Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01289:Fam136b-ps'

72862

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Fam136b-ps

Ensembl Gene

ENSMUSG00000055416

Gene Name

family with sequence similarity 136, member B, pseudogene

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.153) question?

Stock #

IGL01289

Quality Score

Status

Chromosome

Chromosomal Location

31276637-31277048 bp(+) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to A at 31277010 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000140481 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000044524] [ENSMUST00000068987] [ENSMUST00000185618] [ENSMUST00000186109] [ENSMUST00000186425] [ENSMUST00000186547]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000044524

SMART Domains

Protein: ENSMUSP00000047186
Gene: ENSMUSG00000039168

Domain	Start	End	E-Value	Type
Pfam:DAP	12	102	3.3e-34	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000068987

SMART Domains

Protein: ENSMUSP00000125904
Gene: ENSMUSG00000055416

Domain	Start	End	E-Value	Type
Pfam:DUF842	5	132	2.4e-48	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000185618

SMART Domains

Protein: ENSMUSP00000140568
Gene: ENSMUSG00000039168

Domain	Start	End	E-Value	Type
Pfam:DAP	3	62	4.5e-15	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000186109

Predicted Effect

probably benign
Transcript: ENSMUST00000186425

SMART Domains

Protein: ENSMUSP00000140007
Gene: ENSMUSG00000039168

Domain	Start	End	E-Value	Type
Pfam:DAP	1	79	6.5e-20	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000186547

SMART Domains

Protein: ENSMUSP00000140481
Gene: ENSMUSG00000039168

Domain	Start	End	E-Value	Type
Pfam:DAP	1	79	6.5e-20	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933402N03Rik	T	A	7: 130,740,350 (GRCm39)	M289L	probably benign	Het
Actg2	A	T	6: 83,500,157 (GRCm39)	M38K	probably damaging	Het
Atp8a2	G	A	14: 59,928,910 (GRCm39)	A1048V	probably benign	Het
Cables1	T	C	18: 12,077,621 (GRCm39)	V583A	probably damaging	Het
Ccng2	A	G	5: 93,421,276 (GRCm39)	K262R	probably null	Het
Cfap206	C	A	4: 34,716,469 (GRCm39)	S332I	probably null	Het
Dscam	A	T	16: 96,445,082 (GRCm39)	Y1536*	probably null	Het
Fga	A	G	3: 82,938,552 (GRCm39)	Y309C	possibly damaging	Het
Fgd4	A	T	16: 16,302,167 (GRCm39)	N129K	probably damaging	Het
Gbp8	G	A	5: 105,165,735 (GRCm39)	A306V	probably benign	Het
Hecw1	T	C	13: 14,438,719 (GRCm39)	Y888C	probably damaging	Het
Herc6	G	A	6: 57,575,608 (GRCm39)	G210R	probably damaging	Het
Ints7	G	A	1: 191,347,890 (GRCm39)	R754H	probably benign	Het
Itga1	T	C	13: 115,122,762 (GRCm39)	I731M	possibly damaging	Het
Itpr2	T	A	6: 146,014,033 (GRCm39)	K2588*	probably null	Het
Itpr3	T	A	17: 27,318,739 (GRCm39)	M965K	probably damaging	Het
Kif22	A	G	7: 126,632,645 (GRCm39)	V247A	probably damaging	Het
Lrrc17	T	C	5: 21,765,899 (GRCm39)	F127S	probably damaging	Het
Lrriq4	T	A	3: 30,704,542 (GRCm39)	L190Q	probably damaging	Het
Mcee	T	A	7: 64,050,066 (GRCm39)	F66I	probably damaging	Het
Med23	T	C	10: 24,778,019 (GRCm39)	F789S	probably damaging	Het
Nmd3	T	G	3: 69,631,620 (GRCm39)	S25R	possibly damaging	Het
Npy5r	T	A	8: 67,134,518 (GRCm39)	N92Y	possibly damaging	Het
Or4a69	A	G	2: 89,313,191 (GRCm39)	M96T	probably benign	Het
Rnf224	G	T	2: 25,126,259 (GRCm39)	D31E	possibly damaging	Het
Timd2	T	C	11: 46,570,499 (GRCm39)	E192G	probably benign	Het
Ttll13	T	A	7: 79,910,187 (GRCm39)	C777S	probably benign	Het
Tubgcp3	A	G	8: 12,689,625 (GRCm39)	L547P	probably damaging	Het
Usp47	G	T	7: 111,662,565 (GRCm39)	V236F	probably damaging	Het
Xirp2	A	T	2: 67,343,525 (GRCm39)	N1922I	probably damaging	Het
Zdhhc24	G	T	19: 4,928,850 (GRCm39)	W25L	probably damaging	Het

Other mutations in Fam136b-ps

Allele	Source	Chr	Coord	Type	Predicted Effect
R1080:Fam136b-ps	UTSW	15	31,276,739 (GRCm39)	unclassified	probably benign
R5033:Fam136b-ps	UTSW	15	31,277,043 (GRCm39)	unclassified	probably benign
R5070:Fam136b-ps	UTSW	15	31,276,862 (GRCm39)	unclassified	probably benign
R5110:Fam136b-ps	UTSW	15	31,276,856 (GRCm39)	unclassified	probably benign
R6629:Fam136b-ps	UTSW	15	31,276,962 (GRCm39)	unclassified	probably benign

Posted On

2013-10-07