Mutagenetix > Incidental Mutation

Incidental Mutation 'K3955:E030025P04Rik'

67244

Institutional Source

Beutler Lab

Gene Symbol

E030025P04Rik

Ensembl Gene

ENSMUSG00000078605

Gene Name

RIKEN cDNA E030025P04 gene

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.102) question?

Stock #

K3955 (G3) of strain 706

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

109030117-109035195 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 109034778 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Serine at position 37 (P37S)

Ref Sequence

ENSEMBL: ENSMUSP00000102321 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000106710]

AlphaFold

A2A6V5

Predicted Effect

unknown
Transcript: ENSMUST00000106710
AA Change: P37S

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.5%
3x: 98.9%
10x: 97.4%
20x: 94.9%

Validation Efficiency

100% (42/42)

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Agap1	G	A	1: 89,815,326 (GRCm39)	R738H	probably damaging	Het
Arhgap28	T	C	17: 68,311,001 (GRCm39)	E2G	probably damaging	Het
Atad2b	C	A	12: 5,004,536 (GRCm39)		probably benign	Het
Atmin	T	A	8: 117,683,775 (GRCm39)	C478*	probably null	Het
Calr	T	C	8: 85,572,902 (GRCm39)	Y57C	probably damaging	Het
Cdh13	G	A	8: 119,401,843 (GRCm39)	V82M	probably damaging	Het
Ces3a	A	T	8: 105,777,259 (GRCm39)		probably benign	Het
Dmbt1	T	C	7: 130,721,293 (GRCm39)	Y1854H	probably damaging	Het
Dnah1	T	A	14: 30,988,416 (GRCm39)	M3429L	probably benign	Het
Dscam	A	G	16: 96,474,887 (GRCm39)	F1225S	probably benign	Het
Eral1	A	T	11: 77,966,847 (GRCm39)	D189E	probably damaging	Het
Fbxw14	G	T	9: 109,105,313 (GRCm39)	P284Q	possibly damaging	Het
Fcrl6	A	G	1: 172,425,251 (GRCm39)	V260A	probably benign	Het
Fezf2	A	T	14: 12,345,097 (GRCm38)	F30Y	probably damaging	Het
Gjb4	A	T	4: 127,245,293 (GRCm39)	V216D	probably benign	Het
Gm9758	G	A	5: 14,963,522 (GRCm39)		probably benign	Het
Gm9758	C	G	5: 14,963,553 (GRCm39)	V92L	probably benign	Het
Gmps	A	C	3: 63,908,954 (GRCm39)	R485S	probably damaging	Het
Gtdc1	C	T	2: 44,642,233 (GRCm39)		probably null	Het
H2-Ob	C	T	17: 34,460,158 (GRCm39)	R19C	probably damaging	Het
Lars2	T	C	9: 123,206,842 (GRCm39)	V103A	probably damaging	Het
Mtrex	A	C	13: 113,047,513 (GRCm39)	Y277*	probably null	Het
Ndnf	G	A	6: 65,678,413 (GRCm39)		probably benign	Het
Nectin1	A	G	9: 43,703,375 (GRCm39)	Y211C	probably damaging	Het
Notch4	C	T	17: 34,787,436 (GRCm39)	T332I	probably damaging	Het
Or13c25	A	G	4: 52,911,081 (GRCm39)	F238L	probably damaging	Het
Or8g28	A	C	9: 39,169,926 (GRCm39)	L14W	probably damaging	Het
Or8g53	A	G	9: 39,683,469 (GRCm39)	I209T	probably benign	Het
Paf1	T	C	7: 28,096,350 (GRCm39)		probably null	Het
Pcdhb1	G	T	18: 37,399,026 (GRCm39)	G326C	probably damaging	Het
Plcl1	A	G	1: 55,737,098 (GRCm39)	Y813C	possibly damaging	Het
Pramel25	T	C	4: 143,521,710 (GRCm39)	I442T	possibly damaging	Het
Prkcq	T	C	2: 11,251,604 (GRCm39)		probably benign	Het
Proser3	G	T	7: 30,242,924 (GRCm39)	P218T	probably damaging	Het
Rccd1	G	A	7: 79,970,419 (GRCm39)	S66F	probably benign	Het
Recql	G	T	6: 142,323,932 (GRCm39)	S54*	probably null	Het
Samd15	G	T	12: 87,247,534 (GRCm39)	G73V	probably benign	Het
Siglec1	T	C	2: 130,923,359 (GRCm39)	N462S	probably benign	Het
Syne2	G	T	12: 75,977,439 (GRCm39)	A1296S	probably damaging	Het
Tlk1	T	C	2: 70,552,045 (GRCm39)	E542G	possibly damaging	Het
Tnks1bp1	C	T	2: 84,892,755 (GRCm39)	T232I	probably benign	Het
Tnrc6c	T	A	11: 117,651,564 (GRCm39)	Y1696N	probably damaging	Het
Uggt1	A	G	1: 36,201,434 (GRCm39)	I1102T	probably benign	Het
Vmn1r84	C	T	7: 12,095,884 (GRCm39)	V270M	probably damaging	Het
Wasf1	C	T	10: 40,812,191 (GRCm39)	P327S	unknown	Het

Other mutations in E030025P04Rik

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01566:E030025P04Rik	APN	11	109,034,714 (GRCm39)	missense	unknown
IGL02709:E030025P04Rik	APN	11	109,030,324 (GRCm39)	utr 3 prime	probably benign
Tipper	UTSW	11	109,030,425 (GRCm39)	missense	unknown
R1842:E030025P04Rik	UTSW	11	109,030,396 (GRCm39)	missense	unknown
R1854:E030025P04Rik	UTSW	11	109,034,744 (GRCm39)	missense	unknown
R2382:E030025P04Rik	UTSW	11	109,034,880 (GRCm39)	nonsense	probably null
R6413:E030025P04Rik	UTSW	11	109,030,425 (GRCm39)	missense	unknown
R6870:E030025P04Rik	UTSW	11	109,030,993 (GRCm39)	missense	unknown
R9121:E030025P04Rik	UTSW	11	109,034,738 (GRCm39)	missense	unknown
R9344:E030025P04Rik	UTSW	11	109,030,454 (GRCm39)	critical splice acceptor site	probably null
R9381:E030025P04Rik	UTSW	11	109,030,384 (GRCm39)	missense	unknown
Z1176:E030025P04Rik	UTSW	11	109,034,797 (GRCm39)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- TCCTCGGTGAAGAAACCCCAGAAG -3'
(R):5'- AACAGAAGTCTTGGCGTGTAACTCC -3'

Sequencing Primer
(F):5'- catctacctgcctctgcc -3'
(R):5'- GTGTAACTCCTGGGCTCTGAC -3'

Posted On

2013-09-03