Incidental Mutation 'R0755:Pcdh7'
| ID |
70406 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdh7
|
| Ensembl Gene |
ENSMUSG00000029108 |
| Gene Name |
protocadherin 7 |
| Synonyms |
BH-protocadherin |
| MMRRC Submission |
038935-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.141)
|
| Stock # |
R0755 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
57875309-58290572 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 57877664 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Asparagine
at position 406
(K406N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066306
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068110]
[ENSMUST00000094783]
[ENSMUST00000191837]
[ENSMUST00000199310]
|
| AlphaFold |
A0A0A6YY83 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000068110
AA Change: K406N
PolyPhen 2
Score 0.864 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000066306
Gene: ENSMUSG00000029108
AA Change: K406N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000094783
AA Change: K406N
|
| SMART Domains |
Protein: ENSMUSP00000092376
Gene: ENSMUSG00000029108
AA Change: K406N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180708
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000191837
AA Change: K406N
PolyPhen 2
Score 0.672 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000142319
Gene: ENSMUSG00000029108
AA Change: K406N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
30 |
N/A |
INTRINSIC |
|
CA
|
48 |
141 |
7.29e-4 |
SMART |
|
CA
|
165 |
306 |
1.13e-18 |
SMART |
|
CA
|
330 |
413 |
2.12e-23 |
SMART |
|
CA
|
445 |
533 |
1.53e-20 |
SMART |
|
CA
|
557 |
637 |
1.36e-26 |
SMART |
|
CA
|
661 |
740 |
2.38e-26 |
SMART |
|
CA
|
766 |
847 |
2.01e-15 |
SMART |
|
transmembrane domain
|
878 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
1088 |
1099 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192048
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000192287
AA Change: K66N
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000193156
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200266
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199310
|
| SMART Domains |
Protein: ENSMUSP00000143387
Gene: ENSMUSG00000029108
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Protocadherin
|
1 |
79 |
5.1e-40 |
PFAM |
|
low complexity region
|
112 |
123 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195156
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 93.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A730061H03Rik |
A |
T |
14: 55,797,638 (GRCm39) |
|
probably benign |
Het |
| Acin1 |
A |
G |
14: 54,889,292 (GRCm39) |
M1T |
probably null |
Het |
| Akp3 |
G |
A |
1: 87,055,593 (GRCm39) |
G547R |
unknown |
Het |
| Aldh1a1 |
A |
G |
19: 20,595,358 (GRCm39) |
M96V |
probably benign |
Het |
| Ankfn1 |
T |
A |
11: 89,282,913 (GRCm39) |
M245L |
probably benign |
Het |
| Arhgap19 |
T |
C |
19: 41,769,614 (GRCm39) |
K54E |
probably damaging |
Het |
| Atp1a2 |
T |
C |
1: 172,116,948 (GRCm39) |
Q223R |
probably benign |
Het |
| Atp8a2 |
C |
T |
14: 60,247,330 (GRCm39) |
V557I |
possibly damaging |
Het |
| AU041133 |
A |
T |
10: 81,986,724 (GRCm39) |
K126* |
probably null |
Het |
| Axin1 |
T |
A |
17: 26,401,480 (GRCm39) |
Y351N |
possibly damaging |
Het |
| Baiap2l1 |
T |
C |
5: 144,221,367 (GRCm39) |
K176E |
probably damaging |
