Incidental Mutation 'IGL00586:Gm5771'
ID6363
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5771
Ensembl Gene ENSMUSG00000058119
Gene Namepredicted gene 5771
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.084) question?
Stock #IGL00586
Quality Score
Status
Chromosome6
Chromosomal Location41392356-41397230 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 41396115 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Threonine at position 107 (I107T)
Ref Sequence ENSEMBL: ENSMUSP00000039684 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000049079]
Predicted Effect probably damaging
Transcript: ENSMUST00000049079
AA Change: I107T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000039684
Gene: ENSMUSG00000058119
AA Change: I107T

DomainStartEndE-ValueType
low complexity region 3 16 N/A INTRINSIC
Tryp_SPc 22 238 9.72e-105 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arl5b T C 2: 15,069,935 S76P probably benign Het
Asap3 A C 4: 136,206,568 D17A probably damaging Het
Casc1 A T 6: 145,191,576 F269I possibly damaging Het
Ccdc24 C T 4: 117,872,046 R78H probably damaging Het
Crp T C 1: 172,699,001 F218L probably benign Het
Dab2 T C 15: 6,429,825 L385P probably benign Het
Dip2c C A 13: 9,610,755 T855N probably damaging Het
Ep400 A G 5: 110,739,594 V541A probably damaging Het
Gbgt1 A T 2: 28,502,195 probably null Het
Gm6871 A T 7: 41,546,421 D297E possibly damaging Het
Gpr107 T A 2: 31,171,994 F145I probably benign Het
Itgb6 T G 2: 60,620,352 D581A probably benign Het
Lce1a1 C T 3: 92,647,163 M1I probably null Het
Lmbrd2 G A 15: 9,157,295 V207M probably damaging Het
Muc5b T A 7: 141,841,392 V45E unknown Het
Mybpc2 A G 7: 44,505,382 V977A probably damaging Het
Oas1c T C 5: 120,808,679 T29A probably benign Het
Pdzd2 G T 15: 12,365,767 probably null Het
Plk2 T C 13: 110,396,378 Y158H possibly damaging Het
Ptprq A G 10: 107,608,122 probably benign Het
Rnf17 C T 14: 56,421,082 T76I probably damaging Het
Serpinb1c T C 13: 32,883,975 K213E probably damaging Het
Sidt2 A G 9: 45,943,052 V624A possibly damaging Het
Sin3b T C 8: 72,757,000 V1005A probably benign Het
Ubr4 T C 4: 139,455,184 V358A possibly damaging Het
Wdr60 A T 12: 116,241,780 D396E probably benign Het
Zfp120 T C 2: 150,119,828 I67V possibly damaging Het
Zfp942 A T 17: 21,928,624 H341Q probably damaging Het
Other mutations in Gm5771
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00330:Gm5771 APN 6 41394773 missense probably damaging 1.00
IGL01103:Gm5771 APN 6 41397157 missense probably damaging 1.00
IGL01368:Gm5771 APN 6 41396686 missense possibly damaging 0.94
IGL01458:Gm5771 APN 6 41396687 missense probably benign 0.01
IGL03114:Gm5771 APN 6 41397078 missense probably damaging 1.00
R0167:Gm5771 UTSW 6 41396261 splice site probably benign
R1548:Gm5771 UTSW 6 41396011 missense probably damaging 1.00
R4584:Gm5771 UTSW 6 41396767 missense probably benign 0.35
R5622:Gm5771 UTSW 6 41396150 missense probably damaging 1.00
R5664:Gm5771 UTSW 6 41394671 missense probably benign 0.04
R6222:Gm5771 UTSW 6 41397166 missense probably damaging 0.98
R6325:Gm5771 UTSW 6 41396656 missense probably benign 0.00
Posted On2012-04-20