Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01318:Kcnma1'

73957

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Kcnma1

Ensembl Gene

ENSMUSG00000063142

Gene Name

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Synonyms

MaxiK, BKCa, 5730414M22Rik, BK channel alpha subunit, Slo, Slo1, mSlo1

Accession Numbers

Essential gene?

Probably essential (E-score: 0.856) question?

Stock #

IGL01318

Quality Score

Status

Chromosome

Chromosomal Location

23342356-24055173 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 23364390 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000153254 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000065788] [ENSMUST00000074983] [ENSMUST00000100831] [ENSMUST00000112423] [ENSMUST00000145596] [ENSMUST00000163322] [ENSMUST00000172099] [ENSMUST00000177634] [ENSMUST00000179836] [ENSMUST00000188210] [ENSMUST00000188991] [ENSMUST00000190044] [ENSMUST00000190985] [ENSMUST00000179097] [ENSMUST00000188285] [ENSMUST00000223655] [ENSMUST00000223727] [ENSMUST00000223749] [ENSMUST00000224077] [ENSMUST00000224232] [ENSMUST00000224285] [ENSMUST00000224468] [ENSMUST00000224787] [ENSMUST00000224812] [ENSMUST00000225315] [ENSMUST00000225431] [ENSMUST00000225471] [ENSMUST00000225556] [ENSMUST00000225794]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000065788

SMART Domains

Protein: ENSMUSP00000065293
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	20	31	N/A	INTRINSIC
transmembrane domain	54	73	N/A	INTRINSIC
Pfam:Ion_trans	91	262	2.2e-18	PFAM
Pfam:Ion_trans_2	180	268	5.7e-16	PFAM
Pfam:TrkA_N	314	413	7.5e-7	PFAM
Pfam:BK_channel_a	411	509	6.4e-31	PFAM
low complexity region	835	843	N/A	INTRINSIC
low complexity region	891	902	N/A	INTRINSIC
low complexity region	1005	1031	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000074983

SMART Domains

Protein: ENSMUSP00000074511
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	20	31	N/A	INTRINSIC
transmembrane domain	54	73	N/A	INTRINSIC
Pfam:Ion_trans	91	262	2.2e-18	PFAM
Pfam:Ion_trans_2	180	268	5.7e-16	PFAM
Pfam:TrkA_N	314	413	7.5e-7	PFAM
Pfam:BK_channel_a	411	509	6.4e-31	PFAM
low complexity region	894	902	N/A	INTRINSIC
low complexity region	950	961	N/A	INTRINSIC
low complexity region	1064	1090	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000100831

SMART Domains

Protein: ENSMUSP00000098393
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	20	31	N/A	INTRINSIC
transmembrane domain	54	73	N/A	INTRINSIC
Pfam:Ion_trans	91	262	2.1e-18	PFAM
Pfam:Ion_trans_2	180	268	5.5e-16	PFAM
Pfam:TrkA_N	314	413	7.3e-7	PFAM
Pfam:BK_channel_a	411	509	6.2e-31	PFAM
low complexity region	865	873	N/A	INTRINSIC
low complexity region	921	932	N/A	INTRINSIC
low complexity region	1035	1061	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000112423

SMART Domains

Protein: ENSMUSP00000108042
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
transmembrane domain	2	19	N/A	INTRINSIC
Pfam:Ion_trans	37	208	2.1e-18	PFAM
Pfam:Ion_trans_2	126	214	5.3e-16	PFAM
Pfam:TrkA_N	260	359	7e-7	PFAM
Pfam:BK_channel_a	357	455	6e-31	PFAM
low complexity region	781	789	N/A	INTRINSIC
low complexity region	837	848	N/A	INTRINSIC
low complexity region	951	977	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000145596

