Incidental Mutation 'R0731:Ahdc1'
| ID |
67542 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ahdc1
|
| Ensembl Gene |
ENSMUSG00000037692 |
| Gene Name |
AT hook, DNA binding motif, containing 1 |
| Synonyms |
D030015G18Rik |
| MMRRC Submission |
038912-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.214)
|
| Stock # |
R0731 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
132738797-132805421 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 132790262 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 501
(V501E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101536
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044521]
[ENSMUST00000105914]
[ENSMUST00000105915]
[ENSMUST00000105916]
|
| AlphaFold |
Q6PAL7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000044521
AA Change: V501E
PolyPhen 2
Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000047113
Gene: ENSMUSG00000037692
AA Change: V501E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105914
AA Change: V501E
PolyPhen 2
Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000101534
Gene: ENSMUSG00000037692
AA Change: V501E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
Pfam:DUF4683
|
559 |
639 |
6.4e-15 |
PFAM |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105915
AA Change: V501E
PolyPhen 2
Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000101535
Gene: ENSMUSG00000037692
AA Change: V501E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105916
AA Change: V501E
PolyPhen 2
Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000101536
Gene: ENSMUSG00000037692
AA Change: V501E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135548
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142524
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148518
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154482
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156677
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154646
|
| Meta Mutation Damage Score |
0.0605 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.6%
- 20x: 95.5%
|
| Validation Efficiency |
97% (73/75) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing two AT-hooks, which likely function in DNA binding. Mutations in this gene were found in individuals with Xia-Gibbs syndrome. [provided by RefSeq, Jun 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acsm3 |
A |
T |
7: 119,367,247 (GRCm39) |
R27* |
probably null |
Het |
| Actg1 |
A |
G |
11: 120,237,775 (GRCm39) |
F255S |
probably damaging |
Het |
| Alpk2 |
A |
T |
18: 65,438,461 (GRCm39) |
D1444E |
probably damaging |
Het |
| Btaf1 |
T |
G |
19: 36,974,895 (GRCm39) |
|
probably null |
Het |
| Cacnb2 |
A |
G |
2: 14,990,517 (GRCm39) |
H489R |
possibly damaging |
Het |
| Ccdc162 |
C |
A |
10: 41,455,139 (GRCm39) |
K398N |
probably damaging |
Het |
| Cd79b |
G |
T |
11: 106,203,259 (GRCm39) |
S145R |
probably damaging |
Het |
| Cdh11 |
T |
A |
8: 103,394,651 (GRCm39) |
N264Y |
probably damaging |
Het |
| Celsr1 |
T |
C |
15: 85,785,798 (GRCm39) |
D2892G |
probably benign |
Het |
| Chuk |
A |
G |
19: 44,092,205 (GRCm39) |
|
probably benign |
Het |
| Clk3 |
T |
C |
9: 57,658,409 (GRCm39) |
|
probably benign |
Het |
| Dcaf8 |
A |
T |
1: 172,000,076 (GRCm39) |
D78V |
possibly damaging |
Het |
| Dctn1 |
A |
G |
6: 83,160,071 (GRCm39) |
T87A |
probably damaging |
Het |
