Incidental Mutation 'R0732:Pcdh7'
| ID |
67629 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdh7
|
| Ensembl Gene |
ENSMUSG00000029108 |
| Gene Name |
protocadherin 7 |
| Synonyms |
BH-protocadherin |
| MMRRC Submission |
038913-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.119)
|
| Stock # |
R0732 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
57875309-58290572 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 57878657 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 737
(D737E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142319
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068110]
[ENSMUST00000094783]
[ENSMUST00000191837]
[ENSMUST00000199310]
|
| AlphaFold |
A0A0A6YY83 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000068110
AA Change: D737E
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000066306
Gene: ENSMUSG00000029108
AA Change: D737E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000094783
AA Change: D737E
|
| SMART Domains |
Protein: ENSMUSP00000092376
Gene: ENSMUSG00000029108
AA Change: D737E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180708
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000191837
AA Change: D737E
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142319
Gene: ENSMUSG00000029108
AA Change: D737E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192048
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000192287
AA Change: D397E
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000193156
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000195156
AA Change: D51E
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200266
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199310
|
| SMART Domains |
Protein: ENSMUSP00000143387
Gene: ENSMUSG00000029108
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Protocadherin
|
1 |
79 |
5.1e-40 |
PFAM |
|
low complexity region
|
112 |
123 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.8%
- 10x: 97.4%
- 20x: 94.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2ml1 |
T |
C |
6: 128,523,411 (GRCm39) |
Y1175C |
probably damaging |
Het |
| Acsm3 |
T |
C |
7: 119,373,057 (GRCm39) |
S187P |
probably benign |
Het |
| Adam28 |
T |
C |
14: 68,874,796 (GRCm39) |
I294V |
probably benign |
Het |
| Adgrv1 |
T |
C |
13: 81,651,123 (GRCm39) |
I3057M |
possibly damaging |
Het |
| Aff4 |
T |
C |
11: 53,266,423 (GRCm39) |
V304A |
probably benign |
Het |
| Akr1b10 |
T |
C |
6: 34,367,044 (GRCm39) |
Y108H |
probably benign |
Het |
| Ankib1 |
T |
C |
5: 3,763,163 (GRCm39) |
N522S |
possibly damaging |
Het |
| Ano1 |
T |
A |
7: 144,173,225 (GRCm39) |
|
probably null |
Het |
| Antxr2 |
G |
T |
5: 98,108,567 (GRCm39) |
|
probably null |
Het |
| Arc |
G |
A |
15: 74,543,044 (GRCm39) |
T393I |
probably damaging |
Het |
| Arhgef33 |
A |
G |
17: 80,688,783 (GRCm39) |
D5G |
possibly damaging |
Het |
| Atf2 |
A |
T |
2: 73,675,844 (GRCm39) |
M169K |
possibly damaging |
Het |
| BC005624 |
T |
A |
2: 30,863,949 (GRCm39) |
T215S |
possibly damaging |
Het |
| Bmp8b |
G |
A |
4: 122,999,199 (GRCm39) |
G19D |
unknown |
Het |
| Cacna1d |
T |
C |
14: 29,764,877 (GRCm39) |
N1987S |
probably damaging |
Het |
| Camta1 |
T |
A |
4: 151,670,941 (GRCm39) |
|
probably null |
Het |
| Catsperg2 |
C |
T |
7: 29,400,121 (GRCm39) |
G316D |
probably damaging |
Het |
| Cbs |
G |
T |
17: 31,844,003 (GRCm39) |
N209K |
probably benign |
Het |
| Ccdc122 |
T |
A |
14: 77,329,199 (GRCm39) |
M84K |
probably damaging |
Het |
| Cd5 |
C |
T |
19: 10,700,649 (GRCm39) |
C285Y |
probably damaging |
Het |
| Chpf2 |
T |
C |
5: 24,795,419 (GRCm39) |
M1T |
probably null |
Het |
| Coch |
T |
A |
12: 51,642,155 (GRCm39) |
D42E |
probably damaging |
Het |
| Crip2 |
C |
T |
12: 113,104,178 (GRCm39) |
|
probably benign |
Het |
| Crlf2 |
G |
C |
5: 109,705,004 (GRCm39) |
P67R |
probably damaging |
