Incidental Mutation 'R0734:Adamts16'
| ID |
68171 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamts16
|
| Ensembl Gene |
ENSMUSG00000049538 |
| Gene Name |
ADAM metallopeptidase with thrombospondin type 1 motif 16 |
| Synonyms |
|
| MMRRC Submission |
038915-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0734 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
70875921-70989930 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to G
at 70886600 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000122031
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080145]
[ENSMUST00000080145]
[ENSMUST00000123552]
|
| AlphaFold |
Q69Z28 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080145
|
| SMART Domains |
Protein: ENSMUSP00000079041
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
57 |
203 |
7.8e-34 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
2.9e-13 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
1.2e-8 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
5.4e-32 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
3.7e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
6.4e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
Pfam:ADAM_spacer1
|
744 |
856 |
1.3e-37 |
PFAM |
|
TSP1
|
872 |
926 |
3.48e0 |
SMART |
|
TSP1
|
928 |
985 |
4.84e-3 |
SMART |
|
TSP1
|
987 |
1046 |
1.49e-3 |
SMART |
|
TSP1
|
1052 |
1113 |
3.19e-2 |
SMART |
|
TSP1
|
1127 |
1179 |
7.68e-6 |
SMART |
|
Pfam:PLAC
|
1188 |
1218 |
2.9e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080145
|
| SMART Domains |
Protein: ENSMUSP00000079041
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
57 |
203 |
7.8e-34 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
2.9e-13 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
1.2e-8 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
5.4e-32 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
3.7e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
6.4e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
Pfam:ADAM_spacer1
|
744 |
856 |
1.3e-37 |
PFAM |
|
TSP1
|
872 |
926 |
3.48e0 |
SMART |
|
TSP1
|
928 |
985 |
4.84e-3 |
SMART |
|
TSP1
|
987 |
1046 |
1.49e-3 |
SMART |
|
TSP1
|
1052 |
1113 |
3.19e-2 |
SMART |
|
TSP1
|
1127 |
1179 |
7.68e-6 |
SMART |
|
Pfam:PLAC
|
1188 |
1218 |
2.9e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123552
|
| SMART Domains |
Protein: ENSMUSP00000122031
Gene: ENSMUSG00000049538
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
36 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
56 |
203 |
5.9e-33 |
PFAM |
|
Pfam:Reprolysin_5
|
287 |
470 |
5.1e-14 |
PFAM |
|
Pfam:Reprolysin_4
|
289 |
489 |
2.2e-9 |
PFAM |
|
Pfam:Reprolysin
|
289 |
493 |
1.2e-33 |
PFAM |
|
Pfam:Reprolysin_2
|
306 |
483 |
1.2e-10 |
PFAM |
|
Pfam:Reprolysin_3
|
310 |
442 |
9.7e-11 |
PFAM |
|
TSP1
|
587 |
639 |
1.43e-14 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.5%
- 3x: 98.8%
- 10x: 97.0%
- 20x: 93.3%
|
| Validation Efficiency |
99% (80/81) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is co-expressed with the Wilms tumor protein, Wt1, in the developing glomeruli of embryonic kidneys. The encoded preproprotein undergoes proteolytic processing to generate an active enzyme. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
T |
A |
16: 4,668,198 (GRCm39) |
S530T |
probably benign |
Het |
| Acer2 |
G |
T |
4: 86,835,796 (GRCm39) |
K223N |
probably benign |
Het |
| Adam19 |
T |
G |
11: 46,018,230 (GRCm39) |
C431G |
probably damaging |
Het |
| Aox1 |
A |
T |
1: 58,344,500 (GRCm39) |
E531V |
probably benign |
Het |
| Apaf1 |
A |
T |
10: 90,872,883 (GRCm39) |
N720K |
probably benign |
Het |
| Atrnl1 |
T |
A |
19: 57,643,293 (GRCm39) |
W394R |
probably damaging |
Het |
| Bcl6 |
T |
C |
16: 23,786,889 (GRCm39) |
E634G |
probably damaging |
Het |
| Cfap65 |
T |
A |
1: 74,958,046 (GRCm39) |
Y954F |
probably damaging |
Het |
| Cobl |
A |
G |
11: 12,325,971 (GRCm39) |
V168A |
probably damaging |
Het |
| Cped1 |
C |
T |
6: 22,085,040 (GRCm39) |
P210S |
probably damaging |
Het |
| Crb1 |
C |
T |
1: 139,264,822 (GRCm39) |
V199M |
probably benign |
Het |
| Cyp2j6 |
A |
T |
4: 96,412,081 (GRCm39) |
|
probably benign |
Het |
| Dhrs3 |
C |
G |
4: 144,653,746 (GRCm39) |