| Ddx50 |
T |
C |
10: 62,452,028 (GRCm39) |
N732D |
unknown |
Het |
| Dnah5 |
A |
T |
15: 28,311,289 (GRCm39) |
Y1756F |
possibly damaging |
Het |
| Dock3 |
A |
T |
9: 106,847,055 (GRCm39) |
V858E |
probably damaging |
Het |
| Fer1l4 |
A |
G |
2: 155,865,990 (GRCm39) |
F1566S |
probably benign |
Het |
| Fpr-rs7 |
T |
C |
17: 20,334,116 (GRCm39) |
I125V |
probably benign |
Het |
| Fuca2 |
C |
T |
10: 13,381,771 (GRCm39) |
P228L |
probably benign |
Het |
| Galntl6 |
A |
G |
8: 58,989,018 (GRCm39) |
F57L |
probably benign |
Het |
| Gigyf2 |
T |
A |
1: 87,335,449 (GRCm39) |
|
probably benign |
Het |
| Gm16505 |
A |
T |
13: 3,411,329 (GRCm39) |
|
noncoding transcript |
Het |
| Gm4781 |
T |
C |
10: 100,232,639 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9956 |
T |
A |
10: 56,621,639 (GRCm39) |
Y100* |
probably null |
Het |
| Gpr137c |
T |
A |
14: 45,483,806 (GRCm39) |
C178S |
probably damaging |
Het |
| Gpr83 |
A |
G |
9: 14,779,940 (GRCm39) |
R331G |
probably benign |
Het |
| Hlcs |
T |
A |
16: 93,932,711 (GRCm39) |
H851L |
probably damaging |
Het |
| Irag1 |
T |
C |
7: 110,476,107 (GRCm39) |
S615G |
probably benign |
Het |
| Kbtbd6 |
C |
A |
14: 79,689,324 (GRCm39) |
Y6* |
probably null |
Het |
| Kif23 |
T |
C |
9: 61,832,314 (GRCm39) |
R610G |
possibly damaging |
Het |
| Kifc3 |
G |
A |
8: 95,832,361 (GRCm39) |
T487I |
probably damaging |
Het |
| Klra5 |
A |
C |
6: 129,885,759 (GRCm39) |
D133E |
possibly damaging |
Het |
| Klra6 |
T |
C |
6: 129,999,668 (GRCm39) |
E100G |
probably damaging |
Het |
| Klre1 |
T |
A |
6: 129,562,531 (GRCm39) |
|
probably benign |
Het |
| Lancl1 |
C |
T |
1: 67,049,069 (GRCm39) |
|
probably null |
Het |
| Lgr6 |
C |
T |
1: 134,921,748 (GRCm39) |
A199T |
probably damaging |
Het |
| Man1b1 |
A |
G |
2: 25,228,167 (GRCm39) |
I146V |
possibly damaging |
Het |
| Map4k5 |
T |
A |
12: 69,921,038 (GRCm39) |
|
probably benign |
Het |
| Mast3 |
A |
G |
8: 71,233,965 (GRCm39) |
S178P |
probably damaging |
Het |
| Mau2 |
A |
G |
8: 70,476,262 (GRCm39) |
|
probably null |
Het |
| Mgat4f |
A |
C |
1: 134,317,713 (GRCm39) |
M162L |
probably benign |
Het |
| Mkrn2 |
A |
T |
6: 115,591,612 (GRCm39) |
N312Y |
probably damaging |
Het |
| Myh1 |
A |
G |
11: 67,093,359 (GRCm39) |
E150G |
probably damaging |
Het |
| Myo7b |
T |
A |
18: 32,094,878 (GRCm39) |
|
probably null |
Het |
| Nyap1 |
A |
G |
5: 137,733,560 (GRCm39) |
V491A |
probably damaging |
Het |
| Or10a3 |
A |
T |
7: 108,480,740 (GRCm39) |
N24K |
probably damaging |
Het |
| Or4g17 |
A |
G |
2: 111,209,638 (GRCm39) |
M98V |
probably damaging |
Het |
| Or5p60 |
T |
C |
7: 107,723,941 (GRCm39) |
I176M |
probably benign |
Het |
| Or8g34 |
T |
C |
9: 39,372,828 (GRCm39) |
F34L |
probably damaging |
Het |
| Oxsm |
A |
T |
14: 16,240,893 (GRCm38) |
H385Q |
probably damaging |
Het |
| Pbld2 |
T |
C |
10: 62,892,590 (GRCm39) |
S242P |
probably damaging |
Het |
| Pdzd7 |
T |
C |
19: 45,017,744 (GRCm39) |
Y675C |
probably damaging |
Het |
| Pnkd |
T |
A |
1: 74,390,700 (GRCm39) |
H266Q |
probably damaging |
Het |
| Rbfox2 |
A |
G |
15: 76,983,479 (GRCm39) |
S141P |
probably benign |
Het |
| Rdx |
A |
G |
9: 51,979,518 (GRCm39) |
T214A |
probably benign |
Het |
| Ripor2 |
A |
T |
13: 24,864,627 (GRCm39) |
E219V |
probably damaging |
Het |
| Rlig1 |
T |
C |
10: 100,422,065 (GRCm39) |
T66A |
probably damaging |
Het |
| Rufy2 |
G |
A |