Het |
| Baz2a |
C |
T |
10: 127,955,560 (GRCm39) |
T848I |
possibly damaging |
Het |
| Bbs2 |
A |
C |
8: 94,808,708 (GRCm39) |
V333G |
probably benign |
Het |
| BC051019 |
G |
A |
7: 109,315,302 (GRCm39) |
Q318* |
probably null |
Het |
| Bltp1 |
T |
C |
3: 37,000,513 (GRCm39) |
S1231P |
probably damaging |
Het |
| Cdc37 |
C |
T |
9: 21,051,160 (GRCm39) |
D362N |
probably damaging |
Het |
| Cep170 |
A |
T |
1: 176,583,319 (GRCm39) |
V1020E |
probably damaging |
Het |
| Chrm4 |
T |
C |
2: 91,758,747 (GRCm39) |
V385A |
probably benign |
Het |
| Cntrl |
G |
A |
2: 35,035,151 (GRCm39) |
S373N |
probably damaging |
Het |
| Col23a1 |
G |
A |
11: 51,467,706 (GRCm39) |
G19D |
probably damaging |
Het |
| Cyb5r4 |
G |
T |
9: 86,911,625 (GRCm39) |
A100S |
probably damaging |
Het |
| Dctn1 |
C |
T |
6: 83,166,059 (GRCm39) |
P115S |
probably damaging |
Het |
| Dhrs2 |
C |
T |
14: 55,472,247 (GRCm39) |
T46M |
probably damaging |
Het |
| Disp2 |
T |
C |
2: 118,620,243 (GRCm39) |
F325S |
probably benign |
Het |
| Dnah11 |
T |
G |
12: 117,918,564 (GRCm39) |
T3456P |
possibly damaging |
Het |
| Dnah11 |
C |
A |
12: 118,162,360 (GRCm39) |
V70F |
probably benign |
Het |
| Duoxa1 |
T |
A |
2: 122,135,161 (GRCm39) |
T195S |
probably benign |
Het |
| Dync2i1 |
T |
C |
12: 116,175,412 (GRCm39) |
I922V |
probably benign |
Het |
| Eif2ak1 |
T |
A |
5: 143,821,742 (GRCm39) |
F353I |
possibly damaging |
Het |
| Esam |
A |
G |
9: 37,447,998 (GRCm39) |
T211A |
probably damaging |
Het |
| Faf1 |
A |
G |
4: 109,819,036 (GRCm39) |
N636S |
probably benign |
Het |
| Fbxo25 |
A |
G |
8: 13,985,219 (GRCm39) |
Y305C |
probably benign |
Het |
| Fchsd1 |
C |
T |
18: 38,101,803 (GRCm39) |
|
probably null |
Het |
| Fdxacb1 |
T |
A |
9: 50,683,025 (GRCm39) |
D329E |
possibly damaging |
Het |
| Gvin2 |
A |
T |
7: 105,545,892 (GRCm39) |
F2387I |
possibly damaging |
Het |
| Hbq1b |
A |
T |
11: 32,237,104 (GRCm39) |
|
probably null |
Het |
| Hmcn2 |
T |
A |
2: 31,343,172 (GRCm39) |
V4566E |
probably damaging |
Het |
| Igkv6-29 |
G |
A |
6: 70,116,053 (GRCm39) |
T5I |
probably benign |
Het |
| Itfg1 |
A |
T |
8: 86,452,834 (GRCm39) |
D511E |
possibly damaging |
Het |
| Jmjd1c |
C |
T |
10: 66,932,378 (GRCm39) |
|
probably benign |
Het |
| Kat6b |
T |
A |
14: 21,687,661 (GRCm39) |
M570K |
probably damaging |
Het |
| Kdm4d |
T |
A |
9: 14,375,591 (GRCm39) |
K89M |
probably damaging |
Het |
| Krt19 |
A |
T |
11: 100,032,965 (GRCm39) |
D194E |
possibly damaging |
Het |
| Lamc1 |
A |
T |
1: 153,123,196 (GRCm39) |
Y665N |
possibly damaging |
Het |
| Lct |
A |
T |
1: 128,221,872 (GRCm39) |
S1556T |
possibly damaging |
Het |
| Macf1 |
A |
G |
4: 123,263,719 (GRCm39) |
L4924P |
probably damaging |
Het |
| Mef2c |
G |
A |
13: 83,804,472 (GRCm39) |
|
probably null |
Het |
| Mff |
G |
A |
1: 82,728,326 (GRCm39) |
|
probably null |
Het |
| Mycbp2 |
A |
T |
14: 103,412,230 (GRCm39) |
L2581Q |
probably damaging |
Het |
| Mylk |
G |
C |
16: 34,699,845 (GRCm39) |
E403Q |
possibly damaging |
Het |
| Nos3 |
T |
A |
5: 24,572,295 (GRCm39) |
L123M |
probably damaging |
Het |
| Ntn5 |
C |
T |
7: 45,335,952 (GRCm39) |
P128S |
probably benign |
Het |
| Nudt9 |
T |
C |
5: 104,212,920 (GRCm39) |
V331A |
probably damaging |
Het |
| Or2y3 |
A |
T |
17: 38,393,085 (GRCm39) |
Y261* |
probably null |
Het |
| Or7g34 |
T |
C |
9: 19,478,415 (GRCm39) |
I88M |
possibly damaging |