S289W |
probably damaging |
Het |
| Dido1 |
T |
G |
2: 180,301,835 (GRCm39) |
Q2023P |
probably benign |
Het |
| Dlg4 |
G |
A |
11: 69,933,531 (GRCm39) |
G550R |
probably damaging |
Het |
| Dnah12 |
C |
A |
14: 26,521,970 (GRCm39) |
H1928N |
probably benign |
Het |
| Dthd1 |
A |
C |
5: 62,996,753 (GRCm39) |
|
probably benign |
Het |
| Erg |
C |
A |
16: 95,170,884 (GRCm39) |
G269C |
possibly damaging |
Het |
| Erich6 |
G |
A |
3: 58,536,809 (GRCm39) |
|
probably benign |
Het |
| F5 |
G |
C |
1: 164,026,486 (GRCm39) |
R1686P |
probably damaging |
Het |
| Fancc |
T |
C |
13: 63,479,656 (GRCm39) |
R300G |
probably damaging |
Het |
| Fcer1g |
T |
A |
1: 171,058,748 (GRCm39) |
K47* |
probably null |
Het |
| Flt4 |
A |
G |
11: 49,517,544 (GRCm39) |
T289A |
possibly damaging |
Het |
| Gcnt2 |
T |
A |
13: 41,013,997 (GRCm39) |
F56Y |
probably benign |
Het |
| Gpatch8 |
G |
T |
11: 102,372,226 (GRCm39) |
S437R |
unknown |
Het |
| Grin2a |
T |
A |
16: 9,397,475 (GRCm39) |
I871F |
possibly damaging |
Het |
| Hsd17b4 |
T |
C |
18: 50,303,844 (GRCm39) |
V439A |
possibly damaging |
Het |
| Hykk |
A |
T |
9: 54,853,716 (GRCm39) |
K346M |
possibly damaging |
Het |
| Ifi208 |
T |
C |
1: 173,510,901 (GRCm39) |
L352S |
probably damaging |
Het |
| Ikzf1 |
T |
C |
11: 11,708,195 (GRCm39) |
V110A |
probably damaging |
Het |
| Irak3 |
A |
T |
10: 119,981,542 (GRCm39) |
|
probably benign |
Het |
| Lamp5 |
T |
A |
2: 135,900,950 (GRCm39) |
V50E |
probably damaging |
Het |
| Lgr6 |
C |
T |
1: 134,921,748 (GRCm39) |
A199T |
probably damaging |
Het |
| Lrch3 |
C |
T |
16: 32,817,853 (GRCm39) |
R570* |
probably null |
Het |
| Map1lc3a |
T |
C |
2: 155,118,896 (GRCm39) |
V20A |
possibly damaging |
Het |
| Map3k14 |
C |
A |
11: 103,117,826 (GRCm39) |
K655N |
probably benign |
Het |
| Mark2 |
A |
G |
19: 7,263,346 (GRCm39) |
|
probably benign |
Het |
| Mbtd1 |
G |
A |
11: 93,813,972 (GRCm39) |
G205D |
probably damaging |
Het |
| Med13 |
T |
C |
11: 86,192,063 (GRCm39) |
T861A |
probably benign |
Het |
| Meltf |
T |
A |
16: 31,700,776 (GRCm39) |
Y99N |
probably damaging |
Het |
| Mex3d |
G |
A |
10: 80,217,366 (GRCm39) |
T617I |
possibly damaging |
Het |
| Muc13 |
G |
A |
16: 33,623,452 (GRCm39) |
V249I |
probably damaging |
Het |
| Myo18a |
C |
A |
11: 77,738,230 (GRCm39) |
P1688Q |
probably damaging |
Het |
| Naaladl1 |
A |
T |
19: 6,162,904 (GRCm39) |
|
probably null |
Het |
| Ncoa3 |
T |
A |
2: 165,911,111 (GRCm39) |
|
probably benign |
Het |
| Nf2 |
T |
C |
11: 4,770,409 (GRCm39) |
T67A |
probably benign |
Het |
| Nin |
A |
G |
12: 70,076,887 (GRCm39) |
V1056A |
probably benign |
Het |
| Or1p1 |
A |
T |
11: 74,179,772 (GRCm39) |
Q100L |
probably damaging |
Het |
| Or4d10c |
T |
A |
19: 12,065,483 (GRCm39) |
R224S |
probably benign |
Het |
| Or5b105 |
G |
A |
19: 13,080,642 (GRCm39) |
R3C |
possibly damaging |
Het |
| P3h1 |
T |
C |
4: 119,095,885 (GRCm39) |
L331P |
probably damaging |
Het |
| Pabpc4l |
T |
C |
3: 46,401,408 (GRCm39) |
K79E |
possibly damaging |
Het |
| Pam |
T |
A |
1: 97,792,087 (GRCm39) |
R445* |
probably null |
Het |
| Pcdhb6 |
T |
C |
18: 37,468,387 (GRCm39) |
I436T |
probably damaging |
Het |
| Piezo2 |
A |
G |
18: 63,174,794 (GRCm39) |
Y1987H |
probably damaging |
Het |
| Plch2 |
G |
A |
4: 155,080,740 (GRCm39) |
T477I |
probably damaging |
Het |
| Postn |
G |
A |
3: 54,270,136 (GRCm39) |
G72R |
probably damaging |
Het |
| Proca1 |
G |
A |
11: 78,092,628 (GRCm39) |
|
probably benign |
Het |
| Psip1 |
T |
A |
4: 83,381,825 (GRCm39) |
|
probably benign |
Het |
| Ptprd |
G |
A |
4: 76,058,834 (GRCm39) |
P153L |
probably damaging |
Het |
| Rgl1 |
T |
C |
1: 152,430,051 (GRCm39) |
D242G |
probably damaging |
Het |
| Ric1 |
T |
A |
19: 29,572,218 (GRCm39) |
I671K |
possibly damaging |
Het |
| Rxrg |
T |
A |
1: 167,455,013 (GRCm39) |
C199S |
probably damaging |
Het |
| Sec24c |
A |
C |
14: 20,743,813 (GRCm39) |
D1006A |
probably damaging |
Het |
| Sec63 |
A |
G |
10: 42,672,204 (GRCm39) |
T173A |
probably benign |
Het |
| Sfxn5 |
T |
C |
6: 85,244,847 (GRCm39) |
|
probably benign |
Het |
| Spam1 |
A |
G |
6: 24,796,948 (GRCm39) |
I300V |
probably benign |
Het |
| Spem1 |
A |
G |
11: 69,712,097 (GRCm39) |
L189P |
probably damaging |
