Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01310:Nrxn1'

73665

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Nrxn1

Ensembl Gene

ENSMUSG00000024109

Gene Name

neurexin I

Synonyms

alpha-latrotoxin receptor (calcium-dependent), 1700062G21Rik, neurexin I alpha, neurexin I alpha, 9330127H16Rik, neurexin I beta, neurexin I beta, A230068P09Rik, neurexin I alpha, neurexin I beta

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01310

Quality Score

Status

Chromosome

Chromosomal Location

90341059-91400499 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to G at 90366902 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000133724 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000054059] [ENSMUST00000072671] [ENSMUST00000159778] [ENSMUST00000160800] [ENSMUST00000160844] [ENSMUST00000161402] [ENSMUST00000172466] [ENSMUST00000174331] [ENSMUST00000173222] [ENSMUST00000197268] [ENSMUST00000174337] [ENSMUST00000173917] [ENSMUST00000197104]

AlphaFold

Q9CS84

Predicted Effect

probably null
Transcript: ENSMUST00000054059

SMART Domains

Protein: ENSMUSP00000057294
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
low complexity region	9	23	N/A	INTRINSIC
LamG	50	192	2.29e-31	SMART
EGF	216	256	4.26e0	SMART
LamG	304	438	2.3e-36	SMART
LamG	492	644	2.74e-43	SMART
EGF	671	705	1.58e-3	SMART
LamG	730	869	7.27e-25	SMART
LamG	917	1053	8.46e-35	SMART
EGF	1078	1112	1.87e1	SMART
LamG	1140	1297	7.74e-20	SMART
low complexity region	1324	1355	N/A	INTRINSIC
low complexity region	1426	1441	N/A	INTRINSIC
4.1m	1444	1462	1.19e-6	SMART
low complexity region	1481	1493	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000072671

SMART Domains

Protein: ENSMUSP00000072458
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
low complexity region	9	23	N/A	INTRINSIC
LamG	50	192	2.29e-31	SMART
EGF	216	256	4.26e0	SMART
LamG	304	438	2.3e-36	SMART
LamG	492	644	2.74e-43	SMART
EGF	671	705	1.58e-3	SMART
LamG	730	869	7.27e-25	SMART
LamG	917	1053	8.46e-35	SMART
EGF	1078	1112	1.87e1	SMART
LamG	1140	1297	7.74e-20	SMART
low complexity region	1324	1355	N/A	INTRINSIC
low complexity region	1423	1438	N/A	INTRINSIC
4.1m	1441	1459	1.19e-6	SMART
low complexity region	1478	1490	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000159778

SMART Domains

Protein: ENSMUSP00000125561
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
low complexity region	9	23	N/A	INTRINSIC
LamG	50	192	2.29e-31	SMART
EGF	216	256	4.26e0	SMART
LamG	284	418	2.3e-36	SMART
LamG	472	624	2.74e-43	SMART
EGF	651	685	1.58e-3	SMART
LamG	710	849	7.27e-25	SMART
LamG	897	1033	8.46e-35	SMART
EGF	1058	1092	1.87e1	SMART
LamG	1120	1277	7.74e-20	SMART
low complexity region	1304	1335	N/A	INTRINSIC
low complexity region	1403	1418	N/A	INTRINSIC
4.1m	1421	1439	1.19e-6	SMART
low complexity region	1458	1470	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000160800

SMART Domains

Protein: ENSMUSP00000124561
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
low complexity region	9	23	N/A	INTRINSIC
LamG	50	192	2.29e-31	SMART
EGF	216	256	4.26e0	SMART
LamG	300	434	2.3e-36	SMART
LamG	488	640	2.74e-43	SMART
EGF	667	701	1.58e-3	SMART
LamG	726	865	7.27e-25	SMART
LamG	913	1049	8.46e-35	SMART
EGF	1074	1108	1.87e1	SMART
LamG	1136	1293	7.74e-20	SMART
low complexity region	1320	1351	N/A	INTRINSIC
low complexity region	1422	1437	N/A	INTRINSIC
4.1m	1440	1458	1.19e-6	SMART
low complexity region	1477	1489	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000160844