Predicted Effect

probably benign
Transcript: ENSMUST00000163322

SMART Domains

Protein: ENSMUSP00000128553
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	20	31	N/A	INTRINSIC
transmembrane domain	54	73	N/A	INTRINSIC
Pfam:Ion_trans	91	262	3.2e-18	PFAM
Pfam:Ion_trans_2	180	268	1.1e-15	PFAM
Pfam:TrkA_N	314	413	7e-7	PFAM
Pfam:BK_channel_a	411	509	6e-31	PFAM
low complexity region	832	840	N/A	INTRINSIC
low complexity region	888	899	N/A	INTRINSIC
low complexity region	1002	1028	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000172099

SMART Domains

Protein: ENSMUSP00000132204
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	20	31	N/A	INTRINSIC
transmembrane domain	54	73	N/A	INTRINSIC
Pfam:Ion_trans	91	262	2.2e-18	PFAM
Pfam:Ion_trans_2	180	268	5.7e-16	PFAM
Pfam:TrkA_N	314	413	7.6e-7	PFAM
Pfam:BK_channel_a	411	509	6.5e-31	PFAM
low complexity region	897	905	N/A	INTRINSIC
low complexity region	953	964	N/A	INTRINSIC
low complexity region	1067	1093	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000177634

SMART Domains

Protein: ENSMUSP00000136447
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	20	31	N/A	INTRINSIC
Pfam:Ion_trans	53	272	4.9e-19	PFAM
Pfam:Ion_trans_2	180	267	1.2e-15	PFAM
Pfam:BK_channel_a	413	508	1.2e-35	PFAM
low complexity region	862	870	N/A	INTRINSIC
low complexity region	918	929	N/A	INTRINSIC
low complexity region	1032	1058	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000179836

SMART Domains

Protein: ENSMUSP00000137141
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	20	31	N/A	INTRINSIC
transmembrane domain	54	73	N/A	INTRINSIC
Pfam:Ion_trans	91	262	4.2e-18	PFAM
Pfam:Ion_trans_2	180	268	9.5e-16	PFAM
Pfam:BK_channel_a	389	457	2.4e-15	PFAM
low complexity region	838	846	N/A	INTRINSIC
low complexity region	894	905	N/A	INTRINSIC
low complexity region	1008	1034	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000188210

SMART Domains

Protein: ENSMUSP00000141069
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	4	23	N/A	INTRINSIC
transmembrane domain	86	108	N/A	INTRINSIC
low complexity region	145	156	N/A	INTRINSIC
transmembrane domain	179	198	N/A	INTRINSIC
Pfam:Ion_trans	216	387	1.3e-18	PFAM
Pfam:Ion_trans_2	305	393	5.2e-16	PFAM
Pfam:TrkA_N	439	538	7.8e-7	PFAM
Pfam:BK_channel_a	536	634	5e-31	PFAM
low complexity region	988	996	N/A	INTRINSIC
low complexity region	1044	1055	N/A	INTRINSIC
low complexity region	1158	1184	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000188991

SMART Domains

Protein: ENSMUSP00000140751
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	4	23	N/A	INTRINSIC
transmembrane domain	86	108	N/A	INTRINSIC
low complexity region	145	156	N/A	INTRINSIC
transmembrane domain	179	198	N/A	INTRINSIC
Pfam:Ion_trans	216	387	3.3e-18	PFAM
Pfam:Ion_trans_2	305	393	1.1e-15	PFAM
Pfam:TrkA_N	439	538	3.7e-7	PFAM
Pfam:BK_channel_a	536	634	3.4e-31	PFAM
low complexity region	1015	1023	N/A	INTRINSIC
low complexity region	1071	1082	N/A	INTRINSIC
low complexity region	1185	1211	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000190044

SMART Domains

Protein: ENSMUSP00000140033
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	4	23	N/A	INTRINSIC
transmembrane domain	86	108	N/A	INTRINSIC
low complexity region	145	156	N/A	INTRINSIC
transmembrane domain	179	198	N/A	INTRINSIC
Pfam:Ion_trans	216	387	1.3e-18	PFAM
Pfam:Ion_trans_2	305	393	5.1e-16	PFAM
Pfam:TrkA_N	439	538	7.5e-7	PFAM
Pfam:BK_channel_a	536	634	4.9e-31	PFAM
low complexity region	957	965	N/A	INTRINSIC
low complexity region	1013	1024	N/A	INTRINSIC
low complexity region	1127	1153	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000190985