Het |
| Sptbn2 |
A |
T |
19: 4,798,151 (GRCm39) |
R1959* |
probably null |
Het |
| Timeless |
C |
T |
10: 128,085,929 (GRCm39) |
R935W |
probably damaging |
Het |
| Tnfrsf21 |
C |
T |
17: 43,349,104 (GRCm39) |
H239Y |
probably benign |
Het |
| Trim24 |
T |
C |
6: 37,896,400 (GRCm39) |
Y286H |
possibly damaging |
Het |
| Ttyh2 |
A |
G |
11: 114,601,019 (GRCm39) |
|
probably benign |
Het |
| Zbtb21 |
C |
T |
16: 97,753,827 (GRCm39) |
C180Y |
probably damaging |
Het |
| Zfp746 |
T |
C |
6: 48,041,833 (GRCm39) |
T298A |
probably damaging |
Het |
|
| Other mutations in Adamts16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01024:Adamts16
|
APN |
13 |
70,943,603 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01338:Adamts16
|
APN |
13 |
70,984,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Adamts16
|
APN |
13 |
70,941,260 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01804:Adamts16
|
APN |
13 |
70,949,080 (GRCm39) |
nonsense |
probably null |
|
|
IGL01874:Adamts16
|
APN |
13 |
70,916,823 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01984:Adamts16
|
APN |
13 |
70,935,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02305:Adamts16
|
APN |
13 |
70,921,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02350:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02357:Adamts16
|
APN |
13 |
70,886,704 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02429:Adamts16
|
APN |
13 |
70,935,289 (GRCm39) |
splice site |
probably benign |
|
|
IGL02450:Adamts16
|
APN |
13 |
70,984,419 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02807:Adamts16
|
APN |
13 |
70,886,897 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03356:Adamts16
|
APN |
13 |
70,901,410 (GRCm39) |
missense |
probably benign |
0.00 |
|
swap
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
switcheroo
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0046:Adamts16
|
UTSW |
13 |
70,911,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0201:Adamts16
|
UTSW |
13 |
70,927,763 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0326:Adamts16
|
UTSW |
13 |
70,927,730 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0336:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R0369:Adamts16
|
UTSW |
13 |
70,927,671 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0422:Adamts16
|
UTSW |
13 |
70,887,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0507:Adamts16
|
UTSW |
13 |
70,916,766 (GRCm39) |
missense |
probably benign |
|
|
R0524:Adamts16
|
UTSW |
13 |
70,949,013 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0590:Adamts16
|
UTSW |
13 |
70,949,073 (GRCm39) |
missense |
probably benign |
|
|
R0787:Adamts16
|
UTSW |
13 |
70,886,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0826:Adamts16
|
UTSW |
13 |
70,916,811 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0920:Adamts16
|
UTSW |
13 |
70,911,680 (GRCm39) |
splice site |
probably benign |
|
|
R1027:Adamts16
|
UTSW |
13 |
70,915,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1462:Adamts16
|
UTSW |
13 |
70,984,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1535:Adamts16
|
UTSW |
13 |
70,939,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1617:Adamts16
|
UTSW |
13 |
70,946,154 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1700:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1734:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1736:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1737:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1738:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R1746:Adamts16
|
UTSW |
13 |
70,927,717 (GRCm39) |
splice site |
probably null |
|
|
R1869:Adamts16
|
UTSW |
13 |
70,883,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1944:Adamts16
|
UTSW |
13 |
70,940,005 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1997:Adamts16
|
UTSW |
13 |
70,901,386 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2018:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2135:Adamts16
|
UTSW |
13 |
70,949,126 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2219:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R2228:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R3410:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3411:Adamts16