10: 62,847,623 (GRCm39) |
|
probably benign |
Het |
| Slf2 |
T |
A |
19: 44,964,165 (GRCm39) |
|
probably benign |
Het |
| Snrnp200 |
G |
T |
2: 127,068,065 (GRCm39) |
|
probably benign |
Het |
| Snx7 |
T |
A |
3: 117,623,320 (GRCm39) |
|
probably benign |
Het |
| Stt3a |
T |
C |
9: 36,646,808 (GRCm39) |
I602V |
probably damaging |
Het |
| Tacr3 |
G |
A |
3: 134,560,761 (GRCm39) |
|
probably null |
Het |
| Tcerg1 |
C |
T |
18: 42,704,905 (GRCm39) |
T978M |
probably damaging |
Het |
| Tcf7l1 |
G |
T |
6: 72,765,252 (GRCm39) |
P126Q |
possibly damaging |
Het |
| Trank1 |
A |
G |
9: 111,194,556 (GRCm39) |
D860G |
probably damaging |
Het |
| Try4 |
T |
C |
6: 41,281,301 (GRCm39) |
L81P |
probably benign |
Het |
| Ucp1 |
T |
C |
8: 84,024,476 (GRCm39) |
|
probably benign |
Het |
| Ugt2b38 |
G |
A |
5: 87,568,311 (GRCm39) |
A328V |
probably damaging |
Het |
| Wfikkn1 |
T |
A |
17: 26,096,991 (GRCm39) |
R444S |
probably damaging |
Het |
| Zfc3h1 |
A |
G |
10: 115,246,537 (GRCm39) |
T875A |
probably benign |
Het |
| Zfp11 |
A |
G |
5: 129,734,328 (GRCm39) |
S378P |
probably damaging |
Het |
| Zfp984 |
T |
A |
4: 147,840,689 (GRCm39) |
N54I |
probably damaging |
Het |
|
| Other mutations in Ahdc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00946:Ahdc1
|
APN |
4 |
132,790,373 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL02293:Ahdc1
|
APN |
4 |
132,792,929 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02338:Ahdc1
|
APN |
4 |
132,789,860 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02828:Ahdc1
|
APN |
4 |
132,790,232 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL02859:Ahdc1
|
APN |
4 |
132,790,004 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02859:Ahdc1
|
APN |
4 |
132,790,003 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02901:Ahdc1
|
APN |
4 |
132,792,245 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL03323:Ahdc1
|
APN |
4 |
132,792,739 (GRCm39) |
missense |
probably benign |
|
|
FR4304:Ahdc1
|
UTSW |
4 |
132,790,070 (GRCm39) |
small insertion |
probably benign |
|
|
FR4548:Ahdc1
|
UTSW |
4 |
132,790,071 (GRCm39) |
small insertion |
probably benign |
|
|
FR4548:Ahdc1
|
UTSW |
4 |
132,790,068 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Ahdc1
|
UTSW |
4 |
132,790,070 (GRCm39) |
small insertion |
probably benign |
|
|
R0325:Ahdc1
|
UTSW |
4 |
132,790,030 (GRCm39) |
missense |
unknown |
|
|
R0550:Ahdc1
|
UTSW |
4 |
132,790,348 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0681:Ahdc1
|
UTSW |
4 |
132,792,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0683:Ahdc1
|
UTSW |
4 |
132,792,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0751:Ahdc1
|
UTSW |
4 |
132,792,707 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1137:Ahdc1
|
UTSW |
4 |
132,789,424 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1184:Ahdc1
|
UTSW |
4 |
132,792,707 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1331:Ahdc1
|
UTSW |
4 |
132,791,002 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1599:Ahdc1
|
UTSW |
4 |
132,792,247 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2202:Ahdc1
|
UTSW |
4 |
132,793,220 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2205:Ahdc1
|
UTSW |
4 |
132,793,220 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2261:Ahdc1
|
UTSW |
4 |
132,790,474 (GRCm39) |
missense |
unknown |
|
|
R2262:Ahdc1
|
UTSW |
4 |
132,790,474 (GRCm39) |