Het |
| Pkdrej |
T |
A |
15: 85,700,336 (GRCm39) |
I1867L |
probably benign |
Het |
| Plppr4 |
C |
T |
3: 117,116,319 (GRCm39) |
G455R |
possibly damaging |
Het |
| Pramel11 |
A |
G |
4: 143,624,299 (GRCm39) |
V66A |
probably damaging |
Het |
| Prkag2 |
G |
C |
5: 25,152,629 (GRCm39) |
S158R |
probably benign |
Het |
| Ptprq |
T |
G |
10: 107,418,400 (GRCm39) |
T1659P |
probably benign |
Het |
| Rasl12 |
A |
G |
9: 65,318,241 (GRCm39) |
K202E |
probably benign |
Het |
| Rb1 |
A |
C |
14: 73,434,653 (GRCm39) |
*922G |
probably null |
Het |
| Rsf1 |
C |
T |
7: 97,229,174 (GRCm39) |
P22S |
probably damaging |
Het |
| Scn1a |
T |
G |
2: 66,151,379 (GRCm39) |
T797P |
probably damaging |
Het |
| Sgsm2 |
A |
G |
11: 74,756,323 (GRCm39) |
V342A |
probably damaging |
Het |
| Slc22a7 |
T |
G |
17: 46,749,113 (GRCm39) |
H68P |
possibly damaging |
Het |
| Slc4a2 |
G |
A |
5: 24,640,575 (GRCm39) |
A652T |
probably benign |
Het |
| Slc5a1 |
T |
A |
5: 33,290,733 (GRCm39) |
L106M |
probably benign |
Het |
| Slco1c1 |
C |
T |
6: 141,477,258 (GRCm39) |
P19S |
probably damaging |
Het |
| Snx1 |
A |
G |
9: 66,005,738 (GRCm39) |
F127S |
probably damaging |
Het |
| Snx31 |
A |
T |
15: 36,534,576 (GRCm39) |
I199N |
probably damaging |
Het |
| Snx33 |
T |
C |
9: 56,832,741 (GRCm39) |
I443V |
possibly damaging |
Het |
| Sptbn1 |
A |
G |
11: 30,089,016 (GRCm39) |
F749L |
probably damaging |
Het |
| Stoml3 |
T |
A |
3: 53,405,559 (GRCm39) |
Y53* |
probably null |
Het |
| Stxbp2 |
A |
G |
8: 3,692,019 (GRCm39) |
T554A |
probably benign |
Het |
| Tal1 |
T |
C |
4: 114,925,573 (GRCm39) |
I214T |
probably damaging |
Het |
| Tas2r140 |
T |
A |
6: 40,468,344 (GRCm39) |
I58N |
probably damaging |
Het |
| Thap1 |
A |
G |
8: 26,648,501 (GRCm39) |
Y8C |
probably damaging |
Het |
| Thsd7a |
A |
T |
6: 12,555,368 (GRCm39) |
L172Q |
probably damaging |
Het |
| Ube3c |
T |
A |
5: 29,842,740 (GRCm39) |
D735E |
probably damaging |
Het |
| Unc80 |
G |
A |
1: 66,544,082 (GRCm39) |
D402N |
probably damaging |
Het |
| Upf1 |
G |
T |
8: 70,786,779 (GRCm39) |
R902S |
probably benign |
Het |
| Urb1 |
A |
G |
16: 90,570,982 (GRCm39) |
Y1276H |
probably damaging |
Het |
| Urb1 |
A |
T |
16: 90,576,026 (GRCm39) |
F843L |
probably benign |
Het |
| Vmn1r198 |
C |
T |
13: 22,539,402 (GRCm39) |
T296I |
probably benign |
Het |
| Vmn1r33 |
A |
T |
6: 66,588,892 (GRCm39) |
S221T |
probably damaging |
Het |
| Vmn2r103 |
A |
G |
17: 19,993,830 (GRCm39) |
D69G |
probably benign |
Het |
| Vmn2r14 |
T |
G |
5: 109,364,226 (GRCm39) |
L563F |
possibly damaging |
Het |
| Vmn2r60 |
G |
A |
7: 41,844,869 (GRCm39) |
G744D |
probably damaging |
Het |
| Vstm4 |
T |
C |
14: 32,614,601 (GRCm39) |
V181A |
probably damaging |
Het |
| Wdr72 |
G |
A |
9: 74,052,376 (GRCm39) |
V136I |
probably benign |
Het |
| Zfp236 |
T |
A |
18: 82,638,457 (GRCm39) |
N1388Y |
probably damaging |
Het |
| Zfp53 |
T |
A |
17: 21,728,839 (GRCm39) |
F291I |
probably damaging |
Het |
| Zfp944 |
A |
T |
17: 22,558,889 (GRCm39) |
H119Q |
possibly damaging |
Het |
|
| Other mutations in Pcdh7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Pcdh7
|
APN |
5 |
57,878,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00920:Pcdh7
|
APN |
5 |
57,877,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00990:Pcdh7
|
APN |
5 |
57,877,806 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01367:Pcdh7