SMART Domains

Protein: ENSMUSP00000125407
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
low complexity region	9	23	N/A	INTRINSIC
LamG	50	192	2.29e-31	SMART
EGF	216	256	4.26e0	SMART
LamG	304	446	1.24e-32	SMART
LamG	500	652	2.74e-43	SMART
EGF	679	713	1.58e-3	SMART
LamG	738	877	7.27e-25	SMART
LamG	925	1061	8.46e-35	SMART
EGF	1086	1120	1.87e1	SMART
LamG	1148	1305	7.74e-20	SMART
low complexity region	1332	1363	N/A	INTRINSIC
low complexity region	1434	1449	N/A	INTRINSIC
4.1m	1452	1470	1.19e-6	SMART
low complexity region	1489	1501	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000161402

SMART Domains

Protein: ENSMUSP00000124116
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
low complexity region	9	23	N/A	INTRINSIC
LamG	50	192	2.29e-31	SMART
EGF	216	256	4.26e0	SMART
LamG	304	453	3.46e-31	SMART
LamG	507	659	2.74e-43	SMART
EGF	686	720	1.58e-3	SMART
LamG	745	884	7.27e-25	SMART
LamG	932	1068	8.46e-35	SMART
EGF	1093	1127	1.87e1	SMART
LamG	1155	1312	7.74e-20	SMART
low complexity region	1339	1370	N/A	INTRINSIC
low complexity region	1441	1456	N/A	INTRINSIC
4.1m	1459	1477	1.19e-6	SMART
low complexity region	1496	1508	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000172466

SMART Domains

Protein: ENSMUSP00000134402
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
transmembrane domain	27	49	N/A	INTRINSIC
LamG	109	266	7.74e-20	SMART
low complexity region	293	324	N/A	INTRINSIC
low complexity region	395	410	N/A	INTRINSIC
4.1m	413	431	1.19e-6	SMART
low complexity region	450	462	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000174331

SMART Domains

Protein: ENSMUSP00000133491
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
signal peptide	1	30	N/A	INTRINSIC
LamG	50	192	2.29e-31	SMART
EGF	216	256	4.26e0	SMART
LamG	304	446	1.24e-32	SMART
LamG	500	652	2.74e-43	SMART
EGF	679	713	1.58e-3	SMART
LamG	738	877	7.27e-25	SMART
LamG	925	1061	8.46e-35	SMART
EGF	1086	1120	1.87e1	SMART
LamG	1148	1275	3.29e-23	SMART
low complexity region	1302	1333	N/A	INTRINSIC
low complexity region	1404	1419	N/A	INTRINSIC
4.1m	1422	1440	1.19e-6	SMART
low complexity region	1459	1471	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000173222

Predicted Effect

probably benign
Transcript: ENSMUST00000197268

SMART Domains

Protein: ENSMUSP00000142815
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
low complexity region	66	81	N/A	INTRINSIC
4.1m	84	102	1.19e-6	SMART
low complexity region	121	133	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000174337

SMART Domains

Protein: ENSMUSP00000133724
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
transmembrane domain	27	49	N/A	INTRINSIC
LamG	109	236	3.29e-23	SMART
low complexity region	263	294	N/A	INTRINSIC
low complexity region	365	380	N/A	INTRINSIC
4.1m	383	401	1.19e-6	SMART
low complexity region	420	432	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000173917

SMART Domains

Protein: ENSMUSP00000133389
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
low complexity region	66	81	N/A	INTRINSIC
4.1m	84	102	1.19e-6	SMART
low complexity region	121	133	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000197104

