Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01329:Vmn1r205'

74411

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r205

Ensembl Gene

ENSMUSG00000100296

Gene Name

vomeronasal 1 receptor 205

Synonyms

V1rh8

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.140) question?

Stock #

IGL01329

Quality Score

Status

Chromosome

Chromosomal Location

22776150-22777100 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 22776273 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Methionine at position 276 (I276M)

Ref Sequence

ENSEMBL: ENSMUSP00000073934 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074324] [ENSMUST00000185475]

AlphaFold

Q8R276

Predicted Effect

probably benign
Transcript: ENSMUST00000074324
AA Change: I276M

PolyPhen 2 Score 0.060 (Sensitivity: 0.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000073934
Gene: ENSMUSG00000101073
AA Change: I276M

Domain	Start	End	E-Value	Type
Pfam:V1R	24	307	5.5e-36	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000185475
AA Change: I276M

PolyPhen 2 Score 0.052 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000139977
Gene: ENSMUSG00000100296
AA Change: I276M

Domain	Start	End	E-Value	Type
Pfam:V1R	24	307	5.5e-36	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb4	T	C	5: 8,944,166 (GRCm39)		probably null	Het
Ankib1	A	T	5: 3,784,194 (GRCm39)		probably benign	Het
Birc2	T	C	9: 7,860,733 (GRCm39)	Y195C	probably damaging	Het
Cand2	T	C	6: 115,759,755 (GRCm39)	I142T	probably benign	Het
Cdh15	T	C	8: 123,592,062 (GRCm39)		probably benign	Het
Ceacam5	G	A	7: 17,479,534 (GRCm39)	G217D	probably damaging	Het
Cfap54	T	A	10: 92,917,385 (GRCm39)	H25L	unknown	Het
Cfap95	A	G	19: 23,630,100 (GRCm39)		probably benign	Het
Col22a1	A	G	15: 71,778,889 (GRCm39)	V266A	probably benign	Het
D3Ertd751e	A	G	3: 41,703,132 (GRCm39)	D69G	probably benign	Het
Dnah3	T	C	7: 119,622,164 (GRCm39)	I1518V	probably damaging	Het
Entpd8	A	G	2: 24,974,358 (GRCm39)	K381R	probably benign	Het
Fli1	T	A	9: 32,335,397 (GRCm39)	K345I	probably damaging	Het
G6pd2	T	C	5: 61,967,281 (GRCm39)	V352A	probably damaging	Het
Gbp11	C	T	5: 105,475,482 (GRCm39)		probably null	Het
Gm11992	A	G	11: 9,018,383 (GRCm39)	*292W	probably null	Het
Ifnar2	T	A	16: 91,188,599 (GRCm39)		probably benign	Het
Impg1	T	C	9: 80,230,111 (GRCm39)	K661R	probably benign	Het
Inf2	G	T	12: 112,578,290 (GRCm39)	E651*	probably null	Het
Ints1	A	G	5: 139,753,258 (GRCm39)		probably benign	Het
Iqcf4	T	C	9: 106,447,832 (GRCm39)	K26E	probably benign	Het
Map4k3	A	G	17: 80,951,613 (GRCm39)	V289A	probably benign	Het
Mis18bp1	T	C	12: 65,205,215 (GRCm39)	K319R	possibly damaging	Het
Nubpl	T	C	12: 52,352,638 (GRCm39)	V291A	probably damaging	Het
Or4f56	A	G	2: 111,703,295 (GRCm39)	F302L	probably benign	Het
Or4k15c	C	T	14: 50,321,454 (GRCm39)	R228H	probably benign	Het
Or8b57	A	G	9: 40,003,324 (GRCm39)	S313P	possibly damaging	Het
Or8k38	T	C	2: 86,488,551 (GRCm39)	N84D	probably benign	Het
Otof	A	G	5: 30,598,723 (GRCm39)	S29P	probably benign	Het
Pcca	A	G	14: 122,927,545 (GRCm39)	D436G	possibly damaging	Het
Rasef	T	A	4: 73,645,882 (GRCm39)	T496S	probably damaging	Het
Saa2	A	G	7: 46,402,896 (GRCm39)	D49G	probably benign	Het
Scart1	T	A	7: 139,804,552 (GRCm39)		probably null	Het
Scn2a	A	G	2: 65,547,852 (GRCm39)	I1015V	probably benign	Het
Sim2	T	C	16: 93,907,119 (GRCm39)	Y154H	possibly damaging	Het
Spag17	A	G	3: 100,002,865 (GRCm39)	H1863R	probably benign	Het
Supt16	C	T	14: 52,414,489 (GRCm39)	E438K	probably benign	Het
Svil	A	G	18: 5,064,501 (GRCm39)	E1111G	probably benign	Het
Trabd2b	T	C	4: 114,266,322 (GRCm39)	V112A	probably damaging	Het
Vps13d	A	T	4: 144,882,776 (GRCm39)	I939N	possibly damaging	Het
Zc3h11a	T	C	1: 133,553,600 (GRCm39)	M515V	probably benign	Het
Zfp457	T	C	13: 67,442,330 (GRCm39)	T82A	possibly damaging	Het

Other mutations in Vmn1r205

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02148:Vmn1r205	APN	13	22,776,395 (GRCm39)	missense	probably damaging	1.00
IGL02608:Vmn1r205	APN	13	22,776,370 (GRCm39)	missense	probably damaging	1.00
IGL03140:Vmn1r205	APN	13	22,776,746 (GRCm39)	missense	possibly damaging	0.78
R0831:Vmn1r205	UTSW	13	22,776,586 (GRCm39)	missense	probably benign	0.12
R1418:Vmn1r205	UTSW	13	22,777,049 (GRCm39)	missense	probably benign	0.00
R1873:Vmn1r205	UTSW	13	22,776,223 (GRCm39)	missense	possibly damaging	0.95
R2358:Vmn1r205	UTSW	13	22,776,566 (GRCm39)	missense	probably benign	0.11
R2434:Vmn1r205	UTSW	13	22,776,524 (GRCm39)	missense	probably benign	0.37
R3105:Vmn1r205	UTSW	13	22,777,109 (GRCm39)	unclassified	probably benign
R3725:Vmn1r205	UTSW	13	22,776,671 (GRCm39)	missense	probably damaging	1.00
R4758:Vmn1r205	UTSW	13	22,777,016 (GRCm39)	missense	possibly damaging	0.49
R4851:Vmn1r205	UTSW	13	22,777,074 (GRCm39)	missense	probably benign	0.15
R5642:Vmn1r205	UTSW	13	22,776,206 (GRCm39)	missense	probably benign	0.16
R6447:Vmn1r205	UTSW	13	22,776,912 (GRCm39)	missense	probably damaging	1.00
R7453:Vmn1r205	UTSW	13	22,776,931 (GRCm39)	missense	probably damaging	0.99
R8177:Vmn1r205	UTSW	13	22,776,415 (GRCm39)	missense	probably benign	0.03
R8813:Vmn1r205	UTSW	13	22,776,424 (GRCm39)	missense	probably benign	0.36

Posted On

2013-10-07