|
APN |
5 |
58,286,566 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL01388:Pcdh7
|
APN |
5 |
57,877,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01543:Pcdh7
|
APN |
5 |
57,878,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01750:Pcdh7
|
APN |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Pcdh7
|
APN |
5 |
58,286,597 (GRCm39) |
missense |
probably benign |
|
|
IGL02014:Pcdh7
|
APN |
5 |
57,877,045 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02269:Pcdh7
|
APN |
5 |
58,070,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03051:Pcdh7
|
APN |
5 |
58,286,415 (GRCm39) |
missense |
probably damaging |
0.99 |
|
floated
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
proposed
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P0037:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0003:Pcdh7
|
UTSW |
5 |
58,070,590 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0421:Pcdh7
|
UTSW |
5 |
57,877,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0551:Pcdh7
|
UTSW |
5 |
57,879,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Pcdh7
|
UTSW |
5 |
57,877,405 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0732:Pcdh7
|
UTSW |
5 |
57,878,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1080:Pcdh7
|
UTSW |
5 |
57,876,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1381:Pcdh7
|
UTSW |
5 |
57,878,882 (GRCm39) |
nonsense |
probably null |
|
|
R1591:Pcdh7
|
UTSW |
5 |
57,877,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1891:Pcdh7
|
UTSW |
5 |
57,878,217 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2011:Pcdh7
|
UTSW |
5 |
57,876,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Pcdh7
|
UTSW |
5 |
58,286,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:Pcdh7
|
UTSW |
5 |
58,286,458 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R2848:Pcdh7
|
UTSW |
5 |
57,877,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2867:Pcdh7
|
UTSW |
5 |
57,879,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Pcdh7
|
UTSW |
5 |
58,286,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4075:Pcdh7
|
UTSW |
5 |
57,879,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4231:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4236:Pcdh7
|
UTSW |
5 |
57,876,631 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4352:Pcdh7
|
UTSW |
5 |
57,879,361 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4420:Pcdh7
|
UTSW |
5 |
58,286,512 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4449:Pcdh7
|
UTSW |
5 |
57,877,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Pcdh7
|
UTSW |
5 |
57,878,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4686:Pcdh7
|
UTSW |
5 |
58,286,511 (GRCm39) |
missense |
probably benign |
|
|
R4837:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4838:Pcdh7
|
UTSW |
5 |
57,878,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4947:Pcdh7
|
UTSW |
5 |
57,879,258 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5053:Pcdh7
|
UTSW |
5 |
57,878,943 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5068:Pcdh7
|
UTSW |
5 |
57,879,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5117:Pcdh7
|
UTSW |
5 |
57,879,090 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5132:Pcdh7
|
UTSW |
5 |
57,885,463 (GRCm39) |
missense |
probably benign |
|
|
R5248:Pcdh7
|
UTSW |
5 |