SMART Domains

Protein: ENSMUSP00000142621
Gene: ENSMUSG00000024109

Domain	Start	End	E-Value	Type
Pfam:Laminin_G_2	1	69	3.2e-12	PFAM
low complexity region	96	127	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are synaptic transmembrane receptors that bind endogenous ligands that include neuroligins, dystroglycan, and neurexophilins. Neurexin complexes are required for efficient neurotransmission and are involved in synaptogenesis. In vertebrates, alternate promoter usage results in multiple isoform classes, of which the alpha and beta classes are the best characterized. In humans, allelic variants in this gene are associated with Pitt-Hopkins-like syndrome-2, while deletions have been associated with autism and schizophrenia. Mouse knockouts display decreased spontaneous and evoked vesicle release resulting in impaired synaptic transmission. In addition, knockout mice show altered social approach, reduced social investigation, reduced locomotor activity, and in males, increased aggression. Alternative splicing and promoter usage result in multiple transcript variants. [provided by RefSeq, Nov 2016]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced Ca(2+)-dependent binding of alpha-latrotoxin to brain membranes. Isolated synaptosomes display only a small reduction in alpha-latrotoxin -triggered glutamate release in the absence of Ca(2+) but show a major decrease in the presence of Ca(2+). [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930431F12Rik	A	T	5: 45,125,156 (GRCm39)		noncoding transcript	Het
Abca12	A	T	1: 71,323,315 (GRCm39)	I1589N	probably benign	Het
Abca8a	T	G	11: 109,950,801 (GRCm39)	D888A	probably benign	Het
Adam5	C	T	8: 25,232,150 (GRCm39)		probably benign	Het
Amer1	A	T	X: 94,470,716 (GRCm39)	N467K	probably benign	Het
Atp6v0a2	A	G	5: 124,783,968 (GRCm39)	D272G	probably damaging	Het
Cacna1b	A	T	2: 24,575,794 (GRCm39)	N751K	probably damaging	Het
Cfi	T	A	3: 129,652,080 (GRCm39)	N250K	probably damaging	Het
Cndp2	G	T	18: 84,689,002 (GRCm39)	P260Q	possibly damaging	Het
Cnnm3	A	G	1: 36,551,956 (GRCm39)	D322G	probably benign	Het
Crybg1	A	T	10: 43,851,054 (GRCm39)	S1606T	possibly damaging	Het
Crybg1	A	G	10: 43,879,596 (GRCm39)	S531P	probably damaging	Het
Espnl	A	T	1: 91,268,333 (GRCm39)	K320*	probably null	Het
Glt1d1	A	G	5: 127,709,384 (GRCm39)	T13A	possibly damaging	Het
Gpam	C	T	19: 55,066,764 (GRCm39)	A584T	possibly damaging	Het
Gpr19	A	G	6: 134,846,705 (GRCm39)	I289T	probably damaging	Het
Grm8	T	C	6: 27,363,800 (GRCm39)	I572V	probably damaging	Het
Gtpbp4	A	T	13: 9,027,308 (GRCm39)	N502K	probably benign	Het
Herpud2	T	C	9: 25,062,247 (GRCm39)	M6V	probably benign	Het
Igdcc3	T	C	9: 65,085,724 (GRCm39)	V263A	probably damaging	Het
Il33	G	A	19: 29,930,156 (GRCm39)	A65T	probably benign	Het
Itga9	T	A	9: 118,598,227 (GRCm39)	M1K	probably null	Het
Izumo3	T	C	4: 92,035,217 (GRCm39)		probably benign	Het
Kdr	G	A	5: 76,110,261 (GRCm39)	P909S	probably damaging	Het
Kirrel1	C	T	3: 86,997,182 (GRCm39)	E262K	probably benign	Het
Krt25	T	A	11: 99,208,996 (GRCm39)	Q278L	probably benign	Het
Lgi2	G	T	5: 52,711,807 (GRCm39)	P195Q	probably benign	Het
Lpcat3	T	C	6: 124,676,301 (GRCm39)	F120S	possibly damaging	Het
Nalcn	C	T	14: 123,554,661 (GRCm39)	R910Q	probably benign	Het
Nuf2	A	T	1: 169,326,431 (GRCm39)	V440E	probably benign	Het
Or10ag60	T	A	2: 87,437,852 (GRCm39)	I40N	possibly damaging	Het
Or4f14	C	T	2: 111,742,652 (GRCm39)	V208M	probably benign	Het
Or51ah3	C	T	7: 103,210,008 (GRCm39)	S108F	probably benign	Het
Or6c205	T	C	10: 129,086,865 (GRCm39)	I154T	possibly damaging	Het
Pfpl	A	G	19: 12,405,974 (GRCm39)	D75G	probably damaging	Het
Pgm5	A	G	19: 24,812,130 (GRCm39)	V134A	possibly damaging	Het
Prkch	A	G	12: 73,805,787 (GRCm39)	I521V	possibly damaging	Het
Rps6kc1	T	A	1: 190,515,822 (GRCm39)	E968V	probably benign	Het
Slc25a30	T	C	14: 76,007,037 (GRCm39)	Y153C	probably damaging	Het
Smtnl2	T	A	11: 72,292,171 (GRCm39)		probably null	Het
Spmip4	C	A	6: 50,551,175 (GRCm39)	V425L	probably benign	Het
Tbc1d14	T	A	5: 36,700,544 (GRCm39)	K275*	probably null	Het
Tnc	T	C	4: 63,931,314 (GRCm39)	T799A	probably benign	Het
Trdn	A	T	10: 33,181,094 (GRCm39)		probably benign	Het
Ttn	T	C	2: 76,706,879 (GRCm39)		probably benign	Het
Uaca	T	C	9: 60,779,507 (GRCm39)	M1296T	probably benign	Het
Ubash3a	A	C	17: 31,434,116 (GRCm39)	I154L	probably benign	Het
Vmn2r4	T	A	3: 64,317,200 (GRCm39)		probably null	Het
Xpc	T	C	6: 91,467,089 (GRCm39)	K915E	probably benign	Het
Zfp318	T	C	17: 46,724,153 (GRCm39)	I2052T	possibly damaging	Het