missense |
unknown |
|
|
R3683:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R3684:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R3685:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R3713:Ahdc1
|
UTSW |
4 |
132,793,297 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4027:Ahdc1
|
UTSW |
4 |
132,791,476 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4807:Ahdc1
|
UTSW |
4 |
132,791,624 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4987:Ahdc1
|
UTSW |
4 |
132,791,631 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5126:Ahdc1
|
UTSW |
4 |
132,790,833 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5276:Ahdc1
|
UTSW |
4 |
132,790,109 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5680:Ahdc1
|
UTSW |
4 |
132,792,907 (GRCm39) |
missense |
probably benign |
|
|
R5997:Ahdc1
|
UTSW |
4 |
132,791,206 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6050:Ahdc1
|
UTSW |
4 |
132,793,202 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6271:Ahdc1
|
UTSW |
4 |
132,792,035 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6410:Ahdc1
|
UTSW |
4 |
132,790,210 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6519:Ahdc1
|
UTSW |
4 |
132,792,079 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6970:Ahdc1
|
UTSW |
4 |
132,789,656 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7199:Ahdc1
|
UTSW |
4 |
132,791,935 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7202:Ahdc1
|
UTSW |
4 |
132,789,198 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Ahdc1
|
UTSW |
4 |
132,792,313 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7614:Ahdc1
|
UTSW |
4 |
132,790,825 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7794:Ahdc1
|
UTSW |
4 |
132,791,289 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7875:Ahdc1
|
UTSW |
4 |
132,791,161 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8016:Ahdc1
|
UTSW |
4 |
132,790,226 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8295:Ahdc1
|
UTSW |
4 |
132,788,762 (GRCm39) |
start codon destroyed |
probably null |
0.53 |
|
R8332:Ahdc1
|
UTSW |
4 |
132,791,282 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8719:Ahdc1
|
UTSW |
4 |
132,791,533 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8725:Ahdc1
|
UTSW |
4 |
132,792,743 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8862:Ahdc1
|
UTSW |
4 |
132,791,129 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9158:Ahdc1
|
UTSW |
4 |
132,792,505 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9179:Ahdc1
|
UTSW |
4 |
132,788,929 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9362:Ahdc1
|
UTSW |
4 |
132,790,348 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9428:Ahdc1
|
UTSW |
4 |
132,791,773 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
RF017:Ahdc1
|
UTSW |
4 |
132,790,062 (GRCm39) |
small insertion |
probably benign |
|
|
RF020:Ahdc1
|
UTSW |
4 |
132,791,588 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
T0722:Ahdc1
|
UTSW |
4 |
132,790,065 (GRCm39) |
small insertion |
probably benign |
|
|
T0975:Ahdc1
|
UTSW |
4 |
132,790,065 (GRCm39) |
small insertion |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTCTTCTCAAACCCCGATGGTCC -3'
(R):5'- ATTGGCGTCTGCTGCATACGATGG -3'
Sequencing Primer
(F):5'- GGTCCCCACCCGCAAAG -3'
(R):5'- TGTCACAGTAGCAGCCTCAG -3'
|
| Posted On |
2013-09-03 |
Incidental Mutation