Incidental Mutation 'R0277:Myo9b'
| ID |
65302 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo9b
|
| Ensembl Gene |
ENSMUSG00000004677 |
| Gene Name |
myosin IXb |
| Synonyms |
|
| MMRRC Submission |
038499-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.852)
|
| Stock # |
R0277 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
71725358-71813357 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to C
at 71808596 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000148316
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071935]
[ENSMUST00000168839]
[ENSMUST00000170242]
[ENSMUST00000212935]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071935
|
| SMART Domains |
Protein: ENSMUSP00000071827
Gene: ENSMUSG00000004677
| Domain | Start | End | E-Value | Type |
|---|
|
RA
|
15 |
114 |
3.7e-30 |
SMART |
|
MYSc
|
140 |
954 |
N/A |
SMART |
|
IQ
|
955 |
977 |
1.2e-3 |
SMART |
|
IQ
|
978 |
1000 |
1.6e-5 |
SMART |
|
IQ
|
1001 |
1022 |
4.3e-5 |
SMART |
|
IQ
|
1023 |
1045 |
8.4e-5 |
SMART |
|
low complexity region
|
1050 |
1064 |
N/A |
INTRINSIC |
|
low complexity region
|
1127 |
1145 |
N/A |
INTRINSIC |
|
low complexity region
|
1211 |
1222 |
N/A |
INTRINSIC |
|
low complexity region
|
1232 |
1246 |
N/A |
INTRINSIC |
|
Blast:MYSc
|
1247 |
1323 |
3e-19 |
BLAST |
|
low complexity region
|
1348 |
1359 |
N/A |
INTRINSIC |
|
coiled coil region
|
1563 |
1590 |
N/A |
INTRINSIC |
|
C1
|
1591 |
1639 |
1.7e-14 |
SMART |
|
RhoGAP
|
1668 |
1843 |
4.7e-71 |
SMART |
|
coiled coil region
|
1901 |
1925 |
N/A |
INTRINSIC |
|
low complexity region
|
1940 |
1952 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168839
|
| SMART Domains |
Protein: ENSMUSP00000131635
Gene: ENSMUSG00000004677
| Domain | Start | End | E-Value | Type |
|---|
|
RA
|
15 |
114 |
5.79e-28 |
SMART |
|
MYSc
|
140 |
954 |
N/A |
SMART |
|
IQ
|
955 |
977 |
2.46e-1 |
SMART |
|
IQ
|
978 |
1000 |
3.35e-3 |
SMART |
|
IQ
|
1001 |
1022 |
8.84e-3 |
SMART |
|
IQ
|
1023 |
1045 |
1.77e-2 |
SMART |
|
low complexity region
|
1050 |
1064 |
N/A |
INTRINSIC |
|
low complexity region
|
1127 |
1145 |
N/A |
INTRINSIC |
|
low complexity region
|
1211 |
1222 |
N/A |
INTRINSIC |
|
low complexity region
|
1234 |
1257 |
N/A |
INTRINSIC |
|
Blast:MYSc
|
1258 |
1334 |
3e-19 |
BLAST |
|
low complexity region
|
1361 |
1372 |
N/A |
INTRINSIC |
|
low complexity region
|
1581 |
1601 |
N/A |
INTRINSIC |
|
C1
|
1605 |
1653 |
3.58e-12 |
SMART |
|
RhoGAP
|
1682 |
1857 |
7.78e-69 |
SMART |
|
coiled coil region
|
1915 |
1939 |
N/A |
INTRINSIC |
|
low complexity region
|
1954 |
1966 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170242
|
| SMART Domains |
Protein: ENSMUSP00000129220
Gene: ENSMUSG00000004677
| Domain | Start | End | E-Value | Type |
|---|
|
RA
|
15 |
114 |
5.79e-28 |
SMART |
|
MYSc
|
140 |
954 |
N/A |
SMART |
|
IQ
|
955 |
977 |
2.46e-1 |
SMART |
|
IQ
|
978 |
1000 |
3.35e-3 |
SMART |
|
IQ
|
1001 |
1022 |
8.84e-3 |
SMART |
|
IQ
|
1023 |
1045 |
1.77e-2 |
SMART |
|
low complexity region
|
1050 |
1064 |
N/A |
INTRINSIC |
|
low complexity region
|
1127 |
1145 |
N/A |
INTRINSIC |
|
low complexity region
|
1211 |
1222 |
N/A |
INTRINSIC |
|
low complexity region
|
1234 |
1257 |
N/A |
INTRINSIC |
|
Blast:MYSc
|
1258 |
1334 |
3e-19 |
BLAST |
|
low complexity region
|
1361 |
1372 |
N/A |
INTRINSIC |
|
low complexity region
|
1581 |
1601 |
N/A |
INTRINSIC |
|
C1
|
1605 |
1653 |
3.58e-12 |
SMART |
|
RhoGAP
|
1682 |
1857 |
7.78e-69 |
SMART |
|
coiled coil region
|
1931 |
1955 |
N/A |
INTRINSIC |
|
low complexity region
|
1970 |
1982 |
N/A |
INTRINSIC |
|
low complexity region
|
1992 |
2003 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212412
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212935
|
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.7%
- 10x: 95.0%
- 20x: 89.3%
|
| Validation Efficiency |
99% (111/112) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
PHENOTYPE: Homozygous null mutants breed normal, but shows defect in macrophage motility and chemotaxis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 109 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930533L02Rik |
A |
G |
7: 124,917,815 (GRCm39) |
K69R |
unknown |
Het |
| Abca13 |
A |
C |
11: 9,244,701 (GRCm39) |
D2188A |
probably benign |
Het |
| Acad11 |
T |
C |
9: 104,001,224 (GRCm39) |
M708T |
probably damaging |
Het |
| Adam7 |
T |
C |
14: 68,748,306 (GRCm39) |
|
probably null |
Het |
| Adgre1 |
T |
A |
17: 57,751,060 (GRCm39) |
I578N |
probably benign |
Het |
| Agbl4 |
T |
C |
4: 111,474,419 (GRCm39) |
S403P |
probably damaging |
Het |
| Ak3 |
A |
G |
19: 29,025,192 (GRCm39) |
M13T |
possibly damaging |
Het |
| Ap2s1 |
T |
C |
7: 16,481,305 (GRCm39) |
|
probably benign |
Het |
| Arhgef1 |
A |
T |
7: 24,623,224 (GRCm39) |
|
probably benign |
Het |
| Arsk |
T |
C |
13: 76,223,051 (GRCm39) |
N182S |
probably benign |
Het |
| Aspscr1 |
G |
A |
11: 120,569,246 (GRCm39) |
V15I |
probably damaging |
Het |
| Asxl2 |
A |
G |
12: 3,492,487 (GRCm39) |
Y24C |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,701,323 (GRCm39) |
F345S |
possibly damaging |
Het |
| Atp8b3 |
T |
C |
10: 80,362,743 (GRCm39) |
K672E |
probably benign |
Het |
| Bltp1 |
T |
A |
3: 36,997,331 (GRCm39) |
C1129* |
probably null |
Het |
| Bmp2k |
A |
G |
5: 97,235,682 (GRCm39) |
|
probably benign |
Het |
| Casp6 |
T |
A |
3: 129,704,172 (GRCm39) |
V86E |
probably benign |
Het |
| Cdca5 |
A |
G |
19: 6,140,742 (GRCm39) |
E260G |
unknown |
Het |
| Cpb2 |
T |
A |
14: 75,502,898 (GRCm39) |
V159D |
probably damaging |
Het |
| Cylc2 |
T |
A |
4: 51,228,477 (GRCm39) |
S183T |
unknown |
Het |
| Dhtkd1 |
T |
A |
2: 5,919,699 (GRCm39) |
M561L |
probably benign |
Het |
| Dync2h1 |
T |
C |
9: 7,129,046 (GRCm39) |
D1823G |
probably benign |
Het |
| Efcab5 |
G |
A |
11: 77,031,749 (GRCm39) |
R42W |
probably damaging |
Het |
| Erc1 |
T |
C |
6: 119,597,289 (GRCm39) |
K1003E |
probably damaging |
Het |
| Ezr |
G |
A |
17: 7,022,164 (GRCm39) |
Q105* |
probably null |
Het |
| Fam83d |
T |
A |
2: 158,627,467 (GRCm39) |
D385E |
probably benign |
Het |
| Fbn2 |
A |
G |
18: 58,178,389 (GRCm39) |
C1950R |
probably damaging |
Het |
| Fbxo32 |
A |
T |
15: 58,047,605 (GRCm39) |
I236N |
probably damaging |
Het |
| Fcgbp |
G |
T |
7: 27,784,918 (GRCm39) |
|
probably null |
Het |
| Foxe3 |
T |
C |
4: 114,782,805 (GRCm39) |
N136D |
probably damaging |
Het |
| Fscn2 |
A |
T |
11: 120,258,837 (GRCm39) |
I461F |
probably damaging |
Het |
| Gldc |
A |
G |
19: 30,093,851 (GRCm39) |
I722T |
possibly damaging |
Het |
| Gm10717 |
T |
G |
9: 3,025,619 (GRCm39) |
V68G |
possibly damaging |
Het |
| Gm4841 |
A |
G |
18: 60,403,718 (GRCm39) |
L125S |
possibly damaging |
Het |
| Gnl3 |
A |
C |
14: 30,735,384 (GRCm39) |
|
probably null |
Het |
| Gsto1 |
A |
T |
19: 47,846,416 (GRCm39) |
I88F |
probably damaging |
Het |
| Gucy1b1 |
T |
A |
3: 81,945,463 (GRCm39) |
|
probably null |
Het |
| Hhla1 |
C |
A |
15: 65,820,352 (GRCm39) |
V133F |
probably benign |
Het |
| Hipk3 |
T |
A |
2: 104,271,593 (GRCm39) |
L446F |
probably damaging |
Het |
| Hscb |
T |
C |
5: 110,982,556 (GRCm39) |
E177G |
possibly damaging |
Het |
| Hsd17b6 |
T |
C |
10: 127,827,274 (GRCm39) |
D266G |
probably benign |
Het |
| Ipo4 |
T |
C |
14: 55,869,572 (GRCm39) |
S363G |
probably benign |
Het |
| Kcnip3 |
A |
G |
2: 127,301,899 (GRCm39) |
|
probably benign |
Het |
| Klhl41 |
A |
G |
2: 69,501,640 (GRCm39) |
Y367C |
probably damaging |
Het |
| Klk1b4 |
C |
G |
7: 43,861,053 (GRCm39) |
P232R |
possibly damaging |
Het |
| Lcp2 |
A |
G |
11: 34,004,322 (GRCm39) |
D53G |
probably damaging |
Het |
| Llgl2 |
A |
G |
11: 115,741,546 (GRCm39) |
K559E |
probably damaging |
Het |
| Lrrc59 |
A |
C |
11: 94,534,248 (GRCm39) |
T269P |
probably damaging |
Het |
| Mark1 |
A |
G |
1: 184,677,149 (GRCm39) |
S34P |
possibly damaging |
Het |
| Megf11 |
G |
A |
9: 64,598,632 (GRCm39) |
|
probably null |
Het |
| Mplkip |
A |
G |
13: 17,871,565 (GRCm39) |
I159V |
possibly damaging |
Het |
| Muc4 |
C |
A |
16: 32,755,690 (GRCm38) |
|
probably benign |
Het |
| Myo18b |
A |
G |
5: 112,841,213 (GRCm39) |
|
probably benign |
Het |
| Napg |
C |
T |
18: 63,120,034 (GRCm39) |
R149C |
probably damaging |
Het |
| Ndrg3 |
A |
G |
2: 156,776,855 (GRCm39) |
|
probably benign |
Het |
| Nfe2l3 |
T |
A |
6: 51,434,448 (GRCm39) |
M336K |
probably benign |
Het |
| Nrxn1 |
A |
C |
17: 91,008,170 (GRCm39) |
|
probably null |
Het |
| Nsun3 |
A |
T |
16: 62,597,007 (GRCm39) |
|
probably benign |
Het |
| Nuak1 |
T |
C |
10: 84,210,315 (GRCm39) |
E591G |
probably benign |
Het |
| Or10g1b |
T |
C |
14: 52,627,846 (GRCm39) |
Y128C |
probably damaging |
Het |
| Or10s1 |
G |
A |
9: 39,986,010 (GRCm39) |
V140I |
probably benign |
Het |
| Or1e17 |
A |
T |
11: 73,831,773 (GRCm39) |
I234F |
probably benign |
Het |
| Or4k2 |
T |
C |
14: 50,423,789 (GRCm39) |
N296S |
probably null |
Het |
| Or6c70 |
T |
A |
10: 129,709,936 (GRCm39) |
Q230L |
probably damaging |
Het |
| Or6d15 |
A |
T |
6: 116,559,562 (GRCm39) |
V115E |
probably damaging |
Het |
| Or6z6 |
T |
A |
7: 6,491,433 (GRCm39) |
M147L |
probably benign |
Het |
| Orc4 |
A |
T |
2: 48,827,479 (GRCm39) |
V38E |
possibly damaging |
Het |
| Ovgp1 |
T |
C |
3: 105,887,208 (GRCm39) |
|
probably benign |
Het |
| Palm3 |
T |
A |
8: 84,755,349 (GRCm39) |
V287D |
probably damaging |
Het |
| Pde4dip |
T |
A |
3: 97,751,028 (GRCm39) |
H62L |
probably benign |
Het |
| Pdk4 |
G |
T |
6: 5,491,620 (GRCm39) |
P100Q |
probably damaging |
Het |
| Pdss2 |
T |
A |
10: 43,248,172 (GRCm39) |
H225Q |
probably benign |
Het |
| Pkhd1 |
A |
T |
1: 20,345,762 (GRCm39) |
D2755E |
probably benign |
Het |
| Prune2 |
A |
T |
19: 17,098,753 (GRCm39) |
D1419V |
probably damaging |
Het |
| Pth2r |
A |
C |
1: 65,427,775 (GRCm39) |
I483L |
probably benign |
Het |
| Qrsl1 |
A |
G |
10: 43,772,003 (GRCm39) |
|
probably null |
Het |
| Rab11fip4 |
A |
G |
11: 79,577,455 (GRCm39) |
H403R |
possibly damaging |
Het |
| Ralgapa1 |
A |
T |
12: 55,724,023 (GRCm39) |
I1548N |
probably damaging |
Het |
| Ric8a |
T |
G |
7: 140,437,813 (GRCm39) |
|
probably benign |
Het |
| Rsbn1 |
T |
C |
3: 103,821,897 (GRCm39) |
F44S |
possibly damaging |
Het |
| Serpinc1 |
T |
A |
1: 160,817,272 (GRCm39) |
M1K |
probably null |
Het |
| Sf3b1 |
T |
C |
1: 55,058,416 (GRCm39) |
I58V |
probably damaging |
Het |
| Sh3d19 |
T |
A |
3: 86,033,978 (GRCm39) |
M777K |
probably benign |
Het |
| Sipa1 |
A |
T |
19: 5,704,093 (GRCm39) |
M743K |
probably benign |
Het |
| Skint5 |
T |
C |
4: 113,794,818 (GRCm39) |
H255R |
probably benign |
Het |
| Slco6b1 |
A |
T |
1: 96,916,398 (GRCm39) |
|
noncoding transcript |
Het |
| Slfn4 |
A |
T |
11: 83,077,777 (GRCm39) |
R188S |
probably damaging |
Het |
| Sort1 |
T |
C |
3: 108,231,908 (GRCm39) |
|
probably benign |
Het |
| Spg21 |
A |
T |
9: 65,372,629 (GRCm39) |
K20N |
possibly damaging |
Het |
| Sptbn2 |
A |
T |
19: 4,795,173 (GRCm39) |
I1544F |
probably benign |
Het |
| Srf |
T |
C |
17: 46,860,415 (GRCm39) |
T456A |
possibly damaging |
Het |
| Ssbp2 |
T |
A |
13: 91,712,715 (GRCm39) |
|
probably benign |
Het |
| Stx2 |
C |
T |
5: 129,065,967 (GRCm39) |
V230I |
probably benign |
Het |
| Sv2b |
A |
T |
7: 74,856,187 (GRCm39) |
D34E |
possibly damaging |
Het |
| Synpo2l |
A |
G |
14: 20,711,856 (GRCm39) |
S255P |
probably damaging |
Het |
| Tbx15 |
C |
T |
3: 99,259,707 (GRCm39) |
P526L |
probably damaging |
Het |
| Tenm4 |
C |
A |
7: 96,344,157 (GRCm39) |
P250Q |
possibly damaging |
Het |
| Tgm1 |
C |
A |
14: 55,948,384 (GRCm39) |
|
probably benign |
Het |
| Tgm1 |
T |
C |
14: 55,950,109 (GRCm39) |
|
probably benign |
Het |
| Thsd7b |
A |
G |
1: 130,123,000 (GRCm39) |
I1540V |
probably benign |
Het |
| Tnrc6c |
A |
G |
11: 117,630,707 (GRCm39) |
K1023E |
probably damaging |
Het |
| Ube2l6 |
A |
T |
2: 84,636,771 (GRCm39) |
|
probably null |
Het |
| Uty |
T |
A |
Y: 1,169,979 (GRCm39) |
I326F |
probably damaging |
Het |
| Wdfy4 |
T |
C |
14: 32,805,742 (GRCm39) |
D1735G |
possibly damaging |
Het |
| Wnt11 |
A |
G |
7: 98,496,590 (GRCm39) |
K177E |
probably damaging |
Het |
| Wnt5a |
A |
T |
14: 28,235,225 (GRCm39) |
M70L |
possibly damaging |
Het |
| Wwc1 |
T |
A |
11: 35,743,175 (GRCm39) |
E882V |
probably damaging |
Het |
| Zfp455 |
G |
T |
13: 67,346,728 (GRCm39) |
|
probably null |
Het |
| Zmpste24 |
A |
G |
4: 120,940,050 (GRCm39) |
Y199H |
probably damaging |
Het |
|
| Other mutations in Myo9b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00163:Myo9b
|
APN |
8 |
71,801,379 (GRCm39) |
missense |
probably benign |
|
|
IGL01020:Myo9b
|
APN |
8 |
71,804,644 (GRCm39) |
missense |
probably benign |
|
|
IGL01479:Myo9b
|
APN |
8 |
71,811,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01704:Myo9b
|
APN |
8 |
71,812,286 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01761:Myo9b
|
APN |
8 |
71,801,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01766:Myo9b
|
APN |
8 |
71,743,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01834:Myo9b
|
APN |
8 |
71,807,901 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01834:Myo9b
|
APN |
8 |
71,808,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01838:Myo9b
|
APN |
8 |
71,787,034 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02318:Myo9b
|
APN |
8 |
71,806,768 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02333:Myo9b
|
APN |
8 |
71,811,637 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL02340:Myo9b
|
APN |
8 |
71,743,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02514:Myo9b
|
APN |
8 |
71,743,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02593:Myo9b
|
APN |
8 |
71,743,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03075:Myo9b
|
APN |
8 |
71,807,171 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03332:Myo9b
|
APN |
8 |
71,801,418 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
avantgarde
|
UTSW |
8 |
71,796,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Freaky
|
UTSW |
8 |
71,743,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
iconoclastic
|
UTSW |
8 |
71,743,119 (GRCm39) |
missense |
probably benign |
0.37 |
|
unconventional
|
UTSW |
8 |
71,801,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4418001:Myo9b
|
UTSW |
8 |
71,775,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4651001:Myo9b
|
UTSW |
8 |
71,795,456 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R0023:Myo9b
|
UTSW |
8 |
71,786,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0103:Myo9b
|
UTSW |
8 |
71,776,493 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Myo9b
|
UTSW |
8 |
71,776,493 (GRCm39) |
splice site |
probably benign |
|
|
R0144:Myo9b
|
UTSW |
8 |
71,798,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0207:Myo9b
|
UTSW |
8 |
71,807,869 (GRCm39) |
splice site |
probably benign |
|
|
R0226:Myo9b
|
UTSW |
8 |
71,806,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0227:Myo9b
|
UTSW |
8 |
71,796,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0244:Myo9b
|
UTSW |
8 |
71,774,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0362:Myo9b
|
UTSW |
8 |
71,800,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0689:Myo9b
|
UTSW |
8 |
71,783,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0844:Myo9b
|
UTSW |
8 |
71,743,119 (GRCm39) |
missense |
probably benign |
0.37 |
|
R1051:Myo9b
|
UTSW |
8 |
71,808,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Myo9b
|
UTSW |
8 |
71,743,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Myo9b
|
UTSW |
8 |
71,743,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1526:Myo9b
|
UTSW |
8 |
71,808,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myo9b
|
UTSW |
8 |
71,743,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Myo9b
|
UTSW |
8 |
71,767,836 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1645:Myo9b
|
UTSW |
8 |
71,775,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1745:Myo9b
|
UTSW |
8 |
71,806,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1820:Myo9b
|
UTSW |
8 |
71,786,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2037:Myo9b
|
UTSW |
8 |
71,743,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2050:Myo9b
|
UTSW |
8 |
71,743,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2056:Myo9b
|
UTSW |
8 |
71,812,334 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R2129:Myo9b
|
UTSW |
8 |
71,786,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2423:Myo9b
|
UTSW |
8 |
71,780,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2869:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2869:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2871:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2871:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2872:Myo9b
|
UTSW |
8 |
71,743,610 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2872:Myo9b
|
UTSW |
8 |
71,743,610 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2873:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2874:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2920:Myo9b
|
UTSW |
8 |
71,778,501 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2926:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2939:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2940:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3033:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3040:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3689:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3691:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3735:Myo9b
|
UTSW |
8 |
71,801,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4194:Myo9b
|
UTSW |
8 |
71,812,268 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4258:Myo9b
|
UTSW |
8 |
71,808,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4457:Myo9b
|
UTSW |
8 |
71,743,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4478:Myo9b
|
UTSW |
8 |
71,743,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4496:Myo9b
|
UTSW |
8 |
71,786,981 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4544:Myo9b
|
UTSW |
8 |
71,780,585 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4580:Myo9b
|
UTSW |
8 |
71,767,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4736:Myo9b
|
UTSW |
8 |
71,809,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5068:Myo9b
|
UTSW |
8 |
71,801,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5124:Myo9b
|
UTSW |
8 |
71,808,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5194:Myo9b
|
UTSW |
8 |
71,801,733 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5296:Myo9b
|
UTSW |
8 |
71,786,032 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5528:Myo9b
|
UTSW |
8 |
71,775,918 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5664:Myo9b
|
UTSW |
8 |
71,812,526 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5677:Myo9b
|
UTSW |
8 |
71,796,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5680:Myo9b
|
UTSW |
8 |
71,743,016 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5982:Myo9b
|
UTSW |
8 |
71,801,040 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6344:Myo9b
|
UTSW |
8 |
71,780,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6352:Myo9b
|
UTSW |
8 |
71,801,055 (GRCm39) |
missense |
probably benign |
|
|
R6352:Myo9b
|
UTSW |
8 |
71,801,054 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6411:Myo9b
|
UTSW |
8 |
71,775,599 (GRCm39) |
nonsense |
probably null |
|
|
R6425:Myo9b
|
UTSW |
8 |
71,786,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6505:Myo9b
|
UTSW |
8 |
71,808,501 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6743:Myo9b
|
UTSW |
8 |
71,804,803 (GRCm39) |
splice site |
probably null |
|
|
R6811:Myo9b
|
UTSW |
8 |
71,809,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6813:Myo9b
|
UTSW |
8 |
71,775,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6954:Myo9b
|
UTSW |
8 |
71,743,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7124:Myo9b
|
UTSW |
8 |
71,786,345 (GRCm39) |
nonsense |
probably null |
|
|
R7255:Myo9b
|
UTSW |
8 |
71,743,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7293:Myo9b
|
UTSW |
8 |
71,778,549 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7342:Myo9b
|
UTSW |
8 |
71,808,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7451:Myo9b
|
UTSW |
8 |
71,804,832 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7482:Myo9b
|
UTSW |
8 |
71,795,442 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7508:Myo9b
|
UTSW |
8 |
71,807,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7957:Myo9b
|
UTSW |
8 |
71,807,405 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8062:Myo9b
|
UTSW |
8 |
71,774,457 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8108:Myo9b
|
UTSW |
8 |
71,800,986 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8197:Myo9b
|
UTSW |
8 |
71,743,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8274:Myo9b
|
UTSW |
8 |
71,812,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8686:Myo9b
|
UTSW |
8 |
71,786,966 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8731:Myo9b
|
UTSW |
8 |
71,806,486 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8924:Myo9b
|
UTSW |
8 |
71,801,675 (GRCm39) |
missense |
probably benign |
|
|
R9056:Myo9b
|
UTSW |
8 |
71,804,906 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9117:Myo9b
|
UTSW |
8 |
71,800,451 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9151:Myo9b
|
UTSW |
8 |
71,807,871 (GRCm39) |
splice site |
probably benign |
|
|
R9315:Myo9b
|
UTSW |
8 |
71,801,811 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9332:Myo9b
|
UTSW |
8 |
71,812,246 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9364:Myo9b
|
UTSW |
8 |
71,808,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9569:Myo9b
|
UTSW |
8 |
71,811,629 (GRCm39) |
missense |
probably benign |
|
|
R9581:Myo9b
|
UTSW |
8 |
71,812,543 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9600:Myo9b
|
UTSW |
8 |
71,743,075 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
X0066:Myo9b
|
UTSW |
8 |
71,776,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Myo9b
|
UTSW |
8 |
71,743,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
|
| Posted On |
2013-08-08 |
Incidental Mutation