Incidental Mutation 'R0729:Zfp106'
| ID |
67362 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp106
|
| Ensembl Gene |
ENSMUSG00000027288 |
| Gene Name |
zinc finger protein 106 |
| Synonyms |
Cd-1, H3a, Sh3bp3, sirm |
| MMRRC Submission |
038910-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0729 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
120337301-120394324 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 120385729 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 13
(V13M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055602
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055241]
[ENSMUST00000135625]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000055241
AA Change: V13M
PolyPhen 2
Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000055602
Gene: ENSMUSG00000027288
AA Change: V13M
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
43 |
67 |
7.18e1 |
SMART |
|
low complexity region
|
75 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
141 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
199 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
466 |
480 |
N/A |
INTRINSIC |
|
coiled coil region
|
800 |
823 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1361 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1389 |
1409 |
N/A |
INTRINSIC |
|
WD40
|
1525 |
1562 |
9.24e-4 |
SMART |
|
WD40
|
1565 |
1607 |
1.83e-7 |
SMART |
|
PQQ
|
1587 |
1618 |
3.42e2 |
SMART |
|
WD40
|
1651 |
1691 |
3.45e-1 |
SMART |
|
PQQ
|
1671 |
1702 |
9.14e1 |
SMART |
|
WD40
|
1694 |
1731 |
2.12e-3 |
SMART |
|
PQQ
|
1711 |
1742 |
6.42e0 |
SMART |
|
WD40
|
1734 |
1771 |
6e-3 |
SMART |
|
PQQ
|
1751 |
1782 |
5.7e2 |
SMART |
|
WD40
|
1774 |
1811 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1818 |
1843 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1851 |
1879 |
1.31e2 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000135625
AA Change: V13M
PolyPhen 2
Score 0.758 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000126939
Gene: ENSMUSG00000027288
AA Change: V13M
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
low complexity region
|
53 |
67 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141874
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147353
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000167241
AA Change: V11M
|
| SMART Domains |
Protein: ENSMUSP00000127803
Gene: ENSMUSG00000027288
AA Change: V11M
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
4 |
28 |
1.51e0 |
SMART |
|
low complexity region
|
74 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
132 |
145 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1681 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.8%
- 20x: 96.0%
|
| Validation Efficiency |
97% (74/76) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427D14Rik |
C |
A |
11: 72,050,281 (GRCm39) |
A828S |
probably benign |
Het |
| Acsm3 |
T |
C |
7: 119,383,207 (GRCm39) |
|
probably benign |
Het |
| Adamts12 |
G |
A |
15: 11,255,769 (GRCm39) |
R446H |
possibly damaging |
Het |
| Adgrb1 |
A |
G |
15: 74,420,398 (GRCm39) |
N849S |
probably damaging |
Het |
| Ankra2 |
A |
G |
13: 98,408,235 (GRCm39) |
D228G |
probably damaging |
Het |
| Bicd1 |
T |
C |
6: 149,414,412 (GRCm39) |
V375A |
probably damaging |
Het |
| Blvrb |
A |
G |
7: 27,147,555 (GRCm39) |
K5E |
possibly damaging |
Het |
| Cacna2d2 |
A |
G |
9: 107,394,456 (GRCm39) |
N573D |
probably benign |
Het |
| Calhm2 |
C |
A |
19: 47,121,356 (GRCm39) |
G271V |
possibly damaging |
Het |
| Capn13 |
C |
T |
17: 73,629,064 (GRCm39) |
G581E |
probably damaging |
Het |
| Capzb |
T |
C |
4: 139,016,288 (GRCm39) |
|
probably benign |
Het |
| Casd1 |
T |
C |
6: 4,619,753 (GRCm39) |
|
probably benign |
Het |
| Clca4b |
A |
G |
3: 144,634,111 (GRCm39) |
|
probably benign |
Het |
| Col1a2 |
G |
A |
6: 4,518,822 (GRCm39) |
|
probably benign |
Het |
| Crx |
A |
G |
7: 15,605,058 (GRCm39) |
|
probably benign |
Het |
| Cyp2c68 |
T |
C |
19: 39,727,994 (GRCm39) |
