Incidental Mutation 'R0323:Tnrc6c'
| ID |
65032 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6c
|
| Ensembl Gene |
ENSMUSG00000025571 |
| Gene Name |
trinucleotide repeat containing 6C |
| Synonyms |
9930033H14Rik |
| MMRRC Submission |
038533-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0323 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
117545115-117654265 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 117630707 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 1023
(K1023E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000115221
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026658]
[ENSMUST00000106344]
[ENSMUST00000138299]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000026658
AA Change: K1183E
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000026658
Gene: ENSMUSG00000025571
AA Change: K1183E
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000106344
AA Change: K1183E
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000101951
Gene: ENSMUSG00000025571
AA Change: K1183E
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000138299
AA Change: K1023E
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000115221
Gene: ENSMUSG00000025571
AA Change: K1023E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
88 |
97 |
N/A |
INTRINSIC |
|
low complexity region
|
138 |
158 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
248 |
N/A |
INTRINSIC |
|
low complexity region
|
280 |
297 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
312 |
413 |
9.45e-5 |
PROSPERO |
|
low complexity region
|
434 |
454 |
N/A |
INTRINSIC |
|
low complexity region
|
461 |
472 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
639 |
742 |
9.45e-5 |
PROSPERO |
|
low complexity region
|
804 |
821 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
951 |
965 |
N/A |
INTRINSIC |
|
UBA
|
985 |
1022 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1036 |
1293 |
1.7e-53 |
PFAM |
|
low complexity region
|
1397 |
1406 |
N/A |
INTRINSIC |
|
PDB:3KTP|B
|
1422 |
1443 |
7e-7 |
PDB |
|
low complexity region
|
1507 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1531 |
1552 |
N/A |
INTRINSIC |
|
RRM
|
1557 |
1624 |
1.81e-2 |
SMART |
|
low complexity region
|
1645 |
1655 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140347
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141115
|
| Meta Mutation Damage Score |
0.1710 |
| Coding Region Coverage |
- 1x: 98.7%
- 3x: 97.5%
- 10x: 94.2%
- 20x: 86.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap allele exhibit complete neonatal lethality with cyanosis, respiratory distress and thickened mesenchyme in air sacs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
A |
T |
13: 77,446,674 (GRCm39) |
T816S |
possibly damaging |
Het |
| 4930527J03Rik |
ACCC |
ACC |
1: 178,276,503 (GRCm38) |
|
noncoding transcript |
Het |
| 4931429P17Rik |
A |
C |
13: 48,114,493 (GRCm39) |
|
noncoding transcript |
Het |
| Abca13 |
A |
C |
11: 9,244,701 (GRCm39) |
D2188A |
probably benign |
Het |
| Accsl |
T |
A |
2: 93,691,425 (GRCm39) |
Q351L |
probably benign |
Het |
| Acot6 |
A |
C |
12: 84,155,953 (GRCm39) |
E300D |
probably benign |
Het |
| Adgre1 |
T |
A |
17: 57,751,060 (GRCm39) |
I578N |
probably benign |
Het |
| Agbl4 |
T |
C |
4: 111,474,419 (GRCm39) |
S403P |
probably damaging |
Het |
| Agps |
T |
A |
2: 75,724,505 (GRCm39) |
Y506* |
probably null |
Het |
