353 (GRCm39) unclassified noncoding transcript
IGL01409:Slfn10-ps APN 11 82,926,322 (GRCm39) unclassified noncoding transcript
IGL01664:Slfn10-ps APN 11 82,926,761 (GRCm39) unclassified noncoding transcript
IGL01700:Slfn10-ps APN 11 82,919,938 (GRCm39) unclassified noncoding transcript
IGL02093:Slfn10-ps APN 11 82,923,016 (GRCm39) unclassified noncoding transcript
IGL02253:Slfn10-ps APN 11 82,919,890 (GRCm39) unclassified noncoding transcript
IGL02364:Slfn10-ps APN 11 82,923,117 (GRCm39) unclassified noncoding transcript
IGL02466:Slfn10-ps APN 11 82,921,090 (GRCm39) unclassified noncoding transcript
IGL02636:Slfn10-ps APN 11 82,920,971 (GRCm39) unclassified noncoding transcript
R0055:Slfn10-ps UTSW 11 82,921,126 (GRCm39) unclassified noncoding transcript
R0069:Slfn10-ps UTSW 11 82,926,368 (GRCm39) unclassified noncoding transcript
R0069:Slfn10-ps UTSW 11 82,926,368 (GRCm39) unclassified noncoding transcript
R0164:Slfn10-ps UTSW 11 82,926,128 (GRCm39) unclassified noncoding transcript
R0362:Slfn10-ps UTSW 11 82,926,600 (GRCm39) unclassified noncoding transcript
R0382:Slfn10-ps UTSW 11 82,920,360 (GRCm39) unclassified noncoding transcript
R0597:Slfn10-ps UTSW 11 82,926,479 (GRCm39) unclassified noncoding transcript
R0812:Slfn10-ps UTSW 11 82,926,388 (GRCm39) unclassified noncoding transcript
R0904:Slfn10-ps UTSW 11 82,926,235 (GRCm39) unclassified noncoding transcript
R1552:Slfn10-ps UTSW 11 82,920,676 (GRCm39) unclassified noncoding transcript
R1703:Slfn10-ps UTSW 11 82,920,869 (GRCm39) unclassified noncoding transcript
R2127:Slfn10-ps UTSW 11 82,921,168 (GRCm39) unclassified noncoding transcript
R2151:Slfn10-ps UTSW 11 82,926,511 (GRCm39) unclassified noncoding transcript
R2302:Slfn10-ps UTSW 11 82,919,756 (GRCm39) unclassified noncoding transcript
R3114:Slfn10-ps UTSW 11 82,919,955 (GRCm39) unclassified noncoding transcript
R4293:Slfn10-ps UTSW 11 82,926,260 (GRCm39) unclassified noncoding transcript
R4929:Slfn10-ps UTSW 11 82,920,345 (GRCm39) unclassified noncoding transcript
R4970:Slfn10-ps UTSW 11 82,921,207 (GRCm39) unclassified noncoding transcript
R5083:Slfn10-ps UTSW 11 82,921,341 (GRCm39) unclassified noncoding transcript
R5290:Slfn10-ps UTSW 11 82,919,851 (GRCm39) unclassified noncoding transcript
R5306:Slfn10-ps UTSW 11 82,926,355 (GRCm39) unclassified noncoding transcript
R5444:Slfn10-ps UTSW 11 82,926,113 (GRCm39) unclassified noncoding transcript
Predicted Primers PCR Primer
(F):5'- GGCAAGCCATGCACAAATAGTTCTC -3'
(R):5'- TTTTCATGTCCAGTGTCACCAGACC -3'

Sequencing Primer
(F):5'- CTGGTCGCTCAAGAAAGATCTG -3'
(R):5'- TCCAGTGTCACCAGACCATTTAAAG -3'
Posted On 2013-07-11