|
probably benign |
Het |
| Dcaf8 |
T |
A |
1: 172,000,221 (GRCm39) |
D126E |
probably benign |
Het |
| Ddx31 |
T |
C |
2: 28,764,186 (GRCm39) |
I464T |
probably damaging |
Het |
| Dhx32 |
G |
A |
7: 133,339,150 (GRCm39) |
T155I |
probably benign |
Het |
| Elac2 |
C |
A |
11: 64,889,349 (GRCm39) |
P567T |
possibly damaging |
Het |
| Fat4 |
A |
G |
3: 39,054,444 (GRCm39) |
|
probably benign |
Het |
| Fh1 |
T |
G |
1: 175,442,383 (GRCm39) |
N156H |
probably damaging |
Het |
| Gm10064 |
T |
C |
5: 122,835,584 (GRCm39) |
|
noncoding transcript |
Het |
| Gm14137 |
A |
G |
2: 119,005,834 (GRCm39) |
E131G |
probably benign |
Het |
| Gpr22 |
T |
A |
12: 31,759,312 (GRCm39) |
K233M |
probably damaging |
Het |
| Gpr63 |
A |
G |
4: 25,007,480 (GRCm39) |
N68S |
probably benign |
Het |
| Gypa |
C |
T |
8: 81,223,421 (GRCm39) |
P66S |
unknown |
Het |
| Htr2a |
A |
T |
14: 74,879,587 (GRCm39) |
Q72L |
probably benign |
Het |
| Klhdc7b |
C |
T |
15: 89,271,598 (GRCm39) |
R827* |
probably null |
Het |
| Leo1 |
G |
A |
9: 75,364,420 (GRCm39) |
R520Q |
possibly damaging |
Het |
| Lrrc66 |
T |
C |
5: 73,765,757 (GRCm39) |
M429V |
probably benign |
Het |
| Lrrc74a |
C |
T |
12: 86,792,353 (GRCm39) |
Q225* |
probably null |
Het |
| Mamdc4 |
T |
A |
2: 25,460,048 (GRCm39) |
N68Y |
probably damaging |
Het |
| Map3k10 |
G |
A |
7: 27,360,992 (GRCm39) |
P507L |
probably damaging |
Het |
| Methig1 |
T |
A |
15: 100,272,870 (GRCm39) |
C68S |
probably benign |
Het |
| Metrn |
C |
T |
17: 26,015,202 (GRCm39) |
|
probably benign |
Het |
| Mmp12 |
C |
T |
9: 7,358,290 (GRCm39) |
T392I |
possibly damaging |
Het |
| Mss51 |
A |
T |
14: 20,533,160 (GRCm39) |
I437N |
probably damaging |
Het |
| Mtus2 |
A |
G |
5: 148,014,097 (GRCm39) |
T297A |
probably benign |
Het |
| Myo10 |
T |
C |
15: 25,722,243 (GRCm39) |
|
probably benign |
Het |
| Ncoa7 |
G |
A |
10: 30,567,575 (GRCm39) |
P319S |
probably benign |
Het |
| Nlrp4d |
A |
T |
7: 10,111,612 (GRCm39) |
|
probably benign |
Het |
| Obscn |
A |
G |
11: 58,923,535 (GRCm39) |
S6455P |
probably damaging |
Het |
| Or5b97 |
T |
C |
19: 12,878,259 (GRCm39) |
N295S |
probably damaging |
Het |
| Or8b37 |
G |
T |
9: 37,959,123 (GRCm39) |
V202L |
probably benign |
Het |
| Pcdh12 |
A |
G |
18: 38,415,517 (GRCm39) |
I536T |
probably benign |
Het |
| Pex5l |
G |
T |
3: 33,008,685 (GRCm39) |
|
probably benign |
Het |
| Pla2g2e |
A |
C |
4: 138,608,046 (GRCm39) |
K43Q |
possibly damaging |
Het |
| Rasa4 |
T |
C |
5: 136,130,924 (GRCm39) |
|
probably benign |
Het |
| Rsf1 |
C |
T |
7: 97,328,234 (GRCm39) |
R1079W |
probably damaging |
Het |
| Sez6 |
A |
G |
11: 77,867,411 (GRCm39) |
T803A |
probably benign |
Het |
| Shcbp1 |
T |
A |
8: 4,786,297 (GRCm39) |
N602Y |
probably benign |
Het |
| Slc16a13 |
G |
A |
11: 70,109,857 (GRCm39) |
P215S |
probably damaging |
Het |
| Slc39a6 |
T |
C |
18: 24,734,527 (GRCm39) |
Q54R |
probably benign |
Het |
| Smg1 |
C |
A |
7: 117,745,512 (GRCm39) |
|
probably benign |
Het |
| Spg7 |
A |
G |
8: 123,797,156 (GRCm39) |
N110D |
probably damaging |
Het |
| Sptbn1 |
A |
T |
11: 30,060,902 (GRCm39) |
S2010T |
probably damaging |
Het |
| Sun1 |
T |
A |
5: 139,223,619 (GRCm39) |
|
probably benign |
Het |
| Sytl5 |
A |
G |
X: 9,860,736 (GRCm39) |
E717G |
probably damaging |
Het |
| Tle1 |
A |
T |
4: 72,044,679 (GRCm39) |
|
probably benign |
Het |
| Tm9sf4 |
T |
A |
2: 153,033,065 (GRCm39) |
V290E |
probably damaging |
Het |
| Tmem63b |
A |
G |
17: 45,985,060 (GRCm39) |
S179P |
probably damaging |
Het |
| Trpm3 |
T |
A |
19: 22,965,153 (GRCm39) |
F1549L |
probably benign |
Het |
| Ubr4 |
A |
T |
4: 139,212,631 (GRCm39) |
Y5063F |
possibly damaging |
Het |
| Uroc1 |
T |
A |
6: 90,313,937 (GRCm39) |
Y75N |
probably damaging |
Het |
| Vmn2r70 |
T |
C |
7: 85,215,112 (GRCm39) |
T141A |
probably benign |
Het |
| Vps13c |
A |
G |
9: 67,868,931 (GRCm39) |
K3128E |
probably damaging |
Het |
| Wdr26 |
T |
C |
1: 181,013,470 (GRCm39) |
|
probably null |
Het |
| Wrn |
T |
A |
8: 33,738,946 (GRCm39) |