Het |
| Cxcl16 |
G |
T |
11: 70,346,234 (GRCm39) |
P233H |
probably damaging |
Het |
| Cyfip1 |
T |
C |
7: 55,536,529 (GRCm39) |
I319T |
probably damaging |
Het |
| Ddhd2 |
T |
C |
8: 26,231,348 (GRCm39) |
Q364R |
probably damaging |
Het |
| Ephx2 |
A |
G |
14: 66,324,412 (GRCm39) |
|
probably null |
Het |
| Exoc6b |
C |
A |
6: 84,832,504 (GRCm39) |
V397L |
probably damaging |
Het |
| Fam83b |
T |
A |
9: 76,400,210 (GRCm39) |
K298* |
probably null |
Het |
| Fbxo8 |
T |
A |
8: 57,044,564 (GRCm39) |
I289N |
probably damaging |
Het |
| Fkbp9 |
T |
A |
6: 56,855,089 (GRCm39) |
M536K |
probably benign |
Het |
| Flot1 |
C |
T |
17: 36,136,416 (GRCm39) |
R190W |
possibly damaging |
Het |
| Gbp2b |
T |
A |
3: 142,312,739 (GRCm39) |
V374E |
probably benign |
Het |
| Gna15 |
T |
A |
10: 81,348,390 (GRCm39) |
S114C |
probably damaging |
Het |
| Gstt4 |
T |
A |
10: 75,653,155 (GRCm39) |
T136S |
probably benign |
Het |
| Hcn3 |
C |
T |
3: 89,056,093 (GRCm39) |
V524M |
probably damaging |
Het |
| Kctd16 |
A |
T |
18: 40,391,616 (GRCm39) |
D68V |
probably damaging |
Het |
| Kics2 |
T |
C |
10: 121,586,852 (GRCm39) |
V253A |
possibly damaging |
Het |
| Krt90 |
G |
T |
15: 101,468,860 (GRCm39) |
F227L |
possibly damaging |
Het |
| Lrrc37 |
T |
C |
11: 103,510,664 (GRCm39) |
T435A |
unknown |
Het |
| Maip1 |
A |
G |
1: 57,450,994 (GRCm39) |
Y212C |
probably damaging |
Het |
| Mamdc2 |
C |
T |
19: 23,356,233 (GRCm39) |
D72N |
probably damaging |
Het |
| Marveld3 |
A |
T |
8: 110,675,115 (GRCm39) |
Y234N |
probably damaging |
Het |
| Mas1 |
A |
G |
17: 13,060,634 (GRCm39) |
I263T |
probably benign |
Het |
| Matk |
T |
A |
10: 81,094,140 (GRCm39) |
|
probably null |
Het |
| Mrgpre |
T |
A |
7: 143,335,303 (GRCm39) |
I67F |
possibly damaging |
Het |
| Mthfd1 |
T |
A |
12: 76,340,948 (GRCm39) |
I449N |
probably damaging |
Het |
| Nacc1 |
C |
T |
8: 85,402,830 (GRCm39) |
R321Q |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,148,693 (GRCm39) |
D2618G |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,181,280 (GRCm39) |
Y1109C |
probably damaging |
Het |
| Nell1 |
T |
G |
7: 50,506,135 (GRCm39) |
W781G |
probably damaging |
Het |
| Or4g16 |
T |
A |
2: 111,137,325 (GRCm39) |
Y258* |
probably null |
Het |
| Or4x6 |
A |
G |
2: 89,949,666 (GRCm39) |
V92A |
probably benign |
Het |
| Or52d1 |
T |
C |
7: 103,755,501 (GRCm39) |
L5P |
probably damaging |
Het |
| Or55b4 |
T |
C |
7: 102,133,650 (GRCm39) |
I226V |
probably benign |
Het |
| Or5p72 |
C |
A |
7: 108,021,784 (GRCm39) |
A2D |
probably benign |
Het |
| Or6k4 |
A |
T |
1: 173,964,981 (GRCm39) |
I224F |
possibly damaging |
Het |
| Or8s8 |
T |
C |
15: 98,354,959 (GRCm39) |
L256S |
possibly damaging |
Het |
| Or8u10 |
A |
C |
2: 85,915,928 (GRCm39) |
S64R |
probably benign |
Het |
| Pdss1 |
T |
G |
2: 22,791,324 (GRCm39) |
M55R |
probably benign |
Het |
| Pex6 |
C |
T |
17: 47,035,626 (GRCm39) |
R889W |
probably damaging |
Het |
| Pigl |
T |
A |
11: 62,349,307 (GRCm39) |
C8S |
possibly damaging |
Het |
| Plekha7 |
A |
T |
7: 115,744,472 (GRCm39) |
M585K |
probably damaging |
Het |
| Ppp1r1a |
C |
T |
15: 103,441,514 (GRCm39) |
M66I |
possibly damaging |
Het |
| Ptcd3 |
A |
T |
6: 71,858,155 (GRCm39) |
|
probably benign |
Het |
| Rhov |
A |
T |
2: 119,101,495 (GRCm39) |
V37E |
probably damaging |
Het |
| Rnf213 |
A |
T |
11: 119,331,894 (GRCm39) |
M2368L |
probably damaging |
Het |
| Skida1 |
T |
C |
2: 18,050,968 (GRCm39) |
|
probably benign |
Het |
| Slc25a28 |
T |
C |
19: 43,655,392 (GRCm39) |
D161G |
probably benign |
Het |
| Smc6 |
T |
C |
12: 11,340,818 (GRCm39) |
V490A |
probably damaging |
Het |
| Sohlh2 |
T |
A |
3: 55,097,794 (GRCm39) |
|
probably null |
Het |
| Stk31 |
A |
G |
6: 49,394,429 (GRCm39) |
T264A |
probably benign |
Het |
| Syngap1 |
T |
A |
17: 27,173,962 (GRCm39) |
S190R |
possibly damaging |
Het |
| Tacr1 |
T |
A |