| Appl1 |
A |
T |
14: 26,664,695 (GRCm39) |
V446D |
possibly damaging |
Het |
| Arcn1 |
A |
T |
9: 44,670,356 (GRCm39) |
I90N |
probably damaging |
Het |
| Aspscr1 |
G |
A |
11: 120,569,246 (GRCm39) |
V15I |
probably damaging |
Het |
| Asxl2 |
A |
G |
12: 3,492,487 (GRCm39) |
Y24C |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,701,323 (GRCm39) |
F345S |
possibly damaging |
Het |
| Barx1 |
A |
G |
13: 48,819,430 (GRCm39) |
T243A |
probably benign |
Het |
| Bltp1 |
T |
A |
3: 36,997,331 (GRCm39) |
C1129* |
probably null |
Het |
| Bmp2k |
A |
G |
5: 97,235,682 (GRCm39) |
|
probably benign |
Het |
| Cacul1 |
A |
G |
19: 60,531,498 (GRCm39) |
I257T |
probably benign |
Het |
| Chml |
A |
T |
1: 175,514,650 (GRCm39) |
F424I |
probably benign |
Het |
| Clcn1 |
A |
T |
6: 42,287,074 (GRCm39) |
E710D |
probably damaging |
Het |
| Col1a2 |
G |
A |
6: 4,518,822 (GRCm39) |
|
probably benign |
Het |
| Cylc2 |
T |
A |
4: 51,228,477 (GRCm39) |
S183T |
unknown |
Het |
| Dhtkd1 |
T |
A |
2: 5,919,699 (GRCm39) |
M561L |
probably benign |
Het |
| Dnajc13 |
A |
G |
9: 104,034,091 (GRCm39) |
S2188P |
probably damaging |
Het |
| Dyrk1b |
C |
A |
7: 27,884,781 (GRCm39) |
Q399K |
probably benign |
Het |
| Erc1 |
T |
C |
6: 119,597,289 (GRCm39) |
K1003E |
probably damaging |
Het |
| Ezr |
G |
A |
17: 7,022,164 (GRCm39) |
Q105* |
probably null |
Het |
| Fam83d |
T |
A |
2: 158,627,467 (GRCm39) |
D385E |
probably benign |
Het |
| Fbn2 |
A |
G |
18: 58,178,389 (GRCm39) |
C1950R |
probably damaging |
Het |
| Fbxo32 |
A |
T |
15: 58,047,605 (GRCm39) |
I236N |
probably damaging |
Het |
| Fcgr1 |
T |
C |
3: 96,193,145 (GRCm39) |
E284G |
possibly damaging |
Het |
| Foxe3 |
T |
C |
4: 114,782,805 (GRCm39) |
N136D |
probably damaging |
Het |
| Fscn2 |
A |
T |
11: 120,258,837 (GRCm39) |
I461F |
probably damaging |
Het |
| Fsip2 |
T |
C |
2: 82,816,240 (GRCm39) |
I3991T |
probably benign |
Het |
| Galnt15 |
A |
T |
14: 31,770,042 (GRCm39) |
H249L |
probably damaging |
Het |
| Gm10803 |
T |
A |
2: 93,394,415 (GRCm39) |
Y62* |
probably null |
Het |
| Gm20730 |
G |
A |
6: 43,058,449 (GRCm39) |
|
probably null |
Het |
| Gm4841 |
A |
G |
18: 60,403,718 (GRCm39) |
L125S |
possibly damaging |
Het |
| Gmpr2 |
A |
G |
14: 55,910,203 (GRCm39) |
D11G |
probably damaging |
Het |
| Gucy1b1 |
T |
A |
3: 81,945,463 (GRCm39) |
|
probably null |
Het |
| Hhla1 |
C |
A |
15: 65,820,352 (GRCm39) |
V133F |
probably benign |
Het |
| Hscb |
T |
C |
5: 110,982,556 (GRCm39) |
E177G |
possibly damaging |
Het |
| Hyal4 |
A |
T |
6: 24,756,193 (GRCm39) |
N137I |
probably benign |
Het |
| Lcp2 |
A |
G |
11: 34,004,322 (GRCm39) |
D53G |
probably damaging |
Het |
| Ldb3 |
G |
A |
14: 34,266,002 (GRCm39) |
T531I |
probably damaging |
Het |
| Llgl2 |
A |
G |
11: 115,741,546 (GRCm39) |
K559E |
probably damaging |
Het |
| Loxhd1 |
A |
G |
18: 77,456,833 (GRCm39) |
I499V |
probably benign |
Het |
| Lrp2 |
T |
C |
2: 69,299,983 (GRCm39) |
Y3023C |
probably damaging |
Het |
| Lrrc59 |
A |
C |
11: 94,534,248 (GRCm39) |
T269P |
probably damaging |
Het |
| Lrriq1 |
A |
T |
10: 103,057,150 (GRCm39) |
C217S |
possibly damaging |
Het |
| Mmrn2 |
A |
T |
14: 34,119,991 (GRCm39) |
Q287L |
probably damaging |
Het |
| Mplkip |
A |
G |
13: 17,871,565 (GRCm39) |
I159V |
possibly damaging |
Het |
| Napg |
C |
T |
18: 63,120,034 (GRCm39) |
R149C |
probably damaging |
Het |
| Nrxn1 |
A |
C |
17: 91,008,170 (GRCm39) |
|
probably null |