|
probably null |
Het |
| Zfp456 |
G |
A |
13: 67,514,663 (GRCm39) |
H348Y |
probably damaging |
Het |
| Zfpm1 |
G |
A |
8: 123,063,398 (GRCm39) |
R819H |
probably benign |
Het |
|
| Other mutations in Zfp106 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Zfp106
|
APN |
2 |
120,369,978 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL00816:Zfp106
|
APN |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00822:Zfp106
|
APN |
2 |
120,344,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00848:Zfp106
|
APN |
2 |
120,343,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01293:Zfp106
|
APN |
2 |
120,365,516 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01323:Zfp106
|
APN |
2 |
120,354,945 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01662:Zfp106
|
APN |
2 |
120,354,034 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01683:Zfp106
|
APN |
2 |
120,355,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01809:Zfp106
|
APN |
2 |
120,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01958:Zfp106
|
APN |
2 |
120,365,288 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL01960:Zfp106
|
APN |
2 |
120,369,803 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01960:Zfp106
|
APN |
2 |
120,354,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02168:Zfp106
|
APN |
2 |
120,364,712 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02623:Zfp106
|
APN |
2 |
120,376,395 (GRCm39) |
splice site |
probably null |
|
|
IGL02798:Zfp106
|
APN |
2 |
120,340,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02828:Zfp106
|
APN |
2 |
120,362,178 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03022:Zfp106
|
APN |
2 |
120,359,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Zfp106
|
APN |
2 |
120,354,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03324:Zfp106
|
APN |
2 |
120,365,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
lepton
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Proton
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
quark
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R0040_zfp106_031
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
string
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
theory
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0135:Zfp106
|
UTSW |
2 |
120,350,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0180:Zfp106
|
UTSW |
2 |
120,364,356 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0387:Zfp106
|
UTSW |
2 |
120,358,953 (GRCm39) |
splice site |
probably null |
|
|
R0558:Zfp106
|
UTSW |
2 |
120,362,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0680:Zfp106
|
UTSW |
2 |
120,357,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0828:Zfp106
|
UTSW |
2 |
120,366,084 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1124:Zfp106
|
UTSW |
2 |
120,365,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1226:Zfp106
|
UTSW |
2 |
120,354,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1239:Zfp106
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1634:Zfp106
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R1754:Zfp106
|
UTSW |
2 |
120,364,245 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1754:Zfp106
|
UTSW |
2 |
120,364,244 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1755:Zfp106
|
UTSW |
2 |
120,365,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Zfp106
|
UTSW |
2 |
120,350,909 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1875:Zfp106
|
UTSW |
2 |
120,344,096 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1903:Zfp106
|
UTSW |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1932:Zfp106
|
UTSW |
2 |
120,362,162 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2070:Zfp106
|
UTSW |
2 |
120,354,010 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2301:Zfp106
|
UTSW |
2 |
120,366,131 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3429:Zfp106
|
UTSW |
2 |
120,357,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3720:Zfp106