6: 82,529,882 (GRCm39) |
V200E |
probably damaging |
Het |
| Tbrg4 |
C |
T |
11: 6,570,812 (GRCm39) |
R220H |
probably benign |
Het |
| Tcf20 |
A |
G |
15: 82,736,504 (GRCm39) |
L1649P |
probably benign |
Het |
| Tcirg1 |
A |
T |
19: 3,947,866 (GRCm39) |
L523Q |
possibly damaging |
Het |
| Tinag |
T |
A |
9: 76,908,936 (GRCm39) |
K335M |
possibly damaging |
Het |
| Tkt |
T |
G |
14: 30,293,097 (GRCm39) |
|
probably null |
Het |
| Tnpo1 |
C |
T |
13: 99,000,320 (GRCm39) |
R349H |
probably damaging |
Het |
| Trim26 |
T |
A |
17: 37,163,510 (GRCm39) |
S230R |
possibly damaging |
Het |
| Trim8 |
T |
A |
19: 46,503,178 (GRCm39) |
|
probably null |
Het |
| Trp53bp1 |
T |
C |
2: 121,078,745 (GRCm39) |
R326G |
probably null |
Het |
| Ugt2a2 |
A |
T |
5: 87,608,498 (GRCm39) |
I613N |
probably damaging |
Het |
| Vmn1r32 |
T |
C |
6: 66,530,690 (GRCm39) |
I29V |
probably benign |
Het |
| Wnt5b |
C |
T |
6: 119,423,543 (GRCm39) |
W27* |
probably null |
Het |
|
| Other mutations in Pcdh7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Pcdh7
|
APN |
5 |
57,878,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00920:Pcdh7
|
APN |
5 |
57,877,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00990:Pcdh7
|
APN |
5 |
57,877,806 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01367:Pcdh7
|
APN |
5 |
58,286,566 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL01388:Pcdh7
|
APN |
5 |
57,877,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01543:Pcdh7
|
APN |
5 |
57,878,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01750:Pcdh7
|
APN |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Pcdh7
|
APN |
5 |
58,286,597 (GRCm39) |
missense |
probably benign |
|
|
IGL02014:Pcdh7
|
APN |
5 |
57,877,045 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02269:Pcdh7
|
APN |
5 |
58,070,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03051:Pcdh7
|
APN |
5 |
58,286,415 (GRCm39) |
missense |
probably damaging |
0.99 |
|
floated
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
proposed
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0037:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0003:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0421:Pcdh7
|
UTSW |
5 |
57,877,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0551:Pcdh7
|
UTSW |
5 |
57,879,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Pcdh7
|
UTSW |
5 |
57,877,405 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0755:Pcdh7
|
UTSW |
5 |
57,877,664 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1080:Pcdh7
|
UTSW |
5 |
57,876,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1381:Pcdh7
|
UTSW |
5 |
57,878,882 (GRCm39) |
nonsense |
probably null |
|
|
R1591:Pcdh7
|
UTSW |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1891:Pcdh7
|
UTSW |
5 |
57,878,217 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2011:Pcdh7
|
UTSW |
5 |
57,876,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Pcdh7
|
UTSW |
5 |
58,286,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:Pcdh7
|
UTSW |
5 |
58,286,458 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R2848:Pcdh7
|
UTSW |
5 |
57,877,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Pcdh7
|
UTSW |
5 |
58,286,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4075:Pcdh7
|
UTSW |
5 |
57,879,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4231:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4236:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4352:Pcdh7
|
UTSW |
5 |
57,879,361 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4420:Pcdh7
|
UTSW |
5 |
58,286,512 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4449:Pcdh7
|
UTSW |
5 |
57,877,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Pcdh7
|
UTSW |
5 |
57,878,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4686:Pcdh7
|
UTSW |
5 |
58,286,511 (GRCm39) |