Het |
| Or10ag60 |
G |
A |
2: 87,437,841 (GRCm39) |
M36I |
probably benign |
Het |
| Or1e17 |
A |
T |
11: 73,831,773 (GRCm39) |
I234F |
probably benign |
Het |
| Or6c70 |
T |
A |
10: 129,709,936 (GRCm39) |
Q230L |
probably damaging |
Het |
| Or6d15 |
A |
T |
6: 116,559,562 (GRCm39) |
V115E |
probably damaging |
Het |
| Or6n2 |
A |
G |
1: 173,896,893 (GRCm39) |
T10A |
probably benign |
Het |
| Orc4 |
A |
T |
2: 48,827,479 (GRCm39) |
V38E |
possibly damaging |
Het |
| Palm3 |
T |
A |
8: 84,755,349 (GRCm39) |
V287D |
probably damaging |
Het |
| Pde11a |
C |
T |
2: 75,877,118 (GRCm39) |
|
probably null |
Het |
| Pdss2 |
T |
A |
10: 43,248,172 (GRCm39) |
H225Q |
probably benign |
Het |
| Pkhd1 |
A |
T |
1: 20,345,762 (GRCm39) |
D2755E |
probably benign |
Het |
| Pla2g5 |
C |
T |
4: 138,527,967 (GRCm39) |
D100N |
probably benign |
Het |
| Polrmt |
T |
C |
10: 79,577,832 (GRCm39) |
T287A |
probably benign |
Het |
| Ppfia2 |
A |
G |
10: 106,732,281 (GRCm39) |
I943V |
possibly damaging |
Het |
| Pth2r |
A |
C |
1: 65,427,775 (GRCm39) |
I483L |
probably benign |
Het |
| Qrsl1 |
A |
G |
10: 43,772,003 (GRCm39) |
|
probably null |
Het |
| Ralgapa1 |
A |
T |
12: 55,724,023 (GRCm39) |
I1548N |
probably damaging |
Het |
| Scn9a |
T |
C |
2: 66,398,475 (GRCm39) |
E45G |
probably damaging |
Het |
| Sf3b1 |
T |
C |
1: 55,058,416 (GRCm39) |
I58V |
probably damaging |
Het |
| Sh3d19 |
T |
A |
3: 86,033,978 (GRCm39) |
M777K |
probably benign |
Het |
| Shc1 |
T |
C |
3: 89,331,020 (GRCm39) |
L106P |
probably damaging |
Het |
| Skint5 |
T |
C |
4: 113,794,818 (GRCm39) |
H255R |
probably benign |
Het |
| Slc28a3 |
C |
A |
13: 58,711,866 (GRCm39) |
G487* |
probably null |
Het |
| Slc49a4 |
ACC |
AC |
16: 35,539,730 (GRCm39) |
|
probably null |
Het |
| Slfn4 |
A |
T |
11: 83,077,777 (GRCm39) |
R188S |
probably damaging |
Het |
| Slitrk5 |
A |
G |
14: 111,919,055 (GRCm39) |
D893G |
probably damaging |
Het |
| Spta1 |
A |
G |
1: 174,046,017 (GRCm39) |
T1594A |
probably damaging |
Het |
| Srarp |
G |
A |
4: 141,160,690 (GRCm39) |
Q48* |
probably null |
Het |
| Srf |
T |
C |
17: 46,860,415 (GRCm39) |
T456A |
possibly damaging |
Het |
| Stx2 |
C |
T |
5: 129,065,967 (GRCm39) |
V230I |
probably benign |
Het |
| Tenm4 |
C |
A |
7: 96,344,157 (GRCm39) |
P250Q |
possibly damaging |
Het |
| Trpc6 |
A |
T |
9: 8,610,276 (GRCm39) |
H248L |
probably damaging |
Het |
| Trpc6 |
A |
G |
9: 8,643,537 (GRCm39) |
K441E |
probably damaging |
Het |
| Uty |
T |
A |
Y: 1,169,979 (GRCm39) |
I326F |
probably damaging |
Het |
| Vmn1r63 |
A |
G |
7: 5,806,335 (GRCm39) |
V99A |
probably benign |
Het |
| Wnt11 |
A |
G |
7: 98,496,590 (GRCm39) |
K177E |
probably damaging |
Het |
| Wwc1 |
T |
A |
11: 35,743,175 (GRCm39) |
E882V |
probably damaging |
Het |
| Zfhx2 |
C |
A |
14: 55,303,436 (GRCm39) |
S1516I |
possibly damaging |
Het |
| Zmpste24 |
A |
G |
4: 120,940,050 (GRCm39) |
Y199H |
probably damaging |
Het |
|
| Other mutations in Tnrc6c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00839:Tnrc6c
|
APN |
11 |
117,605,011 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01013:Tnrc6c
|
APN |
11 |
117,612,855 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01092:Tnrc6c
|
APN |
11 |
117,612,811 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01383:Tnrc6c
|
APN |
11 |
117,605,083 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01395:Tnrc6c
|
APN |
11 |