|
UTSW |
2 |
120,365,080 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Zfp106
|
UTSW |
2 |
120,365,094 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3881:Zfp106
|
UTSW |
2 |
120,362,630 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3921:Zfp106
|
UTSW |
2 |
120,364,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3923:Zfp106
|
UTSW |
2 |
120,365,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4087:Zfp106
|
UTSW |
2 |
120,357,380 (GRCm39) |
splice site |
probably null |
|
|
R4678:Zfp106
|
UTSW |
2 |
120,364,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4965:Zfp106
|
UTSW |
2 |
120,364,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5011:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Zfp106
|
UTSW |
2 |
120,365,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5227:Zfp106
|
UTSW |
2 |
120,354,449 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5328:Zfp106
|
UTSW |
2 |
120,350,898 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5403:Zfp106
|
UTSW |
2 |
120,365,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5624:Zfp106
|
UTSW |
2 |
120,362,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5686:Zfp106
|
UTSW |
2 |
120,363,988 (GRCm39) |
splice site |
probably null |
|
|
R5691:Zfp106
|
UTSW |
2 |
120,354,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Zfp106
|
UTSW |
2 |
120,346,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6298:Zfp106
|
UTSW |
2 |
120,353,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Zfp106
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6505:Zfp106
|
UTSW |
2 |
120,364,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6598:Zfp106
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R6765:Zfp106
|
UTSW |
2 |
120,369,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7013:Zfp106
|
UTSW |
2 |
120,362,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Zfp106
|
UTSW |
2 |
120,376,400 (GRCm39) |
splice site |
probably null |
|
|
R7453:Zfp106
|
UTSW |
2 |
120,341,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Zfp106
|
UTSW |
2 |
120,343,215 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7829:Zfp106
|
UTSW |
2 |
120,354,538 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7897:Zfp106
|
UTSW |
2 |
120,366,096 (GRCm39) |
nonsense |
probably null |
|
|
R7909:Zfp106
|
UTSW |
2 |
120,344,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8054:Zfp106
|
UTSW |
2 |
120,355,000 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8124:Zfp106
|
UTSW |
2 |
120,354,812 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8203:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8450:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8698:Zfp106
|
UTSW |
2 |
120,354,600 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8985:Zfp106
|
UTSW |
2 |
120,366,077 (GRCm39) |
missense |
|
|
|
R9015:Zfp106
|
UTSW |
2 |
120,364,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9036:Zfp106
|
UTSW |
2 |
120,369,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9142:Zfp106
|
UTSW |
2 |
120,350,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Zfp106
|
UTSW |
2 |
120,364,812 (GRCm39) |
nonsense |
probably null |
|
|
R9175:Zfp106
|
UTSW |
2 |
120,353,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9529:Zfp106
|
UTSW |
2 |
120,351,007 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9572:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9581:Zfp106
|
UTSW |
2 |
120,365,807 (GRCm39) |
missense |
|
|
|
RF008:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
RF025:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
X0025:Zfp106
|
UTSW |
2 |
120,365,297 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Zfp106
|
UTSW |
2 |
120,360,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ggtggggcagtTGAGACTAGCTATAAAA -3'
(R):5'- CCAGGAGGCTGTGCTGTGATAAGA -3'
Sequencing Primer
(F):5'- gatactgccatactcccacc -3'
(R):5'- AGTTCATCAGGGCTGACACTC -3'
|
| Posted On |
2013-09-03 |
Incidental Mutation