|
UTSW |
13 |
70,901,345 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3842:Adamts16
|
UTSW |
13 |
70,887,010 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4117:Adamts16
|
UTSW |
13 |
70,916,111 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4435:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4436:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4526:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4552:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4555:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4556:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4557:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4579:Adamts16
|
UTSW |
13 |
70,927,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4639:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4640:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4641:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4642:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R4672:Adamts16
|
UTSW |
13 |
70,927,637 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R5350:Adamts16
|
UTSW |
13 |
70,901,315 (GRCm39) |
nonsense |
probably null |
|
|
R5464:Adamts16
|
UTSW |
13 |
70,909,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5613:Adamts16
|
UTSW |
13 |
70,878,253 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5667:Adamts16
|
UTSW |
13 |
70,984,494 (GRCm39) |
nonsense |
probably null |
|
|
R5735:Adamts16
|
UTSW |
13 |
70,984,337 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5762:Adamts16
|
UTSW |
13 |
70,886,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5907:Adamts16
|
UTSW |
13 |
70,877,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6169:Adamts16
|
UTSW |
13 |
70,918,393 (GRCm39) |
nonsense |
probably null |
|
|
R6351:Adamts16
|
UTSW |
13 |
70,984,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6665:Adamts16
|
UTSW |
13 |
70,927,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6913:Adamts16
|
UTSW |
13 |
70,877,017 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6982:Adamts16
|
UTSW |
13 |
70,916,639 (GRCm39) |
splice site |
probably null |
|
|
R6996:Adamts16
|
UTSW |
13 |
70,946,157 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7313:Adamts16
|
UTSW |
13 |
70,921,074 (GRCm39) |
nonsense |
probably null |
|
|
R7356:Adamts16
|
UTSW |
13 |
70,984,399 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7509:Adamts16
|
UTSW |
13 |
70,935,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7595:Adamts16
|
UTSW |
13 |
70,878,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Adamts16
|
UTSW |
13 |
70,984,265 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7968:Adamts16
|
UTSW |
13 |
70,886,701 (GRCm39) |
missense |
probably benign |
|
|
R8231:Adamts16
|
UTSW |
13 |
70,925,599 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8232:Adamts16
|
UTSW |
13 |
70,941,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8470:Adamts16
|
UTSW |
13 |
70,984,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Adamts16
|
UTSW |
13 |
70,886,794 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8772:Adamts16
|
UTSW |
13 |
70,984,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Adamts16
|
UTSW |
13 |
70,941,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8921:Adamts16
|
UTSW |
13 |
70,939,910 (GRCm39) |
splice site |
probably benign |
|
|
R8973:Adamts16
|
UTSW |
13 |
70,886,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9132:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9149:Adamts16
|
UTSW |
13 |
70,883,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9159:Adamts16
|
UTSW |
13 |
70,901,408 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9312:Adamts16
|
UTSW |
13 |
70,949,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Adamts16
|
UTSW |
13 |
70,949,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adamts16
|
UTSW |
13 |
70,909,892 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGCCCAAGGCTTGATAAAGGCTAC -3'
(R):5'- GCTCTCTTATGCAGTGCTCAAGGAC -3'
Sequencing Primer
(F):5'- GGCTTGATAAAGGCTACCGATATTC -3'
(R):5'- CAGTGCTCAAGGACCTGTG -3'
|
| Posted On |
2013-09-03 |
Incidental Mutation