Predicted Effect

probably benign
Transcript: ENSMUST00000179097

SMART Domains

Protein: ENSMUSP00000136568
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	20	31	N/A	INTRINSIC
transmembrane domain	54	73	N/A	INTRINSIC
Pfam:Ion_trans	91	262	4.6e-18	PFAM
Pfam:Ion_trans_2	180	268	1e-15	PFAM
Pfam:TrkA_N	314	413	1.1e-7	PFAM
Pfam:BK_channel_a	411	509	3.2e-31	PFAM
low complexity region	859	867	N/A	INTRINSIC
low complexity region	915	926	N/A	INTRINSIC
low complexity region	1029	1055	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000188285

SMART Domains

Protein: ENSMUSP00000140275
Gene: ENSMUSG00000063142

Domain	Start	End	E-Value	Type
low complexity region	4	23	N/A	INTRINSIC
transmembrane domain	86	108	N/A	INTRINSIC
low complexity region	145	156	N/A	INTRINSIC
transmembrane domain	179	198	N/A	INTRINSIC
Pfam:Ion_trans	216	387	1.3e-18	PFAM
Pfam:Ion_trans_2	305	393	5.4e-16	PFAM
Pfam:TrkA_N	439	538	8e-7	PFAM
Pfam:BK_channel_a	536	634	5.2e-31	PFAM
low complexity region	1019	1027	N/A	INTRINSIC
low complexity region	1075	1086	N/A	INTRINSIC
low complexity region	1189	1215	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000223655

