Incidental Mutation 'R0683:Ncoa4-ps'
| ID |
61055 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ncoa4-ps
|
| Ensembl Gene |
ENSMUSG00000021908 |
| Gene Name |
nuclear receptor coactivator 4, pseudogene |
| Synonyms |
Gm6768 |
| MMRRC Submission |
038868-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.374)
|
| Stock # |
R0683 (G1)
|
| Quality Score |
115 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
119224713-119226590 bp(+) (GRCm39) |
| Type of Mutation |
exon |
| DNA Base Change (assembly) |
T to C
at 119224813 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000022467
|
| SMART Domains |
Protein: ENSMUSP00000136708
Gene: ENSMUSG00000021908
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ARA70
|
33 |
169 |
2.4e-28 |
PFAM |
|
Pfam:ARA70
|
199 |
334 |
4.7e-51 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 94.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 25 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ahdc1 |
T |
C |
4: 132,792,827 (GRCm39) |
F1356S |
possibly damaging |
Het |
| Atg16l2 |
T |
C |
7: 100,939,591 (GRCm39) |
D533G |
probably damaging |
Het |
| Camta1 |
C |
A |
4: 151,159,597 (GRCm39) |
R1614L |
probably damaging |
Het |
| Eif3i |
G |
T |
4: 129,487,328 (GRCm39) |
N162K |
probably benign |
Het |
| Exoc8 |
A |
G |
8: 125,622,372 (GRCm39) |
I665T |
probably damaging |
Het |
| Ggt7 |
A |
G |
2: 155,348,428 (GRCm39) |
S75P |
probably benign |
Het |
| Gjd3 |
A |
T |
11: 102,691,237 (GRCm39) |
F255L |
probably benign |
Het |
| Krt1 |
A |
G |
15: 101,758,901 (GRCm39) |
F88L |
unknown |
Het |
| Maml3 |
G |
A |
3: 51,764,173 (GRCm39) |
Q264* |
probably null |
Het |
| Neu1 |
A |
T |
17: 35,153,301 (GRCm39) |
|
probably null |
Het |
| Nrp2 |
A |
G |
1: 62,783,477 (GRCm39) |
T193A |
probably benign |
Het |
| Or4c12b |
C |
G |
2: 89,647,522 (GRCm39) |
P278R |
probably damaging |
Het |
| P4ha1 |
A |
G |
10: 59,172,969 (GRCm39) |
T23A |
probably benign |
Het |
| Pgm1 |
A |
G |
4: 99,818,740 (GRCm39) |
I112V |
probably damaging |
Het |
| Ptprs |
A |
T |
17: 56,721,086 (GRCm39) |
V1385D |
probably damaging |
Het |
| Rasal2 |
A |
G |
1: 157,006,779 (GRCm39) |
S111P |
probably damaging |
Het |
| Serpinb13 |
A |
G |
1: 106,926,751 (GRCm39) |
N249S |
probably damaging |
Het |
| Sh3pxd2a |
T |
C |
19: 47,255,950 (GRCm39) |
T923A |
probably benign |
Het |
| Speg |
G |
A |
1: 75,405,762 (GRCm39) |
A2989T |
probably damaging |
Het |
| Stard9 |
C |
A |
2: 120,504,117 (GRCm39) |
S221R |
probably damaging |
Het |
| Tcp11l1 |
A |
T |
2: 104,512,237 (GRCm39) |
V465E |
possibly damaging |
Het |
| Ttn |
G |
A |
2: 76,768,653 (GRCm39) |
T2973I |
unknown |
Het |
| Vav3 |
C |
A |
3: 109,559,129 (GRCm39) |
Q110K |
probably benign |
Het |
| Xcr1 |
T |
C |
9: 123,684,940 (GRCm39) |
D274G |
probably benign |
Het |
| Zfp763 |
G |
A |
17: 33,237,892 (GRCm39) |
P418S |
probably damaging |
Het |
|
| Other mutations in Ncoa4-ps |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01778:Ncoa4-ps
|
APN |
12 |
119,226,231 (GRCm39) |
exon |
noncoding transcript |
|
|
R1186:Ncoa4-ps
|
UTSW |
12 |
119,225,206 (GRCm39) |
exon |
noncoding transcript |
|
|
R1485:Ncoa4-ps
|
UTSW |
12 |
119,224,785 (GRCm39) |
exon |
noncoding transcript |
|
|
R1708:Ncoa4-ps
|
UTSW |
12 |
119,225,968 (GRCm39) |
exon |
noncoding transcript |
|
|
R1800:Ncoa4-ps
|
UTSW |
12 |
119,225,506 (GRCm39) |
exon |
noncoding transcript |
|
|
R2280:Ncoa4-ps
|
UTSW |
12 |
119,226,573 (GRCm39) |
exon |
noncoding transcript |
|
|
R4827:Ncoa4-ps
|
UTSW |
12 |
119,225,529 (GRCm39) |
exon |
noncoding transcript |
|
|
R4922:Ncoa4-ps
|
UTSW |
12 |
119,226,252 (GRCm39) |
exon |
noncoding transcript |
|
|
R5183:Ncoa4-ps
|
UTSW |
12 |
119,225,023 (GRCm39) |
exon |
noncoding transcript |
|
|
R5562:Ncoa4-ps
|
UTSW |
12 |
119,225,957 (GRCm39) |
exon |
noncoding transcript |
|
|
R5752:Ncoa4-ps
|
UTSW |
12 |
119,226,349 (GRCm39) |
exon |
noncoding transcript |
|
|
R6033:Ncoa4-ps
|
UTSW |
12 |
119,225,475 (GRCm39) |
exon |
noncoding transcript |
|
|
R6033:Ncoa4-ps
|
UTSW |
12 |
119,225,475 (GRCm39) |
exon |
noncoding transcript |
|
|
R6084:Ncoa4-ps
|
UTSW |
12 |
119,225,386 (GRCm39) |
exon |
noncoding transcript |
|
|
R6151:Ncoa4-ps
|
UTSW |
12 |
119,224,841 (GRCm39) |
exon |
noncoding transcript |
|
|
X0024:Ncoa4-ps
|
UTSW |
12 |
119,225,419 (GRCm39) |
exon |
noncoding transcript |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTTCTCCCTGCCAGTGCAGAAC -3'
(R):5'- CATTAGCCAATAGAGCTGCTGAGCC -3'
Sequencing Primer
(F):5'- gtctcggtctattcctctactac -3'
(R):5'- TGCTGAGCCTGCTGCTG -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation