Incidental Mutation 'R0391:Sema6a'
| ID |
65422 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sema6a
|
| Ensembl Gene |
ENSMUSG00000019647 |
| Gene Name |
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| Synonyms |
VIa, Semaq, Sema6A-1, sema, A730020P05Rik |
| MMRRC Submission |
038597-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0391 (G1)
|
| Quality Score |
224 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
47378321-47504267 bp(-) (GRCm39) |
| Type of Mutation |
splice site (1849 bp from exon) |
| DNA Base Change (assembly) |
G to A
at 47423112 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118655
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000019791]
[ENSMUST00000076043]
[ENSMUST00000115449]
[ENSMUST00000126684]
[ENSMUST00000135790]
[ENSMUST00000156422]
|
| AlphaFold |
O35464 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000019791
AA Change: A298V
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000019791
Gene: ENSMUSG00000019647
AA Change: A298V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
Sema
|
56 |
487 |
1.06e-185 |
SMART |
|
PSI
|
514 |
569 |
9.57e-1 |
SMART |
|
transmembrane domain
|
648 |
670 |
N/A |
INTRINSIC |
|
low complexity region
|
932 |
951 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000076043
AA Change: A298V
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000075420
Gene: ENSMUSG00000019647
AA Change: A298V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
Sema
|
56 |
487 |
1.06e-185 |
SMART |
|
PSI
|
514 |
569 |
9.57e-1 |
SMART |
|
transmembrane domain
|
593 |
615 |
N/A |
INTRINSIC |
|
low complexity region
|
877 |
896 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000115449
AA Change: A298V
PolyPhen 2
Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000111109
Gene: ENSMUSG00000019647
AA Change: A298V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
Sema
|
56 |
461 |
1.24e-168 |
SMART |
|
PSI
|
488 |
543 |
9.57e-1 |
SMART |
|
transmembrane domain
|
622 |
644 |
N/A |
INTRINSIC |
|
low complexity region
|
906 |
925 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000126684
|
| SMART Domains |
Protein: ENSMUSP00000118655
Gene: ENSMUSG00000019647
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
Pfam:Sema
|
56 |
216 |
2.5e-51 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000135790
AA Change: A298V
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000120011
Gene: ENSMUSG00000019647
AA Change: A298V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
Sema
|
56 |
487 |
1.06e-185 |
SMART |
|
PSI
|
514 |
569 |
9.57e-1 |
SMART |
|
transmembrane domain
|
665 |
687 |
N/A |
INTRINSIC |
|
low complexity region
|
949 |
968 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141224
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151382
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000156422
AA Change: A298V
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000121442
Gene: ENSMUSG00000019647
AA Change: A298V
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
Sema
|
56 |
487 |
1.06e-185 |
SMART |
|
PSI
|
514 |
569 |
9.57e-1 |
SMART |
|
transmembrane domain
|
648 |
670 |
N/A |
INTRINSIC |
|
low complexity region
|
932 |
951 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.7184 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.8%
|
| Validation Efficiency |
97% (97/100) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit defects in lamina-specific neurite stratification of specific retinal neuron subtypes and disruption of the dendritic plexus organization of On but not Off starburst amacrine cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9530002B09Rik |
T |
A |
4: 122,594,970 (GRCm39) |
|
probably benign |
Het |
| Abcc2 |
G |
A |
19: 43,810,044 (GRCm39) |
|
probably benign |
Het |
| Abcc8 |
C |
G |
7: 45,771,597 (GRCm39) |
G838A |
probably damaging |
Het |
| Akr1c21 |
G |
A |
13: 4,631,199 (GRCm39) |
A245T |
probably damaging |
Het |
| Anapc15-ps |
T |
C |
10: 95,509,139 (GRCm39) |
E47G |
probably damaging |
Het |
| Apoa1 |
A |
G |
9: 46,141,140 (GRCm39) |
T79A |
probably benign |
Het |
| Atp6v1b1 |
A |
G |
6: 83,733,903 (GRCm39) |
H378R |
possibly damaging |
Het |
| C4b |
A |
G |
17: 34,954,588 (GRCm39) |
|
probably benign |
Het |
| Catsperd |
A |
T |
17: 56,969,821 (GRCm39) |
E638D |
probably benign |
Het |
| Cckar |
C |
T |
5: 53,863,595 (GRCm39) |
|
probably null |
Het |
| Cfap100 |
C |
T |
6: 90,382,321 (GRCm39) |
|
probably benign |
Het |
| Chd1 |
G |
T |
17: 15,970,156 (GRCm39) |
G970C |
probably damaging |
Het |
| Col14a1 |
A |
G |
15: 55,309,655 (GRCm39) |
|
probably benign |
Het |
| Col17a1 |
C |
T |
19: 47,652,263 (GRCm39) |
V698M |
probably damaging |
Het |
| Cpeb1 |
T |
C |
7: 81,011,473 (GRCm39) |
D156G |
possibly damaging |
Het |
| Cryl1 |
A |
G |
14: 57,541,232 (GRCm39) |
Y151H |
possibly damaging |
Het |
| Csmd3 |
C |
A |
15: 47,520,969 (GRCm39) |
V1881L |
probably damaging |
Het |
| Ctnnal1 |
C |
T |
4: 56,847,921 (GRCm39) |
A73T |
probably damaging |
Het |
| Cyp2c37 |
T |
C |
19: 39,982,950 (GRCm39) |
S180P |
probably damaging |
Het |
| Cyp2c54 |
T |
C |
19: 40,060,613 (GRCm39) |
T123A |
possibly damaging |
Het |
| Dennd6b |
T |
C |
15: 89,071,417 (GRCm39) |
D304G |
probably damaging |
Het |
| Dnmt3l |
T |
C |
10: 77,887,750 (GRCm39) |
|
probably benign |
Het |
| Eci1 |
G |
A |
17: 24,652,234 (GRCm39) |
|
probably null |
Het |
| Efhc1 |
A |
G |
1: 21,030,412 (GRCm39) |
Y115C |
probably damaging |
Het |
| Ern1 |
T |
A |
11: 106,298,004 (GRCm39) |
K706* |
probably null |
Het |
| Ghrl |
T |
C |
6: 113,696,299 (GRCm39) |
E31G |
probably damaging |
Het |
| Gpr108 |
A |
C |
17: 57,550,101 (GRCm39) |
V179G |
probably benign |
Het |
| Henmt1 |
A |
G |
3: 108,865,851 (GRCm39) |
|
probably benign |
Het |
| Ift172 |
A |
G |
5: 31,444,011 (GRCm39) |
V69A |
probably damaging |
Het |
| Il17ra |
T |
C |
6: 120,453,940 (GRCm39) |
|
probably benign |
Het |
| Il17rb |
T |
C |
14: 29,726,304 (GRCm39) |
N95D |
probably benign |
Het |
| Il17rb |
G |
T |
14: 29,728,112 (GRCm39) |
|
probably null |
Het |
| Iqub |
G |
A |
6: 24,446,154 (GRCm39) |
L757F |
probably benign |
Het |
| Itpr1 |
T |
C |
6: 108,355,128 (GRCm39) |
V473A |
probably benign |
Het |
| Itpr2 |
T |
G |
6: 146,131,271 (GRCm39) |
N1978H |
probably damaging |
Het |
| Klk1b26 |
T |
A |
7: 43,662,151 (GRCm39) |
F3Y |
probably damaging |
Het |
| Lars1 |
A |
G |
18: 42,384,428 (GRCm39) |
V50A |
probably benign |
Het |
| Lax1 |
G |
T |
1: 133,607,804 (GRCm39) |
H312Q |
probably benign |
Het |
| Lctl |
T |
C |
9: 64,029,596 (GRCm39) |
|
probably benign |
Het |
| Lrp2 |
T |
A |
2: 69,287,202 (GRCm39) |
D3745V |
probably damaging |
Het |
| Lrp2 |
G |
A |
2: 69,290,681 (GRCm39) |
|
probably benign |
Het |
| Lvrn |
A |
T |
18: 46,983,533 (GRCm39) |
H92L |
probably benign |
Het |
| Marchf1 |
A |
G |
8: 66,871,625 (GRCm39) |
T385A |
probably damaging |
Het |
| Marf1 |
C |
T |
16: 13,960,398 (GRCm39) |
A549T |
probably damaging |
Het |
| Mbd5 |
T |
C |
2: 49,162,428 (GRCm39) |
V970A |
possibly damaging |
Het |
| Mccc1 |
A |
G |
3: 36,017,719 (GRCm39) |
|
probably benign |
Het |
| Mpp4 |
A |
T |
1: 59,182,988 (GRCm39) |
|
probably benign |
Het |
| Mrnip |
G |
A |
11: 50,090,747 (GRCm39) |
A304T |
probably damaging |
Het |
| Muc5b |
T |
C |
7: 141,418,819 (GRCm39) |
S3922P |
possibly damaging |
Het |
| Myh3 |
T |
A |
11: 66,987,333 (GRCm39) |
|
probably benign |
Het |
| Nbea |
A |
T |
3: 55,944,698 (GRCm39) |
H555Q |
probably damaging |
Het |
| Niban3 |
T |
A |
8: 72,055,143 (GRCm39) |
|
probably benign |
Het |
| Nlrp9c |
A |
T |
7: 26,070,901 (GRCm39) |
|
probably benign |
Het |
| Nmur1 |
A |
T |
1: 86,315,400 (GRCm39) |
V178E |
probably damaging |
Het |
| Nod2 |
T |
G |
8: 89,390,406 (GRCm39) |
S238A |
probably benign |
Het |
| Ogfod1 |
A |
T |
8: 94,789,651 (GRCm39) |
T451S |
probably damaging |
Het |
| Or1e17 |
T |
C |
11: 73,831,935 (GRCm39) |
F288L |
probably damaging |
Het |
| Or2d36 |
T |
A |
7: 106,747,394 (GRCm39) |
Y290* |
probably null |
Het |
| Or2z8 |
C |
T |
8: 72,812,244 (GRCm39) |
T240M |
probably damaging |
Het |
| Or8b8 |
G |
A |
9: 37,809,138 (GRCm39) |
G146D |
probably benign |
Het |
| Pcdh20 |
T |
C |
14: 88,706,104 (GRCm39) |
I399V |
probably benign |
Het |
| Pdlim1 |
G |
T |
19: 40,232,017 (GRCm39) |
H120Q |
probably damaging |
Het |
| Plg |
T |
C |
17: 12,637,968 (GRCm39) |
V798A |
probably damaging |
Het |
| Polr2c |
A |
G |
8: 95,584,403 (GRCm39) |
I39V |
possibly damaging |
Het |
| Ppfia2 |
C |
A |
10: 106,666,575 (GRCm39) |
|
probably benign |
Het |
| Ppp1r3a |
A |
T |
6: 14,719,696 (GRCm39) |
I406N |
probably benign |
Het |
| Psg28 |
A |
T |
7: 18,160,098 (GRCm39) |
M366K |
probably benign |
Het |
| Rad54b |
T |
C |
4: 11,601,702 (GRCm39) |
I419T |
probably damaging |
Het |
| Rnf43 |
A |
G |
11: 87,622,108 (GRCm39) |
Q403R |
possibly damaging |
Het |
| Slc28a3 |
A |
G |
13: 58,717,229 (GRCm39) |
|
probably benign |
Het |
| Smad2 |
A |
T |
18: 76,422,108 (GRCm39) |
|
probably null |
Het |
| Smad4 |
G |
A |
18: 73,791,720 (GRCm39) |
P274S |
probably benign |
Het |
| Smchd1 |
A |
T |
17: 71,710,149 (GRCm39) |
V906D |
probably damaging |
Het |
| Soat2 |
C |
A |
15: 102,067,188 (GRCm39) |
R320S |
possibly damaging |
Het |
| Spata33 |
C |
T |
8: 123,948,626 (GRCm39) |
A57V |
probably damaging |
Het |
| Stab1 |
A |
G |
14: 30,865,375 (GRCm39) |
L1814P |
probably benign |
Het |
| Stab2 |
T |
C |
10: 86,783,008 (GRCm39) |
K680R |
probably benign |
Het |
| Stil |
A |
G |
4: 114,898,369 (GRCm39) |
|
probably null |
Het |
| Sympk |
T |
A |
7: 18,780,774 (GRCm39) |
L759H |
probably benign |
Het |
| Tet1 |
A |
T |
10: 62,650,325 (GRCm39) |
|
probably null |
Het |
| Tfpi2 |
A |
T |
6: 3,965,460 (GRCm39) |
N117K |
probably benign |
Het |
| Tle3 |
A |
G |
9: 61,323,943 (GRCm39) |
Y766C |
probably damaging |
Het |
| Trpt1 |
C |
A |
19: 6,975,298 (GRCm39) |
|
probably null |
Het |
| Tshz1 |
A |
G |
18: 84,034,174 (GRCm39) |
F78S |
possibly damaging |
Het |
| Ttc1 |
T |
C |
11: 43,629,635 (GRCm39) |
D177G |
probably damaging |
Het |
| Ttc13 |
T |
A |
8: 125,401,140 (GRCm39) |
Y741F |
probably damaging |
Het |
| Ulk3 |
C |
T |
9: 57,502,115 (GRCm39) |
S462L |
probably benign |
Het |
| Utrn |
C |
T |
10: 12,401,077 (GRCm39) |
|
probably benign |
Het |
| V1rd19 |
A |
C |
7: 23,703,010 (GRCm39) |
T159P |
probably damaging |
Het |
| Vars1 |
T |
C |
17: 35,230,462 (GRCm39) |
V515A |
possibly damaging |
Het |
| Vmn1r85 |
A |
G |
7: 12,818,515 (GRCm39) |
Y210H |
probably benign |
Het |
| Vmn2r89 |
A |
G |
14: 51,693,435 (GRCm39) |
T262A |
probably damaging |
Het |
| Vps53 |
G |
A |
11: 76,012,405 (GRCm39) |
T209I |
probably benign |
Het |
| Wdfy2 |
T |
C |
14: 63,162,582 (GRCm39) |
F95L |
possibly damaging |
Het |
| Wwp1 |
G |
T |
4: 19,627,911 (GRCm39) |
S694Y |
probably damaging |
Het |
| Zbtb8b |
T |
A |
4: 129,326,463 (GRCm39) |
D201V |
probably damaging |
Het |
| Zmym5 |
A |
C |
14: 57,041,908 (GRCm39) |
N123K |
possibly damaging |
Het |
|
| Other mutations in Sema6a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00336:Sema6a
|
APN |
18 |
47,423,042 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01351:Sema6a
|
APN |
18 |
47,414,369 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL01594:Sema6a
|
APN |
18 |
47,381,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01953:Sema6a
|
APN |
18 |
47,423,187 (GRCm39) |
nonsense |
probably null |
|
|
IGL02077:Sema6a
|
APN |
18 |
47,416,465 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02632:Sema6a
|
APN |
18 |
47,423,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02957:Sema6a
|
APN |
18 |
47,382,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03013:Sema6a
|
APN |
18 |
47,381,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03279:Sema6a
|
APN |
18 |
47,433,157 (GRCm39) |
nonsense |
probably null |
|
|
saphire
|
UTSW |
18 |
47,439,496 (GRCm39) |
nonsense |
probably null |
|
|
IGL02988:Sema6a
|
UTSW |
18 |
47,431,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0114:Sema6a
|
UTSW |
18 |
47,423,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0311:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0312:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0347:Sema6a
|
UTSW |
18 |
47,424,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0350:Sema6a
|
UTSW |
18 |
47,403,785 (GRCm39) |
missense |
probably benign |
|
|
R0366:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0368:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0403:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0466:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0515:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0517:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0542:Sema6a
|
UTSW |
18 |
47,381,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0557:Sema6a
|
UTSW |
18 |
47,382,567 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0569:Sema6a
|
UTSW |
18 |
47,403,872 (GRCm39) |
splice site |
probably null |
|
|
R0650:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0689:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0694:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0726:Sema6a
|
UTSW |
18 |
47,425,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0741:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0821:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0824:Sema6a
|
UTSW |
18 |
47,423,112 (GRCm39) |
splice site |
probably null |
|
|
R0924:Sema6a
|
UTSW |
18 |
47,381,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1108:Sema6a
|
UTSW |
18 |
47,439,498 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1255:Sema6a
|
UTSW |
18 |
47,382,366 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1422:Sema6a
|
UTSW |
18 |
47,439,498 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1531:Sema6a
|
UTSW |
18 |
47,382,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1707:Sema6a
|
UTSW |
18 |
47,416,512 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1746:Sema6a
|
UTSW |
18 |
47,439,416 (GRCm39) |
splice site |
probably benign |
|
|
R1807:Sema6a
|
UTSW |
18 |
47,409,491 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1974:Sema6a
|
UTSW |
18 |
47,403,696 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1987:Sema6a
|
UTSW |
18 |
47,433,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2044:Sema6a
|
UTSW |
18 |
47,439,496 (GRCm39) |
nonsense |
probably null |
|
|
R3719:Sema6a
|
UTSW |
18 |
47,382,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4491:Sema6a
|
UTSW |
18 |
47,439,524 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R4552:Sema6a
|
UTSW |
18 |
47,424,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Sema6a
|
UTSW |
18 |
47,381,779 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4710:Sema6a
|
UTSW |
18 |
47,403,750 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4713:Sema6a
|
UTSW |
18 |
47,382,363 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R4963:Sema6a
|
UTSW |
18 |
47,431,318 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5088:Sema6a
|
UTSW |
18 |
47,382,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5133:Sema6a
|
UTSW |
18 |
47,433,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5135:Sema6a
|
UTSW |
18 |
47,424,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5141:Sema6a
|
UTSW |
18 |
47,381,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5277:Sema6a
|
UTSW |
18 |
47,409,611 (GRCm39) |
intron |
probably benign |
|
|
R5551:Sema6a
|
UTSW |
18 |
47,381,595 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5618:Sema6a
|
UTSW |
18 |
47,415,015 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5717:Sema6a
|
UTSW |
18 |
47,382,330 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5729:Sema6a
|
UTSW |
18 |
47,414,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5779:Sema6a
|
UTSW |
18 |
47,381,893 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5917:Sema6a
|
UTSW |
18 |
47,414,405 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6054:Sema6a
|
UTSW |
18 |
47,416,470 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6142:Sema6a
|
UTSW |
18 |
47,414,266 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6209:Sema6a
|
UTSW |
18 |
47,431,369 (GRCm39) |
splice site |
probably null |
|
|
R6307:Sema6a
|
UTSW |
18 |
47,382,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6734:Sema6a
|
UTSW |
18 |
47,412,236 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7014:Sema6a
|
UTSW |
18 |
47,431,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7033:Sema6a
|
UTSW |
18 |
47,381,637 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7574:Sema6a
|
UTSW |
18 |
47,424,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8054:Sema6a
|
UTSW |
18 |
47,424,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8250:Sema6a
|
UTSW |
18 |
47,423,182 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8408:Sema6a
|
UTSW |
18 |
47,381,958 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8411:Sema6a
|
UTSW |
18 |
47,382,022 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8900:Sema6a
|
UTSW |
18 |
47,424,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9140:Sema6a
|
UTSW |
18 |
47,415,009 (GRCm39) |
missense |
probably benign |
|
|
R9158:Sema6a
|
UTSW |
18 |
47,431,330 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9488:Sema6a
|
UTSW |
18 |
47,437,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9565:Sema6a
|
UTSW |
18 |
47,382,594 (GRCm39) |
missense |
probably null |
1.00 |
|
R9652:Sema6a
|
UTSW |
18 |
47,382,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9732:Sema6a
|
UTSW |
18 |
47,381,925 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0065:Sema6a
|
UTSW |
18 |
47,416,386 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
| Predicted Primers |
|
| Posted On |
2013-08-08 |
Incidental Mutation