58,286,515 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5294:Pcdh7
|
UTSW |
5 |
57,885,453 (GRCm39) |
splice site |
probably null |
|
|
R5420:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5777:Pcdh7
|
UTSW |
5 |
57,876,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5800:Pcdh7
|
UTSW |
5 |
57,879,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5834:Pcdh7
|
UTSW |
5 |
57,878,970 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5870:Pcdh7
|
UTSW |
5 |
57,877,753 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5917:Pcdh7
|
UTSW |
5 |
57,879,097 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6014:Pcdh7
|
UTSW |
5 |
57,878,497 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6193:Pcdh7
|
UTSW |
5 |
57,877,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6240:Pcdh7
|
UTSW |
5 |
57,878,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Pcdh7
|
UTSW |
5 |
58,099,607 (GRCm39) |
splice site |
probably null |
|
|
R6418:Pcdh7
|
UTSW |
5 |
57,879,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6907:Pcdh7
|
UTSW |
5 |
57,876,471 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7058:Pcdh7
|
UTSW |
5 |
57,879,582 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7069:Pcdh7
|
UTSW |
5 |
57,877,126 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7073:Pcdh7
|
UTSW |
5 |
57,878,299 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7463:Pcdh7
|
UTSW |
5 |
57,878,340 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7509:Pcdh7
|
UTSW |
5 |
57,877,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7588:Pcdh7
|
UTSW |
5 |
57,877,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7707:Pcdh7
|
UTSW |
5 |
57,877,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7734:Pcdh7
|
UTSW |
5 |
57,876,976 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7899:Pcdh7
|
UTSW |
5 |
57,877,152 (GRCm39) |
missense |
probably benign |
|
|
R8194:Pcdh7
|
UTSW |
5 |
57,877,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8480:Pcdh7
|
UTSW |
5 |
58,286,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8890:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Pcdh7
|
UTSW |
5 |
57,879,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8990:Pcdh7
|
UTSW |
5 |
57,879,364 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9264:Pcdh7
|
UTSW |
5 |
58,286,663 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9272:Pcdh7
|
UTSW |
5 |
57,878,779 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9294:Pcdh7
|
UTSW |
5 |
57,878,677 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9518:Pcdh7
|
UTSW |
5 |
58,070,513 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9597:Pcdh7
|
UTSW |
5 |
57,877,197 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9642:Pcdh7
|
UTSW |
5 |
57,876,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Pcdh7
|
UTSW |
5 |
57,879,622 (GRCm39) |
critical splice donor site |
probably null |
|
|
X0021:Pcdh7
|
UTSW |
5 |
57,878,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
X0026:Pcdh7
|
UTSW |
5 |
57,876,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Pcdh7
|
UTSW |
5 |
57,877,006 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATGAGGCTGACCTGGCTGAGAAC -3'
(R):5'- AAGCTGGAAAGGAACGTCTCCCAC -3'
Sequencing Primer
(F):5'- CGCCACCGATTTGGATGTAG -3'
(R):5'- TCCCACTACGGTACAGGTGAC -3'
|
| Posted On |
2013-09-30 |
Incidental Mutation