Predicted Effect

probably benign
Transcript: ENSMUST00000223727

Predicted Effect

probably benign
Transcript: ENSMUST00000223749

Predicted Effect

probably benign
Transcript: ENSMUST00000224025

Predicted Effect

probably benign
Transcript: ENSMUST00000224077

Predicted Effect

probably benign
Transcript: ENSMUST00000224232

Predicted Effect

probably benign
Transcript: ENSMUST00000224285

Predicted Effect

probably benign
Transcript: ENSMUST00000224468

Predicted Effect

probably benign
Transcript: ENSMUST00000224787

Predicted Effect

probably benign
Transcript: ENSMUST00000224812

Predicted Effect

probably benign
Transcript: ENSMUST00000225315

Predicted Effect

probably benign
Transcript: ENSMUST00000225431

Predicted Effect

probably benign
Transcript: ENSMUST00000225471

Predicted Effect

probably benign
Transcript: ENSMUST00000225556

Predicted Effect

probably benign
Transcript: ENSMUST00000225794

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous inactivation of this gene leads to cerebellar ataxia, Purkinje cell dysfunction, uneven gait patterns, bladder hyperactivity, urinary incontinence, abnormal colonic K+ secretion, and hearing impairment. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Alg10b	T	C	15: 90,112,592 (GRCm39)		probably benign	Het
Ambn	T	C	5: 88,608,554 (GRCm39)		probably benign	Het
Asap2	A	G	12: 21,297,296 (GRCm39)	D585G	probably null	Het
Chaf1a	G	T	17: 56,366,336 (GRCm39)		probably benign	Het
Ddhd1	A	G	14: 45,854,008 (GRCm39)	S443P	probably damaging	Het
Dlk2	A	G	17: 46,613,390 (GRCm39)	E215G	probably damaging	Het
Efhd2	T	C	4: 141,587,176 (GRCm39)	N202S	probably benign	Het
Gkap1	A	T	13: 58,384,853 (GRCm39)	I308K	probably damaging	Het
Gm9848	T	A	13: 113,244,774 (GRCm39)		noncoding transcript	Het
Hmcn1	G	A	1: 150,594,991 (GRCm39)	T1826I	probably damaging	Het
Htr5a	T	C	5: 28,047,742 (GRCm39)	V99A	probably benign	Het
Inha	T	G	1: 75,486,572 (GRCm39)	F289C	probably damaging	Het
Kcna3	T	C	3: 106,945,294 (GRCm39)	V519A	probably benign	Het
Kctd1	A	G	18: 15,195,747 (GRCm39)	V292A	possibly damaging	Het
Magea13	T	A	X: 57,964,829 (GRCm39)	I196N	probably damaging	Het
Map2k4	A	G	11: 65,647,089 (GRCm39)		probably benign	Het
Mfap2	G	T	4: 140,742,856 (GRCm39)	A175S	possibly damaging	Het
Milr1	G	A	11: 106,656,071 (GRCm39)	A114T	possibly damaging	Het
Mogs	G	T	6: 83,095,558 (GRCm39)	V792F	probably damaging	Het
Nt5dc3	T	A	10: 86,661,089 (GRCm39)	M418K	possibly damaging	Het
Or5b12	A	G	19: 12,897,490 (GRCm39)	L61P	probably damaging	Het
Or7d10	A	G	9: 19,832,054 (GRCm39)	E183G	probably benign	Het
Or8h8	A	T	2: 86,753,293 (GRCm39)	N194K	probably benign	Het
Osbpl10	G	A	9: 115,061,190 (GRCm39)	W756*	probably null	Het
Pgam5	A	G	5: 110,413,391 (GRCm39)	Y235H	probably damaging	Het
Pgm5	G	T	19: 24,793,842 (GRCm39)	A274E	probably damaging	Het
Prex1	C	A	2: 166,411,260 (GRCm39)		probably benign	Het
Prps1l1	A	T	12: 35,035,377 (GRCm39)	N164I	probably benign	Het
Ralbp1	C	A	17: 66,171,277 (GRCm39)	R232L	probably damaging	Het
Rnaseh2a	C	T	8: 85,691,752 (GRCm39)		probably benign	Het
Stard9	A	T	2: 120,529,200 (GRCm39)	H1819L	possibly damaging	Het
Stom	T	A	2: 35,226,889 (GRCm39)	I15F	probably benign	Het
Tasor2	A	C	13: 3,625,067 (GRCm39)	S946A	possibly damaging	Het
Tph1	T	G	7: 46,314,662 (GRCm39)	T22P	probably damaging	Het
Uqcrfs1	A	G	13: 30,724,904 (GRCm39)	I212T	probably benign	Het
Ush2a	T	C	1: 188,546,550 (GRCm39)	I3442T	probably benign	Het
Vinac1	C	A	2: 128,880,622 (GRCm39)	V435L	probably benign	Het
Vmn2r113	A	G	17: 23,177,309 (GRCm39)	I698V	probably benign	Het
Vmn2r75	T	C	7: 85,814,774 (GRCm39)	I240V	probably benign	Het
Wdr17	T	C	8: 55,125,585 (GRCm39)	T432A	probably damaging	Het