117,613,939 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01726:Tnrc6c
|
APN |
11 |
117,640,161 (GRCm39) |
splice site |
probably benign |
|
|
IGL01869:Tnrc6c
|
APN |
11 |
117,646,274 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL02108:Tnrc6c
|
APN |
11 |
117,612,025 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02457:Tnrc6c
|
APN |
11 |
117,613,803 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02612:Tnrc6c
|
APN |
11 |
117,633,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02748:Tnrc6c
|
APN |
11 |
117,622,996 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03160:Tnrc6c
|
APN |
11 |
117,640,651 (GRCm39) |
splice site |
probably benign |
|
|
rodion
|
UTSW |
11 |
117,629,176 (GRCm39) |
critical splice donor site |
probably null |
|
|
F5770:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
K3955:Tnrc6c
|
UTSW |
11 |
117,651,564 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0015:Tnrc6c
|
UTSW |
11 |
117,612,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0143:Tnrc6c
|
UTSW |
11 |
117,643,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0277:Tnrc6c
|
UTSW |
11 |
117,630,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0464:Tnrc6c
|
UTSW |
11 |
117,651,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0699:Tnrc6c
|
UTSW |
11 |
117,613,447 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1015:Tnrc6c
|
UTSW |
11 |
117,612,748 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1201:Tnrc6c
|
UTSW |
11 |
117,612,500 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1297:Tnrc6c
|
UTSW |
11 |
117,624,529 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1560:Tnrc6c
|
UTSW |
11 |
117,650,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1596:Tnrc6c
|
UTSW |
11 |
117,648,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnrc6c
|
UTSW |
11 |
117,651,556 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1892:Tnrc6c
|
UTSW |
11 |
117,605,188 (GRCm39) |
missense |
probably benign |
|
|
R1901:Tnrc6c
|
UTSW |
11 |
117,613,831 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1935:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1936:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1937:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1940:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R3622:Tnrc6c
|
UTSW |
11 |
117,640,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3711:Tnrc6c
|
UTSW |
11 |
117,613,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3725:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3775:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3776:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3836:Tnrc6c
|
UTSW |
11 |
117,614,055 (GRCm39) |
missense |
probably benign |
0.20 |
|
R3844:Tnrc6c
|
UTSW |
11 |
117,646,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3852:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3928:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3929:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3937:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3943:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4501:Tnrc6c
|
UTSW |
11 |
117,613,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Tnrc6c
|
UTSW |
11 |
117,633,784 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4511:Tnrc6c
|
UTSW |
11 |
117,633,784 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4654:Tnrc6c
|
UTSW |
11 |
117,611,797 (GRCm39) |
