Incidental Mutation 'IGL01292:Gdpd4'
ID72961
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gdpd4
Ensembl Gene ENSMUSG00000035582
Gene Nameglycerophosphodiester phosphodiesterase domain containing 4
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.081) question?
Stock #IGL01292
Quality Score
Status
Chromosome7
Chromosomal Location97919955-98049663 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 98014954 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000131960 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000041860] [ENSMUST00000170049]
Predicted Effect probably benign
Transcript: ENSMUST00000041860
SMART Domains Protein: ENSMUSP00000036772
Gene: ENSMUSG00000035582

DomainStartEndE-ValueType
transmembrane domain 65 84 N/A INTRINSIC
transmembrane domain 104 135 N/A INTRINSIC
transmembrane domain 148 168 N/A INTRINSIC
transmembrane domain 183 205 N/A INTRINSIC
transmembrane domain 241 263 N/A INTRINSIC
Pfam:GDPD 281 440 1.4e-19 PFAM
transmembrane domain 543 565 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000170049
SMART Domains Protein: ENSMUSP00000131960
Gene: ENSMUSG00000035582

DomainStartEndE-ValueType
transmembrane domain 65 84 N/A INTRINSIC
transmembrane domain 104 135 N/A INTRINSIC
transmembrane domain 148 168 N/A INTRINSIC
transmembrane domain 183 205 N/A INTRINSIC
transmembrane domain 241 263 N/A INTRINSIC
Pfam:GDPD 281 439 3.4e-21 PFAM
transmembrane domain 543 565 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
3425401B19Rik T C 14: 32,660,874 S1045G probably benign Het
Aak1 T C 6: 86,949,538 probably benign Het
Car15 A G 16: 17,835,529 F258S probably damaging Het
Cpd A G 11: 76,846,245 I241T possibly damaging Het
Dchs1 T C 7: 105,760,891 D1758G probably damaging Het
Eogt T A 6: 97,144,027 N75I possibly damaging Het
Eps8l1 T C 7: 4,478,920 probably benign Het
Igbp1b C T 6: 138,657,535 E304K probably benign Het
Ighv1-63 A G 12: 115,495,858 S40P probably damaging Het
Intu T C 3: 40,664,266 V234A probably benign Het
Lrrc6 A T 15: 66,481,233 probably benign Het
Mars A T 10: 127,305,518 I334N probably damaging Het
Morc2a C A 11: 3,688,175 A967D probably damaging Het
Mtrf1l A T 10: 5,814,090 M291K probably benign Het
Muc19 A G 15: 91,894,276 noncoding transcript Het
Myl3 A T 9: 110,767,977 D135V probably damaging Het
Myt1 T A 2: 181,805,012 L537M probably damaging Het
Ndst4 A G 3: 125,438,754 D324G probably damaging Het
Plce1 T A 19: 38,651,785 probably benign Het
Prkab1 A T 5: 116,024,110 F47Y probably damaging Het
Prkag2 C T 5: 25,021,965 S98N probably benign Het
Rasgef1a T A 6: 118,080,383 V15D possibly damaging Het
Scgb1b19 T A 7: 33,287,626 C67* probably null Het
Slc25a15 T C 8: 22,390,036 D31G possibly damaging Het
Slc4a11 C T 2: 130,690,832 probably null Het
Snx15 A T 19: 6,119,885 M331K probably benign Het
Tsks T C 7: 44,952,558 Y224H probably damaging Het
Ufd1 T C 16: 18,821,114 S123P probably damaging Het
Xpnpep3 T G 15: 81,427,498 V135G probably damaging Het
Other mutations in Gdpd4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00517:Gdpd4 APN 7 98004271 missense probably damaging 1.00
IGL01317:Gdpd4 APN 7 97998258 missense possibly damaging 0.74
IGL02678:Gdpd4 APN 7 97974377 splice site probably benign
IGL02822:Gdpd4 APN 7 97971924 missense possibly damaging 0.82
IGL02987:Gdpd4 APN 7 97961551 splice site probably benign
R0022:Gdpd4 UTSW 7 97982875 missense probably damaging 1.00
R0331:Gdpd4 UTSW 7 97973008 missense probably benign 0.11
R0882:Gdpd4 UTSW 7 97966298 missense probably damaging 1.00
R1425:Gdpd4 UTSW 7 97974012 missense probably benign 0.03
R1469:Gdpd4 UTSW 7 97974466 splice site probably null
R1469:Gdpd4 UTSW 7 97974466 splice site probably null
R1870:Gdpd4 UTSW 7 97972955 missense probably benign 0.00
R4747:Gdpd4 UTSW 7 97961633 missense possibly damaging 0.80
R5017:Gdpd4 UTSW 7 98004275 nonsense probably null
R5208:Gdpd4 UTSW 7 98014911 missense probably benign 0.11
R5290:Gdpd4 UTSW 7 97966336 missense possibly damaging 0.94
R5398:Gdpd4 UTSW 7 97971978 missense probably benign 0.00
R5605:Gdpd4 UTSW 7 98006300 missense probably benign 0.41
R5715:Gdpd4 UTSW 7 97961597 missense probably benign 0.00
R5990:Gdpd4 UTSW 7 98040930 missense probably benign 0.00
R6269:Gdpd4 UTSW 7 97974462 missense probably damaging 1.00
R6314:Gdpd4 UTSW 7 97973953 missense probably damaging 0.98
R6817:Gdpd4 UTSW 7 97957830 missense probably benign 0.00
R6884:Gdpd4 UTSW 7 97972175 missense probably damaging 1.00
R7054:Gdpd4 UTSW 7 97973929 missense probably damaging 0.99
Z1088:Gdpd4 UTSW 7 97966309 missense probably damaging 0.99
Posted On2013-10-07