Other mutations in Kcnma1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01520:Kcnma1	APN	14	23,551,211 (GRCm39)	missense	possibly damaging	0.94
IGL01977:Kcnma1	APN	14	23,580,367 (GRCm39)	splice site	probably benign
IGL02140:Kcnma1	APN	14	23,359,113 (GRCm39)	missense	probably damaging	1.00
IGL02165:Kcnma1	APN	14	23,387,035 (GRCm39)	missense	possibly damaging	0.93
IGL02186:Kcnma1	APN	14	23,576,881 (GRCm39)	missense	probably benign	0.28
IGL02268:Kcnma1	APN	14	23,593,144 (GRCm39)	missense	probably damaging	1.00
IGL02353:Kcnma1	APN	14	23,641,681 (GRCm39)	missense	probably damaging	1.00
IGL02360:Kcnma1	APN	14	23,641,681 (GRCm39)	missense	probably damaging	1.00
IGL02491:Kcnma1	APN	14	23,361,757 (GRCm39)	missense	probably damaging	1.00
IGL02552:Kcnma1	APN	14	23,436,327 (GRCm39)	critical splice donor site	probably null
IGL02625:Kcnma1	APN	14	23,413,900 (GRCm39)	missense	probably damaging	1.00
IGL02677:Kcnma1	APN	14	23,513,224 (GRCm39)	missense	probably damaging	1.00
IGL02706:Kcnma1	APN	14	23,359,222 (GRCm39)	missense	probably damaging	1.00
G1citation:Kcnma1	UTSW	14	24,053,812 (GRCm39)	splice site	probably null
PIT4495001:Kcnma1	UTSW	14	23,475,665 (GRCm39)	missense	probably benign	0.00
PIT4514001:Kcnma1	UTSW	14	23,359,103 (GRCm39)	splice site	probably null
PIT4576001:Kcnma1	UTSW	14	23,359,103 (GRCm39)	splice site	probably null
R0071:Kcnma1	UTSW	14	23,576,835 (GRCm39)	missense	probably damaging	1.00
R0071:Kcnma1	UTSW	14	23,576,835 (GRCm39)	missense	probably damaging	1.00
R0115:Kcnma1	UTSW	14	23,364,243 (GRCm39)	missense	probably damaging	1.00
R0172:Kcnma1	UTSW	14	23,853,234 (GRCm39)	missense	probably damaging	1.00
R0178:Kcnma1	UTSW	14	23,576,835 (GRCm39)	missense	probably damaging	1.00
R0183:Kcnma1	UTSW	14	23,558,120 (GRCm39)	missense	probably damaging	1.00
R0240:Kcnma1	UTSW	14	23,544,647 (GRCm39)	missense	probably damaging	1.00
R0240:Kcnma1	UTSW	14	23,544,647 (GRCm39)	missense	probably damaging	1.00
R0328:Kcnma1	UTSW	14	23,423,265 (GRCm39)	missense	probably damaging	1.00
R0501:Kcnma1	UTSW	14	23,361,784 (GRCm39)	missense	possibly damaging	0.80
R0631:Kcnma1	UTSW	14	23,559,852 (GRCm39)	splice site	probably benign
R0668:Kcnma1	UTSW	14	23,417,563 (GRCm39)	missense	probably damaging	1.00
R0811:Kcnma1	UTSW	14	23,350,086 (GRCm39)	missense	probably damaging	0.96
R0812:Kcnma1	UTSW	14	23,350,086 (GRCm39)	missense	probably damaging	0.96
R1080:Kcnma1	UTSW	14	23,544,675 (GRCm39)	missense	probably damaging	1.00
R1419:Kcnma1	UTSW	14	23,417,710 (GRCm39)	missense	probably damaging	0.99
R1446:Kcnma1	UTSW	14	23,361,792 (GRCm39)	missense	probably damaging	1.00
R1454:Kcnma1	UTSW	14	23,513,268 (GRCm39)	missense	probably damaging	1.00
R1651:Kcnma1	UTSW	14	23,364,262 (GRCm39)	missense	probably damaging	1.00
R1826:Kcnma1	UTSW	14	23,380,997 (GRCm39)	missense	probably damaging	1.00
