Incidental Mutation 'P0016:4930432E11Rik'
| ID |
7611 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
4930432E11Rik
|
| Ensembl Gene |
ENSMUSG00000046958 |
| Gene Name |
RIKEN cDNA 4930432E11 gene |
| Synonyms |
|
| MMRRC Submission |
038269-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.082)
|
| Stock # |
P0016 (G1)
|
| Quality Score |
|
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
29255998-29276204 bp(+) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
T to C
at 29262537 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000053635
|
| SMART Domains |
Protein: ENSMUSP00000049518
Gene: ENSMUSG00000046958
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:WD40
|
43 |
79 |
3e-11 |
BLAST |
|
WD40
|
131 |
172 |
1.97e2 |
SMART |
|
WD40
|
175 |
214 |
2.24e-2 |
SMART |
|
Blast:WD40
|
257 |
296 |
4e-15 |
BLAST |
|
WD40
|
393 |
437 |
1.32e2 |
SMART |
|
WD40
|
494 |
533 |
2.15e-4 |
SMART |
|
low complexity region
|
598 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1094 |
N/A |
INTRINSIC |
|
low complexity region
|
1107 |
1148 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000063585
|
| SMART Domains |
Protein: ENSMUSP00000063695
Gene: ENSMUSG00000051976
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
28 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
35 |
67 |
3.29e-5 |
PROSPERO |
|
internal_repeat_1
|
73 |
102 |
3.29e-5 |
PROSPERO |
|
low complexity region
|
122 |
135 |
N/A |
INTRINSIC |
|
coiled coil region
|
161 |
182 |
N/A |
INTRINSIC |
|
low complexity region
|
216 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
239 |
249 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185541
|
| Coding Region Coverage |
- 1x: 85.6%
- 3x: 81.0%
- 10x: 66.8%
- 20x: 50.1%
|
| Validation Efficiency |
96% (97/101) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 18 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700123K08Rik |
A |
T |
5: 138,561,200 (GRCm39) |
L154* |
probably null |
Het |
| Arap3 |
T |
A |
18: 38,117,401 (GRCm39) |
T892S |
probably benign |
Het |
| Ctnnd2 |
G |
A |
15: 30,967,084 (GRCm39) |
V987I |
probably benign |
Het |
| Dennd6b |
T |
C |
15: 89,071,180 (GRCm39) |
I351V |
probably benign |
Het |
| Kif27 |
G |
A |
13: 58,451,266 (GRCm39) |
Q1021* |
probably null |
Het |
| Klb |
G |
A |
5: 65,537,266 (GRCm39) |
W865* |
probably null |
Het |
| Mbd1 |
C |
T |
18: 74,407,609 (GRCm39) |
R130* |
probably null |
Het |
| Mroh7 |
T |
A |
4: 106,565,054 (GRCm39) |
|
probably null |
Het |
| Myo16 |
C |
T |
8: 10,450,596 (GRCm39) |
|
probably benign |
Het |
| Rbm22 |
T |
A |
18: 60,703,842 (GRCm39) |
|
probably benign |
Het |
| Rnaseh2a |
C |
G |
8: 85,686,429 (GRCm39) |
D206H |
probably damaging |
Het |
| Slain1 |
A |
G |
14: 103,923,110 (GRCm39) |
T187A |
probably benign |
Het |
| Slamf6 |
A |
G |
1: 171,764,068 (GRCm39) |
T154A |
probably damaging |
Het |
| Traip |
A |
G |
9: 107,845,855 (GRCm39) |
D316G |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,641,527 (GRCm39) |
D5196G |
probably damaging |
Het |
| Ubr5 |
C |
T |
15: 38,000,822 (GRCm39) |
V1569M |
probably damaging |
Het |
| Zfp750 |
T |
A |
11: 121,404,804 (GRCm39) |
K24* |
probably null |
Het |
| Zfp799 |
T |
C |
17: 33,038,331 (GRCm39) |
E645G |
possibly damaging |
Het |
|
| Other mutations in 4930432E11Rik |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01121:4930432E11Rik
|
APN |
7 |
29,273,426 (GRCm39) |
unclassified |
noncoding transcript |
|
|
IGL01955:4930432E11Rik
|
APN |
7 |
29,273,420 (GRCm39) |
unclassified |
noncoding transcript |
|
|
IGL01971:4930432E11Rik
|
APN |
7 |
29,273,987 (GRCm39) |
unclassified |
noncoding transcript |
|
|
IGL02132:4930432E11Rik
|
APN |
7 |
29,262,704 (GRCm39) |
unclassified |
noncoding transcript |
|
|
IGL02484:4930432E11Rik
|
APN |
7 |
29,262,777 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R0051:4930432E11Rik
|
UTSW |
7 |
29,278,526 (GRCm39) |
exon |
noncoding transcript |
|
|
R0060:4930432E11Rik
|
UTSW |
7 |
29,273,595 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R0094:4930432E11Rik
|
UTSW |
7 |
29,260,236 (GRCm39) |
exon |
noncoding transcript |
|
|
R0268:4930432E11Rik
|
UTSW |
7 |
29,274,027 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R0423:4930432E11Rik
|
UTSW |
7 |
29,261,825 (GRCm39) |
exon |
noncoding transcript |
|
|
R0478:4930432E11Rik
|
UTSW |
7 |
29,262,014 (GRCm39) |
exon |
noncoding transcript |
|
|
R0646:4930432E11Rik
|
UTSW |
7 |
29,260,710 (GRCm39) |
exon |
noncoding transcript |
|
|
R1208:4930432E11Rik
|
UTSW |
7 |
29,260,708 (GRCm39) |
exon |
noncoding transcript |
|
|
R1778:4930432E11Rik
|
UTSW |
7 |
29,260,131 (GRCm39) |
exon |
noncoding transcript |
|
|
R1779:4930432E11Rik
|
UTSW |
7 |
29,278,591 (GRCm39) |
exon |
noncoding transcript |
|
|
R1918:4930432E11Rik
|
UTSW |
7 |
29,273,514 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R2360:4930432E11Rik
|
UTSW |
7 |
29,274,214 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R3736:4930432E11Rik
|
UTSW |
7 |
29,273,996 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R3780:4930432E11Rik
|
UTSW |
7 |
29,260,263 (GRCm39) |
exon |
noncoding transcript |
|
|
R4427:4930432E11Rik
|
UTSW |
7 |
29,278,678 (GRCm39) |
exon |
noncoding transcript |
|
|
R4835:4930432E11Rik
|
UTSW |
7 |
29,274,326 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R4929:4930432E11Rik
|
UTSW |
7 |
29,273,467 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R5042:4930432E11Rik
|
UTSW |
7 |
29,273,927 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R5129:4930432E11Rik
|
UTSW |
7 |
29,260,786 (GRCm39) |
exon |
noncoding transcript |
|
|
R5371:4930432E11Rik
|
UTSW |
7 |
29,261,918 (GRCm39) |
exon |
noncoding transcript |
|
|
R5381:4930432E11Rik
|
UTSW |
7 |
29,262,393 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R5586:4930432E11Rik
|
UTSW |
7 |
29,277,153 (GRCm39) |
unclassified |
noncoding transcript |
|
|
R5874:4930432E11Rik
|
UTSW |
7 |
29,280,610 (GRCm39) |
exon |
noncoding transcript |
|
|
| Posted On |
2012-10-05 |
Incidental Mutation