Other mutations in Nrxn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01644:Nrxn1	APN	17	90,928,301 (GRCm39)	missense	possibly damaging	0.94
IGL01820:Nrxn1	APN	17	90,950,531 (GRCm39)	missense	probably damaging	0.98
IGL01902:Nrxn1	APN	17	91,395,919 (GRCm39)	splice site	probably null
IGL02079:Nrxn1	APN	17	90,950,511 (GRCm39)	missense	probably damaging	0.99
IGL02089:Nrxn1	APN	17	91,395,829 (GRCm39)	missense	probably benign	0.01
IGL02133:Nrxn1	APN	17	90,950,671 (GRCm39)	missense	probably damaging	1.00
IGL02179:Nrxn1	APN	17	90,937,511 (GRCm39)	missense	probably damaging	0.99
IGL02199:Nrxn1	APN	17	90,344,686 (GRCm39)	missense	probably damaging	1.00
IGL02262:Nrxn1	APN	17	91,011,636 (GRCm39)	missense	probably damaging	1.00
IGL02941:Nrxn1	APN	17	90,515,811 (GRCm39)	missense	probably damaging	1.00
PIT4449001:Nrxn1	UTSW	17	90,905,007 (GRCm39)	missense	probably damaging	1.00
PIT4791001:Nrxn1	UTSW	17	90,762,931 (GRCm39)	intron	probably benign
R0123:Nrxn1	UTSW	17	91,302,915 (GRCm39)	splice site	probably null
R0212:Nrxn1	UTSW	17	90,670,186 (GRCm39)	unclassified	probably benign
R0277:Nrxn1	UTSW	17	91,008,170 (GRCm39)	critical splice donor site	probably null
R0323:Nrxn1	UTSW	17	91,008,170 (GRCm39)	critical splice donor site	probably null
R0384:Nrxn1	UTSW	17	90,515,775 (GRCm39)	missense	probably damaging	1.00
R0395:Nrxn1	UTSW	17	91,395,742 (GRCm39)	missense	possibly damaging	0.90
R0606:Nrxn1	UTSW	17	90,872,801 (GRCm39)	missense	probably damaging	1.00
R0616:Nrxn1	UTSW	17	90,670,285 (GRCm39)	missense	probably damaging	1.00
R0624:Nrxn1	UTSW	17	91,396,117 (GRCm39)	missense	unknown
R0633:Nrxn1	UTSW	17	91,011,609 (GRCm39)	missense	probably damaging	1.00
R0927:Nrxn1	UTSW	17	90,344,758 (GRCm39)	missense	probably damaging	1.00
R1035:Nrxn1	UTSW	17	90,471,302 (GRCm39)	missense	probably damaging	0.96
R1221:Nrxn1	UTSW	17	90,950,722 (GRCm39)	missense	probably damaging	0.97
R1403:Nrxn1	UTSW	17	90,950,481 (GRCm39)	missense	probably benign	0.11
R1403:Nrxn1	UTSW	17	90,950,481 (GRCm39)	missense	probably benign	0.11
R1691:Nrxn1	UTSW	17	90,469,717 (GRCm39)	missense	probably damaging	0.98
R1703:Nrxn1	UTSW	17	90,515,845 (GRCm39)	missense	probably damaging	1.00
R1709:Nrxn1	UTSW	17	90,344,615 (GRCm39)	missense	probably damaging	1.00
R1721:Nrxn1	UTSW	17	90,469,832 (GRCm39)	missense	probably damaging	1.00