R1827:Kcnma1	UTSW	14	23,380,997 (GRCm39)	missense	probably damaging	1.00
R1828:Kcnma1	UTSW	14	23,380,997 (GRCm39)	missense	probably damaging	1.00
R1864:Kcnma1	UTSW	14	23,853,230 (GRCm39)	missense	probably damaging	1.00
R2002:Kcnma1	UTSW	14	23,387,097 (GRCm39)	missense	probably damaging	0.99
R2140:Kcnma1	UTSW	14	23,364,288 (GRCm39)	missense	probably damaging	1.00
R2278:Kcnma1	UTSW	14	23,593,151 (GRCm39)	nonsense	probably null
R2866:Kcnma1	UTSW	14	23,423,275 (GRCm39)	missense	probably benign	0.16
R2867:Kcnma1	UTSW	14	23,423,275 (GRCm39)	missense	probably benign	0.16
R2867:Kcnma1	UTSW	14	23,423,275 (GRCm39)	missense	probably benign	0.16
R2900:Kcnma1	UTSW	14	23,853,228 (GRCm39)	missense	probably damaging	1.00
R3820:Kcnma1	UTSW	14	23,350,006 (GRCm39)	missense	possibly damaging	0.66
R3821:Kcnma1	UTSW	14	23,417,679 (GRCm39)	missense	probably damaging	1.00
R3901:Kcnma1	UTSW	14	23,555,323 (GRCm39)	missense	probably damaging	0.98
R3975:Kcnma1	UTSW	14	24,053,815 (GRCm39)	critical splice donor site	probably null
R3976:Kcnma1	UTSW	14	24,053,815 (GRCm39)	critical splice donor site	probably null
R4352:Kcnma1	UTSW	14	23,361,720 (GRCm39)	missense	probably damaging	1.00
R4517:Kcnma1	UTSW	14	23,387,097 (GRCm39)	missense	probably damaging	1.00
R4598:Kcnma1	UTSW	14	23,853,228 (GRCm39)	missense	probably damaging	1.00
R4604:Kcnma1	UTSW	14	23,359,106 (GRCm39)	critical splice donor site	probably null
R4743:Kcnma1	UTSW	14	23,853,270 (GRCm39)	missense	probably damaging	1.00
R4754:Kcnma1	UTSW	14	23,413,904 (GRCm39)	missense	probably damaging	0.96
R4908:Kcnma1	UTSW	14	23,359,220 (GRCm39)	missense	probably damaging	0.99
R4960:Kcnma1	UTSW	14	24,054,186 (GRCm39)	intron	probably benign
R5175:Kcnma1	UTSW	14	23,386,106 (GRCm39)	critical splice donor site	probably null
R5218:Kcnma1	UTSW	14	23,513,253 (GRCm39)	missense	probably damaging	0.96
R5435:Kcnma1	UTSW	14	23,578,472 (GRCm39)	nonsense	probably null
R5705:Kcnma1	UTSW	14	24,053,839 (GRCm39)	missense	possibly damaging	0.73
R5746:Kcnma1	UTSW	14	23,544,635 (GRCm39)	missense	probably damaging	1.00
R5780:Kcnma1	UTSW	14	23,436,419 (GRCm39)	nonsense	probably null
R5793:Kcnma1	UTSW	14	23,359,103 (GRCm39)	splice site	probably null
R6039:Kcnma1	UTSW	14	23,359,105 (GRCm39)	missense	probably benign	0.42
R6039:Kcnma1	UTSW	14	23,359,105 (GRCm39)	missense	probably benign	0.42
R6133:Kcnma1	UTSW	14	24,053,936 (GRCm39)	missense	probably damaging	0.98
R6271:Kcnma1	UTSW	14	23,559,957 (GRCm39)	missense	probably damaging	1.00
R6490:Kcnma1	UTSW	14	23,386,165 (GRCm39)	missense	possibly damaging	0.46
R6704:Kcnma1	UTSW	14	24,052,882 (GRCm39)	nonsense	probably null
R6822:Kcnma1	UTSW	14	24,053,812 (GRCm39)	splice site	probably null
R6855:Kcnma1	UTSW	14	23,417,679 (GRCm39)	missense	probably damaging	1.00