missense |
probably benign |
|
|
R4837:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4838:Pcdh7
|
UTSW |
5 |
57,878,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4947:Pcdh7
|
UTSW |
5 |
57,879,258 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5053:Pcdh7
|
UTSW |
5 |
57,878,943 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5068:Pcdh7
|
UTSW |
5 |
57,879,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5117:Pcdh7
|
UTSW |
5 |
57,879,090 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5132:Pcdh7
|
UTSW |
5 |
57,885,463 (GRCm39) |
missense |
probably benign |
|
|
R5248:Pcdh7
|
UTSW |
5 |
58,286,515 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5294:Pcdh7
|
UTSW |
5 |
57,885,453 (GRCm39) |
splice site |
probably null |
|
|
R5420:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5777:Pcdh7
|
UTSW |
5 |
57,876,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5800:Pcdh7
|
UTSW |
5 |
57,879,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5834:Pcdh7
|
UTSW |
5 |
57,878,970 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5870:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5917:Pcdh7
|
UTSW |
5 |
57,879,097 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6014:Pcdh7
|
UTSW |
5 |
57,878,497 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6193:Pcdh7
|
UTSW |
5 |
57,877,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6240:Pcdh7
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Pcdh7
|
UTSW |
5 |
58,099,607 (GRCm39) |
splice site |
probably null |
|
|
R6418:Pcdh7
|
UTSW |
5 |
57,879,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6907:Pcdh7
|
UTSW |
5 |
57,876,471 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7058:Pcdh7
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7069:Pcdh7
|
UTSW |
5 |
57,877,126 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7073:Pcdh7
|
UTSW |
5 |
57,878,299 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7463:Pcdh7
|
UTSW |
5 |
57,878,340 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7509:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7588:Pcdh7
|
UTSW |
5 |
57,877,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7707:Pcdh7
|
UTSW |
5 |
57,877,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Pcdh7
|
UTSW |
5 |
57,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7899:Pcdh7
|
UTSW |
5 |
57,877,152 (GRCm39) |
missense |
probably benign |
|
|
R8194:Pcdh7
|
UTSW |
5 |
57,877,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8480:Pcdh7
|
UTSW |
5 |
58,286,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8890:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Pcdh7
|
UTSW |
5 |
57,879,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8990:Pcdh7
|
UTSW |
5 |
57,879,364 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9264:Pcdh7
|
UTSW |
5 |
58,286,663 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9272:Pcdh7
|
UTSW |
5 |
57,878,779 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9294:Pcdh7
|
UTSW |
5 |
57,878,677 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9518:Pcdh7
|
UTSW |
5 |
58,070,513 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9597:Pcdh7
|
UTSW |
5 |
57,877,197 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9642:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Pcdh7
|
UTSW |
5 |
57,879,622 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0021:Pcdh7
|
UTSW |
5 |
57,878,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
X0026:Pcdh7
|
UTSW |
5 |
57,876,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Pcdh7
|
UTSW |
5 |
57,877,006 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCACCGTGATGGATGCTGACAAG -3'
(R):5'- GCCTGTGCAAGCCATAATGCTTC -3'
Sequencing Primer
(F):5'- TGCAGAGATGAGCCTGTACATAG -3'
(R):5'- CTGGGTGAGTTTCCCCACTAAG -3'
|
| Posted On |
2013-09-03 |
Incidental Mutation