R1792:Nrxn1	UTSW	17	90,896,252 (GRCm39)	missense	probably damaging	0.96
R1980:Nrxn1	UTSW	17	91,395,746 (GRCm39)	missense	probably benign	0.01
R2116:Nrxn1	UTSW	17	91,011,705 (GRCm39)	missense	probably damaging	1.00
R2117:Nrxn1	UTSW	17	91,011,705 (GRCm39)	missense	probably damaging	1.00
R2162:Nrxn1	UTSW	17	90,469,859 (GRCm39)	missense	probably damaging	1.00
R3119:Nrxn1	UTSW	17	90,904,947 (GRCm39)	nonsense	probably null
R3409:Nrxn1	UTSW	17	90,515,795 (GRCm39)	missense	probably damaging	1.00
R3683:Nrxn1	UTSW	17	90,930,880 (GRCm39)	missense	probably damaging	1.00
R3885:Nrxn1	UTSW	17	90,930,899 (GRCm39)	missense	probably damaging	1.00
R3939:Nrxn1	UTSW	17	90,515,849 (GRCm39)	missense	probably damaging	1.00
R4475:Nrxn1	UTSW	17	91,009,410 (GRCm39)	missense	probably damaging	0.98
R4640:Nrxn1	UTSW	17	90,868,196 (GRCm39)	missense	probably damaging	1.00
R4678:Nrxn1	UTSW	17	90,930,850 (GRCm39)	missense	probably damaging	1.00
R4690:Nrxn1	UTSW	17	90,344,509 (GRCm39)	missense	probably damaging	1.00
R4790:Nrxn1	UTSW	17	90,762,477 (GRCm39)	missense	possibly damaging	0.86
R4877:Nrxn1	UTSW	17	91,395,605 (GRCm39)	missense	probably benign	0.33
R4989:Nrxn1	UTSW	17	90,928,274 (GRCm39)	intron	probably benign
R5204:Nrxn1	UTSW	17	90,469,792 (GRCm39)	missense	probably damaging	1.00
R5205:Nrxn1	UTSW	17	90,471,302 (GRCm39)	missense	probably damaging	0.96
R5239:Nrxn1	UTSW	17	91,011,537 (GRCm39)	missense	probably damaging	1.00
R5250:Nrxn1	UTSW	17	90,842,869 (GRCm39)	intron	probably benign
R5473:Nrxn1	UTSW	17	90,897,520 (GRCm39)	missense	probably damaging	1.00
R5629:Nrxn1	UTSW	17	90,897,460 (GRCm39)	missense	possibly damaging	0.75
R5743:Nrxn1	UTSW	17	90,950,652 (GRCm39)	missense	probably damaging	1.00
R5910:Nrxn1	UTSW	17	91,011,746 (GRCm39)	nonsense	probably null
R5961:Nrxn1	UTSW	17	90,762,371 (GRCm39)	missense	probably damaging	0.99
R5979:Nrxn1	UTSW	17	91,395,631 (GRCm39)	missense	possibly damaging	0.54
R5992:Nrxn1	UTSW	17	90,930,935 (GRCm39)	missense	probably benign	0.01
R6024:Nrxn1	UTSW	17	90,897,526 (GRCm39)	missense	possibly damaging	0.88
R6031:Nrxn1	UTSW	17	90,896,218 (GRCm39)	missense	probably damaging	1.00
R6031:Nrxn1	UTSW	17	90,896,218 (GRCm39)	missense	probably damaging	1.00
R6185:Nrxn1	UTSW	17	90,344,564 (GRCm39)	missense	probably damaging	1.00
R6220:Nrxn1	UTSW	17	91,395,904 (GRCm39)	missense	probably benign	0.14
R6306:Nrxn1	UTSW	17	90,872,874 (GRCm39)	missense	possibly damaging	0.55