R6920:Kcnma1	UTSW	14	23,576,602 (GRCm39)	critical splice donor site	probably null
R7017:Kcnma1	UTSW	14	23,544,711 (GRCm39)	missense	possibly damaging	0.79
R7081:Kcnma1	UTSW	14	23,350,086 (GRCm39)	missense	probably damaging	0.96
R7113:Kcnma1	UTSW	14	23,513,224 (GRCm39)	missense	probably damaging	1.00
R7131:Kcnma1	UTSW	14	23,417,562 (GRCm39)	missense	probably damaging	1.00
R7172:Kcnma1	UTSW	14	23,576,691 (GRCm39)	missense	probably damaging	1.00
R7207:Kcnma1	UTSW	14	23,359,083 (GRCm39)	makesense	probably null
R7308:Kcnma1	UTSW	14	23,381,003 (GRCm39)	missense	probably damaging	0.99
R7371:Kcnma1	UTSW	14	23,544,638 (GRCm39)	missense	possibly damaging	0.94
R7404:Kcnma1	UTSW	14	24,052,902 (GRCm39)	missense	unknown
R7560:Kcnma1	UTSW	14	23,580,310 (GRCm39)	missense	probably benign	0.15
R7693:Kcnma1	UTSW	14	23,417,680 (GRCm39)	missense	probably damaging	1.00
R7763:Kcnma1	UTSW	14	23,350,074 (GRCm39)	missense	possibly damaging	0.66
R7809:Kcnma1	UTSW	14	23,423,324 (GRCm39)	missense	probably benign	0.16
R7832:Kcnma1	UTSW	14	23,440,991 (GRCm39)	missense	probably benign
R7884:Kcnma1	UTSW	14	23,387,057 (GRCm39)	missense	probably benign	0.01
R8013:Kcnma1	UTSW	14	23,423,211 (GRCm39)	missense	probably benign	0.31
R8014:Kcnma1	UTSW	14	23,423,211 (GRCm39)	missense	probably benign	0.31
R8066:Kcnma1	UTSW	14	23,361,744 (GRCm39)	missense	probably benign	0.00
R8097:Kcnma1	UTSW	14	23,381,032 (GRCm39)	missense	probably damaging	1.00
R8154:Kcnma1	UTSW	14	23,361,822 (GRCm39)	missense	possibly damaging	0.62
R8507:Kcnma1	UTSW	14	23,641,706 (GRCm39)	missense	probably benign	0.00
R8672:Kcnma1	UTSW	14	23,551,230 (GRCm39)	missense	probably damaging	1.00
R8677:Kcnma1	UTSW	14	23,436,418 (GRCm39)	missense	probably benign	0.36
R8725:Kcnma1	UTSW	14	23,436,332 (GRCm39)	missense	probably benign	0.00
R8727:Kcnma1	UTSW	14	23,436,332 (GRCm39)	missense	probably benign	0.00
R8827:Kcnma1	UTSW	14	23,417,548 (GRCm39)	missense	probably damaging	1.00
R8880:Kcnma1	UTSW	14	23,417,718 (GRCm39)	missense	probably damaging	1.00
R8997:Kcnma1	UTSW	14	23,513,037 (GRCm39)	intron	probably benign
R9056:Kcnma1	UTSW	14	23,700,214 (GRCm39)	missense	possibly damaging	0.80
R9346:Kcnma1	UTSW	14	23,700,233 (GRCm39)	missense	possibly damaging	0.94
R9403:Kcnma1	UTSW	14	23,593,145 (GRCm39)	missense	probably benign	0.05
R9438:Kcnma1	UTSW	14	23,417,653 (GRCm39)	missense	probably benign	0.00
R9482:Kcnma1	UTSW	14	23,441,033 (GRCm39)	missense	probably benign
R9511:Kcnma1	UTSW	14	23,361,793 (GRCm39)	missense	possibly damaging	0.90
R9649:Kcnma1	UTSW	14	23,501,666 (GRCm39)	critical splice donor site	probably null
R9663:Kcnma1	UTSW	14	24,053,897 (GRCm39)	missense	probably benign	0.15
R9673:Kcnma1	UTSW	14	23,558,123 (GRCm39)	missense	probably benign	0.01
RF001:Kcnma1	UTSW	14	23,361,765 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-10-07