missense |
probably benign |
|
|
R4765:Tnrc6c
|
UTSW |
11 |
117,633,753 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4824:Tnrc6c
|
UTSW |
11 |
117,613,731 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5004:Tnrc6c
|
UTSW |
11 |
117,611,872 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5094:Tnrc6c
|
UTSW |
11 |
117,611,872 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5130:Tnrc6c
|
UTSW |
11 |
117,629,176 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5234:Tnrc6c
|
UTSW |
11 |
117,651,555 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5235:Tnrc6c
|
UTSW |
11 |
117,651,555 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5345:Tnrc6c
|
UTSW |
11 |
117,614,113 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5359:Tnrc6c
|
UTSW |
11 |
117,649,731 (GRCm39) |
splice site |
silent |
|
|
R5428:Tnrc6c
|
UTSW |
11 |
117,591,588 (GRCm39) |
start codon destroyed |
probably null |
|
|
R5548:Tnrc6c
|
UTSW |
11 |
117,651,669 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5587:Tnrc6c
|
UTSW |
11 |
117,640,097 (GRCm39) |
nonsense |
probably null |
|
|
R5875:Tnrc6c
|
UTSW |
11 |
117,650,534 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5947:Tnrc6c
|
UTSW |
11 |
117,613,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6135:Tnrc6c
|
UTSW |
11 |
117,626,831 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6354:Tnrc6c
|
UTSW |
11 |
117,640,440 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6389:Tnrc6c
|
UTSW |
11 |
117,613,567 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7027:Tnrc6c
|
UTSW |
11 |
117,624,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7048:Tnrc6c
|
UTSW |
11 |
117,612,800 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7098:Tnrc6c
|
UTSW |
11 |
117,604,952 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7315:Tnrc6c
|
UTSW |
11 |
117,614,354 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7378:Tnrc6c
|
UTSW |
11 |
117,632,606 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7386:Tnrc6c
|
UTSW |
11 |
117,612,780 (GRCm39) |
missense |
probably benign |
|
|
R7515:Tnrc6c
|
UTSW |
11 |
117,632,507 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7665:Tnrc6c
|
UTSW |
11 |
117,611,777 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7755:Tnrc6c
|
UTSW |
11 |
117,648,912 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8679:Tnrc6c
|
UTSW |
11 |
117,604,961 (GRCm39) |
missense |
probably benign |
|
|
R8824:Tnrc6c
|
UTSW |
11 |
117,630,680 (GRCm39) |
splice site |
probably benign |
|
|
R8971:Tnrc6c
|
UTSW |
11 |
117,640,089 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9261:Tnrc6c
|
UTSW |
11 |
117,605,105 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9283:Tnrc6c
|
UTSW |
11 |
117,591,630 (GRCm39) |
missense |
unknown |
|
|
R9342:Tnrc6c
|
UTSW |
11 |
117,630,720 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9633:Tnrc6c
|
UTSW |
11 |
117,638,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Tnrc6c
|
UTSW |
11 |
117,623,136 (GRCm39) |
missense |
probably benign |
|
|
V7580:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7581:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7582:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7583:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnrc6c
|
UTSW |
11 |
117,623,003 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
|
| Posted On |
2013-08-08 |
Incidental Mutation