R6621:Nrxn1	UTSW	17	90,469,610 (GRCm39)	missense	probably damaging	1.00
R6669:Nrxn1	UTSW	17	90,366,991 (GRCm39)	missense	probably damaging	0.98
R6770:Nrxn1	UTSW	17	90,344,607 (GRCm39)	missense	probably damaging	1.00
R6798:Nrxn1	UTSW	17	90,937,378 (GRCm39)	missense	probably damaging	1.00
R6923:Nrxn1	UTSW	17	91,395,661 (GRCm39)	missense	probably benign	0.06
R7140:Nrxn1	UTSW	17	91,396,192 (GRCm39)	start gained	probably benign
R7374:Nrxn1	UTSW	17	90,896,097 (GRCm39)	critical splice donor site	probably null
R7564:Nrxn1	UTSW	17	90,670,334 (GRCm39)	missense	possibly damaging	0.64
R7570:Nrxn1	UTSW	17	90,469,807 (GRCm39)	missense	probably benign	0.35
R7800:Nrxn1	UTSW	17	91,396,635 (GRCm39)	unclassified	probably benign
R7828:Nrxn1	UTSW	17	90,366,979 (GRCm39)	missense	probably damaging	0.99
R7974:Nrxn1	UTSW	17	91,008,207 (GRCm39)	missense	probably damaging	1.00
R8001:Nrxn1	UTSW	17	91,395,964 (GRCm39)	missense	possibly damaging	0.49
R8189:Nrxn1	UTSW	17	91,011,637 (GRCm39)	missense	probably damaging	0.96
R8258:Nrxn1	UTSW	17	90,471,249 (GRCm39)	missense	probably damaging	0.99
R8259:Nrxn1	UTSW	17	90,471,249 (GRCm39)	missense	probably damaging	0.99
R8298:Nrxn1	UTSW	17	91,011,597 (GRCm39)	missense	probably damaging	1.00
R8801:Nrxn1	UTSW	17	91,009,393 (GRCm39)	critical splice donor site	probably benign
R8814:Nrxn1	UTSW	17	90,937,529 (GRCm39)	missense	probably damaging	1.00
R8873:Nrxn1	UTSW	17	90,872,821 (GRCm39)	nonsense	probably null
R8954:Nrxn1	UTSW	17	90,897,615 (GRCm39)	missense	probably damaging	1.00
R9086:Nrxn1	UTSW	17	90,469,792 (GRCm39)	missense	probably damaging	1.00
R9110:Nrxn1	UTSW	17	90,869,233 (GRCm39)	nonsense	probably null
R9498:Nrxn1	UTSW	17	90,897,397 (GRCm39)	missense	probably damaging	1.00
R9499:Nrxn1	UTSW	17	90,937,450 (GRCm39)	missense	probably damaging	1.00
R9552:Nrxn1	UTSW	17	90,937,450 (GRCm39)	missense	probably damaging	1.00
R9780:Nrxn1	UTSW	17	90,931,042 (GRCm39)	missense	possibly damaging	0.54
RF005:Nrxn1	UTSW	17	90,670,304 (GRCm39)	missense	probably damaging	1.00
RF024:Nrxn1	UTSW	17	90,670,304 (GRCm39)	missense	probably damaging	1.00
X0021:Nrxn1	UTSW	17	90,897,640 (GRCm39)	missense	probably damaging	1.00
X0063:Nrxn1	UTSW	17	90,670,259 (GRCm39)	missense	possibly damaging	0.54
Z1088:Nrxn1	UTSW	17	90,366,933 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-10-07